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PETER JOHN ARWYN DAVIES

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
DivisionPharmacology
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    R01AM027078     (DAVIES, PETER J)Apr 1, 1980 - Jun 30, 1987
    NIH/NIADDK
    THE ROLE OF TRANSGLUTAMINASE IN HORMONE INTERNALIZATION
    Role: Principal Investigator

    R01DK027078     (DAVIES, PETER J)Apr 1, 1980 - Jun 30, 1993
    NIH/NIDDK
    ROLE OF TRANSGLUTAMINASE IN HORMONE INTERNALIZATION
    Role: Principal Investigator

    R13CA052416     (DAVIES, PETER J)Apr 6, 1990 - Mar 31, 1991
    NIH/NCI
    FASEB SUMMER RESEARCH CONFERENCE ON RETINOIDS
    Role: Principal Investigator

    R13CA056489     (DAVIES, PETER J)May 15, 1992 - May 14, 1993
    NIH/NCI
    FASEB SUMMER RESEARCH CONFERENCE ON RETINOIDS
    Role: Principal Investigator

    R01HD034896     (DAVIES, PETER J)Sep 1, 1997 - Aug 31, 2000
    NIH/NICHD
    MECHANISMS OF RETINOID ACTION IN THE UTERUS
    Role: Principal Investigator

    R01CA076088     (DAVIES, PETER J)Jul 1, 1998 - Apr 30, 2003
    NIH/NCI
    RETINOID REGULATION OF TRANSGLUTAMINASE GENE EXPRESSION
    Role: Principal Investigator

    S10RR013924     (DAVIES, PETER J)Apr 15, 1999 - Apr 14, 2000
    NIH/NCRR
    7700 SEQUENCE DETECTOR AND BIOMEK WORKSTATION
    Role: Principal Investigator

    R03TW001146     (DAVIES, PETER J)Sep 30, 1999 - Aug 31, 2003
    NIH/FIC
    CHROMATIN ACTIVATION IN RETINOID-INDUCED APOPTOSIS
    Role: Principal Investigator

    R01DK060045     (DAVIES, PETER J)Sep 1, 2001 - Aug 31, 2006
    NIH/NIDDK
    Rexinoid-Regulated Muscle Gene Expression
    Role: Principal Investigator

    C06RR017163     (DAVIES, PETER J)Sep 19, 2001 - Sep 30, 2006
    NIH/NCRR
    EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    Role: Principal Investigator

    C06RR017344     (DAVIES, PETER J)Jun 1, 2002 - Jun 30, 2007
    NIH/NCRR
    CONSTRUCTION OF ANIMAL FACILITY
    Role: Principal Investigator

    S07RR018166     (DAVIES, PETER J)Sep 1, 2002 - Aug 31, 2005
    NIH/NCRR
    Support for the Human Subjects Protection Program at UTH
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Vijay GV, Zhao N, Den Hollander P, Toneff MJ, Joseph R, Pietila M, Taube JH, Sarkar TR, Ramirez-Pena E, Werden SJ, Shariati M, Gao R, Sobieski M, Stephan CC, Sphyris N, Miura N, Davies P, Chang JT, Soundararajan R, Rosen JM, Mani SA. GSK3ß regulates epithelial-mesenchymal transition and cancer stem cell properties in triple-negative breast cancer. Breast Cancer Res. 2019 03 07; 21(1):37. PMID: 30845991.
      View in: PubMed
    2. Huang L, Brunell D, Stephan C, Mancuso J, He B, Thompson TC, Zinner R, Kim J, Davies P, Wong STC. Driver Network as a Biomarker: Systematic integration and network modeling of multi-omics data to derive driver signaling pathways for drug combination prediction. Bioinformatics. 2019 Feb 15. PMID: 30768150.
      View in: PubMed
    3. Chowdhury P, Powell RT, Stephan C, Uray IP, Talley T, Karki M, Tripathi DN, Park YS, Mancini MA, Davies P, Dere R. Bexarotene - a novel modulator of AURKA and the primary cilium in VHL-deficient cells. J Cell Sci. 2018 Dec 14; 131(24). PMID: 30518623.
      View in: PubMed
    4. Tassoni A, Zappi A, Melucci D, Reisch BI, Davies PJ. Seasonal changes in amino acids and phenolic compounds in fruits from hybrid cross populations of American grapes differing in disease resistance. Plant Physiol Biochem. 2019 Feb; 135:182-193. PMID: 30554065.
      View in: PubMed
    5. Zhou X, Taylor MP, Davies PJ. Tracing natural and industrial contamination and lead isotopic compositions in an Australian native bee species. Environ Pollut. 2018 Nov; 242(Pt A):54-62. PMID: 29960253.
      View in: PubMed
    6. McGrail DJ, Lin CC, Dai H, Mo W, Li Y, Stephan C, Davies P, Lu Z, Mills GB, Lee JS, Lin SY. Defective Replication Stress Response Is Inherently Linked to the Cancer Stem Cell Phenotype. Cell Rep. 2018 05 15; 23(7):2095-2106. PMID: 29768207.
      View in: PubMed
    7. Davies PJ. Reflections from the Janus face of gibberellin in legume nodulation. J Exp Bot. 2018 04 09; 69(8):1824-1828. PMID: 29635483.
      View in: PubMed
    8. Zhou X, Taylor MP, Davies PJ, Prasad S. Identifying Sources of Environmental Contamination in European Honey Bees (Apis mellifera) Using Trace Elements and Lead Isotopic Compositions. Environ Sci Technol. 2018 02 06; 52(3):991-1001. PMID: 29249154.
      View in: PubMed
    9. Ali AE, Strezov V, Davies PJ, Wright I. River sediment quality assessment using sediment quality indices for the Sydney basin, Australia affected by coal and coal seam gas mining. Sci Total Environ. 2018 Mar; 616-617:695-702. PMID: 29111250.
      View in: PubMed
    10. Merani R, Davies P. Reply. Ophthalmology. 2017 07; 124(7):e58. PMID: 28645345.
      View in: PubMed
    11. Tamas IA, Davies PJ. Dynamics and control of phloem loading of indole-3-acetic acid in seedling cotyledons of Ricinus communis. J Exp Bot. 2016 08; 67(15):4755-65. PMID: 27371947.
      View in: PubMed
    12. Sottejeau Y, Bretteville A, Cantrelle FX, Malmanche N, Demiaute F, Mendes T, Delay C, Alves Dos Alves H, Flaig A, Davies P, Dourlen P, Dermaut B, Laporte J, Amouyel P, Lippens G, Chapuis J, Landrieu I, Lambert JC. Tau phosphorylation regulates the interaction between BIN1's SH3 domain and Tau's proline-rich domain. Acta Neuropathol Commun. 2015 Sep 23; 3:58. PMID: 26395440.
      View in: PubMed
    13. Davies PJ, Gore DB, Khan SJ. Managing produced water from coal seam gas projects: implications for an emerging industry in Australia. Environ Sci Pollut Res Int. 2015 Jul; 22(14):10981-1000. PMID: 25783163.
      View in: PubMed
    14. Koppel J, Vingtdeux V, Marambaud P, d'Abramo C, Jimenez H, Stauber M, Friedman R, Davies P. CB2 receptor deficiency increases amyloid pathology and alters tau processing in a transgenic mouse model of Alzheimer's disease. Mol Med. 2013 Nov 08; 19:357-64. PMID: 24408112.
      View in: PubMed
    15. Forest SK, Acker CM, d'Abramo C, Davies P. Methods for measuring tau pathology in transgenic mouse models. J Alzheimers Dis. 2013; 33(2):463-71. PMID: 22976073.
      View in: PubMed
    16. Cohen T, Widdows D, Schvaneveldt RW, Davies P, Rindflesch TC. Discovering discovery patterns with Predication-based Semantic Indexing. J Biomed Inform. 2012 Dec; 45(6):1049-65. PMID: 22841748.
      View in: PubMed
    17. Cochand NJ, Wild M, Brugniaux JV, Davies PJ, Evans KA, Wise RG, Bailey DM. Sea-level assessment of dynamic cerebral autoregulation predicts susceptibility to acute mountain sickness at high altitude. Stroke. 2011 Dec; 42(12):3628-30. PMID: 21960569.
      View in: PubMed
    18. Taylor MP, Ives CD, Davies PJ, Stokes R. Troubled waters-an examination of the disconnect between river science and law. Environ Sci Technol. 2011 Oct 01; 45(19):8178-9. PMID: 21902280.
      View in: PubMed
    19. Boutajangout A, Ingadottir J, Davies P, Sigurdsson EM. Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain. J Neurochem. 2011 Aug; 118(4):658-67. PMID: 21644996.
      View in: PubMed
    20. Sklensky DE, Davies PJ. Resource partitioning to male and female flowers of Spinacia oleracea L. in relation to whole-plant monocarpic senescence. J Exp Bot. 2011 Aug; 62(12):4323-36. PMID: 21565983.
      View in: PubMed
    21. Zhang Q, Shen Q, Celestino J, Milam MR, Westin SN, Lacour RA, Meyer LA, Shipley GL, Davies PJ, Deng L, McCampbell AS, Broaddus RR, Lu KH. Enhanced estrogen-induced proliferation in obese rat endometrium. Am J Obstet Gynecol. 2009 Feb; 200(2):186.e1-8. PMID: 19185100.
      View in: PubMed
    22. McCampbell AS, Walker CL, Broaddus RR, Cook JD, Davies PJ. Developmental reprogramming of IGF signaling and susceptibility to endometrial hyperplasia in the rat. Lab Invest. 2008 Jun; 88(6):615-26. PMID: 18427555.
      View in: PubMed
    23. McCampbell AS, Broaddus RR, Loose DS, Davies PJ. Overexpression of the insulin-like growth factor I receptor and activation of the AKT pathway in hyperplastic endometrium. Clin Cancer Res. 2006 Nov 01; 12(21):6373-8. PMID: 17085648.
      View in: PubMed
    24. Tassoni A, Watkins CB, Davies PJ. Inhibition of the ethylene response by 1-MCP in tomato suggests that polyamines are not involved in delaying ripening, but may moderate the rate of ripening or over-ripening. J Exp Bot. 2006; 57(12):3313-25. PMID: 16920766.
      View in: PubMed
    25. Siegel DA, Davies P, Dobrenis K, Huang M. Tomoregulin-2 is found extensively in plaques in Alzheimer's disease brain. J Neurochem. 2006 Jul; 98(1):34-44. PMID: 16805794.
      View in: PubMed
    26. d'Abramo C, Ricciarelli R, Pronzato MA, Davies P. Troglitazone, a peroxisome proliferator-activated receptor-gamma agonist, decreases tau phosphorylation in CHOtau4R cells. J Neurochem. 2006 Aug; 98(4):1068-77. PMID: 16787414.
      View in: PubMed
    27. Deng L, Broaddus RR, McCampbell A, Shipley GL, Loose DS, Stancel GM, Pickar JH, Davies PJ. Identification of a novel estrogen-regulated gene, EIG121, induced by hormone replacement therapy and differentially expressed in type I and type II endometrial cancer. Clin Cancer Res. 2005 Dec 01; 11(23):8258-64. PMID: 16322283.
      View in: PubMed
    28. Balint BL, Szanto A, Madi A, Bauer UM, Gabor P, Benko S, Puskás LG, Davies PJ, Nagy L. Arginine methylation provides epigenetic transcription memory for retinoid-induced differentiation in myeloid cells. Mol Cell Biol. 2005 Jul; 25(13):5648-63. PMID: 15964820.
      View in: PubMed
    29. Tchaikovskaya T, Fraifeld V, Urphanishvili T, Andorfer JH, Davies P, Listowsky I. Glutathione S-transferase hGSTM3 and ageing-associated neurodegeneration: relationship to Alzheimer's disease. Mech Ageing Dev. 2005 Feb; 126(2):309-15. PMID: 15621212.
      View in: PubMed
    30. Szanto A, Narkar V, Shen Q, Uray IP, Davies PJ, Nagy L. Retinoid X receptors: X-ploring their (patho)physiological functions. Cell Death Differ. 2004 Dec; 11 Suppl 2:S126-43. PMID: 15608692.
      View in: PubMed
    31. Yao J, Petanceska SS, Montine TJ, Holtzman DM, Schmidt SD, Parker CA, Callahan MJ, Lipinski WJ, Bisgaier CL, Turner BA, Nixon RA, Martins RN, Ouimet C, Smith JD, Davies P, Laska E, Ehrlich ME, Walker LC, Mathews PM, Gandy S. Aging, gender and APOE isotype modulate metabolism of Alzheimer's Abeta peptides and F-isoprostanes in the absence of detectable amyloid deposits. J Neurochem. 2004 Aug; 90(4):1011-8. PMID: 15287908.
      View in: PubMed
    32. Williams ET, Leyk M, Wrighton SA, Davies PJ, Loose DS, Shipley GL, Strobel HW. Estrogen regulation of the cytochrome P450 3A subfamily in humans. J Pharmacol Exp Ther. 2004 Nov; 311(2):728-35. PMID: 15282264.
      View in: PubMed
    33. Conrad C, Vianna C, Schultz C, Thal DR, Ghebremedhin E, Lenz J, Braak H, Davies P. Molecular evolution and genetics of the Saitohin gene and tau haplotype in Alzheimer's disease and argyrophilic grain disease. J Neurochem. 2004 Apr; 89(1):179-88. PMID: 15030402.
      View in: PubMed
    34. Shen Q, Cline GW, Shulman GI, Leibowitz MD, Davies PJ. Effects of rexinoids on glucose transport and insulin-mediated signaling in skeletal muscles of diabetic (db/db) mice. J Biol Chem. 2004 May 07; 279(19):19721-31. PMID: 14998989.
      View in: PubMed
    35. Bailey CD, Graham RM, Nanda N, Davies PJ, Johnson GV. Validity of mouse models for the study of tissue transglutaminase in neurodegenerative diseases. Mol Cell Neurosci. 2004 Mar; 25(3):493-503. PMID: 15033177.
      View in: PubMed
    36. Andorfer C, Kress Y, Espinoza M, de Silva R, Tucker KL, Barde YA, Duff K, Davies P. Hyperphosphorylation and aggregation of tau in mice expressing normal human tau isoforms. J Neurochem. 2003 Aug; 86(3):582-90. PMID: 12859672.
      View in: PubMed
    37. Xu Y, Gu X, Li J, Li Q, Davies PJ, Zhu Y. Studies on gene structure, enzymatic activity and regulatory mechanism of acetohydroxy acid isomeroreductase from G2 pea. Sci China C Life Sci. 2003 Aug; 46(4):389-98. PMID: 21072611.
      View in: PubMed
    38. Tandon A, Yu H, Wang L, Rogaeva E, Sato C, Chishti MA, Kawarai T, Hasegawa H, Chen F, Davies P, Fraser PE, Westaway D, St George-Hyslop PH. Brain levels of CDK5 activator p25 are not increased in Alzheimer's or other neurodegenerative diseases with neurofibrillary tangles. J Neurochem. 2003 Aug; 86(3):572-81. PMID: 12859671.
      View in: PubMed
    39. Hogg M, Grujic ZM, Baker M, Demirci S, Guillozet AL, Sweet AP, Herzog LL, Weintraub S, Mesulam MM, LaPointe NE, Gamblin TC, Berry RW, Binder LI, de Silva R, Lees A, Espinoza M, Davies P, Grover A, Sahara N, Ishizawa T, Dickson D, Yen SH, Hutton M, Bigio EH. The L266V tau mutation is associated with frontotemporal dementia and Pick-like 3R and 4R tauopathy. Acta Neuropathol. 2003 Oct; 106(4):323-36. PMID: 12883828.
      View in: PubMed
    40. Anakk S, Kalsotra A, Shen Q, Vu MT, Staudinger JL, Davies PJ, Strobel HW. Genomic characterization and regulation of CYP3a13: role of xenobiotics and nuclear receptors. FASEB J. 2003 Sep; 17(12):1736-8. PMID: 12958193.
      View in: PubMed
    41. Thomazy VA, Vega F, Medeiros LJ, Davies PJ, Jones D. Phenotypic modulation of the stromal reticular network in normal and neoplastic lymph nodes: tissue transglutaminase reveals coordinate regulation of multiple cell types. Am J Pathol. 2003 Jul; 163(1):165-74. PMID: 12819021.
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    42. Uray IP, Connelly JH, Frazier OH, Taegtmeyer H, Davies PJ. Mechanical unloading increases caveolin expression in the failing human heart. Cardiovasc Res. 2003 Jul 01; 59(1):57-66. PMID: 12829176.
      View in: PubMed
    43. Rosin FM, Hart JK, Horner HT, Davies PJ, Hannapel DJ. Overexpression of a knotted-like homeobox gene of potato alters vegetative development by decreasing gibberellin accumulation. Plant Physiol. 2003 May; 132(1):106-17. PMID: 12746517.
      View in: PubMed
    44. Deng L, Shipley GL, Loose-Mitchell DS, Stancel GM, Broaddus R, Pickar JH, Davies PJ. Coordinate regulation of the production and signaling of retinoic acid by estrogen in the human endometrium. J Clin Endocrinol Metab. 2003 May; 88(5):2157-63. PMID: 12727970.
      View in: PubMed
    45. Callaerts-Vegh Z, Evans KL, Shipley GL, Davies PJ, Cuba DL, Gurji HA, Giles H, Bond RA. Effects of different beta adrenoceptor ligands in mice with permanent occlusion of the left anterior descending coronary artery. Br J Pharmacol. 2003 Apr; 138(8):1505-16. PMID: 12721106.
      View in: PubMed
    46. Copland JA, Davies PJ, Shipley GL, Wood CG, Luxon BA, Urban RJ. The use of DNA microarrays to assess clinical samples: the transition from bedside to bench to bedside. Recent Prog Horm Res. 2003; 58:25-53. PMID: 12795413.
      View in: PubMed
    47. Ahuja HS, Szanto A, Nagy L, Davies PJ. The retinoid X receptor and its ligands: versatile regulators of metabolic function, cell differentiation and cell death. J Biol Regul Homeost Agents. 2003 Jan-Mar; 17(1):29-45. PMID: 12757020.
      View in: PubMed
    48. Ahuja TS, Gopalani A, Davies P, Ahuja H. Matrix metalloproteinase-9 expression in renal biopsies of patients with HIV-associated nephropathy. Nephron Clin Pract. 2003; 95(3):c100-4. PMID: 14646370.
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    49. Thomázy VA, Luthra R, Uthman MO, Davies PJ, Medeiros LJ. Determination of cyclin D1 and CD20 mRNA levels by real-time quantitative RT-PCR from archival tissue sections of mantle cell lymphoma and other non-Hodgkin's lymphomas. J Mol Diagn. 2002 Nov; 4(4):201-8. PMID: 12411587.
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    50. Uray IP, Connelly JH, Thomázy V, Shipley GL, Vaughn WK, Frazier OH, Taegtmeyer H, Davies PJ. Left ventricular unloading alters receptor tyrosine kinase expression in the failing human heart. J Heart Lung Transplant. 2002 Jul; 21(7):771-82. PMID: 12100903.
      View in: PubMed
    51. Festoff BW, SantaCruz K, Arnold PM, Sebastian CT, Davies PJ, Citron BA. Injury-induced "switch" from GTP-regulated to novel GTP-independent isoform of tissue transglutaminase in the rat spinal cord. J Neurochem. 2002 May; 81(4):708-18. PMID: 12065630.
      View in: PubMed
    52. Razeghi P, Young ME, Ying J, Depre C, Uray IP, Kolesar J, Shipley GL, Moravec CS, Davies PJ, Frazier OH, Taegtmeyer H. Downregulation of metabolic gene expression in failing human heart before and after mechanical unloading. Cardiology. 2002; 97(4):203-9. PMID: 12145475.
      View in: PubMed
    53. Citron BA, Suo Z, SantaCruz K, Davies PJ, Qin F, Festoff BW. Protein crosslinking, tissue transglutaminase, alternative splicing and neurodegeneration. Neurochem Int. 2002 Jan; 40(1):69-78. PMID: 11738473.
      View in: PubMed
    54. Uray IP, Davies PJ, Fésüs L. Pharmacological separation of the expression of tissue transglutaminase and apoptosis after chemotherapeutic treatment of HepG2 cells. Mol Pharmacol. 2001 Jun; 59(6):1388-94. PMID: 11353797.
      View in: PubMed
    55. Singh Ahuja H, Liu S, Crombie DL, Boehm M, Leibowitz MD, Heyman RA, Depre C, Nagy L, Tontonoz P, Davies PJ. Differential effects of rexinoids and thiazolidinediones on metabolic gene expression in diabetic rodents. Mol Pharmacol. 2001 Apr; 59(4):765-73. PMID: 11259621.
      View in: PubMed
    56. Juneja HS, Lee S, Thomazy V, Shipley G, Davies PJ. Acute activation of gp130 gene expression in bone marrow stromal cells by contact with myeloma-derived lymphoblastic cell line ARH77 cell membranes. J Interferon Cytokine Res. 2001 Mar; 21(3):157-66. PMID: 11331038.
      View in: PubMed
    57. Young ME, Patil S, Ying J, Depre C, Ahuja HS, Shipley GL, Stepkowski SM, Davies PJ, Taegtmeyer H. Uncoupling protein 3 transcription is regulated by peroxisome proliferator-activated receptor (alpha) in the adult rodent heart. FASEB J. 2001 Mar; 15(3):833-45. PMID: 11259402.
      View in: PubMed
    58. Davies PJ, Berry SA, Shipley GL, Eckel RH, Hennuyer N, Crombie DL, Ogilvie KM, Peinado-Onsurbe J, Fievet C, Leibowitz MD, Heyman RA, Auwerx J. Metabolic effects of rexinoids: tissue-specific regulation of lipoprotein lipase activity. Mol Pharmacol. 2001 Feb; 59(2):170-6. PMID: 11160850.
      View in: PubMed
    59. Uray IP, Connelly JH, Frazier O, Taegtmeyer H, Davies PJ. Altered expression of tyrosine kinase receptors Her2/neu and GP130 following left ventricular assist device (LVAD) placement in patients with heart failure. J Heart Lung Transplant. 2001 Feb; 20(2):210. PMID: 11250381.
      View in: PubMed
    60. Szegezdi E, Szondy Z, Nagy L, Nemes Z, Friis RR, Davies PJ, Fésüs L. Apoptosis-linked in vivo regulation of the tissue transglutaminase gene promoter. Cell Death Differ. 2000 Dec; 7(12):1225-33. PMID: 11175260.
      View in: PubMed
    61. Citron BA, SantaCruz KS, Davies PJ, Festoff BW. Intron-exon swapping of transglutaminase mRNA and neuronal Tau aggregation in Alzheimer's disease. J Biol Chem. 2001 Feb 02; 276(5):3295-301. PMID: 11013236.
      View in: PubMed
    62. Depre C, Young ME, Ying J, Ahuja HS, Han Q, Garza N, Davies PJ, Taegtmeyer H. Streptozotocin-induced changes in cardiac gene expression in the absence of severe contractile dysfunction. J Mol Cell Cardiol. 2000 Jun; 32(6):985-96. PMID: 10888252.
      View in: PubMed
    63. Depre C, Davies PJ, Taegtmeyer H. Transcriptional adaptation of the heart to mechanical unloading. Am J Cardiol. 1999 Jun 17; 83(12A):58H-63H. PMID: 10750589.
      View in: PubMed
    64. Dupé V, Ghyselinck NB, Thomazy V, Nagy L, Davies PJ, Chambon P, Mark M. Essential roles of retinoic acid signaling in interdigital apoptosis and control of BMP-7 expression in mouse autopods. Dev Biol. 1999 Apr 01; 208(1):30-43. PMID: 10075839.
      View in: PubMed
    65. Thomázy VA, Davies PJ. Expression of tissue transglutaminase in the developing chicken limb is associated both with apoptosis and endochondral ossification. Cell Death Differ. 1999 Feb; 6(2):146-54. PMID: 10200561.
      View in: PubMed
    66. Depre C, Shipley GL, Chen W, Han Q, Doenst T, Moore ML, Stepkowski S, Davies PJ, Taegtmeyer H. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med. 1998 Nov; 4(11):1269-75. PMID: 9809550.
      View in: PubMed
    67. Ritter SJ, Davies PJ. Identification of a transforming growth factor-beta1/bone morphogenetic protein 4 (TGF-beta1/BMP4) response element within the mouse tissue transglutaminase gene promoter. J Biol Chem. 1998 May 22; 273(21):12798-806. PMID: 9582307.
      View in: PubMed
    68. Zhu Y, Zhang Y, Luo J, Davies PJ, Ho DT. PPF-1, a post-floral-specific gene expressed in short-day-grown G2 pea, may be important for its never-senescing phenotype. Gene. 1998 Feb 16; 208(1):1-6. PMID: 9479033.
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    69. Kuncio GS, Tsyganskaya M, Zhu J, Liu SL, Nagy L, Thomazy V, Davies PJ, Zern MA. TNF-alpha modulates expression of the tissue transglutaminase gene in liver cells. Am J Physiol. 1998 02; 274(2):G240-5. PMID: 9486175.
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    70. Nagy L, Thomazy VA, Heyman RA, Davies PJ. Retinoid-induced apoptosis in normal and neoplastic tissues. Cell Death Differ. 1998 Jan; 5(1):11-9. PMID: 10200441.
      View in: PubMed
    71. Nagy L, Thomázy VA, Davies PJ. A transgenic mouse model for the study of apoptosis during limb development. Cell Death Differ. 1998 Jan; 5(1):126. PMID: 10200453.
      View in: PubMed
    72. Simko I, McMurry S, Yang HM, Manschot A, Davies PJ, Ewing EE. Evidence from Polygene Mapping for a Causal Relationship between Potato Tuber Dormancy and Abscisic Acid Content. Plant Physiol. 1997 Dec; 115(4):1453-1459. PMID: 12223876.
      View in: PubMed
    73. Jones RA, Nicholas B, Mian S, Davies PJ, Griffin M. Reduced expression of tissue transglutaminase in a human endothelial cell line leads to changes in cell spreading, cell adhesion and reduced polymerisation of fibronectin. J Cell Sci. 1997 Oct; 110 ( Pt 19):2461-72. PMID: 9410884.
      View in: PubMed
    74. Nagy L, Thomázy VA, Saydak MM, Stein JP, Davies PJ. The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Cell Death Differ. 1997 Oct; 4(7):534-47. PMID: 14555966.
      View in: PubMed
    75. Piredda L, Amendola A, Colizzi V, Davies PJ, Farrace MG, Fraziano M, Gentile V, Uray I, Piacentini M, Fesus L. Lack of 'tissue' transglutaminase protein cross-linking leads to leakage of macromolecules from dying cells: relationship to development of autoimmunity in MRLIpr/Ipr mice. Cell Death Differ. 1997 Aug; 4(6):463-72. PMID: 16465267.
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    76. Balajthy Z, Kedei N, Nagy L, Davies PJ, Fésüs L. Lack of induction of tissue transglutaminase but activation of the preexisting enzyme in c-Myc-induced apoptosis of CHO cells. Biochem Biophys Res Commun. 1997 Jul 18; 236(2):280-4. PMID: 9240425.
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    77. Gentile V, Porta R, Chiosi E, Spina A, Valente F, Pezone R, Davies PJ, Alaadik A, Illiano G. tTGase/G alpha h protein expression inhibits adenylate cyclase activity in Balb-C 3T3 fibroblasts membranes. Biochim Biophys Acta. 1997 Jun 05; 1357(1):115-22. PMID: 9202182.
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    78. Lu S, Davies PJ. Regulation of the expression of the tissue transglutaminase gene by DNA methylation. Proc Natl Acad Sci U S A. 1997 Apr 29; 94(9):4692-7. PMID: 9114053.
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    79. Mukherjee R, Davies PJ, Crombie DL, Bischoff ED, Cesario RM, Jow L, Hamann LG, Boehm MF, Mondon CE, Nadzan AM, Paterniti JR, Heyman RA. Sensitization of diabetic and obese mice to insulin by retinoid X receptor agonists. Nature. 1997 Mar 27; 386(6623):407-10. PMID: 9121558.
      View in: PubMed
    80. Zhu YX, Davies PJ. The Control of Apical Bud Growth and Senescence by Auxin and Gibberellin in Genetic Lines of Peas. Plant Physiol. 1997 Feb; 113(2):631-637. PMID: 12223631.
      View in: PubMed
    81. Shalinsky DR, Bischoff ED, Lamph WW, Zhang L, Boehm MF, Davies PJ, Nadzan AM, Heyman RA. A novel retinoic acid receptor-selective retinoid, ALRT1550, has potent antitumor activity against human oral squamous carcinoma xenografts in nude mice. Cancer Res. 1997 Jan 01; 57(1):162-8. PMID: 8988059.
      View in: PubMed
    82. Lippman SM, Davies PJ. Retinoids, neoplasia and differentiation therapy. Cancer Chemother Biol Response Modif. 1997; 17:349-62. PMID: 9551220.
      View in: PubMed
    83. Standeven AM, Davies PJ, Chandraratna RA, Mader DR, Johnson AT, Thomazy VA. Retinoid-induced epiphyseal plate closure in guinea pigs. Fundam Appl Toxicol. 1996 Nov; 34(1):91-8. PMID: 8937896.
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    84. Klein ES, Pino ME, Johnson AT, Davies PJ, Nagpal S, Thacher SM, Krasinski G, Chandraratna RA. Identification and functional separation of retinoic acid receptor neutral antagonists and inverse agonists. J Biol Chem. 1996 Sep 13; 271(37):22692-6. PMID: 8798442.
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    85. Beard RL, Colon DF, Song TK, Davies PJ, Kochhar DM, Chandraratna RA. Synthesis and structure-activity relationships of retinoid X receptor selective diaryl sulfide analogs of retinoic acid. J Med Chem. 1996 Aug 30; 39(18):3556-63. PMID: 8784454.
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    86. Yan ZH, Noonan S, Nagy L, Davies PJ, Stein JP. Retinoic acid induction of the tissue transglutaminase promoter is mediated by a novel response element. Mol Cell Endocrinol. 1996 Jul 01; 120(2):203-12. PMID: 8832580.
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    87. Nagy L, Thomázy VA, Chandraratna RA, Heyman RA, Davies PJ. Retinoid-regulated expression of BCL-2 and tissue transglutaminase during the differentiation and apoptosis of human myeloid leukemia (HL-60) cells. Leuk Res. 1996 Jun; 20(6):499-505. PMID: 8709622.
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    88. Shalinsky DR, Bischoff ED, Gregory ML, Lamph WW, Heyman RA, Hayes JS, Thomazy V, Davies PJ. Enhanced antitumor efficacy of cisplatin in combination with ALRT1057 (9-cis retinoic acid) in human oral squamous carcinoma xenografts in nude mice. Clin Cancer Res. 1996 Mar; 2(3):511-20. PMID: 9816198.
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    89. Yang T, Davies PJ, Reid JB. Genetic Dissection of the Relative Roles of Auxin and Gibberellin in the Regulation of Stem Elongation in Intact Light-Grown Peas. Plant Physiol. 1996 Mar; 110(3):1029-1034. PMID: 12226239.
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    90. Nagy L, Saydak M, Shipley N, Lu S, Basilion JP, Yan ZH, Syka P, Chandraratna RA, Stein JP, Heyman RA, Davies PJ. Identification and characterization of a versatile retinoid response element (retinoic acid receptor response element-retinoid X receptor response element) in the mouse tissue transglutaminase gene promoter. J Biol Chem. 1996 Feb 23; 271(8):4355-65. PMID: 8626785.
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    91. Mian S, el Alaoui S, Lawry J, Gentile V, Davies PJ, Griffin M. The importance of the GTP-binding protein tissue transglutaminase in the regulation of cell cycle progression. FEBS Lett. 1995 Aug 14; 370(1-2):27-31. PMID: 7649299.
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    92. Shalinsky DR, Bischoff ED, Gregory ML, Gottardis MM, Hayes JS, Lamph WW, Heyman RA, Shirley MA, Cooke TA, Davies PJ, et al. Retinoid-induced suppression of squamous cell differentiation in human oral squamous cell carcinoma xenografts (line 1483) in athymic nude mice. Cancer Res. 1995 Jul 15; 55(14):3183-91. PMID: 7541715.
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    93. Nagy L, Thomázy VA, Shipley GL, Fésüs L, Lamph W, Heyman RA, Chandraratna RA, Davies PJ. Activation of retinoid X receptors induces apoptosis in HL-60 cell lines. Mol Cell Biol. 1995 Jul; 15(7):3540-51. PMID: 7791761.
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    94. Lu S, Saydak M, Gentile V, Stein JP, Davies PJ. Isolation and characterization of the human tissue transglutaminase gene promoter. J Biol Chem. 1995 Apr 28; 270(17):9748-56. PMID: 7730352.
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    95. Mehta AM, Saftner RA, Mehta RA, Davies PJ. Identification of Posttranslationally Modified 18-Kilodalton Protein from Rice as Eukaryotic Translation Initiation Factor 5A. Plant Physiol. 1994 Dec; 106(4):1413-1419. PMID: 12232418.
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    96. Melino G, Annicchiarico-Petruzzelli M, Piredda L, Candi E, Gentile V, Davies PJ, Piacentini M. Tissue transglutaminase and apoptosis: sense and antisense transfection studies with human neuroblastoma cells. Mol Cell Biol. 1994 Oct; 14(10):6584-96. PMID: 7935379.
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    97. McCormack SA, Wang JY, Viar MJ, Tague L, Davies PJ, Johnson LR. Polyamines influence transglutaminase activity and cell migration in two cell lines. Am J Physiol. 1994 Sep; 267(3 Pt 1):C706-14. PMID: 7943199.
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    98. Gentile V, Davies PJ, Baldini A. The human tissue transglutaminase gene maps on chromosome 20q12 by in situ fluorescence hybridization. Genomics. 1994 Mar 15; 20(2):295-7. PMID: 7912692.
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    99. Yang T, Law DM, Davies PJ. Magnitude and Kinetics of Stem Elongation Induced by Exogenous Indole-3-Acetic Acid in Intact Light-Grown Pea Seedlings. Plant Physiol. 1993 Jul; 102(3):717-724. PMID: 12231860.
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    100. Davies PJ, Hedrick MS, Jones DR. Neuromuscular control of the glottis in a primitive air-breathing fish, Amia calva. Am J Physiol. 1993 Jan; 264(1 Pt 2):R204-10. PMID: 8430880.
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    101. Gentile V, Thomazy V, Piacentini M, Fesus L, Davies PJ. Expression of tissue transglutaminase in Balb-C 3T3 fibroblasts: effects on cellular morphology and adhesion. J Cell Biol. 1992 Oct; 119(2):463-74. PMID: 1356992.
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    102. Behringer FJ, Davies PJ. Indole-3-acetic acid levels after phytochrome-mediated changes in the stem elongation rate of dark- and light-grown Pisum seedlings. Planta. 1992 Aug; 188(1):85-92. PMID: 24178203.
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    103. Schroeder WT, Thacher SM, Stewart-Galetka S, Annarella M, Chema D, Siciliano MJ, Davies PJ, Tang HY, Sowa BA, Duvic M. Type I keratinocyte transglutaminase: expression in human skin and psoriasis. J Invest Dermatol. 1992 Jul; 99(1):27-34. PMID: 1351505.
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    104. Piacentini M, Cerù MP, Dini L, Di Rao M, Piredda L, Thomazy V, Davies PJ, Fesus L. In vivo and in vitro induction of 'tissue' transglutaminase in rat hepatocytes by retinoic acid. Biochim Biophys Acta. 1992 Jun 10; 1135(2):171-9. PMID: 1352130.
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    105. Zhu YX, Davies PJ, Halinska A. Metabolism of Gibberellin A(12) and A(12)-Aldehyde in Developing Seeds of Pisum sativum L. Plant Physiol. 1991 Sep; 97(1):26-33. PMID: 16668380.
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    106. Fesus L, Nagy L, Basilion JP, Davies PJ. Retinoic acid receptor transcripts in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 1991 Aug 30; 179(1):32-8. PMID: 1715692.
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    107. Gentile V, Saydak M, Chiocca EA, Akande O, Birckbichler PJ, Lee KN, Stein JP, Davies PJ. Isolation and characterization of cDNA clones to mouse macrophage and human endothelial cell tissue transglutaminases. J Biol Chem. 1991 Jan 05; 266(1):478-83. PMID: 1670766.
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    108. Rastogi R, Davies PJ. Polyamine Metabolism in Ripening Tomato Fruit : II. Polyamine Metabolism and Synthesis in Relation to Enhanced Putrescine Content and Storage Life of a/c Tomato Fruit. Plant Physiol. 1991 Jan; 95(1):41-5. PMID: 16667978.
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    109. Rastogi R, Davies PJ. Polyamine metabolism in ripening tomato fruit : I. Identification of metabolites of putrescine and spermidine. Plant Physiol. 1990 Nov; 94(3):1449-55. PMID: 16667852.
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    110. Behringer FJ, Davies PJ, Reid JB. Genetic analysis of the role of gibberellin in the red light inhibition of stem elongation in etiolated seedlings. Plant Physiol. 1990 Oct; 94(2):432-9. PMID: 16667731.
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    111. Law DM, Davies PJ. Comparative indole-3-acetic Acid levels in the slender pea and other pea phenotypes. Plant Physiol. 1990 Aug; 93(4):1539-43. PMID: 16667653.
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    112. Behringer FJ, Cosgrove DJ, Reid JB, Davies PJ. Physical basis for altered stem elongation rates in internode length mutants of Pisum. Plant Physiol. 1990; 94:166-73. PMID: 11537473.
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    113. Halinska A, Davies PJ, Lee JW, Zhu YX. Further identification of endogenous gibberellins in the shoots of pea, line g2. Plant Physiol. 1989 Dec; 91(4):1255-8. PMID: 16667171.
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    114. Chiocca EA, Davies PJ, Stein JP. Regulation of tissue transglutaminase gene expression as a molecular model for retinoid effects on proliferation and differentiation. J Cell Biochem. 1989 Mar; 39(3):293-304. PMID: 2565341.
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    115. Hamilton DA, Davies PJ. Sucrose and Malic Acid as the Compounds Exported to the Apical Bud of Pea following CO(2) Labeling of the Fruit : No Evidence for a Senescence Factor. Plant Physiol. 1988 Oct; 88(2):466-72. PMID: 16666328.
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    116. Davies PJ, Basilion JP, Chiocca EA, Johnson J, Poddar S, Stein JP. Retinoids as generalized regulators of cellular growth and differentiation. Am J Med Sci. 1988 Sep; 296(3):164-70. PMID: 2902793.
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    117. Chiocca EA, Davies PJ, Stein JP. The molecular basis of retinoic acid action. Transcriptional regulation of tissue transglutaminase gene expression in macrophages. J Biol Chem. 1988 Aug 15; 263(23):11584-9. PMID: 2900242.
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    118. Hamilton DA, Davies PJ. Mechanism of export of organic material from the developing fruits of pea. Plant Physiol. 1988 Mar; 86(3):956-9. PMID: 16666016.
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    119. Hamilton DA, Davies PJ. Export of organic materials from developing fruits of pea and its possible relation to apical senescence. Plant Physiol. 1988 Mar; 86(3):951-5. PMID: 16666015.
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    120. Kelly MO, Davies PJ. Photoperiodic and genetic control of carbon partitioning in peas and its relationship to apical senescence. Plant Physiol. 1988 Mar; 86(3):978-82. PMID: 16666020.
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    121. Dibble AR, Davies PJ, Mutschler MA. Polyamine content of long-keeping alcobaca tomato fruit. Plant Physiol. 1988 Feb; 86(2):338-40. PMID: 16665907.
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    122. Davies PJ, Chiocca EA, Basilion JP, Poddar S, Stein JP. Transglutaminases and their regulation: implications for polyamine metabolism. Adv Exp Med Biol. 1988; 250:391-401. PMID: 2908219.
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    123. Davies PJ, Chiocca EA, Stein JP. Retinoid--regulated expression of tissue transglutaminase in normal and leukemic myeloid cells. Adv Exp Med Biol. 1988; 231:63-71. PMID: 2901195.
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    124. Bushey DF, Law DM, Davies PJ. High-performance liquid chromatography analysis of 1-aminocyclopropane-1-carboxylic acid using o-phthaldialdehyde precolumn derivatization. Anal Biochem. 1987 Nov 15; 167(1):31-6. PMID: 3434798.
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    125. Johnson JD, Davies PJ. Pertussis toxin inhibits retinoic acid-induced expression of tissue transglutaminase in macrophages. J Biol Chem. 1986 Nov 15; 261(32):14982-6. PMID: 2876993.
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    126. Maki SL, Brenner ML, Birnberg PR, Davies PJ, Krick TP. Identification of Pea Gibberellins by Studying [C]GA(12)-Aldehyde Metabolism. Plant Physiol. 1986 Aug; 81(4):984-90. PMID: 16664970.
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    127. Davies PJ, Birnberg PR, Maki SL, Brenner ML. Photoperiod modification of [C]gibberellin a(12) aldehyde metabolism in shoots of pea, line g2. Plant Physiol. 1986 Aug; 81(4):991-6. PMID: 16664971.
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    128. Murtaugh MP, Dennison O, Stein JP, Davies PJ. Retinoic acid-induced gene expression in normal and leukemic myeloid cells. J Exp Med. 1986 May 01; 163(5):1325-30. PMID: 2871126.
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    129. Murtaugh MP, Moore WT, Davies PJ. Cyclic AMP potentiates the retinoic acid-induced expression of tissue transglutaminase in peritoneal macrophages. J Biol Chem. 1986 Jan 15; 261(2):614-21. PMID: 2867089.
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    130. Smith MA, Davies PJ. Effect of photoperiod on polyamine metabolism in apical buds of g2 peas in relation to the induction of apical senescence. Plant Physiol. 1985 Oct; 79(2):400-5. PMID: 16664421.
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    131. Smith MA, Davies PJ. Separation and quantitation of polyamines in plant tissue by high performance liquid chromatography of their dansyl derivatives. Plant Physiol. 1985 May; 78(1):89-91. PMID: 16664216.
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    132. Smith MA, Davies PJ, Reid JB. Role of polyamines in gibberellin-induced internode growth in peas. Plant Physiol. 1985 May; 78(1):92-9. PMID: 16664217.
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    133. Davies PJ, Murtaugh MP, Moore WT, Johnson GS, Lucas D. Retinoic acid-induced expression of tissue transglutaminase in human promyelocytic leukemia (HL-60) cells. J Biol Chem. 1985 Apr 25; 260(8):5166-74. PMID: 2859286.
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    134. Mehta K, Lopez-Berestein G, Moore WT, Davies PJ. Interferon-gamma requires serum retinoids to promote the expression of tissue transglutaminase in cultured human blood monocytes. J Immunol. 1985 Apr; 134(4):2053-6. PMID: 2857744.
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    135. Moore WT, Murtaugh MP, Davies PJ. Retinoic acid-induced expression of tissue transglutaminase in mouse peritoneal macrophages. J Biol Chem. 1984 Oct 25; 259(20):12794-802. PMID: 6149218.
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    136. Mehta K, Murtaugh MP, Juliano RL, Davies PJ. Phagocytosis inhibits the expression of tissue transglutaminase in mouse peritoneal macrophages. J Immunol. 1984 May; 132(5):2552-8. PMID: 6143781.
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    137. Murtaugh MP, Arend WP, Davies PJ. Induction of tissue transglutaminase in human peripheral blood monocytes. J Exp Med. 1984 Jan 01; 159(1):114-25. PMID: 6141210.
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    138. Murtaugh MP, Mehta K, Johnson J, Myers M, Juliano RL, Davies PJ. Induction of tissue transglutaminase in mouse peritoneal macrophages. J Biol Chem. 1983 Sep 25; 258(18):11074-81. PMID: 6136512.
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    139. Davies PJ, Emshwiller E, Gianfagna TJ, Proebsting WM, Noma M, Pharis RP. The endogenous gibberellins of vegetative and reproductive tissue of G2 peas. Planta. 1982 May; 154(3):266-72. PMID: 24276070.
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    140. Gianfagna TJ, Davies PJ. The relationship between fruit growth and apical senescence in the G2 line of peas. Planta. 1981 Jul; 152(4):356-64. PMID: 24301032.
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    141. Davies PJ, Rubery PH. Components of auxin transport in stem segments of Pisum sativum L. Planta. 1978 Jan; 142(2):211-9. PMID: 24408105.
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    142. Proebsting WM, Davies PJ, Marx GA. Photoperiod-induced changes in gibberellin metabolism in relation to apical growth and senescence in genetic lines of peas (Pisum sativum L.). Planta. 1978 Jan; 141(3):231-8. PMID: 24414866.
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    143. Kinnersley AM, Davies PJ. Effect of Temperature on Phytochrome-mediated Responses in Seedlings of Mustard. Plant Physiol. 1977 Jul; 60(1):175-7. PMID: 16660033.
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    144. Parrish DJ, Davies PJ. Emergent growth: an auxin-mediated response. Plant Physiol. 1977 Apr; 59(4):745-9. PMID: 16659930.
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    145. Parrish DJ, Davies PJ. On the Relationship between Extracellular pH and the Growth of Excised Pea Stem Segments. Plant Physiol. 1977 Apr; 59(4):574-8. PMID: 16659896.
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    146. Proebsting WM, Davies PJ, Marx GA. Evidence for a graft-transmissible substance which delays apical senescence in Pisum sativum L. Planta. 1977 Jan; 135(1):93-4. PMID: 24419899.
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    147. Parrish DJ, Davies PJ. Light-dependent Elongation of Anaerobically Maintained Green Pea Stem Segments and Its Implications. Plant Physiol. 1976 Dec; 58(6):757-60. PMID: 16659761.
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    148. Kinnersley AM, Davies PJ. Comparison of Three Phytochrome-mediated Processes in the Hypocotyl of Mustard. Plant Physiol. 1976 Dec; 58(6):777-82. PMID: 16659765.
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    149. Proebsting WM, Davies PJ, Marx GA. Photoperiodic control of apical senescence in a genetic line of peas. Plant Physiol. 1976 Dec; 58(6):800-2. PMID: 16659771.
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    150. Davies PJ. Bound auxin formation in growing stems. Plant Physiol. 1976 Feb; 57(2):197-202. PMID: 16659450.
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    151. Malik NS, Davies PJ. The effect of fruit development on the growth capacity of apical meristems. Planta. 1976 Jan; 129(2):191-2. PMID: 24430912.
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    152. Parrish DJ, Davies PJ. The influence of aging conditions on the short term growth of green pea stem segments. Plant Physiol. 1975 Mar; 55(3):586-8. PMID: 16659129.
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    153. Davies PJ, Mitchell EK. Transport of indoleacetic acid in intact roots of Phaseolus coccineus. Planta. 1972 Jun; 105(2):139-54. PMID: 24477753.
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    154. Davies PJ, Galston AW. Labeled indole-macromolecular conjugates from growing stems supplied with labeled indoleacetic Acid : I. Fractionation. Plant Physiol. 1971 Mar; 47(3):435-41. PMID: 16657637.
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    155. Galston AW, Davies PJ. Hormonal regulation in higher plants. Science. 1969 Mar 21; 163(3873):1288-97. PMID: 4886673.
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