GEORGE VAN BUREN

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
Address7200 CAMBRIDGE
Houston, TX 77030
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    George Van Buren, II, M.D. is an assistant professor of surgery in the Division of Surgical Oncology of the Michael E. DeBakey Department of Surgery at Baylor College of Medicine. Dr. Van Buren is a board-certified surgeon specializing surgical oncology and pancreatic disorders.
    Dr. Van Buren earned his undergraduate degree at the University of Texas at Austin and his medical degree at the University of Texas Medical School at Houston. He completed his general surgery residency at the University of Texas Medical School at Houston. During that time period, he spent two years at MD Anderson Cancer Center as an NIH T32 research fellow studying pancreatic cancer, colorectal cancer, and neuroendocrine tumors. He completed his surgical oncology fellowship at the University of Pittsburgh Medical Center in the Translational Pancreas Research Track.
    During Dr. Van Buren’s research and clinical fellowships, he was able to expand upon his interest in gastrointestinal surgical oncology. Specifically, his training had a heavy emphasis on upper gastrointestinal and hepatobiliary malignancies with exposure to wide breadth of cases, including specialized procedures such as robotic pancreatic surgery and minimally invasive lower gastrointestinal surgery.
    Dr. Van Buren is active in both patient care and research. He has been involved in both basic science and clinical research and believes heavily in the surgeon’s role as a leader of the translational research team. His goals are to provide high quality clinical care while offering his patients access to innovative clinical and therapeutic trials

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Mickel TA, Kutlu OC, Silberfein EJ, Hsu C, Chai CY, Fisher WE, Van Buren G, Camp ER. Factors associated with inability to return to intended oncologic treatment in pancreatic cancer. Am J Surg. 2022 07; 224(1 Pt B):635-640. PMID: 35249728.
      Citations:    Fields:    Translation:Humans
    2. Zhang J, Sans M, DeHoog RJ, Garza KY, King ME, Feider CL, Bensussan A, Keating MF, Lin JQ, Povilaitis SC, Katta N, Milner TE, Yu W, Nagi C, Dhingra S, Pirko C, Brahmbhatt KA, Van Buren G, Carter S, Thompson A, Grogan RH, Suliburk J, Eberlin LS. Clinical Translation and Evaluation of a Handheld and Biocompatible Mass Spectrometry Probe for Surgical Use. Clin Chem. 2021 09 01; 67(9):1271-1280. PMID: 34263289.
      Citations:    Fields:    Translation:Humans
    3. Brubaker LS, Casciani F, Fisher WE, Wood AL, Cagigas MN, Trudeau MT, Parikh VJ, Baugh KA, Asbun HJ, Ball CG, Behrman SW, Berger AC, Bloomston MP, Callery MP, Christein JD, Fernandez-Del Castillo C, Dillhoff ME, Dixon E, House MG, Hughes SJ, Kent TS, Kunstman JW, Wolfgang CL, Zureikat AH, Vollmer CM, Van Buren G. A risk-adjusted analysis of drain use in pancreaticoduodenectomy: Some is good, but more may not be better. Surgery. 2022 04; 171(4):1058-1066. PMID: 34433515.
      Citations:    Fields:    Translation:Humans
    4. King ME, Zhang J, Lin JQ, Garza KY, DeHoog RJ, Feider CL, Bensussan A, Sans M, Krieger A, Badal S, Keating MF, Woody S, Dhingra S, Yu W, Pirko C, Brahmbhatt KA, Van Buren G, Fisher WE, Suliburk J, Eberlin LS. Rapid diagnosis and tumor margin assessment during pancreatic cancer surgery with the MasSpec Pen technology. Proc Natl Acad Sci U S A. 2021 07 13; 118(28). PMID: 34260388.
      Citations: 4     Fields:    Translation:Humans
    5. Le DT, Huynh TR, Burt B, Van Buren G, Abeynaike SA, Zalfa C, Nikzad R, Kheradmand F, Tyner JJ, Paust S. Natural killer cells and cytotoxic T lymphocytes are required to clear solid tumor in a patient-derived xenograft. JCI Insight. 2021 07 08; 6(13). PMID: 34081628.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    6. Wiseman JT, Chakedis J, Beal EW, Paredes A, McElhany A, Fang A, Manilchuk A, Ellison C, Van Buren G, Pawlik TM, Schmidt CR, Fisher WE, Dillhoff M. Hemoglobin A1c Is a Predictor of New Insulin Dependence After Partial Pancreatectomy: A Multi-Institutional Analysis. J Gastrointest Surg. 2021 12; 25(12):3119-3129. PMID: 33948858.
      Citations:    Fields:    Translation:Humans
    7. Ripley RT, Palivela N, Groth SS, Choi EA, Cornwell LD, Carrott PW, Van Buren G, Splawn TG, Sugarbaker DJ, Burt BM. Diagnostic Laparoscopy Improves Staging of Malignant Pleural Mesothelioma With Routine Positron Emission Tomography Imaging. Ann Thorac Surg. 2021 11; 112(5):1568-1574. PMID: 33275932.
      Citations: 1     Fields:    Translation:Humans
    8. Van Buren G, Vollmer CM. The Landmark Series: Mitigation of the Postoperative Pancreatic Fistula. Ann Surg Oncol. 2021 Feb; 28(2):1052-1059. PMID: 33089395.
      Citations: 1     Fields:    Translation:Humans
    9. Shah KP, Baugh KA, Brubaker LS, Van Buren G, Villafane-Ferriol N, McElhany AL, Mohamed S, Silberfein EJ, Hsu C, Massarweh NN, Tran Cao HS, Mendez-Reyes JE, Fisher WE. Long-Term Assessment of Pancreatic Function After Pancreatectomy for Cystic Neoplasms. J Surg Res. 2020 03; 247:547-555. PMID: 31740011.
      Citations:    Fields:    Translation:Humans
    10. Majumder S, Taylor WR, Yab TC, Berger CK, Dukek BA, Cao X, Foote PH, Wu CW, Mahoney DW, Aslanian HR, Fernández-Del Castillo C, Doyle LA, Farrell JJ, Fisher WE, Lee LS, Lee YN, Park W, Rodrigues C, Gould Rothberg BE, Salem RR, Simeone DM, Urs S, Van Buren G, Smyrk TC, Allawi HT, Lidgard GP, Raimondo M, Chari ST, Kendrick ML, Kisiel JB, Topazian MD, Ahlquist DA. Novel Methylated DNA Markers Discriminate Advanced Neoplasia in Pancreatic Cysts: Marker Discovery, Tissue Validation, and Cyst Fluid Testing. Am J Gastroenterol. 2019 09; 114(9):1539-1549. PMID: 31306149.
      Citations: 9     Fields:    Translation:HumansCells
    11. Polireddy K, Singh K, Pruski M, Jones NC, Manisundaram NV, Ponnela P, Ouellette M, Van Buren G, Younes M, Bynon JS, Dar WA, Bailey JM. Mutant p53R175H promotes cancer initiation in the pancreas by stabilizing HSP70. Cancer Lett. 2019 07 01; 453:122-130. PMID: 30946870.
      Citations: 5     Fields:    Translation:HumansCells
    12. Poteet E, Liu D, Liang Z, Van Buren G, Chen C, Yao Q. Mesothelin and TGF-a predict pancreatic cancer cell sensitivity to EGFR inhibitors and effective combination treatment with trametinib. PLoS One. 2019; 14(3):e0213294. PMID: 30921351.
      Citations: 4     Fields:    Translation:HumansCells
    13. Villafane-Ferriol N, Baugh KA, McElhany AL, Van Buren G, Fang A, Tashakori EK, Reyes JEM, Cao HST, Silberfein EJ, Massarweh N, Hsu C, Barakat O, Schmidt C, Zyromski NJ, Dillhoff M, Villarreal JA, Fisher WE. Evidence Versus Practice in Early Drain Removal After Pancreatectomy. J Surg Res. 2019 04; 236:332-339. PMID: 30694774.
      Citations: 2     Fields:    Translation:Humans
    14. Baugh KA, Villafane N, Farinas C, Dhingra S, Silberfein EJ, Massarweh NN, Cao HT, Fisher WE, Van Buren G. Pancreatic Incidentalomas: A Management Algorithm for Identifying Ectopic Spleens. J Surg Res. 2019 04; 236:144-152. PMID: 30694749.
      Citations: 3     Fields:    Translation:Humans
    15. Song X, Chen H, Zhang C, Yu Y, Chen Z, Liang H, Van Buren G, McElhany AL, Fisher WE, Lonard DM, O'Malley BW, Wang J. SRC-3 inhibition blocks tumor growth of pancreatic ductal adenocarcinoma. Cancer Lett. 2019 02 01; 442:310-319. PMID: 30423406.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    16. Fisher WE, Cruz-Monserrate Z, McElhany AL, Lesinski GB, Hart PA, Ghosh R, Van Buren G, Fishman DS, Rinaudo JAS, Serrano J, Srivastava S, Mace T, Topazian M, Feng Z, Yadav D, Pandol SJ, Hughes SJ, Liu RY, Lu E, Orr R, Whitcomb DC, Abouhamze AS, Steen H, Sellers ZM, Troendle DM, Uc A, Lowe ME, Conwell DL. Standard Operating Procedures for Biospecimen Collection, Processing, and Storage: From the Consortium for the Study of Chronic Pancreatitis, Diabetes, and Pancreatic Cancer. Pancreas. 2018 Nov/Dec; 47(10):1213-1221. PMID: 30325860.
      Citations: 6     Fields:    Translation:Humans
    17. Baugh KA, Tran Cao HS, van Buren G, Silberfein EJ, Hsu C, Chai C, Barakat O, Fisher WE, Massarweh NN. Understaging of clinical stage I pancreatic cancer and the impact of multimodality therapy. Surgery. 2019 02; 165(2):307-314. PMID: 30243481.
      Citations: 4     Fields:    Translation:Humans
    18. Mohammed S, Mendez-Reyes JE, McElhany A, Gonzales-Luna D, Van Buren G, Bland DS, Villafane-Ferriol N, Pierzynski JA, West CA, Silberfein EJ, Fisher WE. Venous thrombosis following pancreaticoduodenectomy with venous resection. J Surg Res. 2018 08; 228:271-280. PMID: 29907222.
      Citations: 2     Fields:    Translation:Humans
    19. Villafane-Ferriol N, Van Buren G, Mendez-Reyes JE, McElhany AL, Massarweh NN, Silberfein EJ, Hsu C, Tran Cao HS, Schmidt C, Zyromski NJ, Dillhoff ME, Roch A, Oliva E, Smith AC, Zhang Q, Fisher WE. Sequential drain amylase to guide drain removal following pancreatectomy. HPB (Oxford). 2018 06; 20(6):514-520. PMID: 29478737.
      Citations: 3     Fields:    Translation:Humans
    20. Villafane-Ferriol N, Shah RM, Mohammed S, Van Buren G, Barakat O, Massarweh NN, Tran Cao HS, Silberfein EJ, Hsu C, Fisher WE. Evidence-Based Management of Drains Following Pancreatic Resection: A Systematic Review. Pancreas. 2018 01; 47(1):12-17. PMID: 29232341.
      Citations: 9     Fields:    Translation:Humans
    21. Van Buren G, Bloomston M, Schmidt CR, Behrman SW, Zyromski NJ, Ball CG, Morgan KA, Hughes SJ, Karanicolas PJ, Allendorf JD, Vollmer CM, Ly Q, Brown KM, Velanovich V, Winter JM, McElhany AL, Muscarella P, Schmidt CM, House MG, Dixon E, Dillhoff ME, Trevino JG, Hallet J, Coburn NSG, Nakeeb A, Behrns KE, Sasson AR, Ceppa EP, Abdel-Misih SRZ, Riall TS, Silberfein EJ, Ellison EC, Adams DB, Hsu C, Tran Cao HS, Mohammed S, Villafañe-Ferriol N, Barakat O, Massarweh NN, Chai C, Mendez-Reyes JE, Fang A, Jo E, Mo Q, Fisher WE. A Prospective Randomized Multicenter Trial of Distal Pancreatectomy With and Without Routine Intraperitoneal Drainage. Ann Surg. 2017 09; 266(3):421-431. PMID: 28692468.
      Citations: 28     Fields:    Translation:Humans
    22. Tran Cao HS, Zhang Q, Sada YH, Silberfein EJ, Hsu C, Van Buren G, Chai C, Katz MHG, Fisher WE, Massarweh NN. Value of lymph node positivity in treatment planning for early stage pancreatic cancer. Surgery. 2017 09; 162(3):557-567. PMID: 28666686.
      Citations: 8     Fields:    Translation:Humans
    23. Gilliland TM, Villafane-Ferriol N, Shah KP, Shah RM, Tran Cao HS, Massarweh NN, Silberfein EJ, Choi EA, Hsu C, McElhany AL, Barakat O, Fisher W, Van Buren G. Nutritional and Metabolic Derangements in Pancreatic Cancer and Pancreatic Resection. Nutrients. 2017 Mar 07; 9(3). PMID: 28272344.
      Citations: 46     Fields:    Translation:Humans
    24. Yong LK, Lai S, Liang Z, Poteet E, Chen F, van Buren G, Fisher W, Mo Q, Chen C, Yao Q. Overexpression of Semaphorin-3E enhances pancreatic cancer cell growth and associates with poor patient survival. Oncotarget. 2016 Dec 27; 7(52):87431-87448. PMID: 27911862.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    25. Van Buren G. Reply. Pancreas. 2016 08; 45(7):e34-5. PMID: 27400158.
      Citations:    Fields:    
    26. Van Buren G, Fisher WE. Pancreaticoduodenectomy Without Drains: Interpretation of the Evidence. Ann Surg. 2016 May; 263(5):e74-6. PMID: 25647060.
      Citations: 2     Fields:    Translation:Humans
    27. Van Buren G, Fisher WE. Pancreaticoduodenectomy Without Drains: Interpretation of the Evidence. Ann Surg. 2016 Feb; 263(2):e20-1. PMID: 25894415.
      Citations: 1     Fields:    Translation:Humans
    28. Gingras MC, Covington KR, Chang DK, Donehower LA, Gill AJ, Ittmann MM, Creighton CJ, Johns AL, Shinbrot E, Dewal N, Fisher WE, Pilarsky C, Grützmann R, Overman MJ, Jamieson NB, Van Buren G, Drummond J, Walker K, Hampton OA, Xi L, Muzny DM, Doddapaneni H, Lee SL, Bellair M, Hu J, Han Y, Dinh HH, Dahdouli M, Samra JS, Bailey P, Waddell N, Pearson JV, Harliwong I, Wang H, Aust D, Oien KA, Hruban RH, Hodges SE, McElhany A, Saengboonmee C, Duthie FR, Grimmond SM, Biankin AV, Wheeler DA, Gibbs RA. Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation. Cell Rep. 2016 Feb 02; 14(4):907-919. PMID: 26804919.
      Citations: 47     Fields:    Translation:HumansCells
    29. Khawja SN, Mohammed S, Silberfein EJ, Musher BL, Fisher WE, Van Buren G. Pancreatic cancer disparities in African Americans. Pancreas. 2015 May; 44(4):522-7. PMID: 25872128.
      Citations: 33     Fields:    Translation:Humans
    30. McMillan MT, Fisher WE, Van Buren G, McElhany A, Bloomston M, Hughes SJ, Winter J, Behrman SW, Zyromski NJ, Velanovich V, Brown K, Morgan KA, Vollmer C. The value of drains as a fistula mitigation strategy for pancreatoduodenectomy: something for everyone? Results of a randomized prospective multi-institutional study. J Gastrointest Surg. 2015 Jan; 19(1):21-30; discussion 30-1. PMID: 25183409.
      Citations: 27     Fields:    Translation:Humans
    31. Mohammed S, Van Buren G, Fisher WE. Pancreatic cancer: advances in treatment. World J Gastroenterol. 2014 Jul 28; 20(28):9354-60. PMID: 25071330.
      Citations: 77     Fields:    Translation:Humans
    32. Van Buren G, Bloomston M, Hughes SJ, Winter J, Behrman SW, Zyromski NJ, Vollmer C, Velanovich V, Riall T, Muscarella P, Trevino J, Nakeeb A, Schmidt CM, Behrns K, Ellison EC, Barakat O, Perry KA, Drebin J, House M, Abdel-Misih S, Silberfein EJ, Goldin S, Brown K, Mohammed S, Hodges SE, McElhany A, Issazadeh M, Jo E, Mo Q, Fisher WE. A randomized prospective multicenter trial of pancreaticoduodenectomy with and without routine intraperitoneal drainage. Ann Surg. 2014 Apr; 259(4):605-12. PMID: 24374513.
      Citations: 84     Fields:    Translation:Humans
    33. Ross A, Mohammed S, Vanburen G, Silberfein EJ, Artinyan A, Hodges SE, Fisher WE. An assessment of the necessity of transfusion during pancreatoduodenectomy. Surgery. 2013 Sep; 154(3):504-11. PMID: 23972656.
      Citations: 23     Fields:    Translation:Humans
    34. Mohammed S, Evans C, VanBuren G, Hodges SE, Silberfein E, Artinyan A, Mo Q, Issazadeh M, McElhany AL, Fisher WE. Treatment of bacteriobilia decreases wound infection rates after pancreaticoduodenectomy. HPB (Oxford). 2014 Jun; 16(6):592-8. PMID: 23992045.
      Citations: 11     Fields:    Translation:Humans
    35. Van Buren G, Ramanathan RK, Krasinskas AM, Smith RP, Abood GJ, Bahary N, Lembersky BC, Shuai Y, Potter DM, Bartlett DL, Zureikat AH, Zeh HJ, Moser AJ. Phase II study of induction fixed-dose rate gemcitabine and bevacizumab followed by 30 Gy radiotherapy as preoperative treatment for potentially resectable pancreatic adenocarcinoma. Ann Surg Oncol. 2013 Nov; 20(12):3787-93. PMID: 23904005.
      Citations: 18     Fields:    Translation:HumansCTClinical Trials
    36. Harvin JA, Van Buren G, Tsao K, Cen P, Ko TC, Wray CJ. Hepatocellular carcinoma survival in uninsured and underinsured patients. J Surg Res. 2011 Apr; 166(2):189-93. PMID: 20638680.
      Citations: 3     Fields:    Translation:Humans
    37. Van Buren G, Gray MJ, Dallas NA, Xia L, Lim SJ, Fan F, Mazar AP, Ellis LM. Targeting the urokinase plasminogen activator receptor with a monoclonal antibody impairs the growth of human colorectal cancer in the liver. Cancer. 2009 Jul 15; 115(14):3360-8. PMID: 19484792.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    38. Dallas NA, Xia L, Fan F, Gray MJ, Gaur P, van Buren G, Samuel S, Kim MP, Lim SJ, Ellis LM. Chemoresistant colorectal cancer cells, the cancer stem cell phenotype, and increased sensitivity to insulin-like growth factor-I receptor inhibition. Cancer Res. 2009 Mar 01; 69(5):1951-7. PMID: 19244128.
      Citations: 252     Fields:    Translation:HumansAnimalsCells
    39. Dallas NA, Gray MJ, Xia L, Fan F, van Buren G, Gaur P, Samuel S, Lim SJ, Arumugam T, Ramachandran V, Wang H, Ellis LM. Neuropilin-2-mediated tumor growth and angiogenesis in pancreatic adenocarcinoma. Clin Cancer Res. 2008 Dec 15; 14(24):8052-60. PMID: 19088020.
      Citations: 40     Fields:    Translation:HumansCells
    40. Fan F, Gray MJ, Dallas NA, Yang AD, Van Buren G, Camp ER, Ellis LM. Effect of chemotherapeutic stress on induction of vascular endothelial growth factor family members and receptors in human colorectal cancer cells. Mol Cancer Ther. 2008 Sep; 7(9):3064-70. PMID: 18790786.
      Citations: 11     Fields:    Translation:HumansCells
    41. Van Buren G, Yang AD, Dallas NA, Gray MJ, Lim SJ, Xia L, Fan F, Somcio R, Wu Y, Hicklin DJ, Ellis LM. Effect of molecular therapeutics on liver regeneration in a murine model. J Clin Oncol. 2008 Apr 10; 26(11):1836-42. PMID: 18398149.
      Citations: 21     Fields:    Translation:Animals
    42. Gray MJ, Van Buren G, Dallas NA, Xia L, Wang X, Yang AD, Somcio RJ, Lin YG, Lim S, Fan F, Mangala LS, Arumugam T, Logsdon CD, Lopez-Berestein G, Sood AK, Ellis LM. Therapeutic targeting of neuropilin-2 on colorectal carcinoma cells implanted in the murine liver. J Natl Cancer Inst. 2008 Jan 16; 100(2):109-20. PMID: 18182619.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    43. Dallas NA, Fan F, Gray MJ, Van Buren G, Lim SJ, Xia L, Ellis LM. Functional significance of vascular endothelial growth factor receptors on gastrointestinal cancer cells. Cancer Metastasis Rev. 2007 Dec; 26(3-4):433-41. PMID: 17786539.
      Citations: 24     Fields:    Translation:HumansAnimals
    44. Van Buren G, Teichgraeber DC, Ghorbani RP, Souchon EA. Sequential stenotic strictures of the small bowel leading to obstruction. World J Gastroenterol. 2007 Oct 28; 13(40):5391-3. PMID: 17879413.
      Citations: 4     Fields:    Translation:Humans
    45. Van Buren G, Rashid A, Yang AD, Abdalla EK, Gray MJ, Liu W, Somcio R, Fan F, Camp ER, Yao JC, Ellis LM. The development and characterization of a human midgut carcinoid cell line. Clin Cancer Res. 2007 Aug 15; 13(16):4704-12. PMID: 17699847.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    46. Van Buren G, Camp ER, Yang AD, Gray MJ, Fan F, Somcio R, Ellis LM. The role of nitric oxide in mediating tumour blood flow. Expert Opin Ther Targets. 2006 Oct; 10(5):689-701. PMID: 16981826.
      Citations: 5     Fields:    Translation:HumansAnimals
    47. Yang AD, Fan F, Camp ER, van Buren G, Liu W, Somcio R, Gray MJ, Cheng H, Hoff PM, Ellis LM. Chronic oxaliplatin resistance induces epithelial-to-mesenchymal transition in colorectal cancer cell lines. Clin Cancer Res. 2006 Jul 15; 12(14 Pt 1):4147-53. PMID: 16857785.
      Citations: 233     Fields:    Translation:HumansCells
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