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FRANCESCA POLVERINO

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address6501 Fannin St
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Polverino F, Woodruff PG. Radiomultiomics: pioneering precision medicine for severe asthma. Eur Respir J. 2024 Nov; 64(5). PMID: 39572207.
      Citations:    Fields:    
    2. Olvera N, S?nchez-Valle J, N??ez-Carpintero I, Rojas-Quintero J, Noell G, Casas-Recasens S, Faiz A, Hansbro P, Guirao A, Lepore R, Cirillo D, Agust? A, Polverino F, Valencia A, Faner R, Olvera N, S?nchez-Valle J, N??ez-Carpintero I, Rojas-Quintero J, Noell G, Casas-Recasens S, Faiz A, Hansbro P, Guirao A, Lepore R, Cirillo D, Agust? A, Polverino F, Valencia A, Faner R. Lung Tissue Multilayer Network Analysis Uncovers the Molecular Heterogeneity of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 Nov 15; 210(10):1219-1229. PMID: 38626356; PMCID: PMC11568432.
      Citations: 1     Fields:    Translation:Humans
    3. Polverino F, Bhutani M, Zabert G, Fernandes FLA, Czischke K, Pereira Ferreira LF, Szabo L, Wisnivesky JP, Dalcolmo MP, Celed?n JC, Polverino F, Bhutani M, Zabert G, Fernandes FLA, Czischke K, Pereira Ferreira LF, Szabo L, Wisnivesky JP, Dalcolmo MP, Celed?n JC. Access to Treatment for Chronic Obstructive Pulmonary Disease in the Americas: A Call for Action. A Joint Perspective from the Brazilian Thoracic Society, Canadian Thoracic Society, Latin American Thoracic Society, and the American Thoracic Society. Ann Am Thorac Soc. 2024 Nov; 21(11):1463-1470. PMID: 39083678; PMCID: PMC11568495.
      Citations:    Fields:    Translation:Humans
    4. Summers B, Kim K, Trivedi A, Lu TM, Houghton S, Palmer-Johnson J, Quintero JR, Cala-Garcia J, Pannellini T, Polverino F, Lis R, Reed HO. Mice with Lymphatic Dysfunction Develop Pathogenic Lung Tertiary Lymphoid Organs that Model an Autoimmune Emphysema Phenotype of COPD. Am J Physiol Lung Cell Mol Physiol. 2024 Oct 22. PMID: 39437762.
      Citations:    Fields:    
    5. Rojas-Quintero J, Ochsner SA, Lee HS, Cong C, Cohen AW, Colborg AS, Tsoyi K, Basil MC, Cantu E, Rosas IO, McKenna NJ, Est?par RS, Barjaktarevic I, Wilson AA, Polverino F. Skewed adaptive immune responses are involved in AATD emphysema. Eur Respir J. 2024 Oct 10. PMID: 39401853.
      Citations:    Fields:    
    6. Moll M, Xu Z, Boueiz A, Ryu MH, Silverman EK, Cho MH, Hersh CP, Sauler M, Polverino F, Kinney GL, Curtis JL, Crotty-Alexander LE, Vollmers C, Castaldi PJ, Moll M, Xu Z, Boueiz A, Ryu MH, Silverman EK, Cho MH, Hersh CP, Sauler M, Polverino F, Kinney GL, Curtis JL, Crotty-Alexander LE, Vollmers C, Castaldi PJ. B cell immune repertoire sequencing in tobacco cigarette smoking, vaping, and chronic obstructive pulmonary disease in the COPDGene cohort. medRxiv. 2024 Oct 08. PMID: 39417147; PMCID: PMC11483011.
      Citations:    
    7. Yildirim A?, Conlon TM, Adcock IM, Gosens R, Lehmann M, Kapellos TS, Tesfaigzi Y, Polverino F, Sauler M, Wasnick R, Neptune ER. COPD-iNET: a call to the lung community for action to combat the global epidemic of COPD. Eur Respir J. 2024 Sep; 64(3). PMID: 39326903.
      Citations:    Fields:    Translation:HumansPHPublic Health
    8. Polverino F, Sin DD, Sin DD. Type 2 airway inflammation in COPD. Eur Respir J. 2024 May; 63(5). PMID: 38485148.
      Citations: 1     Fields:    Translation:HumansCells
    9. Soriano JB, Polverino F. Sexual activity and respiratory disease: A systematic review. Respir Med. 2024 07; 228:107665. PMID: 38768665.
      Citations:    Fields:    Translation:Humans
    10. Polverino F. Clearing the Air: Innovations in Imaging for Early Detection and Management of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 04 15; 209(8):1042-1043. PMID: 38227941; PMCID: PMC11531217.
      Citations:    Fields:    Translation:Humans
    11. Polverino F, Mora A. Alveolar Epithelial Cell Dysfunction in Idiopathic Pulmonary Fibrosis Linked to Lipid Alterations: Therapeutic Implications. Am J Respir Cell Mol Biol. 2024 Apr; 70(4):233-234. PMID: 38271680; PMCID: PMC11478126.
      Citations:    Fields:    Translation:HumansCells
    12. Zhang H, Mulqueen RM, Iannuzo N, Farrera DO, Polverino F, Galligan JJ, Ledford JG, Adey AC, Cusanovich DA. txci-ATAC-seq: a massive-scale single-cell technique to profile chromatin accessibility. Genome Biol. 2024 03 22; 25(1):78. PMID: 38519979; PMCID: PMC10958877.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    13. Rojas-Quintero J, Ochsner SA, New F, Divakar P, Yang CX, Wu TD, Robinson J, Chandrashekar DS, Banovich NE, Rosas IO, Sauler M, Kheradmand F, Gaggar A, Margaroli C, San Jose Estepar R, McKenna NJ, Polverino F. Spatial Transcriptomics Resolve an Emphysema-Specific Lymphoid Follicle B Cell Signature in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2024 01 01; 209(1):48-58. PMID: 37934672; PMCID: PMC10870877.
      Citations:    Fields:    Translation:Humans
    14. Rojas-Quintero J, Ochsner SA, New F, Divakar P, Yang CX, Wu TD, Robinson J, Shimoga Chandrashekar D, Banovich NE, Rosas IO, Sauler M, Kheradmand F, Gaggar A, Margaroli C, San Jose Estepar R, McKenna NJ, Polverino F. Spatial Transcriptomics Resolve an Emphysema-specific Lymphoid Follicle B Cell Signature in COPD. Am J Respir Crit Care Med. 2023 Dec 08. PMID: 38064378.
      Citations:    Fields:    
    15. Iannuzo N, Welfley H, Li NC, Johnson MDL, Rojas-Quintero J, Polverino F, Guerra S, Li X, Cusanovich DA, Langlais PR, Ledford JG. CC16 drives VLA-2-dependent SPLUNC1 expression. Front Immunol. 2023; 14:1277582. PMID: 38053993; PMCID: PMC10694244.
      Citations:    Fields:    Translation:HumansAnimalsCells
    16. Liu G, Haw TJ, Starkey MR, Philp AM, Pavlidis S, Nalkurthi C, Nair PM, Gomez HM, Hanish I, Hsu AC, Hortle E, Pickles S, Rojas-Quintero J, Estepar RSJ, Marshall JE, Kim RY, Collison AM, Mattes J, Idrees S, Faiz A, Hansbro NG, Fukui R, Murakami Y, Cheng HS, Tan NS, Chotirmall SH, Horvat JC, Foster PS, Oliver BG, Polverino F, Ieni A, Monaco F, Caramori G, Sohal SS, Bracke KR, Wark PA, Adcock IM, Miyake K, Sin DD, Hansbro PM. TLR7 promotes smoke-induced experimental lung damage through the activity of mast cell tryptase. Nat Commun. 2023 Nov 14; 14(1):7349. PMID: 37963864; PMCID: PMC10646046.
      Citations:    Fields:    Translation:HumansAnimals
    17. Soriano JB, Polverino F. Sex and gender in COPD and asthma. Eur Respir J. 2023 Nov; 62(5). PMID: 37945042.
      Citations:    Fields:    
    18. Summers B, Kim K, Lu TM, Houghton S, Trivedi A, Quintero JR, Cala-Garcia J, Pannellini T, Polverino F, Lis R, Reed HO. Lymphatic Dysfunction Models an Autoimmune Emphysema Phenotype of Chronic Obstructive Pulmonary Disease. bioRxiv. 2023 Nov 02. PMID: 37961242; PMCID: PMC10635025.
      Citations:    
    19. Tesfaigzi Y, Curtis JL, Petrache I, Polverino F, Kheradmand F, Adcock IM, Rennard SI. Does Chronic Obstructive Pulmonary Disease Originate from Different Cell Types? Am J Respir Cell Mol Biol. 2023 11; 69(5):500-507. PMID: 37584669; PMCID: PMC10633838.
      Citations: 1     Fields:    Translation:HumansCells
    20. Polverino M, Sampaolo S, Capuozzo A, Fasolino M, Aliberti M, Satta E, Santoriello C, Orengo JP, Polverino F. Respiratory Function Changes as Early Signs of Amyotrophic Lateral Sclerosis. Respiration. 2023; 102(11):919-923. PMID: 37844546; PMCID: PMC10842422.
      Citations: 1     Fields:    Translation:Humans
    21. Divo MJ, Liu C, Castaldi PJ, Celli BR, Tesfaigzi Y, Polverino F. From pre-COPD to COPD: a Simple, Low cost and easy to IMplement (SLIM) risk calculator. Eur Respir J. 2023 09; 62(3). PMID: 37678951; PMCID: PMC10533946.
      Citations: 2     Fields:    Translation:Humans
    22. Celada SI, Lim CX, Carisey AF, Ochsner SA, Arce Deza CF, Rexie P, Poli De Frias F, Cardenas-Castillo R, Polverino F, Tsoyi K, McKenna NJ, Kheradmand F, Weichhart T, Rosas IO, Van Kaer L, Celada LJ, Hengstschl?ger M. SHP2 promotes sarcoidosis severity by inhibiting SKP2-targeted ubiquitination of TBET in CD8+ T cells. Sci Transl Med. 2023 09 13; 15(713):eade2581. PMID: 37703351; PMCID: PMC11126869.
      Citations:    Fields:    Translation:HumansAnimalsCells
    23. Lingappan K, Olutoye OO, Cantu A, Cantu Gutierrez ME, Cortes-Santiago N, Hammond JD, Gilley J, Quintero JR, Li H, Polverino F, Gleghorn JP, Keswani SG. Molecular insights using spatial transcriptomics of the distal lung in congenital diaphragmatic hernia. Am J Physiol Lung Cell Mol Physiol. 2023 10 01; 325(4):L477-L486. PMID: 37605849; PMCID: PMC10639013.
      Citations:    Fields:    Translation:HumansCells
    24. Tanyaratsrisakul S, Dy ABC, Polverino F, Numata M, Ledford JG. Myeloid-associated differentiation marker is associated with type 2 asthma and is upregulated by human rhinovirus infection. Front Immunol. 2023; 14:1237683. PMID: 37638015; PMCID: PMC10450947.
      Citations:    Fields:    Translation:HumansAnimalsCells
    25. Bracke KR, Polverino F. Blunted adaptive immune responses and acute exacerbations of COPD: breaking the code. Eur Respir J. 2023 08; 62(2). PMID: 37536726.
      Citations:    Fields:    Translation:HumansCells
    26. Polverino F, Kalhan R. Leveraging Omics to Predict Chronic Obstructive Pulmonary Disease Exacerbations: The "Immunome". Am J Respir Crit Care Med. 2023 08 01; 208(3):220-222. PMID: 37352489; PMCID: PMC10395726.
      Citations:    Fields:    Translation:Humans
    27. Polverino F. Genetic Susceptibility to Chronic Obstructive Pulmonary Disease and Idiopathic Pulmonary Fibrosis: The Missing Link? Am J Respir Cell Mol Biol. 2023 05; 68(5):482-484. PMID: 36753719; PMCID: PMC10174170.
      Citations:    Fields:    Translation:Humans
    28. Polverino F, Sciurba F. Lung volume reduction in COPD: scope or surgery. Eur Respir J. 2023 04; 61(4). PMID: 37105590.
      Citations:    Fields:    Translation:Humans
    29. Rojas-Quintero J, Laucho-Contreras ME, Wang X, Fucci QA, Burkett PR, Kim SJ, Zhang D, Tesfaigzi Y, Li Y, Bhashyam AR, Li Z, Khamas H, Celli B, Pilon AL, Polverino F, Owen CA. CC16 augmentation reduces exaggerated COPD-like disease in Cc16-deficient mice. JCI Insight. 2023 03 22; 8(6). PMID: 36787195; PMCID: PMC10070105.
      Citations: 1     Fields:    Translation:HumansAnimals
    30. Polverino F, Sampaolo S, Capuozzo A, Fasolino M, Aliberti M, Satta E, Santoriello C, Polverino M. Diagnosis of amyotrophic lateral sclerosis by respiratory function test. Multidiscip Respir Med. 2023 Jan 17; 18(1):941. PMID: 38322130; PMCID: PMC10782889.
      Citations:    
    31. Polverino F, Mirra D, Yang CX, Esposito R, Spaziano G, Rojas-Quintero J, Sgambato M, Piegari E, Cozzolino A, Cione E, Gallelli L, Capuozzo A, Santoriello C, Berrino L, de-Torres JP, Hackett TL, Polverino M, D'Agostino B. Similar programmed death ligand 1 (PD-L1) expression profile in patients with mild COPD and lung cancer. Sci Rep. 2022 12 27; 12(1):22402. PMID: 36575294; PMCID: PMC9792927.
      Citations:    
    32. Polverino F, Stern DA, Snyder EM, Wheatley-Guy C, Bhatt SP, Martinez FD, Guerra S, Morgan WJ. Lower respiratory illnesses in childhood are associated with the presence of air trapping in early adulthood. Respir Med. 2023 01; 206:107062. PMID: 36508986; PMCID: PMC10389168.
      Citations: 1     Fields:    Translation:Humans
    33. Polverino F, Celli B. Challenges in the Pharmacotherapy of COPD Subtypes. Arch Bronconeumol. 2023 05; 59(5):284-287. PMID: 36464514.
      Citations:    Fields:    Translation:Humans
    34. Pederson WP, Ellerman LM, Sandoval EC, Boitano S, Frye JB, Doyle KP, Brooks HL, Polverino F, Ledford JG. Development of a Novel Mouse Model of Menopause-associated Asthma. Am J Respir Cell Mol Biol. 2022 11; 67(5):605-609. PMID: 36318015; PMCID: PMC9651199.
      Citations: 1     Fields:    Translation:Animals
    35. Polverino F, Celli BR. Selecting the Right Patient: The Achilles Heel of COPD Clinical Trials. Am J Respir Crit Care Med. 2022 10 15; 206(8):1051-1052. PMID: 35834808; PMCID: PMC9801990.
      Citations:    Fields:    
    36. Polverino F, Marin JM. The lower respiratory tract: the hot spot for chronic fixed airflow limitation. Eur Respir J. 2022 10; 60(4). PMID: 36202404.
      Citations:    Fields:    Translation:Humans
    37. Divo MJ, Marin JM, Casanova C, Cabrera Lopez C, Pinto-Plata VM, Marin-Oto M, Polverino F, de-Torres JP, Billheimer D, Celli BR, BODE Collaborative Group. Comorbidities and mortality risk in adults younger than 50?years of age with chronic obstructive pulmonary disease. Respir Res. 2022 Sep 27; 23(1):267. PMID: 36167533; PMCID: PMC9516817.
      Citations: 3     Fields:    Translation:Humans
    38. Polverino F, Washko GR, Covar RA, Hysinger EB, Hackett TL, Bhatt SP, Brusselle G, Dharmage SC. The low flyers: persistent airflow limitation in young adults. Lancet Respir Med. 2022 09; 10(9):819-822. PMID: 35850124.
      Citations:    Fields:    
    39. Yang CX, Tomchaney M, Landecho MF, Zamacona BR, Marin Oto M, Zulueta J, Malo J, Knoper S, Contoli M, Papi A, Vasilescu DM, Sauler M, Straub C, Tan C, Martinez FD, Bhattacharya D, Rosas IO, Kheradmand F, Hackett TL, Polverino F. Lung Spatial Profiling Reveals a T Cell Signature in COPD Patients with Fatal SARS-CoV-2 Infection. Cells. 2022 06 07; 11(12). PMID: 35740993; PMCID: PMC9220844.
      Citations:    Fields:    Translation:HumansCells
    40. Polverino F. Adaptive immune responses and protein homeostasis in COPD: the immunoproteasome. Eur Respir J. 2022 03; 59(3). PMID: 35241460.
      Citations:    Fields:    Translation:HumansCells
    41. Casanova C, Divo M, Polverino F, Celli BR, Ezponda A, Mar?n-Oto M, Cabrera C, Mar?n JM, Bastarrika G, Pinto-Plata V, Martin-Palmero ?, de Torres JP. Chest CT-assessed comorbidities and all-cause mortality risk in COPD patients in the BODE cohort. Respirology. 2022 04; 27(4):286-293. PMID: 35132732; PMCID: PMC9303420.
      Citations: 1     Fields:    Translation:Humans
    42. Satta E, Alfarone C, De Maio A, Gentile S, Romano C, Polverino M, Polverino F. Kidney and lung in pathology: mechanisms and clinical implications. Multidiscip Respir Med. 2022 Jan 12; 17(2):819. PMID: 35127080; PMCID: PMC8791019.
      Citations:    
    43. Dieffenbach PB, Mallarino Haeger C, Rehman R, Corcoran AM, Coronata AMF, Vellarikkal SK, Chrobak I, Waxman AB, Vitali SH, Sholl LM, Padera RF, Lagares D, Polverino F, Owen CA, Fredenburgh LE. A Novel Protective Role for Matrix Metalloproteinase-8 in the Pulmonary Vasculature. Am J Respir Crit Care Med. 2021 12 15; 204(12):1433-1451. PMID: 34550870; PMCID: PMC8865706.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    44. Iannuzo N, Insel M, Marshall C, Pederson WP, Addison KJ, Polverino F, Guerra S, Ledford JG. CC16 Deficiency in the Context of Early-Life Mycoplasma pneumoniae Infection Results in Augmented Airway Responses in Adult Mice. Infect Immun. 2022 02 17; 90(2):e0054821. PMID: 34780280; PMCID: PMC8853681.
      Citations:    Fields:    Translation:AnimalsCells
    45. Rojas-Quintero J, Polverino F. Tweaking lung inflammation in COPD: the "mirky" ways of miRNAs. Am J Physiol Lung Cell Mol Physiol. 2021 12 01; 321(6):L1089-L1090. PMID: 34730035; PMCID: PMC8715016.
      Citations:    Fields:    Translation:Humans
    46. Polverino F, Soriano JB. Asthma and Chronic Obstructive Pulmonary Disease: Just Old Friends or Relatives? Am J Respir Crit Care Med. 2021 10 01; 204(7):870-871. PMID: 34190677; PMCID: PMC8528531.
      Citations:    Fields:    Translation:Humans
    47. Polverino F, Wu TD, Rojas-Quintero J, Wang X, Mayo J, Tomchaney M, Tram J, Packard S, Zhang D, Cleveland KH, Owen CA, Fawzy A, Kinney GL, Hersh CP, Hansel NN, Doubleday K, Sauler M, Tesfaigzi Y, Ledford JG, Zmijewski J, Konhilas J, Langlais PR, Schnellmann R, Rahman I, McCormack M, Celli B, Cordoba-Lanus E, Casanova C. Metformin: Experimental and Clinical Evidence for a Potential Role in Emphysema Treatment. Am J Respir Crit Care Med. 2021 09 15; 204(6):651-666. PMID: 34033525; PMCID: PMC8521702.
      Citations: 10     Fields:    Translation:HumansAnimals
    48. Tomchaney M, Contoli M, Mayo J, Baraldo S, Li S, Cabel CR, Bull DA, Lick S, Malo J, Knoper S, Kim SS, Tram J, Rojas-Quintero J, Kraft M, Ledford JG, Tesfaigzi Y, Martinez FD, Thorne CA, Kheradmand F, Campos SK, Papi A, Polverino F. Paradoxical effects of cigarette smoke and COPD on SARS-CoV-2 infection and disease. BMC Pulm Med. 2021 Aug 23; 21(1):275. PMID: 34425811; PMCID: PMC8381712.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    49. Johnson MDL, Younis US, Menghani SV, Addison KJ, Whalen M, Pilon AL, Cress AE, Polverino F, Romanoski CE, Kraft M, Martinez FD, Guerra S, Ledford JG. CC16 Binding to a4?1 Integrin Protects against Mycoplasma pneumoniae Infection. Am J Respir Crit Care Med. 2021 06 01; 203(11):1410-1418. PMID: 33326355; PMCID: PMC8456541.
      Citations: 4     Fields:    Translation:AnimalsCells
    50. Li Y, Zhang L, Polverino F, Guo F, Hao Y, Lao T, Xu S, Li L, Pham B, Owen CA, Zhou X. Hedgehog interacting protein (HHIP) represses airway remodeling and metabolic reprogramming in COPD-derived airway smooth muscle cells. Sci Rep. 2021 04 27; 11(1):9074. PMID: 33907231; PMCID: PMC8079715.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    51. Polverino F, Kheradmand F. COVID-19, COPD, and AECOPD: Immunological, Epidemiological, and Clinical Aspects. Front Med (Lausanne). 2020; 7:627278. PMID: 33537336; PMCID: PMC7847987.
      Citations: 9     
    52. Tomchaney M, Contoli M, Mayo J, Baraldo S, Shuaizhi L, Cabel CR, Bull DA, Lick S, Malo J, Knoper S, Kim SS, Tram J, Rojas-Quintero J, Kraft M, Ledford J, Tesfaigzi Y, Martinez FD, Thorne CA, Kheradmand F, Campos SK, Papi A, Polverino F. Paradoxical effects of cigarette smoke and COPD on SARS-CoV2 infection and disease. bioRxiv. 2020 Dec 07. PMID: 33330864; PMCID: PMC7743068.
      Citations: 1     
    53. Polverino F, Stern DA, Balestro E, Bassetti M, Candelli M, Cirillo B, Contoli M, Corsico A, D'Amico F, D'Elia E, Gasparini S, Guerra S, Harari S, Kraft M, Mennella L, Papi A, Parrella R, Pelosi P, Polverino M, Tana C, Terribile R, Woods JC, Di Marco F, Martinez FD, ItaliCO study group, Ruocco G, Falco G, Poletti V. Comorbidities, Cardiovascular Therapies, and COVID-19 Mortality: A Nationwide, Italian Observational Study (ItaliCO). Front Cardiovasc Med. 2020; 7:585866. PMID: 33195473; PMCID: PMC7583635.
      Citations: 28     
    54. Polverino F, Curtis JL. The ABCs of Granulomatous Lung Diseases: Age-associated B Cells. Am J Respir Crit Care Med. 2020 10 01; 202(7):922-924. PMID: 32603192; PMCID: PMC7528779.
      Citations: 2     Fields:    Translation:HumansCells
    55. Polverino M, Capuozzo A, Cicchitto G, Ferrigno F, Mauro I, Santoriello C, Sirignano E, Aliverti A, Celli B, Polverino F. Smoking Pattern in Men and Women: A Possible Contributor to Sex Differences in Smoke-related Lung Diseases. Am J Respir Crit Care Med. 2020 10 01; 202(7):1048-1051. PMID: 32479109; PMCID: PMC7528782.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    56. Divo MJ, Marin Oto M, Casanova Macario C, Cabrera Lopez C, de-Torres JP, Marin Trigo JM, Hersh CP, Maguire C, Pinto-Plata VM, Polverino F, Ross JC, DeMeo D, Bastarrika G, Silverman EK, Celli BR, Ezponda Casaj?s A. Somatotypes trajectories during adulthood and their association with COPD phenotypes. ERJ Open Res. 2020 Jul; 6(3). PMID: 32963991; PMCID: PMC7487345.
      Citations: 1     
    57. Polverino F. Cigarette Smoking and COVID-19: A Complex Interaction. Am J Respir Crit Care Med. 2020 08 01; 202(3):471-472. PMID: 32530714; PMCID: PMC7397788.
      Citations: 22     Fields:    Translation:HumansCellsPHPublic Health
    58. Polverino F, Balestro E, Spagnolo P. Clinical Presentations, Pathogenesis, and Therapy of Sarcoidosis: State of the Art. J Clin Med. 2020 Jul 24; 9(8). PMID: 32722050; PMCID: PMC7465477.
      Citations: 5     
    59. Kimura H, Francisco D, Conway M, Martinez FD, Vercelli D, Polverino F, Billheimer D, Kraft M. Type 2 inflammation modulates ACE2 and TMPRSS2 in airway epithelial cells. J Allergy Clin Immunol. 2020 Jul; 146(1):80-88.e8. PMID: 32422146; PMCID: PMC7227558.
      Citations: 105     Fields:    Translation:HumansCellsPHPublic Health
    60. Scoppetta C, Di Gennaro G, Polverino F. Editorial - High dose intravenous immunoglobulins as a therapeutic option for COVID-19 patients. Eur Rev Med Pharmacol Sci. 2020 05; 24(9):5178-5179. PMID: 32432784.
      Citations:    
    61. Polverino F, Soriano JB. Small airways and early origins of COPD: pathobiological and epidemiological considerations. Eur Respir J. 2020 03; 55(3). PMID: 32139589.
      Citations:    Fields:    Translation:Humans
    62. Cicchitto G, Polverino M, Capuozzo A, Cacace L, Cavallera A, Mauro I, Ferrigno F, Polverino F. RP EBUS as a guide for transbronchial pulmonary biopsy in the diagnosis of organizing pneumonia. Multidiscip Respir Med. 2020 Jan 28; 15(1):658. PMID: 32782790; PMCID: PMC7385527.
      Citations: 1     
    63. Polverino F, Hysinger EB, Gupta N, Willmering M, Olin T, Abman SH, Woods JC. Lung MRI as a Potential Complementary Diagnostic Tool for Early COPD. Am J Med. 2020 06; 133(6):757-760. PMID: 31954683.
      Citations: 4     Fields:    Translation:Humans
    64. Sullivan JL, Bagevalu B, Glass C, Sholl L, Kraft M, Martinez FD, Bastarrika G, de-Torres JP, San Jose Estepar R, Guerra S, Polverino F. B Cell-Adaptive Immune Profile in Emphysema-Predominant Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2019 12 01; 200(11):1434-1439. PMID: 31348682; PMCID: PMC6884042.
      Citations: 9     Fields:    Translation:HumansCells
    65. Pinto-Plata V, Divo M, Tesfaigzi Y, Calhoun V, Sui J, Polverino F, Priolo C, de Torres JP, Marin JM, Owen CA, Celli B, Casanova C, Petersen H, Baz R, Cordova E. Plasma metabolomics and clinical predictors of survival differences in COPD patients. Respir Res. 2019 Oct 15; 20(1):219. PMID: 31615518; PMCID: PMC6794856.
      Citations: 9     Fields:    Translation:Humans
    66. Esposito R, Spaziano G, Giannattasio D, Ferrigno F, Liparulo A, Rossi A, Roviezzo F, Sessa M, Falciani M, Berrino L, Polverino M, Polverino F, D'Agostino B. Montelukast Improves Symptoms and Lung Function in Asthmatic Women Compared With Men. Front Pharmacol. 2019; 10:1094. PMID: 31611790; PMCID: PMC6769077.
      Citations: 5     
    67. Polverino F, Lu B, Quintero JR, Vargas SO, Patel AS, Owen CA, Gerard NP, Gerard C, Cernadas M. CFTR regulates B cell activation and lymphoid follicle development. Respir Res. 2019 Jul 01; 20(1):133. PMID: 31262295; PMCID: PMC6604167.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    68. Polverino F, Sam A, Guerra S. COPD: To Be or Not to Be, That is the Question. Am J Med. 2019 11; 132(11):1271-1278. PMID: 31152719; PMCID: PMC8359778.
      Citations: 2     Fields:    Translation:Humans
    69. Polverino F. Deconvoluting Chronic Obstructive Pulmonary Disease: Are B Cells the Frontrunners? Am J Respir Crit Care Med. 2019 05 01; 199(9):1170-1171. PMID: 30633537; PMCID: PMC6515871.
      Citations:    Fields:    Translation:HumansCells
    70. Polverino F, Divo M, Cabrera L?pez C, Casanova Macario C, Mar?n Trigo JM, de-Torres JP, Torres RS, Gonz?lez JM, Pinto Plata V, Zulueta J, Callejas FJ, Celli B. Prognostic Validation Using GesEPOC 2017 Severity Criteria. Arch Bronconeumol (Engl Ed). 2019 Aug; 55(8):409-413. PMID: 30718019.
      Citations: 2     Fields:    Translation:Humans
    71. Rojas-Quintero J, Wang X, Tipper J, Burkett PR, Ashtekar AR, Polverino F, Rout A, Yambayev I, Harrod KS, Owen CA, Zu?iga J, Hern?ndez C, Jimenez L, Ram?rez G. Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection. JCI Insight. 2018 12 20; 3(24). PMID: 30568032; PMCID: PMC6338318.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    72. Polverino F, Soriano JB, Cosio BG. What is early COPD and why is it important? Eur Respir J. 2018 12; 52(6). PMID: 30309976.
      Citations: 24     Fields:    Translation:Humans
    73. Petersen H, Sood A, Polverino F, Owen CA, Pinto-Plata V, Tesfaigzi Y, Celli BR. The Course of Lung Function in Middle-aged Heavy Smokers: Incidence and Time to Early Onset of Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 12 01; 198(11):1449-1451. PMID: 30114375; PMCID: PMC6290951.
      Citations: 6     Fields:    Translation:Humans
    74. Polverino F, Rojas-Quintero J, Wang X, Petersen H, Zhang L, Gai X, Higham A, Zhang D, Gupta K, Rout A, Yambayev I, Pinto-Plata V, Sholl LM, Cunoosamy D, Goldring J, Singh D, Tesfaigzi Y, Wedzicha J, Olsson H, Owen CA, Celli BR. A Disintegrin and Metalloproteinase Domain-8: A Novel Protective Proteinase in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2018 11 15; 198(10):1254-1267. PMID: 29750543; PMCID: PMC6290938.
      Citations: 15     Fields:    Translation:HumansAnimals
    75. Roviezzo F, Polverino F, Tartaglione G, Spaziano G, Sgambato M, Russo TP, Liparulo A, Esposito R, Mirra S, Filosa R, D'Agostino B. Nociceptin/Orphanin Fq in inflammation and remodeling of the small airways in experimental model of airway hyperresponsiveness. Physiol Rep. 2018 10; 6(20):e13906. PMID: 30370666; PMCID: PMC6204362.
      Citations: 3     Fields:    Translation:Animals
    76. Patino E, Bhatia D, Rojas-Quintero J, Ma KC, Finkelsztein EJ, Osorio JC, Malick F, Polverino F, Owen CA, Ryter SW, Choi AM, Cloonan SM, Choi ME, Pab?n MA. Beclin-1 regulates cigarette smoke-induced kidney injury in a murine model of chronic obstructive pulmonary disease. JCI Insight. 2018 09 20; 3(18). PMID: 30232271; PMCID: PMC6237223.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    77. De Benedetto F, Pastorelli R, Ferrario M, de Blasio F, Marinari S, Brunelli L, Wouters EFM, Polverino F, Celli BR, Interdisciplinary Association for Research in Lung Disease (AIMAR) Study Group. Supplementation with Qter? and Creatine improves functional performance in COPD patients on long term oxygen therapy. Respir Med. 2018 09; 142:86-93. PMID: 30170808.
      Citations: 9     Fields:    Translation:Humans
    78. Laucho-Contreras ME, Polverino F, Rojas-Quintero J, Wang X, Owen CA. Club cell protein 16 (Cc16) deficiency increases inflamm-aging in the lungs of mice. Physiol Rep. 2018 08; 6(15):e13797. PMID: 30084231; PMCID: PMC6079172.
      Citations: 7     Fields:    Translation:Animals
    79. Wang X, Polverino F, Rojas-Quintero J, Zhang D, Yambayev I, Lindqvist E, Virtala R, Djukanovic R, Davies DE, Wilson S, O'Donnell R, Cunoosamy D, Hazon P, Higham A, Singh D, Olsson H, Owen CA, S?nchez J. A Disintegrin and A Metalloproteinase-9 (ADAM9): A Novel Proteinase Culprit with Multifarious Contributions to COPD. Am J Respir Crit Care Med. 2018 Jun 04. PMID: 29864380; PMCID: PMC6298633.
      Citations: 14     Fields:    
    80. Polverino F, Celli B. The Challenge of Controlling the COPD Epidemic: Unmet Needs. Am J Med. 2018 09; 131(9S):1-6. PMID: 29778456.
      Citations: 8     Fields:    Translation:HumansPHPublic Health
    81. Polverino F, de Torres JP, Santoriello C, Capuozzo A, Mauro I, Rojas-Quintero J, D'Agostino B, Pistolesi M, Celli B, Polverino M, Owen CA. Gas exchange and breathing pattern in women with postmenopausal bone fragility. Respir Med. 2018 04; 137:141-146. PMID: 29605198.
      Citations:    
    82. Divo MJ, Celli BR, Casanova C, Pinto-Plata VM, Cabrera-Lopez C, Polverino F, Poblador-Plou B, Calder?n-Larra?aga A, de-Torres JP, Gimeno-Feliu LA, Bert? J, Zulueta JJ, Carmona P?r?z J, Prados-Torres A, Marin JM, EpiChron?BODE Collaborative Group. Chronic Obstructive Pulmonary Disease (COPD) as a disease of early aging: Evidence from the EpiChron Cohort. PLoS One. 2018; 13(2):e0193143. PMID: 29470502; PMCID: PMC5823454.
      Citations: 22     Fields:    Translation:HumansCTClinical Trials
    83. Polverino F, Divo M, Cabrera L?pez C, Casanova Macario C, Mar?n Trigo JM, de-Torres JP, Sicilia Torres R, Gonz?lez JM, Pinto Plata V, Zulueta JJ, Celli B. Comparison of the 2017 and 2015 Global Initiative for Chronic Obstructive Lung Disease Reports. Impact on Grouping and Outcomes. Am J Respir Crit Care Med. 2018 02 15; 197(4):463-469. PMID: 29099607.
      Citations: 36     Fields:    Translation:Humans
    84. Polverino F, Celli BR, Owen CA. Reply to Voelkel: Cigarette Smoke Is an Endothelial Cell Toxin. Am J Respir Crit Care Med. 2018 01 15; 197(2):274-275. PMID: 28726486; PMCID: PMC5768906.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    85. Polverino F, Celli BR, Owen CA. COPD as an endothelial disorder: endothelial injury linking lesions in the lungs and other organs? (2017 Grover Conference Series). Pulm Circ. 2018 Jan-Mar; 8(1):2045894018758528. PMID: 29468936; PMCID: PMC5826015.
      Citations: 42     
    86. Polverino F, Celli BR, Owen CA. Chronic Obstructive Pulmonary Disease: Breathing New Life into Old Cardiovascular Drugs? Ann Am Thorac Soc. 2017 11; 14(11):1718. PMID: 28950067.
      Citations: 1     Fields:    Translation:Humans
    87. Polverino F. Best of Milan 2017-repair of the emphysematous lung: mesenchymal stromal cell and matrix. J Thorac Dis. 2017 Nov; 9(Suppl 16):S1544-S1547. PMID: 29255637; PMCID: PMC5717365.
      Citations: 1     
    88. Polverino F, Laucho-Contreras ME, Petersen H, Bijol V, Sholl LM, Choi ME, Divo M, Pinto-Plata V, Chetta A, Tesfaigzi Y, Owen CA, Celli BR. A Pilot Study Linking Endothelial Injury in Lungs and Kidneys in Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017 06 01; 195(11):1464-1476. PMID: 28085500; PMCID: PMC5470750.
      Citations: 38     Fields:    Translation:HumansAnimals
    89. Polverino F, Seys LJ, Bracke KR, Owen CA. B cells in chronic obstructive pulmonary disease: moving to center stage. Am J Physiol Lung Cell Mol Physiol. 2016 Oct 01; 311(4):L687-L695. PMID: 27542809; PMCID: PMC5142126.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    90. Jiang Z, Lao T, Qiu W, Polverino F, Gupta K, Guo F, Mancini JD, Naing ZZ, Cho MH, Castaldi PJ, Sun Y, Yu J, Laucho-Contreras ME, Kobzik L, Raby BA, Choi AM, Perrella MA, Owen CA, Silverman EK, Zhou X. A Chronic Obstructive Pulmonary Disease Susceptibility Gene, FAM13A, Regulates Protein Stability of ?-Catenin. Am J Respir Crit Care Med. 2016 07 15; 194(2):185-97. PMID: 26862784; PMCID: PMC5003213.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    91. Schiavo A, Renis M, Polverino M, Iannuzzi A, Polverino F. Acid-base balance, serum electrolytes and need for non-invasive ventilation in patients with hypercapnic acute exacerbation of chronic obstructive pulmonary disease admitted to an internal medicine ward. Multidiscip Respir Med. 2016; 11:23. PMID: 27226896; PMCID: PMC4879756.
      Citations: 2     
    92. Polverino F, Laucho-Contreras M, Rojas Quintero J, Divo M, Pinto-Plata V, Sholl L, de-Torres JP, Celli BR, Owen CA. Increased expression of A Proliferation-inducing Ligand (APRIL) in lung leukocytes and alveolar epithelial cells in COPD patients with non small cell lung cancer: a possible link between COPD and lung cancer? Multidiscip Respir Med. 2016; 11:17. PMID: 27047662; PMCID: PMC4819280.
      Citations: 4     
    93. Cote C, Pinto-Plata V, Divo MJ, Polverino F, Marin JM, Casanova C, Montes de Oca M, de Torres JP, Zulueta J, Cabrera C, Carrizo S, Celli BR, En Representaci?n del Grupo BODE. Simplifying the guidelines: The 10 COPD commandments. Arch Bronconeumol. 2016 Apr; 52(4):179-80. PMID: 26973024.
      Citations: 4     Fields:    Translation:Humans
    94. Laucho-Contreras ME, Polverino F, Tesfaigzi Y, Pilon A, Celli BR, Owen CA. Club Cell Protein 16 (CC16) Augmentation: A Potential Disease-modifying Approach for Chronic Obstructive Pulmonary Disease (COPD). Expert Opin Ther Targets. 2016 Jul; 20(7):869-83. PMID: 26781659; PMCID: PMC4977029.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    95. Cloonan SM, Glass K, Laucho-Contreras ME, Bhashyam AR, Cervo M, Konrad C, Polverino F, Siempos II, Perez E, Mizumura K, Ghosh MC, Parameswaran H, Williams NC, Rooney KT, Chen ZH, Goldklang MP, Yuan GC, Moore SC, Demeo DL, Rouault TA, D'Armiento JM, Schon EA, Manfredi G, Quackenbush J, Mahmood A, Silverman EK, Owen CA, Choi AM, Pab?n MA. Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice. Nat Med. 2016 Feb; 22(2):163-74. PMID: 26752519; PMCID: PMC4742374.
      Citations: 110     Fields:    Translation:HumansAnimalsCells
    96. Polverino F, Longhini F, Vanaudenaerde B, Bikov A, Aamli A, Singanayagam A, Kahn N, Boots A, Skoczynski S. Juniors' voice at the ERS International Congress, Amsterdam 2015: Juniors' voice. Breathe (Sheff). 2015 Dec; 11(4):303-5. PMID: 27066124; PMCID: PMC4818221.
      Citations:    
    97. Polverino F, Cosio BG, Pons J, Laucho-Contreras M, Tejera P, Iglesias A, Rios A, Jahn A, Sauleda J, Divo M, Pinto-Plata V, Sholl L, Rosas IO, Celli BR, Owen CA, Agust? A. B Cell-Activating Factor. An Orchestrator of Lymphoid Follicles in Severe Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2015 Sep 15; 192(6):695-705. PMID: 26073875; PMCID: PMC4595676.
      Citations: 48     Fields:    Translation:HumansCells
    98. Laucho-Contreras ME, Polverino F, Gupta K, Taylor KL, Kelly E, Pinto-Plata V, Divo M, Ashfaq N, Petersen H, Stripp B, Pilon AL, Tesfaigzi Y, Celli BR, Owen CA. Protective role for club cell secretory protein-16 (CC16) in the development of COPD. Eur Respir J. 2015 Jun; 45(6):1544-56. PMID: 25700379; PMCID: PMC4451404.
      Citations: 50     Fields:    Translation:HumansAnimals
    99. Lao T, Glass K, Qiu W, Polverino F, Gupta K, Morrow J, Mancini JD, Vuong L, Perrella MA, Hersh CP, Owen CA, Quackenbush J, Yuan GC, Silverman EK, Zhou X. Haploinsufficiency of Hedgehog interacting protein causes increased emphysema induced by cigarette smoke through network rewiring. Genome Med. 2015; 7(1):12. PMID: 25763110; PMCID: PMC4355149.
      Citations: 28     Fields:    
    100. Polverino F, Doyle-Eisele M, McDonald J, Wilder JA, Royer C, Laucho-Contreras M, Kelly EM, Divo M, Pinto-Plata V, Mauderly J, Celli BR, Tesfaigzi Y, Owen CA. A novel nonhuman primate model of cigarette smoke-induced airway disease. Am J Pathol. 2015 Mar; 185(3):741-55. PMID: 25542772; PMCID: PMC4348468.
      Citations: 22     Fields:    Translation:Animals
    101. Roychaudhuri R, Hergrueter AH, Polverino F, Laucho-Contreras ME, Gupta K, Borregaard N, Owen CA. ADAM9 is a novel product of polymorphonuclear neutrophils: regulation of expression and contributions to extracellular matrix protein degradation during acute lung injury. J Immunol. 2014 Sep 01; 193(5):2469-82. PMID: 25063875; PMCID: PMC4134955.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    102. Matteis M, Polverino F, Spaziano G, Roviezzo F, Santoriello C, Sullo N, Bucci MR, Rossi F, Polverino M, Owen CA, D'Agostino B. Effects of sex hormones on bronchial reactivity during the menstrual cycle. BMC Pulm Med. 2014 Jul 01; 14:108. PMID: 24984749; PMCID: PMC4106209.
      Citations: 18     Fields:    Translation:Humans
    103. Cicchitto G, Musella V, Acitorio M, Capuano N, Fiorenzano G, Owen CA, Polverino M, Polverino F. Idiopathic pulmonary fibrosis and coronary artery disease. Multidiscip Respir Med. 2014; 9(1):31. PMID: 24976970; PMCID: PMC4074111.
      Citations: 2     
    104. Craig VJ, Polverino F, Laucho-Contreras ME, Shi Y, Liu Y, Osorio JC, Tesfaigzi Y, Pinto-Plata V, Gochuico BR, Rosas IO, Owen CA. Mononuclear phagocytes and airway epithelial cells: novel sources of matrix metalloproteinase-8 (MMP-8) in patients with idiopathic pulmonary fibrosis. PLoS One. 2014; 9(5):e97485. PMID: 24828408; PMCID: PMC4020836.
      Citations: 19     Fields:    Translation:HumansCells
    105. Polverino F, Santoriello C, Girbino G, Cappetta D, D'Agostino B, Vatrella A, Polverino M, Milic-Emili J, And? F. Recumbent deoxygenation in mild/moderate liver cirrhosis: the "clinodeoxia". The ortho-clino paradigm. Respir Med. 2014 Jul; 108(7):1040-8. PMID: 24785153.
      Citations:    Fields:    Translation:Humans
    106. Iannuzzi A, Licenziati MR, De Michele F, Verga MC, Santoriello C, Di Buono L, Renis M, Lembo L, D'Agostino B, Cappetta D, Polverino M, Polverino F. C-reactive protein and carotid intima-media thickness in children with sleep disordered breathing. J Clin Sleep Med. 2013 May 15; 9(5):493-8. PMID: 23674941; PMCID: PMC3629324.
      Citations: 7     Fields:    Translation:Humans
    107. Knolle MD, Nakajima T, Hergrueter A, Gupta K, Polverino F, Craig VJ, Fyfe SE, Zahid M, Permaul P, Cernadas M, Montano G, Tesfaigzi Y, Sholl L, Kobzik L, Israel E, Owen CA. Adam8 limits the development of allergic airway inflammation in mice. J Immunol. 2013 Jun 15; 190(12):6434-49. PMID: 23670189; PMCID: PMC3679335.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    108. Polverino F, Ricciardi M, Polverino M, Santoriello C, Palladino R, Pistolesi M. Voice box symptoms: a hitherto unknown presentation of pulmonary embolism. Am J Respir Crit Care Med. 2013 Jan 01; 187(1):108-10. PMID: 23281354.
      Citations: 1     Fields:    Translation:Humans
    109. Sullo N, Roviezzo F, Matteis M, Spaziano G, Del Gaudio S, Lombardi A, Lucattelli M, Polverino F, Lungarella G, Cirino G, Rossi F, D'Agostino B. Skeletal muscle oxidative metabolism in an animal model of pulmonary emphysema: formoterol and skeletal muscle dysfunction. Am J Respir Cell Mol Biol. 2013 Feb; 48(2):198-203. PMID: 23144332.
      Citations: 3     Fields:    Translation:AnimalsCells
    110. Polverino M, Polverino F, Fasolino M, Alfieri A, De Blasio F, And? F. Anatomy and neuro-pathophysiology of the cough reflex arc. Multidiscip Respir Med. 2012 Jun 18; 7(1):5. PMID: 22958367; PMCID: PMC3415124.
      Citations: 27     
    111. Cuomo G, Santoriello C, Polverino F, Ruocco L, Valentini G, Polverino M. Impaired exercise performance in systemic sclerosis and its clinical correlations. Scand J Rheumatol. 2010 Aug; 39(4):330-5. PMID: 20476863.
      Citations:    
    112. Polverino F, Baraldo S, Bazzan E, Agostini S, Turato G, Lunardi F, Balestro E, Damin M, Papi A, Maestrelli P, Calabrese F, Saetta M. A novel insight into adaptive immunity in chronic obstructive pulmonary disease: B cell activating factor belonging to the tumor necrosis factor family. Am J Respir Crit Care Med. 2010 Oct 15; 182(8):1011-9. PMID: 20581172.
      Citations: 25     Fields:    Translation:HumansCells
    113. Polverino M, Cirino G, Lombardi A, Grassi B, Sullo N, Santoriello C, Polverino F, Orlotti D, Matteis M, Rossi F, D'Agostino B. Exercise capacity and cytochrome oxidase activity in muscle mitochondria of COPD patients. Respir Med. 2010 Jan; 104(1):83-90. PMID: 19716278.
      Citations: 4     Fields:    Translation:HumansCells
    114. Polverino F, Santoriello C, De Sio V, de Blasio F, Polverino M, And? F. Sexual intercourse and respiratory failure. Respir Med. 2008 Jun; 102(6):927-31. PMID: 18394872.
      Citations:    Fields:    Translation:Humans
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