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CHARLES WYKOFF

TitleClinical Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Ophthalmology
Address6560 Fannin, Suite 750
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chaudhary V, Mar F, Amador MJ, Chang A, Gibson K, Joussen AM, Kim JE, Lee J, Margaron P, Saffar I, Wong D, Wykoff C, Sadda S. Emerging clinical evidence of a dual role for Ang-2 and VEGF-A blockade with faricimab in retinal diseases. Graefes Arch Clin Exp Ophthalmol. 2024 Dec 21. PMID: 39708087.
      Citations:    Fields:    
    2. Darzi AJ, Busse JW, Torabiardakani K, Phillips M, Thabane L, Bhandari M, Borrelli E, Steel DH, Wykoff CC, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Risk assessment models: considerations prior to use in clinical practice. Eye (Lond). 2024 Dec 18. PMID: 39695254.
      Citations:    Fields:    
    3. Tao BK, Huang RS, Mihalache A, Hwang J, Issa M, Naidu S, Popovic MM, Wykoff CC, McKay B, Kertes PJ, Yan P, Wong DT, Kohly RP, Muni RH. Endophthalmitis After Bilateral Same-Day vs Unilateral Intravitreal Injection. Ophthalmol Retina. 2024 Dec 16. PMID: 39694278.
      Citations:    Fields:    
    4. Fan KC, Wong CW, Nichols BA, Sadat R, Becker TC, Brown DM, Wykoff CC. Distinguishing ABCA4 from PRPH2-related disease: qualitative analysis of examination and imaging features. Ophthalmic Genet. 2024 Nov 25; 1-7. PMID: 39586833.
      Citations:    Fields:    
    5. Nanji K, Phillips M, Thabane L, Tham YC, Wong TY, Steel DH, Munk MR, Wykoff CC, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Pilot and feasibility studies in ophthalmology: fundamental keys to success. Eye (Lond). 2025 Jan; 39(1):4-6. PMID: 39572846; PMCID: PMC11733216.
      Citations:    Fields:    
    6. Newman D, Warren B, Barker R, Wykoff CC, Vujosevic S. Patient and Physician Perspectives of Diabetic Retinopathy and Diabetic Macular Edema Diagnosis, Treatment and Progression: A Podcast Article. Ophthalmol Ther. 2025 Jan; 14(1):1-12. PMID: 39503993; PMCID: PMC11724807.
      Citations:    
    7. Nouri N, Gussler BH, Stockwell A, Truong T, Kang GJ, Browder KC, Malato Y, Sene A, Van Everen S, Wykoff CC, Brown D, Fu A, Palmer JD, Lima de Carvalho JR, Ullah E, Al Rawi R, Chew EY, Zein WM, Guan B, McCarthy MI, Hofmann JW, Chaney SY, Jasper H, Yaspan BL. SLC16A8 is a causal contributor to age-related macular degeneration risk. NPJ Genom Med. 2024 Oct 28; 9(1):50. PMID: 39468037; PMCID: PMC11519927.
      Citations:    
    8. Pecaku A, Melo IM, Cao JA, Sabour S, Naidu SC, Demian S, Popovic MM, Wykoff CC, Govetto A, Muni RH, Cao JA, Demian S, Wykoff CC. Morphologic Stages of Full-Thickness Macular Hole on Spectral-Domain OCT. Ophthalmol Retina. 2024 Oct 24. PMID: 39461424.
      Citations:    Fields:    
    9. Wykoff CC, Do DV, Clark WL, Boyer DS, Dhoot DS, Marcus DM, Vitti R, Berliner AJ, Reed K, Cheng Y, Moini H, Brown DM. Longitudinal Changes in Diabetic Retinopathy Severity: Learnings from PANORAMA. Ophthalmol Retina. 2025 Jan; 9(1):91-94. PMID: 39424059.
      Citations:    Fields:    
    10. Avram O, Durmus B, Rakocz N, Corradetti G, An U, Nittala MG, Terway P, Rudas A, Chen ZJ, Wakatsuki Y, Hirabayashi K, Velaga S, Tiosano L, Corvi F, Verma A, Karamat A, Lindenberg S, Oncel D, Almidani L, Hull V, Fasih-Ahmad S, Esmaeilkhanian H, Cannesson M, Wykoff CC, Rahmani E, Arnold CW, Zhou B, Zaitlen N, Gronau I, Sankararaman S, Chiang JN, Sadda SR, Halperin E. Accurate prediction of disease-risk factors from volumetric medical scans by a deep vision model pre-trained with 2D scans. Nat Biomed Eng. 2024 Oct 01. PMID: 39354052.
      Citations:    Fields:    
    11. Ferro Desideri L, Sim PY, Bernardi E, Paschon K, Roth J, Fung AT, Wu XN, Chou HD, Henderson R, Tsui E, Berrocal M, Chhablani J, Wykoff CC, Cheung CMG, Querques G, Melo GB, Subhi Y, Loewenstein A, Kiilgaard JF, Zinkernagel M, Anguita R. Evidence-based guidelines for drug dosing in intravitreal injections in silicone oil-filled eyes: Pharmacokinetics, safety, and optimal dosage. Surv Ophthalmol. 2025 Jan-Feb; 70(1):96-105. PMID: 39343316.
      Citations:    Fields:    Translation:Humans
    12. Amram AL, Whitmore SS, Wang C, Clavell C, Lyons LJ, Rusakevich AM, Han I, Folk J, Boldt HC, Stone EM, Russell SR, Lee K, Abramoff M, Wykoff C, Sohn EH. Progressive inner retinal neurodegeneration in non-proliferative macular telangiectasia type 2. Br J Ophthalmol. 2024 Sep 17. PMID: 39288977.
      Citations:    Fields:    
    13. Brown DM, Jaffe GJ, Wykoff CC, Adiguzel E, Heier JS, Khanani AM, Brown DM, Jaffe GJ, Wykoff CC, Adiguzel E, Heier JS, Khanani AM. MERLIN: Two-Year Results of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid. Ophthalmology. 2024 Sep 07. PMID: 39182627.
      Citations: 2     Fields:    
    14. Al-Khersan H, Garcia E, Fan KC, Staropoli PC, Wood EH, Storey P, Adam MK, Parke DW, Halperin LS, Quinn K, Wykoff C, Al-Khersan H, Garcia E, Fan KC, Staropoli PC, Wood EH, Storey P, Adam MK, Parke DW, Halperin LS, Quinn K, Wykoff CC. Impact of a Recall of Intravitreal Bevacizumab: a Health Analytics in Ophthalmology Registry Review. Ophthalmol Retina. 2024 Dec; 8(12):1211-1213. PMID: 39233226.
      Citations:    Fields:    
    15. Korobelnik JF, Lanzetta P, Wykoff CC, Wong TY, Zhang X, Morgan-Warren P, Fitzpatrick S, Leal S, Brunck L, Hasanbasic Z, Chu KW, Reed K, Sivaprasad S. Sustained disease control with aflibercept 8 mg: a new benchmark in the management of retinal neovascular diseases. Eye (Lond). 2024 Dec; 38(17):3218-3221. PMID: 39217260; PMCID: PMC11584797.
      Citations:    Fields:    
    16. Wykoff CC, Kuppermann BD, Regillo CD, Chang M, Hariprasad SM, Duker JS, Altaf S, Sa?m S. Extended Intraocular Drug-Delivery Platforms for the Treatment of Retinal and Choroidal Diseases. J Vitreoretin Dis. 2024 Sep-Oct; 8(5):577-586. PMID: 39318989; PMCID: PMC11418737.
      Citations:    
    17. Mahmoudi A, Manafi N, Corradetti G, Gupta Nittala M, Emamverdi M, Trejo Corona S, Wykoff CC, Sarraf D, Sadda SR. Risk factors for development of hyper-reflective foci overlying drusen in eyes with intermediate age-related macular degeneration. Br J Ophthalmol. 2024 Aug 22; 108(9):1234-1239. PMID: 38325906.
      Citations: 1     Fields:    Translation:Humans
    18. Ashrafkhorasani M, Habibi A, Nittala MG, Yaseri M, Emamverdi M, Velaga SB, Wykoff CC, Ciulla TA, Ip M, Sadda SR. Spectral-domain OCT characteristics of intraretinal hyper-reflective foci associated with age-related macular degeneration and diabetic retinopathy. Can J Ophthalmol. 2024 Aug 08. PMID: 39128832.
      Citations:    Fields:    
    19. Rasmussen MLR, Cehofski LJ, Davies J, Faber C, Falk MK, Grauslund J, Hansen MS, Keane PA, Natarajan S, Peto T, Subhi Y, Wykoff CC, Muttuvelu DV. The Impact of the COVID-19 Pandemic on Tele-ophthalmology-Based Retinal Screening. Ophthalmol Ther. 2024 Sep; 13(9):2467-2480. PMID: 39093386; PMCID: PMC11341501.
      Citations:    
    20. Brown DM, Laswell SM, Rahman EZ, Fan KC, Shah A, Patel SB, Wykoff CC. CLINICALLY RELEVANT POSTERIOR VITREOUS DETACHMENT STAGING USING CIRCUMPAPILLARY AND MACULAR VOLUME OPTICAL COHERENCE TOMOGRAPHY. Retina. 2024 08 01; 44(8):1441-1448. PMID: 39047131; PMCID: PMC11280448.
      Citations:    Fields:    Translation:HumansCells
    21. Dang S, Parke DW, Sodhi GS, Eichenbaum D, Nielsen J, Danzig C, Lalwani G, Moinfar N, London N, Kimura A, Jumper JM, Lord K, Sheth V, Pieramici D, Orlin A, Madson A, Horton M, Blim J, Cao JA, Thompson J, Khanna S, Wykoff CC, Shah AR. Anti-VEGF Pharmaceutical Prior Authorization in Retina Practices. JAMA Ophthalmol. 2024 Aug 01; 142(8):716-721. PMID: 38935350; PMCID: PMC11211988.
      Citations:    Fields:    Translation:Humans
    22. Barakat MR, Brown D, Hu A, Khurana RN, Marcus D, Pearlman J, Wykoff CC, Kapik B, Ciulla T. Safety and Tolerability of Suprachoroidal Axitinib Injectable Suspension, for Neovascular Age-related Macular Degeneration; Phase I/IIa Open-Label, Dose-Escalation Trial. Ophthalmol Sci. 2025 Jan-Feb; 5(1):100586. PMID: 39328827; PMCID: PMC11426123.
      Citations:    
    23. Nanji K, Xie J, Hatamnejad A, Pur DR, Phillips M, Zeraatkar D, Wong TY, Guymer RH, Kaiser PK, Sivaprasad S, Bhandari M, Steel DH, Wykoff CC, Chaudhary V. Exploring the fragility of meta-analyses in ophthalmology: a systematic review. Eye (Lond). 2024 Nov; 38(16):3153-3160. PMID: 39033242; PMCID: PMC11543934.
      Citations: 1     Fields:    Translation:Humans
    24. Nanji K, Kennedy K, Fung M, Xie J, Hatamnejad A, Garg SJ, Wykoff CC, Chaudhary V. Impact of COVID-19 on a real-world treat-and-extend regimen with aflibercept for neovascular age-related macular degeneration. Can J Ophthalmol. 2024 Jul 19. PMID: 39033785.
      Citations:    Fields:    
    25. Richards K, Kadakia A, Wykoff CC, Major JC, Wong TP, Chen E, Schefler AC, Patel SB, Kim RY, Henry CR, Fish RH, Brown DM, Benz MS, Pearce W, Shah AR. MANAGEMENT OF LARGE FULL-THICKNESS MACULAR HOLES: Long-Term Outcomes of Internal Limiting Membrane Flaps and Internal Limiting Membrane Peels. Retina. 2024 07 01; 44(7):1165-1170. PMID: 38900578.
      Citations:    Fields:    Translation:HumansCells
    26. Wykoff CC, Lad EM, Heier JS. Syfovre Approval for Geographic Atrophy. JAMA Ophthalmol. 2024 Jul 01; 142(7):685-686. PMID: 38814626.
      Citations:    Fields:    Translation:Humans
    27. Cao JA, Al-Khersan H, Chaudhary V, Wykoff CC. Correction: Retinal non-perfusion: recognizing and defining what is important. Eye (Lond). 2024 Jun; 38(9):1782. PMID: 38548947; PMCID: PMC11156645.
      Citations:    Fields:    
    28. Wykoff CC, Avery RL, Barakat MR, Boyer DS, Brown DM, Brucker AJ, Cunningham ET, Heier JS, Holekamp NM, Kaiser PK, Khanani AM, Kim JE, Demirci H, Regillo CD, Yiu G, Ciulla TA, Wykoff CC, Avery RL, Barakat MR, Boyer DS, Brown DM, Brucker AJ, Cunningham ET, Heier JS, Holekamp NM, Kaiser PK, Khanani AM, Kim JE, Demirci H, Regillo CD, Yiu GC, Ciulla TA. SUPRACHOROIDAL SPACE INJECTION TECHNIQUE: Expert Panel Guidance. Retina. 2024 06 01; 44(6):939-949. PMID: 38451179.
      Citations: 1     Fields:    Translation:Humans
    29. Trejo Corona S, Parvus MN, Fan KC, Patel SB, Lane RG, Flynn HW, Wykoff CC. Open-Globe Injury With Globe Penetration Leading to Complex Retinal Detachment After Intraoral Anesthetic Injection. J Vitreoretin Dis. 2024 Jul-Aug; 8(4):480-484. PMID: 39148572; PMCID: PMC11323522.
      Citations:    
    30. Huang Y, Choo C, Hancock S, Ciulla TA, Wykoff CC, Shantha JG, Yeh S. Suprachoroidal Drug Delivery for Macular Edema Associated With Noninfectious Uveitis. J Vitreoretin Dis. 2024 Jul-Aug; 8(4):401-409. PMID: 39148567; PMCID: PMC11323513.
      Citations: 1     
    31. Lindenberg S, Mahmoudi A, Oncel D, Corradetti G, Oncel D, Emamverdi M, Almidani L, Farahani A, Wakatsuki Y, He Y, Saju M S, Lee WK, Wykoff CC, Sarraf D, Freund KB, Sadda SR. Acquired Vitelliform Lesions in Intermediate Age-Related Macular Degeneration: A Cross Sectional Study. Ophthalmol Retina. 2024 Sep; 8(9):854-862. PMID: 38631656.
      Citations:    Fields:    Translation:Humans
    32. Mahmoudi A, Lindenberg S, Corradetti G, Emamverdi M, Oncel D, Oncel D, Baek J, Farahani A, Almidani L, He Y, Abbasgholizadeh R, Saju SM, Lee WK, Wykoff CC, Sarraf D, Freund KB, Sadda SR, Lee WK, Wykoff CC, Freund KB. Predictive Factors Influencing the Evolution of Acquired Vitelliform Lesions in Intermediate Age-Related Macular Degeneration Eyes. Ophthalmol Retina. 2024 Sep; 8(9):863-871. PMID: 38599379.
      Citations:    Fields:    Translation:Humans
    33. Campochiaro PA, Avery R, Brown DM, Heier JS, Ho AC, Huddleston SM, Jaffe GJ, Khanani AM, Pakola S, Pieramici DJ, Wykoff CC, Van Everen S. Gene therapy for neovascular age-related macular degeneration by subretinal delivery of RGX-314: a phase 1/2a dose-escalation study. Lancet. 2024 Apr 20; 403(10436):1563-1573. PMID: 38554726.
      Citations: 11     Fields:    Translation:HumansCTClinical Trials
    34. Hartnett ME, Fickweiler W, Adamis AP, Brownlee M, Das A, Duh EJ, Feener EP, King G, Kowluru R, Luhmann UFO, Storti F, Wykoff CC, Aiello LP. Rationale of Basic and Cellular Mechanisms Considered in Updating the Staging System for Diabetic Retinal Disease. Ophthalmol Sci. 2024 Sep-Oct; 4(5):100521. PMID: 39006804; PMCID: PMC11245984.
      Citations: 1     
    35. Zarbin MA, MacCumber MW, Karcher H, Adiguzel E, Mayhook A, LaPrise A, Bilano VL, Igwe F, Ip MS, Wykoff CC. Real-World Safety Outcomes with Brolucizumab in Neovascular Age-Related Macular Degeneration: Findings from the IRIS? Registry. Ophthalmol Ther. 2024 May; 13(5):1357-1368. PMID: 38520643; PMCID: PMC11039576.
      Citations:    
    36. Brown DM, Boyer DS, Do DV, Wykoff CC, Sakamoto T, Win P, Joshi S, Salehi-Had H, Seres A, Berliner AJ, Leal S, Vitti R, Chu KW, Reed K, Rao R, Cheng Y, Sun W, Voronca D, Bhore R, Schmidt-Ott U, Schmelter T, Schulze A, Zhang X, Hirshberg B, Yancopoulos GD, Sivaprasad S, PHOTON Investigators. Intravitreal aflibercept 8 mg in diabetic macular oedema (PHOTON): 48-week results from a randomised, double-masked, non-inferiority, phase 2/3 trial. Lancet. 2024 Mar 23; 403(10432):1153-1163. PMID: 38461843.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    37. Cao JA, Al-Khersan H, Chaudhary V, Wykoff CC. Retinal non-perfusion: recognizing and defining what is important. Eye (Lond). 2024 Jun; 38(9):1608-1609. PMID: 38438795; PMCID: PMC11156853.
      Citations:    Fields:    Translation:Humans
    38. Zeraatkar D, Pitre T, Phillips M, Steel DH, Wykoff CC, Wong TY, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. The ophthalmologist's guide to evaluating the certainty of evidence using the GRADE approach. Eye (Lond). 2024 Jun; 38(9):1601-1604. PMID: 38316973; PMCID: PMC11156871.
      Citations: 1     Fields:    Translation:Humans
    39. Manafi N, Mahmoudi A, Emamverdi M, Corradetti G, Corona ST, Wykoff CC, Sadda SR. Topographic analysis of local OCT biomarkers which predict progression to atrophy in age-related macular degeneration. Graefes Arch Clin Exp Ophthalmol. 2024 Jul; 262(7):2083-2091. PMID: 38300334; PMCID: PMC11222249.
      Citations: 1     Fields:    Translation:Humans
    40. Shah M, Albini T, Nguyen Q, Wykoff C, Barakat M, Kapik B, Ciulla TA, Khurana RN. Safety and Efficacy of CLS-TA by Anatomic Location of Inflammation: Results from the Phase 3 PEACHTREE Clinical Trial. Ocul Immunol Inflamm. 2024 Oct; 32(8):1556-1563. PMID: 38194432.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    41. Cao JA, Dubovy SR, Fan KC, Parvus MN, Fortun JA, Wykoff CC. Free-Floating Pigmented Vitreous Cysts: Clinical-Histopathologic Correlation. Ophthalmic Surg Lasers Imaging Retina. 2024 Jan; 55(1):55-58. PMID: 38189800.
      Citations:    Fields:    Translation:Humans
    42. Eter N, Murata T, Ruamviboonsuk P, Schlottmann PG, Seres AI, Sun X, Yoon YH, YOSEMITE and RHINE Investigators, Wong TY, Haskova Z, Asik K, Baumal CR, Csaky KG, Ives JA, Jaffe GJ, Korobelnik JF, Lin H, Silverman D, Tang Y, Wells JA, Wykoff CC. Faricimab Treat-and-Extend for Diabetic Macular Edema: Two-Year Results from the Randomized Phase 3 YOSEMITE and RHINE Trials. Ophthalmology. 2024 Jun; 131(6):708-723. PMID: 38158159.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    43. Khanani AM, Boyer DS, Wykoff CC, Regillo CD, Busbee BG, Pieramici D, Danzig CJ, Joondeph BC, Major JC, Turpcu A, Kiss S. Safety and efficacy of ixoberogene soroparvovec in neovascular age-related macular degeneration in the United States (OPTIC): a prospective, two-year, multicentre phase 1 study. EClinicalMedicine. 2024 Jan; 67:102394. PMID: 38152412; PMCID: PMC10751837.
      Citations: 8     
    44. Singh RP, Barakat MR, Ip MS, Wykoff CC, Eichenbaum DA, Joshi S, Warrow D, Sheth VS, Stefanickova J, Kim YS, He F, Cho GE, Wang Y, Emanuelli A. Efficacy and Safety of Brolucizumab for Diabetic Macular Edema: The KINGFISHER Randomized Clinical Trial. JAMA Ophthalmol. 2023 Dec 01; 141(12):1152-1160. PMID: 37971723.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    45. Patel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Correction: Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 Dec; 37(17):3705. PMID: 37237234; PMCID: PMC10686405.
      Citations: 1     Fields:    
    46. Garg A, Nanji K, Tai F, Phillips M, Zeraatkar D, Garg SJ, Sadda SR, Kaiser PK, Guymer RH, Sivaprasad S, Wykoff CC, Chaudhary V. The effect of complement C3 or C5 inhibition on geographic atrophy secondary to age-related macular degeneration: A living systematic review and meta-analysis. Surv Ophthalmol. 2024 May-Jun; 69(3):349-361. PMID: 38008405.
      Citations: 1     Fields:    
    47. Avram O, Durmus B, Rakocz N, Corradetti G, An U, Nitalla MG, Rudas A, Wakatsuki Y, Hirabayashi K, Velaga S, Tiosano L, Corvi F, Verma A, Karamat A, Lindenberg S, Oncel D, Almidani L, Hull V, Fasih-Ahmad S, Esmaeilkhanian H, Wykoff CC, Rahmani E, Arnold CW, Zhou B, Zaitlen N, Gronau I, Sankararaman S, Chiang JN, Sadda SR, Halperin E. SLIViT: a general AI framework for clinical-feature diagnosis from limited 3D biomedical-imaging data. Res Sq. 2023 Nov 21. PMID: 38045283; PMCID: PMC10690310.
      Citations:    
    48. Wykoff CC, Garmo V, Tabano D, Menezes A, Kim E, Fevrier HB, LaPrise A, Leng T. Impact of Anti-VEGF Treatment and Patient Characteristics on Vision Outcomes in Neovascular Age-related Macular Degeneration: Up to 6-Year Analysis of the AAO IRIS? Registry. Ophthalmol Sci. 2024 Mar-Apr; 4(2):100421. PMID: 38187126; PMCID: PMC10767511.
      Citations: 1     
    49. Wykoff CC, Do DV, Goldberg RA, Dhoot DS, Lim JI, Du W, Silva FQ, Desai R, Moini H, Reed K, Berliner AJ, Vitti R, Clark WL. Ocular and Systemic Risk Factors for Disease Worsening Among Patients with NPDR: Post Hoc Analysis of the PANORAMA Trial. Ophthalmol Retina. 2023 Oct 27. PMID: 39491132.
      Citations:    Fields:    
    50. Nanji K, Yu CW, Wong TY, Sivaprasad S, Steel DH, Wykoff CC, Chaudhary V. Evaluation of postoperative ophthalmology patient instructions from ChatGPT and Google Search. Can J Ophthalmol. 2024 Feb; 59(1):e69-e71. PMID: 37884271.
      Citations:    Fields:    Translation:Humans
    51. Heier JS, Lad EM, Holz FG, Rosenfeld PJ, Guymer RH, Boyer D, Grossi F, Baumal CR, Korobelnik JF, Slakter JS, Waheed NK, Metlapally R, Pearce I, Steinle N, Francone AA, Hu A, Lally DR, Deschatelets P, Francois C, Bliss C, Staurenghi G, Mon?s J, Singh RP, Ribeiro R, Wykoff CC, OAKS and DERBY study investigators. Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials. Lancet. 2023 10 21; 402(10411):1434-1448. PMID: 37865470.
      Citations: 9     Fields:    Translation:HumansCTClinical Trials
    52. Patel SB, Heier JS, Chaudhary V, Wykoff CC. Treatment of geographic atrophy: an update on data related to pegcetacoplan. Curr Opin Ophthalmol. 2024 Jan 01; 35(1):64-72. PMID: 37815317.
      Citations: 1     Fields:    Translation:Humans
    53. Tai F, Nanji K, Garg A, Zeraatkar D, Phillips M, Steel DH, Garg SJ, Kaiser PK, Guymer RH, Sivaprasad S, Chaudhary V, Wykoff CC. Subthreshold Compared with Threshold Macular Photocoagulation for Diabetic Macular Edema: A Systematic Review and Meta-Analysis. Ophthalmol Retina. 2024 Mar; 8(3):223-233. PMID: 37805099.
      Citations:    Fields:    Translation:Humans
    54. Singh RP, Amoaku W, Bandello F, Chen FK, Holz FG, Kodjikian L, Ruiz-Moreno JM, Joshi P, Wykoff CC. Diagnosis and Management of Patients With Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Delphi Consensus Exercise. Ophthalmic Surg Lasers Imaging Retina. 2023 10; 54(10):589-598. PMID: 37847167.
      Citations: 1     Fields:    Translation:Humans
    55. Kalra G, Wykoff C, Martin A, Srivastava SK, Reese J, Ehlers JP. Longitudinal Quantitative Ultrawidefield Angiographic Features in Diabetic Retinopathy Treated with Aflibercept from the Intravitreal Aflibercept as Indicated by Real-Time Objective Imaging to Achieve Diabetic Retinopathy Improvement Trial. Ophthalmol Retina. 2024 Feb; 8(2):116-125. PMID: 37696393; PMCID: PMC10872550.
      Citations:    Fields:    Translation:Humans
    56. Khanani AM, Patel SS, Staurenghi G, Tadayoni R, Danzig CJ, Eichenbaum DA, Hsu J, Wykoff CC, Heier JS, Lally DR, Mon?s J, Nielsen JS, Sheth VS, Kaiser PK, Clark J, Zhu L, Patel H, Tang J, Desai D, Jaffe GJ, GATHER2 trial investigators. Efficacy and safety of avacincaptad pegol in patients with geographic atrophy (GATHER2): 12-month results from a randomised, double-masked, phase 3 trial. Lancet. 2023 Oct 21; 402(10411):1449-1458. PMID: 37696275.
      Citations: 5     Fields:    
    57. Kokilepersaud K, Corona ST, Prabhushankar M, AlRegib G, Wykoff C. Clinically Labeled Contrastive Learning for OCT Biomarker Classification. IEEE J Biomed Health Inform. 2023 09; 27(9):4397-4408. PMID: 37216249.
      Citations:    Fields:    Translation:Humans
    58. Chen SN, Chou HD, Lai CC, Mahgoub MM, Matoba R, Morizane Y, Nehemy MB, Park JG, Adrean SD, Begaj T, Capone A, Charles S, Cohen MN, Corona ST, Faia LJ, Garg SJ, Garretson BR, Gregori NZ, Haller JA, Houghton OM, Hsu J, Jo J, Kaiser RS, Mansoor M, Raphaelian PV, Regillo CD, Ruby AJ, Runner MM, Sneed SR, Sohn EH, Spirn MJ, Vander JF, Wakabayashi T, Wolfe JD, Wykoff CC, Yonekawa Y, Yoon YH, Mahmoud TH. Surgical Management of Full-Thickness Macular Holes in Macular Telangiectasia Type 2: A Global Multicenter Study. Ophthalmology. 2024 Jan; 131(1):66-77. PMID: 37661066.
      Citations:    Fields:    Translation:Humans
    59. Wykoff CC, Brown DM, Reed K, Berliner AJ, Gerstenblith AT, Breazna A, Abraham P, Fein JG, Chu KW, Clark WL, Leal S, Schmelter T, Hirshberg B, Yancopoulos GD, Vitti R, CANDELA Study Investigators. Effect of High-Dose Intravitreal Aflibercept, 8 mg, in Patients With Neovascular Age-Related Macular Degeneration: The Phase 2 CANDELA Randomized Clinical Trial. JAMA Ophthalmol. 2023 09 01; 141(9):834-842. PMID: 37535382.
      Citations: 5     Fields:    Translation:Humans
    60. Louis AM, Ali AM, Patel SB, Fan KC, Rahman EZ, Pearce WA, Trejo Corona S, Villanueva Boone C, Yu HJ, Wykoff CC. Impact of Prefilled Syringes and Masking on Postintravitreal Injection Endophthalmitis. J Vitreoretin Dis. 2023 Sep-Oct; 7(5):382-388. PMID: 37706081; PMCID: PMC10496810.
      Citations:    
    61. Salabati M, Huang C, Kamalipour A, Yu HJ, Mahmoudzadeh R, Jeng-Miller K, Chen E, Shah CP, Wykoff CC, Hsu J. Magnitude of Visual Acuity Change with ETDRS versus Snellen Testing in Clinical Trials: Implications for Clinic-Based Outcomes. Ophthalmol Sci. 2024 Mar-Apr; 4(2):100372. PMID: 37868803; PMCID: PMC10587620.
      Citations: 1     
    62. Wykoff CC, Garweg JG, Regillo C, Souied E, Wolf S, Dhoot DS, Agostini HT, Chang A, Laude A, Wachtlin J, Kovacic L, Wang L, Wang Y, Bouillaud E, Brown DM. KESTREL and KITE Phase 3 Studies: 100-Week Results With Brolucizumab in Patients With Diabetic Macular Edema. Am J Ophthalmol. 2024 04; 260:70-83. PMID: 37460036.
      Citations: 3     Fields:    Translation:Humans
    63. Yu CW, Nanji K, Hatamnejad A, Gemae M, Joarder I, Achunair A, Devji T, Phillips M, Zeraatkar D, Guymer RH, Chaudhary V, Steel DH, Sivaprasad S, Wykoff CC. Patient-Reported Outcome Measure Use in Guidelines Published by the American Academy of Ophthalmology: A Review. Ophthalmology. 2023 Nov; 130(11):1201-1211. PMID: 37429499.
      Citations:    Fields:    
    64. Grewal DS, Wykoff CC, D'Souza D, Jehl V, Alecu I, Jaffe GJ. Imaging Features of Retinal Vasculitis and/or Retinal Vascular Occlusion after Brolucizumab Treatment in the Postmarketing Setting. Ophthalmol Sci. 2024 Jan-Feb; 4(1):100361. PMID: 37869023; PMCID: PMC10587630.
      Citations:    
    65. Matsumoto H, Karcher H, Mayhook A, Oshagbemi OA, Zorina O, Wykoff CC, Barakat MR, Lozama A, Hassan TS, Khanani AM, Heier JS. RETINAL VASCULITIS OR VASCULAR OCCLUSION AFTER BROLUCIZUMAB FOR NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Systematic Review of Real-World Evidence. Retina. 2023 07 01; 43(7):1051-1063. PMID: 36893438; PMCID: PMC10278563.
      Citations: 2     Fields:    Translation:Humans
    66. Hatamnejad A, Dadak R, Orr S, Wykoff C, Choudhry N. Systematic review of efficacy and meta-analysis of safety of ranibizumab biosimilars relative to reference ranibizumab anti-VEGF therapy for nAMD treatment. BMJ Open Ophthalmol. 2023 06; 8(1). PMID: 37493655; PMCID: PMC10277130.
      Citations: 1     Fields:    Translation:Humans
    67. Peng ET, Parvus MN, Yu HJ, Laswell SM, Pearce WA, Fan KC, Major JC, Brown DM, Wykoff CC, Patel SB. Risk Factors for the Development of Fellow Eye Horseshoe Retinal Tears Following Horseshoe Retinal Tear in the Presenting Eye. Ophthalmic Surg Lasers Imaging Retina. 2023 Jun; 54(6):338-345. PMID: 37352399.
      Citations:    Fields:    Translation:Humans
    68. Cao JA, Patel SB, Wong CW, Garcia D, Munoz J, Cone C, Zamora D, Reagan M, Nguyen TV, Pearce W, Fish RH, Brown DM, Chaudhary V, Wykoff CC, Fan KC. Demographic and Socioeconomic Factors in Prospective Retina-Focused Clinical Trial Screening and Enrollment. J Pers Med. 2023 May 23; 13(6). PMID: 37373869; PMCID: PMC10303745.
      Citations:    
    69. Callanan D, Khurana RN, Maturi RK, Patel S, Wykoff CC, Eichenbaum D, Khanani AM, Hassan T, Badger H, Mehta S, Le G, Attar M, Seal J, Li XY. Impact of Modifying Abicipar Manufacturing Process in Patients with Neovascular Age-Related Macular Degeneration: MAPLE Study Results. Clin Ophthalmol. 2023; 17:1367-1384. PMID: 37197577; PMCID: PMC10184835.
      Citations: 1     Translation:CTClinical Trials
    70. Rao AV, Shah AR, Nguyen VT, Pearce W, Wong TP, Brown DM, Wykoff CC, Patel SB. USE OF OPTICAL COHERENCE TOMOGRAPHY IN DETECTING RETINAL TEARS IN ACUTE, SYMPTOMATIC POSTERIOR VITREOUS DETACHMENT. Retina. 2023 05 01; 43(5):802-807. PMID: 36728866.
      Citations:    Fields:    Translation:Humans
    71. Phillips MR, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Correction to: The clinician's guide to p values, confidence intervals, and magnitude of effects. Eye (Lond). 2023 May; 37(7):1515. PMID: 35046555; PMCID: PMC10170072.
      Citations:    Fields:    
    72. Karcher H, Igwe F, Freitas R, MacCumber MW, Wykoff CC, Adiguzel E, Sinha SB, Vishwakarma S, LaPrise A, Ip MS, Zarbin MA. One-Year Brolucizumab Outcomes in Neovascular Age-Related Macular Degeneration from a Large United States Cohort in the IRIS? Registry. Ophthalmology. 2023 09; 130(9):937-946. PMID: 37086857.
      Citations: 1     Fields:    Translation:Humans
    73. Nanji K, Sarohia GS, Xie J, Patil NS, Phillips M, Zeraatkar D, Thabane L, Guymer RH, Kaiser PK, Sivaprasad S, Sadda SR, Wykoff CC, Chaudhary V. Anti-vascular endothelial growth factor therapy and retinal non-perfusion in diabetic retinopathy: A meta-analysis of randomised trials. Acta Ophthalmol. 2024 Feb; 102(1):e31-e41. PMID: 37042340.
      Citations:    Fields:    
    74. Chang Y, Wang L, Phillips MR, Wykoff CC, Garg SJ, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. What makes a good survey? Eye (Lond). 2023 Nov; 37(16):3299-3301. PMID: 37029303; PMCID: PMC10630307.
      Citations:    Fields:    
    75. Parvus MN, Trejo Corona S, Fan KC, Wykoff CC. Valsalva Retinopathy After Yoga in a Patient With No Clear Predisposing Condition. J Vitreoretin Dis. 2023 Jul-Aug; 7(4):337-339. PMID: 37927323; PMCID: PMC10621705.
      Citations:    
    76. Hattenbach LO, Abreu F, Arrisi P, Basu K, Danzig CJ, Guymer R, Haskova Z, Heier JS, Kotecha A, Liu Y, Loewenstein A, Seres A, Willis JR, Wykoff CC, Paris LP. BALATON and COMINO: Phase III Randomized Clinical Trials of Faricimab for Retinal Vein Occlusion: Study Design and Rationale. Ophthalmol Sci. 2023 Sep; 3(3):100302. PMID: 37810589; PMCID: PMC10556281.
      Citations: 3     
    77. Karcher H, Igwe F, Freitas R, MacCumber MW, Wykoff CC, Adiguzel E, Sinha SB, Vishwakarma S, LaPrise A, Ip MS, Zarbin MA. Factors Linked to Injection Interval Extension in Eyes with Wet Age-Related Macular Degeneration Switched to Brolucizumab. Ophthalmology. 2023 08; 130(8):795-803. PMID: 36990322.
      Citations:    Fields:    Translation:Humans
    78. Patel SS, Lally DR, Hsu J, Wykoff CC, Eichenbaum D, Heier JS, Jaffe GJ, Westby K, Desai D, Zhu L, Khanani AM. Avacincaptad pegol for geographic atrophy secondary to age-related macular degeneration: 18-month findings from the GATHER1 trial. Eye (Lond). 2023 12; 37(17):3551-3557. PMID: 36964259; PMCID: PMC10686386.
      Citations: 2     Fields:    
    79. Kim K, Zeraatkar D, Pitre TS, Phillips M, Wykoff CC, Garg SJ, Guymer RH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Noninferiority randomised trials in ophthalmology. Eye (Lond). 2023 10; 37(15):3059-3060. PMID: 36869135; PMCID: PMC10564920.
      Citations:    Fields:    
    80. Regillo C, Berger B, Brooks L, Clark WL, Mittra R, Wykoff CC, Callaway NF, DeGraaf S, Ding HT, Fung AE, Gune S, Le Pogam S, Smith R, Willis JR, Barteselli G. Archway Phase 3 Trial of the Port Delivery System with Ranibizumab for Neovascular Age-Related Macular Degeneration 2-Year Results. Ophthalmology. 2023 Jul; 130(7):735-747. PMID: 36870451.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    81. Daruwalla C, Hsu E, Wykoff CC, Andrieni J, Uzair S, Lee AG. INTRAVITREAL ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR PHARMACEUTICAL UTILIZATION AND FINANCIAL IMPACT IN A VALUE-BASED CARE PROGRAM. Retina. 2023 03 01; 43(3):506-513. PMID: 36730588.
      Citations:    Fields:    Translation:HumansPHPublic Health
    82. Darzi AJ, Busse JW, Phillips M, Wykoff CC, Guymer RH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence and Trials INternational Alliance (R.E.T.I.N.A.) Study Group. Interpreting results from randomized controlled trials: What measures to focus on in clinical practice. Eye (Lond). 2023 Oct; 37(15):3055-3058. PMID: 36854816; PMCID: PMC10564746.
      Citations:    Fields:    
    83. Buyse M, Wang K, Gerometta M, Baldwin ME, Price CF, Jackson TL, Slakter J, Dugel PU, Wykoff CC, Boyer DS, Opthea Study Group Investigators. A Randomized Controlled Trial of OPT-302, a VEGF-C/D Inhibitor for Neovascular Age-Related Macular Degeneration. Ophthalmology. 2023 06; 130(6):588-597. PMID: 36754174.
      Citations: 5     Fields:    Translation:Humans
    84. Ding L, Kang TD, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. Combining Feature Correspondence With Parametric Chamfer Alignment: Hybrid Two-Stage Registration for Ultra-Widefield Retinal Images. IEEE Trans Biomed Eng. 2023 02; 70(2):523-532. PMID: 35925847.
      Citations:    
    85. Wang R, McClard CK, Laswell S, Mahmoudzadeh R, Salabati M, Ammar M, Vannavong J, Aziz AA, Ewald A, Calvanese AV, Lehman EB, Fried S, Windham V, Strutt A, Saroj N, Khanani AM, Eichenbaum DA, Regillo C, Wykoff CC. Quantifying burden of intravitreal injections: questionnaire assessment of life impact of treatment by intravitreal injections (QUALITII). BMJ Open Ophthalmol. 2022 12; 7(1). PMID: 36794741; PMCID: PMC9764643.
      Citations:    Fields:    Translation:Humans
    86. Chaudhary V, Sarohia GS, Phillips MR, Park D, Xie J, Zeraatkar D, Fung M, Thabane L, Loewenstein A, Holz FG, Garg SJ, Kaiser PK, Bhandari M, Guymer RH, Fraser-Bell S, Sivaprasad S, Wykoff CC. Role of anti-vascular endothelial growth factor in the management of non-proliferative diabetic retinopathy without centre-involving diabetic macular oedema: a meta-analysis of trials. Eye (Lond). 2023 07; 37(10):1966-1974. PMID: 36369263; PMCID: PMC10333362.
      Citations:    Fields:    Translation:Humans
    87. Liao DS, Grossi FV, Wykoff CC, Ribeiro RM, Rosenfeld PJ, Sadda SR. Re: Minimizing risks to patients by improving presentation of clinical trial results in geographic atrophy trials (Ophthalmol Retina. 2022;6:337-338). Ophthalmol Retina. 2022 11; 6(11):1109. PMID: 36334931.
      Citations:    Fields:    Translation:Humans
    88. Arepalli S, Wykoff CC, Abraham JR, Lunasco L, Yu H, Hu M, Srivastava SK, Reese JL, Brown D, Ehlers JP. Longitudinal analysis of aqueous humour cytokine expression and OCT-based imaging biomarkers in retinal vein occlusions treated with anti-vascular endothelial growth factor therapy in the IMAGINE study. Eye (Lond). 2023 Jun; 37(9):1928-1935. PMID: 36220884; PMCID: PMC10275974.
      Citations:    Fields:    Translation:Humans
    89. Wakatsuki Y, Hirabayashi K, Yu HJ, Marion KM, Corradetti G, Wykoff CC, Sadda SR. Optical Coherence Tomography Biomarkers for Conversion to Exudative Neovascular Age-related Macular Degeneration. Am J Ophthalmol. 2023 03; 247:137-144. PMID: 36228779.
      Citations: 1     Fields:    Translation:Humans
    90. Hirabayashi K, Yu HJ, Wakatsuki Y, Marion KM, Wykoff CC, Sadda SR. OCT Risk Factors for Development of Atrophy in Eyes with Intermediate Age-Related Macular Degeneration. Ophthalmol Retina. 2023 03; 7(3):253-260. PMID: 36208726.
      Citations: 4     Fields:    Translation:Humans
    91. Marcus DM, Silva PS, Liu D, Aiello LP, Antoszyk A, Elman M, Friedman S, Glassman AR, Googe JM, Jampol LM, Martin DF, Melia M, Preston CM, Wykoff CC, Sun JK, DRCR Retina Network. Association of Predominantly Peripheral Lesions on Ultra-Widefield Imaging and the Risk of Diabetic Retinopathy Worsening Over Time. JAMA Ophthalmol. 2022 10 01; 140(10):946-954. PMID: 35980608; PMCID: PMC9389433.
      Citations:    
    92. Silva PS, Marcus DM, Liu D, Aiello LP, Antoszyk A, Elman M, Friedman S, Glassman AR, Googe JM, Jampol LM, Martin DF, Melia M, Preston CM, Wykoff CC, Sun JK, DRCR Retina Network. Association of Ultra-Widefield Fluorescein Angiography-Identified Retinal Nonperfusion and the Risk of Diabetic Retinopathy Worsening Over Time. JAMA Ophthalmol. 2022 10 01; 140(10):936-945. PMID: 35980610; PMCID: PMC9389436.
      Citations:    
    93. Fan W, Fleming A, Hemert JV, Wykoff CC, Brown DM, Robertson G, Wang K, Falavarjani KG, Sadda SR, Ip M. RETINAL VASCULAR BED AREA IN EYES WITH RETINAL VEIN OCCLUSION ON ULTRA-WIDEFIELD FLUORESCEIN ANGIOGRAPHY: WAVE Study. Retina. 2022 10 01; 42(10):1883-1888. PMID: 35976232.
      Citations:    
    94. Parvus MN, Louis AM, Trejo Corona S, Wong TP, Major JC, Patel SB, Wykoff CC. Impact of Race and Ethnicity on Presentation and Surgical Outcomes of Idiopathic Macular Holes. J Pers Med. 2022 Sep 16; 12(9). PMID: 36143303; PMCID: PMC9506218.
      Citations:    
    95. Do DV, Moini H, Wykoff CC. Frequency and timing of antivascular endothelial growth factor treatment for eyes with centre-involved diabetic macular oedema and good vision: Protocol V results in context. BMJ Open Ophthalmol. 2022 08; 7(1). PMID: 36161828; PMCID: PMC9345046.
      Citations: 1     Fields:    Translation:Humans
    96. Lee IT, Corona ST, Wong TP, Flynn HW, Wykoff CC. Favorable Anti-VEGF Crunch Syndrome: Nonsurgical Relief of Vitreoretinal Traction in Eyes With Proliferative Diabetic Retinopathy and Tractional Retinal Detachment. Ophthalmic Surg Lasers Imaging Retina. 2022 08; 53(8):455-459. PMID: 35951712.
      Citations:    
    97. Chaudhary V, Sarohia GS, Phillips MR, Zeraatkar D, Xie JS, Nanji K, Mustafa RA, Kaiser PK, Loewenstein A, Garg SJ, Bakri SJ, Holz FG, Sivaprasad S, Bhandari M, Steel DH, Wykoff CC. Role of Positioning after Full-Thickness Macular Hole Surgery: A Systematic Review and Meta-Analysis. Ophthalmol Retina. 2023 01; 7(1):33-43. PMID: 35781067.
      Citations:    Fields:    
    98. Wykoff CC, Campochiaro PA, Pieramici DJ, Khanani AM, Gune S, Maia M, Ding HT, Maass KF, K?gedal M. Pharmacokinetics of the Port Delivery System with Ranibizumab in the Ladder Phase 2 Trial for Neovascular Age-Related Macular Degeneration. Ophthalmol Ther. 2022 Oct; 11(5):1705-1717. PMID: 35759124; PMCID: PMC9437184.
      Citations:    
    99. Boone CV, Wykoff CC, Fine HF. From Bench to Bedside: Faricimab Enters the Clinic. Ophthalmic Surg Lasers Imaging Retina. 2022 Jun; 53(6):305-309. PMID: 35724370.
      Citations:    Fields:    
    100. Parpia S, Morris TP, Phillips MR, Wykoff CC, Steel DH, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Sensitivity analysis in clinical trials: three criteria for a valid sensitivity analysis. Eye (Lond). 2022 11; 36(11):2073-2074. PMID: 35585134; PMCID: PMC9581998.
      Citations:    Fields:    
    101. Nichani PAH, Dhoot AS, Popovic MM, Eshtiaghi A, Mihalache A, Sayal AP, Yu HJ, Wykoff CC, Kertes PJ, Muni RH. Scleral Buckling Alone or in Combination with Pars Plana Vitrectomy for Rhegmatogenous Retinal Detachment Repair: A Meta-Analysis of 7,212 Eyes. Ophthalmologica. 2022; 245(4):296-314. PMID: 35533652.
      Citations:    Fields:    
    102. Khanani AM, Brown DM, Jaffe GJ, Wykoff CC, Adiguzel E, Wong R, Meng X, Heier JS, MERLIN Investigators. MERLIN: Phase 3a, Multicenter, Randomized, Double-Masked Trial of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid. Ophthalmology. 2022 09; 129(9):974-985. PMID: 35537533.
      Citations:    Fields:    
    103. Khanani AM, Graff JM, Marcus DM, Wykoff CC, Jhaveri CD, Barteselli G, Malhotra VK, Menezes AR, Callaway NF. Refill-Exchange Procedure of the Port Delivery System With Ranibizumab: Overview and Clinical Trial Experience. Ophthalmic Surg Lasers Imaging Retina. 2022 05; 53(5):257-265. PMID: 35575741.
      Citations:    Fields:    Translation:Humans
    104. Sarohia GS, Nanji K, Khan M, Khalid MF, Rosenberg D, Deonarain DM, Phillips MR, Thabane L, Kaiser PK, Garg SJ, Sivaprasad S, Wykoff CC, Chaudhary V. Treat-and-extend versus alternate dosing strategies with anti-vascular endothelial growth factor agents to treat center involving diabetic macular edema: A systematic review and meta-analysis of 2,346 eyes. Surv Ophthalmol. 2022 Sep-Oct; 67(5):1346-1363. PMID: 35476929.
      Citations:    Fields:    
    105. Rosenberg D, Deonarain DM, Gould J, Sothivannan A, Phillips MR, Sarohia GS, Sivaprasad S, Wykoff CC, Cheung CMG, Sarraf D, Bakri SJ, Chaudhary V. Efficacy, safety, and treatment burden of treat-and-extend versus alternative anti-VEGF regimens for nAMD: a systematic review and meta-analysis. Eye (Lond). 2023 01; 37(1):6-16. PMID: 35396574; PMCID: PMC9829919.
      Citations:    Fields:    
    106. Sirks MJ, van Dijk EHC, Rosenberg N, Hollak CEM, Aslanis S, Cheung CMG, Chowers I, Eandi CM, Freund KB, Holz FG, Kaiser PK, Lotery AJ, Ohno-Matsui K, Querques G, Subhi Y, Tadayoni R, Wykoff CC, Zur D, Diederen RMH, Boon CJF, Schlingemann RO. Clinical impact of the worldwide shortage of verteporfin (Visudyne?) on ophthalmic care. Acta Ophthalmol. 2022 Nov; 100(7):e1522-e1532. PMID: 35388619; PMCID: PMC9790583.
      Citations: 1     Fields:    
    107. Fan W, Uji A, Wykoff CC, Brown DM, van Hemert J, Falavarjani KG, Wang K, Sadda SR, Ip M. Baseline retinal vascular bed area on ultra-wide field fluorescein angiography correlates with the anatomical outcome of diabetic macular oedema to ranibizumab therapy: two-year analysis of the DAVE Study. Eye (Lond). 2023 03; 37(4):678-683. PMID: 35332289; PMCID: PMC9998428.
      Citations:    Fields:    
    108. Wykoff CC, Nittala MG, Villanueva Boone C, Yu HJ, Fan W, Velaga SB, Ehlers JP, Ip MS, Sadda SR, RECOVERY Study Group. Final Outcomes from the Randomized RECOVERY Trial of Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2022 07; 6(7):557-566. PMID: 35257962.
      Citations:    Fields:    Translation:Humans
    109. Dugel PU, Jhaveri CD, Chakravarthy U, Wykoff CC, Singh RP, Hamilton R, Weissgerber G, Mulyukov Z, Holz FG. EFFECT OF RETINAL THICKNESS VARIABILITY ON VISUAL OUTCOMES AND FLUID PERSISTENCE IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION: A Post Hoc Analysis of the HAWK and HARRIER Studies. Retina. 2022 03 01; 42(3):511-518. PMID: 34923515.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    110. Fan W, Nittala MG, Wykoff CC, Brown DM, Uji A, Hemert JV, Fleming A, Robertson G, Sadda SR, Ip M. NEW BIOMARKER QUANTIFYING THE EFFECT OF ANTI-VEGF THERAPY IN EYES WITH PROLIFERATIVE DIABETIC RETINOPATHY ON ULTRAWIDE FIELD FLUORESCEIN ANGIOGRAPHY: RECOVERY Study. Retina. 2022 03 01; 42(3):426-433. PMID: 34803132.
      Citations:    Fields:    Translation:Humans
    111. Eshtiaghi A, Dhoot AS, Mihalache A, Popovic MM, Nichani PAH, Sayal AP, Yu HJ, Wykoff CC, Kertes PJ, Muni RH. Pars Plana Vitrectomy with and without Supplemental Scleral Buckle for the Repair of Rhegmatogenous Retinal Detachment: A Meta-analysis. Ophthalmol Retina. 2022 10; 6(10):871-885. PMID: 35227949.
      Citations: 1     Fields:    
    112. Qasim A, Devji T, Phillips MR, Wykoff CC, Kaiser PK, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. Seeing the patient's perspective: a guide to patient-reported outcome measures and minimal important differences in ophthalmic research. Eye (Lond). 2022 07; 36(7):1339-1341. PMID: 35197561; PMCID: PMC9232633.
      Citations:    Fields:    Translation:Humans
    113. Phillips MR, Steel DH, Wykoff CC, Busse JW, Bannuru RR, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. A clinician's guide to network meta-analysis. Eye (Lond). 2022 08; 36(8):1523-1526. PMID: 35145277; PMCID: PMC9307840.
      Citations:    Fields:    Translation:Humans
    114. Kar SS, Abraham J, Wykoff CC, Sevgi DD, Lunasco L, Brown DM, Srivastava SK, Madabhushi A, Ehlers JP. Computational Imaging Biomarker Correlation with Intraocular Cytokine Expression in Diabetic Macular Edema: Radiomics Insights from the IMAGINE Study. Ophthalmol Sci. 2022 Jun; 2(2):100123. PMID: 36249694; PMCID: PMC9560558.
      Citations:    
    115. Bzovsky S, Phillips MR, Guymer RH, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, R.E.T.I.N.A. study group. The clinician's guide to interpreting a regression analysis. Eye (Lond). 2022 09; 36(9):1715-1717. PMID: 35102247; PMCID: PMC9391441.
      Citations:    Fields:    
    116. Wykoff CC, Abreu F, Adamis AP, Basu K, Eichenbaum DA, Haskova Z, Lin H, Loewenstein A, Mohan S, Pearce IA, Sakamoto T, Silverman D, Sun JK, Wells JA, Willis JR, YOSEMITE and RHINE Investigators, Schlottmann PG, Tadayoni R. Efficacy, durability, and safety of intravitreal faricimab with extended dosing up to every 16 weeks in patients with diabetic macular oedema (YOSEMITE and RHINE): two randomised, double-masked, phase 3 trials. Lancet. 2022 02 19; 399(10326):741-755. PMID: 35085503.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    117. Stenz EC, Yu HJ, Shah AR, Wong TP, Major JC, Benz MS, Wykoff CC, Patel SB. Outcomes of Eyes Undergoing Multiple Surgical Interventions after Failure of Primary Rhegmatogenous Retinal Detachment Repair. Ophthalmol Retina. 2022 05; 6(5):339-346. PMID: 35074559.
      Citations:    Fields:    Translation:Humans
    118. Wykoff CC, Yu HJ, Avery RL, Ehlers JP, Sadda SR, Tadayoni R. Retinal non-perfusion in diabetic retinopathy. Eye (Lond). 2022 02; 36(2):249-256. PMID: 35017700; PMCID: PMC8807828.
      Citations:    Fields:    Translation:Humans
    119. Khanani AM, Zarbin MA, Barakat MR, Albini TA, Kaiser PK, B G, Agashivala N, Yu JS, Wykoff CC, MacCumber MW. Safety Outcomes of Brolucizumab in Neovascular Age-Related Macular Degeneration: Results From the IRIS Registry and Komodo Healthcare Map. JAMA Ophthalmol. 2022 Jan 01; 140(1):20-28. PMID: 34817566; PMCID: PMC8613703.
      Citations: 3     Fields:    Translation:Humans
    120. Eter N, Singh RP, Abreu F, Asik K, Basu K, Baumal C, Chang A, Csaky KG, Haskova Z, Lin H, Ruiz CQ, Ruamviboonsuk P, Silverman D, Wykoff CC, Willis JR. YOSEMITE and RHINE: Phase 3 Randomized Clinical Trials of Faricimab for Diabetic Macular Edema: Study Design and Rationale. Ophthalmol Sci. 2022 Mar; 2(1):100111. PMID: 36246184; PMCID: PMC9559760.
      Citations: 6     
    121. Singh RP, Jhaveri C, Wykoff CC, Gale RP, Staurenghi G, Iida T, Koh A, B G, Gedif K, Singer M. Efficacy Outcomes of Brolucizumab Versus Aflibercept in Neovascular Age-Related Macular Degeneration Patients with Early Residual Fluid. Ophthalmol Retina. 2022 05; 6(5):377-386. PMID: 34968756.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    122. Chao DL, Rinella NT, Khanani AM, Wykoff CC, Kim GH. Cooling Anesthesia for Intravitreal Injection: Results of the Prospective Open-Label, Dose-Ranging COOL-1 Trial. Clin Ophthalmol. 2021; 15:4659-4666. PMID: 34916777; PMCID: PMC8670887.
      Citations:    Translation:CTClinical Trials
    123. Dhoot AS, Popovic MM, Nichani PAH, Eshtiaghi A, Mihalache A, Sayal AP, Yu H, Wykoff CC, Kertes PJ, Muni RH. Pars plana vitrectomy versus scleral buckle: A comprehensive meta-analysis of 15,947 eyes. Surv Ophthalmol. 2022 Jul-Aug; 67(4):932-949. PMID: 34896191.
      Citations: 2     Fields:    Translation:Humans
    124. Nanji K, Sarohia GS, Kennedy K, Ceyhan T, McKechnie T, Phillips M, Devji T, Thabane L, Kaiser P, Sarraf D, Garg SJ, Sivaprasad S, Wykoff CC, Bakri SJ, Sheidow T, Bhandari M, Chaudhary V. The 12- and 24-Month Effects of Intravitreal Ranibizumab, Aflibercept, and Bevacizumab on Intraocular Pressure: A Network Meta-Analysis. Ophthalmology. 2022 05; 129(5):498-508. PMID: 34871637.
      Citations:    Fields:    Translation:Humans
    125. Yu JS, Sagkriotis A, B G, Agashivala N, MacCumber MW, Burugapalli B, Bi X, Wykoff CC. Antivascular endothelial growth factor agents for wet age-related macular degeneration: an IRIS registry analysis. Can J Ophthalmol. 2023 06; 58(3):252-261. PMID: 34863677.
      Citations:    Fields:    
    126. Nanji K, Khan M, Khalid MF, Xie JS, Sarohia GS, Phillips M, Thabane L, Garg SJ, Kaiser P, Sivaprasad S, Wykoff CC, Chaudhary V. Treat-and-extend regimens of anti-vascular endothelial growth factor therapy for retinal vein occlusions: a systematic review and meta-analysis. Acta Ophthalmol. 2022 Sep; 100(6):e1199-e1208. PMID: 34845830.
      Citations:    Fields:    
    127. Phillips MR, Wykoff CC, Thabane L, Bhandari M, Chaudhary V, Retina Evidence Trials InterNational Alliance (R.E.T.I.N.A.) Study Group. The clinician's guide to p values, confidence intervals, and magnitude of effects. Eye (Lond). 2022 02; 36(2):341-342. PMID: 34837035; PMCID: PMC8807597.
      Citations:    Fields:    Translation:Humans
    128. Rosenberg DM, Ghayur HS, Deonarain DM, Sarohia GS, Phillips MR, Garg S, Bakri SJ, Wykoff CC, Chaudhary V. Supplemental Scleral Buckle for the Management of Rhegmatogenous Retinal Detachment by Pars Plana Vitrectomy: A Meta-Analysis of Randomized Controlled Trials. Ophthalmologica. 2022; 245(2):101-110. PMID: 34731858.
      Citations:    Fields:    Translation:Humans
    129. Babiuch AS, Wykoff CC, Yordi S, Yu H, Srivastava SK, Hu M, Le TK, Lunasco L, Reese J, Nittala MG, Sadda SR, Ehlers JP. The 2-Year Leakage Index and Quantitative Microaneurysm Results of the RECOVERY Study: Quantitative Ultra-Widefield Findings in Proliferative Diabetic Retinopathy Treated with Intravitreal Aflibercept. J Pers Med. 2021 Nov 01; 11(11). PMID: 34834478; PMCID: PMC8619795.
      Citations: 1     
    130. Jhaveri C, Wykoff CC, Khanani AM, Eandi CM, Chang A, B G, Gedif KA, Singer M. Early Residual Fluid-Free Status and Long-Term BCVA Outcomes: A Treatment Agnostic, Post Hoc Analysis of Pooled HAWK and HARRIER Data. Am J Ophthalmol. 2022 04; 236:12-19. PMID: 34695400.
      Citations:    Fields:    Translation:Humans
    131. Ding L, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. Weakly-Supervised Vessel Detection in Ultra-Widefield Fundus Photography via Iterative Multi-Modal Registration and Learning. IEEE Trans Med Imaging. 2021 10; 40(10):2748-2758. PMID: 32991281; PMCID: PMC8513803.
      Citations: 6     Fields:    Translation:Humans
    132. Fang M, Chanwimol K, Maram J, Datoo O'Keefe GA, Wykoff CC, Sarraf D, Brown A, Lampen SIR, Zhou B, Rusakevich AM, Sadda S. Morphological characteristics of eyes with neovascular age-related macular degeneration and good long-term visual outcomes after anti-VEGF therapy. Br J Ophthalmol. 2023 03; 107(3):399-405. PMID: 34561217.
      Citations:    Fields:    
    133. Wykoff CC, Hershberger V, Eichenbaum D, Henry E, Younis HS, Chandra P, Yuan N, Solloway M, DePaoli A. Inhibition of Complement Factor 3 in Geographic Atrophy with NGM621: Phase 1 Dose-Escalation Study Results. Am J Ophthalmol. 2022 03; 235:131-142. PMID: 34509438.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    134. Yu HJ, Ehlers JP, Sevgi DD, O'Connell M, Reese JL, Srivastava SK, Wykoff CC. Real-Time Diabetic Retinopathy Severity Score Level versus Ultra-Widefield Leakage Index-Guided Management of Diabetic Retinopathy: Two-Year Outcomes from the Randomized PRIME Trial. J Pers Med. 2021 Sep 04; 11(9). PMID: 34575662; PMCID: PMC8465170.
      Citations: 1     
    135. Heier JS, Singh RP, Wykoff CC, Csaky KG, Lai TYY, Loewenstein A, Schlottmann PG, Paris LP, Westenskow PD, Quezada-Ruiz C. Reply. Retina. 2021 09 01; 41(9):e56-e58. PMID: 34432748.
      Citations:    Fields:    
    136. Brown DM, Wykoff CC, Boyer D, Heier JS, Clark WL, Emanuelli A, Higgins PM, Singer M, Weinreich DM, Yancopoulos GD, Berliner AJ, Chu K, Reed K, Cheng Y, Vitti R. Evaluation of Intravitreal Aflibercept for the Treatment of Severe Nonproliferative Diabetic Retinopathy: Results From the PANORAMA Randomized Clinical Trial. JAMA Ophthalmol. 2021 Sep 01; 139(9):946-955. PMID: 34351414; PMCID: PMC8343518.
      Citations: 7     Fields:    Translation:Humans
    137. Sevgi DD, Srivastava SK, Wykoff C, Scott AW, Hach J, O'Connell M, Whitney J, Vasanji A, Reese JL, Ehlers JP. Deep learning-enabled ultra-widefield retinal vessel segmentation with an automated quality-optimized angiographic phase selection tool. Eye (Lond). 2022 09; 36(9):1783-1788. PMID: 34373610; PMCID: PMC9391395.
      Citations:    Fields:    
    138. Kaiser PK, Wykoff CC, Singh RP, Khanani AM, Do DV, Patel H, Patel N. RETINAL FLUID AND THICKNESS AS MEASURES OF DISEASE ACTIVITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION. Retina. 2021 Aug 01; 41(8):1579-1586. PMID: 33949342; PMCID: PMC8297539.
      Citations: 3     Fields:    Translation:Humans
    139. Jain N, Liao A, Garg SJ, Patel SN, Wykoff CC, Yu HJ, London NJS, Khurana RN, Zacks DN, Macula Society Pentosan Polysulfate Maculopathy Study Group. Expanded Clinical Spectrum of Pentosan Polysulfate Maculopathy: A Macula Society Collaborative Study. Ophthalmol Retina. 2022 03; 6(3):219-227. PMID: 34298229.
      Citations: 1     Fields:    Translation:Humans
    140. Abraham JR, Wykoff CC, Arepalli S, Lunasco L, Yu HJ, Martin A, Mugnaini C, Hu M, Reese J, Srivastava SK, Brown DM, Ehlers JP. Exploring the angiographic-biologic phenotype in the IMAGINE study: quantitative UWFA and cytokine expression. Br J Ophthalmol. 2022 10; 106(10):1444-1449. PMID: 34099465; PMCID: PMC8761372.
      Citations: 2     Fields:    
    141. Yu JS, Carlton R, Agashivala N, Hassan T, Wykoff CC. Brolucizumab vs aflibercept and ranibizumab for neovascular age-related macular degeneration: a cost-effectiveness analysis. J Manag Care Spec Pharm. 2021 Jun; 27(6):743-752. PMID: 34057392; PMCID: PMC10390922.
      Citations: 3     Fields:    Translation:Humans
    142. Heier JS, Brown DM, Shah SP, Saroj N, Dang S, Waheed NK, Wykoff CC, Prenner JL, Boyer DS. Intravitreal Aflibercept Injection vs Sham as Prophylaxis Against Conversion to Exudative Age-Related Macular Degeneration in High-risk Eyes: A Randomized Clinical Trial. JAMA Ophthalmol. 2021 May 01; 139(5):542-547. PMID: 33734306; PMCID: PMC7974836.
      Citations: 1     Fields:    Translation:Humans
    143. Yu HJ, Wykoff CC. Investigational Agents in Development for the Treatment of Geographic Atrophy Secondary to Age-Related Macular Degeneration. BioDrugs. 2021 May; 35(3):303-323. PMID: 33893984.
      Citations: 1     Fields:    Translation:Humans
    144. McClard CK, Wang R, Windham V, Munoz J, Gomez S, Fried S, Saroj N, Regillo C, Wykoff CC, Strutt AM. Questionnaire to Assess Life Impact of Treatment by Intravitreal Injections (QUALITII): Development of a patient-reported measure to assess treatment burden of repeat intravitreal injections. BMJ Open Ophthalmol. 2021; 6(1):e000669. PMID: 33912685; PMCID: PMC8031709.
      Citations: 3     
    145. Fan W, Uji A, Nittala M, Wykoff CC, Brown D, Fleming A, Robertson G, van Hemert J, Sadda S, Ip MS. Retinal vascular bed area on ultra-wide field fluorescein angiography indicates the severity of diabetic retinopathy. Br J Ophthalmol. 2022 08; 106(8):1126-1131. PMID: 33827861.
      Citations: 3     Fields:    Translation:Humans
    146. Breazzano MP, Nair AA, Arevalo JF, Barakat MR, Berrocal AM, Chang JS, Chen A, Eliott D, Garg SJ, Ghadiali Q, Gong D, Grewal DS, Handa JT, Henderson M, Leiderman YI, Leng T, Mannina A, Mendel TA, Mustafi D, de Koo LCO, Patel SN, Patel TP, Prenner J, Richards P, Singh RP, Wykoff CC, Yannuzzi NA, Yu H, Modi YS, Chang S. Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic. JAMA Ophthalmol. 2021 04 01; 139(4):456-463. PMID: 33662093; PMCID: PMC7934075.
      Citations: 13     Fields:    Translation:HumansCells
    147. Wykoff CC, Rosenfeld PJ, Waheed NK, Singh RP, Ronca N, Slakter JS, Staurenghi G, Baumal CR, Saroj N, Metlapally R, Ribeiro R, Mon?s J. Characterizing New-Onset Exudation in the Randomized Phase 2 FILLY Trial of Complement Inhibitor Pegcetacoplan for Geographic Atrophy. Ophthalmology. 2021 09; 128(9):1325-1336. PMID: 33711380.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    148. Yu HJ, Ehlers JP, Sevgi DD, Hach J, O'Connell M, Reese JL, Srivastava SK, Wykoff CC. Real-Time Photographic- and Fluorescein Angiographic-Guided Management of Diabetic Retinopathy: Randomized PRIME Trial Outcomes. Am J Ophthalmol. 2021 06; 226:126-136. PMID: 33529593.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    149. Wykoff CC, Khurana RN, Nguyen QD, Kelly SP, Lum F, Hall R, Abbass IM, Abolian AM, Stoilov I, To TM, Garmo V. Risk of Blindness Among Patients With Diabetes and Newly Diagnosed Diabetic Retinopathy. Diabetes Care. 2021 03; 44(3):748-756. PMID: 33472864; PMCID: PMC7896265.
      Citations: 7     Fields:    Translation:Humans
    150. Yu HJ, Kiernan DF, Eichenbaum D, Sheth VS, Wykoff CC. Reply. Ophthalmol Retina. 2021 01; 5(1):e1-e2. PMID: 33413801.
      Citations:    Fields:    Translation:Humans
    151. Heier JS, Singh RP, Wykoff CC, Csaky KG, Lai TYY, Loewenstein A, Schlottmann PG, Paris LP, Westenskow PD, Quezada-Ruiz C. THE ANGIOPOIETIN/TIE PATHWAY IN RETINAL VASCULAR DISEASES: A Review. Retina. 2021 01 01; 41(1):1-19. PMID: 33136975.
      Citations: 4     Fields:    Translation:HumansCells
    152. Khurana RN, Kunimoto D, Yoon YH, Wykoff CC, Chang A, Maturi RK, Souied E, Chow DR, Lotery AJ, Ohji M, Bandello F, Li XY, Jiao J, Le G, Kim K, Schmidt W, Hashad Y, CEDAR and SEQUOIA Study Groups, Agostini H, Belfort R. Two-Year Results of the Phase 3 Randomized Controlled Study of Abicipar in Neovascular Age-Related Macular Degeneration. Ophthalmology. 2021 07; 128(7):1027-1038. PMID: 33221326.
      Citations: 7     Fields:    Translation:Humans
    153. Singer MA, Wykoff CC, Grewal DS. Effects of Long-Term DME Control With 0.2 ?g/Day Fluocinolone Acetonide Implant on Quality of Life: An Exploratory Analysis From the FAME Trial. Ophthalmic Surg Lasers Imaging Retina. 2020 11 01; 51(11):658-667. PMID: 33231701.
      Citations:    Fields:    Translation:Humans
    154. Babiuch AS, Wykoff CC, Srivastava SK, Talcott K, Zhou B, Hach J, Hu M, Reese JL, Ehlers JP. RETINAL LEAKAGE INDEX DYNAMICS ON ULTRA-WIDEFIELD FLUORESCEIN ANGIOGRAPHY IN EYES TREATED WITH INTRAVITREAL AFLIBERCEPT FOR PROLIFERATIVE DIABETIC RETINOPATHY IN THE RECOVERY STUDY. Retina. 2020 Nov; 40(11):2175-2183. PMID: 31917731.
      Citations: 3     Fields:    Translation:Humans
    155. Wan CR, Kapik B, Wykoff CC, Henry CR, Barakat MR, Shah M, Andino RV, Ciulla TA. Clinical Characterization of Suprachoroidal Injection Procedure Utilizing a Microinjector across Three Retinal Disorders. Transl Vis Sci Technol. 2020 10; 9(11):27. PMID: 33150052; PMCID: PMC7585395.
      Citations: 1     Fields:    Translation:Humans
    156. Bawany MH, Ding L, Ramchandran RS, Sharma G, Wykoff CC, Kuriyan AE. Automated vessel density detection in fluorescein angiography images correlates with vision in proliferative diabetic retinopathy. PLoS One. 2020; 15(9):e0238958. PMID: 32915904; PMCID: PMC7485882.
      Citations: 3     Fields:    Translation:Humans
    157. Abraham JR, Wykoff CC, Arepalli S, Lunasco L, Yu HJ, Hu M, Reese J, Srivastava SK, Brown DM, Ehlers JP. Aqueous Cytokine Expression and Higher Order OCT Biomarkers: Assessment of the Anatomic-Biologic Bridge in the IMAGINE DME Study. Am J Ophthalmol. 2021 02; 222:328-339. PMID: 32896498; PMCID: PMC9719825.
      Citations: 6     Fields:    Translation:Humans
    158. Alagorie AR, Velaga S, Nittala MG, Yu HJ, Wykoff CC, Sadda SR. Effect of Aflibercept on Diabetic Retinopathy Severity and Visual Function in the RECOVERY Study for Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2021 05; 5(5):409-419. PMID: 32882447.
      Citations: 1     Fields:    Translation:Humans
    159. Gupta MP, Sridhar J, Wykoff CC, Yonekawa Y. Ophthalmology conferences in the coronavirus disease 2019 era. Curr Opin Ophthalmol. 2020 Sep; 31(5):396-402. PMID: 32740066.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    160. Chen A, Dang S, Chung MM, Ramchandran RS, Bessette AP, DiLoreto DA, Kleinman DM, Sridhar J, Wykoff CC, Kuriyan AE. Quantitative Comparison of Fundus Images by 2 Ultra-Widefield Fundus Cameras. Ophthalmol Retina. 2021 05; 5(5):450-457. PMID: 32866664; PMCID: PMC8501635.
      Citations: 3     Fields:    Translation:Humans
    161. Babiuch A, Wykoff CC, Hach J, Srivastava S, Talcott KE, Yu HJ, Nittala M, Sadda S, Ip MS, Le T, Hu M, Reese J, Ehlers JP. Longitudinal panretinal microaneurysm dynamics on ultra-widefield fluorescein angiography in eyes treated with intravitreal aflibercept for proliferative diabetic retinopathy in the recovery study. Br J Ophthalmol. 2021 08; 105(8):1111-1115. PMID: 32829304.
      Citations: 5     Fields:    Translation:Humans
    162. Barakat MR, Wykoff CC, Gonzalez V, Hu A, Marcus D, Zavaleta E, Ciulla TA. Suprachoroidal CLS-TA plus Intravitreal Aflibercept for Diabetic Macular Edema: A Randomized, Double-Masked, Parallel-Design, Controlled Study. Ophthalmol Retina. 2021 01; 5(1):60-70. PMID: 32829027.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    163. Yu HJ, Kiernan DF, Eichenbaum D, Sheth VS, Wykoff CC. Home Monitoring of Age-Related Macular Degeneration: Utility of the ForeseeHome Device for Detection of Neovascularization. Ophthalmol Retina. 2021 04; 5(4):348-356. PMID: 32810682; PMCID: PMC7428765.
      Citations: 3     Fields:    Translation:Humans
    164. Alagorie AR, Nittala MG, Velaga S, Zhou B, Rusakevich AM, Wykoff CC, Sadda SR. Association of Intravitreal Aflibercept With Optical Coherence Tomography Angiography Vessel Density in Patients With Proliferative Diabetic Retinopathy: A Secondary Analysis of a Randomized Clinical Trial. JAMA Ophthalmol. 2020 08 01; 138(8):851-857. PMID: 32584384; PMCID: PMC7317653.
      Citations: 9     Fields:    Translation:Humans
    165. Chao DL, Sridhar J, Kuriyan AE, Leng T, Barnett BP, Carlin AF, Wykoff CC, Gayer S, Mruthyunjaya P, Yonekawa Y, Fawzi AA, Berrocal AM, Yeh S, Ting D, Modi Y, Zacks DN, Yannuzzi N, Afshari NA, Murray T. Rationale for American Society of Retina Specialists Best Practice Recommendations for Conducting Vitreoretinal Surgery during the COVID-19 Era. J Vitreoretin Dis. 2020 Oct 01; 4(5):420-429. PMID: 34222758; PMCID: PMC8247449.
      Citations:    
    166. Hussain RM, Weng CY, Wykoff CC, Gandhi RA, Hariprasad SM. Abicipar pegol for neovascular age-related macular degeneration. Expert Opin Biol Ther. 2020 09; 20(9):999-1008. PMID: 32552072.
      Citations: 4     Fields:    Translation:HumansCells
    167. Fan W, Uji A, Wang K, Falavarjani KG, Wykoff CC, Brown DM, Van Hemert J, Sagong M, Sadda SR, Ip M. SEVERITY OF DIABETIC MACULAR EDEMA CORRELATES WITH RETINAL VASCULAR BED AREA ON ULTRA-WIDE FIELD FLUORESCEIN ANGIOGRAPHY: DAVE Study. Retina. 2020 Jun; 40(6):1029-1037. PMID: 31356494.
      Citations: 8     Fields:    Translation:Humans
    168. Puliafito CA, Wykoff CC. New Frontiers in Retina: highlights of the 2020 angiogenesis, exudation and degeneration symposium. Int J Retina Vitreous. 2020; 6:18. PMID: 32477592; PMCID: PMC7243329.
      Citations: 6     
    169. Ding L, Bawany MH, Kuriyan AE, Ramchandran RS, Wykoff CC, Sharma G. A Novel Deep Learning Pipeline for Retinal Vessel Detection In Fluorescein Angiography. IEEE Trans Image Process. 2020 May 08. PMID: 32396087; PMCID: PMC7648732.
      Citations: 4     Fields:    
    170. Yu HJ, Kaiser PK, Zamora D, Bocanegra M, Cone C, Brown DM, Sadda SR, Wykoff CC. Visual Acuity Variability: Comparing Discrepancies between Snellen and ETDRS Measurements among Subjects Entering Prospective Trials. Ophthalmol Retina. 2021 03; 5(3):224-233. PMID: 32595096.
      Citations: 2     Fields:    Translation:Humans
    171. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Long-term outcomes of treat-and-extend ranibizumab with and without navigated laser for diabetic macular oedema: TREX-DME 3-year results. Br J Ophthalmol. 2021 02; 105(2):253-257. PMID: 32303499.
      Citations:    Fields:    Translation:Humans
    172. Kunimoto D, Yoon YH, Wykoff CC, Chang A, Khurana RN, Maturi RK, Souied E, Chow DR, Lotery AJ, Ohji M, Bandello F, Li XY, Jiao J, Le G, Schmidt W, Hashad Y, CEDAR and SEQUOIA Study Groups, Agostini H, Belfort R. Efficacy and Safety of Abicipar in Neovascular Age-Related Macular Degeneration: 52-Week Results of Phase 3 Randomized Controlled Study. Ophthalmology. 2020 10; 127(10):1331-1344. PMID: 32471729.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    173. Glassman AR, Baker CW, Beaulieu WT, Bressler NM, Punjabi OS, Stockdale CR, Wykoff CC, Jampol LM, Sun JK, DRCR Retina Network. Assessment of the DRCR Retina Network Approach to Management With Initial Observation for Eyes With Center-Involved Diabetic Macular Edema and Good Visual Acuity: A Secondary Analysis of a Randomized Clinical Trial. JAMA Ophthalmol. 2020 04 01; 138(4):341-349. PMID: 32077907; PMCID: PMC7042938.
      Citations: 11     Fields:    Translation:Humans
    174. Suresh R, Yu HJ, Thoveson A, Swisher J, Apolinario M, Zhou B, Shah AR, Fish RH, Wykoff CC. Loss to Follow-Up Among Patients With Proliferative Diabetic Retinopathy in Clinical Practice. Am J Ophthalmol. 2020 07; 215:66-71. PMID: 32209344.
      Citations: 2     Fields:    Translation:Humans
    175. Major JC, Lampen SIR, Wykoff CC, Ou WC, Brown DM, Wong TP, Shah AR. THE TEXAS TACO TECHNIQUE FOR INTERNAL LIMITING MEMBRANE FLAP IN LARGE FULL-THICKNESS MACULAR HOLES: A Short-Term Pilot Study. Retina. 2020 Mar; 40(3):552-556. PMID: 30608347.
      Citations: 1     Fields:    Translation:Humans
    176. Campbell J, Almony A, Shih V, Serbin M, LaPrise A, Wykoff CC, Kiss S. Management and Outcomes for Neovascular Age-Related Macular Degeneration: Analysis of United States Electronic Health Records. Ophthalmology. 2020 09; 127(9):1179-1188. PMID: 32345477.
      Citations: 4     Fields:    Translation:Humans
    177. Yonekawa Y, Modi YS, Kim LA, Skondra D, Kim JE, Wykoff CC. American Society of Retina Specialists Clinical Practice Guidelines on the Management of Nonproliferative and Proliferative Diabetic Retinopathy without Diabetic Macular Edema. J Vitreoretin Dis. 2020 Mar 01; 4(2):125-135. PMID: 34308094; PMCID: PMC8297841.
      Citations:    
    178. Holekamp N, Wykoff CC, Schmitz-Valckenberg S, Lin H, Rabena MD, Cantrell RA, Henry EC, Tang F, Swaminathan B, Martin J, Ferrara D, Staurenghi G, Mon?s J, Souied EH. Natural History of Geographic Atrophy Secondary to Age-Related Macular Degeneration: Results from the Prospective Proxima A and B Clinical Trials. Ophthalmology. 2020 06; 127(6):769-783. PMID: 32081489.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    179. Zhou B, Mitchell TC, Rusakevich AM, Brown DM, Wykoff CC. Noncompliance in Prospective Retina Clinical Trials: Analysis of Factors Predicting Loss to Follow-up. Am J Ophthalmol. 2020 02; 210:86-96. PMID: 31647931.
      Citations: 3     Fields:    Translation:Humans
    180. Hinkle JW, Wykoff CC, Lim JI, Hahn P, Kim SJ, Tabandeh H, Flynn HW. "Iodine Allergy" and the Use of Povidone Iodine for Endophthalmitis Prophylaxis. J Vitreoretin Dis. 2020 Jan-Feb; 4(1):65-68. PMID: 37009565; PMCID: PMC9976080.
      Citations:    
    181. Singh RP, Hsueh J, Han MM, Kuriyan AE, Conti FF, Steinle N, Weng CY, Wong RW, Martinez JA, Wykoff CC. Protecting Vision in Patients With Diabetes With Ultra-Widefield Imaging: A Review of Current Literature. Ophthalmic Surg Lasers Imaging Retina. 2019 10 01; 50(10):639-648. PMID: 31671197.
      Citations: 1     Fields:    Translation:Humans
    182. Heier JS, Wykoff CC, Waheed NK, Kitchens JW, Patel SS, Vitti R, Perlee L, Chu KW, Leal S, Asmus F, Son V, Schmelter T, Brown DM. Intravitreal Combined Aflibercept?+ Anti-Platelet-Derived Growth Factor Receptor ? for Neovascular Age-Related Macular Degeneration: Results of the Phase 2 CAPELLA Trial. Ophthalmology. 2020 02; 127(2):211-220. PMID: 31791663.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    183. Rusakevich AM, Zhou B, Wong TP, Wykoff CC. Quarterly Anti-Vascular Endothelial Growth Factor Dosing for Neovascular Age-Related Macular Degeneration: Real-World Clinical Outcomes. Ophthalmic Surg Lasers Imaging Retina. 2019 09 01; 50(9):e250-e256. PMID: 31589766.
      Citations: 1     Fields:    Translation:Humans
    184. Fan W, Nittala MG, Fleming A, Robertson G, Uji A, Wykoff CC, Brown DM, van Hemert J, Ip M, Wang K, Falavarjani KG, Singer M, Sagong M, Sadda SR. Relationship Between Retinal Fractal Dimension and Nonperfusion in Diabetic Retinopathy on Ultrawide-Field Fluorescein Angiography. Am J Ophthalmol. 2020 01; 209:99-106. PMID: 31472160.
      Citations: 9     Fields:    Translation:Humans
    185. Wykoff CC, Nittala MG, Zhou B, Fan W, Velaga SB, Lampen SIR, Rusakevich AM, Ehlers JP, Babiuch A, Brown DM, Ip MS, Sadda SR, Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy Study Group. Intravitreal Aflibercept for Retinal Nonperfusion in Proliferative Diabetic Retinopathy: Outcomes from the Randomized RECOVERY Trial. Ophthalmol Retina. 2019 12; 3(12):1076-1086. PMID: 31542339.
      Citations: 17     Fields:    Translation:Humans
    186. Wykoff CC. Thresholds for Initiating Treatment of Eyes with Diabetic Macular Edema and Good Vision: Consideration of DRCR.Net Protocol V Results. Ophthalmol Retina. 2019 11; 3(11):917-919. PMID: 31699307.
      Citations: 2     Fields:    Translation:Humans
    187. Sadda SR, Campbell J, Dugel PU, Holekamp NM, Loewenstein A, Augustin AJ, Shih V, Xu X, Wykoff CC, Whitcup SM, Kiss S. Relationship between duration and extent of oedema and visual acuity outcome with ranibizumab in diabetic macular oedema: A post hoc analysis of Protocol I data. Eye (Lond). 2020 03; 34(3):480-490. PMID: 31320738; PMCID: PMC7042302.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    188. Liao DS, Grossi FV, El Mehdi D, Gerber MR, Brown DM, Heier JS, Wykoff CC, Singerman LJ, Abraham P, Grassmann F, Nuernberg P, Weber BHF, Deschatelets P, Kim RY, Chung CY, Ribeiro RM, Hamdani M, Rosenfeld PJ, Boyer DS, Slakter JS, Francois CG. Complement C3 Inhibitor Pegcetacoplan for Geographic Atrophy Secondary to Age-Related Macular Degeneration: A Randomized Phase 2 Trial. Ophthalmology. 2020 02; 127(2):186-195. PMID: 31474439.
      Citations: 59     Fields:    Translation:HumansCTClinical Trials
    189. Apolinario MA, Lampen SIR, Wong TP, Henry CR, Wykoff CC. Office-based intravitreal injection of expansile gas for management of macular hole in previously vitrectomized eyes. Am J Ophthalmol Case Rep. 2019 Sep; 15:100492. PMID: 31334383; PMCID: PMC6614528.
      Citations:    
    190. Puliafito CA, Wykoff CC. Looking ahead in retinal disease management: highlights of the 2019 angiogenesis, exudation and degeneration symposium. Int J Retina Vitreous. 2019; 5:22. PMID: 31161069; PMCID: PMC6542006.
      Citations: 3     
    191. Fan W, Nittala MG, Velaga SB, Hirano T, Wykoff CC, Ip M, Lampen SIR, van Hemert J, Fleming A, Verhoek M, Sadda SR. Distribution of Nonperfusion and Neovascularization on Ultrawide-Field Fluorescein Angiography in Proliferative Diabetic Retinopathy (RECOVERY Study): Report 1. Am J Ophthalmol. 2019 10; 206:154-160. PMID: 31078541.
      Citations: 14     Fields:    Translation:Humans
    192. Lynch SK, Lee K, Chen Z, Folk JC, Schmidt-Erfurth U, Gerendas BS, Wahle A, Wykoff CC, Abr?moff MD. Intravitreal Fluocinolone Acetonide May Decelerate Diabetic Retinal Neurodegeneration. Invest Ophthalmol Vis Sci. 2019 05 01; 60(6):2134-2139. PMID: 31100106; PMCID: PMC6528841.
      Citations: 6     Fields:    Translation:Humans
    193. Fang M, Fan W, Shi Y, Ip MS, Wykoff CC, Wang K, Falavarjani KG, Brown DM, van Hemert J, Sadda SR. Classification of Regions of Nonperfusion on Ultra-widefield Fluorescein Angiography in Patients with Diabetic Macular Edema. Am J Ophthalmol. 2019 10; 206:74-81. PMID: 30959003.
      Citations: 11     Fields:    Translation:Humans
    194. Chaturvedi R, Wannamaker KW, Riviere PJ, Khanani AM, Wykoff CC, Chao DL. Real-World Trends in Intravitreal Injection Practices among American Retina Specialists. Ophthalmol Retina. 2019 08; 3(8):656-662. PMID: 31133544; PMCID: PMC6684447.
      Citations: 5     Fields:    Translation:Humans
    195. Wykoff CC, Shah C, Dhoot D, Coleman HR, Thompson D, Du W, Baker K, Vitti R, Berliner AJ, Metzig C, Saroj N. Longitudinal Retinal Perfusion Status in Eyes with Diabetic Macular Edema Receiving Intravitreal Aflibercept or Laser in VISTA?Study. Ophthalmology. 2019 08; 126(8):1171-1180. PMID: 30946887.
      Citations: 16     Fields:    Translation:Humans
    196. Sahni J, Patel SS, Dugel PU, Khanani AM, Jhaveri CD, Wykoff CC, Hershberger VS, Pauly-Evers M, Sadikhov S, Szczesny P, Schwab D, Nogoceke E, Osborne A, Weikert R, Fauser S. Simultaneous Inhibition of Angiopoietin-2 and Vascular Endothelial Growth Factor-A with Faricimab in Diabetic Macular Edema: BOULEVARD Phase 2 Randomized Trial. Ophthalmology. 2019 08; 126(8):1155-1170. PMID: 30905643.
      Citations: 50     Fields:    Translation:HumansCTClinical Trials
    197. Wykoff CC, Rusakevich AM, Moshfeghi DM. Re: Adrean et?al.: Consistent long-term therapy of neovascular age-related macular degeneration managed by 50 or more anti-VEGF injections using a treat-extend-stop protocol (Ophthalmology. 2018;125:1047-1053). Ophthalmology. 2019 03; 126(3):e18-e19. PMID: 30803522.
      Citations:    Fields:    Translation:Humans
    198. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Randomized Trial of Treat and Extend Ranibizumab With and Without Navigated Laser Versus Monthly Dosing for Diabetic Macular Edema: TREX-DME 2-Year Outcomes. Am J Ophthalmol. 2019 06; 202:91-99. PMID: 30771333.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    199. Habot-Wilner Z, Noronha G, Wykoff CC. Suprachoroidally injected pharmacological agents for the treatment of chorio-retinal diseases: a targeted approach. Acta Ophthalmol. 2019 Aug; 97(5):460-472. PMID: 30702218.
      Citations: 15     Fields:    Translation:Humans
    200. Lee IT, Lampen SIR, Wong TP, Major JC, Wykoff CC. Fovea-sparing rhegmatogenous retinal detachments: impact of clinical factors including time to surgery on visual and anatomic outcomes. Graefes Arch Clin Exp Ophthalmol. 2019 May; 257(5):883-889. PMID: 30635720.
      Citations: 5     Fields:    Translation:Humans
    201. Aiello LP, Odia I, Glassman AR, Melia M, Jampol LM, Bressler NM, Kiss S, Silva PS, Wykoff CC, Sun JK, Diabetic Retinopathy Clinical Research Network. Comparison of Early Treatment Diabetic Retinopathy Study Standard 7-Field Imaging With Ultrawide-Field Imaging for Determining Severity of Diabetic Retinopathy. JAMA Ophthalmol. 2019 01 01; 137(1):65-73. PMID: 30347105; PMCID: PMC6439787.
      Citations: 29     Fields:    Translation:Humans
    202. Wykoff CC, Hariprasad SM, Zhou B. Innovation in Neovascular Age-Related Macular Degeneration: Consideration of Brolucizumab, Abicipar, and the Port Delivery System. Ophthalmic Surg Lasers Imaging Retina. 2018 12 01; 49(12):913-917. PMID: 30566697.
      Citations: 1     Fields:    Translation:Humans
    203. Lampen SIR, Khurana RN, Noronha G, Brown DM, Wykoff CC. Suprachoroidal Space Alterations Following Delivery of Triamcinolone Acetonide: Post-Hoc Analysis of the Phase 1/2 HULK Study of Patients With Diabetic Macular Edema. Ophthalmic Surg Lasers Imaging Retina. 2018 09 01; 49(9):692-697. PMID: 30222804.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    204. Amram AL, Mandviwala MM, Ou WC, Wykoff CC, Shah AR. Predictors of Visual Acuity Outcomes Following Vitrectomy for Idiopathic Macular Hole. Ophthalmic Surg Lasers Imaging Retina. 2018 08 01; 49(8):566-570. PMID: 30114300.
      Citations: 2     Fields:    Translation:Humans
    205. Wykoff CC, Eichenbaum DA, Roth DB, Hill L, Fung AE, Haskova Z. Ranibizumab Induces Regression of Diabetic Retinopathy in Most Patients at High Risk of Progression to Proliferative Diabetic Retinopathy. Ophthalmol Retina. 2018 10; 2(10):997-1009. PMID: 31047503.
      Citations: 20     Fields:    
    206. Wang K, Ghasemi Falavarjani K, Nittala MG, Sagong M, Wykoff CC, van Hemert J, Ip M, Sadda SR. Ultra-Wide-Field Fluorescein Angiography-Guided Normalization of Ischemic Index Calculation in Eyes With Retinal Vein Occlusion. Invest Ophthalmol Vis Sci. 2018 07 02; 59(8):3278-3285. PMID: 29971447.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    207. Eichenbaum DA, Buznego C, Weng CY, Dhoot DS, Wykoff CC, Sheth VS. When and How to Incorporate Steroids for Persistent Diabetic Macular Edema: A Discussion of Real-World Treatment Optimization Strategies. Ophthalmic Surg Lasers Imaging Retina. 2018 07 01; 49(7):S5-S15. PMID: 30021031.
      Citations: 4     Fields:    Translation:Humans
    208. Abdelfattah NS, Hariri AH, Al-Sheikh M, Pitetta S, Ebraheem A, Wykoff CC, Sadda SR, TREX-AMD Study Group. Topographic Correspondence of Macular Atrophy With Choroidal Neovascularization in Ranibizumab-treated Eyes of the TREX-AMD Trial. Am J Ophthalmol. 2018 08; 192:84-90. PMID: 29763612.
      Citations: 2     Fields:    Translation:Humans
    209. Wykoff CC, Khurana RN, Lampen SIR, Noronha G, Brown DM, Ou WC, Sadda SR, HULK Study Group. Suprachoroidal Triamcinolone Acetonide for Diabetic Macular Edema: The HULK Trial. Ophthalmol Retina. 2018 08; 2(8):874-877. PMID: 31047542.
      Citations: 14     Fields:    
    210. Payne JF, Clark WL, Bruce BB, Wykoff CC, Brown DM, Menke BM, Iverson SM, Allen KF, Boyer DS, Treat & Extend Protocol in Patients with Diabetic Macular Edema Study Group. Retinopathy Regression with Treat and Extend Ranibizumab for Diabetic Macular Edema. Ophthalmology. 2018 08; 125(8):1304-1306. PMID: 29729809.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    211. Sultan H, Wykoff CC, Shah AR. Five-Year Outcomes of Surgically Treated Symptomatic Epiretinal Membranes With and Without Internal Limiting Membrane Peeling. Ophthalmic Surg Lasers Imaging Retina. 2018 05 01; 49(5):296-302. PMID: 29772039.
      Citations: 4     Fields:    Translation:Humans
    212. Kwon S, Wykoff CC, Brown DM, van Hemert J, Fan W, Sadda SR. Changes in retinal ischaemic index correlate with recalcitrant macular oedema in retinal vein occlusion: WAVE study. Br J Ophthalmol. 2018 08; 102(8):1066-1071. PMID: 29699979.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    213. Naik S, Wykoff CC, Ou WC, Stevenson J, Gupta S, Shah AR. Identification of factors to increase efficacy of telemedicine screening for diabetic retinopathy in endocrinology practices using the Intelligent Retinal Imaging System (IRIS) platform. Diabetes Res Clin Pract. 2018 Jun; 140:265-270. PMID: 29649538.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    214. Ou WC, Lampen SIR, Wykoff CC. Longitudinal Quantification of Retinal Nonperfusion in the Macula of Eyes With Retinal Vein Occlusion Receiving Anti-VEGF Therapy: Secondary Analysis of the WAVE Randomized Trial. Ophthalmic Surg Lasers Imaging Retina. 2018 04 01; 49(4):258-264. PMID: 29664983.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    215. Jampol LM, Glassman AR, Liu D, Aiello LP, Bressler NM, Duh EJ, Quaggin S, Wells JA, Wykoff CC, Diabetic Retinopathy Clinical Research Network. Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema. Ophthalmology. 2018 07; 125(7):1054-1063. PMID: 29525602; PMCID: PMC6568257.
      Citations: 13     Fields:    Translation:Humans
    216. Wykoff CC, Clark WL, Nielsen JS, Brill JV, Greene LS, Heggen CL. Optimizing Anti-VEGF Treatment Outcomes for Patients with Neovascular Age-Related Macular Degeneration. J Manag Care Spec Pharm. 2018 Feb; 24(2-a Suppl):S3-S15. PMID: 29383980; PMCID: PMC10408401.
      Citations: 33     Fields:    Translation:HumansCells
    217. Fan W, Abdelfattah NS, Uji A, Lei J, Ip M, Sadda SR, Wykoff CC, TREX-AMD Study Group. Subfoveal choroidal thickness predicts macular atrophy in age-related macular degeneration: results from the TREX-AMD trial. Graefes Arch Clin Exp Ophthalmol. 2018 Mar; 256(3):511-518. PMID: 29374796.
      Citations: 8     Fields:    Translation:Humans
    218. Brown DM, Ou WC, Wong TP, Kim RY, Croft DE, Wykoff CC, DAVE Study Group. Targeted Retinal Photocoagulation for Diabetic Macular Edema with Peripheral Retinal Nonperfusion: Three-Year Randomized DAVE Trial. Ophthalmology. 2018 05; 125(5):683-690. PMID: 29336896.
      Citations: 17     Fields:    Translation:HumansCTClinical Trials
    219. Burgess FR, Radwan M, Croft DE, Wykoff CC. Diagnostic and Therapeutic Challenges. Retina. 2018 Jan; 38(1):203-206. PMID: 28207611.
      Citations:    Fields:    Translation:Humans
    220. Steinle NC, Lampen SIR, Wykoff CC. The Intersection of Diabetes Mellitus and Cataract Surgery: Current State of Management. Ophthalmol Retina. 2018 02; 2(2):83-85. PMID: 31047349.
      Citations:    Fields:    Translation:Humans
    221. Sadaka A, Iqbal C, Nazari H, Berry S, Wykoff CC, Humayun MS, Lee AG. Positive Visual Phenomena Following Implantation of the Argus II Retinal Prosthesis. Ophthalmic Surg Lasers Imaging Retina. 2017 12 01; 48(12):1022-1025. PMID: 29253307.
      Citations: 1     Fields:    Translation:Humans
    222. Brown DM, Wykoff CC. Intravitreal aflibercept for proliferative diabetic retinopathy. Lancet. 2017 11 11; 390(10108):2141. PMID: 29143753.
      Citations: 1     Fields:    Translation:Humans
    223. Ling J, Wykoff CC, Ch?vez-Barrios P. Subconjunctival Silicon Oil Cysts. Ophthalmol Retina. 2017 Nov - Dec; 1(6):560. PMID: 31047453.
      Citations:    Fields:    
    224. Campochiaro PA, Wykoff CC, Brown DM, Boyer DS, Barakat M, Taraborelli D, Noronha G, Tanzanite Study Group. Suprachoroidal Triamcinolone Acetonide for Retinal Vein Occlusion: Results of the Tanzanite Study. Ophthalmol Retina. 2018 04; 2(4):320-328. PMID: 31047241.
      Citations: 21     Fields:    
    225. Wykoff CC, Ou WC, Khurana RN, Brown DM, Lloyd Clark W, Boyer DS, ENDURANCE Study Group. Long-term outcomes with as-needed aflibercept in diabetic macular oedema: 2-year outcomes of the ENDURANCE extension study. Br J Ophthalmol. 2018 05; 102(5):631-636. PMID: 28814412.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    226. Wykoff CC, Ou WC, Croft DE, Payne JF, Brown DM, Clark WL, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Neovascular age-related macular degeneration management in the third year: final results from the TREX-AMD randomised trial. Br J Ophthalmol. 2018 04; 102(4):460-464. PMID: 28779006.
      Citations: 16     Fields:    Translation:HumansCTClinical Trials
    227. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Erratum. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care 2017;40:412-418. Diabetes Care. 2017 09; 40(9):1285. PMID: 28705833; PMCID: PMC5566277.
      Citations: 6     Fields:    
    228. Fan W, Wang K, Ghasemi Falavarjani K, Sagong M, Uji A, Ip M, Wykoff CC, Brown DM, van Hemert J, Sadda SR. Distribution of Nonperfusion Area on Ultra-widefield Fluorescein Angiography in Eyes With Diabetic Macular Edema: DAVE Study. Am J Ophthalmol. 2017 Aug; 180:110-116. PMID: 28579062.
      Citations: 29     Fields:    Translation:Humans
    229. Wykoff CC, Bansal AS, Akiyama K, Palmer JD, Chen E, Chang LK, Major JC, Wu C, Wang R, Croft DE, Wong TP, Khurana RN. THE ASSOCIATION OF EPIRETINAL MEMBRANE WITH MACULAR HOLE FORMATION AFTER RHEGMATOGENOUS RETINAL DETACHMENT REPAIR. Retina. 2017 Jun; 37(6):1073-1078. PMID: 27632712.
      Citations: 11     Fields:    Translation:Humans
    230. Ou WC, Brown DM, Payne JF, Wykoff CC. Relationship Between Visual Acuity and Retinal Thickness During Anti-Vascular Endothelial Growth Factor Therapy for Retinal Diseases. Am J Ophthalmol. 2017 Aug; 180:8-17. PMID: 28549848.
      Citations: 19     Fields:    Translation:Humans
    231. Wykoff CC. Impact of intravitreal pharmacotherapies including antivascular endothelial growth factor and corticosteroid agents on diabetic retinopathy. Curr Opin Ophthalmol. 2017 May; 28(3):213-218. PMID: 28376510.
      Citations: 14     Fields:    Translation:Humans
    232. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Erratum. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care 2017;40:412-418. Diabetes Care. 2017 06; 40(6):809. PMID: 28432087; PMCID: PMC5439409.
      Citations: 1     Fields:    
    233. Singh RP, Wykoff CC, Brown DM, Larsen M, Terasaki H, Silva FQ, Saroj N, Gibson A, Vitti R, Kayshap S, Berliner AJ, Zeitz O, Metzig C, Thompson D, Nguyen QD. Outcomes of Diabetic Macular Edema Patients by Baseline Hemoglobin A1c: Analyses from VISTA and VIVID. Ophthalmol Retina. 2017 Sep - Oct; 1(5):382-388. PMID: 31047565.
      Citations: 3     Fields:    
    234. Wykoff CC, Ou WC, Wang R, Brown DM, Cone C, Zamora D, Le RT, Sagong M, Wang K, Sadda SR, WAVE Study Group. Peripheral Laser for Recalcitrant Macular Edema Owing to Retinal Vein Occlusion: The WAVE Trial. Ophthalmology. 2017 06; 124(6):919-921. PMID: 28318636.
      Citations: 7     Fields:    Translation:HumansCTClinical Trials
    235. Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS, ENDURANCE Study Group. Reply. Am J Ophthalmol. 2017 05; 177:236-237. PMID: 28302270.
      Citations:    Fields:    
    236. Solomon SD, Chew E, Duh EJ, Sobrin L, Sun JK, VanderBeek BL, Wykoff CC, Gardner TW. Diabetic Retinopathy: A Position Statement by the American Diabetes Association. Diabetes Care. 2017 03; 40(3):412-418. PMID: 28223445; PMCID: PMC5402875.
      Citations: 204     Fields:    
    237. Wykoff CC, Ou WC, Brown DM, Croft DE, Wang R, Payne JF, Clark WL, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Randomized Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: 2-Year Results of the TREX-AMD Study. Ophthalmol Retina. 2017 Jul - Aug; 1(4):314-321. PMID: 31047517.
      Citations: 29     Fields:    
    238. Wykoff CC, Marcus DM, Midena E, Saroj N, Gibson A, Vitti R, Berliner AJ, Williams Liu Z, Zeitz O, Metzig C, Schmelter T, Heier JS, Korobelnik JF. Intravitreal Aflibercept Injection in Eyes With Substantial Vision Loss After Laser Photocoagulation for Diabetic Macular Edema: Subanalysis of the VISTA and VIVID Randomized Clinical Trials. JAMA Ophthalmol. 2017 Feb 01; 135(2):107-114. PMID: 28006063.
      Citations: 2     Fields:    
    239. Witkin AJ, Chang DF, Jumper JM, Charles S, Eliott D, Hoffman RS, Mamalis N, Miller KM, Wykoff CC. Vancomycin-Associated Hemorrhagic Occlusive Retinal Vasculitis: Clinical Characteristics of 36 Eyes. Ophthalmology. 2017 05; 124(5):583-595. PMID: 28110950.
      Citations: 31     Fields:    Translation:Humans
    240. Wykoff CC, Chakravarthy U, Campochiaro PA, Bailey C, Green K, Cunha-Vaz J. Long-term Effects of Intravitreal 0.19 mg Fluocinolone Acetonide Implant on Progression and Regression of Diabetic Retinopathy. Ophthalmology. 2017 04; 124(4):440-449. PMID: 28081945.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    241. Abdelfattah NS, Al-Sheikh M, Pitetta S, Mousa A, Sadda SR, Wykoff CC, Treat-and-Extend Age-Related Macular Degeneration Study Group. Macular Atrophy in Neovascular Age-Related Macular Degeneration with Monthly versus Treat-and-Extend Ranibizumab: Findings from the TREX-AMD Trial. Ophthalmology. 2017 02; 124(2):215-223. PMID: 27863845.
      Citations: 14     Fields:    Translation:Humans
    242. Payne JF, Wykoff CC, Clark WL, Bruce BB, Boyer DS, Brown DM, TREX-DME Study Group. Randomized Trial of Treat and Extend Ranibizumab with and without Navigated Laser for Diabetic Macular Edema: TREX-DME 1 Year Outcomes. Ophthalmology. 2017 01; 124(1):74-81. PMID: 27836430.
      Citations: 29     Fields:    Translation:Humans
    243. Corvi F, Lattanzio R, Miserocchi E, Querques L, Bandello F, Querques G, Croft DE, Wykoff CC. Diagnostic and Therapeutic Challenges. Retina. 2016 Nov; 36(11):2239-2245. PMID: 27322945.
      Citations:    Fields:    Translation:Humans
    244. Wykoff CC, Le RT, Khurana RN, Brown DM, Ou WC, Wang R, Clark WL, Boyer DS, ENDURANCE Study Group. Outcomes With As-Needed Aflibercept and Macular Laser Following the Phase III VISTA DME Trial: ENDURANCE 12-Month Extension Study. Am J Ophthalmol. 2017 Jan; 173:56-63. PMID: 27702624.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    245. Croft DE, Wykoff CC, Michels S, Chakravarthy U, Cruess AF. Regulatory Factors Influencing Usage of Retinal Pharmaceuticals: A Look Both Home and Abroad. Am J Ophthalmol. 2016 09; 169:xiv-xvi. PMID: 27485923.
      Citations:    Fields:    Translation:Humans
    246. Wykoff CC, Wang R, Chen E, Benz MS, Fish RH, Wong TP, Major JC, Brown DM, Schefler AC, Kim RY, O'Malley RE, Li AL. ENDOPHTHALMITIS AFTER INTRAVITREAL INJECTION: Role of Prophylactic Topical Ophthalmic Antibiotics. Retina. 2016 Jul; 36(7):1349-56. PMID: 26655622.
      Citations: 7     Fields:    Translation:HumansCells
    247. Wykoff CC, Elman MJ, Regillo CD, Ding B, Lu N, Stoilov I. Predictors of Diabetic Macular Edema Treatment Frequency with Ranibizumab During the Open-Label Extension of the RIDE and RISE Trials. Ophthalmology. 2016 08; 123(8):1716-1721. PMID: 27208982.
      Citations: 14     Fields:    Translation:HumansCTClinical Trials
    248. Wykoff CC, Hariprasad SM. DRCR Protocol-T: Reconciling 1- and 2-Year Data for Managing Diabetic Macular Edema. Ophthalmic Surg Lasers Imaging Retina. 2016 Apr 01; 47(4):308-12. PMID: 27065368.
      Citations: 6     Fields:    Translation:Humans
    249. Wykoff CC, Christie L, Croft DE, Major JC, Fish RH, Brown DM, Wang R. CHOROIDAL NEOVASCULARIZATION SECONDARY TO ALEXANDRITE LASER EXPOSURE. Retin Cases Brief Rep. 2016; 10(3):244-8. PMID: 26584328.
      Citations: 4     Fields:    Translation:Humans
    250. Wykoff CC, Brown DM, Wang R. GRANULAR HYPERREFLECTIVE SPECKS BY SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY AS SIGNS OF WEST NILE VIRUS INFECTION: THE STARDUST SIGN. Retin Cases Brief Rep. 2016; 10(4):349-53. PMID: 26674277.
      Citations:    Fields:    Translation:Humans
    251. Wykoff CC, Croft DE, Wong TP, RAVE Study Group, Brown DM. Reply: To PMID 24914476. Retina. 2015 Oct; 35(10):e61-3. PMID: 26398558.
      Citations:    Fields:    Translation:Humans
    252. Wykoff CC, Croft DE, Brown DM, Wang R, Payne JF, Clark L, Abdelfattah NS, Sadda SR, TREX-AMD Study Group. Prospective Trial of Treat-and-Extend versus Monthly Dosing for Neovascular Age-Related Macular Degeneration: TREX-AMD 1-Year Results. Ophthalmology. 2015 Dec; 122(12):2514-22. PMID: 26391465.
      Citations: 82     Fields:    Translation:HumansCTClinical Trials
    253. Wykoff CC, Schwartz SG, Adelman RA, Brucker AJ, Flynn HW. Primary rhegmatogenous retinal detachment repair: evidence supports an individualised approach. Br J Ophthalmol. 2015 Nov; 99(11):1451-3. PMID: 26347529.
      Citations: 3     Fields:    Translation:Humans
    254. Major JC, Wykoff CC, Croft DE, Wang R, Mariani AF, Lehmann AE, Brown DM. Aflibercept for pigment epithelial detachment for previously treated neovascular age-related macular degeneration. Can J Ophthalmol. 2015 Oct; 50(5):373-7. PMID: 26455973.
      Citations: 7     Fields:    Translation:Humans
    255. Croft DE, Wykoff CC, van Hemert J, Verhoek M, Brown DM. Not All Retina Is Created Equal: Metabolic Quantification of Ultra-Widefield Images. Ophthalmology. 2015 Dec; 122(12):2580-2. PMID: 26123089.
      Citations: 2     Fields:    Translation:HumansCells
    256. Wykoff CC, Hariprasad SM. Comparing aflibercept, bevacizumab, and ranibizumab for DME: analysis of DRCR Protocol T. Ophthalmic Surg Lasers Imaging Retina. 2015 Mar; 46(3):302-5. PMID: 25835307.
      Citations: 7     Fields:    Translation:Humans
    257. Wykoff CC, Brown DM, Croft DE, Major JC, Wong TP. Progressive retinal nonperfusion in ischemic central retinal vein occlusion. Retina. 2015 Jan; 35(1):43-7. PMID: 25102193.
      Citations: 11     Fields:    Translation:Humans
    258. Silva RA, Sridhar J, Miller D, Wykoff CC, Flynn HW. Exogenous fungal endophthalmitis: an analysis of isolates and susceptibilities to antifungal agents over a 20-year period (1990-2010). Am J Ophthalmol. 2015 Feb; 159(2):257-64.e1. PMID: 25449001.
      Citations: 14     Fields:    Translation:HumansAnimals
    259. Brown DM, Wykoff CC, Wong TP, Mariani AF, Croft DE, Schuetzle KL, RAVE Study Group. Ranibizumab in preproliferative (ischemic) central retinal vein occlusion: the rubeosis anti-VEGF (RAVE) trial. Retina. 2014 Sep; 34(9):1728-35. PMID: 24914476.
      Citations: 34     Fields:    Translation:HumansCTClinical Trials
    260. Campochiaro PA, Wykoff CC, Singer M, Johnson R, Marcus D, Yau L, Sternberg G. Monthly versus as-needed ranibizumab injections in patients with retinal vein occlusion: the SHORE study. Ophthalmology. 2014 Dec; 121(12):2432-42. PMID: 25060610.
      Citations: 24     Fields:    Translation:Humans
    261. Croft DE, van Hemert J, Wykoff CC, Clifton D, Verhoek M, Fleming A, Brown DM. Precise montaging and metric quantification of retinal surface area from ultra-widefield fundus photography and fluorescein angiography. Ophthalmic Surg Lasers Imaging Retina. 2014 Jul-Aug; 45(4):312-7. PMID: 25037013.
      Citations: 30     Fields:    Translation:Humans
    262. Campochiaro PA, Wykoff CC, Shapiro H, Rubio RG, Ehrlich JS. Neutralization of vascular endothelial growth factor slows progression of retinal nonperfusion in patients with diabetic macular edema. Ophthalmology. 2014 Sep; 121(9):1783-9. PMID: 24768239.
      Citations: 64     Fields:    Translation:HumansCTClinical Trials
    263. Wykoff CC, Brown DM, Maldonado ME, Croft DE. Aflibercept treatment for patients with exudative age-related macular degeneration who were incomplete responders to multiple ranibizumab injections (TURF trial). Br J Ophthalmol. 2014 Jul; 98(7):951-5. PMID: 24518078; PMCID: PMC4078682.
      Citations: 37     Fields:    Translation:Humans
    264. Major JC, Wykoff CC, Mariani AF, Chen E, Croft DE, Brown DM. Comparison of spectral-domain and time-domain optical coherence tomography in the detection of neovascular age-related macular degeneration activity. Retina. 2014 Jan; 34(1):48-54. PMID: 23764967.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    265. Wykoff CC, Flynn HW, Scott IU. What is the optimal timing for rhegmatogenous retinal detachment repair? JAMA Ophthalmol. 2013 Nov; 131(11):1399-400. PMID: 24008508.
      Citations: 4     Fields:    Translation:Humans
    266. Wykoff CC, Brown DM, Croft DE, Wong TP. Two Year SAVE Outcomes: 2.0 mg ranibizumab for recalcitrant neovascular AMD. Ophthalmology. 2013 Sep; 120(9):1945-6.e1. PMID: 24001533.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    267. Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Lasers for the treatment of intraocular tumors. Lasers Med Sci. 2013 May; 28(3):1025-34. PMID: 22302638.
      Citations: 5     Fields:    Translation:HumansPHPublic Health
    268. Wykoff CC, Brown DM, Chen E, Major JC, Croft DE, Mariani A, Wong TP, SAVE Study Group. SAVE (Super-dose anti-VEGF) trial: 2.0 mg ranibizumab for recalcitrant neovascular age-related macular degeneration: 1-year results. Ophthalmic Surg Lasers Imaging Retina. 2013 Mar-Apr; 44(2):121-6. PMID: 23510037.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    269. Mariani AF, Major JC, Brown DM, Wykoff CC, Benz MS, Kegley EN. Purtscher-like retinopathy associated with pemphigus vulgaris. Retin Cases Brief Rep. 2013; 7(4):304-6. PMID: 25383823.
      Citations:    Fields:    
    270. Bielory BP, Dubovy SR, Sinclair JC, Wykoff C, Murray TG. Pseudohypopyon as a clinical manifestation in metastatic lung carcinoma. Ophthalmic Surg Lasers Imaging. 2012 Feb 09; 43 Online:e1-4. PMID: 22320830.
      Citations: 1     Fields:    Translation:Humans
    271. Houston SK, Wykoff CC, Berrocal AM, Hess DJ, Murray TG. Laser treatment for retinopathy of prematurity. Lasers Med Sci. 2013 Feb; 28(2):683-92. PMID: 22134790.
      Citations: 11     Fields:    Translation:Humans
    272. Wykoff CC, Flynn HW, Rosenfeld PJ. Prophylaxis for endophthalmitis following intravitreal injection: antisepsis and antibiotics. Am J Ophthalmol. 2011 Nov; 152(5):717-9.e2. PMID: 22017840.
      Citations: 9     Fields:    Translation:HumansPHPublic Health
    273. Lingappan A, Wykoff CC, Albini TA, Miller D, Pathengay A, Davis JL, Flynn HW. Endogenous fungal endophthalmitis: causative organisms, management strategies, and visual acuity outcomes. Am J Ophthalmol. 2012 Jan; 153(1):162-6.e1. PMID: 21917234.
      Citations: 67     Fields:    Translation:HumansAnimals
    274. Wykoff CC, Murray TG, Markoe AM, Feun LG, Schefler AC, Gayer S. Preoperative evaluation for patients with choroidal/ciliary body melanomas: what is necessary? Am J Ophthalmol. 2011 Jun; 151(6):921-4. PMID: 21616209.
      Citations: 1     Fields:    Translation:Humans
    275. Wykoff CC, Flynn HW. Endophthalmitis after intravitreal injection: prevention and management. Retina. 2011 Apr; 31(4):633-5. PMID: 21836399.
      Citations: 4     Fields:    Translation:HumansCells
    276. Wykoff CC, Houston SK, Berrocal AM. Anti-vascular endothelial growth factor agents for pediatric retinal diseases. Int Ophthalmol Clin. 2011; 51(1):185-99. PMID: 21139484.
      Citations:    Fields:    Translation:Humans
    277. Wykoff CC, Flynn HW, Han DP. Allergy to povidone-iodine and cephalosporins: the clinical dilemma in ophthalmic use. Am J Ophthalmol. 2011 Jan; 151(1):4-6. PMID: 21163372.
      Citations: 6     Fields:    Translation:Humans
    278. Wykoff CC, Parrott MB, Flynn HW, Shi W, Miller D, Alfonso EC. Nosocomial acute-onset postoperative endophthalmitis at a university teaching hospital (2002-2009). Am J Ophthalmol. 2010 Sep; 150(3):392-398.e2. PMID: 20619391.
      Citations: 28     Fields:    Translation:Humans
    279. Wykoff CC, Smiddy WE, Mathen T, Schwartz SG, Flynn HW, Shi W. Fovea-sparing retinal detachments: time to surgery and visual outcomes. Am J Ophthalmol. 2010 Aug; 150(2):205-210.e2. PMID: 20541738.
      Citations: 12     Fields:    Translation:Humans
    280. Wykoff CC, Berrocal AM, Schefler AC, Uhlhorn SR, Ruggeri M, Hess D. Intraoperative OCT of a full-thickness macular hole before and after internal limiting membrane peeling. Ophthalmic Surg Lasers Imaging. 2010 Jan-Feb; 41(1):7-11. PMID: 20128563.
      Citations: 17     Fields:    Translation:Humans
    281. Sisk RA, Wykoff CC, Albini TA. Comment on "fundus autofluorescence and multiple evanescent white dot syndrome". Retina. 2009 Oct; 29(9):1377-8; author reply 1378-9. PMID: 19934830.
      Citations:    Fields:    Translation:Humans
    282. Wykoff CC, Albini TA, Couvillion SS, Dubovy SR, Davis JL. Intraocular cryptococcoma. Arch Ophthalmol. 2009 May; 127(5):700-2. PMID: 19433726.
      Citations: 2     Fields:    Translation:HumansAnimals
    283. Wykoff CC, Tutiven JL, Schaefer AM, Murray TG, Couvillion SS. Diffuse neonatal hemangiomatosis presenting as bilateral iris hemangiomas in an infant. Retin Cases Brief Rep. 2009; 3(3):279-82. PMID: 25389584.
      Citations:    Fields:    
    284. Dubovy SR, Barredo JC, Murray TG, Wykoff CC. Simultaneous presentation of retinoblastoma and morning glory disk anomaly. Retin Cases Brief Rep. 2009; 3(4):354-7. PMID: 25389845.
      Citations:    Fields:    
    285. Wykoff CC, Lujan BJ, Rosenfeld PJ. Photodynamic therapy of bullous central serous chorioretinopathy with subretinal exudate and a tear of the retinal pigment epithelium. Retin Cases Brief Rep. 2009; 3(2):218-23. PMID: 25391081.
      Citations: 2     Fields:    
    286. Wykoff CC, Lam BL, Brathwaite CD, Biegel JA, McKeown CA, Rosenblum MK, Allewelt HB, Sandberg DI. Atypical teratoid/rhabdoid tumor arising from the third cranial nerve. J Neuroophthalmol. 2008 Sep; 28(3):207-11. PMID: 18769285; PMCID: PMC2839362.
      Citations: 6     Fields:    Translation:Humans
    287. Wykoff CC, Flynn HW, Miller D, Scott IU, Alfonso EC. Exogenous fungal endophthalmitis: microbiology and clinical outcomes. Ophthalmology. 2008 Sep; 115(9):1501-7, 1507.e1-2. PMID: 18486220.
      Citations: 47     Fields:    Translation:HumansAnimals
    288. Wykoff CC, Pineda R. Myopic laser in situ keratomileusis in eyes with thick corneas. J Cataract Refract Surg. 2006 May; 32(5):900-1. PMID: 16765817.
      Citations:    Fields:    Translation:Humans
    289. Stolze IP, Tian YM, Appelhoff RJ, Turley H, Wykoff CC, Gleadle JM, Ratcliffe PJ. Genetic analysis of the role of the asparaginyl hydroxylase factor inhibiting hypoxia-inducible factor (FIH) in regulating hypoxia-inducible factor (HIF) transcriptional target genes [corrected]. J Biol Chem. 2004 Oct 08; 279(41):42719-25. PMID: 15302861.
      Citations: 68     Fields:    Translation:HumansAnimalsCells
    290. Turley H, Wykoff CC, Troup S, Watson PH, Gatter KC, Harris AL. The hypoxia-regulated transcription factor DEC1 (Stra13, SHARP-2) and its expression in human tissues and tumours. J Pathol. 2004 Jul; 203(3):808-13. PMID: 15221940.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    291. Wykoff CC, Sotiriou C, Cockman ME, Ratcliffe PJ, Maxwell P, Liu E, Harris AL. Gene array of VHL mutation and hypoxia shows novel hypoxia-induced genes and that cyclin D1 is a VHL target gene. Br J Cancer. 2004 Mar 22; 90(6):1235-43. PMID: 15026807; PMCID: PMC2409644.
      Citations:    
    292. Giatromanolaki A, Koukourakis MI, Sivridis E, Turley H, Wykoff CC, Gatter KC, Harris AL. DEC1 (STRA13) protein expression relates to hypoxia- inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol. 2003 Jun; 200(2):222-8. PMID: 12754744.
      Citations: 32     Fields:    Translation:Humans
    293. Watson PH, Chia SK, Wykoff CC, Han C, Leek RD, Sly WS, Gatter KC, Ratcliffe P, Harris AL. Carbonic anhydrase XII is a marker of good prognosis in invasive breast carcinoma. Br J Cancer. 2003 Apr 07; 88(7):1065-70. PMID: 12671706; PMCID: PMC2376369.
      Citations: 54     Fields:    Translation:Humans
    294. Swinson DE, Jones JL, Richardson D, Wykoff C, Turley H, Pastorek J, Taub N, Harris AL, O'Byrne KJ. Carbonic anhydrase IX expression, a novel surrogate marker of tumor hypoxia, is associated with a poor prognosis in non-small-cell lung cancer. J Clin Oncol. 2003 Feb 01; 21(3):473-82. PMID: 12560438.
      Citations: 108     Fields:    Translation:HumansCells
    295. Adeyinka A, Emberley E, Niu Y, Snell L, Murphy LC, Sowter H, Wykoff CC, Harris AL, Watson PH. Analysis of gene expression in ductal carcinoma in situ of the breast. Clin Cancer Res. 2002 Dec; 8(12):3788-95. PMID: 12473591.
      Citations: 26     Fields:    Translation:HumansCells
    296. Mandriota SJ, Turner KJ, Davies DR, Murray PG, Morgan NV, Sowter HM, Wykoff CC, Maher ER, Harris AL, Ratcliffe PJ, Maxwell PH. HIF activation identifies early lesions in VHL kidneys: evidence for site-specific tumor suppressor function in the nephron. Cancer Cell. 2002 Jun; 1(5):459-68. PMID: 12124175.
      Citations: 233     Fields:    Translation:Humans
    297. Turner KJ, Crew JP, Wykoff CC, Watson PH, Poulsom R, Pastorek J, Ratcliffe PJ, Cranston D, Harris AL. The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Br J Cancer. 2002 Apr 22; 86(8):1276-82. PMID: 11953885; PMCID: PMC2375338.
      Citations: 37     Fields:    Translation:HumansCells
    298. Giatromanolaki A, Koukourakis MI, Sivridis E, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Expression of hypoxia-inducible carbonic anhydrase-9 relates to angiogenic pathways and independently to poor outcome in non-small cell lung cancer. Cancer Res. 2001 Nov 01; 61(21):7992-8. PMID: 11691824.
      Citations: 124     Fields:    Translation:HumansCells
    299. Koukourakis MI, Giatromanolaki A, Sivridis E, Simopoulos K, Pastorek J, Wykoff CC, Gatter KC, Harris AL. Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy. Clin Cancer Res. 2001 Nov; 7(11):3399-403. PMID: 11705854.
      Citations: 61     Fields:    Translation:Humans
    300. Chia SK, Wykoff CC, Watson PH, Han C, Leek RD, Pastorek J, Gatter KC, Ratcliffe P, Harris AL. Prognostic significance of a novel hypoxia-regulated marker, carbonic anhydrase IX, in invasive breast carcinoma. J Clin Oncol. 2001 Aug 15; 19(16):3660-8. PMID: 11504747.
      Citations: 157     Fields:    Translation:HumansAnimals
    301. Beasley NJ, Wykoff CC, Watson PH, Leek R, Turley H, Gatter K, Pastorek J, Cox GJ, Ratcliffe P, Harris AL. Carbonic anhydrase IX, an endogenous hypoxia marker, expression in head and neck squamous cell carcinoma and its relationship to hypoxia, necrosis, and microvessel density. Cancer Res. 2001 Jul 01; 61(13):5262-7. PMID: 11431368.
      Citations: 73     Fields:    Translation:HumansCells
    302. Wykoff CC, Beasley N, Watson PH, Campo L, Chia SK, English R, Pastorek J, Sly WS, Ratcliffe P, Harris AL. Expression of the hypoxia-inducible and tumor-associated carbonic anhydrases in ductal carcinoma in situ of the breast. Am J Pathol. 2001 Mar; 158(3):1011-9. PMID: 11238049; PMCID: PMC1850356.
      Citations: 87     Fields:    Translation:HumansCells
    303. Wykoff CC, Pugh CW, Harris AL, Maxwell PH, Ratcliffe PJ. The HIF pathway: implications for patterns of gene expression in cancer. Novartis Found Symp. 2001; 240:212-25; discussion 225-31. PMID: 11727931.
      Citations: 14     Fields:    Translation:HumansCells
    304. Wykoff CC, Beasley NJ, Watson PH, Turner KJ, Pastorek J, Sibtain A, Wilson GD, Turley H, Talks KL, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res. 2000 Dec 15; 60(24):7075-83. PMID: 11156414.
      Citations: 482     Fields:    Translation:HumansCells
    305. Wykoff CC, Pugh CW, Maxwell PH, Harris AL, Ratcliffe PJ. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling. Oncogene. 2000 Dec 14; 19(54):6297-305. PMID: 11175344.
      Citations: 71     Fields:    Translation:Cells
    306. Maxwell PH, Wiesener MS, Chang GW, Clifford SC, Vaux EC, Cockman ME, Wykoff CC, Pugh CW, Maher ER, Ratcliffe PJ. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 1999 May 20; 399(6733):271-5. PMID: 10353251.
      Citations: 1910     Fields:    Translation:HumansCells
    307. Pugh CW, Chang GW, Cockman M, Epstein AC, Gleadle JM, Maxwell PH, Nicholls LG, O'Rourke JF, Ratcliffe PJ, Raybould EC, Tian YM, Wiesener MS, Wood M, Wykoff CC, Yeates KM. Regulation of gene expression by oxygen levels in mammalian cells. Adv Nephrol Necker Hosp. 1999; 29:191-206. PMID: 10561745.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    308. Engelman JA, Wykoff CC, Yasuhara S, Song KS, Okamoto T, Lisanti MP. Recombinant expression of caveolin-1 in oncogenically transformed cells abrogates anchorage-independent growth. J Biol Chem. 1997 Jun 27; 272(26):16374-81. PMID: 9195944.
      Citations: 94     Fields:    Translation:AnimalsCells
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