NIKOLAOS DIAKOS

TitleClinical Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address6620 Main Street
Houston, 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Diakos NA, Swain L, Bhave S, Qiao X, Libermann T, Haywood J, Goel S, Annamalai S, Esposito M, Chweich H, Faugno A, Kapur NK. Circulating Proteome Analysis Identifies Reduced Inflammation After Initiation of Hemodynamic Support with Either Veno-Arterial Extracorporeal Membrane Oxygenation or Impella in Patients with Cardiogenic Shock. J Cardiovasc Transl Res. 2024 Feb 26. PMID: 38409476.
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    2. Alvarez Villela M, Liu S, Yin M, Esposito ML, Aghili N, Mustehsan MH, Larson I, Diakos NA, Kapur NK. Interventional Heart Failure: Current State of the Field. J Card Fail. 2024 Feb; 30(2):399-403. PMID: 37884169.
      Citations:    Fields:    Translation:Humans
    3. Balachandran IC, Segar MW, Diakos NA, Rogers JG. Conditional Survival After HeartMate 3 Implantation: An Analysis of the MOMENTUM 3 Trial. J Card Fail. 2023 09; 29(9):1329-1331. PMID: 37343814.
      Citations:    Fields:    Translation:Humans
    4. Diakos NA, Thayer K, Swain L, Goud M, Jain P, Kapur NK. Correction to: Systemic Inflammatory Burden Correlates with Severity and Predicts Outcomes in Patients with Cardiogenic Shock Supported by a Percutaneous Mechanical Assist Device. J Cardiovasc Transl Res. 2023 Jun; 16(3):754. PMID: 36417125; PMCID: PMC10320782.
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    5. Diakos NA. Management of Cardiogenic Shock: Present and Future. Tex Heart Inst J. 2023 05 01; 50(3). PMID: 37313619; PMCID: PMC10353273.
      Citations:    Fields:    Translation:Humans
    6. Gatsiou A, Tual-Chalot S, Napoli M, Ortega-Gomez A, Regen T, Badolia R, Cesarini V, Garcia-Gonzalez C, Chevre R, Ciliberti G, Silvestre-Roig C, Martini M, Hoffmann J, Hamouche R, Visker JR, Diakos N, Wietelmann A, Silvestris DA, Georgiopoulos G, Moshfegh A, Schneider A, Chen W, Guenther S, Backs J, Kwak S, Selzman CH, Stamatelopoulos K, Rose-John S, Trautwein C, Spyridopoulos I, Braun T, Waisman A, Gallo A, Drakos SG, Dimmeler S, Sperandio M, Soehnlein O, Stellos K. The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. Immunity. 2023 05 09; 56(5):979-997.e11. PMID: 37100060.
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    7. Diakos NA, Taleb I, Kyriakopoulos CP, Shah KS, Javan H, Richins TJ, Yin MY, Yen CG, Dranow E, Bonios MJ, Alharethi R, Koliopoulou AG, Taleb M, Fang JC, Selzman CH, Stellos K, Drakos SG. Circulating and Myocardial Cytokines Predict Cardiac Structural and Functional Improvement in Patients With Heart Failure Undergoing Mechanical Circulatory Support. J Am Heart Assoc. 2021 10 19; 10(20):e020238. PMID: 34595931; PMCID: PMC8751895.
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    8. Slomovich S, Oh KT, Diakos NA, Restaino SW, Clerkin KJ, Latif F, Miyauchi JT, Lee A, Sayer GT, Uriel N. A Rare Case of Disseminated Tuberculosis and Hematological Malignancy in a Heart Transplant Recipient. Transplant Proc. 2021 Oct; 53(8):2626-2629. PMID: 34399971.
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    9. Kampaktsis PN, Tzani A, Doulamis IP, Moustakidis S, Drosou A, Diakos N, Drakos SG, Briasoulis A. State-of-the-art machine learning algorithms for the prediction of outcomes after contemporary heart transplantation: Results from the UNOS database. Clin Transplant. 2021 08; 35(8):e14388. PMID: 34155697.
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    10. Larson A, Libermann TA, Bowditch H, Das G, Diakos N, Huggins GS, Rastegar H, Chen FY, Rowin EJ, Maron MS, Chin MT. Plasma Proteomic Profiling in Hypertrophic Cardiomyopathy Patients before and after Surgical Myectomy Reveals Post-Procedural Reduction in Systemic Inflammation. Int J Mol Sci. 2021 Mar 01; 22(5). PMID: 33804404; PMCID: PMC7957543.
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    11. Cluntun AA, Badolia R, Lettlova S, Parnell KM, Shankar TS, Diakos NA, Olson KA, Taleb I, Tatum SM, Berg JA, Cunningham CN, Van Ry T, Bott AJ, Krokidi AT, Fogarty S, Skedros S, Swiatek WI, Yu X, Luo B, Merx S, Navankasattusas S, Cox JE, Ducker GS, Holland WL, McKellar SH, Rutter J, Drakos SG. The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure. Cell Metab. 2021 03 02; 33(3):629-648.e10. PMID: 33333007; PMCID: PMC7933116.
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    12. Koliopoulou AG, Bonios MJ, Diakos NA, Drakos SG. Biventricular failure and total artificial heart: Old and new solutions for a vexing problem. Hellenic J Cardiol. 2020 Nov-Dec; 61(6):413-414. PMID: 33771328.
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    13. Diakos NA, Thayer K, Swain L, Goud M, Jain P, Kapur NK. Systemic Inflammatory Burden Correlates with Severity and Predicts Outcomes in Patients with Cardiogenic Shock Supported by a Percutaneous Mechanical Assist Device. J Cardiovasc Transl Res. 2021 06; 14(3):476-483. PMID: 33078375; PMCID: PMC9643251.
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    14. Riehle C, Weatherford ET, Wende AR, Jaishy BP, Seei AW, McCarty NS, Rech M, Shi Q, Reddy GR, Kutschke WJ, Oliveira K, Pires KM, Anderson JC, Diakos NA, Weiss RM, White MF, Drakos SG, Xiang YK, Abel ED. Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling. JCI Insight. 2020 03 26; 5(6). PMID: 32213702; PMCID: PMC7213803.
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    15. Symons JD, Deeter L, Deeter N, Bonn T, Cho JM, Ferrin P, McCreath L, Diakos NA, Taleb I, Alharethi R, McKellar S, Wever-Pinzon O, Navankasattusas S, Selzman CH, Fang JC, Drakos SG. Effect of Continuous-Flow Left Ventricular Assist Device Support on Coronary Artery Endothelial Function in Ischemic and Nonischemic Cardiomyopathy. Circ Heart Fail. 2019 08; 12(8):e006085. PMID: 31422672.
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    16. Pepin ME, Ha CM, Crossman DK, Litovsky SH, Varambally S, Barchue JP, Pamboukian SV, Diakos NA, Drakos SG, Pogwizd SM, Wende AR. Genome-wide DNA methylation encodes cardiac transcriptional reprogramming in human ischemic heart failure. Lab Invest. 2019 03; 99(3):371-386. PMID: 30089854; PMCID: PMC6515060.
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    17. Catino AB, Ferrin P, Wever-Pinzon J, Horne BD, Wever-Pinzon O, Kfoury AG, McCreath L, Diakos NA, McKellar S, Koliopoulou A, Bonios MJ, Al-Sarie M, Taleb I, Dranow E, Fang JC, Drakos SG. Clinical and histopathological effects of heart failure drug therapy in advanced heart failure patients on chronic mechanical circulatory support. Eur J Heart Fail. 2018 01; 20(1):164-174. PMID: 29094485.
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    18. Diakos NA, Passi S, Taleb I, Kfoury AG, Drakos SG. Regional myocardial structural characteristics in ischemic and non-ischemic cardiomyopathy: Left ventricle versus right and apex versus base. J Heart Lung Transplant. 2018 01; 37(1):166-169. PMID: 28890255.
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    19. Seidel T, Navankasattusas S, Ahmad A, Diakos NA, Xu WD, Tristani-Firouzi M, Bonios MJ, Taleb I, Li DY, Selzman CH, Drakos SG, Sachse FB. Sheet-Like Remodeling of the Transverse Tubular System in Human Heart Failure Impairs Excitation-Contraction Coupling and Functional Recovery by Mechanical Unloading. Circulation. 2017 Apr 25; 135(17):1632-1645. PMID: 28073805; PMCID: PMC5404964.
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    20. Diakos NA, Navankasattusas S, Abel ED, Rutter J, McCreath L, Ferrin P, McKellar SH, Miller DV, Park SY, Richardson RS, Deberardinis R, Cox JE, Kfoury AG, Selzman CH, Stehlik J, Fang JC, Li DY, Drakos SG. Evidence of Glycolysis Up-Regulation and Pyruvate Mitochondrial Oxidation Mismatch During Mechanical Unloading of the Failing Human Heart: Implications for Cardiac Reloading and Conditioning. JACC Basic Transl Sci. 2016 Oct; 1(6):432-444. PMID: 28497127; PMCID: PMC5422992.
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    21. Wever-Pinzon J, Selzman CH, Stoddard G, Wever-Pinzon O, Catino A, Kfoury AG, Diakos NA, Reid BB, McKellar S, Bonios M, Koliopoulou A, Budge D, Kelkhoff A, Stehlik J, Fang JC, Drakos SG. Impact of Ischemic Heart Failure Etiology on Cardiac Recovery During Mechanical?Unloading. J Am Coll Cardiol. 2016 10 18; 68(16):1741-1752. PMID: 27737740.
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    22. Zagorianou A, Marougkas M, Drakos SG, Diakos N, Konstantopoulos P, Perrea DN, Anastasiou-Nana M, Malliaras K. The effect of long-term amiodarone administration on myocardial fibrosis and evolution of left ventricular remodeling in a porcine model of ischemic cardiomyopathy. Springerplus. 2016; 5(1):1568. PMID: 27652141; PMCID: PMC5023647.
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    23. Park SY, Trinity JD, Gifford JR, Diakos NA, McCreath L, Drakos S, Richardson RS. Mitochondrial function in heart failure: The impact of ischemic and non-ischemic etiology. Int J Cardiol. 2016 Oct 01; 220:711-7. PMID: 27394972; PMCID: PMC7601846.
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    24. Al-Sarie M, Rauf A, Kfoury AG, Catino A, Wever-Pinzon J, Bonios M, Horne BD, Diakos NA, Wever-Pinzon O, McKellar SH, Kelkhoff A, McCreath L, Fang J, Stehlik J, Selzman CH, Drakos SG. Myocardial Structural and Functional Response After Long-Term Mechanical Unloading With Continuous Flow Left?Ventricular Assist Device: Axial Versus Centrifugal Flow. JACC Heart Fail. 2016 07; 4(7):570-576. PMID: 27179831.
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    25. Pantsios C, Kapelios C, Vakrou S, Diakos N, Pozios I, Kontogiannis C, Nanas J, Malliaras K. Effect of Elevated Reperfusion Pressure on "No Reflow" Area and Infarct Size in a Porcine Model of Ischemia-Reperfusion. J Cardiovasc Pharmacol Ther. 2016 07; 21(4):405-11. PMID: 26589289.
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    26. Diakos NA, Selzman CH, Stehlik J, Sachse FB, Kfoury AG, Koliopoulou A, McKellar S, Fang JC, Li DY, Drakos SG. Reply: does size matter? In search of a physiological definition of myocardial atrophy. J Am Coll Cardiol. 2015 May 19; 65(19):2156-7. PMID: 25975488.
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    27. Diakos NA, Pozios I, Katsaros L, Vakrou S, Sventzouri S, Michelinakis N, Tseliou E, Bonios M, Malliaras K, Papalois A, Anastasiou-Nana M, Terrovitis JV. Afterload-induced left ventricular diastolic dysfunction during myocardial ischaemia and reperfusion. Exp Physiol. 2015 Mar; 100(3):288-301. PMID: 25523362.
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    28. Terrovitis JV, Ntalianis A, Kapelios CJ, Vakrou S, Diakos N, Katsaros L, Tsamatsoulis M, Kaldara E, Charitos C, Nanas JN. Dabigatran etexilate as second-line therapy in patients with a left ventricular assist device. Hellenic J Cardiol. 2015 Jan-Feb; 56(1):20-5. PMID: 25701968.
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    29. Malliaras K, Charitos E, Diakos N, Pozios I, Papalois A, Terrovitis J, Nanas J. Effects of intra-aortic balloon pump counterpulsation on left ventricular mechanoenergetics in a porcine model of acute ischemic heart failure. J Cardiovasc Transl Res. 2014 Dec; 7(9):810-20. PMID: 25376149.
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    30. Diakos NA, Selzman CH, Sachse FB, Stehlik J, Kfoury AG, Wever-Pinzon O, Catino A, Alharethi R, Reid BB, Miller DV, Salama M, Zaitsev AV, Shibayama J, Li H, Fang JC, Li DY, Drakos SG. Myocardial atrophy and chronic mechanical unloading of the failing human heart: implications for cardiac assist device-induced myocardial recovery. J Am Coll Cardiol. 2014 Oct 14; 64(15):1602-12. PMID: 25301465.
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    31. Abdullah OM, Drakos SG, Diakos NA, Wever-Pinzon O, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Brunisholz K, Verma DR, Myrick C, Sachse FB, Li DY, Hsu EW. Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological validation. NMR Biomed. 2014 Nov; 27(11):1378-86. PMID: 25200106; PMCID: PMC4215542.
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    32. Park SY, Gifford JR, Andtbacka RH, Trinity JD, Hyngstrom JR, Garten RS, Diakos NA, Ives SJ, Dela F, Larsen S, Drakos S, Richardson RS. Cardiac, skeletal, and smooth muscle mitochondrial respiration: are all mitochondria created equal? Am J Physiol Heart Circ Physiol. 2014 Aug 01; 307(3):H346-52. PMID: 24906913; PMCID: PMC4121645.
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    33. Drakos SG, Wever-Pinzon O, Selzman CH, Gilbert EM, Alharethi R, Reid BB, Saidi A, Diakos NA, Stoker S, Davis ES, Movsesian M, Li DY, Stehlik J, Kfoury AG, UCAR (Utah Cardiac Recovery Program) Investigators. Magnitude and time course of changes induced by continuous-flow left ventricular assist device unloading in chronic heart failure: insights into cardiac recovery. J Am Coll Cardiol. 2013 May 14; 61(19):1985-94. PMID: 23500219; PMCID: PMC3819804.
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    34. Pierrakos CN, Tsolakis EJ, Pozios IA, Diakos N, Charitos E, Malliaras K, Bonios MJ, Lazaris N, Papazoglou P, Venetsanakos J, Papalois A, Terrovitis JV, Nanas JN. Effects of L-NAME on coronary blood flow, infarct size and the extent of the no-reflow phenomenon. Int J Cardiol. 2013 Sep 10; 167(6):3000-5. PMID: 23022088.
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    35. Terrovitis J, Zotos P, Kaldara E, Diakos N, Tseliou E, Vakrou S, Kapelios C, Chalazonitis A, Nanas S, Toumanidis S, Kontoyannis D, Karga E, Nanas J. Bone mass loss in chronic heart failure is associated with secondary hyperparathyroidism and has prognostic significance. Eur J Heart Fail. 2012 Mar; 14(3):326-32. PMID: 22286155.
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    36. Dimopoulos S, Diakos N, Tseliou E, Tasoulis A, Mpouchla A, Manetos C, Katsaros L, Drakos S, Terrovitis J, Nanas S. Chronotropic incompetence and abnormal heart rate recovery early after left ventricular assist device implantation. Pacing Clin Electrophysiol. 2011 Dec; 34(12):1607-14. PMID: 21950763.
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    37. Chan AC, Drakos SG, Ruiz OE, Smith AC, Gibson CC, Ling J, Passi SF, Stratman AN, Sacharidou A, Revelo MP, Grossmann AH, Diakos NA, Davis GE, Metzstein MM, Whitehead KJ, Li DY. Mutations in 2 distinct genetic pathways result in cerebral cavernous malformations in mice. J Clin Invest. 2011 May; 121(5):1871-81. PMID: 21490399; PMCID: PMC3083782.
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    38. Drakos SG, Terrovitis JV, Nanas JN, Charitos EI, Ntalianis AS, Malliaras KG, Diakos N, Koudoumas D, Theodoropoulos S, Yacoub MH, Anastasiou-Nana MI. Reverse electrophysiologic remodeling after cardiac mechanical unloading for end-stage nonischemic cardiomyopathy. Ann Thorac Surg. 2011 Mar; 91(3):764-9. PMID: 21352994.
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    39. Bouchla A, Karatzanos E, Dimopoulos S, Tasoulis A, Agapitou V, Diakos N, Tseliou E, Terrovitis J, Nanas S. The addition of strength training to aerobic interval training: effects on muscle strength and body composition in CHF patients. J Cardiopulm Rehabil Prev. 2011 Jan-Feb; 31(1):47-51. PMID: 20562711.
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    40. Drakos SG, Athanasoulis T, Malliaras KG, Terrovitis JV, Diakos N, Koudoumas D, Ntalianis AS, Theodoropoulos SP, Yacoub MH, Nanas JN. Myocardial sympathetic innervation and long-term left ventricular mechanical unloading. JACC Cardiovasc Imaging. 2010 Jan; 3(1):64-70. PMID: 20129533.
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