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Institution

Guowei Gu

TitleInstructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
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    Other Positions
    TitleInstructor
    InstitutionBaylor College of Medicine
    DepartmentBreast Center
    DivisionBreast Cancer Center


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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Stossi F, Dandekar RD, Mancini MG, Gu G, Fuqua SAW, Nardone A, De Angelis C, Fu X, Schiff R, Bedford MT, Xu W, Johansson HE, Stephan CC, Mancini MA. Estrogen-induced transcription at individual alleles is independent of receptor level and active conformation but can be modulated by coactivators activity. Nucleic Acids Res. 2020 02 28; 48(4):1800-1810. PMID: 31930333.
      View in: PubMed
    2. Dustin D, Gu G, Fuqua SAW. ESR1 mutations in breast cancer. Cancer. 2019 Nov 01; 125(21):3714-3728. PMID: 31318440.
      View in: PubMed
    3. Gates LA, Gu G, Chen Y, Rohira AD, Lei JT, Hamilton RA, Yu Y, Lonard DM, Wang J, Wang SP, Edwards DG, Lavere PF, Shao J, Yi P, Jain A, Jung SY, Malovannaya A, Li S, Shao J, Roeder RG, Ellis MJ, Qin J, Fuqua SAW, O'Malley BW, Foulds CE. Proteomic profiling identifies key coactivators utilized by mutant ERa proteins as potential new therapeutic targets. Oncogene. 2018 08; 37(33):4581-4598. PMID: 29748621.
      View in: PubMed
    4. Pejerrey SM, Dustin D, Kim JA, Gu G, Rechoum Y, Fuqua SAW. The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer. Horm Cancer. 2018 08; 9(4):215-228. PMID: 29736566.
      View in: PubMed
    5. Gelsomino L, Gu G, Rechoum Y, Beyer AR, Pejerrey SM, Tsimelzon A, Wang T, Huffman K, Ludlow A, Andò S, Fuqua SAW. Erratum to: ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling. Breast Cancer Res Treat. 2017 06; 163(3):639-640. PMID: 28439737.
      View in: PubMed
    6. Gu G, Dustin D, Fuqua SA. Targeted therapy for breast cancer and molecular mechanisms of resistance to treatment. Curr Opin Pharmacol. 2016 12; 31:97-103. PMID: 27883943.
      View in: PubMed
    7. Fuqua SA, Rechoum Y, Gu G. ESR1 Mutations in Cell-Free DNA of Breast Cancer: Predictive "Tip of the Iceberg". JAMA Oncol. 2016 10 01; 2(10):1315-1316. PMID: 27532824.
      View in: PubMed
    8. Gelsomino L, Gu G, Rechoum Y, Beyer AR, Pejerrey SM, Tsimelzon A, Wang T, Huffman K, Ludlow A, Andò S, Fuqua SAW. ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling. Breast Cancer Res Treat. 2016 06; 157(2):253-265. PMID: 27178332.
      View in: PubMed
    9. Gu G, Fuqua SA. ESR1 Mutations in Breast Cancer: Proof-of-Concept Challenges Clinical Action. Clin Cancer Res. 2016 Mar 01; 22(5):1034-6. PMID: 26700205.
      View in: PubMed
    10. Ciupek A, Rechoum Y, Gu G, Gelsomino L, Beyer AR, Brusco L, Covington KR, Tsimelzon A, Fuqua SA. Androgen receptor promotes tamoxifen agonist activity by activation of EGFR in ERa-positive breast cancer. Breast Cancer Res Treat. 2015 Nov; 154(2):225-37. PMID: 26487496.
      View in: PubMed
    11. Gu G, Gelsomino L, Covington KR, Beyer AR, Wang J, Rechoum Y, Huffman K, Carstens R, Andò S, Fuqua SA. Targeting thyroid hormone receptor beta in triple-negative breast cancer. Breast Cancer Res Treat. 2015 Apr; 150(3):535-45. PMID: 25820519.
      View in: PubMed
    12. Blackmore JK, Karmakar S, Gu G, Chaubal V, Wang L, Li W, Smith CL. The SMRT coregulator enhances growth of estrogen receptor-a-positive breast cancer cells by promotion of cell cycle progression and inhibition of apoptosis. Endocrinology. 2014 Sep; 155(9):3251-61. PMID: 24971610.
      View in: PubMed
    13. Fuqua SA, Gu G, Rechoum Y. Estrogen receptor (ER) a mutations in breast cancer: hidden in plain sight. Breast Cancer Res Treat. 2014 Feb; 144(1):11-9. PMID: 24487689.
      View in: PubMed
    14. Gu G, Barone I, Gelsomino L, Giordano C, Bonofiglio D, Statti G, Menichini F, Catalano S, Andò S. Oldenlandia diffusa extracts exert antiproliferative and apoptotic effects on human breast cancer cells through ERa/Sp1-mediated p53 activation. J Cell Physiol. 2012 Oct; 227(10):3363-72. PMID: 22213398.
      View in: PubMed
    15. Selever J, Gu G, Lewis MT, Beyer A, Herynk MH, Covington KR, Tsimelzon A, Dontu G, Provost P, Di Pietro A, Boumendjel A, Albain K, Miele L, Weiss H, Barone I, Ando S, Fuqua SA. Dicer-mediated upregulation of BCRP confers tamoxifen resistance in human breast cancer cells. Clin Cancer Res. 2011 Oct 15; 17(20):6510-21. PMID: 21878538.
      View in: PubMed
    16. Barone I, Brusco L, Gu G, Selever J, Beyer A, Covington KR, Tsimelzon A, Wang T, Hilsenbeck SG, Chamness GC, Andò S, Fuqua SA. Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a. J Natl Cancer Inst. 2011 Apr 06; 103(7):538-52. PMID: 21447808.
      View in: PubMed
    17. Catalano S, Malivindi R, Giordano C, Gu G, Panza S, Bonofiglio D, Lanzino M, Sisci D, Panno ML, Andò S. Farnesoid X receptor, through the binding with steroidogenic factor 1-responsive element, inhibits aromatase expression in tumor Leydig cells. J Biol Chem. 2010 Feb 19; 285(8):5581-93. PMID: 20026603.
      View in: PubMed
    18. Catalano S, Barone I, Giordano C, Rizza P, Qi H, Gu G, Malivindi R, Bonofiglio D, Andò S. Rapid estradiol/ERalpha signaling enhances aromatase enzymatic activity in breast cancer cells. Mol Endocrinol. 2009 Oct; 23(10):1634-45. PMID: 19556341.
      View in: PubMed
    19. Catalano S, Giordano C, Rizza P, Gu G, Barone I, Bonofiglio D, Giordano F, Malivindi R, Gaccione D, Lanzino M, De Amicis F, Andò S. Evidence that leptin through STAT and CREB signaling enhances cyclin D1 expression and promotes human endometrial cancer proliferation. J Cell Physiol. 2009 Mar; 218(3):490-500. PMID: 18988190.
      View in: PubMed
    20. Catalano S, Rizza P, Gu G, Barone I, Giordano C, Marsico S, Casaburi I, Middea E, Lanzino M, Pellegrino M, Andò S. Fas ligand expression in TM4 Sertoli cells is enhanced by estradiol "in situ" production. J Cell Physiol. 2007 May; 211(2):448-56. PMID: 17167783.
      View in: PubMed
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