CARLOS SIMON

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Obstetrics & Gynecology
Address
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    1. Garrido-Gomez T, Castillo-Marco N, Clemente-Ciscar M, Cordero T, Muñoz-Blat I, Amadoz A, Jimenez-Almazan J, Monfort-Ortiz R, Climent R, Perales-Marin A, Simon C. Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia. Elife. 2021 10 28; 10. PMID: 34709177.
      Citations:    Fields:    Translation:HumansCells
    2. Simon C. Consensus vision. Fertil Steril. 2021 07; 116(1):13-14. PMID: 34148581.
      Citations:    Fields:    Translation:Humans
    3. Simon C, Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L. In vitro fertilization and andrology laboratories in 2030. Fertil Steril. 2021 07; 116(1):2-3. PMID: 34148585.
      Citations:    Fields:    Translation:Humans
    4. Campbell A, Gardner DK, Meseguer M, Miller KA, Montag M, Palermo GD, Cheung S, Keating D, Xie P, Rosenwaks Z, Rienzi L, Innocenti F, Cimadomo D, Ubaldi FM, Sakkas D, Tucker MJ, Nel-Themaat L, Simon C. In vitro fertilization and andrology laboratory in 2030: expert visions. Fertil Steril. 2021 07; 116(1):4-12. PMID: 34148588.
      Citations:    Fields:    Translation:Humans
    5. Vilella F, Wang W, Moreno I, Quake SR, Simon C. Understanding the human endometrium in the 21st century. Am J Obstet Gynecol. 2021 07; 225(1):1-2. PMID: 34023092.
      Citations:    Fields:    Translation:Humans
    6. Ruiz-Alonso M, Valbuena D, Gomez C, Cuzzi J, Simon C. Endometrial Receptivity Analysis (ERA): data versus opinions. Hum Reprod Open. 2021; 2021(2):hoab011. PMID: 33880420.
      Citations: 1     
    7. Rubio C, Racowsky C, Barad DH, Scott RT, Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent culture medium as a substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):841-849. PMID: 33741125.
      Citations: 1     Fields:    Translation:Humans
    8. Simon C. Noninvasive preimplantation genetic testing for aneuploidy in spent blastocyst media will substitute for trophectoderm biopsy. Fertil Steril. 2021 04; 115(4):840. PMID: 33726897.
      Citations:    Fields:    Translation:Humans
    9. O'Brien JE, Adashi EY, Simon C. Darwin meets Mendel in the reproductive medicine field: Homo sapiens 2.0 is inevitable. Fertil Steril. 2021 04; 115(4):850-851. PMID: 33642062.
      Citations:    Fields:    Translation:Humans
    10. Vilella F, Simon C. Reproductive medicine, as seen through single-cell glasses. Fertil Steril. 2021 02; 115(2):296-297. PMID: 33386110.
      Citations:    Fields:    Translation:Humans
    11. Wang W, Vilella F, Alama P, Moreno I, Mignardi M, Isakova A, Pan W, Simon C, Quake SR. Single-cell transcriptomic atlas of the human endometrium during the menstrual cycle. Nat Med. 2020 10; 26(10):1644-1653. PMID: 32929266.
      Citations: 22     Fields:    Translation:HumansCells
    12. Critchley HOD, Babayev E, Bulun SE, Clark S, Garcia-Grau I, Gregersen PK, Kilcoyne A, Kim JJ, Lavender M, Marsh EE, Matteson KA, Maybin JA, Metz CN, Moreno I, Silk K, Sommer M, Simon C, Tariyal R, Taylor HS, Wagner GP, Griffith LG. Menstruation: science and society. Am J Obstet Gynecol. 2020 11; 223(5):624-664. PMID: 32707266.
      Citations: 9     Fields:    Translation:HumansCells
    13. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 Jul 02. PMID: 32624212.
      Citations:    Fields:    
    14. Simon C. Introduction: How evident is the evidence? Fertil Steril. 2020 06; 113(6):1091-1092. PMID: 32482243.
      Citations: 1     Fields:    Translation:Humans
    15. Roque M, Simon C. Time to pregnancy: as important for patients as underestimated by doctors. Fertil Steril. 2020 03; 113(3):522-523. PMID: 32111473.
      Citations:    Fields:    Translation:Humans
    16. Simon C. Operative hysteroscopy should be repeated as many times as necessary for the treatment of refractory Asherman syndrome versus is there any alternative therapy worth considering? Fertil Steril. 2020 03; 113(3):510. PMID: 32089254.
      Citations:    Fields:    Translation:Humans
    17. Simon C, Sakkas D, Gardner D, Critchley H. Precision medicine in human reproduction. Special Issue. Biol Reprod. 2019 12 24; 101(6):1075. PMID: 31616936.
      Citations: 2     Fields:    Translation:Humans
    18. Garcia-Grau I, Simon C, Moreno I. Uterine microbiome-low biomass and high expectations†. Biol Reprod. 2019 12 24; 101(6):1102-1114. PMID: 30544156.
      Citations: 6     Fields:    Translation:Humans
    19. Garrido-Gomez T, Quiñonero A, Dominguez F, Rubert L, Perales A, Hajjar KA, Simon C. Preeclampsia: a defect in decidualization is associated with deficiency of Annexin A2. Am J Obstet Gynecol. 2020 04; 222(4):376.e1-376.e17. PMID: 31738896.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    20. Garcia-Grau I, Perez-Villaroya D, Bau D, Gonzalez-Monfort M, Vilella F, Moreno I, Simon C. Taxonomical and Functional Assessment of the Endometrial Microbiota in A Context of Recurrent Reproductive Failure: A Case Report. Pathogens. 2019 Oct 24; 8(4). PMID: 31653041.
      Citations: 8     
    21. Niederberger C, Pellicer A, Simon C. Happy Birthday to ASRM from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e1. PMID: 31623722.
      Citations:    Fields:    Translation:Humans
    22. Niederberger C, Pellicer A, Simon C, Kathrins M, Goldstein M, Sigman M, Schlegel PN, Munné S, Gardner DK, Cobo A, Coutifaris C, Donnez J, Taylor HS, Giudice LC, Fauser BCJM, Lindheim SR, Rosenwaks Z, Casper RF, de Ziegler D, Gibbons WE, Paulson RJ, Laufer N, Klock SC, Mendola P, Sauer MV. 25 historic papers: an ASRM 75th birthday gift from Fertility and Sterility. Fertil Steril. 2019 10; 112(4 Suppl1):e2-e27. PMID: 31623734.
      Citations:    Fields:    Translation:Humans
    23. Simon C. Introduction: Preconceptional care: do we have to care? Fertil Steril. 2019 10; 112(4):611-612. PMID: 31561862.
      Citations: 1     Fields:    Translation:Humans
    24. Carrasquillo RJ, Kohn TP, Cinnioglu C, Rubio C, Simon C, Ramasamy R, Al-Asmar N. Advanced paternal age does not affect embryo aneuploidy following blastocyst biopsy in egg donor cycles. J Assist Reprod Genet. 2019 Oct; 36(10):2039-2045. PMID: 31385121.
      Citations: 3     Fields:    Translation:Humans
    25. Bulletti C, Simon C. Bioengineered uterus: a path toward ectogenesis. Fertil Steril. 2019 09; 112(3):446-447. PMID: 31371052.
      Citations: 1     Fields:    Translation:Humans
    26. Simon C, Romero R. Preconceptional care, where reproductive medicine meets obstetrics: the origins of lifetime health. Fertil Steril. 2019 04; 111(4):657-658. PMID: 30929724.
      Citations:    Fields:    Translation:Humans
    27. Moreno I, Simon C. An endometrial pathology in the inflammation cloud that can be accessed with a microbial app. Fertil Steril. 2019 04; 111(4):679-680. PMID: 30871763.
      Citations:    Fields:    Translation:Humans
    28. Santamaria X, Mas A, Cervelló I, Taylor HS, Simon C. Reply: Bone marrow-derived endometrial cells: what you see is what you get. Hum Reprod Update. 2019 03 01; 25(2):274-275. PMID: 30601981.
      Citations: 1     Fields:    Translation:HumansCells
    29. Simon C. To what extent is the testing of the reproductive risk of a couple aiming to conceive meaningful in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):227-228. PMID: 30642572.
      Citations:    Fields:    Translation:Humans
    30. Capalbo A, Chokoshvili D, Dugoff L, Franasiak J, Gleicher N, Pennings G, Simon C. Should the reproductive risk of a couple aiming to conceive be tested in the contemporary clinical context? Fertil Steril. 2019 02; 111(2):229-238. PMID: 30642571.
      Citations:    Fields:    Translation:Humans
    31. Santamaria X, Mas A, Cervelló I, Taylor H, Simon C. Uterine stem cells: from basic research to advanced cell therapies. Hum Reprod Update. 2018 11 01; 24(6):673-693. PMID: 30239705.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    32. Moreno I, Simon C. Deciphering the effect of reproductive tract microbiota on human reproduction. Reprod Med Biol. 2019 Jan; 18(1):40-50. PMID: 30655720.
      Citations: 15     
    33. Moreno I, Simon C. Relevance of assessing the uterine microbiota in infertility. Fertil Steril. 2018 08; 110(3):337-343. PMID: 30098680.
      Citations: 23     Fields:    Translation:HumansCells
    34. Simon C. Introduction: Do microbes in the female reproductive function matter? Fertil Steril. 2018 08; 110(3):325-326. PMID: 30037698.
      Citations: 7     Fields:    Translation:Humans
    35. Niederberger C, Pellicer A, Cohen J, Gardner DK, Palermo GD, O'Neill CL, Chow S, Rosenwaks Z, Cobo A, Swain JE, Schoolcraft WB, Frydman R, Bishop LA, Aharon D, Gordon C, New E, Decherney A, Tan SL, Paulson RJ, Goldfarb JM, Brännström M, Donnez J, Silber S, Dolmans MM, Simpson JL, Handyside AH, Munné S, Eguizabal C, Montserrat N, Izpisua Belmonte JC, Trounson A, Simon C, Tulandi T, Giudice LC, Norman RJ, Hsueh AJ, Sun Y, Laufer N, Kochman R, Eldar-Geva T, Lunenfeld B, Ezcurra D, D'Hooghe T, Fauser BCJM, Tarlatzis BC, Meldrum DR, Casper RF, Fatemi HM, Devroey P, Galliano D, Wikland M, Sigman M, Schoor RA, Goldstein M, Lipshultz LI, Schlegel PN, Hussein A, Oates RD, Brannigan RE, Ross HE, Pennings G, Klock SC, Brown S, Van Steirteghem A, Rebar RW, LaBarbera AR. Forty years of IVF. Fertil Steril. 2018 07 15; 110(2):185-324.e5. PMID: 30053940.
      Citations: 33     Fields:    Translation:Humans
    36. Simon C, Greening DW, Bolumar D, Balaguer N, Salamonsen LA, Vilella F. Extracellular Vesicles in Human Reproduction in Health and Disease. Endocr Rev. 2018 06 01; 39(3):292-332. PMID: 29390102.
      Citations: 35     Fields:    Translation:HumansCells
    37. Milan M, Mateu E, Blesa D, Clemente-Ciscar M, Simon C. Fetal sex determination in twin pregnancies using cell free fetal DNA analysis. Prenat Diagn. 2018 Apr 23. PMID: 29683524.
      Citations: 6     Fields:    
    38. Moreno I, Cicinelli E, Garcia-Grau I, Gonzalez-Monfort M, Bau D, Vilella F, De Ziegler D, Resta L, Valbuena D, Simon C. The diagnosis of chronic endometritis in infertile asymptomatic women: a comparative study of histology, microbial cultures, hysteroscopy, and molecular microbiology. Am J Obstet Gynecol. 2018 06; 218(6):602.e1-602.e16. PMID: 29477653.
      Citations: 18     Fields:    Translation:HumansCells
    39. Valdes CT, Schutt A, Simon C. Implantation failure of endometrial origin: it is not pathology, but our failure to synchronize the developing embryo with a receptive endometrium. Fertil Steril. 2017 07; 108(1):15-18. PMID: 28668151.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    40. Valbuena D, Valdes CT, Simon C. Introduction: Endometrial function: facts, urban legends, and an eye to the future. Fertil Steril. 2017 07; 108(1):4-8. PMID: 28601409.
      Citations: 4     Fields:    Translation:HumansAnimals
    41. Simon C. Introduction: To transfer or not transfer…a mosaic embryo, that is the question. Fertil Steril. 2017 05; 107(5):1083-1084. PMID: 28433365.
      Citations: 1     Fields:    Translation:Humans
    42. Simon C. Why should patients experience infertility or poor outcomes before using assisted reproductive technologies? Fertil Steril. 2017 04; 107(4):878-879. PMID: 28366414.
      Citations:    Fields:    Translation:Humans
    43. Comstock IA, Diaz-Gimeno P, Cabanillas S, Bellver J, Sebastian-Leon P, Shah M, Schutt A, Valdes CT, Ruiz-Alonso M, Valbuena D, Simon C, Lathi RB. Does an increased body mass index affect endometrial gene expression patterns in infertile patients? A functional genomics analysis. Fertil Steril. 2017 Mar; 107(3):740-748.e2. PMID: 27919438.
      Citations: 6     Fields:    Translation:HumansCells
    44. Moreno I, Codoñer FM, Vilella F, Valbuena D, Martinez-Blanch JF, Jimenez-Almazán J, Alonso R, Alamá P, Remohí J, Pellicer A, Ramon D, Simon C. Evidence that the endometrial microbiota has an effect on implantation success or failure. Am J Obstet Gynecol. 2016 Dec; 215(6):684-703. PMID: 27717732.
      Citations: 108     Fields:    Translation:HumansCells
    45. Medrano JV, Rombaut C, Simon C, Pellicer A, Goossens E. Human spermatogonial stem cells display limited proliferation in vitro under mouse spermatogonial stem cell culture conditions. Fertil Steril. 2016 Nov; 106(6):1539-1549.e8. PMID: 27490045.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    46. Sermon K, Capalbo A, Cohen J, Coonen E, De Rycke M, De Vos A, Delhanty J, Fiorentino F, Gleicher N, Griesinger G, Grifo J, Handyside A, Harper J, Kokkali G, Mastenbroek S, Meldrum D, Meseguer M, Montag M, Munné S, Rienzi L, Rubio C, Scott K, Scott R, Simon C, Swain J, Treff N, Ubaldi F, Vassena R, Vermeesch JR, Verpoest W, Wells D, Geraedts J. The why, the how and the when of PGS 2.0: current practices and expert opinions of fertility specialists, molecular biologists, and embryologists. Mol Hum Reprod. 2016 08; 22(8):845-57. PMID: 27256483.
      Citations: 23     Fields:    Translation:Humans
    47. Meldrum DR, Casper RF, Diez-Juan A, Simon C, Domar AD, Frydman R. Aging and the environment affect gamete and embryo potential: can we intervene? Fertil Steril. 2016 Mar; 105(3):548-559. PMID: 26812244.
      Citations: 28     Fields:    Translation:AnimalsCells
    48. Simon C, Sakkas D, Gardner DK, Critchley HO. Biomarkers in reproductive medicine: the quest for new answers. Hum Reprod Update. 2015 Nov-Dec; 21(6):695-7. PMID: 26386470.
      Citations: 5     Fields:    
    49. Martin J, Yi Y, Alberola T, Rodríguez-Iglesias B, Jiménez-Almazán J, Li Q, Du H, Alama P, Ruiz A, Bosch E, Garrido N, Simon C. Comprehensive carrier genetic test using next-generation deoxyribonucleic acid sequencing in infertile couples wishing to conceive through assisted reproductive technology. Fertil Steril. 2015 Nov; 104(5):1286-93. PMID: 26354092.
      Citations: 15     Fields:    Translation:Humans
    50. Vera-Rodriguez M, Chavez SL, Rubio C, Reijo Pera RA, Simon C. Prediction model for aneuploidy in early human embryo development revealed by single-cell analysis. Nat Commun. 2015 Jul 07; 6:7601. PMID: 26151134.
      Citations: 28     Fields:    Translation:Humans
    51. Miravet-Valenciano JA, Rincon-Bertolin A, Vilella F, Simon C. Understanding and improving endometrial receptivity. Curr Opin Obstet Gynecol. 2015 Jun; 27(3):187-92. PMID: 25827647.
      Citations: 27     Fields:    Translation:Humans
    52. Aleixandre-Benavent R, Simon C, Fauser BC. Trends in clinical reproductive medicine research: 10 years of growth. Fertil Steril. 2015 Jul; 104(1):131-7.e5. PMID: 25936232.
      Citations: 5     Fields:    Translation:Humans
    53. Thouas GA, Dominguez F, Green MP, Vilella F, Simon C, Gardner DK. Soluble ligands and their receptors in human embryo development and implantation. Endocr Rev. 2015 Feb; 36(1):92-130. PMID: 25548832.
      Citations: 22     Fields:    Translation:Humans
    54. Medrano JV, Simon C, Pera RR. Human germ cell differentiation from pluripotent embryonic stem cells and induced pluripotent stem cells. Methods Mol Biol. 2014; 1154:563-78. PMID: 24782029.
      Citations:    Fields:    Translation:HumansCells
    55. Paule S, Aljofan M, Simon C, Rombauts LJ, Nie G. Cleavage of endometrial a-integrins into their functional forms is mediated by proprotein convertase 5/6. Hum Reprod. 2012 Sep; 27(9):2766-74. PMID: 22740495.
      Citations: 8     Fields:    Translation:HumansCells
    56. Garrido-Gómez T, Dominguez F, Quiñonero A, Estella C, Vilella F, Pellicer A, Simon C. Annexin A2 is critical for embryo adhesiveness to the human endometrium by RhoA activation through F-actin regulation. FASEB J. 2012 Sep; 26(9):3715-27. PMID: 22645245.
      Citations: 18     Fields:    Translation:HumansCells
    57. Medrano JV, Ramathal C, Nguyen HN, Simon C, Reijo Pera RA. Divergent RNA-binding proteins, DAZL and VASA, induce meiotic progression in human germ cells derived in vitro. Stem Cells. 2012 Mar; 30(3):441-51. PMID: 22162380.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    58. Heng S, Cervero A, Simon C, Stephens AN, Li Y, Zhang J, Paule S, Rainczuk A, Singh H, Quinonero A, Tapia A, Velasquez L, Salamonsen L, Rombauts LJ, Nie G. Proprotein convertase 5/6 is critical for embryo implantation in women: regulating receptivity by cleaving EBP50, modulating ezrin binding, and membrane-cytoskeletal interactions. Endocrinology. 2011 Dec; 152(12):5041-52. PMID: 21971156.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    59. Panula S, Medrano JV, Kee K, Bergström R, Nguyen HN, Byers B, Wilson KD, Wu JC, Simon C, Hovatta O, Reijo Pera RA. Human germ cell differentiation from fetal- and adult-derived induced pluripotent stem cells. Hum Mol Genet. 2011 Feb 15; 20(4):752-62. PMID: 21131292.
      Citations: 83     Fields:    Translation:HumansCells
    60. Ensenat-Waser R, Pellicer A, Simon C. Reprogrammed induced pluripotent stem cells: how suitable could they be in reproductive medicine? Fertil Steril. 2009 Apr; 91(4):971-4. PMID: 19200985.
      Citations: 3     Fields:    Translation:HumansCells
    61. Busso CE, Melo MA, Fernandez M, Pellicer A, Simon C. Implantation in IVF. Int Surg. 2006 Sep-Oct; 91(5 Suppl):S63-76. PMID: 17436606.
      Citations: 2     Fields:    Translation:Humans
    62. Simon C, Domínguez F, Valbuena D, Pellicer A. The role of estrogen in uterine receptivity and blastocyst implantation. Trends Endocrinol Metab. 2003 Jul; 14(5):197-9. PMID: 12826321.
      Citations: 13     Fields:    Translation:HumansAnimals
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