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DEBORAH PINSON HYINK

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Nephrology
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    F32DK009615     (HYINK, DEBORAH P)Mar 5, 1997
    NIH/NIDDK
    MOLECULAR CONTROL OF RENAL EPITHELIAL DIFFERENTIATION
    Role: Principal Investigator

    K01DK002783     (HYINK, DEBORAH P)Sep 30, 2000 - Jul 31, 2004
    NIH/NIDDK
    MULTIPOTENT PROGENITOR CELLS IN THE KIDNEY
    Role: Principal Investigator

    R21DK065836     (HYINK, DEBORAH P)Dec 1, 2003 - Nov 30, 2006
    NIH/NIDDK
    Modeling renal development
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Li H, Zhang W, Zhong F, Das GC, Xie Y, Li Z, Cai W, Jiang G, Choi J, Sidani M, Hyink DP, Lee K, Klotman PE, He JC. Epigenetic regulation of RCAN1 expression in kidney disease and its role in podocyte injury. Kidney Int. 2018 12; 94(6):1160-1176. PMID: 30366682.
      View in: PubMed
    2. Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE. Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte. PLoS One. 2014; 9(6):e100660. PMID: 24949636.
      View in: PubMed
    3. Sharma M, Magenheimer LK, Home T, Tamano KN, Singhal PC, Hyink DP, Klotman PE, Vanden Heuvel GB, Fields TA. Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy. Am J Physiol Renal Physiol. 2013 Apr 15; 304(8):F1127-36. PMID: 23389453.
      View in: PubMed
    4. Hays T, D'Agati VD, Garellek JA, Warren T, Trubin ME, Hyink DP, He JC, Klotman PE. Glomerular MYH9 expression is reduced by HIV-1. AIDS. 2012 Apr 24; 26(7):797-803. PMID: 22313957.
      View in: PubMed
    5. Hyink D. Three-dimensional imaging of fetal mouse kidneys. Methods Mol Biol. 2012; 886:87-93. PMID: 22639253.
      View in: PubMed
    6. Li X, Iomini C, Hyink D, Wilson PD. PRKX critically regulates endothelial cell proliferation, migration, and vascular-like structure formation. Dev Biol. 2011 Aug 15; 356(2):475-85. PMID: 21684272.
      View in: PubMed
    7. Boucher CA, Ward HH, Case RL, Thurston KS, Li X, Needham A, Romero E, Hyink D, Qamar S, Roitbak T, Powell S, Ward C, Wilson PD, Wandinger-Ness A, Sandford RN. Receptor protein tyrosine phosphatases are novel components of a polycystin complex. Biochim Biophys Acta. 2011 Oct; 1812(10):1225-38. PMID: 21126580.
      View in: PubMed
    8. Kuure S, Cebrian C, Machingo Q, Lu BC, Chi X, Hyink D, D'Agati V, Gurniak C, Witke W, Costantini F. Actin depolymerizing factors cofilin1 and destrin are required for ureteric bud branching morphogenesis. PLoS Genet. 2010 Oct 28; 6(10):e1001176. PMID: 21060807.
      View in: PubMed
    9. Michos O, Cebrian C, Hyink D, Grieshammer U, Williams L, D'Agati V, Licht JD, Martin GR, Costantini F. Kidney development in the absence of Gdnf and Spry1 requires Fgf10. PLoS Genet. 2010 Jan 15; 6(1):e1000809. PMID: 20084103.
      View in: PubMed
    10. Villarroya J, Diaz-Delfin J, Hyink D, Domingo P, Giralt M, Klotman PE, Villarroya F. HIV type-1 transgene expression in mice alters adipose tissue and adipokine levels: towards a rodent model of HIV type-1 lipodystrophy. Antivir Ther. 2010; 15(7):1021-8. PMID: 21041917.
      View in: PubMed
    11. Feng X, Lu TC, Chuang PY, Fang W, Ratnam K, Xiong H, Ouyang X, Shen Y, Levy DE, Hyink D, Klotman M, D'Agati V, Iyengar R, Klotman PE, He JC. Reduction of Stat3 activity attenuates HIV-induced kidney injury. J Am Soc Nephrol. 2009 Oct; 20(10):2138-46. PMID: 19608706.
      View in: PubMed
    12. Li X, Hyink DP, Radbill B, Sudol M, Zhang H, Zheleznova NN, Wilson PD. Protein kinase-X interacts with Pin-1 and Polycystin-1 during mouse kidney development. Kidney Int. 2009 Jul; 76(1):54-62. PMID: 19367327.
      View in: PubMed
    13. Chi X, Hadjantonakis AK, Wu Z, Hyink D, Costantini F. A transgenic mouse that reveals cell shape and arrangement during ureteric bud branching. Genesis. 2009 Feb; 47(2):61-6. PMID: 19111008.
      View in: PubMed
    14. Li X, Burrow CR, Polgar K, Hyink DP, Gusella GL, Wilson PD. Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency. Biochim Biophys Acta. 2008 Jan; 1782(1):1-9. PMID: 17980165.
      View in: PubMed
    15. Vigneau C, Polgar K, Striker G, Elliott J, Hyink D, Weber O, Fehling HJ, Keller G, Burrow C, Wilson P. Mouse embryonic stem cell-derived embryoid bodies generate progenitors that integrate long term into renal proximal tubules in vivo. J Am Soc Nephrol. 2007 Jun; 18(6):1709-20. PMID: 17475814.
      View in: PubMed
    16. Basson MA, Watson-Johnson J, Shakya R, Akbulut S, Hyink D, Costantini FD, Wilson PD, Mason IJ, Licht JD. Branching morphogenesis of the ureteric epithelium during kidney development is coordinated by the opposing functions of GDNF and Sprouty1. Dev Biol. 2006 Nov 15; 299(2):466-77. PMID: 17022962.
      View in: PubMed
    17. Wilson SJ, Amsler K, Hyink DP, Li X, Lu W, Zhou J, Burrow CR, Wilson PD. Inhibition of HER-2(neu/ErbB2) restores normal function and structure to polycystic kidney disease (PKD) epithelia. Biochim Biophys Acta. 2006 Jul; 1762(7):647-55. PMID: 16797938.
      View in: PubMed
    18. Clendenon JL, Byars JM, Hyink DP. Image processing software for 3D light microscopy. Nephron Exp Nephrol. 2006; 103(2):e50-4. PMID: 16543764.
      View in: PubMed
    19. Li X, Hyink DP, Polgar K, Gusella GL, Wilson PD, Burrow CR. Protein kinase X activates ureteric bud branching morphogenesis in developing mouse metanephric kidney. J Am Soc Nephrol. 2005 Dec; 16(12):3543-52. PMID: 16236808.
      View in: PubMed
    20. Polgar K, Burrow CR, Hyink DP, Fernandez H, Thornton K, Li X, Gusella GL, Wilson PD. Disruption of polycystin-1 function interferes with branching morphogenesis of the ureteric bud in developing mouse kidneys. Dev Biol. 2005 Oct 01; 286(1):16-30. PMID: 16122726.
      View in: PubMed
    21. Qiu L, Hyink DP, Gans WH, Amsler K, Wilson PD, Burrow CR. Midkine promotes selective expansion of the nephrogenic mesenchyme during kidney organogenesis. Organogenesis. 2004 Jul; 1(1):14-21. PMID: 19521555.
      View in: PubMed
    22. Gross I, Morrison DJ, Hyink DP, Georgas K, English MA, Mericskay M, Hosono S, Sassoon D, Wilson PD, Little M, Licht JD. The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development. J Biol Chem. 2003 Oct 17; 278(42):41420-30. PMID: 12882970.
      View in: PubMed
    23. Kaletta T, Van der Craen M, Van Geel A, Dewulf N, Bogaert T, Branden M, King KV, Buechner M, Barstead R, Hyink D, Li HP, Geng L, Burrow C, Wilson P. Towards understanding the polycystins. Nephron Exp Nephrol. 2003 Jan; 93(1):e9-17. PMID: 12411744.
      View in: PubMed
    24. Li X, Li HP, Amsler K, Hyink D, Wilson PD, Burrow CR. PRKX, a phylogenetically and functionally distinct cAMP-dependent protein kinase, activates renal epithelial cell migration and morphogenesis. Proc Natl Acad Sci U S A. 2002 Jul 09; 99(14):9260-5. PMID: 12082174.
      View in: PubMed
    25. Hyink DP, Rappoport JZ, Wilson PD, Abramson RG. Expression of the urate transporter/channel is developmentally regulated in human kidneys. Am J Physiol Renal Physiol. 2001 Nov; 281(5):F875-86. PMID: 11592946.
      View in: PubMed
    26. Hosono S, Luo X, Hyink DP, Schnapp LM, Wilson PD, Burrow CR, Reddy JC, Atweh GF, Licht JD. WT1 expression induces features of renal epithelial differentiation in mesenchymal fibroblasts. Oncogene. 1999 Jan 14; 18(2):417-27. PMID: 9927198.
      View in: PubMed
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