Header Logo

KENNETH GABBAY

TitleProfessor Emeritus
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address
vCardDownload vCard
    Other Positions
    TitleProfessor Emeritus
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


    Collapse ORNG Applications 
    Collapse Verify Publications

    Collapse Research 
    Collapse research activities and funding
    R01HL034999     (GABBAY, KENNETH H)Feb 1, 1985 - Jul 31, 1987
    NIH
    BLOOD GLUCOSE, HGB A1C, AND DIABETIC VASCULAR DISEASE
    Role: Principal Investigator
    R01DK038773     (GABBAY, KENNETH H)Sep 1, 1986 - Aug 31, 1997
    NIH
    GROWTH FACTORS AND THEIR INHIBITORS IN RENAL FAILURE
    Role: Principal Investigator
    R01DK039044     (GABBAY, KENNETH H)Aug 1, 1987 - Jul 31, 1993
    NIH
    BLOOD GLUCOSE-HEMOGLOBIN A1C &DIABETIC VASCULAR DISEASE
    Role: Principal Investigator
    R01DK041113     (GABBAY, KENNETH H)Jan 1, 1989 - Dec 31, 1992
    NIH
    AIDS IN INFANTS &CHILDREN--ENDOCRINE &WASTING ASPECTS
    Role: Principal Investigator
    R01EY011018     (GABBAY, KENNETH H)Jun 1, 1995 - Jul 31, 2004
    NIH
    ALDO/KETO REDUCTASES AND DIABETIC COMPLICATIONS
    Role: Principal Investigator
    R01DK055137     (GABBAY, KENNETH H)Sep 30, 1998 - Aug 31, 2003
    NIH
    SPECIES SUSCEPTIBILITY TO DIABETIC COMPLICATIONS
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Thiagarajan D, O' Shea K, Sreejit G, Ananthakrishnan R, Quadri N, Li Q, Schmidt AM, Gabbay K, Ramasamy R. Aldose reductase modulates acute activation of mesenchymal markers via the ß-catenin pathway during cardiac ischemia-reperfusion. PLoS One. 2017; 12(11):e0188981. PMID: 29190815.
      Citations:    Fields:    Translation:AnimalsCells
    2. Gabbay KH. Insulin sensitivity is a Rubik's Cube. Am J Clin Nutr. 2016 06; 103(6):1381-2. PMID: 27194307.
      Citations:    Fields:    Translation:Humans
    3. Abdillahi M, Ananthakrishnan R, Vedantham S, Shang L, Zhu Z, Rosario R, Zirpoli H, Bohren KM, Gabbay KH, Ramasamy R. Aldose reductase modulates cardiac glycogen synthase kinase-3ß phosphorylation during ischemia-reperfusion. Am J Physiol Heart Circ Physiol. 2012 Aug 01; 303(3):H297-308. PMID: 22661511.
      Citations: 11     Translation:HumansAnimalsCells
    4. Gabbay KH, Bohren KM, Morello R, Bertin T, Liu J, Vogel P. Ascorbate synthesis pathway: dual role of ascorbate in bone homeostasis. J Biol Chem. 2010 Jun 18; 285(25):19510-20. PMID: 20410296.
      Citations: 32     Fields:    Translation:AnimalsCells
    5. Bohren KM, Gabbay KH, Owerbach D. Affinity chromatography of native SUMO proteins using His-tagged recombinant UBC9 bound to Co2+-charged talon resin. Protein Expr Purif. 2007 Aug; 54(2):289-94. PMID: 17459725.
      Citations: 13     Fields:    Translation:HumansCells
    6. Owerbach D, McKay EM, Yeh ET, Gabbay KH, Bohren KM. A proline-90 residue unique to SUMO-4 prevents maturation and sumoylation. Biochem Biophys Res Commun. 2005 Nov 18; 337(2):517-20. PMID: 16198310.
      Citations: 77     Fields:    Translation:HumansCells
    7. Bohren KM, Brownlee JM, Milne AC, Gabbay KH, Harrison DH. The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism. Biochim Biophys Acta. 2005 May 15; 1748(2):201-12. PMID: 15769597.
      Citations: 2     Fields:    Translation:HumansCells
    8. Gabbay KH. Aldose reductase inhibition in the treatment of diabetic neuropathy: where are we in 2004? Curr Diab Rep. 2004 Dec; 4(6):405-8. PMID: 15539002.
      Citations: 10     Fields:    Translation:Humans
    9. Owerbach D, Piña L, Gabbay KH. Association of a CAG/CAA repeat sequence in the TBP gene with type I diabetes. Biochem Biophys Res Commun. 2004 Oct 22; 323(3):865-9. PMID: 15381080.
      Citations: 1     Fields:    Translation:HumansCells
    10. Owerbach D, Piña L, Gabbay KH. A 212-kb region on chromosome 6q25 containing the TAB2 gene is associated with susceptibility to type 1 diabetes. Diabetes. 2004 Jul; 53(7):1890-3. PMID: 15220215.
      Citations: 10     Fields:    Translation:HumansCells
    11. Bohren KM, Nadkarni V, Song JH, Gabbay KH, Owerbach D. A M55V polymorphism in a novel SUMO gene (SUMO-4) differentially activates heat shock transcription factors and is associated with susceptibility to type I diabetes mellitus. J Biol Chem. 2004 Jun 25; 279(26):27233-8. PMID: 15123604.
      Citations: 112     Fields:    Translation:HumansCells
    12. Barski OA, Siller-Lopez F, Bohren KM, Gabbay KH, Aguilar-Cordova E. Human aldehyde reductase promoter allows simultaneous expression of two genes in opposite directions. Biotechniques. 2004 Mar; 36(3):382-4, 386, 388. PMID: 15038151.
      Citations:    Fields:    Translation:HumansAnimalsCells
    13. Barski OA, Papusha VZ, Kunkel GR, Gabbay KH. Regulation of aldehyde reductase expression by STAF and CHOP. Genomics. 2004 Jan; 83(1):119-29. PMID: 14667815.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    14. Sheikh-Hamad D, Nadkarni V, Choi YJ, Truong LD, Wideman C, Hodjati R, Gabbay KH. Cyclosporine A inhibits the adaptive responses to hypertonicity: a potential mechanism of nephrotoxicity. J Am Soc Nephrol. 2001 Dec; 12(12):2732-41. PMID: 11729242.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    15. Barski OA, Gabbay KH, Bohren KM. Characterization of the human aldehyde reductase gene and promoter. Genomics. 1999 Sep 01; 60(2):188-98. PMID: 10486210.
      Citations: 6     Fields:    Translation:HumansCells
    16. Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D. Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. J Biol Chem. 1999 Jul 16; 274(29):20185-90. PMID: 10400634.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    17. Burg MB, Peters EM, Bohren KM, Gabbay KH. Factors affecting counteraction by methylamines of urea effects on aldose reductase. Proc Natl Acad Sci U S A. 1999 May 25; 96(11):6517-22. PMID: 10339620.
      Citations: 5     Fields:    Translation:Humans
    18. Harrison DH, Bohren KM, Petsko GA, Ringe D, Gabbay KH. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant. Biochemistry. 1997 Dec 23; 36(51):16134-40. PMID: 9405046.
      Citations: 7     Fields:    Translation:HumansCells
    19. Buhler J, Owerbach D, Schäffer AA, Kimmel M, Gabbay KH. Linkage analyses in type I diabetes mellitus using CASPAR, a software and statistical program for conditional analysis of polygenic diseases. Hum Hered. 1997 Jul-Aug; 47(4):211-22. PMID: 9239508.
      Citations: 2     Fields:    Translation:Humans
    20. Ko BC, Ruepp B, Bohren KM, Gabbay KH, Chung SS. Identification and characterization of multiple osmotic response sequences in the human aldose reductase gene. J Biol Chem. 1997 Jun 27; 272(26):16431-7. PMID: 9195951.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    21. Owerbach D, Naya FJ, Tsai MJ, Allander SV, Powell DR, Gabbay KH. Analysis of candidate genes for susceptibility to type I diabetes: a case-control and family-association study of genes on chromosome 2q31-35. Diabetes. 1997 Jun; 46(6):1069-74. PMID: 9166681.
      Citations: 7     Fields:    Translation:HumansCells
    22. Ruepp BU, Bohren KM, Gabbay KH. Characterization of an element resembling an androgen response element (ARE) in the human aldose reductase promoter. Adv Exp Med Biol. 1997; 414:515-9. PMID: 9059657.
      Citations:    Fields:    Translation:HumansAnimalsCells
    23. Bohren KM, Barski OA, Gabbay KH. Characterization of a novel murine aldo-keto reductase. Adv Exp Med Biol. 1997; 414:455-64. PMID: 9059651.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    24. Barski OA, Gabbay KH, Bohren KM. Aldehyde reductase. Catalytic mechanism and substrate recognition. Adv Exp Med Biol. 1997; 414:443-51. PMID: 9059649.
      Citations:    Fields:    Translation:HumansCells
    25. Barski OA, Gabbay KH, Bohren KM. The C-terminal loop of aldehyde reductase determines the substrate and inhibitor specificity. Biochemistry. 1996 Nov 12; 35(45):14276-80. PMID: 8916913.
      Citations: 16     Fields:    Translation:HumansCells
    26. Ruepp B, Bohren KM, Gabbay KH. Characterization of the osmotic response element of the human aldose reductase gene promoter. Proc Natl Acad Sci U S A. 1996 Aug 06; 93(16):8624-9. PMID: 8710921.
      Citations: 15     Fields:    Translation:HumansCells
    27. Owerbach D, Gabbay KH. The search for IDDM susceptibility genes: the next generation. Diabetes. 1996 May; 45(5):544-51. PMID: 8621001.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    28. Grimshaw CE, Bohren KM, Lai CJ, Gabbay KH. Human aldose reductase: subtle effects revealed by rapid kinetic studies of the C298A mutant enzyme. Biochemistry. 1995 Nov 07; 34(44):14366-73. PMID: 7578040.
      Citations: 6     Fields:    Translation:Humans
    29. Grimshaw CE, Bohren KM, Lai CJ, Gabbay KH. Human aldose reductase: rate constants for a mechanism including interconversion of ternary complexes by recombinant wild-type enzyme. Biochemistry. 1995 Nov 07; 34(44):14356-65. PMID: 7578039.
      Citations: 30     Fields:    Translation:HumansCells
    30. Grimshaw CE, Bohren KM, Lai CJ, Gabbay KH. Human aldose reductase: pK of tyrosine 48 reveals the preferred ionization state for catalysis and inhibition. Biochemistry. 1995 Nov 07; 34(44):14374-84. PMID: 7578041.
      Citations: 12     Fields:    Translation:HumansCells
    31. Barski OA, Gabbay KH, Grimshaw CE, Bohren KM. Mechanism of human aldehyde reductase: characterization of the active site pocket. Biochemistry. 1995 Sep 05; 34(35):11264-75. PMID: 7669785.
      Citations: 18     Fields:    Translation:HumansCells
    32. Owerbach D, Gabbay KH. The HOXD8 locus (2q31) is linked to type I diabetes. Interaction with chromosome 6 and 11 disease susceptibility genes. Diabetes. 1995 Jan; 44(1):132-6. PMID: 7813807.
      Citations: 14     Fields:    Translation:HumansCells
    33. Bohren KM, Wermuth B, Harrison D, Ringe D, Petsko GA, Gabbay KH. Expression, crystallization and preliminary crystallographic analysis of human carbonyl reductase. J Mol Biol. 1994 Dec 16; 244(5):659-64. PMID: 7990149.
      Citations: 3     Fields:    Translation:HumansCells
    34. Ehrig T, Bohren KM, Prendergast FG, Gabbay KH. Mechanism of aldose reductase inhibition: binding of NADP+/NADPH and alrestatin-like inhibitors. Biochemistry. 1994 Jun 14; 33(23):7157-65. PMID: 8003482.
      Citations: 11     Fields:    Translation:Cells
    35. Feke GT, Buzney SM, Ogasawara H, Fujio N, Goger DG, Spack NP, Gabbay KH. Retinal circulatory abnormalities in type 1 diabetes. Invest Ophthalmol Vis Sci. 1994 Jun; 35(7):2968-75. PMID: 8206714.
      Citations: 40     Fields:    Translation:Humans
    36. Owerbach D, Gabbay KH. Linkage of the VNTR/insulin-gene and type I diabetes mellitus: increased gene sharing in affected sibling pairs. Am J Hum Genet. 1994 May; 54(5):909-12. PMID: 7909987.
      Citations: 6     Fields:    Translation:HumansCells
    37. Harrison DH, Bohren KM, Ringe D, Petsko GA, Gabbay KH. An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate. Biochemistry. 1994 Mar 01; 33(8):2011-20. PMID: 8117658.
      Citations: 20     Fields:    Translation:HumansCells
    38. Bohren KM, Grimshaw CE, Lai CJ, Harrison DH, Ringe D, Petsko GA, Gabbay KH. Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry. 1994 Mar 01; 33(8):2021-32. PMID: 8117659.
      Citations: 29     Fields:    Translation:HumansCells
    39. Owerbach D, Gabbay KH. Localization of a type I diabetes susceptibility locus to the variable tandem repeat region flanking the insulin gene. Diabetes. 1993 Dec; 42(12):1708-14. PMID: 8243816.
      Citations: 13     Fields:    Translation:HumansCells
    40. Wang K, Bohren KM, Gabbay KH. Characterization of the human aldose reductase gene promoter. J Biol Chem. 1993 Jul 25; 268(21):16052-8. PMID: 8340427.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    41. Bohren KM, Gabbay KH. Cys298 is responsible for reversible thiol-induced variation in aldose reductase activity. Adv Exp Med Biol. 1993; 328:267-77. PMID: 8493903.
      Citations: 4     Fields:    Translation:HumansCells
    42. Bohren KM, Grimshaw CE, Gabbay KH. Catalytic effectiveness of human aldose reductase. Critical role of C-terminal domain. J Biol Chem. 1992 Oct 15; 267(29):20965-70. PMID: 1400412.
      Citations: 22     Fields:    Translation:HumansCells
    43. Wilson DK, Bohren KM, Gabbay KH, Quiocho FA. An unlikely sugar substrate site in the 1.65 A structure of the human aldose reductase holoenzyme implicated in diabetic complications. Science. 1992 Jul 03; 257(5066):81-4. PMID: 1621098.
      Citations: 81     Fields:    Translation:HumansCells
    44. Bohren KM, Page JL, Shankar R, Henry SP, Gabbay KH. Expression of human aldose and aldehyde reductases. Site-directed mutagenesis of a critical lysine 262. J Biol Chem. 1991 Dec 15; 266(35):24031-7. PMID: 1748675.
      Citations: 25     Fields:    Translation:HumansCells
    45. Rogers DG, Sherman LD, Gabbay KH. Effect of puberty on insulinlike growth factor I and HbA1 in type I diabetes. Diabetes Care. 1991 Nov; 14(11):1031-5. PMID: 1797483.
      Citations: 6     Fields:    Translation:Humans
    46. Owerbach D, Gunn S, Gabbay KH. Multigenic basis for type I diabetes. Association of HRAS1 polymorphism with HLA-DR3, DQw2/DR4, DQw8. Diabetes. 1990 Dec; 39(12):1504-9. PMID: 1978827.
      Citations: 4     Fields:    Translation:HumansCells
    47. Barbetti F, Raben N, Kadowaki T, Cama A, Accili D, Gabbay KH, Merenich JA, Taylor SI, Roth J. Two unrelated patients with familial hyperproinsulinemia due to a mutation substituting histidine for arginine at position 65 in the proinsulin molecule: identification of the mutation by direct sequencing of genomic deoxyribonucleic acid amplified by polymerase chain reaction. J Clin Endocrinol Metab. 1990 Jul; 71(1):164-9. PMID: 2196279.
      Citations: 9     Fields:    Translation:HumansCells
    48. Owerbach D, Gunn S, Gabbay KH. Primary association of HLA-DQw8 with type I diabetes in DR4 patients. Diabetes. 1989 Jul; 38(7):942-5. PMID: 2786821.
      Citations: 12     Fields:    Translation:HumansCells
    49. Bohren KM, Bullock B, Wermuth B, Gabbay KH. The aldo-keto reductase superfamily. cDNAs and deduced amino acid sequences of human aldehyde and aldose reductases. J Biol Chem. 1989 Jun 05; 264(16):9547-51. PMID: 2498333.
      Citations: 70     Fields:    Translation:HumansCells
    50. Wermuth B, Bohren KM, Heinemann G, von Wartburg JP, Gabbay KH. Human carbonyl reductase. Nucleotide sequence analysis of a cDNA and amino acid sequence of the encoded protein. J Biol Chem. 1988 Nov 05; 263(31):16185-8. PMID: 3141401.
      Citations: 22     Fields:    Translation:HumansCells
    51. Owerbach D, Gunn S, Ty G, Wible L, Gabbay KH. Oligonucleotide probes for HLA-DQA and DQB genes define susceptibility to type 1 (insulin-dependent) diabetes mellitus. Diabetologia. 1988 Oct; 31(10):751-7. PMID: 3240836.
      Citations: 10     Fields:    Translation:Humans
    52. Rowe JR, Mickelson EM, Hansen JA, MacDonald MJ, Allen CI, Gabbay KH, Yunis EJ, Sheehy MJ. T-cell-defined DR4 subtypes as markers for type 1 diabetes. Hum Immunol. 1988 May; 22(1):51-60. PMID: 3260586.
      Citations: 3     Fields:    Translation:HumansCells
    53. Wermuth B, Omar A, Forster A, di Francesco C, Wolf M, von Wartburg JP, Bullock B, Gabbay KH. Primary structure of aldehyde reductase from human liver. Prog Clin Biol Res. 1987; 232:297-307. PMID: 3615425.
      Citations: 5     Fields:    Translation:HumansCells
    54. Huff KK, Kaufman D, Gabbay KH, Spencer EM, Lippman ME, Dickson RB. Secretion of an insulin-like growth factor-I-related protein by human breast cancer cells. Cancer Res. 1986 Sep; 46(9):4613-9. PMID: 3731113.
      Citations: 55     Fields:    Translation:Humans
    55. Roberts CT, Brown AL, Graham DE, Seelig S, Berry S, Gabbay KH, Rechler MM. Growth hormone regulates the abundance of insulin-like growth factor I RNA in adult rat liver. J Biol Chem. 1986 Aug 05; 261(22):10025-8. PMID: 3755433.
      Citations: 15     Fields:    Translation:AnimalsCells
    56. Sheehy MJ, Rowe JR, Fuller TC, Yunis EJ, Gabbay KH. A minor subset of HLA-DR3 haplotypes is preferentially increased in type 1 (insulin-dependent) diabetes. Diabetologia. 1985 Dec; 28(12):891-4. PMID: 3937758.
      Citations: 5     Fields:    Translation:HumansCells
    57. Sosenko JM, Miettinen OS, Williamson JR, Gabbay KH. Muscle capillary basement-membrane thickness and long-term glycemia in type I diabetes mellitus. N Engl J Med. 1984 Sep 13; 311(11):694-8. PMID: 6472356.
      Citations: 11     Fields:    Translation:Humans
    58. Raum D, Awdeh Z, Yunis EJ, Alper CA, Gabbay KH. Extended major histocompatibility complex haplotypes in type I diabetes mellitus. J Clin Invest. 1984 Aug; 74(2):449-54. PMID: 6746903.
      Citations: 48     Fields:    Translation:Humans
    59. Sheehy MJ, Quintieri FB, Yang SY, Alosco SM, Matsui Y, Yunis EJ, Gabbay KH. HLA antigens of insulin-dependent diabetics. I. PLT colonies detecting Dw10 and a new class II determinant distinct from HLA-D, DR, MB(DC), MT, and SB. Tissue Antigens. 1984 May; 23(5):290-300. PMID: 6205468.
      Citations: 4     Fields:    Translation:HumansCells
    60. Gabbay KH. [The biochemical basis of the complications of diabetes]. Journ Annu Diabetol Hotel Dieu. 1984; 307-20. PMID: 6443221.
      Citations:    Fields:    Translation:Humans
    61. Jansen M, van Schaik FM, Ricker AT, Bullock B, Woods DE, Gabbay KH, Nussbaum AL, Sussenbach JS, Van den Brande JL. Sequence of cDNA encoding human insulin-like growth factor I precursor. Nature. 1983 Dec 8-14; 306(5943):609-11. PMID: 6358902.
      Citations: 74     Fields:    Translation:HumansCells
    62. Judzewitsch RG, Jaspan JB, Polonsky KS, Weinberg CR, Halter JB, Halar E, Pfeifer MA, Vukadinovic C, Bernstein L, Schneider M, Liang KY, Gabbay KH, Rubenstein AH, Porte D. Aldose reductase inhibition improves nerve conduction velocity in diabetic patients. N Engl J Med. 1983 Jan 20; 308(3):119-25. PMID: 6401351.
      Citations: 41     Fields:    Translation:HumansCellsCTClinical Trials
    63. Sosenko JM, Kitzmiller JL, Fluckiger R, Loo SW, Younger DM, Gabbay KH. Umbilical cord glycosylated hemoglobin in infants of diabetic mothers: relationships to neonatal hypoglycemia, macrosomia, and cord serum C-peptide. Diabetes Care. 1982 Nov-Dec; 5(6):566-70. PMID: 6765511.
      Citations: 4     Fields:    Translation:Humans
    64. Gabbay KH. Glycosylated hemoglobin and diabetes mellitus. Med Clin North Am. 1982 Nov; 66(6):1309-15. PMID: 6755096.
      Citations: 1     Fields:    Translation:Humans
    65. Oyama H, Gabbay K, Loo SW, Hirsch H, Greider M, Permutt A. Radioimmunoassay for catfish pancreatic somatostatin-22. Regul Pept. 1982 May; 3(5-6):383-96. PMID: 6125999.
      Citations: 1     Fields:    Translation:HumansAnimals
    66. Sosenko JM, Breslow J, Miettinen OS, Gabbay KH. Hyperglycemia and plasma lipid levels: covariations in insulin-dependent diabetes. Diabetes Care. 1982 Jan-Feb; 5(1):40-3. PMID: 6958444.
      Citations: 3     Fields:    Translation:Humans
    67. Gallop PM, Flückiger R, Hanneken A, Mininsohn MM, Gabbay KH. Chemical quantitation of hemoglobin glycosylation: fluorometric detection of formaldehyde released upon periodate oxidation of glycoglobin. Anal Biochem. 1981 Nov 01; 117(2):427-32. PMID: 6275744.
      Citations: 9     Fields:    Translation:HumansCells
    68. Foulds G, O'Brien MM, Bianchine JR, Gabbay KH. Kinetics of an orally absorbed aldose reductase inhibitor, sorbinil. Clin Pharmacol Ther. 1981 Nov; 30(5):693-700. PMID: 6794971.
      Citations: 8     Fields:    Translation:Humans
    69. Flückiger R, Harmon W, Meier W, Loo S, Gabbay KH. Hemoglobin carbamylation in uremia. N Engl J Med. 1981 Apr 02; 304(14):823-7. PMID: 7207511.
      Citations: 41     Fields:    Translation:Humans
    70. Steiner DF, Patzelt C, Chan SJ, Quinn PS, Tager HS, Nielsen D, Lernmark A, Noyes BE, Agarwal KL, Gabbay KH, Rubenstein AH. Formation of biologically active peptides. Proc R Soc Lond B Biol Sci. 1980 Oct 29; 210(1178):45-59. PMID: 6107930.
      Citations: 2     Fields:    Translation:Cells
    71. Sosenko JM, Flückiger R, Platt OS, Gabbay KH. Glycosylation of variant hemoglobins in normal and diabetic subjects. Diabetes Care. 1980 Sep-Oct; 3(5):590-3. PMID: 7438977.
      Citations: 3     Fields:    Translation:Humans
    72. Loo SW, Gabbay KH, Merimee TJ. Human pancreatic polypeptide: studies in fasting and in the growth hormone deficient state. Horm Metab Res. 1980 Aug; 12(8):361-3. PMID: 6997163.
      Citations:    Fields:    Translation:Humans
    73. Oyama H, Hirsch HJ, Gabbay KH, Permutt A. Isolation and characterization of immunoreactive somatostatin from fish pancreatic islets. J Clin Invest. 1980 May; 65(5):993-1002. PMID: 6102573.
      Citations:    Fields:    Translation:Animals
    74. Sosenko JM, Breslow JL, Miettinen OS, Gabbay KH. Hyperglycemia and plasma lipid levels: a prospective study of young insulin-dependent diabetic patients. N Engl J Med. 1980 Mar 20; 302(12):650-4. PMID: 6986551.
      Citations: 27     Fields:    Translation:Humans
    75. Gabbay KH. The insulinopathies. N Engl J Med. 1980 Jan 17; 302(3):165-7. PMID: 7350441.
      Citations: 4     Fields:    Translation:Humans
    76. Spitzer JJ, Ferguson JL, Hirsch HJ, Loo S, Gabbay KH. Effects of E coli endotoxin on pancreatic hormones and blood flow. Circ Shock. 1980; 7(4):353-60. PMID: 6112073.
      Citations: 2     Fields:    Translation:AnimalsCells
    77. Sosenko IR, Kitzmiller JL, Loo SW, Blix P, Rubenstein AH, Gabbay KH. The infant of the diabetic mother: correlation of increased cord C-peptide levels with macrosomia and hypoglycemia. N Engl J Med. 1979 Oct 18; 301(16):859-62. PMID: 481527.
      Citations: 12     Fields:    Translation:Humans
    78. Raum D, Alper CA, Stein R, Gabbay KH. Genetic marker for insulin-dependent diabetes mellitus. Lancet. 1979 Jun 09; 1(8128):1208-10. PMID: 87677.
      Citations: 26     Fields:    Translation:HumansCells
    79. Gabbay KH, Bergenstal RM, Wolff J, Mako ME, Rubenstein AH. Familial hyperproinsulinemia: partial characterization of circulating proinsulin-like material. Proc Natl Acad Sci U S A. 1979 Jun; 76(6):2881-5. PMID: 288074.
      Citations: 15     Fields:    Translation:HumansCells
    80. Bunn HF, Shapiro R, McManus M, Garrick L, McDonald MJ, Gallop PM, Gabbay KH. Structural heterogeneity of human hemoglobin A due to nonenzymatic glycosylation. J Biol Chem. 1979 May 25; 254(10):3892-8. PMID: 438166.
      Citations: 38     Fields:    Translation:HumansCells
    81. Gabbay KH, Spack N, Loo S, Hirsch HJ, Ackil AA. Aldose reductase inhibition: studies with alrestatin. Metabolism. 1979 Apr; 28(4 Suppl 1):471-6. PMID: 122298.
      Citations: 10     Fields:    Translation:HumansCells
    82. Gabbay KH, Sosenko JM, Banuchi GA, Mininsohn MJ, Flückiger R. Glycosylated hemoglobins: increased glycosylation of hemoglobin A in diabetic patients. Diabetes. 1979 Apr; 28(4):337-40. PMID: 437373.
      Citations: 29     Fields:    Translation:Humans
    83. Weir GC, Samols E, Loo S, Patel YC, Gabbay KH. Somatostatin and pancreatic polypeptide secretion: effects of glucagon, insulin, and arginine. Diabetes. 1979 Jan; 28(1):35-40. PMID: 759249.
      Citations: 14     Fields:    Translation:Animals
    84. Bunn HF, Gabbay KH, Gallop PM. The glycosylation of hemoglobin: relevance to diabetes mellitus. Science. 1978 Apr 07; 200(4337):21-7. PMID: 635569.
      Citations: 164     Fields:    Translation:Humans
    85. Hirsch HJ, Loo SW, Gabbay KH. The development and regulation of the endocrine pancreas. J Pediatr. 1977 Sep; 91(3):518-20. PMID: 330834.
      Citations:    Fields:    Translation:Humans
    86. Hirsch HJ, Loo S, Evans N, Crigler JF, Filler RM, Gabbay KH. Hypoglycemia of infancy and nesidioblastosis. Studies with somatostatin. N Engl J Med. 1977 Jun 09; 296(23):1323-6. PMID: 193007.
      Citations: 21     Fields:    Translation:Humans
    87. Buzney SM, Frank RN, Varma SD, Tanishima T, Gabbay KH. Aldose reductase in retinal mural cells. Invest Ophthalmol Vis Sci. 1977 May; 16(5):392-6. PMID: 404268.
      Citations: 15     Fields:    Translation:HumansAnimals
    88. Gabbay KH, Hasty K, Breslow JL, Ellison RC, Bunn HF, Gallop PM. Glycosylated hemoglobins and long-term blood glucose control in diabetes mellitus. J Clin Endocrinol Metab. 1977 May; 44(5):859-64. PMID: 858776.
      Citations: 97     Fields:    Translation:HumansCells
    89. Ganda OP, Weir GC, Soeldner JS, Legg MA, Chick WL, Patel YC, Ebeid AM, Gabbay KH, Reichlin S. "Somatostatinoma": a somatostatin-containing tumor of the endocrine pancreas. N Engl J Med. 1977 Apr 28; 296(17):963-7. PMID: 321960.
      Citations: 33     Fields:    Translation:HumansCells
    90. Bergstrom BH, Loo S, Hirsch HJ, Schutzengel D, Gabbay KH. Ultrastructural localization of pancreatic polypeptide in human pancreas. J Clin Endocrinol Metab. 1977 Apr; 44(4):795-8. PMID: 849991.
      Citations: 7     Fields:    Translation:Humans
    91. Gabbay KH. Editorial: Glycosylated hemoglobin and diabetic control. N Engl J Med. 1976 Aug 19; 295(8):443-4. PMID: 934243.
      Citations: 15     Fields:    Translation:Humans
    92. Bunn HF, Haney DN, Kamin S, Gabbay KH, Gallop PM. The biosynthesis of human hemoglobin A1c. Slow glycosylation of hemoglobin in vivo. J Clin Invest. 1976 Jun; 57(6):1652-9. PMID: 932199.
      Citations: 101     Fields:    Translation:HumansCells
    93. Gabbay KH, DeLuca K, Fisher JN, Mako ME, Rubenstein AH. Familial hyperproinsulinemia. An autosomal dominant defect. N Engl J Med. 1976 Apr 22; 294(17):911-5. PMID: 815812.
      Citations: 20     Fields:    Translation:Humans
    94. Bunn HF, Haney DN, Gabbay KH, Gallop PM. Further identification of the nature and linkage of the carbohydrate in hemoglobin A1c. Biochem Biophys Res Commun. 1975 Nov 03; 67(1):103-9. PMID: 1201013.
      Citations: 64     Fields:    Translation:HumansCells
    95. Gabbay KH, Korff J, Schneeberger EE. Vesicular binesis: glucose effect on insulin secretory vesicles. Science. 1975 Jan 17; 187(4172):177-9. PMID: 1089309.
      Citations: 4     Fields:    Translation:AnimalsCells
    96. Gabbay KH, Kinoshita JF. Aldose reductases from mammalian tissues. Methods Enzymol. 1975; 41:159-65. PMID: 1128259.
      Citations:    Fields:    Translation:Animals
    97. Gabbay KH. Hyperglycemia, polyol metabolism, and complications of diabetes mellitus. Annu Rev Med. 1975; 26:521-36. PMID: 238458.
      Citations: 53     Fields:    Translation:HumansAnimals
    98. Gabbay KH, Cathcart ES. Purification and immunologic identification of aldose reductases. Diabetes. 1974 May; 23(5):460-8. PMID: 4830182.
      Citations: 10     Fields:    Translation:AnimalsCells
    99. Dvornik E, Simard-Duquesne N, Krami M, Sestanj K, Gabbay KH, Kinoshita JH, Varma SD, Merola LO. Polyol accumulation in galactosemic and diabetic rats: control by an aldose reductase inhibitor. Science. 1973 Dec 14; 182(4117):1146-8. PMID: 4270794.
      Citations: 30     Fields:    Translation:Animals
    100. Gabbay KH. The sorbitol pathway and the complications of diabetes. N Engl J Med. 1973 Apr 19; 288(16):831-6. PMID: 4266466.
      Citations: 145     Fields:    Translation:HumansAnimalsCells
    101. Gabbay KH. Role of sorbitol pathway in neuropathy. Adv Metab Disord. 1973; 2:Suppl 2:417-32. PMID: 4269012.
      Citations: 8     Fields:    Translation:Animals
    102. Gabbay KH, Kinoshita JH. Mechanism of development and possible prevention of sugar cataracts. Isr J Med Sci. 1972 Aug-Sep; 8(8):1557-61. PMID: 4647820.
      Citations: 6     Fields:    Translation:HumansAnimals
    103. Gabbay KH. Purification and immunological identification of bovine retinal aldose reductase. Isr J Med Sci. 1972 Aug-Sep; 8(8):1626-9. PMID: 4405283.
      Citations: 3     Fields:    Translation:Animals
    104. Colten HR, Gabbay KH. Histamine release from human leukocytes: modulation by a cytochalasin B-sensitive barrier. J Clin Invest. 1972 Jul; 51(7):1927-31. PMID: 4113392.
      Citations: 3     Fields:    Translation:HumansCells
    105. Gabbay KH, Tze WJ. Inhibition of glucose-induced release of insulin by aldose reductase inhibitors. Proc Natl Acad Sci U S A. 1972 Jun; 69(6):1435-9. PMID: 4402538.
      Citations: 14     Fields:    Translation:Animals
    106. Orci L, Gabbay KH, Malaisse WJ. Pancreatic beta-cell web: its possible role in insulin secretion. Science. 1972 Mar 10; 175(4026):1128-30. PMID: 4551150.
      Citations: 117     Fields:    Translation:AnimalsCells
    107. Gabbay KH, Kinoshita JH. Growth hormone, sorbitol, and diabetic capillary disease. Lancet. 1971 May 01; 1(7705):913. PMID: 4102056.
      Citations: 1     Fields:    Translation:Humans
    108. Kinoshita JH, Dvornik D, Kraml M, Gabbay KH. The effect of an aldose reductase inhibitor on the galactose-exposed rabbit lens. Biochim Biophys Acta. 1968 Jun 24; 158(3):472-5. PMID: 5660111.
      Citations: 14     Fields:    Translation:Animals
    109. Gabbay KH, O'Sullivan JB. The sorbitol pathway. Enzyme localization and content in normal and diabetic nerve and cord. Diabetes. 1968 May; 17(5):239-43. PMID: 4384869.
      Citations: 21     Fields:    Translation:AnimalsCells
    110. Gabbay KH, Merola LO, Field RA. Sorbitol pathway: presence in nerve and cord with substrate accumulation in diabetes. Science. 1966 Jan 14; 151(3707):209-10. PMID: 5907911.
      Citations: 71     Fields:    Translation:Animals
    111. SCARPELLI EM, GABBAY KH, KOCHEN JA. LUNG SURFACTANTS, COUNTERIONS, AND HYSTERESIS. Science. 1965 Jun 18; 148(3677):1607-9. PMID: 14287605.
      Citations: 10     Fields:    Translation:AnimalsCells
    112. GABBAY KH, WATERHOUSE C. Paperchromatography of cholesterol esters. J Chromatogr. 1963 Jun; 11:241-6. PMID: 13945978.
      Citations:    Fields:    Translation:Humans
    GABBAY's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (539)
    Explore
    _
    Co-Authors (6)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _