CHARLES WYKOFF

TitleClinical Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Ophthalmology
Address6560 Fannin, Suite 750
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mahmoudi A, Lindenberg S, Corradetti G, Emamverdi M, Oncel D, Oncel D, Baek J, Farahani A, Almidani L, He Y, Abbasgholizadeh R, Saju SM, Lee WK, Wykoff CC, Sarraf D, Freund KB, Sadda SR. Predictive Factors Influencing the Evolution of Acquired Vitelliform Lesions in Intermediate Age-related Macular Degeneration Eyes. Ophthalmol Retina. 2024 Apr 08. PMID: 38599379.
      Citations:    
    2. Cao JA, Al-Khersan H, Chaudhary V, Wykoff CC. Correction: Retinal non-perfusion: recognizing and defining what is important. Eye (Lond). 2024 Mar 28. PMID: 38548947.
      Citations:    Fields:    
    3. Campochiaro PA, Avery R, Brown DM, Heier JS, Ho AC, Huddleston SM, Jaffe GJ, Khanani AM, Pakola S, Pieramici DJ, Wykoff CC, Van Everen S. Gene therapy for neovascular age-related macular degeneration by subretinal delivery of RGX-314: a phase 1/2a dose-escalation study. Lancet. 2024 Mar 27. PMID: 38554726.
      Citations:    Fields:    
    4. Zarbin MA, MacCumber MW, Karcher H, Adiguzel E, Mayhook A, LaPrise A, Bilano VL, Igwe F, Ip MS, Wykoff CC. Real-World Safety Outcomes with Brolucizumab in Neovascular Age-Related Macular Degeneration: Findings from the IRIS? Registry. Ophthalmol Ther. 2024 Mar 23. PMID: 38520643.
      Citations:    
    5. Brown DM, Boyer DS, Do DV, Wykoff CC, Sakamoto T, Win P, Joshi S, Salehi-Had H, Seres A, Berliner AJ, Leal S, Vitti R, Chu KW, Reed K, Rao R, Cheng Y, Sun W, Voronca D, Bhore R, Schmidt-Ott U, Schmelter T, Schulze A, Zhang X, Hirshberg B, Yancopoulos GD, Sivaprasad S, PHOTON Investigators. Intravitreal aflibercept 8 mg in diabetic macular oedema (PHOTON): 48-week results from a randomised, double-masked, non-inferiority, phase 2/3 trial. Lancet. 2024 Mar 23; 403(10432):1153-1163. PMID: 38461843.
      Citations:    Fields:    Translation:CTClinical Trials
    6. Wykoff CC, Avery RL, Barakat MR, Boyer DS, Brown DM, Brucker AJ, Cunningham ET, Heier JS, Holekamp NM, Kaiser PK, Khanani AM, Kim JE, Demirci H, Regillo CD, Yiu G, Ciulla TA. Suprachoroidal Space Injection Technique: Expert Panel Guidance. Retina. 2024 Mar 05. PMID: 38451179.
      Citations:    Fields:    
    7. Cao JA, Al-Khersan H, Chaudhary V, Wykoff CC. Retinal non-perfusion: recognizing and defining what is important. Eye (Lond). 2024 Mar 04. PMID: 38438795.
      Citations:    Fields:    
    8. Mahmoudi A, Manafi N, Corradetti G, Gupta Nittala M, Emamverdi M, Trejo Corona S, Wykoff CC, Sarraf D, Sadda SR. Risk factors for development of hyper-reflective foci overlying drusen in eyes with intermediate age-related macular degeneration. Br J Ophthalmol. 2024 Feb 07. PMID: 38325906.
      Citations:    Fields:    
    9. Zeraatkar D, Pitre T, Phillips M, Steel DH, Wykoff CC, Wong TY, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. The ophthalmologist's guide to evaluating the certainty of evidence using the GRADE approach. Eye (Lond). 2024 Feb 05. PMID: 38316973.
      Citations:    Fields:    
    10. Manafi N, Mahmoudi A, Emamverdi M, Corradetti G, Corona ST, Wykoff CC, Sadda SR. Topographic analysis of local OCT biomarkers which predict progression to atrophy in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2024 Feb 01. PMID: 38300334.
      Citations:    Fields:    
    11. Shah M, Albini T, Nguyen Q, Wykoff C, Barakat M, Kapik B, Ciulla TA, Khurana RN. Safety and Efficacy of CLS-TA by Anatomic Location of Inflammation: Results from the Phase 3 PEACHTREE Clinical Trial. Ocul Immunol Inflamm. 2024 Jan 09; 1-8. PMID: 38194432.
      Citations:    Fields:    
    12. Cao JA, Dubovy SR, Fan KC, Parvus MN, Fortun JA, Wykoff CC. Free-Floating Pigmented Vitreous Cysts: Clinical-Histopathologic Correlation. Ophthalmic Surg Lasers Imaging Retina. 2024 Jan; 55(1):55-58. PMID: 38189800.
      Citations:    Fields:    Translation:Humans
    13. Eter N, Murata T, Ruamviboonsuk P, Schlottmann PG, Seres AI, Sun X, Yoon YH, YOSEMITE and RHINE Investigators, Wong TY, Haskova Z, Asik K, Baumal CR, Csaky KG, Ives JA, Jaffe GJ, Korobelnik JF, Lin H, Silverman D, Tang Y, Wells JA, Wykoff CC. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials. Ophthalmology. 2023 Dec 28. PMID: 38158159.
      Citations:    Fields:    
    14. Khanani AM, Boyer DS, Wykoff CC, Regillo CD, Busbee BG, Pieramici D, Danzig CJ, Joondeph BC, Major JC, Turpcu A, Kiss S. Safety and efficacy of ixoberogene soroparvovec in neovascular age-related macular degeneration in the United States (OPTIC): a prospective, two-year, multicentre phase 1 study. EClinicalMedicine. 2024 Jan; 67:102394. PMID: 38152412; PMCID: PMC10751837.
      Citations: 1     
    15. Singh RP, Barakat MR, Ip MS, Wykoff CC, Eichenbaum DA, Joshi S, Warrow D, Sheth VS, Stefanickova J, Kim YS, He F, Cho GE, Wang Y, Emanuelli A. Efficacy and Safety of Brolucizumab for Diabetic Macular Edema: The KINGFISHER Randomized Clinical Trial. JAMA Ophthalmol. 2023 Dec 01; 141(12):1152-1160. PMID: 37971723.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    16. Patel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Correction: Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 Dec; 37(17):3705. PMID: 37237234; PMCID: PMC10686405.
      Citations: 1     Fields:    
    17. Garg A, Nanji K, Tai F, Phillips M, Zeraatkar D, Garg SJ, Sadda SR, Kaiser PK, Guymer RH, Sivaprasad S, Wykoff CC, Chaudhary V. The effect of complement C3 or C5 inhibition on geographic atrophy secondary to age-related macular degeneration: A living systematic review and meta-analysis. Surv Ophthalmol. 2023 Nov 24. PMID: 38008405.
      Citations: 1     Fields:    
    18. Avram O, Durmus B, Rakocz N, Corradetti G, An U, Nitalla MG, Rudas A, Wakatsuki Y, Hirabayashi K, Velaga S, Tiosano L, Corvi F, Verma A, Karamat A, Lindenberg S, Oncel D, Almidani L, Hull V, Fasih-Ahmad S, Esmaeilkhanian H, Wykoff CC, Rahmani E, Arnold CW, Zhou B, Zaitlen N, Gronau I, Sankararaman S, Chiang JN, Sadda SR, Halperin E. SLIViT: a general AI framework for clinical-feature diagnosis from limited 3D biomedical-imaging data. Res Sq. 2023 Nov 21. PMID: 38045283; PMCID: PMC10690310.
      Citations:    
    19. Wykoff CC, Garmo V, Tabano D, Menezes A, Kim E, Fevrier HB, LaPrise A, Leng T. Impact of Anti-VEGF Treatment and Patient Characteristics on Vision Outcomes in Neovascular Age-related Macular Degeneration: Up to 6-Year Analysis of the AAO IRIS? Registry. Ophthalmol Sci. 2024 Mar-Apr; 4(2):100421. PMID: 38187126; PMCID: PMC10767511.
      Citations:    
    20. Nanji K, Yu CW, Wong TY, Sivaprasad S, Steel DH, Wykoff CC, Chaudhary V. Evaluation of postoperative ophthalmology patient instructions from ChatGPT and Google Search. Can J Ophthalmol. 2024 Feb; 59(1):e69-e71. PMID: 37884271.
      Citations:    Fields:    Translation:Humans
    21. Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Mon?s J, Singh RP, Ribeiro R, Wykoff CC, OAKS and DERBY study investigators. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials. Lancet. 2023 10 21; 402(10411):1434-1448. PMID: 37865470.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    22. Patel SB, Heier JS, Chaudhary V, Wykoff CC. Treatment of geographic atrophy: an update on data related to pegcetacoplan. Curr Opin Ophthalmol. 2024 Jan 01; 35(1):64-72. PMID: 37815317.
      Citations: 1     Fields:    Translation:Humans
    23. Tai F, Nanji K, Garg A, Zeraatkar D, Phillips M, Steel DH, Garg SJ, Kaiser PK, Guymer RH, Sivaprasad S, Chaudhary V, Wykoff CC. Subthreshold Compared with Threshold Macular Photocoagulation for Diabetic Macular Edema: A Systematic Review and Meta-Analysis. Ophthalmol Retina. 2024 Mar; 8(3):223-233. PMID: 37805099.
      Citations:    Fields:    Translation:Humans
    24. Singh RP, Amoaku W, Bandello F, Chen FK, Holz FG, Kodjikian L, Ruiz-Moreno JM, Joshi P, Wykoff CC. Diagnosis and Management of Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Delphi Consensus Exercise. Ophthalmic Surg Lasers Imaging Retina. 2023 10; 54(10):589-598. PMID: 37847167.
      Citations: 1     Fields:    Translation:Humans
    25. Kalra G, Wykoff C, Martin A, Srivastava SK, Reese J, Ehlers JP. Longitudinal Quantitative Ultrawidefield Angiographic Features in Diabetic Retinopathy Treated with Aflibercept from the Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement Trial. Ophthalmol Retina. 2024 Feb; 8(2):116-125. PMID: 37696393; PMCID: PMC10872550.
      Citations:    Fields:    Translation:Humans
    26. Khanani AM, Patel SS, Staurenghi G, Tadayoni R, Danzig CJ, Eichenbaum DA, Hsu J, Wykoff CC, Heier JS, Lally DR, Mon?s J, Nielsen JS, Sheth VS, Kaiser PK, Clark J, Zhu L, Patel H, Tang J, Desai D, Jaffe GJ, GATHER2 trial investigators. Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial. Lancet. 2023 Oct 21; 402(10411):1449-1458. PMID: 37696275.
      Citations: 5     Fields:    
    27. Kokilepersaud K, Corona ST, Prabhushankar M, AlRegib G, Wykoff C. Clinically Labeled Contrastive Learning for OCT Biomarker Classification. IEEE J Biomed Health Inform. 2023 09; 27(9):4397-4408. PMID: 37216249.
      Citations:    Fields:    Translation:Humans
    28. Chen SN, Chou HD, Lai CC, Mahgoub MM, Matoba R, Morizane Y, Nehemy MB, Park JG, Adrean SD, Begaj T, Capone A, Charles S, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Mansoor M, Raphaelian PV, Regillo CD, Ruby AJ, Runner MM, Sneed SR, Sohn EH, Spirn MJ, Vander JF, Wakabayashi T, Wolfe JD, Wykoff CC, Yonekawa Y, Yoon YH, Mahmoud TH. Surgical Management of Full-Thickness Macular Holes in Macular Telangiectasia Type 2: A Global Multicenter Study. Ophthalmology. 2024 Jan; 131(1):66-77. PMID: 37661066.
      Citations:    Fields:    Translation:Humans
    29. Wykoff CC, Brown DM, Reed K, Berliner AJ, Gerstenblith AT, Breazna A, Abraham P, Fein JG, Chu KW, Clark WL, Leal S, Schmelter T, Hirshberg B, Yancopoulos GD, Vitti R, CANDELA Study Investigators. Effect of High-Dose Intravitreal Aflibercept, 8 mg, in Patients With Neovascular Age-Related Macular Degeneration: The Phase 2 CANDELA Randomized Clinical Trial. JAMA Ophthalmol. 2023 09 01; 141(9):834-842. PMID: 37535382.
      Citations: 5     Fields:    Translation:Humans
    30. Louis AM, Ali AM, Patel SB, Fan KC, Rahman EZ, Pearce WA, Trejo Corona S, Villanueva Boone C, Yu HJ, Wykoff CC. Impact of Prefilled Syringes and Masking on Postintravitreal Injection Endophthalmitis. J Vitreoretin Dis. 2023 Sep-Oct; 7(5):382-388. PMID: 37706081; PMCID: PMC10496810.
      Citations:    
    31. Salabati M, Huang C, Kamalipour A, Yu HJ, Mahmoudzadeh R, Jeng-Miller K, Chen E, Shah CP, Wykoff CC, Hsu J. Magnitude of Visual Acuity Change with ETDRS versus Snellen Testing in Clinical Trials: Implications for Clinic-Based Outcomes. Ophthalmol Sci. 2024 Mar-Apr; 4(2):100372. PMID: 37868803; PMCID: PMC10587620.
      Citations: 1     
    32. Wykoff CC, Garweg JG, Regillo C, Souied E, Wolf S, Dhoot DS, Agostini HT, Chang A, Laude A, Wachtlin J, Kovacic L, Wang L, Wang Y, Bouillaud E, Brown DM. KESTREL and KITE Phase 3 Studies: 100-Week Results With Brolucizumab in Patients With Diabetic Macular Edema. Am J Ophthalmol. 2024 Apr; 260:70-83. PMID: 37460036.
      Citations: 3     Fields:    Translation:Humans
    33. Yu CW, Nanji K, Hatamnejad A, Gemae M, Joarder I, Achunair A, Devji T, Phillips M, Zeraatkar D, Guymer RH, Chaudhary V, Steel DH, Sivaprasad S, Wykoff CC. Patient-Reported Outcome Measure Use in Guidelines Published by the American Academy of Ophthalmology: A Review. Ophthalmology. 2023 Nov; 130(11):1201-1211. PMID: 37429499.
      Citations:    Fields:    
    34. Grewal DS, Wykoff CC, D'Souza D, Jehl V, Alecu I, Jaffe GJ. Imaging Features of Retinal Vasculitis and/or Retinal Vascular Occlusion after Brolucizumab Treatment in the Postmarketing Setting. Ophthalmol Sci. 2024 Jan-Feb; 4(1):100361. PMID: 37869023; PMCID: PMC10587630.
      Citations:    
    35. Matsumoto H, Karcher H, Mayhook A, Oshagbemi OA, Zorina O, Wykoff CC, Barakat MR, Lozama A, Hassan TS, Khanani AM, Heier JS. RETINAL VASCULITIS OR VASCULAR OCCLUSION AFTER BROLUCIZUMAB FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Systematic Review of Real-World Evidence. Retina. 2023 07 01; 43(7):1051-1063. PMID: 36893438; PMCID: PMC10278563.
      Citations: 2     Fields:    Translation:Humans
    36. Hatamnejad A, Dadak R, Orr S, Wykoff C, Choudhry N. Systematic review of efficacy and meta-analysis of safety of ranibizumab biosimilars relative to reference ranibizumab anti-VEGF therapy for nAMD treatment. BMJ Open Ophthalmol. 2023 06; 8(1). PMID: 37493655; PMCID: PMC10277130.
      Citations: 1     Fields:    Translation:Humans
    37. Peng ET, Parvus MN, Yu HJ, Laswell SM, Pearce WA, Fan KC, Major JC, Brown DM, Wykoff CC, Patel SB. Risk Factors for the Development of Fellow Eye Horseshoe Retinal Tears Following Horseshoe Retinal Tear in the Presenting Eye. Ophthalmic Surg Lasers Imaging Retina. 2023 Jun; 54(6):338-345. PMID: 37352399.
      Citations:    Fields:    Translation:Humans
    38. Cao JA, Patel SB, Wong CW, Garcia D, Munoz J, Cone C, Zamora D, Reagan M, Nguyen TV, Pearce W, Fish RH, Brown DM, Chaudhary V, Wykoff CC, Fan KC. Demographic and Socioeconomic Factors in Prospective Retina-Focused Clinical Trial Screening and Enrollment. J Pers Med. 2023 May 23; 13(6). PMID: 37373869; PMCID: PMC10303745.
      Citations:    
    39. Callanan D, Khurana RN, Maturi RK, Patel S, Wykoff CC, Eichenbaum D, Khanani AM, Hassan T, Badger H, Mehta S, Le G, Attar M, Seal J, Li XY. Impact of Modifying Abicipar Manufacturing Process in Patients with Neovascular Age-Related Macular Degeneration: MAPLE Study Results. Clin Ophthalmol. 2023; 17:1367-1384. PMID: 37197577; PMCID: PMC10184835.
      Citations: 1     Translation:CTClinical Trials
    40. Rao AV, Shah AR, Nguyen VT, Pearce W, Wong TP, Brown DM, Wykoff CC, Patel SB. USE OF OPTICAL COHERENCE TOMOGRAPHY IN DETECTING RETINAL TEARS IN ACUTE, SYMPTOMATIC POSTERIOR VITREOUS DETACHMENT. Retina. 2023 05 01; 43(5):802-807. PMID: 36728866.
      Citations:    Fields:    Translation:Humans
    41. Phillips MR, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Correction to: The clinician's guide to p values, confidence intervals, and magnitude of effects. Eye (Lond). 2023 May; 37(7):1515. PMID: 35046555; PMCID: PMC10170072.
      Citations:    Fields:    
    42. Karcher H, Igwe F, Freitas R, MacCumber MW, Wykoff CC, Adiguzel E, Sinha SB, Vishwakarma S, LaPrise A, Ip MS, Zarbin MA. One-Year Brolucizumab Outcomes in Neovascular Age-Related Macular Degeneration from a Large United States Cohort in the IRIS? Registry. Ophthalmology. 2023 09; 130(9):937-946. PMID: 37086857.
      Citations: 1     Fields:    Translation:Humans
    43. Nanji K, Sarohia GS, Xie J, Patil NS, Phillips M, Zeraatkar D, Thabane L, Guymer RH, Kaiser PK, Sivaprasad S, Sadda SR, Wykoff CC, Chaudhary V. Anti-vascular endothelial growth factor therapy and retinal non-perfusion in diabetic retinopathy: A meta-analysis of randomised trials. Acta Ophthalmol. 2024 Feb; 102(1):e31-e41. PMID: 37042340.
      Citations:    Fields:    
    44. Chang Y, Wang L, Phillips MR, Wykoff CC, Garg SJ, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. What makes a good survey? Eye (Lond). 2023 Nov; 37(16):3299-3301. PMID: 37029303; PMCID: PMC10630307.
      Citations:    Fields:    
    45. Parvus MN, Trejo Corona S, Fan KC, Wykoff CC. Valsalva Retinopathy After Yoga in a Patient With No Clear Predisposing Condition. J Vitreoretin Dis. 2023 Jul-Aug; 7(4):337-339. PMID: 37927323; PMCID: PMC10621705.
      Citations:    
    46. Hattenbach LO, Abreu F, Arrisi P, Basu K, Danzig CJ, Guymer R, Haskova Z, Heier JS, Kotecha A, Liu Y, Loewenstein A, Seres A, Willis JR, Wykoff CC, Paris LP. BALATON and COMINO: Phase III Randomized Clinical Trials of Faricimab for Retinal Vein Occlusion: Study Design and Rationale. Ophthalmol Sci. 2023 Sep; 3(3):100302. PMID: 37810589; PMCID: PMC10556281.
      Citations: 3     
    47. Karcher H, Igwe F, Freitas R, MacCumber MW, Wykoff CC, Adiguzel E, Sinha SB, Vishwakarma S, LaPrise A, Ip MS, Zarbin MA. Factors Linked to Injection Interval Extension in Eyes with Wet Age-Related Macular Degeneration Switched to Brolucizumab. Ophthalmology. 2023 08; 130(8):795-803. PMID: 36990322.
      Citations:    Fields:    Translation:Humans
    48. Patel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 12; 37(17):3551-3557. PMID: 36964259; PMCID: PMC10686386.
      Citations: 2     Fields:    
    49. Kim K, Zeraatkar D, Pitre TS, Phillips M, Wykoff CC, Garg SJ, Guymer RH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Noninferiority randomised trials in ophthalmology. Eye (Lond). 2023 10; 37(15):3059-3060. PMID: 36869135; PMCID: PMC10564920.
      Citations:    Fields:    
    50. Regillo C, Berger B, Brooks L, Clark WL, Mittra R, Wykoff CC, Callaway NF, DeGraaf S, Ding HT, Fung AE, Gune S, Le Pogam S, Smith R, Willis JR, Barteselli G. Archway Phase 3 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration 2-Year Results. Ophthalmology. 2023 Jul; 130(7):735-747. PMID: 36870451.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    51. Daruwalla C, Hsu E, Wykoff CC, Andrieni J, Uzair S, Lee AG. INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR PHARMACEUTICAL UTILIZATION AND FINANCIAL IMPACT IN A VALUE-BASED CARE PROGRAM. Retina. 2023 03 01; 43(3):506-513. PMID: 36730588.
      Citations:    Fields:    Translation:HumansPHPublic Health
    52. Darzi AJ, Busse JW, Phillips M, Wykoff CC, Guymer RH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Interpreting results from randomized controlled trials: What measures to focus on in clinical practice. Eye (Lond). 2023 Oct; 37(15):3055-3058. PMID: 36854816; PMCID: PMC10564746.
      Citations:    Fields:    
    53. Buyse M, Wang K, Gerometta M, Baldwin ME, Price CF, Jackson TL, Slakter J, Dugel PU, Wykoff CC, Boyer DS, Opthea Study Group Investigators. A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration. Ophthalmology. 2023 06; 130(6):588-597. PMID: 36754174.
      Citations: 5     Fields:    Translation:Humans
    54. Ding L, Kang TD, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. Combining Feature Correspondence With Parametric Chamfer Alignment: Hybrid Two-Stage Registration for Ultra-Widefield Retinal Images. IEEE Trans Biomed Eng. 2023 02; 70(2):523-532. PMID: 35925847.
      Citations:    
    55. Wang R, McClard CK, Laswell S, Mahmoudzadeh R, Salabati M, Ammar M, Vannavong J, Aziz AA, Ewald A, Calvanese AV, Lehman EB, Fried S, Windham V, Strutt A, Saroj N, Khanani AM, Eichenbaum DA, Regillo C, Wykoff CC. Quantifying burden of intravitreal injections: questionnaire assessment of life impact of treatment by intravitreal injections (QUALITII). BMJ Open Ophthalmol. 2022 12; 7(1). PMID: 36794741; PMCID: PMC9764643.
      Citations:    Fields:    Translation:Humans
    56. Chaudhary V, Sarohia GS, Phillips MR, Park D, Xie J, Zeraatkar D, Fung M, Thabane L, Loewenstein A, Holz FG, Garg SJ, Kaiser PK, Bhandari M, Guymer RH, Fraser-Bell S, Sivaprasad S, Wykoff CC. Role of anti-vascular endothelial growth factor in the management of non-proliferative diabetic retinopathy without centre-involving diabetic macular oedema: a meta-analysis of trials. Eye (Lond). 2023 07; 37(10):1966-1974. PMID: 36369263; PMCID: PMC10333362.
      Citations:    Fields:    Translation:Humans
    57. Liao DS, Grossi FV, Wykoff CC, Ribeiro RM, Rosenfeld PJ, Sadda SR. Re: Minimizing risks to patients by improving presentation of clinical trial results in geographic atrophy trials (Ophthalmol Retina. 2022;6:337-338). Ophthalmol Retina. 2022 11; 6(11):1109. PMID: 36334931.
      Citations:    Fields:    Translation:Humans
    58. Wakatsuki Y, Hirabayashi K, Yu HJ, Marion KM, Corradetti G, Wykoff CC, Sadda SR. Optical Coherence Tomography Biomarkers for Conversion to Exudative Neovascular Age-related Macular Degeneration. Am J Ophthalmol. 2023 03; 247:137-144. PMID: 36228779.
      Citations: 1     Fields:    Translation:Humans
    59. Arepalli S, Wykoff CC, Abraham JR, Lunasco L, Yu H, Hu M, Srivastava SK, Reese JL, Brown D, Ehlers JP. Longitudinal analysis of aqueous humour cytokine expression and OCT-based imaging biomarkers in retinal vein occlusions treated with anti-vascular endothelial growth factor therapy in the IMAGINE study. Eye (Lond). 2023 Jun; 37(9):1928-1935. PMID: 36220884; PMCID: PMC10275974.
      Citations:    Fields:    Translation:Humans
    60. Hirabayashi K, Yu HJ, Wakatsuki Y, Marion KM, Wykoff CC, Sadda SR. OCT Risk Factors for Development of Atrophy in Eyes with Intermediate Age-Related Macular Degeneration. Ophthalmol Retina. 2023 03; 7(3):253-260. PMID: 36208726.
      Citations: 4     Fields:    Translation:Humans
    61. Fan W, Fleming A, Hemert JV, Wykoff CC, Brown DM, Robertson G, Wang K, Falavarjani KG, Sadda SR, Ip M. RETINAL VASCULAR BED AREA IN EYES WITH RETINAL VEIN OCCLUSION ON ULTRA-WIDEFIELD FLUORESCEIN ANGIOGRAPHY: WAVE Study. Retina. 2022 10 01; 42(10):1883-1888. PMID: 35976232.
      Citations:    
    62. Marcus DM, Silva PS, Liu D, Aiello LP, Antoszyk A, Elman M, Friedman S, Glassman AR, Googe JM, Jampol LM, Martin DF, Melia M, Preston CM, Wykoff CC, Sun JK, DRCR Retina Network. Association of Predominantly Peripheral Lesions on Ultra-Widefield Imaging and the Risk of Diabetic Retinopathy Worsening Over Time. JAMA Ophthalmol. 2022 10 01; 140(10):946-954. PMID: 35980608; PMCID: PMC9389433.
      Citations:    
    63. Silva PS, Marcus DM, Liu D, Aiello LP, Antoszyk A, Elman M, Friedman S, Glassman AR, Googe JM, Jampol LM, Martin DF, Melia M, Preston CM, Wykoff CC, Sun JK, DRCR Retina Network. Association of Ultra-Widefield Fluorescein Angiography-Identified Retinal Nonperfusion and the Risk of Diabetic Retinopathy Worsening Over Time. JAMA Ophthalmol. 2022 10 01; 140(10):936-945. PMID: 35980610; PMCID: PMC9389436.
      Citations:    
    64. Parvus MN, Louis AM, Trejo Corona S, Wong TP, Major JC, Patel SB, Wykoff CC. Impact of Race and Ethnicity on Presentation and Surgical Outcomes of Idiopathic Macular Holes. J Pers Med. 2022 Sep 16; 12(9). PMID: 36143303; PMCID: PMC9506218.
      Citations:    
    65. Lee IT, Corona ST, Wong TP, Flynn HW, Wykoff CC. Favorable Anti-VEGF Crunch Syndrome: Nonsurgical Relief of Vitreoretinal Traction in Eyes With Proliferative Diabetic Retinopathy and Tractional Retinal Detachment. Ophthalmic Surg Lasers Imaging Retina. 2022 08; 53(8):455-459. PMID: 35951712.
      Citations:    
    66. Do DV, Moini H, Wykoff CC. Frequency and timing of antivascular endothelial growth factor treatment for eyes with centre-involved diabetic macular oedema and good vision: Protocol V results in context. BMJ Open Ophthalmol. 2022 08; 7(1). PMID: 36161828; PMCID: PMC9345046.
      Citations: 1     Fields:    Translation:Humans
    67. Chaudhary V, Sarohia GS, Phillips MR, Zeraatkar D, Xie JS, Nanji K, Mustafa RA, Kaiser PK, Loewenstein A, Garg SJ, Bakri SJ, Holz FG, Sivaprasad S, Bhandari M, Steel DH, Wykoff CC. Role of Positioning after Full-Thickness Macular Hole Surgery: A Systematic Review and Meta-Analysis. Ophthalmol Retina. 2023 01; 7(1):33-43. PMID: 35781067.
      Citations:    Fields:    
    68. Wykoff CC, Campochiaro PA, Pieramici DJ, Khanani AM, Gune S, Maia M, Ding HT, Maass KF, K?gedal M. Pharmacokinetics of the Port Delivery System with Ranibizumab in the Ladder Phase 2 Trial for Neovascular Age-Related Macular Degeneration. Ophthalmol Ther. 2022 Oct; 11(5):1705-1717. PMID: 35759124; PMCID: PMC9437184.
      Citations:    
    69. Boone CV, Wykoff CC, Fine HF. From Bench to Bedside: Faricimab Enters the Clinic. Ophthalmic Surg Lasers Imaging Retina. 2022 Jun; 53(6):305-309. PMID: 35724370.
      Citations:    Fields:    
    70. Parpia S, Morris TP, Phillips MR, Wykoff CC, Steel DH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis. Eye (Lond). 2022 11; 36(11):2073-2074. PMID: 35585134; PMCID: PMC9581998.
      Citations:    Fields:    
    71. Nichani PAH, Dhoot AS, Popovic MM, Eshtiaghi A, Mihalache A, Sayal AP, Yu HJ, Wykoff CC, Kertes PJ, Muni RH. Scleral Buckling Alone or in Combination with Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment Repair: A Meta-Analysis of 7,212 Eyes. Ophthalmologica. 2022; 245(4):296-314. PMID: 35533652.
      Citations:    Fields:    
    72. Khanani AM, Brown DM, Jaffe GJ, Wykoff CC, Adiguzel E, Wong R, Meng X, Heier JS, MERLIN Investigators. MERLIN: Phase 3a, Multicenter, Randomized, Double-Masked Trial of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid. Ophthalmology. 2022 09; 129(9):974-985. PMID: 35537533.
      Citations:    Fields:    
    73. Khanani AM, Graff JM, Marcus DM, Wykoff CC, Jhaveri CD, Barteselli G, Malhotra VK, Menezes AR, Callaway NF. Refill-Exchange Procedure of the Port Delivery System With Ranibizumab: Overview and Clinical Trial Experience. Ophthalmic Surg Lasers Imaging Retina. 2022 05; 53(5):257-265. PMID: 35575741.
      Citations:    Fields:    Translation:Humans
    74. Sarohia GS, Nanji K, Khan M, Khalid MF, Rosenberg D, Deonarain DM, Phillips MR, Thabane L, Kaiser PK, Garg SJ, Sivaprasad S, Wykoff CC, Chaudhary V. Treat-and-extend versus alternate dosing strategies with anti-vascular endothelial growth factor agents to treat center involving diabetic macular edema: A systematic review and meta-analysis of 2,346 eyes. Surv Ophthalmol. 2022 Sep-Oct; 67(5):1346-1363. PMID: 35476929.
      Citations:    Fields:    
    75. Rosenberg D, Deonarain DM, Gould J, Sothivannan A, Phillips MR, Sarohia GS, Sivaprasad S, Wykoff CC, Cheung CMG, Sarraf D, Bakri SJ, Chaudhary V. Efficacy, safety, and treatment burden of treat-and-extend versus alternative anti-VEGF regimens for nAMD: a systematic review and meta-analysis. Eye (Lond). 2023 01; 37(1):6-16. PMID: 35396574; PMCID: PMC9829919.
      Citations:    Fields:    
    76. Sirks MJ, van Dijk EHC, Rosenberg N, Hollak CEM, Aslanis S, Cheung CMG, Chowers I, Eandi CM, Freund KB, Holz FG, Kaiser PK, Lotery AJ, Ohno-Matsui K, Querques G, Subhi Y, Tadayoni R, Wykoff CC, Zur D, Diederen RMH, Boon CJF, Schlingemann RO. Clinical impact of the worldwide shortage of verteporfin (Visudyne?) on ophthalmic care. Acta Ophthalmol. 2022 Nov; 100(7):e1522-e1532. PMID: 35388619; PMCID: PMC9790583.
      Citations: 1     Fields:    
    77. Fan W, Uji A, Wykoff CC, Brown DM, van Hemert J, Falavarjani KG, Wang K, Sadda SR, Ip M. Baseline retinal vascular bed area on ultra-wide field fluorescein angiography correlates with the anatomical outcome of diabetic macular oedema to ranibizumab therapy: two-year analysis of the DAVE Study. Eye (Lond). 2023 03; 37(4):678-683. PMID: 35332289; PMCID: PMC9998428.
      Citations:    Fields:    
    78. Wykoff CC, Nittala MG, Villanueva Boone C, Yu HJ, Fan W, Velaga SB, Ehlers JP, Ip MS, Sadda SR, RECOVERY Study Group. Final Outcomes from the Randomized RECOVERY Trial of Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2022 07; 6(7):557-566. PMID: 35257962.
      Citations:    Fields:    Translation:Humans
    79. Fan W, Nittala MG, Wykoff CC, Brown DM, Uji A, Hemert JV, Fleming A, Robertson G, Sadda SR, Ip M. NEW BIOMARKER QUANTIFYING THE EFFECT OF ANTI-VEGF THERAPY IN EYES WITH PROLIFERATIVE DIABETIC RETINOPATHY ON ULTRAWIDE FIELD FLUORESCEIN ANGIOGRAPHY: RECOVERY Study. Retina. 2022 03 01; 42(3):426-433. PMID: 34803132.
      Citations:    Fields:    Translation:Humans
    80. Dugel PU, Jhaveri CD, Chakravarthy U, Wykoff CC, Singh RP, Hamilton R, Weissgerber G, Mulyukov Z, Holz FG. EFFECT OF RETINAL THICKNESS VARIABILITY ON VISUAL OUTCOMES AND FLUID PERSISTENCE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Post Hoc Analysis of the HAWK and HARRIER Studies. Retina. 2022 03 01; 42(3):511-518. PMID: 34923515.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    81. Eshtiaghi A, Dhoot AS, Mihalache A, Popovic MM, Nichani PAH, Sayal AP, Yu HJ, Wykoff CC, Kertes PJ, Muni RH. Pars Plana Vitrectomy with and without Supplemental Scleral Buckle for the Repair of Rhegmatogenous Retinal Detachment: A Meta-analysis. Ophthalmol Retina. 2022 10; 6(10):871-885. PMID: 35227949.
      Citations: 1     Fields:    
    82. Qasim A, Devji T, Phillips MR, Wykoff CC, Kaiser PK, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Seeing the patient's perspective: a guide to patient-reported outcome measures and minimal important differences in ophthalmic research. Eye (Lond). 2022 07; 36(7):1339-1341. PMID: 35197561; PMCID: PMC9232633.
      Citations:    Fields:    Translation:Humans
    83. Phillips MR, Steel DH, Wykoff CC, Busse JW, Bannuru RR, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. A clinician's guide to network meta-analysis. Eye (Lond). 2022 08; 36(8):1523-1526. PMID: 35145277; PMCID: PMC9307840.
      Citations:    Fields:    Translation:Humans
    84. Kar SS, Abraham J, Wykoff CC, Sevgi DD, Lunasco L, Brown DM, Srivastava SK, Madabhushi A, Ehlers JP. Computational Imaging Biomarker Correlation with Intraocular Cytokine Expression in Diabetic Macular Edema: Radiomics Insights from the IMAGINE Study. Ophthalmol Sci. 2022 Jun; 2(2):100123. PMID: 36249694; PMCID: PMC9560558.
      Citations:    
    85. Bzovsky S, Phillips MR, Guymer RH, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, R.E.T.I.N.A. study group. The clinician's guide to interpreting a regression analysis. Eye (Lond). 2022 09; 36(9):1715-1717. PMID: 35102247; PMCID: PMC9391441.
      Citations:    Fields:    
    86. Wykoff CC, Abreu F, Adamis AP, Basu K, Eichenbaum DA, Haskova Z, Lin H, Loewenstein A, Mohan S, Pearce IA, Sakamoto T, Silverman D, Sun JK, Wells JA, Willis JR, YOSEMITE and RHINE Investigators, Schlottmann PG, Tadayoni R. Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials. Lancet. 2022 02 19; 399(10326):741-755. PMID: 35085503.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    87. Stenz EC, Yu HJ, Shah AR, Wong TP, Major JC, Benz MS, Wykoff CC, Patel SB. Outcomes of Eyes Undergoing Multiple Surgical Interventions after Failure of Primary Rhegmatogenous Retinal Detachment Repair. Ophthalmol Retina. 2022 05; 6(5):339-346. PMID: 35074559.
      Citations:    Fields:    Translation:Humans
    88. Wykoff CC, Yu HJ, Avery RL, Ehlers JP, Sadda SR, Tadayoni R. Retinal non-perfusion in diabetic retinopathy. Eye (Lond). 2022 02; 36(2):249-256. PMID: 35017700; PMCID: PMC8807828.
      Citations:    Fields:    Translation:Humans
    89. Khanani AM, Zarbin MA, Barakat MR, Albini TA, Kaiser PK, B G, Agashivala N, Yu JS, Wykoff CC, MacCumber MW. Safety Outcomes of Brolucizumab in Neovascular Age-Related Macular Degeneration: Results From the IRIS Registry and Komodo Healthcare Map. JAMA Ophthalmol. 2022 Jan 01; 140(1):20-28. PMID: 34817566; PMCID: PMC8613703.
      Citations: 3     Fields:    Translation:Humans
    90. Eter N, Singh RP, Abreu F, Asik K, Basu K, Baumal C, Chang A, Csaky KG, Haskova Z, Lin H, Ruiz CQ, Ruamviboonsuk P, Silverman D, Wykoff CC, Willis JR. YOSEMITE and RHINE: Phase 3 Randomized Clinical Trials of Faricimab for Diabetic Macular Edema: Study Design and Rationale. Ophthalmol Sci. 2022 Mar; 2(1):100111. PMID: 36246184; PMCID: PMC9559760.
      Citations: 6     
    91. Singh RP, Jhaveri C, Wykoff CC, Gale RP, Staurenghi G, Iida T, Koh A, B G, Gedif K, Singer M. Efficacy Outcomes of Brolucizumab Versus Aflibercept in Neovascular Age-Related Macular Degeneration Patients with Early Residual Fluid. Ophthalmol Retina. 2022 05; 6(5):377-386. PMID: 34968756.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    92. Chao DL, Rinella NT, Khanani AM, Wykoff CC, Kim GH. Cooling Anesthesia for Intravitreal Injection: Results of the Prospective Open-Label, Dose-Ranging COOL-1 Trial. Clin Ophthalmol. 2021; 15:4659-4666. PMID: 34916777; PMCID: PMC8670887.
      Citations:    Translation:CTClinical Trials
    93. Dhoot AS, Popovic MM, Nichani PAH, Eshtiaghi A, Mihalache A, Sayal AP, Yu H, Wykoff CC, Kertes PJ, Muni RH. Pars plana vitrectomy versus scleral buckle: A comprehensive meta-analysis of 15,947 eyes. Surv Ophthalmol. 2022 Jul-Aug; 67(4):932-949. PMID: 34896191.
      Citations: 2     Fields:    Translation:Humans
    94. Nanji K, Sarohia GS, Kennedy K, Ceyhan T, McKechnie T, Phillips M, Devji T, Thabane L, Kaiser P, Sarraf D, Garg SJ, Sivaprasad S, Wykoff CC, Bakri SJ, Sheidow T, Bhandari M, Chaudhary V. The 12- and 24-Month Effects of Intravitreal Ranibizumab, Aflibercept, and Bevacizumab on Intraocular Pressure: A Network Meta-Analysis. Ophthalmology. 2022 05; 129(5):498-508. PMID: 34871637.
      Citations:    Fields:    Translation:Humans
    95. Yu JS, Sagkriotis A, B G, Agashivala N, MacCumber MW, Burugapalli B, Bi X, Wykoff CC. Antivascular endothelial growth factor agents for wet age-related macular degeneration: an IRIS registry analysis. Can J Ophthalmol. 2023 06; 58(3):252-261. PMID: 34863677.
      Citations:    Fields:    
    96. Nanji K, Khan M, Khalid MF, Xie JS, Sarohia GS, Phillips M, Thabane L, Garg SJ, Kaiser P, Sivaprasad S, Wykoff CC, Chaudhary V. Treat-and-extend regimens of anti-vascular endothelial growth factor therapy for retinal vein occlusions: a systematic review and meta-analysis. Acta Ophthalmol. 2022 Sep; 100(6):e1199-e1208. PMID: 34845830.
      Citations:    Fields:    
    97. Phillips MR, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. The clinician's guide to p values, confidence intervals, and magnitude of effects. Eye (Lond). 2022 02; 36(2):341-342. PMID: 34837035; PMCID: PMC8807597.
      Citations:    Fields:    Translation:Humans
    98. Rosenberg DM, Ghayur HS, Deonarain DM, Sarohia GS, Phillips MR, Garg S, Bakri SJ, Wykoff CC, Chaudhary V. Supplemental Scleral Buckle for the Management of Rhegmatogenous Retinal Detachment by Pars Plana Vitrectomy: A Meta-Analysis of Randomized Controlled Trials. Ophthalmologica. 2022; 245(2):101-110. PMID: 34731858.
      Citations:    Fields:    Translation:Humans
    99. Babiuch AS, Wykoff CC, Yordi S, Yu H, Srivastava SK, Hu M, Le TK, Lunasco L, Reese J, Nittala MG, Sadda SR, Ehlers JP. The 2-Year Leakage Index and Quantitative Microaneurysm Results of the RECOVERY Study: Quantitative Ultra-Widefield Findings in Proliferative Diabetic Retinopathy Treated with Intravitreal Aflibercept. J Pers Med. 2021 Nov 01; 11(11). PMID: 34834478; PMCID: PMC8619795.
      Citations: 1     
    100. Jhaveri C, Wykoff CC, Khanani AM, Eandi CM, Chang A, B G, Gedif KA, Singer M. Early Residual Fluid-Free Status and Long-Term BCVA Outcomes: A Treatment Agnostic, Post Hoc Analysis of Pooled HAWK and HARRIER Data. Am J Ophthalmol. 2022 04; 236:12-19. PMID: 34695400.
      Citations:    Fields:    Translation:Humans
    101. Ding L, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. Weakly-Supervised Vessel Detection in Ultra-Widefield Fundus Photography via Iterative Multi-Modal Registration and Learning. IEEE Trans Med Imaging. 2021 10; 40(10):2748-2758. PMID: 32991281; PMCID: PMC8513803.
      Citations: 6     Fields:    Translation:Humans
    102. Fang M, Chanwimol K, Maram J, Datoo O'Keefe GA, Wykoff CC, Sarraf D, Brown A, Lampen SIR, Zhou B, Rusakevich AM, Sadda S. Morphological characteristics of eyes with neovascular age-related macular degeneration and good long-term visual outcomes after anti-VEGF therapy. Br J Ophthalmol. 2023 03; 107(3):399-405. PMID: 34561217.
      Citations:    Fields:    
    103. Wykoff CC, Hershberger V, Eichenbaum D, Henry E, Younis HS, Chandra P, Yuan N, Solloway M, DePaoli A. Inhibition of Complement Factor 3 in Geographic Atrophy with NGM621: Phase 1 Dose-Escalation Study Results. Am J Ophthalmol. 2022 03; 235:131-142. PMID: 34509438.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    104. Yu HJ, Ehlers JP, Sevgi DD, O'Connell M, Reese JL, Srivastava SK, Wykoff CC. Real-Time Diabetic Retinopathy Severity Score Level versus Ultra-Widefield Leakage Index-Guided Management of Diabetic Retinopathy: Two-Year Outcomes from the Randomized PRIME Trial. J Pers Med. 2021 Sep 04; 11(9). PMID: 34575662; PMCID: PMC8465170.
      Citations: 1     
    105. Heier JS, Singh RP, Wykoff CC, Csaky KG, Lai TYY, Loewenstein A, Schlottmann PG, Paris LP, Westenskow PD, Quezada-Ruiz C. Reply. Retina. 2021 09 01; 41(9):e56-e58. PMID: 34432748.
      Citations:    Fields:    
    106. Brown DM, Wykoff CC, Boyer D, Heier JS, Clark WL, Emanuelli A, Higgins PM, Singer M, Weinreich DM, Yancopoulos GD, Berliner AJ, Chu K, Reed K, Cheng Y, Vitti R. Evaluation of Intravitreal Aflibercept for the Treatment of Severe Nonproliferative Diabetic Retinopathy: Results From the PANORAMA Randomized Clinical Trial. JAMA Ophthalmol. 2021 Sep 01; 139(9):946-955. PMID: 34351414; PMCID: PMC8343518.
      Citations: 7     Fields:    Translation:Humans
    107. Sevgi DD, Srivastava SK, Wykoff C, Scott AW, Hach J, O'Connell M, Whitney J, Vasanji A, Reese JL, Ehlers JP. Deep learning-enabled ultra-widefield retinal vessel segmentation with an automated quality-optimized angiographic phase selection tool. Eye (Lond). 2022 09; 36(9):1783-1788. PMID: 34373610; PMCID: PMC9391395.
      Citations:    Fields:    
    108. Kaiser PK, Wykoff CC, Singh RP, Khanani AM, Do DV, Patel H, Patel N. RETINAL FLUID AND THICKNESS AS MEASURES OF DISEASE ACTIVITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Retina. 2021 Aug 01; 41(8):1579-1586. PMID: 33949342; PMCID: PMC8297539.
      Citations: 3     Fields:    Translation:Humans
    109. Jain N, Liao A, Garg SJ, Patel SN, Wykoff CC, Yu HJ, London NJS, Khurana RN, Zacks DN, Macula Society Pentosan Polysulfate Maculopathy Study Group. Expanded Clinical Spectrum of Pentosan Polysulfate Maculopathy: A Macula Society Collaborative Study. Ophthalmol Retina. 2022 03; 6(3):219-227. PMID: 34298229.
      Citations: 1     Fields:    Translation:Humans
    110. Abraham JR, Wykoff CC, Arepalli S, Lunasco L, Yu HJ, Martin A, Mugnaini C, Hu M, Reese J, Srivastava SK, Brown DM, Ehlers JP. Exploring the angiographic-biologic phenotype in the IMAGINE study: quantitative UWFA and cytokine expression. Br J Ophthalmol. 2022 10; 106(10):1444-1449. PMID: 34099465; PMCID: PMC8761372.
      Citations: 2     Fields:    
    111. Yu JS, Carlton R, Agashivala N, Hassan T, Wykoff CC. Brolucizumab vs aflibercept and ranibizumab for neovascular age-related macular degeneration: a cost-effectiveness analysis. J Manag Care Spec Pharm. 2021 Jun; 27(6):743-752. PMID: 34057392; PMCID: PMC10390922.
      Citations: 3     Fields:    Translation:Humans
    112. Heier JS, Brown DM, Shah SP, Saroj N, Dang S, Waheed NK, Wykoff CC, Prenner JL, Boyer DS. Intravitreal Aflibercept Injection vs Sham as Prophylaxis Against Conversion to Exudative Age-Related Macular Degeneration in High-risk Eyes: A Randomized Clinical Trial. JAMA Ophthalmol. 2021 May 01; 139(5):542-547. PMID: 33734306; PMCID: PMC7974836.
      Citations: 1     Fields:    Translation:Humans
    113. Yu HJ, Wykoff CC. Investigational Agents in Development for the Treatment of Geographic Atrophy Secondary to Age-Related Macular Degeneration. BioDrugs. 2021 May; 35(3):303-323. PMID: 33893984.
      Citations: 1     Fields:    Translation:Humans
    114. McClard CK, Wang R, Windham V, Munoz J, Gomez S, Fried S, Saroj N, Regillo C, Wykoff CC, Strutt AM. Questionnaire to Assess Life Impact of Treatment by Intravitreal Injections (QUALITII): Development of a patient-reported measure to assess treatment burden of repeat intravitreal injections. BMJ Open Ophthalmol. 2021; 6(1):e000669. PMID: 33912685; PMCID: PMC8031709.
      Citations: 3     
    115. Fan W, Uji A, Nittala M, Wykoff CC, Brown D, Fleming A, Robertson G, van Hemert J, Sadda S, Ip MS. Retinal vascular bed area on ultra-wide field fluorescein angiography indicates the severity of diabetic retinopathy. Br J Ophthalmol. 2022 08; 106(8):1126-1131. PMID: 33827861.
      Citations: 3     Fields:    Translation:Humans
    116. Breazzano MP, Nair AA, Arevalo JF, Barakat MR, Berrocal AM, Chang JS, Chen A, Eliott D, Garg SJ, Ghadiali Q, Gong D, Grewal DS, Handa JT, Henderson M, Leiderman YI, Leng T, Mannina A, Mendel TA, Mustafi D, de Koo LCO, Patel SN, Patel TP, Prenner J, Richards P, Singh RP, Wykoff CC, Yannuzzi NA, Yu H, Modi YS, Chang S. Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic. JAMA Ophthalmol. 2021 04 01; 139(4):456-463. PMID: 33662093; PMCID: PMC7934075.
      Citations: 13     Fields:    Translation:HumansCells
    117. Wykoff CC, Rosenfeld PJ, Waheed NK, Singh RP, Ronca N, Slakter JS, Staurenghi G, Baumal CR, Saroj N, Metlapally R, Ribeiro R, Mon?s J. Characterizing New-Onset Exudation in the Randomized Phase 2 FILLY Trial of Complement Inhibitor Pegcetacoplan for Geographic Atrophy. Ophthalmology. 2021 09; 128(9):1325-1336. PMID: 33711380.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    118. Yu HJ, Ehlers JP, Sevgi DD, Hach J, O'Connell M, Reese JL, Srivastava SK, Wykoff CC. Real-Time Photographic- and Fluorescein Angiographic-Guided Management of Diabetic Retinopathy: Randomized PRIME Trial Outcomes. Am J Ophthalmol. 2021 06; 226:126-136. PMID: 33529593.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    119. Wykoff CC, Khurana RN, Nguyen QD, Kelly SP, Lum F, Hall R, Abbass IM, Abolian AM, Stoilov I, To TM, Garmo V. Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy. Diabetes Care. 2021 03; 44(3):748-756. PMID: 33472864; PMCID: PMC7896265.
      Citations: 7     Fields:    Translation:Humans
    120. Heier JS, Singh RP, Wykoff CC, Csaky KG, Lai TYY, Loewenstein A, Schlottmann PG, Paris LP, Westenskow PD, Quezada-Ruiz C. THE ANGIOPOIETIN/TIE PATHWAY IN RETINAL VASCULAR DISEASES: A Review. Retina. 2021 01 01; 41(1):1-19. PMID: 33136975.
      Citations: 4     Fields:    Translation:HumansCells
    121. Yu HJ, Kiernan DF, Eichenbaum D, Sheth VS, Wykoff CC. Reply. Ophthalmol Retina. 2021 01; 5(1):e1-e2. PMID: 33413801.
      Citations:    Fields:    Translation:Humans
    122. Khurana RN, Kunimoto D, Yoon YH, Wykoff CC, Chang A, Maturi RK, Souied E, Chow DR, Lotery AJ, Ohji M, Bandello F, Li XY, Jiao J, Le G, Kim K, Schmidt W, Hashad Y, CEDAR and SEQUOIA Study Groups, Agostini H, Belfort R. Two-Year Results of the Phase 3 Randomized Controlled Study of Abicipar in Neovascular Age-Related Macular Degeneration. Ophthalmology. 2021 07; 128(7):1027-1038. PMID: 33221326.
      Citations: 7     Fields:    Translation:Humans
    123. Singer MA, Wykoff CC, Grewal DS. Effects of Long-Term DME Control With 0.2 ?g/Day Fluocinolone Acetonide Implant on Quality of Life: An Exploratory Analysis From the FAME Trial. Ophthalmic Surg Lasers Imaging Retina. 2020 11 01; 51(11):658-667. PMID: 33231701.
      Citations:    Fields:    Translation:Humans
    124. Babiuch AS, Wykoff CC, Srivastava SK, Talcott K, Zhou B, Hach J, Hu M, Reese JL, Ehlers JP. RETINAL LEAKAGE INDEX DYNAMICS ON ULTRA-WIDEFIELD FLUORESCEIN ANGIOGRAPHY IN EYES TREATED WITH INTRAVITREAL AFLIBERCEPT FOR PROLIFERATIVE DIABETIC RETINOPATHY IN THE RECOVERY STUDY. Retina. 2020 Nov; 40(11):2175-2183. PMID: 31917731.
      Citations: 3     Fields:    Translation:Humans
    125. Wan CR, Kapik B, Wykoff CC, Henry CR, Barakat MR, Shah M, Andino RV, Ciulla TA. Clinical Characterization of Suprachoroidal Injection Procedure Utilizing a Microinjector across Three Retinal Disorders. Transl Vis Sci Technol. 2020 10; 9(11):27. PMID: 33150052; PMCID: PMC7585395.
      Citations: 1     Fields:    Translation:Humans
    126. Bawany MH, Ding L, Ramchandran RS, Sharma G, Wykoff CC, Kuriyan AE. Automated vessel density detection in fluorescein angiography images correlates with vision in proliferative diabetic retinopathy. PLoS One. 2020; 15(9):e0238958. PMID: 32915904; PMCID: PMC7485882.
      Citations: 3     Fields:    Translation:Humans
    127. Abraham JR, Wykoff CC, Arepalli S, Lunasco L, Yu HJ, Hu M, Reese J, Srivastava SK, Brown DM, Ehlers JP. Aqueous Cytokine Expression and Higher Order OCT Biomarkers: Assessment of the Anatomic-Biologic Bridge in the IMAGINE DME Study. Am J Ophthalmol. 2021 02; 222:328-339. PMID: 32896498; PMCID: PMC9719825.
      Citations: 6     Fields:    Translation:Humans
    128. Alagorie AR, Velaga S, Nittala MG, Yu HJ, Wykoff CC, Sadda SR. Effect of Aflibercept on Diabetic Retinopathy Severity and Visual Function in the RECOVERY Study for Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2021 05; 5(5):409-419. PMID: 32882447.
      Citations: 1     Fields:    Translation:Humans
    129. Gupta MP, Sridhar J, Wykoff CC, Yonekawa Y. Ophthalmology conferences in the coronavirus disease 2019 era. Curr Opin Ophthalmol. 2020 Sep; 31(5):396-402. PMID: 32740066.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    130. Chen A, Dang S, Chung MM, Ramchandran RS, Bessette AP, DiLoreto DA, Kleinman DM, Sridhar J, Wykoff CC, Kuriyan AE. Quantitative Comparison of Fundus Images by 2 Ultra-Widefield Fundus Cameras. Ophthalmol Retina. 2021 05; 5(5):450-457. PMID: 32866664; PMCID: PMC8501635.
      Citations: 3     Fields:    Translation:Humans
    131. Babiuch A, Wykoff CC, Hach J, Srivastava S, Talcott KE, Yu HJ, Nittala M, Sadda S, Ip MS, Le T, Hu M, Reese J, Ehlers JP. Longitudinal panretinal microaneurysm dynamics on ultra-widefield fluorescein angiography in eyes treated with intravitreal aflibercept for proliferative diabetic retinopathy in the recovery study. Br J Ophthalmol. 2021 08; 105(8):1111-1115. PMID: 32829304.
      Citations: 5     Fields:    Translation:Humans
    132. Barakat MR, Wykoff CC, Gonzalez V, Hu A, Marcus D, Zavaleta E, Ciulla TA. Suprachoroidal CLS-TA plus Intravitreal Aflibercept for Diabetic Macular Edema: A Randomized, Double-Masked, Parallel-Design, Controlled Study. Ophthalmol Retina. 2021 01; 5(1):60-70. PMID: 32829027.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    133. Yu HJ, Kiernan DF, Eichenbaum D, Sheth VS, Wykoff CC. Home Monitoring of Age-Related Macular Degeneration: Utility of the ForeseeHome Device for Detection of Neovascularization. Ophthalmol Retina. 2021 04; 5(4):348-356. PMID: 32810682; PMCID: PMC7428765.
      Citations: 3     Fields:    Translation:Humans
    134. Alagorie AR, Nittala MG, Velaga S, Zhou B, Rusakevich AM, Wykoff CC, Sadda SR. Association of Intravitreal Aflibercept With Optical Coherence Tomography Angiography Vessel Density in Patients With Proliferative Diabetic Retinopathy: A Secondary Analysis of a Randomized Clinical Trial. JAMA Ophthalmol. 2020 08 01; 138(8):851-857. PMID: 32584384; PMCID: PMC7317653.
      Citations: 9     Fields:    Translation:Humans
    135. Chao DL, Sridhar J, Kuriyan AE, Leng T, Barnett BP, Carlin AF, Wykoff CC, Gayer S, Mruthyunjaya P, Yonekawa Y, Fawzi AA, Berrocal AM, Yeh S, Ting D, Modi Y, Zacks DN, Yannuzzi N, Afshari NA, Murray T. Rationale for American Society of Retina Specialists Best Practice Recommendations for Conducting Vitreoretinal Surgery during the COVID-19 Era. J Vitreoretin Dis. 2020 Oct 01; 4(5):420-429. PMID: 34222758; PMCID: PMC8247449.
      Citations:    
    136. Hussain RM, Weng CY, Wykoff CC, Gandhi RA, Hariprasad SM. Abicipar pegol for neovascular age-related macular degeneration. Expert Opin Biol Ther. 2020 09; 20(9):999-1008. PMID: 32552072.
      Citations: 4     Fields:    Translation:HumansCells
    137. Fan W, Uji A, Wang K, Falavarjani KG, Wykoff CC, Brown DM, Van Hemert J, Sagong M, Sadda SR, Ip M. SEVERITY OF DIABETIC MACULAR EDEMA CORRELATES WITH RETINAL VASCULAR BED AREA ON ULTRA-WIDE FIELD FLUORESCEIN ANGIOGRAPHY: DAVE Study. Retina. 2020 Jun; 40(6):1029-1037. PMID: 31356494.
      Citations: 8     Fields:    Translation:Humans
    138. Puliafito CA, Wykoff CC. New Frontiers in Retina: highlights of the 2020 angiogenesis, exudation and degeneration symposium. Int J Retina Vitreous. 2020; 6:18. PMID: 32477592; PMCID: PMC7243329.
      Citations: 6     
    139. Ding L, Bawany MH, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. A Novel Deep Learning Pipeline for Retinal Vessel Detection In Fluorescein Angiography. IEEE Trans Image Process. 2020 May 08. PMID: 32396087; PMCID: PMC7648732.
      Citations: 4     Fields:    
    140. Yu HJ, Kaiser PK, Zamora D, Bocanegra M, Cone C, Brown DM, Sadda SR, Wykoff CC. Visual Acuity Variability: Comparing Discrepancies between Snellen and ETDRS Measurements among Subjects Entering Prospective Trials. Ophthalmol Retina. 2021 03; 5(3):224-233. PMID: 32595096.
      Citations: 2     Fields:    Translation:Humans
    141. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Long-term outcomes of treat-and-extend ranibizumab with and without navigated laser for diabetic macular oedema: TREX-DME 3-year results. Br J Ophthalmol. 2021 02; 105(2):253-257. PMID: 32303499.
      Citations:    Fields:    Translation:Humans
    142. Kunimoto D, Yoon YH, Wykoff CC, Chang A, Khurana RN, Maturi RK, Souied E, Chow DR, Lotery AJ, Ohji M, Bandello F, Li XY, Jiao J, Le G, Schmidt W, Hashad Y, CEDAR and SEQUOIA Study Groups, Agostini H, Belfort R. Efficacy and Safety of Abicipar in Neovascular Age-Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study. Ophthalmology. 2020 10; 127(10):1331-1344. PMID: 32471729.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    143. Glassman AR, Baker CW, Beaulieu WT, Bressler NM, Punjabi OS, Stockdale CR, Wykoff CC, Jampol LM, Sun JK, DRCR Retina Network. Assessment of the DRCR Retina Network Approach to Management With Initial Observation for Eyes With Center-Involved Diabetic Macular Edema and Good Visual Acuity: A Secondary Analysis of a Randomized Clinical Trial. JAMA Ophthalmol. 2020 04 01; 138(4):341-349. PMID: 32077907; PMCID: PMC7042938.
      Citations: 11     Fields:    Translation:Humans
    144. Suresh R, Yu HJ, Thoveson A, Swisher J, Apolinario M, Zhou B, Shah AR, Fish RH, Wykoff CC. Loss to Follow-Up Among Patients With Proliferative Diabetic Retinopathy in Clinical Practice. Am J Ophthalmol. 2020 07; 215:66-71. PMID: 32209344.
      Citations: 2     Fields:    Translation:Humans
    145. Major JC, Lampen SIR, Wykoff CC, Ou WC, Brown DM, Wong TP, Shah AR. THE TEXAS TACO TECHNIQUE FOR INTERNAL LIMITING MEMBRANE FLAP IN LARGE FULL-THICKNESS MACULAR HOLES: A Short-Term Pilot Study. Retina. 2020 Mar; 40(3):552-556. PMID: 30608347.
      Citations: 1     Fields:    Translation:Humans
    146. Campbell J, Almony A, Shih V, Serbin M, LaPrise A, Wykoff CC, Kiss S. Management and Outcomes for Neovascular Age-Related Macular Degeneration: Analysis of United States Electronic Health Records. Ophthalmology. 2020 09; 127(9):1179-1188. PMID: 32345477.
      Citations: 4     Fields:    Translation:Humans
    147. Yonekawa Y, Modi YS, Kim LA, Skondra D, Kim JE, Wykoff CC. American Society of Retina Specialists Clinical Practice Guidelines on the Management of Nonproliferative and Proliferative Diabetic Retinopathy without Diabetic Macular Edema. J Vitreoretin Dis. 2020 Mar 01; 4(2):125-135. PMID: 34308094; PMCID: PMC8297841.
      Citations:    
    148. Holekamp N, Wykoff CC, Schmitz-Valckenberg S, Lin H, Rabena MD, Cantrell RA, Henry EC, Tang F, Swaminathan B, Martin J, Ferrara D, Staurenghi G, Mon?s J, Souied EH. Natural History of Geographic Atrophy Secondary to Age-Related Macular Degeneration: Results from the Prospective Proxima A and B Clinical Trials. Ophthalmology. 2020 06; 127(6):769-783. PMID: 32081489.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    149. Zhou B, Mitchell TC, Rusakevich AM, Brown DM, Wykoff CC. Noncompliance in Prospective Retina Clinical Trials: Analysis of Factors Predicting Loss to Follow-up. Am J Ophthalmol. 2020 02; 210:86-96. PMID: 31647931.
      Citations: 3     Fields:    Translation:Humans
    150. Hinkle JW, Wykoff CC, Lim JI, Hahn P, Kim SJ, Tabandeh H, Flynn HW. "Iodine Allergy" and the Use of Povidone Iodine for Endophthalmitis Prophylaxis. J Vitreoretin Dis. 2020 Jan-Feb; 4(1):65-68. PMID: 37009565; PMCID: PMC9976080.
      Citations:    
    151. Singh RP, Hsueh J, Han MM, Kuriyan AE, Conti FF, Steinle N, Weng CY, Wong RW, Martinez JA, Wykoff CC. Protecting Vision in Patients With Diabetes With Ultra-Widefield Imaging: A Review of Current Literature. Ophthalmic Surg Lasers Imaging Retina. 2019 10 01; 50(10):639-648. PMID: 31671197.
      Citations: 1     Fields:    Translation:Humans
    152. Heier JS, Wykoff CC, Waheed NK, Kitchens JW, Patel SS, Vitti R, Perlee L, Chu KW, Leal S, Asmus F, Son V, Schmelter T, Brown DM. Intravitreal Combined Aflibercept?+ Anti-Platelet-Derived Growth Factor Receptor ? for Neovascular Age-Related Macular Degeneration: Results of the Phase 2 CAPELLA Trial. Ophthalmology. 2020 02; 127(2):211-220. PMID: 31791663.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    153. Rusakevich AM, Zhou B, Wong TP, Wykoff CC. Quarterly Anti-Vascular Endothelial Growth Factor Dosing for Neovascular Age-Related Macular Degeneration: Real-World Clinical Outcomes. Ophthalmic Surg Lasers Imaging Retina. 2019 09 01; 50(9):e250-e256. PMID: 31589766.
      Citations: 1     Fields:    Translation:Humans
    154. Fan W, Nittala MG, Fleming A, Robertson G, Uji A, Wykoff CC, Brown DM, van Hemert J, Ip M, Wang K, Falavarjani KG, Singer M, Sagong M, Sadda SR. Relationship Between Retinal Fractal Dimension and Nonperfusion in Diabetic Retinopathy on Ultrawide-Field Fluorescein Angiography. Am J Ophthalmol. 2020 01; 209:99-106. PMID: 31472160.
      Citations: 9     Fields:    Translation:Humans
    155. Wykoff CC, Nittala MG, Zhou B, Fan W, Velaga SB, Lampen SIR, Rusakevich AM, Ehlers JP, Babiuch A, Brown DM, Ip MS, Sadda SR, Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy Study Group. Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy: Outcomes from the Randomized RECOVERY Trial. Ophthalmol Retina. 2019 12; 3(12):1076-1086. PMID: 31542339.
      Citations: 17     Fields:    Translation:Humans
    156. Wykoff CC. Thresholds for Initiating Treatment of Eyes with Diabetic Macular Edema and Good Vision: Consideration of DRCR.Net Protocol V Results. Ophthalmol Retina. 2019 11; 3(11):917-919. PMID: 31699307.
      Citations: 2     Fields:    Translation:Humans
    157. Sadda SR, Campbell J, Dugel PU, Holekamp NM, Loewenstein A, Augustin AJ, Shih V, Xu X, Wykoff CC, Whitcup SM, Kiss S. Relationship between duration and extent of oedema and visual acuity outcome with ranibizumab in diabetic macular oedema: A post hoc analysis of Protocol I data. Eye (Lond). 2020 03; 34(3):480-490. PMID: 31320738; PMCID: PMC7042302.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    158. Liao DS, Grossi FV, El Mehdi D, Gerber MR, Brown DM, Heier JS, Wykoff CC, Singerman LJ, Abraham P, Grassmann F, Nuernberg P, Weber BHF, Deschatelets P, Kim RY, Chung CY, Ribeiro RM, Hamdani M, Rosenfeld PJ, Boyer DS, Slakter JS, Francois CG. Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial. Ophthalmology. 2020 02; 127(2):186-195. PMID: 31474439.
      Citations: 59     Fields:    Translation:HumansCTClinical Trials
    159. Apolinario MA, Lampen SIR, Wong TP, Henry CR, Wykoff CC. Office-based intravitreal injection of expansile gas for management of macular hole in previously vitrectomized eyes. Am J Ophthalmol Case Rep. 2019 Sep; 15:100492. PMID: 31334383; PMCID: PMC6614528.
      Citations:    
    160. Puliafito CA, Wykoff CC. Looking ahead in retinal disease management: highlights of the 2019 angiogenesis, exudation and degeneration symposium. Int J Retina Vitreous. 2019; 5:22. PMID: 31161069; PMCID: PMC6542006.
      Citations: 3     
    161. Fan W, Nittala MG, Velaga SB, Hirano T, Wykoff CC, Ip M, Lampen SIR, van Hemert J, Fleming A, Verhoek M, Sadda SR. Distribution of Nonperfusion and Neovascularization on Ultrawide-Field Fluorescein Angiography in Proliferative Diabetic Retinopathy (RECOVERY Study): Report 1. Am J Ophthalmol. 2019 10; 206:154-160. PMID: 31078541.
      Citations: 14     Fields:    Translation:Humans
    162. Lynch SK, Lee K, Chen Z, Folk JC, Schmidt-Erfurth U, Gerendas BS, Wahle A, Wykoff CC, Abr?moff MD. Intravitreal Fluocinolone Acetonide May Decelerate Diabetic Retinal Neurodegeneration. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):2134-2139. PMID: 31100106; PMCID: PMC6528841.
      Citations: 6     Fields:    Translation:Humans
    163. Fang M, Fan W, Shi Y, Ip MS, Wykoff CC, Wang K, Falavarjani KG, Brown DM, van Hemert J, Sadda SR. Classification of Regions of Nonperfusion on Ultra-widefield Fluorescein Angiography in Patients with Diabetic Macular Edema. Am J Ophthalmol. 2019 10; 206:74-81. PMID: 30959003.
      Citations: 11     Fields:    Translation:Humans
    164. Chaturvedi R, Wannamaker KW, Riviere PJ, Khanani AM, Wykoff CC, Chao DL. Real-World Trends in Intravitreal Injection Practices among American Retina Specialists. Ophthalmol Retina. 2019 08; 3(8):656-662. PMID: 31133544; PMCID: PMC6684447.
      Citations: 5     Fields:    Translation:Humans
    165. Wykoff CC, Shah C, Dhoot D, Coleman HR, Thompson D, Du W, Baker K, Vitti R, Berliner AJ, Metzig C, Saroj N. Longitudinal Retinal Perfusion Status in Eyes with Diabetic Macular Edema Receiving Intravitreal Aflibercept or Laser in VISTA?Study. Ophthalmology. 2019 08; 126(8):1171-1180. PMID: 30946887.
      Citations: 16     Fields:    Translation:Humans
    166. Sahni J, Patel SS, Dugel PU, Khanani AM, Jhaveri CD, Wykoff CC, Hershberger VS, Pauly-Evers M, Sadikhov S, Szczesny P, Schwab D, Nogoceke E, Osborne A, Weikert R, Fauser S. Simultaneous Inhibition of Angiopoietin-2 and Vascular Endothelial Growth Factor-A with Faricimab in Diabetic Macular Edema: BOULEVARD Phase 2 Randomized Trial. Ophthalmology. 2019 08; 126(8):1155-1170. PMID: 30905643.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    167. Wykoff CC, Rusakevich AM, Moshfeghi DM. Re: Adrean et?al.: Consistent long-term therapy of neovascular age-related macular degeneration managed by 50 or more anti-VEGF injections using a treat-extend-stop protocol (Ophthalmology. 2018;125:1047-1053). Ophthalmology. 2019 03; 126(3):e18-e19. PMID: 30803522.
      Citations:    Fields:    Translation:Humans
    168. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Randomized Trial of Treat and Extend Ranibizumab With and Without Navigated Laser Versus Monthly Dosing for Diabetic Macular Edema: TREX-DME 2-Year Outcomes. Am J Ophthalmol. 2019 06; 202:91-99. PMID: 30771333.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    169. Habot-Wilner Z, Noronha G, Wykoff CC. Suprachoroidally injected pharmacological agents for the treatment of chorio-retinal diseases: a targeted approach. Acta Ophthalmol. 2019 Aug; 97(5):460-472. PMID: 30702218.
      Citations: 15     Fields:    Translation:Humans
    170. Lee IT, Lampen SIR, Wong TP, Major JC, Wykoff CC. Fovea-sparing rhegmatogenous retinal detachments: impact of clinical factors including time to surgery on visual and anatomic outcomes. Graefes Arch Clin Exp Ophthalmol. 2019 May; 257(5):883-889. PMID: 30635720.
      Citations: 5     Fields:    Translation:Humans
    171. Aiello LP, Odia I, Glassman AR, Melia M, Jampol LM, Bressler NM, Kiss S, Silva PS, Wykoff CC, Sun JK, Diabetic Retinopathy Clinical Research Network. Comparison of Early Treatment Diabetic Retinopathy Study Standard 7-Field Imaging With Ultrawide-Field Imaging for Determining Severity of Diabetic Retinopathy. JAMA Ophthalmol. 2019 01 01; 137(1):65-73. PMID: 30347105; PMCID: PMC6439787.
      Citations: 29     Fields:    Translation:Humans
    172. Wykoff CC, Hariprasad SM, Zhou B. Innovation in Neovascular Age-Related Macular Degeneration: Consideration of Brolucizumab, Abicipar, and the Port Delivery System. Ophthalmic Surg Lasers Imaging Retina. 2018 12 01; 49(12):913-917. PMID: 30566697.
      Citations: 1     Fields:    Translation:Humans
    173. Lampen SIR, Khurana RN, Noronha G, Brown DM, Wykoff CC. Suprachoroidal Space Alterations Following Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients With Diabetic Macular Edema. Ophthalmic Surg Lasers Imaging Retina. 2018 09 01; 49(9):692-697. PMID: 30222804.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    174. Wykoff CC, Eichenbaum DA, Roth DB, Hill L, Fung AE, Haskova Z. Ranibizumab Induces Regression of Diabetic Retinopathy in Most Patients at High Risk of Progression to Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2018 10; 2(10):997-1009. PMID: 31047503.
      Citations: 20     Fields:    
    175. Amram AL, Mandviwala MM, Ou WC, Wykoff CC, Shah AR. Predictors of Visual Acuity Outcomes Following Vitrectomy for Idiopathic Macular Hole. Ophthalmic Surg Lasers Imaging Retina. 2018 08 01; 49(8):566-570. PMID: 30114300.
      Citations: 2     Fields:    Translation:Humans
    176. Wang K, Ghasemi Falavarjani K, Nittala MG, Sagong M, Wykoff CC, van Hemert J, Ip M, Sadda SR. Ultra-Wide-Field Fluorescein Angiography-Guided Normalization of Ischemic Index Calculation in Eyes With Retinal Vein Occlusion. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3278-3285. PMID: 29971447.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    177. Eichenbaum DA, Buznego C, Weng CY, Dhoot DS, Wykoff CC, Sheth VS. When and How to Incorporate Steroids for Persistent Diabetic Macular Edema: A Discussion of Real-World Treatment Optimization Strategies. Ophthalmic Surg Lasers Imaging Retina. 2018 07 01; 49(7):S5-S15. PMID: 30021031.
      Citations: 4     Fields:    Translation:Humans
    178. Abdelfattah NS, Hariri AH, Al-Sheikh M, Pitetta S, Ebraheem A, Wykoff CC, Sadda SR, TREX-AMD Study Group. Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial. Am J Ophthalmol. 2018 08; 192:84-90. PMID: 29763612.
      Citations: 2     Fields:    Translation:Humans
    179. Wykoff CC, Khurana RN, Lampen SIR, Noronha G, Brown DM, Ou WC, Sadda SR, HULK Study Group. Suprachoroidal Triamcinolone Acetonide for Diabetic Macular Edema: The HULK Trial. Ophthalmol Retina. 2018 08; 2(8):874-877. PMID: 31047542.
      Citations: 14     Fields:    
    180. Payne JF, Clark WL, Bruce BB, Wykoff CC, Brown DM, Menke BM, Iverson SM, Allen KF, Boyer DS, Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group. Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema. Ophthalmology. 2018 08; 125(8):1304-1306. PMID: 29729809.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    181. Sultan H, Wykoff CC, Shah AR. Five-Year Outcomes of Surgically Treated Symptomatic Epiretinal Membranes With and Without Internal Limiting Membrane Peeling. Ophthalmic Surg Lasers Imaging Retina. 2018 05 01; 49(5):296-302. PMID: 29772039.
      Citations: 4     Fields:    Translation:Humans
    182. Kwon S, Wykoff CC, Brown DM, van Hemert J, Fan W, Sadda SR. Changes in retinal ischaemic index correlate with recalcitrant macular oedema in retinal vein occlusion: WAVE study. Br J Ophthalmol. 2018 08; 102(8):1066-1071. PMID: 29699979.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    183. Naik S, Wykoff CC, Ou WC, Stevenson J, Gupta S, Shah AR. Identification of factors to increase efficacy of telemedicine screening for diabetic retinopathy in endocrinology practices using the Intelligent Retinal Imaging System (IRIS) platform. Diabetes Res Clin Pract. 2018 Jun; 140:265-270. PMID: 29649538.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    184. Ou WC, Lampen SIR, Wykoff CC. Longitudinal Quantification of Retinal Nonperfusion in the Macula of Eyes With Retinal Vein Occlusion Receiving Anti-VEGF Therapy: Secondary Analysis of the WAVE Randomized Trial. Ophthalmic Surg Lasers Imaging Retina. 2018 04 01; 49(4):258-264. PMID: 29664983.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    185. Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC, Diabetic Retinopathy Clinical Research Network. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema. Ophthalmology. 2018 07; 125(7):1054-1063. PMID: 29525602; PMCID: PMC6568257.
      Citations: 13     Fields:    Translation:Humans
    186. Wykoff CC, Clark WL, Nielsen JS, Brill JV, Greene LS, Heggen CL. Optimizing Anti-VEGF Treatment Outcomes for Patients with Neovascular Age-Related Macular Degeneration. J Manag Care Spec Pharm. 2018 Feb; 24(2-a Suppl):S3-S15. PMID: 29383980; PMCID: PMC10408401.
      Citations: 33     Fields:    Translation:HumansCells
    187. Fan W, Abdelfattah NS, Uji A, Lei J, Ip M, Sadda SR, Wykoff CC, TREX-AMD Study Group. Subfoveal choroidal thickness predicts macular atrophy in age-related macular degeneration: results from the TREX-AMD trial. Graefes Arch Clin Exp Ophthalmol. 2018 Mar; 256(3):511-518. PMID: 29374796.
      Citations: 8     Fields:    Translation:Humans
    188. Brown DM, Ou WC, Wong TP, Kim RY, Croft DE, Wykoff CC, DAVE Study Group. Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion: Three-Year Randomized DAVE Trial. Ophthalmology. 2018 05; 125(5):683-690. PMID: 29336896.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    189. Burgess FR, Radwan M, Croft DE, Wykoff CC. Diagnostic and Therapeutic Challenges. Retina. 2018 Jan; 38(1):203-206. PMID: 28207611.
      Citations:    Fields:    Translation:Humans
    190. Steinle NC, Lampen SIR, Wykoff CC. The Intersection of Diabetes Mellitus and Cataract Surgery: Current State of Management. Ophthalmol Retina. 2018 02; 2(2):83-85. PMID: 31047349.
      Citations:    Fields:    Translation:Humans
    191. Sadaka A, Iqbal C, Nazari H, Berry S, Wykoff CC, Humayun MS, Lee AG. Positive Visual Phenomena Following Implantation of the Argus II Retinal Prosthesis. Ophthalmic Surg Lasers Imaging Retina. 2017 12 01; 48(12):1022-1025. PMID: 29253307.
      Citations: 1     Fields:    Translation:Humans
    192. Brown DM, Wykoff CC. Intravitreal aflibercept for proliferative diabetic retinopathy. Lancet. 2017 11 11; 390(10108):2141. PMID: 29143753.
      Citations: 1     Fields:    Translation:Humans
    193. Ling J, Wykoff CC, Ch?vez-Barrios P. Subconjunctival Silicon Oil Cysts. Ophthalmol Retina. 2017 Nov - Dec; 1(6):560. PMID: 31047453.
      Citations:    Fields:    
    194. Campochiaro PA, Wykoff CC, Brown DM, Boyer DS, Barakat M, Taraborelli D, Noronha G, Tanzanite Study Group. Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study. Ophthalmol Retina. 2018 04; 2(4):320-328. PMID: 31047241.
      Citations: 21     Fields:    
    195. Wykoff CC, Ou WC, Khurana RN, Brown DM, Lloyd Clark W, Boyer DS, ENDURANCE Study Group. Long-term outcomes with as-needed aflibercept in diabetic macular oedema: 2-year outcomes of the ENDURANCE extension study. Br J Ophthalmol. 2018 05; 102(5):631-636. PMID: 28814412.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    196. Wykoff CC, Ou WC, Croft DE, Payne JF, Brown DM, Clark WL, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial. Br J Ophthalmol. 2018 04; 102(4):460-464. PMID: 28779006.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    197. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Erratum. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care 2017;40:412-418. Diabetes Care. 2017 09; 40(9):1285. PMID: 28705833; PMCID: PMC5566277.
      Citations: 6     Fields:    
    198. Fan W, Wang K, Ghasemi Falavarjani K, Sagong M, Uji A, Ip M, Wykoff CC, Brown DM, van Hemert J, Sadda SR. Distribution of Nonperfusion Area on Ultra-widefield Fluorescein Angiography in Eyes With Diabetic Macular Edema: DAVE Study. Am J Ophthalmol. 2017 Aug; 180:110-116. PMID: 28579062.
      Citations: 29     Fields:    Translation:Humans
    199. Wykoff CC, Bansal AS, Akiyama K, Palmer JD, Chen E, Chang LK, Major JC, Wu C, Wang R, Croft DE, Wong TP, Khurana RN. THE ASSOCIATION OF EPIRETINAL MEMBRANE WITH MACULAR HOLE FORMATION AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR. Retina. 2017 Jun; 37(6):1073-1078. PMID: 27632712.
      Citations: 11     Fields:    Translation:Humans
    200. Ou WC, Brown DM, Payne JF, Wykoff CC. Relationship Between Visual Acuity and Retinal Thickness During Anti-Vascular Endothelial Growth Factor Therapy for Retinal Diseases. Am J Ophthalmol. 2017 Aug; 180:8-17. PMID: 28549848.
      Citations: 19     Fields:    Translation:Humans
    201. Wykoff CC. Impact of intravitreal pharmacotherapies including antivascular endothelial growth factor and corticosteroid agents on diabetic retinopathy. Curr Opin Ophthalmol. 2017 May; 28(3):213-218. PMID: 28376510.
      Citations: 14     Fields:    Translation:Humans
    202. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Erratum. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care 2017;40:412-418. Diabetes Care. 2017 06; 40(6):809. PMID: 28432087; PMCID: PMC5439409.
      Citations: 1     Fields:    
    203. Singh RP, Wykoff CC, Brown DM, Larsen M, Terasaki H, Silva FQ, Saroj N, Gibson A, Vitti R, Kayshap S, Berliner AJ, Zeitz O, Metzig C, Thompson D, Nguyen QD. Outcomes of Diabetic Macular Edema Patients by Baseline Hemoglobin A1c: Analyses from VISTA and VIVID. Ophthalmol Retina. 2017 Sep - Oct; 1(5):382-388. PMID: 31047565.
      Citations: 3     Fields:    
    204. Wykoff CC, Ou WC, Wang R, Brown DM, Cone C, Zamora D, Le RT, Sagong M, Wang K, Sadda SR, WAVE Study Group. Peripheral Laser for Recalcitrant Macular Edema Owing to Retinal Vein Occlusion: The WAVE Trial. Ophthalmology. 2017 06; 124(6):919-921. PMID: 28318636.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    205. Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS, ENDURANCE Study Group. Reply. Am J Ophthalmol. 2017 05; 177:236-237. PMID: 28302270.
      Citations:    Fields:    
    206. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care. 2017 03; 40(3):412-418. PMID: 28223445; PMCID: PMC5402875.
      Citations: 204     Fields:    
    207. Wykoff CC, Ou WC, Brown DM, Croft DE, Wang R, Payne JF, Clark WL, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Randomized Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: 2-Year Results of the TREX-AMD Study. Ophthalmol Retina. 2017 Jul - Aug; 1(4):314-321. PMID: 31047517.
      Citations: 29     Fields:    
    208. Wykoff CC, Marcus DM, Midena E, Saroj N, Gibson A, Vitti R, Berliner AJ, Williams Liu Z, Zeitz O, Metzig C, Schmelter T, Heier JS, Korobelnik JF. Intravitreal Aflibercept Injection in Eyes With Substantial Vision Loss After Laser Photocoagulation for Diabetic Macular Edema: Subanalysis of the VISTA and VIVID Randomized Clinical Trials. JAMA Ophthalmol. 2017 Feb 01; 135(2):107-114. PMID: 28006063.
      Citations: 2     Fields:    
    209. Witkin AJ, Chang DF, Jumper JM, Charles S, Eliott D, Hoffman RS, Mamalis N, Miller KM, Wykoff CC. Vancomycin-Associated Hemorrhagic Occlusive Retinal Vasculitis: Clinical Characteristics of 36 Eyes. Ophthalmology. 2017 05; 124(5):583-595. PMID: 28110950.
      Citations: 31     Fields:    Translation:Humans
    210. Wykoff CC, Chakravarthy U, Campochiaro PA, Bailey C, Green K, Cunha-Vaz J. Long-term Effects of Intravitreal 0.19 mg Fluocinolone Acetonide Implant on Progression and Regression of Diabetic Retinopathy. Ophthalmology. 2017 04; 124(4):440-449. PMID: 28081945.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    211. Abdelfattah NS, Al-Sheikh M, Pitetta S, Mousa A, Sadda SR, Wykoff CC, Treat-and-Extend Age-Related Macular Degeneration Study Group. Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial. Ophthalmology. 2017 02; 124(2):215-223. PMID: 27863845.
      Citations: 14     Fields:    Translation:Humans
    212. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Randomized Trial of Treat and Extend Ranibizumab with and without Navigated Laser for Diabetic Macular Edema: TREX-DME 1 Year Outcomes. Ophthalmology. 2017 01; 124(1):74-81. PMID: 27836430.
      Citations: 29     Fields:    Translation:Humans
    213. Corvi F, Lattanzio R, Miserocchi E, Querques L, Bandello F, Querques G, Croft DE, Wykoff CC. Diagnostic and Therapeutic Challenges. Retina. 2016 Nov; 36(11):2239-2245. PMID: 27322945.
      Citations:    Fields:    Translation:Humans
    214. Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS, ENDURANCE Study Group. Outcomes With As-Needed Aflibercept and Macular Laser Following the Phase III VISTA DME Trial: ENDURANCE 12-Month Extension Study. Am J Ophthalmol. 2017 Jan; 173:56-63. PMID: 27702624.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    215. Croft DE, Wykoff CC, Michels S, Chakravarthy U, Cruess AF. Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A Look Both Home and Abroad. Am J Ophthalmol. 2016 09; 169:xiv-xvi. PMID: 27485923.
      Citations:    Fields:    Translation:Humans
    216. Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC, Brown DM, Schefler AC, Kim RY, O'Malley RE, Li AL. ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul; 36(7):1349-56. PMID: 26655622.
      Citations: 7     Fields:    Translation:HumansCells
    217. Wykoff CC, Elman MJ, Regillo CD, Ding B, Lu N, Stoilov I. Predictors of Diabetic Macular Edema Treatment Frequency with Ranibizumab During the Open-Label Extension of the RIDE and RISE Trials. Ophthalmology. 2016 08; 123(8):1716-1721. PMID: 27208982.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    218. Wykoff CC, Hariprasad SM. DRCR Protocol-T: Reconciling 1- and 2-Year Data for Managing Diabetic Macular Edema. Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 01; 47(4):308-12. PMID: 27065368.
      Citations: 6     Fields:    Translation:Humans
    219. Wykoff CC, Christie L, Croft DE, Major JC, Fish RH, Brown DM, Wang R. CHOROIDAL NEOVASCULARIZATION SECONDARY TO ALEXANDRITE LASER EXPOSURE. Retin Cases Brief Rep. 2016; 10(3):244-8. PMID: 26584328.
      Citations: 4     Fields:    Translation:Humans
    220. Wykoff CC, Brown DM, Wang R. GRANULAR HYPERREFLECTIVE SPECKS BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AS SIGNS OF WEST NILE VIRUS INFECTION: THE STARDUST SIGN. Retin Cases Brief Rep. 2016; 10(4):349-53. PMID: 26674277.
      Citations:    Fields:    Translation:Humans
    221. Wykoff CC, Croft DE, Wong TP, RAVE Study Group, Brown DM. Reply: To PMID 24914476. Retina. 2015 Oct; 35(10):e61-3. PMID: 26398558.
      Citations:    Fields:    Translation:Humans
    222. Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015 Dec; 122(12):2514-22. PMID: 26391465.
      Citations: 82     Fields:    Translation:HumansCTClinical Trials
    223. Wykoff CC, Schwartz SG, Adelman RA, Brucker AJ, Flynn HW. Primary rhegmatogenous retinal detachment repair: evidence supports an individualised approach. Br J Ophthalmol. 2015 Nov; 99(11):1451-3. PMID: 26347529.
      Citations: 3     Fields:    Translation:Humans
    224. Major JC, Wykoff CC, Croft DE, Wang R, Mariani AF, Lehmann AE, Brown DM. Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration. Can J Ophthalmol. 2015 Oct; 50(5):373-7. PMID: 26455973.
      Citations: 7     Fields:    Translation:Humans
    225. Croft DE, Wykoff CC, van Hemert J, Verhoek M, Brown DM. Not All Retina Is Created Equal: Metabolic Quantification of Ultra-Widefield Images. Ophthalmology. 2015 Dec; 122(12):2580-2. PMID: 26123089.
      Citations: 2     Fields:    Translation:HumansCells
    226. Wykoff CC, Hariprasad SM. Comparing aflibercept, bevacizumab, and ranibizumab for DME: analysis of DRCR Protocol T. Ophthalmic Surg Lasers Imaging Retina. 2015 Mar; 46(3):302-5. PMID: 25835307.
      Citations: 7     Fields:    Translation:Humans
    227. Wykoff CC, Brown DM, Croft DE, Major JC, Wong TP. Progressive retinal nonperfusion in ischemic central retinal vein occlusion. Retina. 2015 Jan; 35(1):43-7. PMID: 25102193.
      Citations: 11     Fields:    Translation:Humans
    228. Silva RA, Sridhar J, Miller D, Wykoff CC, Flynn HW. Exogenous fungal endophthalmitis: an analysis of isolates and susceptibilities to antifungal agents over a 20-year period (1990-2010). Am J Ophthalmol. 2015 Feb; 159(2):257-64.e1. PMID: 25449001.
      Citations: 14     Fields:    Translation:HumansAnimals
    229. Brown DM, Wykoff CC, Wong TP, Mariani AF, Croft DE, Schuetzle KL, RAVE Study Group. Ranibizumab in preproliferative (ischemic) central retinal vein occlusion: the rubeosis anti-VEGF (RAVE) trial. Retina. 2014 Sep; 34(9):1728-35. PMID: 24914476.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    230. Campochiaro PA, Wykoff CC, Singer M, Johnson R, Marcus D, Yau L, Sternberg G. Monthly versus as-needed ranibizumab injections in patients with retinal vein occlusion: the SHORE study. Ophthalmology. 2014 Dec; 121(12):2432-42. PMID: 25060610.
      Citations: 24     Fields:    Translation:Humans
    231. Croft DE, van Hemert J, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Precise montaging and metric quantification of retinal surface area from ultra-widefield fundus photography and fluorescein angiography. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug; 45(4):312-7. PMID: 25037013.
      Citations: 30     Fields:    Translation:Humans
    232. Campochiaro PA, Wykoff CC, Shapiro H, Rubio RG, Ehrlich JS. Neutralization of vascular endothelial growth factor slows progression of retinal nonperfusion in patients with diabetic macular edema. Ophthalmology. 2014 Sep; 121(9):1783-9. PMID: 24768239.
      Citations: 64     Fields:    Translation:HumansCTClinical Trials
    233. Wykoff CC, Brown DM, Maldonado ME, Croft DE. Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial). Br J Ophthalmol. 2014 Jul; 98(7):951-5. PMID: 24518078; PMCID: PMC4078682.
      Citations: 37     Fields:    Translation:Humans
    234. Major JC, Wykoff CC, Mariani AF, Chen E, Croft DE, Brown DM. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity. Retina. 2014 Jan; 34(1):48-54. PMID: 23764967.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    235. Wykoff CC, Flynn HW, Scott IU. What is the optimal timing for rhegmatogenous retinal detachment repair? JAMA Ophthalmol. 2013 Nov; 131(11):1399-400. PMID: 24008508.
      Citations: 4     Fields:    Translation:Humans
    236. Wykoff CC, Brown DM, Croft DE, Wong TP. Two Year SAVE Outcomes: 2.0 mg ranibizumab for recalcitrant neovascular AMD. Ophthalmology. 2013 Sep; 120(9):1945-6.e1. PMID: 24001533.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    237. Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Lasers for the treatment of intraocular tumors. Lasers Med Sci. 2013 May; 28(3):1025-34. PMID: 22302638.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    238. Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani A, Wong TP, SAVE Study Group. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results. Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr; 44(2):121-6. PMID: 23510037.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    239. Mariani AF, Major JC, Brown DM, Wykoff CC, Benz MS, Kegley EN. Purtscher-like retinopathy associated with pemphigus vulgaris. Retin Cases Brief Rep. 2013; 7(4):304-6. PMID: 25383823.
      Citations:    Fields:    
    240. Bielory BP, Dubovy SR, Sinclair JC, Wykoff C, Murray TG. Pseudohypopyon as a clinical manifestation in metastatic lung carcinoma. Ophthalmic Surg Lasers Imaging. 2012 Feb 09; 43 Online:e1-4. PMID: 22320830.
      Citations: 1     Fields:    Translation:Humans
    241. Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Laser treatment for retinopathy of prematurity. Lasers Med Sci. 2013 Feb; 28(2):683-92. PMID: 22134790.
      Citations: 11     Fields:    Translation:Humans
    242. Wykoff CC, Flynn HW, Rosenfeld PJ. Prophylaxis for endophthalmitis following intravitreal injection: antisepsis and antibiotics. Am J Ophthalmol. 2011 Nov; 152(5):717-9.e2. PMID: 22017840.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    243. Lingappan A, Wykoff CC, Albini TA, Miller D, Pathengay A, Davis JL, Flynn HW. Endogenous fungal endophthalmitis: causative organisms, management strategies, and visual acuity outcomes. Am J Ophthalmol. 2012 Jan; 153(1):162-6.e1. PMID: 21917234.
      Citations: 67     Fields:    Translation:HumansAnimals
    244. Wykoff CC, Murray TG, Markoe AM, Feun LG, Schefler AC, Gayer S. Preoperative evaluation for patients with choroidal/ciliary body melanomas: what is necessary? Am J Ophthalmol. 2011 Jun; 151(6):921-4. PMID: 21616209.
      Citations: 1     Fields:    Translation:Humans
    245. Wykoff CC, Flynn HW. Endophthalmitis after intravitreal injection: prevention and management. Retina. 2011 Apr; 31(4):633-5. PMID: 21836399.
      Citations: 4     Fields:    Translation:HumansCells
    246. Wykoff CC, Houston SK, Berrocal AM. Anti-vascular endothelial growth factor agents for pediatric retinal diseases. Int Ophthalmol Clin. 2011; 51(1):185-99. PMID: 21139484.
      Citations:    Fields:    Translation:Humans
    247. Wykoff CC, Flynn HW, Han DP. Allergy to povidone-iodine and cephalosporins: the clinical dilemma in ophthalmic use. Am J Ophthalmol. 2011 Jan; 151(1):4-6. PMID: 21163372.
      Citations: 6     Fields:    Translation:Humans
    248. Wykoff CC, Parrott MB, Flynn HW, Shi W, Miller D, Alfonso EC. Nosocomial acute-onset postoperative endophthalmitis at a university teaching hospital (2002-2009). Am J Ophthalmol. 2010 Sep; 150(3):392-398.e2. PMID: 20619391.
      Citations: 28     Fields:    Translation:Humans
    249. Wykoff CC, Smiddy WE, Mathen T, Schwartz SG, Flynn HW, Shi W. Fovea-sparing retinal detachments: time to surgery and visual outcomes. Am J Ophthalmol. 2010 Aug; 150(2):205-210.e2. PMID: 20541738.
      Citations: 12     Fields:    Translation:Humans
    250. Wykoff CC, Berrocal AM, Schefler AC, Uhlhorn SR, Ruggeri M, Hess D. Intraoperative OCT of a full-thickness macular hole before and after internal limiting membrane peeling. Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb; 41(1):7-11. PMID: 20128563.
      Citations: 17     Fields:    Translation:Humans
    251. Sisk RA, Wykoff CC, Albini TA. Comment on "fundus autofluorescence and multiple evanescent white dot syndrome". Retina. 2009 Oct; 29(9):1377-8; author reply 1378-9. PMID: 19934830.
      Citations:    Fields:    Translation:Humans
    252. Wykoff CC, Albini TA, Couvillion SS, Dubovy SR, Davis JL. Intraocular cryptococcoma. Arch Ophthalmol. 2009 May; 127(5):700-2. PMID: 19433726.
      Citations: 2     Fields:    Translation:HumansAnimals
    253. Wykoff CC, Tutiven JL, Schaefer AM, Murray TG, Couvillion SS. Diffuse neonatal hemangiomatosis presenting as bilateral iris hemangiomas in an infant. Retin Cases Brief Rep. 2009; 3(3):279-82. PMID: 25389584.
      Citations:    Fields:    
    254. Dubovy SR, Barredo JC, Murray TG, Wykoff CC. Simultaneous presentation of retinoblastoma and morning glory disk anomaly. Retin Cases Brief Rep. 2009; 3(4):354-7. PMID: 25389845.
      Citations:    Fields:    
    255. Wykoff CC, Lujan BJ, Rosenfeld PJ. Photodynamic therapy of bullous central serous chorioretinopathy with subretinal exudate and a tear of the retinal pigment epithelium. Retin Cases Brief Rep. 2009; 3(2):218-23. PMID: 25391081.
      Citations: 2     Fields:    
    256. Wykoff CC, Lam BL, Brathwaite CD, Biegel JA, McKeown CA, Rosenblum MK, Allewelt HB, Sandberg DI. Atypical teratoid/rhabdoid tumor arising from the third cranial nerve. J Neuroophthalmol. 2008 Sep; 28(3):207-11. PMID: 18769285; PMCID: PMC2839362.
      Citations: 6     Fields:    Translation:Humans
    257. Wykoff CC, Flynn HW, Miller D, Scott IU, Alfonso EC. Exogenous fungal endophthalmitis: microbiology and clinical outcomes. Ophthalmology. 2008 Sep; 115(9):1501-7, 1507.e1-2. PMID: 18486220.
      Citations: 47     Fields:    Translation:HumansAnimals
    258. Wykoff CC, Pineda R. Myopic laser in situ keratomileusis in eyes with thick corneas. J Cataract Refract Surg. 2006 May; 32(5):900-1. PMID: 16765817.
      Citations:    Fields:    Translation:Humans
    259. Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. J Biol Chem. 2004 Oct 08; 279(41):42719-25. PMID: 15302861.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    260. Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. J Pathol. 2004 Jul; 203(3):808-13. PMID: 15221940.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    261. Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol. 2003 Jun; 200(2):222-8. PMID: 12754744.
      Citations: 32     Fields:    Translation:Humans
    262. Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol. 2003 Feb 01; 21(3):473-82. PMID: 12560438.
      Citations: 105     Fields:    Translation:HumansCells
    263. Adeyinka A, Emberley E, Niu Y, Snell L, Murphy LC, Sowter H, Wykoff CC, Harris AL, Watson PH. Analysis of gene expression in ductal carcinoma in situ of the breast. Clin Cancer Res. 2002 Dec; 8(12):3788-95. PMID: 12473591.
      Citations: 25     Fields:    Translation:HumansCells
    264. Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 2002 Jun; 1(5):459-68. PMID: 12124175.
      Citations: 221     Fields:    Translation:Humans
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