TitleSenior Faculty
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
Houston, TX 77030
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    Collapse Biography 
    Collapse education and training
    University of Florida, Gainesville, FLBS05/1995Biochemistry and Molecular Biology
    Duke University, Durham, NCMD05/1999Medicine
    University of Michigan, Ann Arbor, MIResidency06/2003Internal Medicine/Pediatrics
    National Institutes of Health, Bethesda, MDFellowship10/2007Adult Critical Care Medicine
    Johns Hopkins Hospital, Baltimore, MDFellowship06/2008Pediatric Critical Care Medicine
    Collapse awards and honors
    1994 - 1995Florida Blue Key Leadership Honorary, University of Florida
    1994 - 1995Phi Beta Kappa, University of Florida
    2000Token of Appreciation (medical school teaching), University of Michigan
    2003Internal Medicine Top Research Project , University of Michigan
    2007Fellowship Abstract Research Award, NIH Intramural
    2007Top Abstract, Nitrite International Conference
    2007Young Investigator Award, American Heart Association
    2007Best Research Presentation, Anesthesia and Critical Care, Johns Hopkins Hospital
    2010 - 2014Attending of the Year finalist (3/4 years), University of Miami and University of Pittsburgh
    2015Faculty of 1000
    2015Top Abstract Award, Nitric Oxide Gordon Research Conference
    2018Pitt Innovation Challenge Winner, University of Pittsburgh
    2018Fellow of the American Heart Association
    2020Pediatric Critical Care Medicine Faculty of the Year, University of Pittsburgh

    Collapse Overview 
    Collapse overview
    I am a translational researcher investigating therapies aimed at providing cardioprotection and neuroprotection after global ischemia and reperfusion as seen with cardiac arrest and cardiac surgery.

    Collapse Research 
    Collapse research activities and funding
         (Dezfulian, Cameron)Oct 1, 2016 - Aug 4, 2020
    Mallinckrodt Pharmaceuticals, Inc.
    Inhaled Nitric Oxide after Out-of-hospital Cardiac Arrest
    Role Description: RCT of inhaled nitric oxide vs placebo in out-of-hospital cardiac arrest patients
    Role: PI

    R01HL129722     (KIM, FRANCIS)Jul 1, 2016 - Apr 30, 2021
    Randomized clinical trial of sodium nitrite for out of hospital cardiac arrest
    Role: Co-Investigator

    15UFEL23750003 and 17UFEL23750003     (Dezfulian, Cameron)Feb 15, 2015 - Jan 31, 2020
    American Heart Association
    Undergraduate Student Research Program
    Role Description: Director of a summer research program for undergraduates.
    Role: PI/ PD

    R21AR066305     (DOMSIC, ROBYN THERESE)Feb 1, 2015 - Jan 31, 2019
    Effect of Atorvastatin on Endothelial Function and Raynaud in Diffuse Scleroderma
    Role: Co-Investigator

         (Dezfulian, Cameron)Aug 1, 2013 - Oct 1, 2014
    Laerdal Foundation
    Nitrite and nitric oxide modulation of cerebral blood flow
    Role Description: Examine the impact of nitrite therapy on cerebral blood pressure autoregulation
    Role: PI

    K08NS069817     (DEZFULIAN, CAMERON)Sep 15, 2010 - Feb 29, 2016
    Nitrite based neuroprotection after cardiac arrest
    Role: Principal Investigator

    10KN-04     (Dezfulian)Jul 1, 2010 - Feb 2, 2011
    State of Florida/James and Esther King Biomedical Research Program
    Nitrite based neuroprotection after cardiac arrest
    Role Description: Investigate the ability of nitrite to protect brain after cardiac arrest
    Role: PI

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Orkin AM, Dezfulian C, Orkin AM. Recognizing the fastest growing cause of out-of-hospital cardiac arrest. Resuscitation. 2024 May; 198:110206. PMID: 38604441.
      Citations:    Fields:    Translation:Humans
    2. Coppler PJ, Gagnon DJ, Flickinger KL, Elmer J, Callaway CW, Guyette FX, Doshi A, Steinberg A, Dezfulian C, Moskowitz AL, Donnino M, May TL, Seder DB, Rittenberger JC, Coppler PJ, Gagnon DJ, Flickinger KL, Elmer J, Callaway CW, Guyette FX, Doshi A, Steinberg A, Dezfulian C, Moskowitz AL, Donnino M, May TL, Seder DB, Rittenberger JC. A multicenter, randomized, doubleblind, placebo-controlled trial of amantadine to stimulate awakening in comatose patients resuscitated from cardiac arrest. Clin Exp Emerg Med. 2024 Jun; 11(2):205-212. PMID: 38286499; PMCID: PMC11237252.
    3. Bronicki RA, Tume S, Gomez H, Dezfulian C, Penny DJ, Pinsky MR, Burkhoff D. Application of Cardiovascular Physiology to the Critically Ill Patient. Crit Care Med. 2024 05 01; 52(5):821-832. PMID: 38126845.
      Citations:    Fields:    
    4. Flickinger KL, Weissman A, Elmer J, Coppler PJ, Guyette FX, Repine MJ, Dezfulian C, Hopkins D, Frisch A, Doshi AA, Rittenberger JC, Callaway CW. Metabolic Manipulation and Therapeutic Hypothermia. Ther Hypothermia Temp Manag. 2024 Mar; 14(1):46-51. PMID: 37405749.
      Citations:    Fields:    Translation:Humans
    5. Jackson TC, Dezfulian C, Vagni VA, Stezoski J, Janesko-Feldman K, Kochanek PM. PHLPP Inhibitor NSC74429 Is Neuroprotective in Rodent Models of Cardiac Arrest and Traumatic Brain Injury. Biomolecules. 2022 09 23; 12(10). PMID: 36291561; PMCID: PMC9599532.
      Citations:    Fields:    Translation:Animals
    6. Dezfulian C. Understanding heterogeneity in mitochondrial injury after cardiac arrest using plasma metabolomics. Resuscitation. 2022 10; 179:83-85. PMID: 35944816.
    7. Rutledge CA, Kaufman BA, Dezfulian C, Elmer J. Metformin protects against cardiac and renal damage in diabetic cardiac arrest patients. Resuscitation. 2022 05; 174:42-46. PMID: 35331801; PMCID: PMC9050929.
      Citations:    Fields:    Translation:Humans
    8. Rittenberger JC, Weissman A, Flickinger KL, Guyette FX, Hopkins D, Repine MJ, Dezfulian C, Doshi AA, Elmer J, Sawyer KN, Callaway CW. Glycopyrrolate does not ameliorate hypothermia associated bradycardia in healthy individuals: A randomized crossover trial. Resuscitation. 2021 07; 164:79-83. PMID: 34087418; PMCID: PMC8259805.
      Citations:    Fields:    Translation:Humans
    9. Dezfulian C, Orkin AM, Maron BA, Elmer J, Girotra S, Gladwin MT, Merchant RM, Panchal AR, Perman SM, Starks MA, van Diepen S, Lavonas EJ, American Heart Association Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitatio. Opioid-Associated Out-of-Hospital Cardiac Arrest: Distinctive Clinical Features and Implications for Health Care and Public Responses: A Scientific Statement From the American Heart Association. Circulation. 2021 04 20; 143(16):e836-e870. PMID: 33682423.
      Citations: 4     Fields:    Translation:Humans
    10. Uray T, Dezfulian C, Palmer AA, Miner KM, Leak RK, Stezoski JP, Janesko-Feldman K, Kochanek PM, Drabek T. Cardiac Arrest Induced by Asphyxia Versus Ventricular Fibrillation Elicits Comparable Early Changes in Cytokine Levels in the Rat Brain, Heart, and Serum. J Am Heart Assoc. 2021 02; 10(5):e018657. PMID: 33599149; PMCID: PMC8174297.
      Citations: 4     Fields:    Translation:Animals
    11. Dhanani S, Hornby L, van Beinum A, Scales NB, Hogue M, Baker A, Beed S, Boyd JG, Chandler JA, D'Aragon F, Dezfulian C, Doig CJ, Duska F, Friedrich JO, Gardiner D, Gofton T, Harvey D, Herry C, Isac G, Kramer AH, Kutsogiannis DJ, Maslove DM, Meade M, Mehta S, Munshi L, Norton L, Pagliarello G, Ramsay T, Rusinova K, Scales D, Schmidt M, Seely A, Shahin J, Slessarev M, So D, Talbot H, van Mook WNKA, Waldauf P, Weiss M, Wind JT, Shemie SD, Canadian Critical Care Trials Group, Canadian Donation and Transplantation Research Program, Chass? M. Resumption of Cardiac Activity after Withdrawal of Life-Sustaining Measures. N Engl J Med. 2021 01 28; 384(4):345-352. PMID: 33503343.
      Citations: 7     Fields:    Translation:Humans
    12. Kim F, Maynard C, Dezfulian C, Sayre M, Kudenchuk P, Rea T, Sampson D, Olsufka M, May S, Nichol G. Effect of Out-of-Hospital Sodium Nitrite on Survival to Hospital Admission After Cardiac Arrest: A Randomized Clinical Trial. JAMA. 2021 01 12; 325(2):138-145. PMID: 33433575; PMCID: PMC7804921.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    13. Tabi M, Burstein BJ, Ahmed A, Dezfulian C, Kashani KB, Jentzer JC. Shock Severity and Hospital Mortality In Out of Hospital Cardiac Arrest Patients Treated With Targeted Temperature Management. Shock. 2021 01 01; 55(1):48-54. PMID: 32769819.
      Citations:    Fields:    Translation:Humans
    14. Rutledge CA, Chiba T, Redding K, Dezfulian C, Sims-Lucas S, Kaufman BA. A novel ultrasound-guided mouse model of sudden cardiac arrest. PLoS One. 2020; 15(12):e0237292. PMID: 33275630; PMCID: PMC7717537.
      Citations: 3     Fields:    Translation:Animals
    15. Dezfulian C, Lavonas EJ. Precision Cardiac Arrest Resuscitation Based on Etiology. Crit Care Clin. 2020 Oct; 36(4):737-752. PMID: 32892826.
      Citations:    Fields:    Translation:HumansAnimals
    16. Lavonas EJ, Dezfulian C. Impact of the Opioid Epidemic. Crit Care Clin. 2020 Oct; 36(4):753-769. PMID: 32892827.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    17. Kaselitz TB, Dezfulian C, Remy KE. The authors reply. Pediatr Crit Care Med. 2020 10; 21(10):930-931. PMID: 32769699; PMCID: PMC7437422.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    18. Baird A, Coppler PJ, Callaway CW, Dezfulian C, Flickinger KL, Elmer J, University of Pittsburgh Post-Cardiac Arrest Service. Rate of intra-arrest epinephrine administration and early post-arrest organ failure after in-hospital cardiac arrest. Resuscitation. 2020 11; 156:15-18. PMID: 32853724; PMCID: PMC7606719.
      Citations: 1     Fields:    Translation:Humans
    19. Callaway CW, Coppler PJ, Faro J, Puyana JS, Solanki P, Dezfulian C, Doshi AA, Elmer J, Frisch A, Guyette FX, Okubo M, Rittenberger JC, Weissman A. Association of Initial Illness Severity and Outcomes After Cardiac Arrest With Targeted Temperature Management at 36 ?C or 33 ?C. JAMA Netw Open. 2020 07 01; 3(7):e208215. PMID: 32701158; PMCID: PMC7378753.
      Citations: 9     Fields:    Translation:Humans
    20. Remy KE, Verhoef PA, Malone JR, Ruppe MD, Kaselitz TB, Lodeserto F, Hirshberg EL, Slonim A, Dezfulian C. Caring for Critically Ill Adults With Coronavirus Disease 2019 in a PICU: Recommendations by Dual Trained Intensivists. Pediatr Crit Care Med. 2020 07; 21(7):607-619. PMID: 32420720; PMCID: PMC7331597.
      Citations: 12     Fields:    Translation:HumansCellsPHPublic Health
    21. Steinberg A, Callaway C, Dezfulian C, Elmer J. Are providers overconfident in predicting outcome after cardiac arrest? Resuscitation. 2020 08; 153:97-104. PMID: 32544415; PMCID: PMC7390696.
      Citations: 3     Fields:    Translation:Humans
    22. Alcamo AM, Lavezoli R, Dezfulian C, Simon DW, Aneja RK, Clark RSB, Kochanek PM, Fink EL. Feasibility and Performance of a Gel-Adhesive Pad System for Pediatric Targeted Temperature Management: An Exploratory Analysis of 19 Pediatric Critically Ill Patients. Ther Hypothermia Temp Manag. 2021 Mar; 11(1):19-27. PMID: 32429750; PMCID: PMC7910414.
      Citations:    Fields:    Translation:Humans
    23. Dezfulian C. A New Perspective on Pulmonary Hypertension, Right Ventricular Failure, and Pediatric In-Hospital Cardiac Arrest. Pediatr Crit Care Med. 2020 04; 21(4):389-390. PMID: 32251184.
      Citations:    Fields:    Translation:Humans
    24. Vitturi DA, Maynard C, Olsufka M, Straub AC, Krehel N, Kudenchuk PJ, Nichol G, Sayre M, Kim F, Dezfulian C. Nitrite elicits divergent NO-dependent signaling that associates with outcome in out of hospital cardiac arrest. Redox Biol. 2020 05; 32:101463. PMID: 32087553; PMCID: PMC7033352.
      Citations: 4     Fields:    Translation:HumansCells
    25. Ramgopal S, Dezfulian C, Hickey RW, Au AK, Venkataraman S, Clark RSB, Horvat CM. Early Hyperoxemia and Outcome Among Critically Ill Children. Pediatr Crit Care Med. 2020 02; 21(2):e129-e132. PMID: 31821205; PMCID: PMC7304556.
      Citations: 4     Fields:    Translation:Humans
    26. Piao L, Fang YH, Hamanaka RB, Dezfulian C, Archer SL, Sharp WW, Mutlu GM. Suppression of Superoxide-Hydrogen Peroxide Production at Site IQ of Mitochondrial Complex I Attenuates Myocardial Stunning and Improves Postcardiac Arrest Outcomes. Crit Care Med. 2020 02; 48(2):e133-e140. PMID: 31939812; PMCID: PMC6964871.
      Citations: 8     Fields:    Translation:AnimalsCells
    27. Coppler PJ, Dezfulian C. The quest continues to identify coronary occlusion in OHCA without ST elevation. Resuscitation. 2020 01 01; 146:258-260. PMID: 31682899.
      Citations: 1     Fields:    Translation:Humans
    28. Uray T, Empey PE, Drabek T, Stezoski JP, Janesko-Feldman K, Jackson T, Garman RH, Kim F, Kochanek PM, Dezfulian C. Nitrite pharmacokinetics, safety and efficacy after experimental ventricular fibrillation cardiac arrest. Nitric Oxide. 2019 12 01; 93:71-77. PMID: 31526855; PMCID: PMC6957908.
      Citations: 2     Fields:    Translation:HumansAnimals
    29. Ramgopal S, Dezfulian C, Hickey RW, Au AK, Venkataraman S, Clark RSB, Horvat CM. Association of Severe Hyperoxemia Events and Mortality Among Patients Admitted to a Pediatric Intensive Care Unit. JAMA Netw Open. 2019 08 02; 2(8):e199812. PMID: 31433484; PMCID: PMC6707098.
      Citations: 9     Fields:    Translation:Humans
    30. Chonde M, Flickinger KL, Sundermann ML, Koller AC, Salcido DD, Dezfulian C, Menegazzi JJ, Elmer J. Intra-Arrest Administration of Cyclosporine and Methylprednisolone Does Not Reduce Postarrest Myocardial Dysfunction. Biomed Res Int. 2019; 2019:6539050. PMID: 31309111; PMCID: PMC6594305.
      Citations: 3     Fields:    Translation:Animals
    31. Anthonymuthu TS, Kenny EM, Lamade AM, Gidwani H, Krehel NM, Misse A, Gao X, Amoscato AA, Straub AC, Kagan VE, Dezfulian C, Bayir H. Lipidomics Detection of Brain Cardiolipins in Plasma Is Associated With Outcome After Cardiac Arrest. Crit Care Med. 2019 04; 47(4):e292-e300. PMID: 30855329; PMCID: PMC6622168.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    32. Rittenberger JC, Weissman A, Baldwin M, Flickinger K, Repine MJ, Guyette FX, Doshi AA, Dezfulian C, Callaway CW, Elmer J, Pittsburgh Post Cardiac Arrest Service. Preliminary experience with point-of-care EEG in post-cardiac arrest patients. Resuscitation. 2019 02; 135:98-102. PMID: 30605711; PMCID: PMC7155922.
      Citations: 2     Fields:    Translation:Humans
    33. Faro J, Coppler PJ, Dezfulian C, Baldwin M, Molyneaux BJ, Urban A, Rittenberger JC, Callaway CW, Elmer J, Pittsburgh Post-Cardiac Arrest Service. Differential association of subtypes of epileptiform activity with outcome after cardiac arrest. Resuscitation. 2019 03; 136:138-145. PMID: 30586605; PMCID: PMC6397672.
      Citations: 4     Fields:    Translation:Humans
    34. Hirzallah MI, Dezfulian C. The elusive goal carbon dioxide target after cardiac arrest. Resuscitation. 2019 02; 135:226-227. PMID: 30562592.
      Citations:    Fields:    Translation:Humans
    35. Chen N, Callaway CW, Guyette FX, Rittenberger JC, Doshi AA, Dezfulian C, Elmer J, Pittsburgh Post-Cardiac Arrest Service. Arrest etiology among patients resuscitated from cardiac arrest. Resuscitation. 2018 09; 130:33-40. PMID: 29940296; PMCID: PMC6092216.
      Citations: 25     Fields:    Translation:Humans
    36. Kim F, Dezfulian C, Empey PE, Morrell M, Olsufka M, Scruggs S, Kudenchuk P, May S, Maynard C, Sayre MR, Nichol G. Usefulness of Intravenous Sodium Nitrite During Resuscitation for the Treatment of Out-of-Hospital Cardiac Arrest. Am J Cardiol. 2018 08 15; 122(4):554-559. PMID: 30205886; PMCID: PMC6515919.
      Citations: 5     Fields:    Translation:Humans
    37. Uray T, Lamade A, Elmer J, Drabek T, Stezoski JP, Janesko-Feldman K, Garman RH, Chen N, Kochanek PM, Dezfulian C, Callaway CW, Doshi AA, Frisch A, Guyette FX, Reynolds JC, Rittenberger JC, University of Pittsburgh Post-Cardiac Arrest Service, Miss? A. Phenotyping Cardiac Arrest: Bench and Bedside Characterization of Brain and Heart Injury Based on Etiology. Crit Care Med. 2018 06; 46(6):e508-e515. PMID: 29533310; PMCID: PMC5953808.
      Citations: 13     Fields:    Translation:HumansAnimals
    38. Agarwal S, Spiekerkoetter E, Austin ED, de Jesus Perez V, Dezfulian C, Maron BA, Ryan JJ, Starks MA, Yu PB, Bonnet S, Perman SM. Career Development of Young Physician-Scientists in the Cardiovascular Sciences: Perspective and Advice From the Early Career Committee of the Cardiopulmonary, Critical Care, and Resuscitation Council of the American Heart Association. Circ Res. 2018 05 11; 122(10):1330-1333. PMID: 29748361; PMCID: PMC5972553.
      Citations: 4     Fields:    Translation:Humans
    39. Dezfulian C, Fink EL. How Bad Is It to Fail at Pushing Hard and Fast in Pediatric Cardiopulmonary Resuscitation? Pediatr Crit Care Med. 2018 05; 19(5):495-496. PMID: 29727420; PMCID: PMC5940004.
      Citations:    Fields:    Translation:Humans
    40. Elmer J, Flickinger KL, Anderson MW, Koller AC, Sundermann ML, Dezfulian C, Okonkwo DO, Shutter LA, Salcido DD, Callaway CW, Menegazzi JJ. Effect of neuromonitor-guided titrated care on brain tissue hypoxia after opioid overdose cardiac arrest. Resuscitation. 2018 08; 129:121-126. PMID: 29679696; PMCID: PMC6054552.
      Citations: 4     Fields:    Translation:Animals
    41. Wallace DJ, Coppler P, Callaway C, Rittenberger JC, Dezfulian C, Mohan D, Toma C, Elmer J. Selection bias, interventions and outcomes for survivors of cardiac arrest. Heart. 2018 08; 104(16):1356-1361. PMID: 29463613; PMCID: PMC6063756.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    42. Vallentin MF, Secher N, Hansen FB, Dezfulian C, Granfeldt A, Andersen LW, Fabian-Jessing BK. Animal models of cardiac arrest: A systematic review of bias and reporting. Resuscitation. 2018 Apr; 125:16-21. PMID: 29407206.
      Citations: 8     Fields:    Translation:HumansAnimals
    43. Sonder P, Janssens GN, Beishuizen A, Henry CL, Rittenberger JC, Callaway CW, Dezfulian C, Polderman KH. Efficacy of different cooling technologies for therapeutic temperature management: A prospective intervention study. Resuscitation. 2018 03; 124:14-20. PMID: 29288014.
      Citations: 13     Fields:    Translation:Humans
    44. Jentzer JC, Scutella M, Pike F, Fitzgibbon J, Krehel NM, Kowalski L, Callaway CW, Rittenberger JC, Reynolds JC, Barsness GW, Dezfulian C. Early coronary angiography and percutaneous coronary intervention are associated with improved outcomes after out of hospital cardiac arrest. Resuscitation. 2018 02; 123:15-21. PMID: 29223601.
      Citations: 15     Fields:    Translation:Humans
    45. Coppler PJ, Dezfulian C, Elmer J, Rittenberger JC. Temperature management for out-of-hospital cardiac arrest. JAAPA. 2017 Dec; 30(12):30-36. PMID: 29210906; PMCID: PMC7066452.
      Citations:    Fields:    Translation:Humans
    46. Dezfulian C, Olsufka M, Fly D, Scruggs S, Do R, Maynard C, Nichol G, Kim F. Hemodynamic effects of IV sodium nitrite in hospitalized comatose survivors of out of hospital cardiac arrest. Resuscitation. 2018 01; 122:106-112. PMID: 29175357; PMCID: PMC5774860.
      Citations: 6     Fields:    Translation:Humans
    47. Idris AH, Bierens JJLM, Perkins GD, Wenzel V, Nadkarni V, Morley P, Warner DS, Topjian A, Venema AM, Branche CM, Szpilman D, Morizot-Leite L, Nitta M, Webber J, Beerman SB, Youn CS, Jost U, Quan L, Dezfulian C, Handley AJ, Hazinski MF, L?fgren B, Gr?sner JT. 2015 revised Utstein-style recommended guidelines for uniform reporting of data from drowning-related resuscitation: An ILCOR advisory statement. Resuscitation. 2017 09; 118:147-158. PMID: 28728893.
      Citations: 13     Fields:    Translation:Humans
    48. Idris AH, Bierens JJLM, Perkins GD, Wenzel V, Nadkarni V, Morley P, Warner DS, Topjian A, Venema AM, Branche CM, Szpilman D, Morizot-Leite L, Nitta M, Webber J, Beerman SB, Youn CS, Jost U, Quan L, Dezfulian C, Handley AJ, Hazinski MF, L?fgren B, Gr?sner JT. 2015 Revised Utstein-Style Recommended Guidelines for Uniform Reporting of Data From Drowning-Related Resuscitation: An ILCOR Advisory Statement. Circ Cardiovasc Qual Outcomes. 2017 Jul; 10(7). PMID: 28716971; PMCID: PMC6168199.
      Citations: 16     Fields:    Translation:Humans
    49. Dezfulian C, Trzeciak S, Girard TD. Lung-Brain Interaction after Cardiac Arrest? Am J Respir Crit Care Med. 2017 05 01; 195(9):1127-1128. PMID: 28459318.
      Citations: 1     Fields:    Translation:Humans
    50. Dezfulian C, Taft M, Corey C, Hill G, Krehel N, Rittenberger JC, Guyette FX, Shiva S. Biochemical signaling by remote ischemic conditioning of the arm versus thigh: Is one raise of the cuff enough? Redox Biol. 2017 08; 12:491-498. PMID: 28334684; PMCID: PMC5362138.
      Citations: 20     Fields:    Translation:HumansCells
    51. Vognsen M, Secher N, Dezfulian C, Andersen LW, Granfeldt A, Fabian-Jessing BK, L?fgren B. Contemporary animal models of cardiac arrest: A systematic review. Resuscitation. 2017 04; 113:115-123. PMID: 28214538.
      Citations: 17     Fields:    Translation:Animals
    52. Griffith B, Kochanek P, Dezfulian C. The benefits of youth are lost on the young cardiac arrest patient. F1000Res. 2017; 6:77. PMID: 28163912; PMCID: PMC5270587.
      Citations:    Fields:    
    53. Dezfulian C, Kenny E, Lamade A, Misse A, Krehel N, St Croix C, Kelley EE, Jackson TC, Uray T, Rackley J, Kochanek PM, Clark RS, Bayir H. Mechanistic characterization of nitrite-mediated neuroprotection after experimental cardiac arrest. J Neurochem. 2016 11; 139(3):419-431. PMID: 27507435; PMCID: PMC5247267.
      Citations: 14     Fields:    Translation:AnimalsCells
    54. Coppler PJ, Marill KA, Okonkwo DO, Shutter LA, Dezfulian C, Rittenberger JC, Callaway CW, Elmer J. Concordance of Brain and Core Temperature in Comatose Patients After Cardiac Arrest. Ther Hypothermia Temp Manag. 2016 Dec; 6(4):194-197. PMID: 27249337; PMCID: PMC6913784.
      Citations: 8     Fields:    Translation:Humans
    55. Winger DG, Coppler P, Sabedra AR, Murray H, Pinsky MR, Rittenberger JC, Reynolds JC, Dezfulian C, Janiczek JA. Hemodynamic Resuscitation Characteristics Associated with Improved Survival and Shock Resolution After Cardiac Arrest. Shock. 2016 06; 45(6):613-9. PMID: 26717104; PMCID: PMC4868655.
      Citations: 10     Fields:    Translation:Humans
    56. Lenchus JD, Biehl M, Cabrera J, Moraes AG, Dezfulian C. In-Hospital Management and Follow-Up Treatment of Venous Thromboembolism: Focus on New and Emerging Treatments. J Intensive Care Med. 2017 Jun; 32(5):299-311. PMID: 27179058.
      Citations: 4     Fields:    Translation:Humans
    57. Fidan E, Lewis J, Kline AE, Garman RH, Alexander H, Cheng JP, Bondi CO, Clark RS, Dezfulian C, Kochanek PM, Kagan VE, Bayir H. Repetitive Mild Traumatic Brain Injury in the Developing Brain: Effects on Long-Term Functional Outcome and Neuropathology. J Neurotrauma. 2016 Apr 01; 33(7):641-51. PMID: 26214116; PMCID: PMC4827290.
      Citations: 24     Fields:    Translation:AnimalsCells
    58. Chandrasekaran PN, Dezfulian C, Polderman KH. What is the right temperature to cool post-cardiac arrest patients? Crit Care. 2015 Nov 18; 19:406. PMID: 26577919; PMCID: PMC4650897.
      Citations: 3     Fields:    Translation:Humans
    59. Elmer J, Wang B, Melhem S, Pullalarevu R, Vaghasia N, Buddineni J, Rosario BL, Doshi AA, Callaway CW, Dezfulian C, University of Pittsburgh Post-Cardiac Arrest Service. Erratum to: Exposure to high concentrations of inspired oxygen does not worsen lung injury after cardiac arrest. Crit Care. 2015 Sep 15; 19:341. PMID: 26373827; PMCID: PMC4571112.
      Citations:    Fields:    
    60. Jentzer JC, Chonde MD, Dezfulian C. Myocardial Dysfunction and Shock after Cardiac Arrest. Biomed Res Int. 2015; 2015:314796. PMID: 26421284; PMCID: PMC4572400.
      Citations: 42     Fields:    Translation:Humans
    61. Uray T, Mayr FB, Fitzgibbon J, Rittenberger JC, Callaway CW, Drabek T, Fabio A, Angus DC, Kochanek PM, Dezfulian C. Socioeconomic factors associated with outcome after cardiac arrest in patients under the age of 65. Resuscitation. 2015 Aug; 93:14-9. PMID: 26003812; PMCID: PMC4856150.
      Citations: 10     Fields:    Translation:Humans
    62. Maberry DR, Holder A, Ogundele O, Quintero AM, Escobar D, Airgood H, Dezfulian C, Kenny E, Shiva S, Zuckerbraun B, Pinsky MR, Haugaa H, G?mez H, T?nnessen TI. Effects of inhalation of low-dose nitrite or carbon monoxide on post-reperfusion mitochondrial function and tissue injury in hemorrhagic shock swine. Crit Care. 2015 Apr 22; 19:184. PMID: 25899004; PMCID: PMC4422303.
      Citations: 4     Fields:    Translation:AnimalsCells
    63. Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM. The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice. J Cereb Blood Flow Metab. 2015 Mar 31; 35(4):655-66. PMID: 25586139; PMCID: PMC4420885.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    64. Horvat CM, Carcillo JA, Dezfulian C. Liquid fluorocarbon lavage to clear thrombus from the distal airways after severe pulmonary hemorrhage requiring extracorporeal life support (ECLS). Respir Med Case Rep. 2015; 15:7-8. PMID: 26236589; PMCID: PMC4501460.
    65. Elmer J, Wang B, Melhem S, Pullalarevu R, Pullalarevu R, Vaghasia N, Buddineni J, Rosario BL, Doshi AA, Callaway CW, Dezfulian C, University of Pittsburgh Post-Cardiac Arrest Service (PCAS). Exposure to high concentrations of inspired oxygen does not worsen lung injury after cardiac arrest. Crit Care. 2015 Mar 10; 19:105. PMID: 25888131; PMCID: PMC4371614.
      Citations: 8     Fields:    Translation:Humans
    66. Sabedra AR, Kristan J, Raina K, Holm MB, Callaway CW, Guyette FX, Dezfulian C, Doshi AA, Rittenberger JC, Post Cardiac Arrest Service. Neurocognitive outcomes following successful resuscitation from cardiac arrest. Resuscitation. 2015 May; 90:67-72. PMID: 25737082; PMCID: PMC4404201.
      Citations: 8     Fields:    Translation:Humans
    67. Dezfulian C. The clinical relevance of pediatric post-cardiac arrest myocardial dysfunction and hemodynamic instability. Pediatr Crit Care Med. 2015 Feb; 16(2):190-1. PMID: 25647128; PMCID: PMC4339094.
      Citations:    Fields:    Translation:Humans
    68. Coppler PJ, Elmer J, Calderon L, Sabedra A, Doshi AA, Callaway CW, Rittenberger JC, Dezfulian C, Post Cardiac Arrest Service. Validation of the Pittsburgh Cardiac Arrest Category illness severity score. Resuscitation. 2015 Apr; 89:86-92. PMID: 25636896; PMCID: PMC4580975.
      Citations: 55     Fields:    Translation:Humans
    69. Kochanek PM, Dezfulian C. Asphyxial cardiac arrest from drowning: giving E-CPR the cold shoulder. Resuscitation. 2015 Mar; 88:A7-8. PMID: 25576981.
      Citations:    Fields:    Translation:Humans
    70. Elmer J, Scutella M, Pullalarevu R, Wang B, Vaghasia N, Trzeciak S, Rosario-Rivera BL, Guyette FX, Rittenberger JC, Dezfulian C, Pittsburgh Post-Cardiac Arrest Service (PCAS). The association between hyperoxia and patient outcomes after cardiac arrest: analysis of a high-resolution database. Intensive Care Med. 2015 Jan; 41(1):49-57. PMID: 25472570; PMCID: PMC4337386.
      Citations: 68     Fields:    Translation:Humans
    71. Trzeciak S, Glaspey LJ, Dellinger RP, Durflinger P, Anderson K, Dezfulian C, Roberts BW, Chansky ME, Parrillo JE, Hollenberg SM. Randomized controlled trial of inhaled nitric oxide for the treatment of microcirculatory dysfunction in patients with sepsis*. Crit Care Med. 2014 Dec; 42(12):2482-92. PMID: 25080051.
      Citations: 15     Fields:    Translation:Humans
    72. Domsic RT, Dezfulian C, Shoushtari A, Ivanco D, Kenny E, Kwoh CK, Medsger TA, Champion HC. Endothelial dysfunction is present only in the microvasculature and microcirculation of early diffuse systemic sclerosis patients. Clin Exp Rheumatol. 2014 Nov-Dec; 32(6 Suppl 86):S-154-60. PMID: 25372799; PMCID: PMC4317362.
      Citations: 13     Fields:    Translation:Humans
    73. Da Silva YS, Horvat CM, Dezfulian C. Thiamin Deficiency as a Cause of Persistent Hyperlactatemia in a Parenteral Nutrition-Dependent Patient. JPEN J Parenter Enteral Nutr. 2015 Jul; 39(5):604-6. PMID: 25096548.
      Citations: 2     Fields:    Translation:Humans
    74. Murnin MR, Sonder P, Janssens GN, Henry CL, Polderman KH, Rittenberger JC, Dezfulian C, Post Cardiac Arrest Service. Determinants of heat generation in patients treated with therapeutic hypothermia following cardiac arrest. J Am Heart Assoc. 2014 Apr 29; 3(3):e000580. PMID: 24780205; PMCID: PMC4309044.
      Citations: 7     Fields:    Translation:Humans
    75. Lin HW, Gresia VL, Stradecki HM, Alekseyenko A, Dezfulian C, Neumann JT, Dave KR, Perez-Pinzon MA. Protein kinase C delta modulates endothelial nitric oxide synthase after cardiac arrest. J Cereb Blood Flow Metab. 2014 Apr; 34(4):613-20. PMID: 24447953; PMCID: PMC3982078.
      Citations: 8     Fields:    Translation:Animals
    76. Manole MD, Kochanek PM, Alexander H, Dezfulian C, Fink EL, Bell MJ, Clark RS, Bayir H. Brain tissue oxygen monitoring identifies cortical hypoxia and thalamic hyperoxia after experimental cardiac arrest in rats. Pediatr Res. 2014 Feb; 75(2):295-301. PMID: 24226633; PMCID: PMC3970819.
      Citations: 15     Fields:    Translation:Animals
    77. Jackson TC, Verrier JD, Drabek T, Janesko-Feldman K, Gillespie DG, Uray T, Dezfulian C, Clark RS, Jackson EK, Kochanek PM, Bayir H. Pharmacological inhibition of pleckstrin homology domain leucine-rich repeat protein phosphatase is neuroprotective: differential effects on astrocytes. J Pharmacol Exp Ther. 2013 Nov; 347(2):516-28. PMID: 24023368; PMCID: PMC3807060.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    78. Dezfulian C, Garrett M, Gonzalez NR. Clinical application of preconditioning and postconditioning to achieve neuroprotection. Transl Stroke Res. 2013 Feb; 4(1):19-24. PMID: 24323188; PMCID: PMC4224593.
      Citations: 35     Fields:    Translation:Humans
    79. Munoz-Price LS, Dezfulian C, Wyckoff M, Lenchus JD, Rosalsky M, Birnbach DJ, Arheart KL. Effectiveness of stepwise interventions targeted to decrease central catheter-associated bloodstream infections. Crit Care Med. 2012 May; 40(5):1464-9. PMID: 22511128.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    80. Dezfulian C, Alekseyenko A, Dave KR, Raval AP, Do R, Kim F, Perez-Pinzon MA. Nitrite therapy is neuroprotective and safe in cardiac arrest survivors. Nitric Oxide. 2012 May 15; 26(4):241-50. PMID: 22484664; PMCID: PMC4337393.
      Citations: 24     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    81. Dave KR, Bhattacharya SK, Saul I, DeFazio RA, Dezfulian C, Lin HW, Raval AP, Perez-Pinzon MA. Activation of protein kinase C delta following cerebral ischemia leads to release of cytochrome C from the mitochondria via bad pathway. PLoS One. 2011; 6(7):e22057. PMID: 21789211; PMCID: PMC3137627.
      Citations: 14     Fields:    Translation:AnimalsCells
    82. Munoz-Price LS, Ariza-Heredia E, Adams S, Olivier M, Francois L, Socarras M, Coro G, Adedokun A, Pappas T, Tamayo M, McDade R, Dezfulian C. Use of UV powder for surveillance to improve environmental cleaning. Infect Control Hosp Epidemiol. 2011 Mar; 32(3):283-5. PMID: 21460514.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    83. Dezfulian C, Trzeciak S. Reduced arteriovenous nitrite gradients associated with sepsis. Crit Care Med. 2010 Apr; 38(4):1214-5. PMID: 20335702.
      Citations:    Fields:    Translation:Humans
    84. Dezfulian C, Cobas M, Pretto E. Race and survival after cardiac arrest. JAMA. 2010 Jan 13; 303(2):130; author reply 130-1. PMID: 20068202.
      Citations:    Fields:    Translation:Humans
    85. Dezfulian C, Shiva S, Alekseyenko A, Pendyal A, Beiser DG, Munasinghe JP, Anderson SA, Chesley CF, Vanden Hoek TL, Gladwin MT. Nitrite therapy after cardiac arrest reduces reactive oxygen species generation, improves cardiac and neurological function, and enhances survival via reversible inhibition of mitochondrial complex I. Circulation. 2009 Sep 08; 120(10):897-905. PMID: 19704094; PMCID: PMC2755623.
      Citations: 87     Fields:    Translation:Animals
    86. Dezfulian C, Raat N, Shiva S, Gladwin MT. Role of the anion nitrite in ischemia-reperfusion cytoprotection and therapeutics. Cardiovasc Res. 2007 Jul 15; 75(2):327-38. PMID: 17568573; PMCID: PMC2002522.
      Citations: 79     Fields:    Translation:HumansAnimalsCells
    87. Gladwin MT, Raat NJ, Shiva S, Dezfulian C, Hogg N, Kim-Shapiro DB, Patel RP. Nitrite as a vascular endocrine nitric oxide reservoir that contributes to hypoxic signaling, cytoprotection, and vasodilation. Am J Physiol Heart Circ Physiol. 2006 Nov; 291(5):H2026-35. PMID: 16798825.
      Citations: 117     Fields:    Translation:HumansAnimals
    88. Dezfulian C, Raat NJ, Gladwin MT. A pharmacogenomic study of atorvastatin effects on eNOS activity: do "statins" modulate blood nitrite levels and intravascular oxidant stress in susceptible individuals? Free Radic Biol Med. 2006 Oct 01; 41(7):1041-3. PMID: 16962928.
      Citations: 1     Fields:    Translation:HumansAnimals
    89. Safdar N, Dezfulian C, Collard HR, Saint S. Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med. 2005 Oct; 33(10):2184-93. PMID: 16215368.
      Citations: 243     Fields:    Translation:Humans
    90. Dezfulian C, Shojania K, Collard HR, Kim HM, Matthay MA, Saint S. Subglottic secretion drainage for preventing ventilator-associated pneumonia: a meta-analysis. Am J Med. 2005 Jan; 118(1):11-8. PMID: 15639202.
      Citations: 44     Fields:    Translation:Humans
    91. O'Grady NP, Dezfulian C. The femoral site as first choice for central venous access? Not so fast. Crit Care Med. 2005 Jan; 33(1):234-5. PMID: 15644678.
      Citations: 1     Fields:    Translation:Humans
    92. Dezfulian C, Lavelle J, Nallamothu BK, Kaufman SR, Saint S. Rates of infection for single-lumen versus multilumen central venous catheters: a meta-analysis. Crit Care Med. 2003 Sep; 31(9):2385-90. PMID: 14501971.
      Citations: 22     Fields:    Translation:HumansPHPublic Health
    93. Wassenberg JJ, Dezfulian C, Nicchitta CV. Receptor mediated and fluid phase pathways for internalization of the ER Hsp90 chaperone GRP94 in murine macrophages. J Cell Sci. 1999 Jul; 112 ( Pt 13):2167-75. PMID: 10362546.
      Citations: 20     Fields:    Translation:AnimalsCellsPHPublic Health
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