LIYA HU

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Taylor DM, Anglin J, Hu L, Wang L, Sankaran B, Wang J, Matzuk MM, Prasad BVV, Palzkill T. Unique Diacidic Fragments Inhibit the OXA-48 Carbapenemase and Enhance the Killing of Escherichia coli Producing OXA-48. ACS Infect Dis. 2021 Nov 24. PMID: 34817169.
      Citations:    Fields:    
    2. Zhao B, Hu L, Song Y, Patil K, Ramani S, Atmar RL, Estes MK, Prasad BVV. Norovirus Protease Structure and Antivirals Development. Viruses. 2021 Oct 14; 13(10). PMID: 34696498.
      Citations:    Fields:    
    3. Tenge VR, Hu L, Prasad BVV, Larson G, Atmar RL, Estes MK, Ramani S. Glycan Recognition in Human Norovirus Infections. Viruses. 2021 Oct 14; 13(10). PMID: 34696500.
      Citations:    Fields:    
    4. Furey IM, Mehta SC, Sankaran B, Hu L, Prasad BVV, Palzkill T. Local interactions with the Glu166 base and the conformation of an active site loop play key roles in carbapenem hydrolysis by the KPC-2 ß-lactamase. J Biol Chem. 2021 Jan-Jun; 296:100799. PMID: 34022225.
      Citations: 1     Fields:    Translation:HumansCells
    5. Huang W, Soeung V, Boragine DM, Hu L, Prasad BVV, Estes MK, Atmar RL, Palzkill T. High-Resolution Mapping of Human Norovirus Antigens via Genomic Phage Display Library Selections and Deep Sequencing. J Virol. 2020 12 09; 95(1). PMID: 33055250.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    6. Soeung V, Lu S, Hu L, Judge A, Sankaran B, Prasad BVV, Palzkill T. A drug-resistant ß-lactamase variant changes the conformation of its active-site proton shuttle to alter substrate specificity and inhibitor potency. J Biol Chem. 2020 12 25; 295(52):18239-18255. PMID: 33109613.
      Citations: 2     Fields:    Translation:Cells
    7. Brown CA, Hu L, Sun Z, Patel MP, Singh S, Porter JR, Sankaran B, Prasad BVV, Bowman GR, Palzkill T. Antagonism between substitutions in ß-lactamase explains a path not taken in the evolution of bacterial drug resistance. J Biol Chem. 2020 05 22; 295(21):7376-7390. PMID: 32299911.
      Citations: 4     Fields:    Translation:Cells
    8. Kumar D, Yu X, Crawford SE, Moreno R, Jakana J, Sankaran B, Anish R, Kaundal S, Hu L, Estes MK, Wang Z, Prasad BVV. 2.7 Å cryo-EM structure of rotavirus core protein VP3, a unique capping machine with a helicase activity. Sci Adv. 2020 Apr; 6(16):eaay6410. PMID: 32494598.
      Citations: 1     Fields:    
    9. Taylor DM, Anglin J, Park S, Ucisik MN, Faver JC, Simmons N, Jin Z, Palaniappan M, Nyshadham P, Li F, Campbell J, Hu L, Sankaran B, Prasad BVV, Huang H, Matzuk MM, Palzkill T. Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries. ACS Infect Dis. 2020 05 08; 6(5):1214-1227. PMID: 32182432.
      Citations: 8     Fields:    Translation:Cells
    10. Mitra S, Kumar D, Hu L, Sankaran B, Moosa MM, Rice AP, Ferreon JC, Ferreon ACM, Prasad BVV. Influenza A Virus Protein NS1 Exhibits Strain-Independent Conformational Plasticity. J Virol. 2019 11 01; 93(21). PMID: 31375595.
      Citations: 6     Fields:    Translation:Cells
    11. Viskovska MA, Zhao B, Shanker S, Choi JM, Deng L, Song Y, Palzkill T, Hu L, Estes MK, Venkataram Prasad BV. GII.4 Norovirus Protease Shows pH-Sensitive Proteolysis with a Unique Arg-His Pairing in the Catalytic Site. J Virol. 2019 03 15; 93(6). PMID: 30626675.
      Citations: 6     Fields:    Translation:HumansCells
    12. Criglar JM, Anish R, Hu L, Crawford SE, Sankaran B, Prasad BVV, Estes MK. Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories. Proc Natl Acad Sci U S A. 2018 12 18; 115(51):E12015-E12023. PMID: 30509975.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    13. Ramani S, Stewart CJ, Laucirica DR, Ajami NJ, Robertson B, Autran CA, Shinge D, Rani S, Anandan S, Hu L, Ferreon JC, Kuruvilla KA, Petrosino JF, Venkataram Prasad BV, Bode L, Kang G, Estes MK. Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection. Nat Commun. 2018 11 27; 9(1):5010. PMID: 30479342.
      Citations: 39     Fields:    Translation:HumansCells
    14. Sun Z, Hu L, Sankaran B, Prasad BVV, Palzkill T. Differential active site requirements for NDM-1 ß-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics. Nat Commun. 2018 10 30; 9(1):4524. PMID: 30375382.
      Citations: 17     Fields:    Translation:Cells
    15. Patel MP, Hu L, Brown CA, Sun Z, Adamski CJ, Stojanoski V, Sankaran B, Prasad BVV, Palzkill T. Synergistic effects of functionally distinct substitutions in ß-lactamase variants shed light on the evolution of bacterial drug resistance. J Biol Chem. 2018 11 16; 293(46):17971-17984. PMID: 30275013.
      Citations: 7     Fields:    Translation:Cells
    16. Hu L, Sankaran B, Laucirica DR, Patil K, Salmen W, Ferreon ACM, Tsoi PS, Lasanajak Y, Smith DF, Ramani S, Atmar RL, Estes MK, Ferreon JC, Prasad BVV. Glycan recognition in globally dominant human rotaviruses. Nat Commun. 2018 07 06; 9(1):2631. PMID: 29980685.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    17. Shanker S, Hu L, Ramani S, Atmar RL, Estes MK, Venkataram Prasad BV. Structural features of glycan recognition among viral pathogens. Curr Opin Struct Biol. 2017 06; 44:211-218. PMID: 28591681.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    18. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 29784777.
      Citations: 4     Fields:    Translation:Cells
    19. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 24198401.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    20. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 26420502.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    21. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 31992706.
      Citations: 3     Fields:    Translation:Cells
    22. Zhuang H, Bai J, Chang JY, Yuan Z, Wang P. MTOR inhibition reversed drug resistance after combination radiation with erlotinib in lung adenocarcinoma. Oncotarget. 2016 Dec 20; 7(51):84688-84694. PMID: 32433610.
      Citations: 9     Fields:    Translation:HumansCells
    23. Ramani S, Hu L, Venkataram Prasad BV, Estes MK. Diversity in Rotavirus-Host Glycan Interactions: A "Sweet" Spectrum. Cell Mol Gastroenterol Hepatol. 2016 May; 2(3):263-273. PMID: 28090561.
      Citations: 26     Fields:    
    24. Stojanoski V, Chow DC, Hu L, Sankaran B, Gilbert HF, Prasad BV, Palzkill T. A triple mutant in the O-loop of TEM-1 ß-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis. J Biol Chem. 2015 Apr 17; 290(16):10382-94. PMID: 25713062.
      Citations: 15     Fields:    Translation:Cells
    25. Viskovska M, Anish R, Hu L, Chow DC, Hurwitz AM, Brown NG, Palzkill T, Estes MK, Prasad BV. Probing the sites of interactions of rotaviral proteins involved in replication. J Virol. 2014 Nov; 88(21):12866-81. PMID: 25165107.
      Citations: 11     Fields:    Translation:Cells
    26. Venkataram Prasad BV, Shanker S, Hu L, Choi JM, Crawford SE, Ramani S, Czako R, Atmar RL, Estes MK. Structural basis of glycan interaction in gastroenteric viral pathogens. Curr Opin Virol. 2014 Aug; 7:119-27. PMID: 25073118.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    27. Ramani S, Cortes-Penfield NW, Hu L, Crawford SE, Czako R, Smith DF, Kang G, Ramig RF, Le Pendu J, Prasad BV, Estes MK. The VP8* domain of neonatal rotavirus strain G10P[11] binds to type II precursor glycans. J Virol. 2013 Jul; 87(13):7255-64. PMID: 23616650.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    28. Hu L, Chow DC, Patton JT, Palzkill T, Estes MK, Prasad BV. Crystallographic Analysis of Rotavirus NSP2-RNA Complex Reveals Specific Recognition of 5' GG Sequence for RTPase Activity. J Virol. 2012 Oct; 86(19):10547-57. PMID: 22811529.
      Citations: 13     Fields:    Translation:Cells
    29. Hu L, Crawford SE, Hyser JM, Estes MK, Prasad BV. Rotavirus non-structural proteins: structure and function. Curr Opin Virol. 2012 Aug; 2(4):380-8. PMID: 22789743.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    30. Hu L, Crawford SE, Czako R, Cortes-Penfield NW, Smith DF, Le Pendu J, Estes MK, Prasad BV. Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen. Nature. 2012 Apr 15; 485(7397):256-9. PMID: 22504179.
      Citations: 127     Fields:    Translation:HumansAnimalsCells
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