Last Name


TitleClinical Instructor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address4003 WOODLAWN
vCardDownload vCard

    Collapse Additional Tools and Researcher Information 
    Collapse Verify Publications

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    List All   |   Timeline
    1. Soonthornvacharin S, Rodriguez-Frandsen A, Zhou Y, Galvez F, Huffmaster NJ, Tripathi S, Balasubramaniam VR, Inoue A, de Castro E, Moulton H, Stein DA, Sánchez-Aparicio MT, De Jesus PD, Nguyen Q, König R, Krogan NJ, García-Sastre A, Yoh SM, Chanda SK. Systems-based analysis of RIG-I-dependent signalling identifies KHSRP as an inhibitor of RIG-I receptor activation. Nat Microbiol. 2017 Mar 01; 2:17022. PMID: 28248290.
      View in: PubMed
    2. Lang AE, Rodriguez RL, Boyd JT, Chouinard S, Zadikoff C, Espay AJ, Slevin JT, Fernandez HH, Lew MF, Stein DA, Odin P, Fung VS, Klostermann F, Fasano A, Draganov PV, Schmulewitz N, Robieson WZ, Eaton S, Chatamra K, Benesh JA, Dubow J. Integrated safety of levodopa-carbidopa intestinal gel from prospective clinical trials. Mov Disord. 2016 Apr; 31(4):538-46. PMID: 26695437.
      View in: PubMed
    3. Tripathi S, Pohl MO, Zhou Y, Rodriguez-Frandsen A, Wang G, Stein DA, Moulton HM, DeJesus P, Che J, Mulder LC, Yángüez E, Andenmatten D, Pache L, Manicassamy B, Albrecht RA, Gonzalez MG, Nguyen Q, Brass A, Elledge S, White M, Shapira S, Hacohen N, Karlas A, Meyer TF, Shales M, Gatorano A, Johnson JR, Jang G, Johnson T, Verschueren E, Sanders D, Krogan N, Shaw M, König R, Stertz S, García-Sastre A, Chanda SK. Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. Cell Host Microbe. 2015 Dec 9; 18(6):723-35. PMID: 26651948.
      View in: PubMed
    4. Nan Y, Ma Z, Kannan H, Stein DA, Iversen PI, Meng XJ, Zhang YJ. Inhibition of hepatitis E virus replication by peptide-conjugated morpholino oligomers. Antiviral Res. 2015 Aug; 120:134-9. PMID: 26086884.
      View in: PubMed
    5. Rajsbaum R, Versteeg GA, Schmid S, Maestre AM, Belicha-Villanueva A, Martínez-Romero C, Patel JR, Morrison J, Pisanelli G, Miorin L, Laurent-Rolle M, Moulton HM, Stein DA, Fernandez-Sesma A, tenOever BR, García-Sastre A. Unanchored K48-linked polyubiquitin synthesized by the E3-ubiquitin ligase TRIM6 stimulates the interferon-IKK? kinase-mediated antiviral response. Immunity. 2014 Jun 19; 40(6):880-95. PMID: 24882218; PMCID: PMC4114019.
    6. Smith JL, Stein DA, Shum D, Fischer MA, Radu C, Bhinder B, Djaballah H, Nelson JA, Früh K, Hirsch AJ. Inhibition of dengue virus replication by a class of small-molecule compounds that antagonize dopamine receptor d4 and downstream mitogen-activated protein kinase signaling. J Virol. 2014 May; 88(10):5533-42. PMID: 24599995; PMCID: PMC4019099.
    7. Fischer MA, Smith JL, Shum D, Stein DA, Parkins C, Bhinder B, Radu C, Hirsch AJ, Djaballah H, Nelson JA, Früh K. Flaviviruses are sensitive to inhibition of thymidine synthesis pathways. J Virol. 2013 Sep; 87(17):9411-9. PMID: 23824813; PMCID: PMC3754125.
    8. Neuman BW, Bederka LH, Stein DA, Ting JP, Moulton HM, Buchmeier MJ. Development of peptide-conjugated morpholino oligomers as pan-arenavirus inhibitors. Antimicrob Agents Chemother. 2011 Oct; 55(10):4631-8. PMID: 21825302; PMCID: PMC3186971.
    9. Stein DA, Perry ST, Buck MD, Oehmen CS, Fischer MA, Poore E, Smith JL, Lancaster AM, Hirsch AJ, Slifka MK, Nelson JA, Shresta S, Früh K. Inhibition of dengue virus infections in cell cultures and in AG129 mice by a small interfering RNA targeting a highly conserved sequence. J Virol. 2011 Oct; 85(19):10154-66. PMID: 21795337; PMCID: PMC3196423.
    10. Opriessnig T, Patel D, Wang R, Halbur PG, Meng XJ, Stein DA, Zhang YJ. Inhibition of porcine reproductive and respiratory syndrome virus infection in piglets by a peptide-conjugated morpholino oligomer. Antiviral Res. 2011 Jul; 91(1):36-42. PMID: 21554902.
      View in: PubMed
    11. Böttcher-Friebertshäuser E, Stein DA, Klenk HD, Garten W. Inhibition of influenza virus infection in human airway cell cultures by an antisense peptide-conjugated morpholino oligomer targeting the hemagglutinin-activating protease TMPRSS2. J Virol. 2011 Feb; 85(4):1554-62. PMID: 21123387; PMCID: PMC3028871.
    12. Shum D, Smith JL, Hirsch AJ, Bhinder B, Radu C, Stein DA, Nelson JA, Früh K, Djaballah H. High-content assay to identify inhibitors of dengue virus infection. Assay Drug Dev Technol. 2010 Oct; 8(5):553-70. PMID: 20973722; PMCID: PMC2962577.
    13. Zhang HM, Ye X, Su Y, Yuan J, Liu Z, Stein DA, Yang D. Coxsackievirus B3 infection activates the unfolded protein response and induces apoptosis through downregulation of p58IPK and activation of CHOP and SREBP1. J Virol. 2010 Sep; 84(17):8446-59. PMID: 20554776; PMCID: PMC2918999.
    14. Anantpadma M, Stein DA, Vrati S. Inhibition of Japanese encephalitis virus replication in cultured cells and mice by a peptide-conjugated morpholino oligomer. J Antimicrob Chemother. 2010 May; 65(5):953-61. PMID: 20299495.
      View in: PubMed
    15. Zhang J, Stein DA, Timoney PJ, Balasuriya UB. Curing of HeLa cells persistently infected with equine arteritis virus by a peptide-conjugated morpholino oligomer. Virus Res. 2010 Jun; 150(1-2):138-42. PMID: 20206215.
      View in: PubMed
    16. Eide K, Moerdyk-Schauwecker M, Stein DA, Bildfell R, Koelle DM, Jin L. Reduction of herpes simplex virus type-2 replication in cell cultures and in rodent models with peptide-conjugated morpholino oligomers. Antivir Ther. 2010; 15(8):1141-9. PMID: 21149921.
      View in: PubMed
    17. Moerdyk-Schauwecker M, Stein DA, Eide K, Blouch RE, Bildfell R, Iversen P, Jin L. Inhibition of HSV-1 ocular infection with morpholino oligomers targeting ICP0 and ICP27. Antiviral Res. 2009 Nov; 84(2):131-41. PMID: 19665486.
      View in: PubMed
    18. Sleeman K, Stein DA, Tamin A, Reddish M, Iversen PL, Rota PA. Inhibition of measles virus infections in cell cultures by peptide-conjugated morpholino oligomers. Virus Res. 2009 Mar; 140(1-2):49-56. PMID: 19059443.
      View in: PubMed
    19. Patel D, Stein DA, Zhang YJ. Morpholino oligomer-mediated protection of porcine pulmonary alveolar macrophages from arterivirus-induced cell death. Antivir Ther. 2009; 14(7):899-909. PMID: 19918094.
      View in: PubMed
    20. Krähling V, Stein DA, Spiegel M, Weber F, Mühlberger E. Severe acute respiratory syndrome coronavirus triggers apoptosis via protein kinase R but is resistant to its antiviral activity. J Virol. 2009 Mar; 83(5):2298-309. PMID: 19109397; PMCID: PMC2643707.
    21. Zhang B, Dong H, Stein DA, Shi PY. Co-selection of West Nile virus nucleotides that confer resistance to an antisense oligomer while maintaining long-distance RNA/RNA base pairings. Virology. 2008 Dec 5; 382(1):98-106. PMID: 18842280; PMCID: PMC3202013.
    22. Stein DA, Huang CY, Silengo S, Amantana A, Crumley S, Blouch RE, Iversen PL, Kinney RM. Treatment of AG129 mice with antisense morpholino oligomers increases survival time following challenge with dengue 2 virus. J Antimicrob Chemother. 2008 Sep; 62(3):555-65. PMID: 18567576.
      View in: PubMed
    23. Paessler S, Rijnbrand R, Stein DA, Ni H, Yun NE, Dziuba N, Borisevich V, Seregin A, Ma Y, Blouch R, Iversen PL, Zacks MA. Inhibition of alphavirus infection in cell culture and in mice with antisense morpholino oligomers. Virology. 2008 Jul 5; 376(2):357-70. PMID: 18468653; PMCID: PMC2447162.
    24. Lai SH, Stein DA, Guerrero-Plata A, Liao SL, Ivanciuc T, Hong C, Iversen PL, Casola A, Garofalo RP. Inhibition of respiratory syncytial virus infections with morpholino oligomers in cell cultures and in mice. Mol Ther. 2008 Jun; 16(6):1120-8. PMID: 18443602; PMCID: PMC2782410.
    25. Gabriel G, Nordmann A, Stein DA, Iversen PL, Klenk HD. Morpholino oligomers targeting the PB1 and NP genes enhance the survival of mice infected with highly pathogenic influenza A H7N7 virus. J Gen Virol. 2008 Apr; 89(Pt 4):939-48. PMID: 18343835.
      View in: PubMed
    26. Lupfer C, Stein DA, Mourich DV, Tepper SE, Iversen PL, Pastey M. Inhibition of influenza A H3N8 virus infections in mice by morpholino oligomers. Arch Virol. 2008; 153(5):929-37. PMID: 18369525.
      View in: PubMed
    27. Stone JK, Rijnbrand R, Stein DA, Ma Y, Yang Y, Iversen PL, Andino R. A morpholino oligomer targeting highly conserved internal ribosome entry site sequence is able to inhibit multiple species of picornavirus. Antimicrob Agents Chemother. 2008 Jun; 52(6):1970-81. PMID: 18347107; PMCID: PMC2415775.
    28. Zhang YJ, Bonaparte RS, Patel D, Stein DA, Iversen PL. Blockade of viral interleukin-6 expression of Kaposi's sarcoma-associated herpesvirus. Mol Cancer Ther. 2008 Mar; 7(3):712-20. PMID: 18347156; PMCID: PMC2377409.
    29. Zhang B, Dong H, Stein DA, Iversen PL, Shi PY. West Nile virus genome cyclization and RNA replication require two pairs of long-distance RNA interactions. Virology. 2008 Mar 30; 373(1):1-13. PMID: 18258275.
      View in: PubMed
    30. Stein DA. Inhibition of RNA virus infections with peptide-conjugated morpholino oligomers. Curr Pharm Des. 2008; 14(25):2619-34. PMID: 18991679.
      View in: PubMed
    31. Stein DA, Shi PY. Nucleic acid-based inhibition of flavivirus infections. Front Biosci. 2008; 13:1385-95. PMID: 17981637.
      View in: PubMed
    32. Lebleu B, Moulton HM, Abes R, Ivanova GD, Abes S, Stein DA, Iversen PL, Arzumanov AA, Gait MJ. Cell penetrating peptide conjugates of steric block oligonucleotides. Adv Drug Deliv Rev. 2008 Mar 1; 60(4-5):517-29. PMID: 18037527.
      View in: PubMed
    33. Patel D, Opriessnig T, Stein DA, Halbur PG, Meng XJ, Iversen PL, Zhang YJ. Peptide-conjugated morpholino oligomers inhibit porcine reproductive and respiratory syndrome virus replication. Antiviral Res. 2008 Feb; 77(2):95-107. PMID: 17959259.
      View in: PubMed
    34. Vagnozzi A, Stein DA, Iversen PL, Rieder E. Inhibition of foot-and-mouth disease virus infections in cell cultures with antisense morpholino oligomers. J Virol. 2007 Nov; 81(21):11669-80. PMID: 17728223; PMCID: PMC2168802.
    35. Moulton HM, Fletcher S, Neuman BW, McClorey G, Stein DA, Abes S, Wilton SD, Buchmeier MJ, Lebleu B, Iversen PL. Cell-penetrating peptide-morpholino conjugates alter pre-mRNA splicing of DMD (Duchenne muscular dystrophy) and inhibit murine coronavirus replication in vivo. Biochem Soc Trans. 2007 Aug; 35(Pt 4):826-8. PMID: 17635157.
      View in: PubMed
    36. Deas TS, Bennett CJ, Jones SA, Tilgner M, Ren P, Behr MJ, Stein DA, Iversen PL, Kramer LD, Bernard KA, Shi PY. In vitro resistance selection and in vivo efficacy of morpholino oligomers against West Nile virus. Antimicrob Agents Chemother. 2007 Jul; 51(7):2470-82. PMID: 17485503; PMCID: PMC1913242.
    37. Burrer R, Neuman BW, Ting JP, Stein DA, Moulton HM, Iversen PL, Kuhn P, Buchmeier MJ. Antiviral effects of antisense morpholino oligomers in murine coronavirus infection models. J Virol. 2007 Jun; 81(11):5637-48. PMID: 17344287; PMCID: PMC1900280.
    38. Yuan J, Stein DA, Lim T, Qiu D, Coughlin S, Liu Z, Wang Y, Blouch R, Moulton HM, Iversen PL, Yang D. Inhibition of coxsackievirus B3 in cell cultures and in mice by peptide-conjugated morpholino oligomers targeting the internal ribosome entry site. J Virol. 2006 Dec; 80(23):11510-9. PMID: 16987987; PMCID: PMC1642606.
    39. Ge Q, Pastey M, Kobasa D, Puthavathana P, Lupfer C, Bestwick RK, Iversen PL, Chen J, Stein DA. Inhibition of multiple subtypes of influenza A virus in cell cultures with morpholino oligomers. Antimicrob Agents Chemother. 2006 Nov; 50(11):3724-33. PMID: 16966399; PMCID: PMC1635187.
    40. Zhang YJ, Stein DA, Fan SM, Wang KY, Kroeker AD, Meng XJ, Iversen PL, Matson DO. Suppression of porcine reproductive and respiratory syndrome virus replication by morpholino antisense oligomers. Vet Microbiol. 2006 Oct 31; 117(2-4):117-29. PMID: 16839712.
      View in: PubMed
    41. Zhang YJ, Wang KY, Stein DA, Patel D, Watkins R, Moulton HM, Iversen PL, Matson DO. Inhibition of replication and transcription activator and latency-associated nuclear antigen of Kaposi's sarcoma-associated herpesvirus by morpholino oligomers. Antiviral Res. 2007 Jan; 73(1):12-23. PMID: 16842866; PMCID: PMC2390898.
    42. Smith AW, Iversen PL, Skilling DE, Stein DA, Bok K, Matson DO. Vesivirus viremia and seroprevalence in humans. J Med Virol. 2006 May; 78(5):693-701. PMID: 16555277.
      View in: PubMed
    43. Enterlein S, Warfield KL, Swenson DL, Stein DA, Smith JL, Gamble CS, Kroeker AD, Iversen PL, Bavari S, Mühlberger E. VP35 knockdown inhibits Ebola virus amplification and protects against lethal infection in mice. Antimicrob Agents Chemother. 2006 Mar; 50(3):984-93. PMID: 16495261; PMCID: PMC1426423.
    44. Warfield KL, Swenson DL, Olinger GG, Nichols DK, Pratt WD, Blouch R, Stein DA, Aman MJ, Iversen PL, Bavari S. Gene-specific countermeasures against Ebola virus based on antisense phosphorodiamidate morpholino oligomers. PLoS Pathog. 2006 Jan; 2(1):e1. PMID: 16415982; PMCID: PMC1326218.
    45. Neuman BW, Stein DA, Kroeker AD, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition and escape of SARS-CoV treated with antisense morpholino oligomers. Adv Exp Med Biol. 2006; 581:567-71. PMID: 17037599.
      View in: PubMed
    46. van den Born E, Stein DA, Iversen PL, Snijder EJ. Antiviral activity of morpholino oligomers designed to block various aspects of Equine arteritis virus amplification in cell culture. J Gen Virol. 2005 Nov; 86(Pt 11):3081-90. PMID: 16227231.
      View in: PubMed
    47. Holden KL, Stein DA, Pierson TC, Ahmed AA, Clyde K, Iversen PL, Harris E. Inhibition of dengue virus translation and RNA synthesis by a morpholino oligomer targeted to the top of the terminal 3' stem-loop structure. Virology. 2006 Jan 20; 344(2):439-52. PMID: 16214197.
      View in: PubMed
    48. Neuman BW, Stein DA, Kroeker AD, Churchill MJ, Kim AM, Kuhn P, Dawson P, Moulton HM, Bestwick RK, Iversen PL, Buchmeier MJ. Inhibition, escape, and attenuated growth of severe acute respiratory syndrome coronavirus treated with antisense morpholino oligomers. J Virol. 2005 Aug; 79(15):9665-76. PMID: 16014928; PMCID: PMC1181598.
    49. Alonso M, Stein DA, Thomann E, Moulton HM, Leong JC, Iversen P, Mourich DV. Inhibition of infectious haematopoietic necrosis virus in cell cultures with peptide-conjugated morpholino oligomers. J Fish Dis. 2005 Jul; 28(7):399-410. PMID: 16083445.
      View in: PubMed
    50. Nelson MH, Stein DA, Kroeker AD, Hatlevig SA, Iversen PL, Moulton HM. Arginine-rich peptide conjugation to morpholino oligomers: effects on antisense activity and specificity. Bioconjug Chem. 2005 Jul-Aug; 16(4):959-66. PMID: 16029037.
      View in: PubMed
    51. Kinney RM, Huang CY, Rose BC, Kroeker AD, Dreher TW, Iversen PL, Stein DA. Inhibition of dengue virus serotypes 1 to 4 in vero cell cultures with morpholino oligomers. J Virol. 2005 Apr; 79(8):5116-28. PMID: 15795296; PMCID: PMC1069583.
    52. Deas TS, Binduga-Gajewska I, Tilgner M, Ren P, Stein DA, Moulton HM, Iversen PL, Kauffman EB, Kramer LD, Shi PY. Inhibition of flavivirus infections by antisense oligomers specifically suppressing viral translation and RNA replication. J Virol. 2005 Apr; 79(8):4599-609. PMID: 15795246; PMCID: PMC1069577.
    53. Neuman BW, Stein DA, Kroeker AD, Paulino AD, Moulton HM, Iversen PL, Buchmeier MJ. Antisense morpholino-oligomers directed against the 5' end of the genome inhibit coronavirus proliferation and growth. J Virol. 2004 Jun; 78(11):5891-9. PMID: 15140987; PMCID: PMC415795.
    54. London CA, Sekhon HS, Arora V, Stein DA, Iversen PL, Devi GR. A novel antisense inhibitor of MMP-9 attenuates angiogenesis, human prostate cancer cell invasion and tumorigenicity. Cancer Gene Ther. 2003 Nov; 10(11):823-32. PMID: 14605668.
      View in: PubMed
    55. Geller BL, Deere JD, Stein DA, Kroeker AD, Moulton HM, Iversen PL. Inhibition of gene expression in Escherichia coli by antisense phosphorodiamidate morpholino oligomers. Antimicrob Agents Chemother. 2003 Oct; 47(10):3233-9. PMID: 14506035; PMCID: PMC201127.
    56. Smith AW, Matson DO, Stein DA, Skilling DE, Kroeker AD, Berke T, Iversen PL. Antisense treatment of caliciviridae: an emerging disease agent of animals and humans. Curr Opin Mol Ther. 2002 Apr; 4(2):177-84. PMID: 12044040.
      View in: PubMed
    57. Smith AW, Skilling DE, Matson DO, Kroeker AD, Stein DA, Berke T, Iversen PL. Detection of vesicular exanthema of swine-like calicivirus in tissues from a naturally infected spontaneously aborted bovine fetus. J Am Vet Med Assoc. 2002 Feb 15; 220(4):455-8. PMID: 11860239.
      View in: PubMed
    58. Stein DA, Skilling DE, Iversen PL, Smith AW. Inhibition of Vesivirus infections in mammalian tissue culture with antisense morpholino oligomers. Antisense Nucleic Acid Drug Dev. 2001 Oct; 11(5):317-25. PMID: 11763348.
      View in: PubMed
    59. Arora V, Knapp DC, Smith BL, Statdfield ML, Stein DA, Reddy MT, Weller DD, Iversen PL. c-Myc antisense limits rat liver regeneration and indicates role for c-Myc in regulating cytochrome P-450 3A activity. J Pharmacol Exp Ther. 2000 Mar; 292(3):921-8. PMID: 10688605.
      View in: PubMed
    STEIN's Networks
    Click the "See All" links for more information and interactive visualizations!
    Concepts Expand Description
    Co-Authors Expand Description
    Similar People Expand Description
    Same Department Expand Description