Joshua Anthony Keefe

TitleGraduate Student
InstitutionBaylor College of Medicine
DepartmentDevelopment, Disease Models & Therapeutics
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Keefe JA, Zhao S, Wehrens XHT. A mechanistic LNK between inflammation and atrial fibrillation? Cardiovasc Res. 2024 Jul 02; 120(8):814-816. PMID: 38713542; PMCID: PMC11218683.
      Citations:    Fields:    
    2. Keefe JA, Garber R, McCauley MD, Wehrens XHT. Tachycardia and Atrial Fibrillation-Related Cardiomyopathies: Potential Mechanisms and Current Therapies. JACC Heart Fail. 2024 Apr; 12(4):605-615. PMID: 38206235.
      Citations:    Fields:    
    3. Moore OM, Aguilar-Sanchez Y, Lahiri SK, Hulsurkar MM, Alberto Navarro-Garcia J, Word TA, Keefe JA, Barazi D, Munivez EM, Moore CT, Parthasarathy V, Davidson J, Lagor WR, Park SH, Bao G, Miyake CY, Wehrens XHT. Long-term efficacy and safety of cardiac genome editing for catecholaminergic polymorphic ventricular tachycardia. J Cardiovasc Aging. 2024 Jan; 4(1). PMID: 38464671; PMCID: PMC10919902.
    4. Moore OM, Keefe JA, Wehrens XHT. Endothelial cell dysfunction: the culprit for cardiac denervation in aging? J Cardiovasc Aging. 2023 Oct; 3(4). PMID: 38235058; PMCID: PMC10793999.
    5. Song J, Navarro-Garcia JA, Wu J, Saljic A, Abu-Taha I, Li L, Lahiri SK, Keefe JA, Aguilar-Sanchez Y, Moore OM, Yuan Y, Wang X, Kamler M, Mitch WE, Ruiz-Hurtado G, Hu Z, Thomas SS, Dobrev D, Wehrens XH, Li N. Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation. J Clin Invest. 2023 10 02; 133(19). PMID: 37581942; PMCID: PMC10541185.
      Citations: 2     Fields:    Translation:HumansAnimals
    6. Keefe JA, Wehrens XHT. Anti-Ro/SSA Antibodies in?Atrioventricular Block: Innocent Bystander or Mechanistic Driver? JACC Clin Electrophysiol. 2023 08; 9(8 Pt 3):1649-1651. PMID: 37354190.
      Citations:    Fields:    Translation:Humans
    7. Sy MR, Keefe JA, Sutton JP, Wehrens XHT. Cardiac function, structural, and electrical remodeling by microgravity exposure. Am J Physiol Heart Circ Physiol. 2023 01 01; 324(1):H1-H13. PMID: 36399385; PMCID: PMC9762974.
      Citations: 2     Fields:    Translation:Humans
    8. Keefe JA, Avadhanula V, Nicholson EG, Devaraj S, Piedra PA, Bozkurt B, Wehrens XHT. Abnormalities in cardiac and inflammatory biomarkers in ambulatory subjects after COVID-19 infection. Int J Cardiol Heart Vasc. 2022 Dec; 43:101144. PMID: 36321063; PMCID: PMC9613792.
      Citations: 1     
    9. Keefe JA, Moore OM, Ho KS, Wehrens XHT. Role of Ca2+ in healthy and pathologic cardiac function: from normal excitation-contraction coupling to mutations that cause inherited arrhythmia. Arch Toxicol. 2023 01; 97(1):73-92. PMID: 36214829; PMCID: PMC10122835.
      Citations: 1     Fields:    Translation:HumansCells
    10. Keefe JA, Hulsurkar MM, Reilly S, Wehrens XHT. Mouse models of spontaneous atrial fibrillation. Mamm Genome. 2023 Jun; 34(2):298-311. PMID: 36173465; PMCID: PMC10898345.
      Citations: 1     Fields:    Translation:Animals
    11. Keefe JA, Wehrens XHT, Dobrev D. Common disease-promoting signalling pathways in heart failure and atrial fibrillation: putative underlying mechanisms and potential therapeutic consequences. Cardiovasc Res. 2022 08 24; 118(11):2397-2399. PMID: 35788838.
      Citations:    Fields:    
    12. Keefe JA, Navarro-Garcia JA, Ni L, Reilly S, Dobrev D, Wehrens XHT. In-depth characterization of a mouse model of postoperative atrial fibrillation. J Cardiovasc Aging. 2022; 2. PMID: 36337729; PMCID: PMC9632544.
      Citations: 2     
    13. Ho KS, Keefe JA, Wehrens XHT. Diagnosing atrial fibrillation: Can we do better than the ECG? Heart Rhythm. 2022 09; 19(9):1459-1460. PMID: 35697327; PMCID: PMC10077874.
      Citations:    Fields:    
    14. Keefe J, Yao C, Hwang SJ, Courchesne P, Lee GY, Mizgerd JP, O'Connor G, Washko GR, Cho MH, Silverman EK, Levy D, Dupuis J. An Integrative Genomic Strategy Identifies sRAGE as a Causal and Protective Biomarker of Lung Function. Chest. 2022 01; 161(1):76-84. PMID: 34237330; PMCID: PMC8783029.
      Citations: 1     Fields:    Translation:Humans
    15. Lee DH, Yao C, Bhan A, Schlaeger T, Keefe J, Rodriguez BAT, Hwang SJ, Chen MH, Levy D, Johnson AD. Integrative Genomic Analysis Reveals Four Protein Biomarkers for Platelet Traits. Circ Res. 2020 10 09; 127(9):1182-1194. PMID: 32781905; PMCID: PMC8411925.
      Citations: 5     Fields:    Translation:HumansCells
    16. Yin X, Willinger CM, Keefe J, Liu J, Adourian A, Chen G, Pamplona R, Portero-Otin M, Jove M, Courchesne P, van Duijn CM, Demirkan A, Larson MG, Levy D, Fern?ndez-Ortiz A, Ib??ez B, Pe?alvo J, Corella D, Fuster V, Ordov?s JM. Lipidomic profiling identifies signatures of metabolic risk. EBioMedicine. 2020 Jan; 51:102520. PMID: 31877415; PMCID: PMC6938899.
      Citations: 19     Fields:    Translation:HumansAnimals
    17. Huan T, Joehanes R, Song C, Peng F, Guo Y, Mendelson M, Yao C, Liu C, Ma J, Richard M, Agha G, Guan W, Almli LM, Conneely KN, Keefe J, Hwang SJ, Johnson AD, Fornage M, Liang L, Levy D. Genome-wide identification of DNA methylation QTLs in whole blood highlights pathways for cardiovascular disease. Nat Commun. 2019 09 19; 10(1):4267. PMID: 31537805; PMCID: PMC6753136.
      Citations: 56     Fields:    Translation:HumansCells
    18. Huan T, Mendelson M, Joehanes R, Yao C, Liu C, Song C, Bhattacharya A, Rong J, Tanriverdi K, Keefe J, Murabito JM, Courchesne P, Larson MG, Freedman JE, Levy D. Epigenome-wide association study of DNA methylation and microRNA expression highlights novel pathways for human complex traits. Epigenetics. 2020 Jan - Feb; 15(1-2):183-198. PMID: 31282290; PMCID: PMC6961684.
      Citations: 3     Fields:    Translation:HumansCells
    19. Keefe JA, Hwang SJ, Huan T, Mendelson M, Yao C, Courchesne P, Saleh MA, Madhur MS, Levy D. Evidence for a Causal Role of the SH2B3-?2M Axis in Blood Pressure Regulation. Hypertension. 2019 02; 73(2):497-503. PMID: 30624993; PMCID: PMC6334659.
      Citations: 2     Fields:    Translation:HumansAnimals
    20. Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D, Laser A, Gieger C. Author Correction: Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 09 18; 9(1):3853. PMID: 30228274; PMCID: PMC6143533.
      Citations: 3     Fields:    
    21. Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D, Laser A, Gieger C. Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease. Nat Commun. 2018 08 15; 9(1):3268. PMID: 30111768; PMCID: PMC6093935.
      Citations: 79     Fields:    Translation:HumansCells
    22. Lee CK, de Anda J, Baker AE, Bennett RR, Luo Y, Lee EY, Keefe JA, Helali JS, Ma J, Zhao K, Golestanian R, O'Toole GA, Wong GCL. Multigenerational memory and adaptive adhesion in early bacterial biofilm communities. Proc Natl Acad Sci U S A. 2018 04 24; 115(17):4471-4476. PMID: 29559526; PMCID: PMC5924909.
      Citations: 46     Fields:    Translation:Cells
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