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IONELA IACOBAS

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Hem-Onc Vasc Anomalies
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    2019Early-Career Faculty Award for Excellence in Patient Care, Baylor College of Medicine
    2019 - 20202020 Top downloaded paper, Pediatric Blood and Cancer. Wiley Publishers

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    Dr. Ionela Iacobas is the medical director of the Texas Children's Hospital Vascular Anomalies Center. Her main interest is to offer children and young adults with vascular anomalies state-of-the-art medical management in a comprehensive approach. Ranging from venous or lymphatic malformations to metastatic vascular tumors, the Vascular Anomalies Center uses anticoagulants (like low molecular weight heparin), immunosupressants (like sirolimus), chemotherapy, etc. to treat a large variety of vascular anomalies.
    Dr. Iacobas believes that children with vascular tumors and malformations need more than just invasive procedures and medications, so her team involves a multidisciplinary approach and the major supportive services (including physical therapy, social work, child life, psychology, pain management, orthotics - compression garments, support groups, etc).
    As education and research in the vascular anomalies field are essential for best patient care, Dr. Iacobas is very active at the national level as the Chair of the Vascular Anomalies Special Interest Group of ASPHO, where she and her team developed educational resources and a curriculum for hematology-oncology physicians who are interested in vascular anomalies.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Desai SB, Sun RC, Johnson BL, Rialon KL, Iacobas I, Kukreja KU, Schady DA, Phung T, Sanvitha S, Naik-Mathuria BJ. Renal Lymphangiectasia in a Pediatric Patient. Lymphat Res Biol. 2020 Jun 24. PMID: 32589505.
      View in: PubMed
    2. Knadler JJ, Lawrence E, Iacobas I, Justino H, Sheth S. Combination percutaneous and medical management of cardiac rhabdomyomas obstructing tricuspid valve inflow: Case report. J Neonatal Perinatal Med. 2020 Apr 23. PMID: 32333554.
      View in: PubMed
    3. Smith RJ, Metry D, Deardorff MA, Heller E, Grand KL, Iacobas I, Rubin AI, Phung TL, Lopez-Terrada D, Steicher J, Cahill AM, Low D, Treat JR. Segmental congenital hemangiomas: Three cases of a rare entity. Pediatr Dermatol. 2020 May; 37(3):548-553. PMID: 32255239.
      View in: PubMed
    4. Gurunathan A, Ricci K, Iacobas I, Rednam SP, Wusik K, Fei L, Hammilll AM. Impact of vascular anomalies on the PTEN phenotype in children and young adults. Pediatr Blood Cancer. 2020 06; 67(6):e28258. PMID: 32196895.
      View in: PubMed
    5. Cohen A, Owolabi FS, Dowdell-Smith CP, Laufman J, Iacobas I, Bass L, Foradori D. Weakness, Anemia, and Neutropenia in a 9-Year-Old Girl With Influenza. Pediatrics. 2020 04; 145(4). PMID: 32144121.
      View in: PubMed
    6. Iacobas I, Adams DM, Pimpalwar S, Phung T, Blei F, Burrows P, Lopez-Gutierrez JC, Levine MA, Trenor CC. Multidisciplinary guidelines for initial evaluation of complicated lymphatic anomalies-expert opinion consensus. Pediatr Blood Cancer. 2020 01; 67(1):e28036. PMID: 31617676.
      View in: PubMed
    7. Maynard K, LoPresti M, Iacobas I, Kan P, Lam S. Antiangiogenic agent as a novel treatment for pediatric intracranial arteriovenous malformations: case report. J Neurosurg Pediatr. 2019 Oct 04; 1-7. PMID: 31585413.
      View in: PubMed
    8. Sinton JW, Iacobas I, Cleveland H, Pimpalwar S. Case Report of Accelerated Idioventricular Rhythm in the Interventional Radiology Suite: A Sticky Situation. A A Pract. 2019 Apr 15; 12(8):273-276. PMID: 30371525.
      View in: PubMed
    9. Cohen CT, Bergstrom KL, Xiao R, Elghetany MT, Iacobas I, Sasa G. First case of neutropenia and thrombocytopenia in the setting of cerebral cavernous malformation 3. Int J Hematol. 2019 Jul; 110(1):95-101. PMID: 30904992.
      View in: PubMed
    10. Iacobas I, Phung TL, Adams DM, Trenor CC, Blei F, Fishman DS, Hammill A, Masand PM, Fishman SJ. Guidance Document for Hepatic Hemangioma (Infantile and Congenital) Evaluation and Monitoring. J Pediatr. 2018 12; 203:294-300.e2. PMID: 30244993.
      View in: PubMed
    11. Pimpalwar S, Yoo R, Chau A, Ashton D, Margolin J, Iacobas I. Temporal Evolution and Management of Fast Flow Vascular Anomalies in PTEN Hamartoma Tumor Syndrome. Int J Angiol. 2018 Sep; 27(3):158-164. PMID: 30154635.
      View in: PubMed
    12. Sheena Pimpalwar, Raphael Yoo, Alex Chau, Daniel Ashton, Judith Margolin, Ionela Iacobas. Temporal Evolution and Management of Fast Flow Vascular Anomalies in PTEN Hamartoma Tumor Syndrome. International Journal of Angiology. 2018; eFirst(2).
    13. Klein M, Chang AK, Vasudevan SA, Blatt J, Iacobas I, Lee S. Clinically significant ascites as an indication for resection of rapidly involuting congenital hepatic hemangiomas. Pediatr Blood Cancer. 2018 08; 65(8):e27222. PMID: 29741223.
      View in: PubMed
    14. Pimpalwar S, Pereira K, Margolin J, Iacobas I, Phan-Tran H, Pimpalwar A. Percutaneous Management of Peritoneovenous Shunt Malfunction in Children. J Vasc Interv Radiol. 2018 03; 29(3):433-435. PMID: 29455881.
      View in: PubMed
    15. Pimpalwar A, Iacobas I, Margolin J, Phan-Tran H, Pimpalwar S. Innovative Use of Denver Shunt in a Child with Generalized Lymphatic Anomaly. J Laparoendosc Adv Surg Tech A. 2017 Oct; 27(10):1091-1094. PMID: 28876997.
      View in: PubMed
    16. Grassia KL, Peterman CM, Iacobas I, Margolin JF, Bien E, Padhye B, Meyers RL, Adams DM. Clinical case series of pediatric hepatic angiosarcoma. Pediatr Blood Cancer. 2017 Nov; 64(11). PMID: 28521077.
      View in: PubMed
    17. Huho AN, Issaq N, Iacobas I, Elghetany TM, López-Terrada D, Fisher KE, Punia JN. A Rare Case of Pediatric Chronic Myelogenous Leukemia Presenting With Severe Thrombocytosis Without Leukocytosis. Pediatr Dev Pathol. 2018 Jan-Feb; 21(1):100-104. PMID: 29187020.
      View in: PubMed
    18. Mahajan P, Margolin J, Iacobas I. Kasabach-Merritt Phenomenon: Classic Presentation and Management Options. Clin Med Insights Blood Disord. 2017; 10:1179545X17699849. PMID: 28579853.
      View in: PubMed
    19. Iacobas I, Klepper L, Kelly J, Ferry T, Dellinger MT. Meeting Report for the 2016 Conference on GLA and Gorham-Stout Disease. IBMS BoneKEy. 2016; 847(13):1-3.
    20. Huho AN, Issaq N, Iacobas I, Elghetany MT, Lopez-Terrada D, Fisher K, Punia JN. A Rare Case of Pediatric Chronic Myelogenous Leukemia Presenting with Severe Thrombocytosis without Leukocytosis. Pediatr Dev Pathol. 2016 Jul 25. PMID: 27454200.
      View in: PubMed
    21. Iacobas I, Simon ML, Amir T, Gribbin CE, McPartland TG, Kaufman MR, Calderwood S, Nosher JL. Decreased vascularization of retroperitoneal kaposiform hemangioendothelioma induced by treatment with sirolimus explains relief of symptoms. Clin Imaging. 2015 May-Jun; 39(3):529-32. PMID: 25662209.
      View in: PubMed
    22. Sait S, Zaghloul N, Patel A, Shah T, Iacobas I, Calderwood S. Transfusion related iron overload in pediatric oncology patients treated at a tertiary care centre and treatment with chelation therapy. Pediatr Blood Cancer. 2014 Dec; 61(12):2319-20. PMID: 25154390.
      View in: PubMed
    23. Drolet BA, Trenor CC, Brandão LR, Chiu YE, Chun RH, Dasgupta R, Garzon MC, Hammill AM, Johnson CM, Tlougan B, Blei F, David M, Elluru R, Frieden IJ, Friedlander SF, Iacobas I, Jensen JN, King DM, Lee MT, Nelson S, Patel M, Pope E, Powell J, Seefeldt M, Siegel DH, Kelly M, Adams DM. Consensus-derived practice standards plan for complicated Kaposiform hemangioendothelioma. J Pediatr. 2013 Jul; 163(1):285-91. PMID: 23796341.
      View in: PubMed
    24. Iacobas I, Burrows PE. Chapter: Role of PTEN in Vascular Organization and Anomalies. PTEN: Structure, Mechanisms-of-Action, Role in Cell Signaling and Regulation. 2013; 211-233.
    25. Iacobas I, Burrows PE, Adams DM, Sutton VR, Hollier LH, Chintagumpala MM. Oral rapamycin in the treatment of patients with hamartoma syndromes and PTEN mutation. Pediatr Blood Cancer. 2011 Aug; 57(2):321-3. PMID: 21360661.
      View in: PubMed
    26. Iacobas I, Burrows PE, Frieden IJ, Liang MG, Mulliken JB, Mancini AJ, Kramer D, Paller AS, Silverman R, Wagner AM, Metry DW. LUMBAR: association between cutaneous infantile hemangiomas of the lower body and regional congenital anomalies. J Pediatr. 2010 Nov; 157(5):795-801.e1-7. PMID: 20598318.
      View in: PubMed
    27. Iacobas I, Vats A, Hirschi KK. Vascular potential of human pluripotent stem cells. Arterioscler Thromb Vasc Biol. 2010 Jun; 30(6):1110-7. PMID: 20453170.
      View in: PubMed
    28. Duffy HS, Iacobas I, Hotchkiss K, Hirst-Jensen BJ, Bosco A, Dandachi N, Dermietzel R, Sorgen PL, Spray DC. The gap junction protein connexin32 interacts with the Src homology 3/hook domain of discs large homolog 1. J Biol Chem. 2007 Mar 30; 282(13):9789-96. PMID: 17284442.
      View in: PubMed
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