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MUSTAFA F. LOKHANDWALA

TitleProfessor
InstitutionUniversity of Houston College of Pharmacy
DepartmentPharmacological & Pharmaceutical Sciences
AddressHealth 2 4849 Calhoun Road, Room 6007E
Houston, TX 77204-5039
Houston TX 77204-5039
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    Collapse Research 
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    R15AG057024     (LOKHANDWALA, MUSTAFA F.)Aug 1, 2018 - Jul 31, 2021
    NIH
    Role of Nrf2 in aging kidney function
    Role: Principal Investigator
    R01HL139808     (LOKHANDWALA, MUSTAFA F.)Jun 1, 2018 - Feb 28, 2022
    NIH
    Renal Dopamine D1 Receptor Function during Oxidative Stress-related Hypertension
    Role: Principal Investigator
    R01DK098509     (LOKHANDWALA, MUSTAFA F.)Jul 1, 2013 - Sep 30, 2018
    NIH
    Transcriptional regulation of renal dopamine D1 receptors in hypertension during
    Role: Principal Investigator
    R01AG025056     (LOKHANDWALA, MUSTAFA F.)Aug 1, 2005 - Jul 31, 2011
    NIH
    Age-Related Changes in Renal Dopamine Receptor Function
    Role: Principal Investigator
    R01DK058743     (LOKHANDWALA, MUSTAFA F.)Mar 1, 2001 - Jan 31, 2006
    NIH
    RENAL DOPAMINE RECEPTOR FUNCTION IN OBESE ZUCKER RATS
    Role: Principal Investigator
    R01AG015031     (LOKHANDWALA, MUSTAFA F.)Jul 1, 1998 - Dec 31, 2004
    NIH
    KIDNEY DOPAMINE RECEPTOR FUNCTION IN AGED
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mohammad RS, Lokhandwala MF, Banday AA. Age-Related Mitochondrial Impairment and Renal Injury Is Ameliorated by Sulforaphane via Activation of Transcription Factor NRF2. Antioxidants (Basel). 2022 Jan 14; 11(1). PMID: 35052660; PMCID: PMC8772968.
      Citations: 1     
    2. Farooqui Z, Mohammad RS, Lokhandwala MF, Banday AA. Nrf2 inhibition induces oxidative stress, renal inflammation and hypertension in mice. Clin Exp Hypertens. 2021 Feb 17; 43(2):175-180. PMID: 33070655; PMCID: PMC7790982.
      Citations: 13     Fields:    Translation:Animals
    3. Pokkunuri ID, Lokhandwala MF, Banday AA. Protein disulfide isomerase inhibition impairs Keap1/Nrf2 signaling and mitochondrial function and induces apoptosis in renal proximal tubular cells. Am J Physiol Renal Physiol. 2020 10 01; 319(4):F686-F696. PMID: 32830535; PMCID: PMC7642888.
      Citations: 1     Fields:    Translation:HumansCells
    4. Banday AA, Lokhandwala MF. Renal Dopamine Oxidation and Inflammation in High Salt Fed Rats. J Am Heart Assoc. 2020 01 07; 9(1):e014977. PMID: 31880979; PMCID: PMC6988144.
      Citations: 6     Fields:    Translation:AnimalsCells
    5. Banday AA, Diaz AD, Lokhandwala M. Kidney dopamine D1-like receptors and angiotensin 1-7 interaction inhibits renal Na+ transporters. Am J Physiol Renal Physiol. 2019 10 01; 317(4):F949-F956. PMID: 31411069; PMCID: PMC6843046.
      Citations: 7     Fields:    Translation:Animals
    6. Banday AA, Lokhandwala MF. Oxidative stress impairs cGMP-dependent protein kinase activation and vasodilator-stimulated phosphoprotein serine-phosphorylation. Clin Exp Hypertens. 2019; 41(1):5-13. PMID: 29424564; PMCID: PMC7751807.
      Citations: 3     Fields:    Translation:AnimalsCells
    7. Javkhedkar AA, Vaziri ND, Lokhandwala MF, Banday AA, Quiroz Y, Rodriguez-Iturbe B. Resveratrol restored Nrf2 function, reduced renal inflammation, and mitigated hypertension in spontaneously hypertensive rats. Am J Physiol Regul Integr Comp Physiol. 2015 May 15; 308(10):R840-6. PMID: 25761698; PMCID: PMC4459926.
      Citations: 32     Fields:    Translation:Animals
    8. Banday AA, Lokhandwala MF. Transcriptional regulation of renal dopamine D1 receptor function during oxidative stress. Hypertension. 2015 May; 65(5):1064-72. PMID: 25733244; PMCID: PMC4393374.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    9. Bhatt SR, Lokhandwala MF, Banday AA. Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B. Clin Exp Hypertens. 2014; 36(6):367-73. PMID: 25198883; PMCID: PMC4445646.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    10. Banday AA, Lokhandwala MF. Novel gastro-renal axis and sodium regulation during hypertension. Hypertension. 2013 Nov; 62(5):834-5. PMID: 24019398.
      Citations: 4     Fields:    Translation:Animals
    11. Banday AA, Lokhandwala MF. Transcription factor Nrf2 protects renal dopamine D1 receptor function during oxidative stress. Hypertension. 2013 Sep; 62(3):512-7. PMID: 23876469.
      Citations: 10     Fields:    Translation:Animals
    12. Chugh G, Lokhandwala MF, Asghar M. Altered functioning of both renal dopamine D1 and angiotensin II type 1 receptors causes hypertension in old rats. Hypertension. 2012 May; 59(5):1029-36. PMID: 22411927; PMCID: PMC3331925.
      Citations: 31     Fields:    Translation:AnimalsCells
    13. George LE, Lokhandwala MF, Asghar M. Novel role of NF-?B-p65 in antioxidant homeostasis in human kidney-2 cells. Am J Physiol Renal Physiol. 2012 Jun 01; 302(11):F1440-6. PMID: 22397926; PMCID: PMC3378177.
      Citations: 13     Fields:    Translation:HumansCells
    14. Javkhedkar AA, Lokhandwala MF, Banday AA. Defective nitric oxide production impairs angiotensin II-induced Na-K-ATPase regulation in spontaneously hypertensive rats. Am J Physiol Renal Physiol. 2012 Jan 01; 302(1):F47-51. PMID: 21900450.
      Citations: 11     Fields:    Translation:Animals
    15. Asghar M, Tayebati SK, Lokhandwala MF, Hussain T. Potential dopamine-1 receptor stimulation in hypertension management. Curr Hypertens Rep. 2011 Aug; 13(4):294-302. PMID: 21633929.
      Citations: 20     Fields:    Translation:Humans
    16. Bhatt SR, Lokhandwala MF, Banday AA. Resveratrol prevents endothelial nitric oxide synthase uncoupling and attenuates development of hypertension in spontaneously hypertensive rats. Eur J Pharmacol. 2011 Sep 30; 667(1-3):258-64. PMID: 21640096.
      Citations: 56     Fields:    Translation:Animals
    17. Banday AA, Lokhandwala MF. Angiotensin II-mediated biphasic regulation of proximal tubular Na+/H+ exchanger 3 is impaired during oxidative stress. Am J Physiol Renal Physiol. 2011 Aug; 301(2):F364-70. PMID: 21593187.
      Citations: 27     Fields:    Translation:AnimalsCells
    18. Banday AA, Lokhandwala MF. Oxidative stress causes renal angiotensin II type 1 receptor upregulation, Na+/H+ exchanger 3 overstimulation, and hypertension. Hypertension. 2011 Mar; 57(3):452-9. PMID: 21282559.
      Citations: 25     Fields:    Translation:AnimalsCells
    19. Chugh G, Lokhandwala MF, Asghar M. Oxidative stress alters renal D1 and AT1 receptor functions and increases blood pressure in old rats. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F133-8. PMID: 20943769; PMCID: PMC3023225.
      Citations: 24     Fields:    Translation:Animals
    20. Muhammad AB, Lokhandwala MF, Banday AA. Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese rats. Am J Physiol Renal Physiol. 2011 Jan; 300(1):F98-104. PMID: 20926629.
      Citations: 8     Fields:    Translation:Animals
    21. Asghar M, Chugh G, Lokhandwala MF. Inflammation compromises renal dopamine D1 receptor function in rats. Am J Physiol Renal Physiol. 2009 Dec; 297(6):F1543-9. PMID: 19794106; PMCID: PMC2801341.
      Citations: 14     Fields:    Translation:AnimalsCells
    22. George L, Lokhandwala MF, Asghar M. Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats. Am J Physiol Renal Physiol. 2009 Nov; 297(5):F1174-80. PMID: 19759268; PMCID: PMC2781333.
      Citations: 23     Fields:    Translation:AnimalsCells
    23. Banday AA, Lokhandwala MF. Inhibition of natriuretic factors increases blood pressure in rats. Am J Physiol Renal Physiol. 2009 Aug; 297(2):F397-402. PMID: 19474184; PMCID: PMC2724257.
      Citations: 4     Fields:    Translation:AnimalsCells
    24. Banday AA, Lokhandwala MF. Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling. Hypertension. 2008 Dec; 52(6):1099-105. PMID: 18955661.
      Citations: 18     Fields:    Translation:AnimalsCells
    25. Asghar M, Chillar A, Lokhandwala MF. Renal proximal tubules from old Fischer 344 rats grow into epithelial cells in cultures and exhibit increased oxidative stress and reduced D1 receptor function. Am J Physiol Cell Physiol. 2008 Nov; 295(5):C1326-31. PMID: 18799649; PMCID: PMC2584979.
      Citations: 11     Fields:    Translation:AnimalsCells
    26. Banday AA, Lokhandwala MF. Dopamine receptors and hypertension. Curr Hypertens Rep. 2008 Aug; 10(4):268-75. PMID: 18625155.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    27. Banday AA, Lokhandwala MF. Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension. Am J Physiol Renal Physiol. 2008 Sep; 295(3):F698-706. PMID: 18614617; PMCID: PMC2536884.
      Citations: 22     Fields:    Translation:AnimalsCells
    28. Banday AA, Lau YS, Lokhandwala MF. Oxidative stress causes renal dopamine D1 receptor dysfunction and salt-sensitive hypertension in Sprague-Dawley rats. Hypertension. 2008 Feb; 51(2):367-75. PMID: 18158345.
      Citations: 35     Fields:    Translation:AnimalsCells
    29. Asghar M, George L, Lokhandwala MF. Exercise decreases oxidative stress and inflammation and restores renal dopamine D1 receptor function in old rats. Am J Physiol Renal Physiol. 2007 Sep; 293(3):F914-9. PMID: 17634393.
      Citations: 45     Fields:    Translation:Animals
    30. Banday AA, Fazili FR, Lokhandwala MF. Insulin causes renal dopamine D1 receptor desensitization via GRK2-mediated receptor phosphorylation involving phosphatidylinositol 3-kinase and protein kinase C. Am J Physiol Renal Physiol. 2007 Sep; 293(3):F877-84. PMID: 17567939.
      Citations: 18     Fields:    Translation:AnimalsCells
    31. Banday AA, Lokhandwala MF. Oxidative stress reduces renal dopamine D1 receptor-Gq/11alpha G protein-phospholipase C signaling involving G protein-coupled receptor kinase 2. Am J Physiol Renal Physiol. 2007 Jul; 293(1):F306-15. PMID: 17459951.
      Citations: 22     Fields:    Translation:AnimalsCells
    32. Banday AA, Fazili FR, Lokhandwala MF. Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kappaB and protein kinase C. J Am Soc Nephrol. 2007 May; 18(5):1446-57. PMID: 17409305.
      Citations: 34     Fields:    Translation:AnimalsCells
    33. Banday AA, Muhammad AB, Fazili FR, Lokhandwala M. Mechanisms of oxidative stress-induced increase in salt sensitivity and development of hypertension in Sprague-Dawley rats. Hypertension. 2007 Mar; 49(3):664-71. PMID: 17200436.
      Citations: 16     Fields:    Translation:AnimalsCells
    34. Fardoun RZ, Asghar M, Lokhandwala M. Role of nuclear factor kappa B (NF-kappaB) in oxidative stress-induced defective dopamine D1 receptor signaling in the renal proximal tubules of Sprague-Dawley rats. Free Radic Biol Med. 2007 Mar 15; 42(6):756-64. PMID: 17320758; PMCID: PMC2696818.
      Citations: 9     Fields:    Translation:AnimalsCells
    35. Fardoun RZ, Asghar M, Lokhandwala M. Role of oxidative stress in defective renal dopamine D1 receptor-G protein coupling and function in old Fischer 344 rats. Am J Physiol Renal Physiol. 2006 Nov; 291(5):F945-51. PMID: 16757732.
      Citations: 21     Fields:    Translation:AnimalsCells
    36. Marwaha A, Lokhandwala MF. Tempol reduces oxidative stress and restores renal dopamine D1-like receptor- G protein coupling and function in hyperglycemic rats. Am J Physiol Renal Physiol. 2006 Jul; 291(1):F58-66. PMID: 16478977.
      Citations: 17     Fields:    Translation:AnimalsCells
    37. Asghar M, Banday AA, Fardoun RZ, Lokhandwala MF. Hydrogen peroxide causes uncoupling of dopamine D1-like receptors from G proteins via a mechanism involving protein kinase C and G-protein-coupled receptor kinase 2. Free Radic Biol Med. 2006 Jan 01; 40(1):13-20. PMID: 16337875.
      Citations: 25     Fields:    Translation:AnimalsCells
    38. Banday AA, Marwaha A, Tallam LS, Lokhandwala MF. Tempol reduces oxidative stress, improves insulin sensitivity, decreases renal dopamine D1 receptor hyperphosphorylation, and restores D1 receptor-G-protein coupling and function in obese Zucker rats. Diabetes. 2005 Jul; 54(7):2219-26. PMID: 15983225.
      Citations: 44     Fields:    Translation:AnimalsCells
    39. Banday AA, Hussain T, Lokhandwala MF. Renal dopamine D(1) receptor dysfunction is acquired and not inherited in obese Zucker rats. Am J Physiol Renal Physiol. 2004 Jul; 287(1):F109-16. PMID: 15068975.
      Citations: 10     Fields:    Translation:Animals
    40. Trivedi M, Marwaha A, Lokhandwala M. Rosiglitazone restores G-protein coupling, recruitment, and function of renal dopamine D1A receptor in obese Zucker rats. Hypertension. 2004 Feb; 43(2):376-82. PMID: 14718363.
      Citations: 8     Fields:    Translation:AnimalsCells
    41. Marwaha A, Banday AA, Lokhandwala MF. Reduced renal dopamine D1 receptor function in streptozotocin-induced diabetic rats. Am J Physiol Renal Physiol. 2004 Mar; 286(3):F451-7. PMID: 14612382.
      Citations: 27     Fields:    Translation:Animals
    42. Marwaha A, Lokhandwala MF. Diminished natriuretic response to dopamine D1 receptor agonist, SKF-38393 in obese Zucker rats. Clin Exp Hypertens. 2003 Nov; 25(8):509-15. PMID: 14649308.
      Citations: 8     Fields:    Translation:Animals
    43. Asghar M, Hussain T, Lokhandwala MF. Overexpression of PKC-betaI and -delta contributes to higher PKC activity in the proximal tubules of old Fischer 344 rats. Am J Physiol Renal Physiol. 2003 Dec; 285(6):F1100-7. PMID: 12904329.
      Citations: 7     Fields:    Translation:Animals
    44. Banday AA, Asghar M, Hussain T, Lokhandwala MF. Dopamine-mediated inhibition of renal Na,K-ATPase is reduced by insulin. Hypertension. 2003 Jun; 41(6):1353-8. PMID: 12707290.
      Citations: 14     Fields:    Translation:AnimalsCells
    45. Umrani DN, Banday AA, Hussain T, Lokhandwala MF. Rosiglitazone treatment restores renal dopamine receptor function in obese Zucker rats. Hypertension. 2002 Dec; 40(6):880-5. PMID: 12468573.
      Citations: 13     Fields:    Translation:AnimalsCells
    46. Asghar M, Hussain T, Lokhandwala MF. Higher basal serine phosphorylation of D1A receptors in proximal tubules of old Fischer 344 rats. Am J Physiol Renal Physiol. 2002 Aug; 283(2):F350-5. PMID: 12110520.
      Citations: 9     Fields:    Translation:AnimalsCells
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