GARY CHAMNESS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentBreast Center
    DivisionBreast Cancer Center


    Collapse Research 
    Collapse research activities and funding
    P01CA030195     (OESTERREICH, STEFFI)Aug 1, 1998 - Mar 31, 2010
    NIH/NCI
    Novel Gene Networks in Breast Development and Cancer
    Role: Co-Principal Investigator

    R01CA046900     (CHAMNESS, GARY C)Mar 1, 1988 - Feb 29, 1992
    NIH/NCI
    FLUORESCENT STEROID CONJUGATES FOR ER AND PR STUDIES
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Fu X, Pereira R, De Angelis C, Veeraraghavan J, Nanda S, Qin L, Cataldo ML, Sethunath V, Mehravaran S, Gutierrez C, Chamness GC, Feng Q, O'Malley BW, Selenica P, Weigelt B, Reis-Filho JS, Cohen O, Wagle N, Nardone A, Jeselsohn R, Brown M, Rimawi MF, Osborne CK, Schiff R. FOXA1 upregulation promotes enhancer and transcriptional reprogramming in endocrine-resistant breast cancer. Proc Natl Acad Sci U S A. 2019 Dec 26; 116(52):26823-26834. PMID: 31826955; PMCID: PMC6936436.
      Citations: 34     Fields:    
    2. Sethunath V, Hu H, De Angelis C, Veeraraghavan J, Qin L, Wang N, Wang T, Fu X, Nardone A, Pereira R, Nanda S, Griffith OL, Tsimelzon A, Shaw C, Chamness GC, Reis-Filho JS, Weigelt B, Heiser LM, Hilsenbeck SG, Huang S, Rimawi MF, Gray JW, Osborne CK, Schiff R, Simon LM. Targeting the Mevalonate Pathway to Overcome Acquired Anti-HER2 Treatment Resistance in Breast Cancer. Mol Cancer Res. 2019 11; 17(11):2318-2330. PMID: 31420371; PMCID: PMC6825570.
      Citations: 19     Fields:    Translation:HumansCells
    3. Nardone A, Weir H, Delpuech O, Brown H, De Angelis C, Cataldo ML, Fu X, Shea MJ, Mitchell T, Veeraraghavan J, Nagi C, Pilling M, Rimawi MF, Trivedi M, Hilsenbeck SG, Chamness GC, Jeselsohn R, Osborne CK, Schiff R. The oral selective oestrogen receptor degrader (SERD) AZD9496 is comparable to fulvestrant in antagonising ER and circumventing endocrine resistance. Br J Cancer. 2019 02; 120(3):331-339. PMID: 30555156; PMCID: PMC6353941.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    4. Xu X, De Angelis C, Burke KA, Nardone A, Hu H, Qin L, Veeraraghavan J, Sethunath V, Heiser LM, Wang N, Ng CKY, Chen ES, Renwick A, Wang T, Nanda S, Shea M, Mitchell T, Rajendran M, Waters I, Zabransky DJ, Scott KL, Gutierrez C, Nagi C, Geyer FC, Chamness GC, Park BH, Shaw CA, Hilsenbeck SG, Rimawi MF, Gray JW, Weigelt B, Reis-Filho JS, Osborne CK, Schiff R. HER2 Reactivation through Acquisition of the HER2 L755S Mutation as a Mechanism of Acquired Resistance to HER2-targeted Therapy in HER2+ Breast Cancer. Clin Cancer Res. 2017 Sep 01; 23(17):5123-5134. PMID: 28487443; PMCID: PMC5762201.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    5. Giuliano M, Hu H, Wang YC, Fu X, Nardone A, Herrera S, Mao S, Contreras A, Gutierrez C, Wang T, Hilsenbeck SG, De Angelis C, Wang NJ, Heiser LM, Gray JW, Pavlick AC, Trivedi MV, Chamness GC, Chang JC, Osborne CK, Rimawi MF, Schiff R, Lopez-Tarruella S. Upregulation of ER Signaling as an Adaptive Mechanism of Cell Survival in HER2-Positive Breast Tumors Treated with Anti-HER2 Therapy. Clin Cancer Res. 2015 Sep 01; 21(17):3995-4003. PMID: 26015514; PMCID: PMC4558260.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    6. Suo J, Medina D, Herrera S, Zheng ZY, Jin L, Chamness GC, Contreras A, Gutierrez C, Hilsenbeck S, Umar A, Foekens JA, Hanash S, Schiff R, Zhang XH, Chang EC. Int6 reduction activates stromal fibroblasts to enhance transforming activity in breast epithelial cells. Cell Biosci. 2015; 5:10. PMID: 25774287; PMCID: PMC4359526.
      Citations: 5     
    7. Veeraraghavan J, Tan Y, Cao XX, Kim JA, Wang X, Chamness GC, Maiti SN, Cooper LJ, Edwards DP, Contreras A, Hilsenbeck SG, Chang EC, Schiff R, Wang XS. Recurrent ESR1-CCDC170 rearrangements in an aggressive subset of oestrogen receptor-positive breast cancers. Nat Commun. 2014 Aug 07; 5:4577. PMID: 25099679; PMCID: PMC4130357.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    8. Wang YC, Morrison G, Gillihan R, Guo J, Ward RM, Fu X, Botero MF, Healy NA, Hilsenbeck SG, Phillips GL, Chamness GC, Rimawi MF, Osborne CK, Schiff R. Different mechanisms for resistance to trastuzumab versus lapatinib in HER2-positive breast cancers--role of estrogen receptor and HER2 reactivation. Breast Cancer Res. 2011; 13(6):R121. PMID: 22123186; PMCID: PMC3326563.
      Citations: 119     Fields:    Translation:HumansAnimalsCells
    9. Bu W, Chen J, Morrison GD, Huang S, Creighton CJ, Huang J, Chamness GC, Hilsenbeck SG, Roop DR, Leavitt AD, Li Y. Keratin 6a marks mammary bipotential progenitor cells that can give rise to a unique tumor model resembling human normal-like breast cancer. Oncogene. 2011 Oct 27; 30(43):4399-409. PMID: 21532625; PMCID: PMC3156856.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    10. Barone I, Brusco L, Gu G, Selever J, Beyer A, Covington KR, Tsimelzon A, Wang T, Hilsenbeck SG, Chamness GC, Fuqua SA, And? S. Loss of Rho GDIa and resistance to tamoxifen via effects on estrogen receptor a. J Natl Cancer Inst. 2011 Apr 06; 103(7):538-52. PMID: 21447808; PMCID: PMC3071355.
      Citations: 31     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    11. Dave B, Migliaccio I, Gutierrez MC, Wu MF, Chamness GC, Wong H, Narasanna A, Chakrabarty A, Hilsenbeck SG, Huang J, Rimawi M, Schiff R, Arteaga C, Osborne CK, Chang JC. Loss of phosphatase and tensin homolog or phosphoinositol-3 kinase activation and response to trastuzumab or lapatinib in human epidermal growth factor receptor 2-overexpressing locally advanced breast cancers. J Clin Oncol. 2011 Jan 10; 29(2):166-73. PMID: 21135276; PMCID: PMC3058274.
      Citations: 123     Fields:    Translation:HumansCells
    12. Rodriguez AA, Makris A, Wu MF, Rimawi M, Froehlich A, Dave B, Hilsenbeck SG, Chamness GC, Lewis MT, Dobrolecki LE, Jain D, Sahoo S, Osborne CK, Chang JC. DNA repair signature is associated with anthracycline response in triple negative breast cancer patients. Breast Cancer Res Treat. 2010 Aug; 123(1):189-96. PMID: 20582464.
      Citations: 30     Fields:    Translation:HumansCells
    13. Rimawi MF, Shetty PB, Weiss HL, Schiff R, Osborne CK, Chamness GC, Elledge RM. Epidermal growth factor receptor expression in breast cancer association with biologic phenotype and clinical outcomes. Cancer. 2010 Mar 01; 116(5):1234-42. PMID: 20082448; PMCID: PMC2829330.
      Citations: 91     Fields:    Translation:Humans
    14. De Amicis F, Thirugnansampanthan J, Cui Y, Selever J, Beyer A, Parra I, Weigel NL, Herynk MH, Tsimelzon A, Lewis MT, Chamness GC, Hilsenbeck SG, Fuqua SA, And? S. Androgen receptor overexpression induces tamoxifen resistance in human breast cancer cells. Breast Cancer Res Treat. 2010 May; 121(1):1-11. PMID: 19533338; PMCID: PMC2995248.
      Citations: 86     Fields:    Translation:HumansAnimalsCells
    15. Li X, Lewis MT, Huang J, Gutierrez C, Osborne CK, Wu MF, Hilsenbeck SG, Pavlick A, Zhang X, Chamness GC, Wong H, Rosen J, Chang JC. Intrinsic resistance of tumorigenic breast cancer cells to chemotherapy. J Natl Cancer Inst. 2008 May 07; 100(9):672-9. PMID: 18445819.
      Citations: 817     Fields:    Translation:Humans
    16. Creighton CJ, Kent Osborne C, van de Vijver MJ, Foekens JA, Klijn JG, Horlings HM, Nuyten D, Wang Y, Zhang Y, Chamness GC, Hilsenbeck SG, Lee AV, Schiff R. Molecular profiles of progesterone receptor loss in human breast tumors. Breast Cancer Res Treat. 2009 Mar; 114(2):287-99. PMID: 18425577; PMCID: PMC2635926.
      Citations: 41     Fields:    Translation:HumansCells
    17. Chang JC, Makris A, Gutierrez MC, Hilsenbeck SG, Hackett JR, Jeong J, Liu ML, Baker J, Clark-Langone K, Baehner FL, Sexton K, Mohsin S, Gray T, Alvarez L, Chamness GC, Osborne CK, Shak S. Gene expression patterns in formalin-fixed, paraffin-embedded core biopsies predict docetaxel chemosensitivity in breast cancer patients. Breast Cancer Res Treat. 2008 Mar; 108(2):233-40. PMID: 17468949.
      Citations: 42     Fields:    Translation:HumansCTClinical Trials
    18. Tham YL, Gomez LF, Mohsin S, Gutierrez MC, Weiss H, Hilsenbeck SG, Elledge RM, Chamness GC, Osborne CK, Allred DC, Chang JC. Clinical response to neoadjuvant docetaxel predicts improved outcome in patients with large locally advanced breast cancers. Breast Cancer Res Treat. 2005 Dec; 94(3):279-84. PMID: 16261403.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    19. Zhang X, Podsypanina K, Huang S, Mohsin SK, Chamness GC, Hatsell S, Cowin P, Schiff R, Li Y. Estrogen receptor positivity in mammary tumors of Wnt-1 transgenic mice is influenced by collaborating oncogenic mutations. Oncogene. 2005 Jun 16; 24(26):4220-31. PMID: 15824740.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    20. Chang JC, Wooten EC, Tsimelzon A, Hilsenbeck SG, Gutierrez MC, Tham YL, Kalidas M, Elledge R, Mohsin S, Osborne CK, Chamness GC, Allred DC, Lewis MT, Wong H, O'Connell P. Patterns of resistance and incomplete response to docetaxel by gene expression profiling in breast cancer patients. J Clin Oncol. 2005 Feb 20; 23(6):1169-77. PMID: 15718313.
      Citations: 59     Fields:    Translation:Humans
    21. Mohsin SK, Weiss HL, Gutierrez MC, Chamness GC, Schiff R, Digiovanna MP, Wang CX, Hilsenbeck SG, Osborne CK, Allred DC, Elledge R, Chang JC. Neoadjuvant trastuzumab induces apoptosis in primary breast cancers. J Clin Oncol. 2005 Apr 10; 23(11):2460-8. PMID: 15710948.
      Citations: 96     Fields:    Translation:HumansCTClinical Trials
    22. Lee AV, Chamness G, Oesterreich S. 26th Annual San Antonio Breast Cancer Symposium, San Antonio, Texas, USA, 3-6 December 2003: update on preclinical and translational research. Breast Cancer Res. 2004 Jan 19; 6(2):E10. PMID: 14979916; PMCID: PMC400657.
      Citations:    Fields:    Translation:HumansCells
    23. Chang JC, Wooten EC, Tsimelzon A, Hilsenbeck SG, Gutierrez MC, Elledge R, Mohsin S, Osborne CK, Chamness GC, Allred DC, O'Connell P. Gene expression profiling for the prediction of therapeutic response to docetaxel in patients with breast cancer. Lancet. 2003 Aug 02; 362(9381):362-9. PMID: 12907009.
      Citations: 193     Fields:    Translation:Humans
    24. Schiff R, Chamness GC, Brown PH. Advances in breast cancer treatment and prevention: preclinical studies on aromatase inhibitors and new selective estrogen receptor modulators (SERMs). Breast Cancer Res. 2003; 5(5):228-31. PMID: 12927029; PMCID: PMC314430.
      Citations: 8     Fields:    Translation:HumansAnimals
    25. Osborne CK, Bardou V, Hopp TA, Chamness GC, Hilsenbeck SG, Fuqua SA, Wong J, Allred DC, Clark GM, Schiff R. Role of the estrogen receptor coactivator AIB1 (SRC-3) and HER-2/neu in tamoxifen resistance in breast cancer. J Natl Cancer Inst. 2003 Mar 05; 95(5):353-61. PMID: 12618500.
      Citations: 257     Fields:    Translation:HumansCells
    26. Chang J, Clark GM, Allred DC, Mohsin S, Chamness G, Elledge RM. Survival of patients with metastatic breast carcinoma: importance of prognostic markers of the primary tumor. Cancer. 2003 Feb 01; 97(3):545-53. PMID: 12548595.
      Citations: 81     Fields:    Translation:Humans
    27. Schiff R, Reddy P, Ahotupa M, Coronado-Heinsohn E, Grim M, Hilsenbeck SG, Lawrence R, Deneke S, Herrera R, Chamness GC, Fuqua SA, Brown PH, Osborne CK. Oxidative stress and AP-1 activity in tamoxifen-resistant breast tumors in vivo. J Natl Cancer Inst. 2000 Dec 06; 92(23):1926-34. PMID: 11106684.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    28. Zellars RC, Hilsenbeck SG, Clark GM, Allred DC, Herman TS, Chamness GC, Elledge RM. Prognostic value of p53 for local failure in mastectomy-treated breast cancer patients. J Clin Oncol. 2000 May; 18(9):1906-13. PMID: 10784631.
      Citations: 10     Fields:    Translation:Humans
    29. Hilsenbeck SG, Ravdin PM, de Moor CA, Chamness GC, Osborne CK, Clark GM. Time-dependence of hazard ratios for prognostic factors in primary breast cancer. Breast Cancer Res Treat. 1998; 52(1-3):227-37. PMID: 10066085.
      Citations: 59     Fields:    Translation:HumansCells
    30. Clark GM, Allred DC, Hilsenbeck SG, Chamness GC, Osborne CK, Jones D, Lee WH. Mitosin (a new proliferation marker) correlates with clinical outcome in node-negative breast cancer. Cancer Res. 1997 Dec 15; 57(24):5505-8. PMID: 9407959.
      Citations: 15     Fields:    Translation:HumansAnimals
    31. Oesterreich S, Hilsenbeck SG, Ciocca DR, Allred DC, Clark GM, Chamness GC, Osborne CK, Fuqua SA. The small heat shock protein HSP27 is not an independent prognostic marker in axillary lymph node-negative breast cancer patients. Clin Cancer Res. 1996 Jul; 2(7):1199-206. PMID: 9816288.
      Citations: 8     Fields:    Translation:Humans
    32. Ravdin PM, Chamness GC. The c-erbB-2 proto-oncogene as a prognostic and predictive marker in breast cancer: a paradigm for the development of other macromolecular markers--a review. Gene. 1995 Jun 14; 159(1):19-27. PMID: 7607568.
      Citations: 61     Fields:    Translation:Humans
    33. Hilsenbeck SG, Chamness GC, Elledge RM, Pujol P. Rising levels of estrogen receptor in breast cancer over 2 decades. Cancer. 1994 Sep 01; 74(5):1601-6. PMID: 8062191.
      Citations: 6     Fields:    Translation:Humans
    34. Elledge RM, Clark GM, Chamness GC, Osborne CK. Tumor biologic factors and breast cancer prognosis among white, Hispanic, and black women in the United States. J Natl Cancer Inst. 1994 May 04; 86(9):705-12. PMID: 7908990.
      Citations: 122     Fields:    Translation:HumansCells
    35. Ravdin PM, Tandon AK, Allred DC, Clark GM, Fuqua SA, Hilsenbeck SH, Chamness GC, Osborne CK. Cathepsin D by western blotting and immunohistochemistry: failure to confirm correlations with prognosis in node-negative breast cancer. J Clin Oncol. 1994 Mar; 12(3):467-74. PMID: 8120545.
      Citations: 7     Fields:    Translation:Humans
    36. Osborne CK, Chamness GC. Translational research in the San Antonio breast cancer SPORE. Breast Cancer Res Treat. 1994; 32(1):1-4. PMID: 7819578.
      Citations: 2     Fields:    Translation:Humans
    37. Fuqua SA, Benedix MG, Krieg S, Weng CN, Chamness GC, Oesterreich S. Constitutive overexpression of the 27,000 dalton heat shock protein in late passage human breast cancer cells. Breast Cancer Res Treat. 1994; 32(2):177-86. PMID: 7865847.
      Citations: 3     Fields:    Translation:HumansCells
    38. Ciocca DR, Oesterreich S, Chamness GC, McGuire WL, Fuqua SA. Biological and clinical implications of heat shock protein 27,000 (Hsp27): a review. J Natl Cancer Inst. 1993 Oct 06; 85(19):1558-70. PMID: 8411230.
      Citations: 101     Fields:    Translation:HumansAnimals
    39. Allred DC, Clark GM, Elledge R, Fuqua SA, Brown RW, Chamness GC, Osborne CK, McGuire WL. Association of p53 protein expression with tumor cell proliferation rate and clinical outcome in node-negative breast cancer. J Natl Cancer Inst. 1993 Feb 03; 85(3):200-6. PMID: 8423624.
      Citations: 208     Fields:    Translation:Humans
    40. Fuqua SA, Chamness GC, McGuire WL. Estrogen receptor mutations in breast cancer. J Cell Biochem. 1993 Feb; 51(2):135-9. PMID: 8440747.
      Citations: 21     Fields:    Translation:Humans
    41. Molina R, Ciocca DR, Tandon AK, Allred DC, Clark GM, Chamness GC, Gullick WJ, McGuire WL. Expression of HER-2/neu oncoprotein in human breast cancer: a comparison of immunohistochemical and western blot techniques. Anticancer Res. 1992 Nov-Dec; 12(6B):1965-71. PMID: 1363511.
      Citations: 10     Fields:    Translation:HumansCells
    42. McGuire WL, Tandon AK, Allred DC, Chamness GC, Ravdin PM, Clark GM. Prognosis and treatment decisions in patients with breast cancer without axillary node involvement. Cancer. 1992 Sep 15; 70(6 Suppl):1775-81. PMID: 1355403.
      Citations: 10     Fields:    Translation:HumansCells
    43. McGuire WL, Chamness GC, Fuqua SA. Abnormal estrogen receptor in clinical breast cancer. J Steroid Biochem Mol Biol. 1992 Sep; 43(1-3):243-7. PMID: 1525064.
      Citations: 11     Fields:    
    44. McGuire WL, Chamness GC, Fuqua SA. The importance of normal and abnormal oestrogen receptor in breast cancer. Cancer Surv. 1992; 14:31-40. PMID: 1423328.
      Citations: 2     Fields:    Translation:HumansCells
    45. McGuire WL, Tandon AK, Allred DC, Chamness GC, Ravdin PM, Clark GM. Treatment decisions in axillary node-negative breast cancer patients. J Natl Cancer Inst Monogr. 1992; (11):173-80. PMID: 1627425.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    46. McGuire WL, Chamness GC, Fuqua SA. Abnormal oestrogen receptor in clinical breast cancer. Eur J Cancer. 1992; 28(2-3):309-10. PMID: 1591044.
      Citations:    Fields:    Translation:Humans
    47. McGuire WL, Chamness GC, Fuqua SA. Estrogen receptor variants in clinical breast cancer. Mol Endocrinol. 1991 Nov; 5(11):1571-7. PMID: 1779964.
      Citations: 45     Fields:    Translation:HumansCells
    48. Fuqua SA, Hill SM, Chamness GC, Benedix MG, Greene GL, O'Malley BW, McGuire WL. Progesterone receptor gene restriction fragment length polymorphisms in human breast tumors. J Natl Cancer Inst. 1991 Aug 21; 83(16):1157-60. PMID: 1679459.
      Citations: 4     Fields:    Translation:HumansCells
    49. Salman M, Reddy BR, Delgado P, Stotter PL, Fulcher LC, Chamness GC. 17 alpha-substituted analogs of estradiol for the development of fluorescent estrogen receptor ligands. Steroids. 1991 Jul; 56(7):375-87. PMID: 1780954.
      Citations: 3     Fields:    
    50. Salman M, Chamness GC. A potential radioiodinated ligand for androgen receptor: 7 alpha-methyl-17 alpha-(2'-(E)-iodovinyl)-19-nortestosterone. J Med Chem. 1991 Mar; 34(3):1019-24. PMID: 2002446.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    51. Fuqua SA, Fitzgerald SD, Chamness GC, Tandon AK, McDonnell DP, Nawaz Z, O'Malley BW, McGuire WL. Variant human breast tumor estrogen receptor with constitutive transcriptional activity. Cancer Res. 1991 Jan 01; 51(1):105-9. PMID: 1988075.
      Citations: 80     Fields:    Translation:HumansCells
    52. Falette NS, Fuqua SA, Chamness GC, Cheah MS, Greene GL, McGuire WL. Estrogen receptor gene methylation in human breast tumors. Cancer Res. 1990 Jul 01; 50(13):3974-8. PMID: 2354445.
      Citations: 10     Fields:    Translation:HumansCells
    53. McGuire WL, Tandon AK, Allred DC, Chamness GC, Clark GM. How to use prognostic factors in axillary node-negative breast cancer patients. J Natl Cancer Inst. 1990 Jun 20; 82(12):1006-15. PMID: 2189998.
      Citations: 55     Fields:    Translation:Humans
    54. Tandon AK, Clark GM, Chamness GC, McGuire WL. Association of the 323/A3 surface glycoprotein with tumor characteristics and behavior in human breast cancer. Cancer Res. 1990 Jun 01; 50(11):3317-21. PMID: 2334924.
      Citations: 12     Fields:    Translation:Humans
    55. Tandon AK, Clark GM, Chamness GC, Chirgwin JM, McGuire WL. Cathepsin D and prognosis in breast cancer. N Engl J Med. 1990 Feb 01; 322(5):297-302. PMID: 2296271.
      Citations: 93     Fields:    Translation:Humans
    56. Chamness GC. Progestin action and progesterone receptors in breast cancer. Cancer Res. 1989 Dec 15; 49(24 Pt 1):7176-9. PMID: 2582458.
      Citations:    Fields:    Translation:Humans
    57. Tandon AK, Clark GM, Chamness GC, Ullrich A, McGuire WL. HER-2/neu oncogene protein and prognosis in breast cancer. J Clin Oncol. 1989 Aug; 7(8):1120-8. PMID: 2569032.
      Citations: 130     Fields:    Translation:HumansCells
    58. Salman M, Stotter PL, Chamness GC. 125I-ligand for progesterone receptor: 17 alpha-(6'-iodohex-1'-ynyl)-19-nortestosterone. J Steroid Biochem. 1989 Jul; 33(1):25-31. PMID: 2761264.
      Citations: 1     Fields:    Translation:HumansCells
    59. Hill SM, Fuqua SA, Chamness GC, Greene GL, McGuire WL. Estrogen receptor expression in human breast cancer associated with an estrogen receptor gene restriction fragment length polymorphism. Cancer Res. 1989 Jan 01; 49(1):145-8. PMID: 2562795.
      Citations: 32     Fields:    Translation:HumansCells
    60. Ogasawara Y, Chamness GC, Salman M, McGuire WL, D?az-Chico BN. A 46-kDa antigen associated with estrogen receptor in human breast cancer. J Steroid Biochem. 1988; 30(1-6):315-20. PMID: 3386260.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    61. Hanauske AR, Osborne CK, Chamness GC, Clark GM, Forseth BJ, Buchok JB, Arteaga CL, Von Hoff DD. Alteration of EGF-receptor binding in human breast cancer cells by antineoplastic agents. Eur J Cancer Clin Oncol. 1987 May; 23(5):545-51. PMID: 3498632.
      Citations: 6     Fields:    Translation:HumansCells
    62. Salman M, Ruiz AA, Stotter PL, Chamness GC. A progesterone receptor affinity chromatography reagent: 17 alpha-hexynyl nortestosterone sepharose. J Steroid Biochem. 1987 Mar; 26(3):383-91. PMID: 3586653.
      Citations:    Fields:    Translation:HumansAnimalsCells
    63. Tandon AK, Chamness GC, McGuire WL. Direct counting of tritium by dissolving Microelisa wells in scintillation fluid. J Immunol Methods. 1986 Sep 27; 92(2):281-3. PMID: 3760588.
      Citations:    Fields:    
    64. Tandon AK, Chamness GC, McGuire WL. Estrogen receptor in very small breast tumor specimens: a modified charcoal-gelatin assay. Cancer Res. 1986 Jul; 46(7):3375-7. PMID: 3708571.
      Citations: 2     Fields:    Translation:HumansCells
    65. Tandon AK, Chamness GC, McGuire WL. Progesterone receptor assays in low-protein cytosols: a modified charcoal-gelatin procedure. J Steroid Biochem. 1986 Jun; 24(6):1135-40. PMID: 2426518.
      Citations: 4     Fields:    Translation:HumansCells
    66. Ray S, Salman M, Ruiz AA, Stotter PL, Chamness GC. Androgen receptor affinity chromatography: synthesis and properties of 17 alpha-epoxypropyl-dihydrotestosterone Sepharose. J Steroid Biochem. 1986 Jun; 24(6):1111-5. PMID: 3736037.
      Citations:    Fields:    Translation:AnimalsCells
    67. Salman M, Reddy BR, Ray S, Stotter PL, Chamness GC. 17 alpha-allyl estradiol analogues as candidates for development of high-affinity fluorescein-estradiol conjugates. J Steroid Biochem. 1986 Feb; 24(2):539-48. PMID: 3702438.
      Citations: 1     Fields:    Translation:AnimalsCells
    68. Gross GE, Clark GM, Chamness GC, McGuire WL. Multiple progesterone receptor assays in human breast cancer. Cancer Res. 1984 Feb; 44(2):836-40. PMID: 6692382.
      Citations: 20     Fields:    Translation:Humans
    69. Ciocca DR, Adams DJ, Bjercke RJ, Sledge GW, Edwards DP, Chamness GC, McGuire WL. Monoclonal antibody storage conditions, and concentration effects on immunohistochemical specificity. J Histochem Cytochem. 1983 May; 31(5):691-6. PMID: 6341459.
      Citations: 13     Fields:    Translation:Animals
    70. Carrillo AJ, Steger RW, Chamness GC. Dopaminergic stimulation of pituitary but not hypothalamic estrogen receptors in ovariectomized rats. Endocrinology. 1983 May; 112(5):1839-46. PMID: 6131816.
      Citations: 3     Fields:    Translation:Animals
    71. Amador AG, Bartke A, Parkening TA, Chamness GC. Genetic differences in androgen receptors and in autoregulation of testicular human chorionic gonadotropin binding sites in the mouse. J Recept Res. 1983; 3(4):495-512. PMID: 6417328.
      Citations:    Fields:    Translation:AnimalsCells
    72. Hull DF, Clark GM, Osborne CK, Chamness GC, Knight WA, McGuire WL. Multiple estrogen receptor assays in human breast cancer. Cancer Res. 1983 Jan; 43(1):413-6. PMID: 6847780.
      Citations: 44     Fields:    Translation:Humans
    73. Chamness GC, McGuire WL. Questions about histochemical methods for steroid receptors. Arch Pathol Lab Med. 1982 Feb; 106(2):53-4. PMID: 6895825.
      Citations: 6     Fields:    Translation:Humans
    74. Mercer WD, Edwards DP, Chamness GC, McGuire WL. Failure of estradiol immunofluorescence in MCF-7 breast cancer cells to detect estrogen receptors. Cancer Res. 1981 Nov; 41(11 Pt 1):4644-52. PMID: 7030480.
      Citations: 3     Fields:    Translation:HumansCells
    75. Chamness GC, Mercer WD, McGuire WL. Are histochemical methods for estrogen receptor valid? J Histochem Cytochem. 1980 Aug; 28(8):792-8. PMID: 7003005.
      Citations: 28     Fields:    Translation:Humans
    76. Edwards DP, Martin PM, Horwitz KB, Chamness GC, McGuire WL. Subcellular compartmentalization of estrogen receptors in human breast cancer cells. Exp Cell Res. 1980 May; 127(1):197-213. PMID: 7379864.
      Citations: 4     Fields:    Translation:HumansCells
    77. Chamness GC, Asch RH, Pauerstein CJ. Danazol binding and translocation of steroid receptors. Am J Obstet Gynecol. 1980 Feb 15; 136(4):426-9. PMID: 7355922.
      Citations: 5     Fields:    Translation:AnimalsCells
    78. Edwards DP, Chamness GC, McGuire WL. Estrogen and progesterone receptor proteins in breast cancer. Biochim Biophys Acta. 1979 Dec 19; 560(4):457-86. PMID: 391286.
      Citations: 17     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    79. Chamness GC, Bannayan GA, Landry LA, Sheridan PJ, McGuire WL. Abnormal reproductive development in rats after neonatally administered antiestrogen (tamoxifen). Biol Reprod. 1979 Dec; 21(5):1087-90. PMID: 574777.
      Citations: 6     Fields:    Translation:Animals
    80. Powell B, Garola RE, Chamness GC, McGuire WL. Measurement of progesterone receptor in human breast cancer biopsies. Cancer Res. 1979 May; 39(5):1678-82. PMID: 427805.
      Citations: 11     Fields:    Translation:HumansCells
    81. Chamness GC, King TW, Sheridan PJ. Androgen receptor in the rat brain--assays and properties. Brain Res. 1979 Feb 02; 161(2):267-76. PMID: 758974.
      Citations: 1     Fields:    Translation:AnimalsCells
    82. McGuire WL, Zava DT, Horwitz KB, Garola RE, Chamness GC. Receptors and breast cancer: do we know it all? J Steroid Biochem. 1978 May; 9(5):461-6. PMID: 682638.
      Citations: 3     Fields:    Translation:HumansCells
    83. Chamness GC, Zava DT, McGuire WL. Methods for assessing the binding of steroid hormones in nuclei. Methods Cell Biol. 1978; 17:325-38. PMID: 212668.
      Citations:    Fields:    Translation:Cells
    84. Koseki Y, Zava DT, Chamness GC, McGuire WL. Estrogen receptor translocation and replenishment by the antiestrogen tamoxifen. Endocrinology. 1977 Oct; 101(4):1104-10. PMID: 561688.
      Citations: 10     Fields:    Translation:AnimalsCells
    85. Koseki Y, Zava DT, Chamness GC, McGuire WL. Progesterone interaction with estrogen and antiestrogen in the rat uterus--receptor effects. Steroids. 1977 Aug; 30(2):169-77. PMID: 201053.
      Citations: 6     Fields:    Translation:AnimalsCells
    86. Zava DT, Chamness GC, Horwitz KB, McGuire WL. Human breast cancer: biologically active estrogen receptor in the absence of estrogen? Science. 1977 May 06; 196(4290):663-4. PMID: 193182.
      Citations: 15     Fields:    Translation:Cells
    87. McGuire WL, De La Garza M, Chamness GC. Evaluation of estrogen receptor assays in human breast cancer tissue. Cancer Res. 1977 Mar; 37(3):637-9. PMID: 837364.
      Citations: 45     Fields:    Translation:Humans
    88. McGuire WL, Chamness GC, Horwitz KB, Zava DT. Prolactin and estrogen receptors in breast cancer. Pathobiol Annu. 1977; 7:191-211. PMID: 201904.
      Citations:    Fields:    Translation:HumansAnimals
    89. McGuire WL, Horwitz KB, Chamness GC, Zava DT. A physiological role for estrogen and progesterone in breast cancer. J Steroid Biochem. 1976 Nov-Dec; 7(11-12):875-82. PMID: 799735.
      Citations: 7     Fields:    Translation:HumansAnimals
    90. Chamness GC, McGuire WL. Scatchard plots: common errors in correction and interpretation. Steroids. 1975 Oct; 26(4):538-42. PMID: 173047.
      Citations: 40     Fields:    Translation:Cells
    91. Chamness GC, Costlow ME, McGuire WL. Estrogen receptor in rat liver and its dependence on prolactin. Steroids. 1975 Sep; 26(3):363-71. PMID: 173045.
      Citations: 22     Fields:    Translation:AnimalsCells
    92. Chamness GC, Huff K, McGuire WL. Protamine-precipitated estrogen receptor: a solid-phase ligand exchange assay. Steroids. 1975 May; 25(5):627-35. PMID: 167479.
      Citations: 9     Fields:    Translation:AnimalsCells
    93. McGuire WL, Chamness GC, Costlow ME, Richert NJ. Steroids and human breast cancer. J Steroid Biochem. 1975 May; 6(5):723-7. PMID: 171510.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    94. Chamness GC, McGuire WL. Extraction artifacts in the preparation of estrogen receptor. Methods Enzymol. 1975; 36:176-87. PMID: 162978.
      Citations:    Fields:    Translation:AnimalsCells
    95. Chamness GC, Jennings AW, McGuire WL. Estrogen receptor binding to isolated nuclei. A nonsaturable process. Biochemistry. 1974 Jan 15; 13(2):327-31. PMID: 4358942.
      Citations: 11     Fields:    Translation:AnimalsCells
    96. McGuire WL, Chamness GC, Costlow ME, Shepherd RE. Hormone dependence in breast cancer. Metabolism. 1974 Jan; 23(1):75-100. PMID: 4357247.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    97. McGuire WL, DeLaGarza M, Chamness GC. Estrogen receptor in a prolactin secreting pituitary tumor (MtTW5). Endocrinology. 1973 Oct; 93(4):810-3. PMID: 4353853.
      Citations: 3     Fields:    Translation:AnimalsCells
    98. Chamness GC, Jennings AW, McGuire WL. Oestrogen receptor binding is not restricted to target nuclei. Nature. 1973 Feb 16; 241(5390):458-60. PMID: 4350283.
      Citations: 3     Fields:    Translation:AnimalsCells
    99. McGuire WL, Chamness GC. Studies on the estrogen receptor in breast cancer. Adv Exp Med Biol. 1973; 36(0):113-36. PMID: 4369235.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    100. McGuire WL, Huff K, Chamness GC. Temperature-dependent binding of estrogen receptor to chromatin. Biochemistry. 1972 Nov 21; 11(24):4562-5. PMID: 4347385.
      Citations: 2     Fields:    Translation:AnimalsCells
    101. Chamness GC, McGuire WL. Estrogen receptor in the rat uterus. Physiological forms and artifacts. Biochemistry. 1972 Jun 20; 11(13):2466-72. PMID: 5040652.
      Citations: 6     Fields:    Translation:AnimalsCells
    102. McGuire WL, Huff K, Jenning A, Chamness GC. Mammary carcinoma: a specific biochemical defect in autonomous tumors. Science. 1972 Jan 21; 175(4019):335-6. PMID: 5008163.
      Citations: 3     Fields:    Translation:AnimalsCells
    103. McGuire WL, Julian JA, Chamness GC. A dissociation between ovarian dependent growth and estrogen sensitivity in mammary carcinoma. Endocrinology. 1971 Oct; 89(4):969-73. PMID: 5092660.
      Citations: 4     Fields:    Translation:AnimalsCells
    104. Chamness GC, Willson CD. An unusual lac repressor mutant. J Mol Biol. 1970 Nov 14; 53(3):561-5. PMID: 4924012.
      Citations: 7     Fields:    Translation:Cells
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