Header Logo

KRITHIKA LINGAPPAN

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address
vCardDownload vCard

    Collapse Biography 
    Collapse awards and honors
    2011AAP Young Investigator Award, The American Academy of Pediatrics, Section on Perinatal Pediatrics
    2012SSPR Young Investigator Award, Southern Society of Pediatric Research
    2012The Arnold J.Rudolph Award, Baylor College of Medicine
    2015SSPR Young Faculty Award, Southern Society of Pediatric Research
    2016SSPR Young Faculty Award, Southern Society of Pediatric research
    2017SSPR Young Faculty Award, Southern Society of Pediatric research
    2019Young Investigator Award, Department of Pediatrics, Baylor College of Medicine
    2019Norton Rose Fulbright Award for Teaching and Evaluation, Baylor College of Medicine
    2019Woman of Excellence Award, Baylor College of Medcine
    2020 - 2024Leveraging multi-omics and advanced mouse models to delineate mechanisms underlying sex-specific dif, NHLBI
    2019 - 2024Mechanisms of sex differences in neonatal pulmonary oxygen toxicity , NHLBI

    Collapse Overview 
    Collapse overview
    My research focuses on reducing long term morbidities such as chronic lung disease (bronchopulmonary dysplasia) in premature babies. Specifically, our research focises on the elucidating the mechanisms behind sex-specific differences in the incidence of BPD. In the future, this research should lead to therapeutic lung-protective strategies. There is a great need for such therapeutic strategies to improve outcomes in premature babies, given that the incidence of BPD in premature neonates has been reported to be as high as 50%. The long-term goal of this research is to develop new translational strategies, both therapeutic and diagnostic in the field of neonatal lung injury.

    Collapse Research 
    Collapse research activities and funding
    R21HD100862     (LINGAPPAN, KRITHIKA)Jun 23, 2020 - May 31, 2022
    NIH
    Sex as biological variable in Bronchopulmonary Dysplasia: Role of the Notch pathway
    Role: Principal Investigator
    R01HL146395     (LINGAPPAN, KRITHIKA)May 15, 2020 - Apr 30, 2024
    NIH
    Leveraging multiomics and advanced mouse models to delineate mechanisms underlying sex?specific differences in recovery and repair after neonatal hyperoxia exposure in the developing lung
    Role: Principal Investigator
    R01HL144775     (LINGAPPAN, KRITHIKA)Jul 1, 2019 - Jun 30, 2024
    NIH
    Mechanisms of sex differences in neonatal pulmonary oxygen toxicity
    Role: Principal Investigator
    R03HL141572     (LINGAPPAN, KRITHIKA)May 5, 2018 - Apr 30, 2020
    NIH
    Sex-specific differences in neonatal hyperoxic lung injury: Role of the NF-kappa B pathway
    Role: Principal Investigator
    K08HL127103     (LINGAPPAN, KRITHIKA)May 1, 2015 - Apr 30, 2020
    NIH
    Mechanisms of sex specific differences in neonatal hyperoxic lung injury
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lingappan K, Alur P, Eichenwald E, Lingappan K, Alur P, Eichenwald E. The Need to Address Sex as a Biological Variable in Neonatal Clinical Studies. J Pediatr. 2022 Nov 30. PMID: 36460079.
      Citations:    
    2. Hayward-Piatkovskyi B, Gonyea CR, Pyle SC, Lingappan K, Gleghorn JP. Sex-related external factors influence pulmonary vascular angiogenesis in a sex-dependent manner. Am J Physiol Heart Circ Physiol. 2023 01 01; 324(1):H26-H32. PMID: 36367696; PMCID: PMC9762957.
      Citations:    
    3. Machut KZ, Bhombal S, Escobedo M, Kataria-Hale J, Kushnir A, Lingappan K, Oji-Mmuo CN, Owens L, Savich R, Song C, Wright R, Dammann CEL. Correction to: Call to action: gender equity in neonatology. J Perinatol. 2022 Nov; 42(11):1560. PMID: 36195622.
      Citations:    
    4. Cantu A, Gutierrez MC, Dong X, Leek C, Sajti E, Lingappan K. Remarkable sex-specific differences at single-cell resolution in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2023 01 01; 324(1):L5-L31. PMID: 36283964; PMCID: PMC9799156.
      Citations:    
    5. Almudares F, Hagan J, Chen X, Devaraj S, Moorthy B, Lingappan K. Growth and differentiation factor 15 (GDF15) levels predict adverse respiratory outcomes in premature neonates. Pediatr Pulmonol. 2023 01; 58(1):271-278. PMID: 36205439; PMCID: PMC9772066.
      Citations:    
    6. Olutoye Ii OO, Short WD, Gilley J, Hammond Ii JD, Belfort MA, Lee TC, King A, Espinoza J, Joyeux L, Lingappan K, Gleghorn JP, Keswani SG, Olutoye Ii OO, Short WD, Gilley J, Hammond Ii JD, Belfort MA, Lee TC, King A, Espinoza J, Joyeux L, Lingappan K, Gleghorn JP, Keswani SG. The Cellular and Molecular Effects of Fetoscopic Endoluminal Tracheal Occlusion in Congenital Diaphragmatic Hernia. Front Pediatr. 2022; 10:925106. PMID: 35865706; PMCID: PMC9294219.
      Citations:    
    7. Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI, Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI. Correction to: Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal ?-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants. Toxicol Sci. 2022 Apr 26; 187(1):187. PMID: 35348789; PMCID: PMC9216002.
      Citations:    Fields:    
    8. Machut KZ, Bhombal S, Escobedo M, Kataria-Hale J, Kushnir A, Lingappan K, Oji-Mmuo CN, Owens L, Savich R, Song C, Wright R, Dammann CEL, Machut KZ, Bhombal S, Escobedo M, Kataria-Hale J, Kushnir A, Lingappan K, Oji-Mmuo CN, Owens L, Savich R, Song C, Wright R, Dammann CEL. Call to action: gender equity in neonatology. J Perinatol. 2022 07; 42(7):982-983. PMID: 35411019.
      Citations:    Fields:    Translation:Humans
    9. Chumpitazi CE, Camp EA, Cuevas-Guaman M, Doughty C, Kancherla B, Lingappan K, Moran NE, Murray KO, Perez O, Shekerdemian LS, O'Connor TM, Chumpitazi CE, Camp EA, Cuevas-Guaman M, Doughty C, Kancherla B, Lingappan K, Moran NE, Murray KO, Perez O, Shekerdemian LS, O'Connor TM. Vision 2020: How Caregiving and Work Productivity Outlook Shifted for Academic Pediatric Faculty. J Womens Health (Larchmt). 2022 05; 31(5):631-639. PMID: 35167379.
      Citations:    Fields:    Translation:HumansPHPublic Health
    10. Machut KZ, Kushnir A, Oji-Mmuo CN, Kataria-Hale J, Lingappan K, Kwon S, Dammann CEL, Machut KZ, Kushnir A, Oji-Mmuo CN, Kataria-Hale J, Lingappan K, Kwon S, Dammann CEL. Effect of Coronavirus Disease-2019 on the Workload of Neonatologists. J Pediatr. 2022 Mar; 242:145-151.e1. PMID: 34748740; PMCID: PMC8572527.
      Citations:    Fields:    Translation:HumansCells
    11. Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy B, Burke R, Chu C, Zhou GD, Putluri V, Putluri N, Stading RE, Couroucli X, Lingappan K, Moorthy B. Role of Human NADPH Quinone Oxidoreductase (NQO1) in Oxygen-Mediated Cellular Injury and Oxidative DNA Damage in Human Pulmonary Cells. Oxid Med Cell Longev. 2021; 2021:5544600. PMID: 34691356; PMCID: PMC8536466.
      Citations: 1     Fields:    Translation:Humans
    12. Lingappan K, Lingappan K. Does the Epigenome Hold Clues to Leptin-associated Hypertension in Obesity? Am J Respir Cell Mol Biol. 2021 08; 65(2):132-133. PMID: 34029509; PMCID: PMC8399570.
      Citations: 1     Fields:    Translation:Humans
    13. Koo J, Lingappan K, Song C, Koo J, Lingappan K, Song C. National professional society augments career development and leadership amongst neonatal fellows and early career neonatologists. J Perinatol. 2022 04; 42(4):546-549. PMID: 34294879.
      Citations:    Fields:    Translation:Humans
    14. Grimm SL, Dong X, Zhang Y, Carisey AF, Arnold AP, Moorthy B, Coarfa C, Lingappan K, Grimm SL, Dong X, Zhang Y, Carisey AF, Arnold AP, Moorthy B, Coarfa C, Lingappan K. Effect of sex chromosomes versus hormones in neonatal lung injury. JCI Insight. 2021 07 08; 6(13). PMID: 34061778; PMCID: PMC8410054.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    15. Jain PN, Robertson M, Lasa JJ, Shekerdemian L, Guffey D, Zhang Y, Lingappan K, Checchia P, Coarfa C, Jain PN, Robertson M, Lasa JJ, Shekerdemian L, Guffey D, Zhang Y, Lingappan K, Checchia P, Coarfa C. Altered metabolic and inflammatory transcriptomics after cardiac surgery in neonates with congenital heart disease. Sci Rep. 2021 03 02; 11(1):4965. PMID: 33654130; PMCID: PMC7925649.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    16. Stading R, Couroucli X, Lingappan K, Moorthy B, Stading R, Couroucli X, Lingappan K, Moorthy B. The role of cytochrome P450 (CYP) enzymes in hyperoxic lung injury. Expert Opin Drug Metab Toxicol. 2021 Feb; 17(2):171-178. PMID: 33215946; PMCID: PMC7864879.
      Citations: 4     Fields:    Translation:HumansAnimals
    17. Al-Mudares F, Reddick S, Ren J, Venkatesh A, Zhao C, Lingappan K, Al-Mudares F, Reddick S, Ren J, Venkatesh A, Zhao C, Lingappan K. Role of Growth Differentiation Factor 15 in Lung Disease and Senescence: Potential Role Across the Lifespan. Front Med (Lausanne). 2020; 7:594137. PMID: 33344478; PMCID: PMC7744305.
      Citations: 2     
    18. Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker CL, Moorthy B, Lingappan K, Coarfa C, Grimm SL, Katz T, Zhang Y, Jangid RK, Walker CL, Moorthy B, Lingappan K. Epigenetic response to hyperoxia in the neonatal lung is sexually dimorphic. Redox Biol. 2020 10; 37:101718. PMID: 32961439; PMCID: PMC7509469.
      Citations: 8     Fields:    Translation:Animals
    19. Callaway DA, Jiang W, Wang L, Lingappan K, Moorthy B, Callaway DA, Jiang W, Wang L, Lingappan K, Moorthy B. Oxygen-mediated lung injury in mice lacking the gene for NRF2: Rescue with the cytochrome P4501A-inducer, beta-naphthoflavone (BNF), and differential sex-specific effects. Free Radic Biol Med. 2020 11 20; 160:208-218. PMID: 32791187; PMCID: PMC7704914.
      Citations: 3     Fields:    Translation:HumansAnimals
    20. Stading R, Chu C, Couroucli X, Lingappan K, Moorthy B, Stading R, Chu C, Couroucli X, Lingappan K, Moorthy B. Molecular role of cytochrome P4501A enzymes inoxidative stress. Curr Opin Toxicol. 2020 Apr-Jun; 20-21:77-84. PMID: 33283080; PMCID: PMC7709944.
      Citations: 2     
    21. Lingappan K, Karmouty-Quintana H, Davies J, Akkanti B, Harting MT, Lingappan K, Karmouty-Quintana H, Davies J, Akkanti B, Harting MT. Understanding the age divide in COVID-19: why are children overwhelmingly spared? Am J Physiol Lung Cell Mol Physiol. 2020 07 01; 319(1):L39-L44. PMID: 32491949; PMCID: PMC7324935.
      Citations: 42     Fields:    Translation:HumansCellsPHPublic Health
    22. Lingappan K, Savani RC, Lingappan K, Savani RC. The Wnt Signaling Pathway and the Development of Bronchopulmonary Dysplasia. Am J Respir Crit Care Med. 2020 05 15; 201(10):1174-1176. PMID: 32101467; PMCID: PMC7233338.
      Citations: 6     Fields:    Translation:HumansCells
    23. Zhang Y, Dong X, Lingappan K, Zhang Y, Dong X, Lingappan K. Role of HIF-1a-miR30a-Snai1 Axis in Neonatal Hyperoxic Lung Injury. Oxid Med Cell Longev. 2019; 2019:8327486. PMID: 31772711; PMCID: PMC6854945.
      Citations: 7     Fields:    Translation:HumansAnimals
    24. Althouse MH, Stewart C, Jiang W, Moorthy B, Lingappan K, Althouse MH, Stewart C, Jiang W, Moorthy B, Lingappan K. Impact of Early Life Antibiotic Exposure and Neonatal Hyperoxia on the Murine Microbiome and Lung Injury. Sci Rep. 2019 10 18; 9(1):14992. PMID: 31628395; PMCID: PMC6802223.
      Citations: 4     Fields:    Translation:Animals
    25. Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou G, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B, Suter MA, Aagaard KM, Coarfa C, Robertson M, Zhou G, Jackson BP, Thompson D, Putluri V, Putluri N, Hagan J, Wang L, Jiang W, Lingappan K, Moorthy B. Association between elevated placental polycyclic aromatic hydrocarbons (PAHs) and PAH-DNA adducts from Superfund sites in Harris County, and increased risk of preterm birth (PTB). Biochem Biophys Res Commun. 2019 08 20; 516(2):344-349. PMID: 31208719; PMCID: PMC6637943.
      Citations: 13     Fields:    Translation:HumansPHPublic Health
    26. Zhang Y, Coarfa C, Dong X, Jiang W, Hayward-Piatkovskyi B, Gleghorn JP, Lingappan K, Zhang Y, Coarfa C, Dong X, Jiang W, Hayward-Piatkovskyi B, Gleghorn JP, Lingappan K. MicroRNA-30a as a candidate underlying sex-specific differences in neonatal hyperoxic lung injury: implications for BPD. Am J Physiol Lung Cell Mol Physiol. 2019 01 01; 316(1):L144-L156. PMID: 30382766; PMCID: PMC6383497.
      Citations: 7     Fields:    Translation:AnimalsCells
    27. Veith AC, Bou Aram B, Jiang W, Wang L, Zhou G, Jefcoate CR, Couroucli XI, Lingappan K, Moorthy B, Veith AC, Bou Aram B, Jiang W, Wang L, Zhou G, Jefcoate CR, Couroucli XI, Lingappan K, Moorthy B. Mice Lacking the Cytochrome P450 1B1 Gene Are Less Susceptible to Hyperoxic Lung Injury Than Wild Type. Toxicol Sci. 2018 10 01; 165(2):462-474. PMID: 29939353; PMCID: PMC6154276.
      Citations: 7     Fields:    Translation:AnimalsCells
    28. Balaji S, Dong X, Li H, Zhang Y, Steen E, Lingappan K, Balaji S, Dong X, Li H, Zhang Y, Steen E, Lingappan K. Sex-specific differences in primary neonatal murine lung fibroblasts exposed to hyperoxia in vitro: implications for bronchopulmonary dysplasia. Physiol Genomics. 2018 11 01; 50(11):940-946. PMID: 30169132; PMCID: PMC6293119.
      Citations: 4     Fields:    Translation:AnimalsCells
    29. Zhang Y, Dong X, Shirazi J, Gleghorn JP, Lingappan K, Zhang Y, Dong X, Shirazi J, Gleghorn JP, Lingappan K. Pulmonary endothelial cells exhibit sexual dimorphism in their response to hyperoxia. Am J Physiol Heart Circ Physiol. 2018 11 01; 315(5):H1287-H1292. PMID: 30095998; PMCID: PMC6415740.
      Citations: 13     Fields:    Translation:HumansCells
    30. Lingappan K, Arnold JL, Fernandes CJ, Pammi M, Lingappan K, Arnold JL, Fernandes CJ, Pammi M. Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates. Cochrane Database Syst Rev. 2018 06 04; 6:CD009975. PMID: 29862490; PMCID: PMC6513507.
      Citations: 16     Fields:    Translation:Humans
    31. Thomas AN, Hagan JL, Lingappan K, Thomas AN, Hagan JL, Lingappan K. Noninvasive ventilation strategies: which to choose? J Perinatol. 2018 05; 38(5):447-450. PMID: 29282353.
      Citations: 1     Fields:    Translation:Humans
    32. Pammi M, Lingappan K, Carbajal MM, Suresh GK, Pammi M, Lingappan K, Carbajal MM, Suresh GK. Focused Evidence-Based Medicine Curriculum for Trainees in Neonatal-Perinatal Medicine. MedEdPORTAL. 2017 12 26; 13:10664. PMID: 30800864; PMCID: PMC6338140.
      Citations: 3     Fields:    Translation:Humans
    33. Lingappan K, Maturu P, Liang YW, Jiang W, Wang L, Moorthy B, Couroucli XI, Lingappan K, Maturu P, Liang YW, Jiang W, Wang L, Moorthy B, Couroucli XI. ?-Naphthoflavone treatment attenuates neonatal hyperoxic lung injury in wild type and Cyp1a2-knockout mice. Toxicol Appl Pharmacol. 2018 01 15; 339:133-142. PMID: 29180065; PMCID: PMC5758404.
      Citations: 2     Fields:    Translation:Animals
    34. Lingappan K, Lingappan K. NF-?B in Oxidative Stress. Curr Opin Toxicol. 2018 Feb; 7:81-86. PMID: 29862377; PMCID: PMC5978768.
      Citations: 147     
    35. Jiang W, Maturu P, Liang YW, Wang L, Lingappan K, Couroucli X, Jiang W, Maturu P, Liang YW, Wang L, Lingappan K, Couroucli X. Hyperoxia-mediated transcriptional activation of cytochrome P4501A1 (CYP1A1) and decreased susceptibility to oxygen-mediated lung injury in newborn mice. Biochem Biophys Res Commun. 2018 01 01; 495(1):408-413. PMID: 29101037; PMCID: PMC5743196.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    36. Coarfa C, Zhang Y, Maity S, Perera DN, Jiang W, Wang L, Couroucli X, Moorthy B, Lingappan K, Coarfa C, Zhang Y, Maity S, Perera DN, Jiang W, Wang L, Couroucli X, Moorthy B, Lingappan K. Sexual dimorphism of the pulmonary transcriptome in neonatal hyperoxic lung injury: identification of angiogenesis as a key pathway. Am J Physiol Lung Cell Mol Physiol. 2017 Dec 01; 313(6):L991-L1005. PMID: 28818871; PMCID: PMC5814706.
      Citations: 12     Fields:    Translation:AnimalsCells
    37. Zhang Y, Jiang W, Wang L, Lingappan K, Zhang Y, Jiang W, Wang L, Lingappan K. Sex-specific differences in the modulation of Growth Differentiation Factor 15 (GDF15) by hyperoxia in vivo and in vitro: Role of Hif-1a. Toxicol Appl Pharmacol. 2017 10 01; 332:8-14. PMID: 28734801; PMCID: PMC5592142.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    38. Parmekar S, Arnold JL, Anselmo C, Pammi M, Hagan J, Fernandes CJ, Lingappan K, Parmekar S, Arnold JL, Anselmo C, Pammi M, Hagan J, Fernandes CJ, Lingappan K. Mind the gap: can videolaryngoscopy bridge the competency gap in neonatal endotracheal intubation among pediatric trainees? a randomized controlled study. J Perinatol. 2017 08; 37(8):979-983. PMID: 28518132.
      Citations: 5     Fields:    Translation:Humans
    39. Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI, Maturu P, Wei-Liang Y, Jiang W, Wang L, Lingappan K, Barrios R, Liang Y, Moorthy B, Couroucli XI. Newborn Mice Lacking the Gene for Cyp1a1 Are More Susceptible to Oxygen-Mediated Lung Injury, and Are Rescued by Postnatal ?-Naphthoflavone Administration: Implications for Bronchopulmonary Dysplasia in Premature Infants. Toxicol Sci. 2017 05 01; 157(1):260-271. PMID: 28201809; PMCID: PMC5837454.
      Citations: 13     Fields:    Translation:HumansAnimals
    40. Lingappan K, Maity S, Jiang W, Wang L, Couroucli X, Veith A, Zhou G, Coarfa C, Moorthy B, Lingappan K, Maity S, Jiang W, Wang L, Couroucli X, Veith A, Zhou G, Coarfa C, Moorthy B. Role of Cytochrome P450 (CYP)1A in Hyperoxic Lung Injury: Analysis of the Transcriptome and Proteome. Sci Rep. 2017 04 04; 7(1):642. PMID: 28377578; PMCID: PMC5428698.
      Citations: 10     Fields:    Translation:AnimalsCells
    41. Zhang Y, Lingappan K, Zhang Y, Lingappan K. Differential sex-specific effects of oxygen toxicity in human umbilical vein endothelial cells. Biochem Biophys Res Commun. 2017 04 29; 486(2):431-437. PMID: 28315681; PMCID: PMC5423444.
      Citations: 11     Fields:    Translation:HumansCells
    42. Hoover J, Lingappan K, Hoover J, Lingappan K. One-Month-Old Infant With Hypotonia and Cardiorespiratory Arrest. Clin Pediatr (Phila). 2017 04; 56(4):397-398. PMID: 27356634.
      Citations:    Fields:    Translation:Humans
    43. Lingappan K, Jiang W, Wang L, Moorthy B, Lingappan K, Jiang W, Wang L, Moorthy B. Sex-specific differences in neonatal hyperoxic lung injury. Am J Physiol Lung Cell Mol Physiol. 2016 Aug 01; 311(2):L481-93. PMID: 27343189; PMCID: PMC5504425.
      Citations: 39     Fields:    Translation:Animals
    44. Dinu D, Chu C, Veith A, Lingappan K, Couroucli X, Jefcoate CR, Sheibani N, Moorthy B, Dinu D, Chu C, Veith A, Lingappan K, Couroucli X, Jefcoate CR, Sheibani N, Moorthy B. Mechanistic role of cytochrome P450 (CYP)1B1 in oxygen-mediated toxicity in pulmonary cells: A novel target for prevention of hyperoxic lung injury. Biochem Biophys Res Commun. 2016 08 05; 476(4):346-351. PMID: 27235555; PMCID: PMC4935552.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    45. Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ, Lingappan K, Kaiser JR, Srinivasan C, Gunn AJ. Relationship between PCO2 and unfavorable outcome in infants with moderate-to-severe hypoxic ischemic encephalopathy. Pediatr Res. 2016 08; 80(2):204-8. PMID: 27049290.
      Citations: 14     Fields:    Translation:Humans
    46. Lingappan K, Moorthy B, Lingappan K, Moorthy B. Can maternal DHA supplementation offer long-term protection against neonatal hyperoxic lung injury? Am J Physiol Lung Cell Mol Physiol. 2015 Dec 15; 309(12):L1383-6. PMID: 26361877; PMCID: PMC4683313.
      Citations:    Fields:    Translation:HumansAnimals
    47. Tiwari KK, Moorthy B, Lingappan K, Tiwari KK, Moorthy B, Lingappan K. Role of GDF15 (growth and differentiation factor 15) in pulmonary oxygen toxicity. Toxicol In Vitro. 2015 Oct; 29(7):1369-76. PMID: 26004619; PMCID: PMC4553106.
      Citations: 19     Fields:    Translation:HumansCells
    48. Lingappan K, Jiang W, Wang L, Couroucli XI, Moorthy B, Lingappan K, Jiang W, Wang L, Couroucli XI, Moorthy B. Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A. Toxicology. 2015 May 04; 331:14-23. PMID: 25703676; PMCID: PMC4406849.
      Citations: 18     Fields:    Translation:Animals
    49. Lingappan K, Arnold JL, Shaw TL, Fernandes CJ, Pammi M, Lingappan K, Arnold JL, Shaw TL, Fernandes CJ, Pammi M. Videolaryngoscopy versus direct laryngoscopy for tracheal intubation in neonates. Cochrane Database Syst Rev. 2015 Feb 18; (2):CD009975. PMID: 25691129.
      Citations: 8     Fields:    Translation:Humans
    50. Wang L, Lingappan K, Jiang W, Couroucli XI, Welty SE, Shivanna B, Barrios R, Wang G, Firoze Khan M, Gonzalez FJ, Jackson Roberts L, Moorthy B, Wang L, Lingappan K, Jiang W, Couroucli XI, Welty SE, Shivanna B, Barrios R, Wang G, Firoze Khan M, Gonzalez FJ, Jackson Roberts L, Moorthy B. Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury. Free Radic Biol Med. 2015 May; 82:147-59. PMID: 25680282; PMCID: PMC4418801.
      Citations: 18     Fields:    Translation:AnimalsCells
    51. Lingappan K, Srinivasan C, Jiang W, Wang L, Couroucli XI, Moorthy B, Lingappan K, Srinivasan C, Jiang W, Wang L, Couroucli XI, Moorthy B. Analysis of the transcriptome in hyperoxic lung injury and sex-specific alterations in gene expression. PLoS One. 2014; 9(7):e101581. PMID: 25003466; PMCID: PMC4086819.
      Citations: 18     Fields:    Translation:AnimalsCells
    52. Tiwari KK, Chu C, Couroucli X, Moorthy B, Lingappan K, Tiwari KK, Chu C, Couroucli X, Moorthy B, Lingappan K. Differential concentration-specific effects of caffeine on cell viability, oxidative stress, and cell cycle in pulmonary oxygen toxicity in vitro. Biochem Biophys Res Commun. 2014 Aug 08; 450(4):1345-50. PMID: 24997337; PMCID: PMC4216694.
      Citations: 14     Fields:    Translation:AnimalsCells
    53. Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B, Lingappan K, Jiang W, Wang L, Wang G, Couroucli XI, Shivanna B, Welty SE, Barrios R, Khan MF, Nebert DW, Roberts LJ, Moorthy B. Mice deficient in the gene for cytochrome P450 (CYP)1A1 are more susceptible than wild-type to hyperoxic lung injury: evidence for protective role of CYP1A1 against oxidative stress. Toxicol Sci. 2014 Sep; 141(1):68-77. PMID: 24893714; PMCID: PMC4200035.
      Citations: 25     Fields:    Translation:AnimalsCells
    54. Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI, Thakur VS, Liang YW, Lingappan K, Jiang W, Wang L, Barrios R, Zhou G, Guntupalli B, Shivanna B, Maturu P, Welty SE, Moorthy B, Couroucli XI. Increased susceptibility to hyperoxic lung injury and alveolar simplification in newborn rats by prenatal administration of benzo[a]pyrene. Toxicol Lett. 2014 Oct 15; 230(2):322-32. PMID: 24657529; PMCID: PMC4169345.
      Citations: 14     Fields:    Translation:Animals
    55. Lingappan K, Arunachalam A, Pammi M, Lingappan K, Arunachalam A, Pammi M. Lactoferrin and the newborn: current perspectives. Expert Rev Anti Infect Ther. 2013 Jul; 11(7):695-707. PMID: 23879609.
      Citations: 7     Fields:    Translation:HumansAnimals
    56. Lingappan K, Jiang W, Wang L, Couroucli XI, Barrios R, Moorthy B, Lingappan K, Jiang W, Wang L, Couroucli XI, Barrios R, Moorthy B. Sex-specific differences in hyperoxic lung injury in mice: implications for acute and chronic lung disease in humans. Toxicol Appl Pharmacol. 2013 Oct 15; 272(2):281-90. PMID: 23792423; PMCID: PMC4201582.
      Citations: 26     Fields:    Translation:HumansAnimals
    57. Singh M, Lingappan K, Singh M, Lingappan K. Whooping cough: the current scene. Chest. 2006 Nov; 130(5):1547-53. PMID: 17099036.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic Health
    LINGAPPAN's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (236)
    Explore
    _
    Co-Authors (38)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _