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PUI-KWONG CHAN

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
DivisionPharmacology
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    R01CA042476     (CHAN, PUI-KWONG)Apr 1, 1986 - Feb 28, 1999
    NIH/NCI
    DRUG EFFECTS ON FUNCTION OF PHOSPHOPROTEIN B23
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Chan PK, Zhao M, Che CT, Mak E. Cytotoxic acylated triterpene saponins from the husks of Xanthoceras sorbifolia. J Nat Prod. 2008 Jul; 71(7):1247-50. PMID: 18549275.
      View in: PubMed
    2. Chan PK. Acylation with diangeloyl groups at C21-22 positions in triterpenoid saponins is essential for cytotoxicity towards tumor cells. Biochem Pharmacol. 2007 Feb 01; 73(3):341-50. PMID: 17092489.
      View in: PubMed
    3. Smetana K, Chan PK, Marinov Y, Soucek J, Hrkal Z, Busch H. A short note on the nucleolar size and density in apoptotic leukemic granulocytic precursors (HL-60 cells). Life Sci. 2004 Jul 02; 75(7):791-6. PMID: 15183072.
      View in: PubMed
    4. Chan PK. Inhibition of tumor growth in vitro by the extract of fagopyrum cymosum (fago-c). Life Sci. 2003 Mar 07; 72(16):1851-8. PMID: 12586222.
      View in: PubMed
    5. Chan PK, Bloom DA, Hoang TT. The N-terminal half of NPM dissociates from nucleoli of HeLa cells after anticancer drug treatments. Biochem Biophys Res Commun. 1999 Oct 14; 264(1):305-9. PMID: 10527882.
      View in: PubMed
    6. Chan PK, Chan FY. A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin. Biochem Pharmacol. 1999 Jun 01; 57(11):1265-73. PMID: 10230770.
      View in: PubMed
    7. Finch RA, Revankar GR, Chan PK. Structural and functional relationships of toyocamycin on NPM-translocation. Anticancer Drug Des. 1997 Apr; 12(3):205-15. PMID: 9154111.
      View in: PubMed
    8. Chan PK, Chan FY, Morris SW, Xie Z. Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer region. Nucleic Acids Res. 1997 Mar 15; 25(6):1225-32. PMID: 9092633.
      View in: PubMed
    9. Finch RA, Chan PK. ATP depletion affects NPM translocation and exportation of rRNA from nuclei. Biochem Biophys Res Commun. 1996 May 15; 222(2):553-8. PMID: 8670243.
      View in: PubMed
    10. Chan PK, Qi Y, Amley J, Koller CA. Quantitation of the nucleophosmin/B23-translocation using imaging analysis. Cancer Lett. 1996 Feb 27; 100(1-2):191-7. PMID: 8620441.
      View in: PubMed
    11. Finch RA, Chang DC, Chan PK. GTP gamma S restores nucleophosmin (NPM) localization to nucleoli of GTP-depleted HeLa cells. Mol Cell Biochem. 1995 May 24; 146(2):171-8. PMID: 7565647.
      View in: PubMed
    12. Chan PK, Chan FY. Nucleophosmin/B23 (NPM) oligomer is a major and stable entity in HeLa cells. Biochim Biophys Acta. 1995 May 17; 1262(1):37-42. PMID: 7772597.
      View in: PubMed
    13. Valdez BC, Perlaky L, Henning D, Saijo Y, Chan PK, Busch H. Identification of the nuclear and nucleolar localization signals of the protein p120. Interaction with translocation protein B23. J Biol Chem. 1994 Sep 23; 269(38):23776-83. PMID: 8089149.
      View in: PubMed
    14. Finch RA, Revankar GR, Chan PK. Nucleolar localization of nucleophosmin/B23 requires GTP. J Biol Chem. 1993 Mar 15; 268(8):5823-7. PMID: 8095498.
      View in: PubMed
    15. Liu QR, Chan PK. Characterization of seven processed pseudogenes of nucleophosmin/B23 in the human genome. DNA Cell Biol. 1993 Mar; 12(2):149-56. PMID: 8471164.
      View in: PubMed
    16. Chan PK. Characterization and cellular localization of nucleophosmin/B23 in HeLa cells treated with selected cytotoxic agents (studies of B23-translocation mechanism). Exp Cell Res. 1992 Nov; 203(1):174-81. PMID: 1426041.
      View in: PubMed
    17. Finch RA, Chan PK. Studies of actinomycin D induced B23-translocation in P388D1 cells implanted in DBA/2 mice. Oncology. 1992; 49(3):223-6. PMID: 1495750.
      View in: PubMed
    18. Liu QR, Chan PK. Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein. Eur J Biochem. 1991 Sep 15; 200(3):715-21. PMID: 1915343.
      View in: PubMed
    19. Chan PK, Liu QR, Durban E. The major phosphorylation site of nucleophosmin (B23) is phosphorylated by a nuclear kinase II. Biochem J. 1990 Sep 01; 270(2):549-52. PMID: 2400401.
      View in: PubMed
    20. Liu QR, Chan PK. Identification of a long stretch of homopurine.homopyrimidine sequence in a cluster of retroposons in the human genome. J Mol Biol. 1990 Apr 05; 212(3):453-9. PMID: 2157848.
      View in: PubMed
    21. Chan PK. Cross-linkage of nucleophosmin in tumor cells by nitrogen mustard. Cancer Res. 1989 Jun 15; 49(12):3271-5. PMID: 2720680.
      View in: PubMed
    22. Chan PK, Aldrich MB, Chakrabarty S. Assessment of tumor cell sensitivity to mitomycin C by "B23 translocation" assay. Cancer Lett. 1988 Jun 15; 40(2):143-9. PMID: 3133107.
      View in: PubMed
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