InstitutionBaylor College of Medicine
DepartmentDepartment of Pharmacology and Chemical Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    R01CA042476     (CHAN, PUI-KWONG)Apr 1, 1986 - Feb 28, 1999
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Chan PK, Zhao M, Che CT, Mak E. Cytotoxic acylated triterpene saponins from the husks of Xanthoceras sorbifolia. J Nat Prod. 2008 Jul; 71(7):1247-50. PMID: 18549275.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    2. Chan PK. Acylation with diangeloyl groups at C21-22 positions in triterpenoid saponins is essential for cytotoxicity towards tumor cells. Biochem Pharmacol. 2007 Feb 01; 73(3):341-50. PMID: 17092489.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    3. Chan PK. Inhibition of tumor growth in vitro by the extract of fagopyrum cymosum (fago-c). Life Sci. 2003 Mar 07; 72(16):1851-8. PMID: 12586222.
      Citations: 15     Fields:    Translation:HumansCells
    4. Chan PK, Bloom DA, Hoang TT. The N-terminal half of NPM dissociates from nucleoli of HeLa cells after anticancer drug treatments. Biochem Biophys Res Commun. 1999 Oct 14; 264(1):305-9. PMID: 10527882.
      Citations: 6     Fields:    Translation:HumansCells
    5. Chan PK, Chan FY. A study of correlation between NPM-translocation and apoptosis in cells induced by daunomycin. Biochem Pharmacol. 1999 Jun 01; 57(11):1265-73. PMID: 10230770.
      Citations: 8     Fields:    Translation:HumansCells
    6. Finch RA, Revankar GR, Chan PK. Structural and functional relationships of toyocamycin on NPM-translocation. Anticancer Drug Des. 1997 Apr; 12(3):205-15. PMID: 9154111.
      Citations: 3     Fields:    Translation:HumansCells
    7. Chan PK, Chan FY, Morris SW, Xie Z. Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer region. Nucleic Acids Res. 1997 Mar 15; 25(6):1225-32. PMID: 9092633; PMCID: PMC146576.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    8. Finch RA, Chan PK. ATP depletion affects NPM translocation and exportation of rRNA from nuclei. Biochem Biophys Res Commun. 1996 May 15; 222(2):553-8. PMID: 8670243.
      Citations: 10     Fields:    Translation:HumansCells
    9. Chan PK, Qi Y, Amley J, Koller CA. Quantitation of the nucleophosmin/B23-translocation using imaging analysis. Cancer Lett. 1996 Feb 27; 100(1-2):191-7. PMID: 8620441.
      Citations: 15     Fields:    Translation:HumansCells
    10. Finch RA, Chang DC, Chan PK. GTP gamma S restores nucleophosmin (NPM) localization to nucleoli of GTP-depleted HeLa cells. Mol Cell Biochem. 1995 May 24; 146(2):171-8. PMID: 7565647.
      Citations: 4     Fields:    Translation:HumansCells
    11. Chan PK, Chan FY. Nucleophosmin/B23 (NPM) oligomer is a major and stable entity in HeLa cells. Biochim Biophys Acta. 1995 May 17; 1262(1):37-42. PMID: 7772597.
      Citations: 15     Fields:    Translation:HumansCells
    12. Valdez BC, Perlaky L, Henning D, Saijo Y, Chan PK, Busch H. Identification of the nuclear and nucleolar localization signals of the protein p120. Interaction with translocation protein B23. J Biol Chem. 1994 Sep 23; 269(38):23776-83. PMID: 8089149.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    13. Finch RA, Revankar GR, Chan PK. Nucleolar localization of nucleophosmin/B23 requires GTP. J Biol Chem. 1993 Mar 15; 268(8):5823-7. PMID: 8095498.
      Citations: 11     Fields:    Translation:HumansCells
    14. Liu QR, Chan PK. Characterization of seven processed pseudogenes of nucleophosmin/B23 in the human genome. DNA Cell Biol. 1993 Mar; 12(2):149-56. PMID: 8471164.
      Citations: 4     Fields:    Translation:HumansCells
    15. Chan PK. Characterization and cellular localization of nucleophosmin/B23 in HeLa cells treated with selected cytotoxic agents (studies of B23-translocation mechanism). Exp Cell Res. 1992 Nov; 203(1):174-81. PMID: 1426041.
      Citations: 24     Fields:    Translation:HumansCells
    16. Finch RA, Chan PK. Studies of actinomycin D induced B23-translocation in P388D1 cells implanted in DBA/2 mice. Oncology. 1992; 49(3):223-6. PMID: 1495750.
      Citations: 1     Fields:    Translation:AnimalsCells
    17. Liu QR, Chan PK. Formation of nucleophosmin/B23 oligomers requires both the amino- and the carboxyl-terminal domains of the protein. Eur J Biochem. 1991 Sep 15; 200(3):715-21. PMID: 1915343.
      Citations: 14     Fields:    Translation:HumansCells
    18. Chan PK, Liu QR, Durban E. The major phosphorylation site of nucleophosmin (B23) is phosphorylated by a nuclear kinase II. Biochem J. 1990 Sep 01; 270(2):549-52. PMID: 2400401; PMCID: PMC1131759.
      Citations: 12     Fields:    Translation:HumansCells
    19. Liu QR, Chan PK. Identification of a long stretch of homopurine.homopyrimidine sequence in a cluster of retroposons in the human genome. J Mol Biol. 1990 Apr 05; 212(3):453-9. PMID: 2157848.
      Citations: 7     Fields:    Translation:HumansCells
    20. Chan PK. Cross-linkage of nucleophosmin in tumor cells by nitrogen mustard. Cancer Res. 1989 Jun 15; 49(12):3271-5. PMID: 2720680.
      Citations: 9     Fields:    Translation:AnimalsCells
    21. Chan PK, Aldrich MB, Chakrabarty S. Assessment of tumor cell sensitivity to mitomycin C by "B23 translocation" assay. Cancer Lett. 1988 Jun 15; 40(2):143-9. PMID: 3133107.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
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