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JAMES WILLERSON

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Cardiology
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    P50HL017669     (SAMBROOK, JOSEPH)Jan 1, 1975 - Dec 31, 1994
    NIH/NHLBI
    SCOR IN CORONARY AND VASCULAR DISEASES
    Role: Co-Principal Investigator

    N01HV072942     (WILLERSON, JAMES T)Sep 15, 1977 - Jul 14, 1986
    NIH/NHLBI
    THERAPY TO PROTECT ISCHEMIC MYOCARDIUM/CLINICAL TESTS
    Role: Principal Investigator

    T32HL007591     (TAEGTMEYER, HEINRICH)Jul 1, 1985 - Jun 30, 2005
    NIH/NHLBI
    MOLECULAR AND CELLULAR MECHANISMS OF HEART DISEASE
    Role: Co-Principal Investigator

    R01HL050179     (WILLERSON, JAMES T.)Jun 1, 1993 - May 31, 1998
    NIH/NHLBI
    CORONARY ARTERY RESTENOSIS--A MAJOR CARDIOLOGY PROBLEM
    Role: Principal Investigator

    R01HL054839     (WILLERSON, JAMES T.)Aug 1, 1996 - Apr 30, 2001
    NIH/NHLBI
    PREVENTION OF THROMBOSIS IN ANGIOPLASTY INJURED ARTERIES
    Role: Principal Investigator

    U01HL087365     (WILLERSON, JAMES T.)Jan 1, 2007 - Feb 29, 2012
    NIH/NHLBI
    Cardiovascular Cell Therapy Research Network
    Role: Principal Investigator

    UM1HL087365     (WILLERSON, JAMES T.)Jan 1, 2007 - Feb 28, 2019
    NIH/NHLBI
    Cardiovascular Cell Therapy Research Network
    Role: Principal Investigator

    P30HL101336     (WILLERSON, JAMES T.)Sep 30, 2009 - Aug 31, 2012
    NIH/NHLBI
    New Cardiovascular Research Scientist for Molecular and Cellular Biology Core
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Hernández-Rivera M, Cho SY, Moghaddam SE, Cheong BY, Cabreira-Hansen MDG, Willerson JT, Perin EC, Wilson LJ. Labeling Stem Cells with a New Hybrid Bismuth/Carbon Nanotube Contrast Agent for X-Ray Imaging. Contrast Media Mol Imaging. 2019; 2019:2183051. PMID: 31281232.
      View in: PubMed
    2. Willerson JT. The Medical and Device-Related Treatment of Heart Failure. Circ Res. 2019 05 24; 124(11):1519. PMID: 31120816.
      View in: PubMed
    3. Cheedipudi SM, Matkovich SJ, Coarfa C, Hu X, Robertson MJ, Sweet M, Taylor M, Mestroni L, Cleveland J, Willerson JT, Gurha P, Marian AJ. Genomic Reorganization of Lamin-Associated Domains in Cardiac Myocytes Is Associated With Differential Gene Expression and DNA Methylation in Human Dilated Cardiomyopathy. Circ Res. 2019 04 12; 124(8):1198-1213. PMID: 30739589.
      View in: PubMed
    4. Taylor DA, Willerson JT. Racial Disparities in CD34+ Cells and Their Influence on Cardiovascular Repair. Circ Res. 2018 08 03; 123(4):401-403. PMID: 30355257.
      View in: PubMed
    5. Angelini P, Cheong BY, Lenge De Rosen VV, Lopez A, Uribe C, Masso AH, Ali SW, Davis BR, Muthupillai R, Willerson JT. High-Risk Cardiovascular Conditions in Sports-Related Sudden Death: Prevalence in 5,169 Schoolchildren Screened via Cardiac Magnetic Resonance. Tex Heart Inst J. 2018 08; 45(4):205-213. PMID: 30374227.
      View in: PubMed
    6. Moghaddam SE, Hernández-Rivera M, Zaibaq NG, Ajala A, da Graça Cabreira-Hansen M, Mowlazadeh-Haghighi S, Willerson JT, Perin EC, Muthupillai R, Wilson LJ. A New High-Performance Gadonanotube-Polymer Hybrid Material for Stem Cell Labeling and Tracking by MRI. Contrast Media Mol Imaging. 2018; 2018:2853736. PMID: 30116161.
      View in: PubMed
    7. Bolli R, Hare JM, March KL, Pepine CJ, Willerson JT, Perin EC, Yang PC, Henry TD, Traverse JH, Mitrani RD, Khan A, Hernandez-Schulman I, Taylor DA, DiFede DL, Lima JAC, Chugh A, Loughran J, Vojvodic RW, Sayre SL, Bettencourt J, Cohen M, Moyé L, Ebert RF, Simari RD. Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit+ Cardiac Stem Cells As Regenerative Therapy for Heart Failure). Circ Res. 2018 06 08; 122(12):1703-1715. PMID: 29703749.
      View in: PubMed
    8. Bolli R, Hare JM, Henry TD, Lenneman CG, March KL, Miller K, Pepine CJ, Perin EC, Traverse JH, Willerson JT, Yang PC, Gee AP, Lima JA, Moyé L, Vojvodic RW, Sayre SL, Bettencourt J, Cohen M, Ebert RF, Simari RD. Rationale and Design of the SENECA (StEm cell iNjECtion in cAncer survivors) Trial. Am Heart J. 2018 07; 201:54-62. PMID: 29910056.
      View in: PubMed
    9. Marian AJ, Tan Y, Li L, Chang J, Syrris P, Hessabi M, Rahbar MH, Willerson JT, Cheong BY, Liu CY, Kleiman NS, Bluemke DA, Nagueh SF. Hypertrophy Regression With N-Acetylcysteine in Hypertrophic Cardiomyopathy (HALT-HCM): A Randomized, Placebo-Controlled, Double-Blind Pilot Study. Circ Res. 2018 04 13; 122(8):1109-1118. PMID: 29540445.
      View in: PubMed
    10. Woodside DG, Tanifum EA, Ghaghada KB, Biediger RJ, Caivano AR, Starosolski ZA, Khounlo S, Bhayana S, Abbasi S, Craft JW, Maxwell DS, Patel C, Stupin IV, Bakthavatsalam D, Market RV, Willerson JT, Dixon RAF, Vanderslice P, Annapragada AV. Magnetic Resonance Imaging of Atherosclerotic Plaque at Clinically Relevant Field Strengths (1T) by Targeting the Integrin a4ß1. Sci Rep. 2018 02 27; 8(1):3733. PMID: 29487319.
      View in: PubMed
    11. Angelini P, Cheong BY, Lenge De Rosen VV, Lopez JA, Uribe C, Masso AH, Ali SW, Davis BR, Muthupillai R, Willerson JT. Magnetic Resonance Imaging-Based Screening Study in a General Population of Adolescents. J Am Coll Cardiol. 2018 02 06; 71(5):579-580. PMID: 29406865.
      View in: PubMed
    12. Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Pinto FJ, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC. Global Overview of the Transnational Alliance for Regenerative Therapies in Cardiovascular Syndromes (TACTICS) Recommendations: A Comprehensive Series of Challenges and Priorities of Cardiovascular Regenerative Medicine. Circ Res. 2018 01 19; 122(2):199-201. PMID: 29348246.
      View in: PubMed
    13. Auguste G, Gurha P, Lombardi R, Coarfa C, Willerson JT, Marian AJ. Suppression of Activated FOXO Transcription Factors in the Heart Prolongs Survival in a Mouse Model of Laminopathies. Circ Res. 2018 03 02; 122(5):678-692. PMID: 29317431.
      View in: PubMed
    14. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Chugh A, Yang PC, Zhao DXM, Ellis SG, Forder JR, Perin EC, Penn MS, Hatzopoulos AK, Chambers JC, Baran KW, Raveendran G, Gee AP, Taylor DA, Moyé L, Ebert RF, Simari RD. TIME Trial: Effect of Timing of Stem Cell Delivery Following ST-Elevation Myocardial Infarction on the Recovery of Global and Regional Left Ventricular Function: Final 2-Year Analysis. Circ Res. 2018 02 02; 122(3):479-488. PMID: 29208679.
      View in: PubMed
    15. Haidari M, Zhang W, Willerson JT, Dixon RAF. Correction to: Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-ß-dependent vascular endothelial cadherin tyrosine phosphorylation. Cardiovasc Diabetol. 2017 10 20; 16(1):136. PMID: 29058597.
      View in: PubMed
    16. Karmouch J, Zhou QQ, Miyake CY, Lombardi R, Kretzschmar K, Bannier-Hélaouët M, Clevers H, Wehrens XHT, Willerson JT, Marian AJ. Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes. Circ Res. 2017 Dec 08; 121(12):1346-1359. PMID: 29018034.
      View in: PubMed
    17. Leach JP, Heallen T, Zhang M, Rahmani M, Morikawa Y, Hill MC, Segura A, Willerson JT, Martin JF. Hippo pathway deficiency reverses systolic heart failure after infarction. Nature. 2017 10 12; 550(7675):260-264. PMID: 28976966.
      View in: PubMed
    18. Fernández-Avilés F, Sanz-Ruiz R, Climent AM, Badimon L, Bolli R, Charron D, Fuster V, Janssens S, Kastrup J, Kim HS, Lüscher TF, Martin JF, Menasché P, Simari RD, Stone GW, Terzic A, Willerson JT, Wu JC. Global position paper on cardiovascular regenerative medicine. Eur Heart J. 2017 09 01; 38(33):2532-2546. PMID: 28575280.
      View in: PubMed
    19. Martin JF, Perin EC, Willerson JT. Direct Stimulation of Cardiogenesis: A New Paradigm for Treating Heart Disease. Circ Res. 2017 06 23; 121(1):13-15. PMID: 28642324.
      View in: PubMed
    20. Willerson JT. The Texas Heart Institute: Part 1-An Historical Perspective. Circ Res. 2017 05 12; 120(10):1545-1547. PMID: 28495989.
      View in: PubMed
    21. Willerson JT. The Texas Heart Institute: Part 2-Working Toward the Next Breakthrough in Cardiovascular Medicine. Circ Res. 2017 05 12; 120(10):1548-1550. PMID: 28495990.
      View in: PubMed
    22. Li L, Bainbridge MN, Tan Y, Willerson JT, Marian AJ. A Potential Oligogenic Etiology of Hypertrophic Cardiomyopathy: A Classic Single-Gene Disorder. Circ Res. 2017 Mar 31; 120(7):1084-1090. PMID: 28223422.
      View in: PubMed
    23. Barac YD, Emrich F, Krutzwakd-Josefson E, Schrepfer S, Sampaio LC, Willerson JT, Robbins RC, Ciechanover A, Mohr FW, Aravot D, Taylor DA. The ubiquitin-proteasome system: A potential therapeutic target for heart failure. J Heart Lung Transplant. 2017 Jul; 36(7):708-714. PMID: 28341100.
      View in: PubMed
    24. Willerson JT. CD133+ Stem Cells in the Treatment of Patients With Refractory Angina. Circ Res. 2017 02 17; 120(4):602-603. PMID: 28209787.
      View in: PubMed
    25. Perin EC, Murphy MP, March KL, Bolli R, Loughran J, Yang PC, Leeper NJ, Dalman RL, Alexander J, Henry TD, Traverse JH, Pepine CJ, Anderson RD, Berceli S, Willerson JT, Muthupillai R, Gahremanpour A, Raveendran G, Velasquez O, Hare JM, Hernandez Schulman I, Kasi VS, Hiatt WR, Ambale-Venkatesh B, Lima JA, Taylor DA, Resende M, Gee AP, Durett AG, Bloom J, Richman S, G'Sell P, Williams S, Khan F, Gyang Ross E, Santoso MR, Goldman J, Leach D, Handberg E, Cheong B, Piece N, DiFede D, Bruhn-Ding B, Caldwell E, Bettencourt J, Lai D, Piller L, Simpson L, Cohen M, Sayre SL, Vojvodic RW, Moyé L, Ebert RF, Simari RD, Hirsch AT. Evaluation of Cell Therapy on Exercise Performance and Limb Perfusion in Peripheral Artery Disease: The CCTRN PACE Trial (Patients With Intermittent Claudication Injected With ALDH Bright Cells). Circulation. 2017 Apr 11; 135(15):1417-1428. PMID: 28209728.
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    26. Fred HL, Willerson JT. Fare Thee Well, Dr. Cooley. Tex Heart Inst J. 2017 02; 44(1):3-6. PMID: 28265204.
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    27. Willerson JT. Denton Arthur Cooley, MD. Circ Res. 2017 01 06; 120(1):17-19. PMID: 28057783.
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    28. Contreras A, Orozco AF, Resende M, Schutt RC, Traverse JH, Henry TD, Lai D, Cooke JP, Bolli R, Cohen ML, Moyé L, Pepine CJ, Yang PC, Perin EC, Willerson JT, Taylor DA. Identification of cardiovascular risk factors associated with bone marrow cell subsets in patients with STEMI: a biorepository evaluation from the CCTRN TIME and LateTIME clinical trials. Basic Res Cardiol. 2017 01; 112(1):3. PMID: 27882430.
      View in: PubMed
    29. Henry TD, Pepine CJ, Lambert CR, Traverse JH, Schatz R, Costa M, Povsic TJ, David Anderson R, Willerson JT, Kesten S, Perin EC. The Athena trials: Autologous adipose-derived regenerative cells for refractory chronic myocardial ischemia with left ventricular dysfunction. Catheter Cardiovasc Interv. 2017 Feb 01; 89(2):169-177. PMID: 27148802.
      View in: PubMed
    30. Gurha P, Chen X, Lombardi R, Willerson JT, Marian AJ. Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro. Circ Res. 2016 Sep 02; 119(6):731-50. PMID: 27470638.
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    31. Bhatnagar A, Bolli R, Johnstone BH, Traverse JH, Henry TD, Pepine CJ, Willerson JT, Perin EC, Ellis SG, Zhao DX, Yang PC, Cooke JP, Schutt RC, Trachtenberg BH, Orozco A, Resende M, Ebert RF, Sayre SL, Simari RD, Moyé L, Cogle CR, Taylor DA. Bone marrow cell characteristics associated with patient profile and cardiac performance outcomes in the LateTIME-Cardiovascular Cell Therapy Research Network (CCTRN) trial. Am Heart J. 2016 09; 179:142-50. PMID: 27595689.
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    32. Lombardi R, Chen SN, Ruggiero A, Gurha P, Czernuszewicz GZ, Willerson JT, Marian AJ. Cardiac Fibro-Adipocyte Progenitors Express Desmosome Proteins and Preferentially Differentiate to Adipocytes Upon Deletion of the Desmoplakin Gene. Circ Res. 2016 06 24; 119(1):41-54. PMID: 27121621.
      View in: PubMed
    33. Kumar VA, Liu Q, Wickremasinghe NC, Shi S, Cornwright TT, Deng Y, Azares A, Moore AN, Acevedo-Jake AM, Agudo NR, Pan S, Woodside DG, Vanderslice P, Willerson JT, Dixon RA, Hartgerink JD. Treatment of hind limb ischemia using angiogenic peptide nanofibers. Biomaterials. 2016 08; 98:113-9. PMID: 27182813.
      View in: PubMed
    34. Deng Y, Yang Z, Terry T, Pan S, Woodside DG, Wang J, Ruan K, Willerson JT, Dixon RA, Liu Q. Prostacyclin-producing human mesenchymal cells target H19 lncRNA to augment endogenous progenitor function in hindlimb ischaemia. Nat Commun. 2016 Apr 15; 7:11276. PMID: 27080438.
      View in: PubMed
    35. Madonna R, Van Laake LW, Davidson SM, Engel FB, Hausenloy DJ, Lecour S, Leor J, Perrino C, Schulz R, Ytrehus K, Landmesser U, Mummery CL, Janssens S, Willerson J, Eschenhagen T, Ferdinandy P, Sluijter JP. Position Paper of the European Society of Cardiology Working Group Cellular Biology of the Heart: cell-based therapies for myocardial repair and regeneration in ischemic heart disease and heart failure. Eur Heart J. 2016 06 14; 37(23):1789-98. PMID: 27055812.
      View in: PubMed
    36. Willerson JT. Focus on ECGs: A New Feature of the Texas Heart Institute Journal. Tex Heart Inst J. 2016 Feb; 43(1):1. PMID: 27047275.
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    37. Angelini P, Willerson JT. Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest and the New Policy for Involving Schoolchildren. Tex Heart Inst J. 2015 Dec; 42(6):508-9. PMID: 26664299.
      View in: PubMed
    38. Taylor DA, Perin EC, Willerson JT, Zierold C, Resende M, Carlson M, Nestor B, Wise E, Orozco A, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Traverse JH, Cooke JP, Schutt RC, Bhatnagar A, Grant MB, Lai D, Johnstone BH, Sayre SL, Moyé L, Ebert RF, Bolli R, Simari RD, Cogle CR. Identification of Bone Marrow Cell Subpopulations Associated With Improved Functional Outcomes in Patients With Chronic Left Ventricular Dysfunction: An Embedded Cohort Evaluation of the FOCUS-CCTRN Trial. Cell Transplant. 2016; 25(9):1675-1687. PMID: 26590374.
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    39. Willerson JT. In Memoriam: Kanu Chatterjee, MD (1934–2015). Tex Heart Inst J. 2015 Aug; 42(4):303-4. PMID: 26668982.
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    40. Angelini P, Uribe C, Monge J, Tobis JM, Elayda MA, Willerson JT. Origin of the right coronary artery from the opposite sinus of Valsalva in adults: characterization by intravascular ultrasonography at baseline and after stent angioplasty. Catheter Cardiovasc Interv. 2015 Aug; 86(2):199-208. PMID: 26178792.
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    41. Perin EC, Borow KM, Silva GV, DeMaria AN, Marroquin OC, Huang PP, Traverse JH, Krum H, Skerrett D, Zheng Y, Willerson JT, Itescu S, Henry TD. A Phase II Dose-Escalation Study of Allogeneic Mesenchymal Precursor Cells in Patients With Ischemic or Nonischemic Heart Failure. Circ Res. 2015 Aug 28; 117(6):576-84. PMID: 26148930.
      View in: PubMed
    42. Gizzatov A, Hernández-Rivera M, Keshishian V, Mackeyev Y, Law JJ, Guven A, Sethi R, Qu F, Muthupillai R, Cabreira-Hansen Mda G, Willerson JT, Perin EC, Ma Q, Bryant RG, Wilson LJ. Surfactant-free Gd(3+)-ion-containing carbon nanotube MRI contrast agents for stem cell labeling. Nanoscale. 2015 Jul 28; 7(28):12085-91. PMID: 26119138.
      View in: PubMed
    43. Willerson JT, Cooley DA, Rasekh A, Hall RJ. In memoriam: Ali Massumi, MD (1945-2015). Tex Heart Inst J. 2015 Jun; 42(3):191-2. PMID: 26387153.
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    44. Willerson JT, Cabreira-Hansen MG, Taylor DA, Perin EC. Changing of the guard? Eur Heart J. 2015 Jul 14; 36(27):1711-3. PMID: 26022009.
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    45. Sánchez PL, Fernández-Santos ME, Costanza S, Climent AM, Moscoso I, Gonzalez-Nicolas MA, Sanz-Ruiz R, Rodríguez H, Kren SM, Garrido G, Escalante JL, Bermejo J, Elizaga J, Menarguez J, Yotti R, Pérez del Villar C, Espinosa MA, Guillem MS, Willerson JT, Bernad A, Matesanz R, Taylor DA, Fernández-Avilés F. Acellular human heart matrix: A critical step toward whole heart grafts. Biomaterials. 2015 Aug; 61:279-89. PMID: 26005766.
      View in: PubMed
    46. Morikawa Y, Zhang M, Heallen T, Leach J, Tao G, Xiao Y, Bai Y, Li W, Willerson JT, Martin JF. Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice. Sci Signal. 2015 May 05; 8(375):ra41. PMID: 25943351.
      View in: PubMed
    47. Willerson JT. Stem cell therapy for cardiovascular diseases: a progressive journey. Curr Opin Cardiol. 2015 May; 30(3):205-12. PMID: 25695897.
      View in: PubMed
    48. Willerson JT. In memoriam: Joseph K. Perloff (1924–2014). Tex Heart Inst J. 2015 Apr; 42(2):103-4. PMID: 26054085.
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    49. Madonna R, Ferdinandy P, De Caterina R, Willerson JT, Marian AJ. Recent developments in cardiovascular stem cells. Circ Res. 2014 Dec 05; 115(12):e71-8. PMID: 25477490.
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    50. Schutt RC, Trachtenberg BH, Cooke JP, Traverse JH, Henry TD, Pepine CJ, Willerson JT, Perin EC, Ellis SG, Zhao DX, Bhatnagar A, Johnstone BH, Lai D, Resende M, Ebert RF, Wu JC, Sayre SL, Orozco A, Zierold C, Simari RD, Moyé L, Cogle CR, Taylor DA. Bone marrow characteristics associated with changes in infarct size after STEMI: a biorepository evaluation from the CCTRN TIME trial. Circ Res. 2015 Jan 02; 116(1):99-107. PMID: 25406300.
      View in: PubMed
    51. Willerson JT, Taylor D, Perin EC. Till truth makes all things plain: human hearts and stem cells. Circ Res. 2014 Nov 07; 115(11):908-10. PMID: 25378531.
      View in: PubMed
    52. Cogle CR, Wise E, Meacham AM, Zierold C, Traverse JH, Henry TD, Perin EC, Willerson JT, Ellis SG, Carlson M, Zhao DX, Bolli R, Cooke JP, Anwaruddin S, Bhatnagar A, da Graca Cabreira-Hansen M, Grant MB, Lai D, Moyé L, Ebert RF, Olson RE, Sayre SL, Schulman IH, Bosse RC, Scott EW, Simari RD, Pepine CJ, Taylor DA. Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. Circ Res. 2014 Oct 24; 115(10):867-74. PMID: 25136078.
      View in: PubMed
    53. Haidari M, Zhang W, Willerson JT, Dixon RA. Disruption of endothelial adherens junctions by high glucose is mediated by protein kinase C-ß-dependent vascular endothelial cadherin tyrosine phosphorylation. Cardiovasc Diabetol. 2014 Jul 15; 13:105. PMID: 25927959.
      View in: PubMed
    54. Perin EC, Sanz-Ruiz R, Sánchez PL, Lasso J, Pérez-Cano R, Alonso-Farto JC, Pérez-David E, Fernández-Santos ME, Serruys PW, Duckers HJ, Kastrup J, Chamuleau S, Zheng Y, Silva GV, Willerson JT, Fernández-Avilés F. Adipose-derived regenerative cells in patients with ischemic cardiomyopathy: The PRECISE Trial. Am Heart J. 2014 Jul; 168(1):88-95.e2. PMID: 24952864.
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    55. Cooley DA, Willerson JT. In memoriam: Mavis P. Kelsey, Sr. (1912-2013). Tex Heart Inst J. 2014 Apr; 41(2):121-2. PMID: 24919213.
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    56. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Ellis SG. One-year follow-up of intracoronary stem cell delivery on left ventricular function following ST-elevation myocardial infarction. JAMA. 2014 Jan 15; 311(3):301-2. PMID: 24247415.
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    57. Heallen T, Morikawa Y, Leach J, Tao G, Willerson JT, Johnson RL, Martin JF. Hippo signaling impedes adult heart regeneration. Development. 2013 Dec; 140(23):4683-90. PMID: 24255096.
      View in: PubMed
    58. Chen SN, Gurha P, Lombardi R, Ruggiero A, Willerson JT, Marian AJ. The hippo pathway is activated and is a causal mechanism for adipogenesis in arrhythmogenic cardiomyopathy. Circ Res. 2014 Jan 31; 114(3):454-68. PMID: 24276085.
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    59. Tran LA, Hernández-Rivera M, Berlin AN, Zheng Y, Sampaio L, Bové C, Cabreira-Hansen Mda G, Willerson JT, Perin EC, Wilson LJ. The use of gadolinium-carbon nanostructures to magnetically enhance stem cell retention for cellular cardiomyoplasty. Biomaterials. 2014 Jan; 35(2):720-6. PMID: 24148239.
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    60. Rivera EJ, Tran LA, Hernández-Rivera M, Yoon D, Mikos AG, Rusakova IA, Cheong BY, Cabreira-Hansen MD, Willerson JT, Perin EC, Wilson LJ. Bismuth@US-tubes as a Potential Contrast Agent for X-ray Imaging Applications. J Mater Chem B. 2013 Oct 07; 1(37). PMID: 24288589.
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    61. Schneider DJ, Avera ES, Bergmann SR, Braunwald E, Collen D, Frye R, Jaffe A, Kirk RJ, Ludbrook PA, Roberts R, Spector P, Vlasuk GP, Willerson JT. In memoriam: Burton E. Sobel a tribute from family, friends and colleagues October 21, 1937 - May 3, 2013. Exp Biol Med (Maywood). 2013 Oct; 238(10):1101-15. PMID: 24072785.
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    62. Virani SS, Lee VV, Brautbar A, Grove ML, Nambi V, Alam M, Elayda M, Wilson JM, Willerson JT, Boerwinkle E, Ballantyne CM. Single nucleotide polymorphisms in cholesteryl ester transfer protein gene and recurrent coronary heart disease or mortality in patients with established atherosclerosis. Am J Cardiol. 2013 Nov 01; 112(9):1287-92. PMID: 23891427.
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    63. Zhou L, Chen Z, Vanderslice P, So SP, Ruan KH, Willerson JT, Dixon RA. Endothelial-like progenitor cells engineered to produce prostacyclin rescue monocrotaline-induced pulmonary arterial hypertension and provide right ventricle benefits. Circulation. 2013 Aug 27; 128(9):982-94. PMID: 23841984.
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    64. Liu X, Terry T, Pan S, Yang Z, Willerson JT, Dixon RA, Liu Q. Osmotic drug delivery to ischemic hindlimbs and perfusion of vasculature with microfil for micro-computed tomography imaging. J Vis Exp. 2013 Jun 29; (76). PMID: 23852145.
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    65. Madonna R, Taylor DA, Geng YJ, De Caterina R, Shelat H, Perin EC, Willerson JT. Transplantation of mesenchymal cells rejuvenated by the overexpression of telomerase and myocardin promotes revascularization and tissue repair in a murine model of hindlimb ischemia. Circ Res. 2013 Sep 13; 113(7):902-14. PMID: 23780385.
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    66. Vanderslice P, Biediger RJ, Woodside DG, Brown WS, Khounlo S, Warier ND, Gundlach CW, Caivano AR, Bornmann WG, Maxwell DS, McIntyre BW, Willerson JT, Dixon RA. Small molecule agonist of very late antigen-4 (VLA-4) integrin induces progenitor cell adhesion. J Biol Chem. 2013 Jul 05; 288(27):19414-28. PMID: 23703610.
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    67. Hare JM, Bolli R, Cooke JP, Gordon DJ, Henry TD, Perin EC, March KL, Murphy MP, Pepine CJ, Simari RD, Skarlatos SI, Traverse JH, Willerson JT, Szady AD, Taylor DA, Vojvodic RW, Yang PC, Moyé LA. Phase II clinical research design in cardiology: learning the right lessons too well: observations and recommendations from the Cardiovascular Cell Therapy Research Network (CCTRN). Circulation. 2013 Apr 16; 127(15):1630-5. PMID: 23588961.
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    68. Liu X, Terry T, Pan S, Yang Z, Willerson JT, Dixon RA, Liu Q. Targeted delivery of carbaprostacyclin to ischemic hindlimbs enhances adaptive remodeling of the microvascular network. Hypertension. 2013 May; 61(5):1036-43. PMID: 23529172.
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    69. Bhavane R, Badea C, Ghaghada KB, Clark D, Vela D, Moturu A, Annapragada A, Johnson GA, Willerson JT, Annapragada A. Dual-energy computed tomography imaging of atherosclerotic plaques in a mouse model using a liposomal-iodine nanoparticle contrast agent. Circ Cardiovasc Imaging. 2013 Mar 01; 6(2):285-94. PMID: 23349231.
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    70. Angelini P, Vidovich MI, Lawless CE, Elayda MA, Lopez JA, Wolf D, Willerson JT. Preventing sudden cardiac death in athletes: in search of evidence-based, cost-effective screening. Tex Heart Inst J. 2013; 40(2):148-55. PMID: 23678212.
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    71. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Zhao DX, Ellis SG, Forder JR, Anderson RD, Hatzopoulos AK, Penn MS, Perin EC, Chambers J, Baran KW, Raveendran G, Lambert C, Lerman A, Simon DI, Vaughan DE, Lai D, Gee AP, Taylor DA, Cogle CR, Thomas JD, Olson RE, Bowman S, Francescon J, Geither C, Handberg E, Kappenman C, Westbrook L, Piller LB, Simpson LM, Baraniuk S, Loghin C, Aguilar D, Richman S, Zierold C, Spoon DB, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD. Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial. JAMA. 2012 Dec 12; 308(22):2380-9. PMID: 23129008.
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    72. Perin EC, Willerson JT. Buying new soul. J Am Coll Cardiol. 2012 Nov 20; 60(21):2250-1. PMID: 23153847.
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    73. Willerson JT, Yeh ET, Perin EC. Cytokine profile and ST-elevation myocardial infarction. Circ Res. 2012 Oct 26; 111(10):1256-7. PMID: 23104875.
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    74. Yeh ET, Willerson JT. Heparin and bone marrow-derived cell therapy: friend or foe? Circ Res. 2012 Sep 14; 111(7):819-20. PMID: 22982868.
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    75. Madonna R, Wu D, Wassler M, De Caterina R, Willerson JT, Geng YJ. Myocardin-A enhances expression of promyogenic genes without depressing telomerase activity in adipose tissue-derived mesenchymal stem cells. Int J Cardiol. 2013 Sep 10; 167(6):2912-21. PMID: 22884695.
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    76. Haidari M, Zhang W, Caivano A, Chen Z, Ganjehei L, Mortazavi A, Stroud C, Woodside DG, Willerson JT, Dixon RA. Integrin a2ß1 mediates tyrosine phosphorylation of vascular endothelial cadherin induced by invasive breast cancer cells. J Biol Chem. 2012 Sep 21; 287(39):32981-92. PMID: 22833667.
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    77. Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):13016-21. PMID: 22826236.
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    78. Friedewald VE, Hare JM, Miller LW, Walpole HT, Willerson JT, Roberts WC. The editor's roundtable: advances in stem cell therapy for treatment of cardiovascular disease. Am J Cardiol. 2012 Sep 15; 110(6):807-16. PMID: 22818841.
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    79. Chen SN, Czernuszewicz G, Tan Y, Lombardi R, Jin J, Willerson JT, Marian AJ. Human molecular genetic and functional studies identify TRIM63, encoding Muscle RING Finger Protein 1, as a novel gene for human hypertrophic cardiomyopathy. Circ Res. 2012 Sep 14; 111(7):907-19. PMID: 22821932.
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    80. Liu Q, Xi Y, Terry T, So SP, Mohite A, Zhang J, Wu G, Liu X, Cheng J, Ruan KH, Willerson JT, Dixon RA. Engineered endothelial progenitor cells that overexpress prostacyclin protect vascular cells. J Cell Physiol. 2012 Jul; 227(7):2907-16. PMID: 21938725.
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    81. Rodriguez-Porcel M, Kronenberg MW, Henry TD, Traverse JH, Pepine CJ, Ellis SG, Willerson JT, Moyé LA, Simari RD. Cell tracking and the development of cell-based therapies: a view from the Cardiovascular Cell Therapy Research Network. JACC Cardiovasc Imaging. 2012 May; 5(5):559-65. PMID: 22595165.
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    82. Perin EC, Willerson JT, Pepine CJ, Henry TD, Ellis SG, Zhao DX, Silva GV, Lai D, Thomas JD, Kronenberg MW, Martin AD, Anderson RD, Traverse JH, Penn MS, Anwaruddin S, Hatzopoulos AK, Gee AP, Taylor DA, Cogle CR, Smith D, Westbrook L, Chen J, Handberg E, Olson RE, Geither C, Bowman S, Francescon J, Baraniuk S, Piller LB, Simpson LM, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD. Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial. JAMA. 2012 Apr 25; 307(16):1717-26. PMID: 22447880.
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    83. Perin EC, Silva GV, Zheng Y, Gahremanpour A, Canales J, Patel D, Fernandes MR, Keller LH, Quan X, Coulter SA, Moore WH, Herlihy JP, Willerson JT. Randomized, double-blind pilot study of transendocardial injection of autologous aldehyde dehydrogenase-bright stem cells in patients with ischemic heart failure. Am Heart J. 2012 Mar; 163(3):415-21, 421.e1. PMID: 22424012.
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    84. Richman S, Gee AP, McKenna DH, Traverse JH, Henry TD, Fisk D, Pepine CJ, Bloom J, Willerson JT, Prater K, Zhao D, Koç JR, Anwaruddin S, Taylor DA, Cogle CR, Moyé LA, Simari RD, Skarlatos SI. Factors affecting the turnaround time for manufacturing, testing, and release of cellular therapy products prepared at multiple sites in support of multicenter cardiovascular regenerative medicine protocols: a Cardiovascular Cell Therapy Research Network (CCTRN) study. Transfusion. 2012 Oct; 52(10):2225-33. PMID: 22320233.
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    85. Virani SS, Brautbar A, Lee VV, MacArthur E, Morrison AC, Grove ML, Nambi V, Frazier L, Wilson JM, Willerson JT, Boerwinkle E, Ballantyne CM. Chromosome 9p21 single nucleotide polymorphisms are not associated with recurrent myocardial infarction in patients with established coronary artery disease. Circ J. 2012; 76(4):950-6. PMID: 22322877.
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    86. Willerson J. James Willerson: leading the Texans' fight against heart disease. Interview by Ruth Williams. Circ Res. 2012 Feb 03; 110(3):381-4. PMID: 22302753.
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    87. Geng YJ, Willerson JT. Repairing the infarcted heart with stem cells from umbilical cord stroma. Cardiology. 2011; 120(2):100-2. PMID: 22179040.
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    88. Wang J, Najjar A, Zhang S, Rabinovich B, Willerson JT, Gelovani JG, Yeh ET. Molecular imaging of mesenchymal stem cell: mechanistic insight into cardiac repair after experimental myocardial infarction. Circ Cardiovasc Imaging. 2012 Jan; 5(1):94-101. PMID: 22135400.
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    89. Traverse JH, Henry TD, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Forder JR, Byrne BJ, Hatzopoulos AK, Penn MS, Perin EC, Baran KW, Chambers J, Lambert C, Raveendran G, Simon DI, Vaughan DE, Simpson LM, Gee AP, Taylor DA, Cogle CR, Thomas JD, Silva GV, Jorgenson BC, Olson RE, Bowman S, Francescon J, Geither C, Handberg E, Smith DX, Baraniuk S, Piller LB, Loghin C, Aguilar D, Richman S, Zierold C, Bettencourt J, Sayre SL, Vojvodic RW, Skarlatos SI, Gordon DJ, Ebert RF, Kwak M, Moyé LA, Simari RD. Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial. JAMA. 2011 Nov 16; 306(19):2110-9. PMID: 22084195.
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    90. Lombardi R, da Graca Cabreira-Hansen M, Bell A, Fromm RR, Willerson JT, Marian AJ. Nuclear plakoglobin is essential for differentiation of cardiac progenitor cells to adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2011 Dec 09; 109(12):1342-53. PMID: 22021931.
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    91. Madjid M, Willerson JT. Inflammatory markers in coronary heart disease. Br Med Bull. 2011; 100:23-38. PMID: 22010105.
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    92. Perin EC, Tian M, Marini FC, Silva GV, Zheng Y, Baimbridge F, Quan X, Fernandes MR, Gahremanpour A, Young D, Paolillo V, Mukhopadhyay U, Borne AT, Uthamanthil R, Brammer D, Jackson J, Decker WK, Najjar AM, Thomas MW, Volgin A, Rabinovich B, Soghomonyan S, Jeong HJ, Rios JM, Steiner D, Robinson S, Mawlawi O, Pan T, Stafford J, Kundra V, Li C, Alauddin MM, Willerson JT, Shpall E, Gelovani JG. Imaging long-term fate of intramyocardially implanted mesenchymal stem cells in a porcine myocardial infarction model. PLoS One. 2011; 6(9):e22949. PMID: 21912635.
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    93. Perin EC, Willerson JT. CD34+ autologous human stem cells in treating refractory angina. Circ Res. 2011 Aug 05; 109(4):351-2. PMID: 21817161.
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    94. Gundlach CW, Caivano A, Cabreira-Hansen Mda G, Gahremanpour A, Brown WS, Zheng Y, McIntyre BW, Willerson JT, Dixon RA, Perin EC, Woodside DG. Synthesis and evaluation of an anti-MLC1 × anti-CD90 bispecific antibody for targeting and retaining bone-marrow-derived multipotent stromal cells in infarcted myocardium. Bioconjug Chem. 2011 Aug 17; 22(8):1706-14. PMID: 21749133.
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    95. Murrow J, Esteves F, Galt J, Chen J, Garcia E, Lin J, Lerakis S, Sher S, Khan Pohlel F, Waller EK, Vaughan D, Perin E, Willerson J, Kereiakes D, Preti R, Pecora AL, Quyyumi AA. Characterization of mechanical dyssynchrony measured by gated single photon emission computed tomography phase analysis after acute ST-elevation myocardial infarction. J Nucl Cardiol. 2011 Oct; 18(5):912-9. PMID: 21717276.
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    96. Rodriguez G, Ueyama T, Ogata T, Czernuszewicz G, Tan Y, Dorn GW, Bogaev R, Amano K, Oh H, Matsubara H, Willerson JT, Marian AJ. Molecular genetic and functional characterization implicate muscle-restricted coiled-coil gene (MURC) as a causal gene for familial dilated cardiomyopathy. Circ Cardiovasc Genet. 2011 Aug 01; 4(4):349-58. PMID: 21642240.
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    97. Terry T, Chen Z, Dixon RA, Vanderslice P, Zoldhelyi P, Willerson JT, Liu Q. CD34?/M-cadherin? bone marrow progenitor cells promote arteriogenesis in ischemic hindlimbs of ApoE?/? mice. PLoS One. 2011; 6(6):e20673. PMID: 21677770.
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    98. Rodriguez G, Starr AZ, Czernuszewicz GZ, Manhas A, Alhariri A, Willerson JT, Reist CJ, Pieper K, Mahaffey KW, Marian AJ, Kleiman NS. Determinants of plasma vitamin D levels in patients with acute coronary syndromes. Eur J Clin Invest. 2011 Dec; 41(12):1299-309. PMID: 21615392.
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    99. Perin EC, Silva G, Gahremanpour A, Canales J, Zheng Y, Cabreira-Hansen MG, Mendelsohn F, Chronos N, Haley R, Willerson JT, Annex BH. A randomized, controlled study of autologous therapy with bone marrow-derived aldehyde dehydrogenase bright cells in patients with critical limb ischemia. Catheter Cardiovasc Interv. 2011 Dec 01; 78(7):1060-7. PMID: 21594960.
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    100. Perin EC, Silva GV, Henry TD, Cabreira-Hansen MG, Moore WH, Coulter SA, Herlihy JP, Fernandes MR, Cheong BY, Flamm SD, Traverse JH, Zheng Y, Smith D, Shaw S, Westbrook L, Olson R, Patel D, Gahremanpour A, Canales J, Vaughn WK, Willerson JT. A randomized study of transendocardial injection of autologous bone marrow mononuclear cells and cell function analysis in ischemic heart failure (FOCUS-HF). Am Heart J. 2011 Jun; 161(6):1078-87.e3. PMID: 21641354.
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    101. Virani SS, Brautbar A, Lee VV, Elayda M, Sami S, Nambi V, Frazier L, Wilson JM, Willerson JT, Boerwinkle E, Ballantyne CM. Usefulness of single nucleotide polymorphism in chromosome 4q25 to predict in-hospital and long-term development of atrial fibrillation and survival in patients undergoing coronary artery bypass grafting. Am J Cardiol. 2011 May 15; 107(10):1504-9. PMID: 21414601.
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    102. Willerson JT. Imaging in electrical cardiac devices. J Am Coll Cardiol. 2011 Feb 15; 57(7):829-30. PMID: 21310319.
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    103. Silva GV, Fernandes MR, Cardoso CO, Sanz RR, Oliveira EM, Jimenez-Quevedo P, Lopez J, Angeli FS, Zheng Y, Willerson JT, Perin EC. A dosing study of bone marrow mononuclear cells for transendocardial injection in a pig model of chronic ischemic heart disease. Tex Heart Inst J. 2011; 38(3):219-24. PMID: 21720456.
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    104. Quyyumi AA, Waller EK, Murrow J, Esteves F, Galt J, Oshinski J, Lerakis S, Sher S, Vaughan D, Perin E, Willerson J, Kereiakes D, Gersh BJ, Gregory D, Werner A, Moss T, Chan WS, Preti R, Pecora AL. CD34(+) cell infusion after ST elevation myocardial infarction is associated with improved perfusion and is dose dependent. Am Heart J. 2011 Jan; 161(1):98-105. PMID: 21167340.
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    105. Aboshady I, Cody DD, Johnson EM, Gahremanpour A, Vela D, Khalil KG, Dupont HL, Willerson JT, Buja LM, Gladish GW. Flat-panel versus 64-channel computed tomography for in vivo quantitative characterization of aortic atherosclerotic plaques. Int J Cardiol. 2012 May 03; 156(3):295-302. PMID: 21185613.
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    106. Madonna R, De Caterina R, Willerson JT, Geng YJ. Biologic function and clinical potential of telomerase and associated proteins in cardiovascular tissue repair and regeneration. Eur Heart J. 2011 May; 32(10):1190-6. PMID: 21148539.
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    107. Tran LA, Krishnamurthy R, Muthupillai R, Cabreira-Hansen Mda G, Willerson JT, Perin EC, Wilson LJ. Gadonanotubes as magnetic nanolabels for stem cell detection. Biomaterials. 2010 Dec; 31(36):9482-91. PMID: 20965562.
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    108. Gee AP, Richman S, Durett A, McKenna D, Traverse J, Henry T, Fisk D, Pepine C, Bloom J, Willerson J, Prater K, Zhao D, Koç JR, Ellis S, Taylor D, Cogle C, Moyé L, Simari R, Skarlatos S. Multicenter cell processing for cardiovascular regenerative medicine applications: the Cardiovascular Cell Therapy Research Network (CCTRN) experience. Cytotherapy. 2010 Sep; 12(5):684-91. PMID: 20524773.
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    109. Perin EC, Silva GV, Willerson JT. Training on the use of transendocardial delivery of biologics for cardiac regeneration. JACC Cardiovasc Interv. 2010 Sep; 3(9):991. PMID: 20850103.
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    110. Nagueh SF, Lombardi R, Tan Y, Wang J, Willerson JT, Marian AJ. Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study. Eur J Clin Invest. 2010 Nov; 40(11):976-83. PMID: 20629707.
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    111. Willerson JT, Perin EC, Ellis SG, Pepine CJ, Henry TD, Zhao DX, Lai D, Penn MS, Byrne BJ, Silva G, Gee A, Traverse JH, Hatzopoulos AK, Forder JR, Martin D, Kronenberg M, Taylor DA, Cogle CR, Baraniuk S, Westbrook L, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moyé LA, Simari RD. Intramyocardial injection of autologous bone marrow mononuclear cells for patients with chronic ischemic heart disease and left ventricular dysfunction (First Mononuclear Cells injected in the US [FOCUS]): Rationale and design. Am Heart J. 2010 Aug; 160(2):215-23. PMID: 20691824.
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    112. Wang J, Zhang S, Rabinovich B, Bidaut L, Soghomonyan S, Alauddin MM, Bankson JA, Shpall E, Willerson JT, Gelovani JG, Yeh ET. Human CD34+ cells in experimental myocardial infarction: long-term survival, sustained functional improvement, and mechanism of action. Circ Res. 2010 Jun 25; 106(12):1904-11. PMID: 20448213.
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    113. Smith NL, Felix JF, Morrison AC, Demissie S, Glazer NL, Loehr LR, Cupples LA, Dehghan A, Lumley T, Rosamond WD, Lieb W, Rivadeneira F, Bis JC, Folsom AR, Benjamin E, Aulchenko YS, Haritunians T, Couper D, Murabito J, Wang YA, Stricker BH, Gottdiener JS, Chang PP, Wang TJ, Rice KM, Hofman A, Heckbert SR, Fox ER, O'Donnell CJ, Uitterlinden AG, Rotter JI, Willerson JT, Levy D, van Duijn CM, Psaty BM, Witteman JC, Boerwinkle E, Vasan RS. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):256-66. PMID: 20445134.
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    114. Kohsaka S, Kimura T, Goto M, Lee VV, Elayda M, Furukawa Y, Fukushima M, Komeda M, Sakata R, Willerson JT, Wilson JM, Kita T. Difference in patient profiles and outcomes in Japanese versus American patients undergoing coronary revascularization (collaborative study by CREDO-Kyoto and the Texas Heart Institute Research Database). Am J Cardiol. 2010 Jun 15; 105(12):1698-704. PMID: 20538117.
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    115. Morrison AC, Felix JF, Cupples LA, Glazer NL, Loehr LR, Dehghan A, Demissie S, Bis JC, Rosamond WD, Aulchenko YS, Wang YA, Haritunians T, Folsom AR, Rivadeneira F, Benjamin EJ, Lumley T, Couper D, Stricker BH, O'Donnell CJ, Rice KM, Chang PP, Hofman A, Levy D, Rotter JI, Fox ER, Uitterlinden AG, Wang TJ, Psaty BM, Willerson JT, van Duijn CM, Boerwinkle E, Witteman JC, Vasan RS, Smith NL. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. Circ Cardiovasc Genet. 2010 Jun; 3(3):248-55. PMID: 20400778.
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    116. Virani SS, Nambi V, Polsani VR, Lee VV, Elayda M, Kohsaka S, Pan W, Reul RM, Wilson JM, Petersen LA, Willerson JT, Ballantyne CM. Preoperative statin therapy decreases risk of postoperative renal insufficiency. Cardiovasc Ther. 2010 Apr; 28(2):80-6. PMID: 20398096.
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    117. El-Hamamsy I, Willerson JT, Yacoub MH. Preserved homograft function 32 years after surgery in a young patient. J Thorac Cardiovasc Surg. 2010 Jun; 139(6):e141-2. PMID: 20338596.
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    118. Simari RD, Moyé LA, Skarlatos SI, Ellis SG, Zhao DX, Willerson JT, Henry TD, Pepine CJ. Development of a network to test strategies in cardiovascular cell delivery: the NHLBI-sponsored Cardiovascular Cell Therapy Research Network (CCTRN). J Cardiovasc Transl Res. 2010 Feb; 3(1):30-6. PMID: 20445812.
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    119. Friedewald VE, Cohn LH, Kelly JP, Roberts R, Wesson DE, Willerson JT, Yancy CW, Roberts WC. The Editor's Roundtable: Health reform and its implications for cardiovascular medicine. Am J Cardiol. 2010 Feb 15; 105(4):557-65. PMID: 20152254.
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    120. Willerson JT. Texas Heart Institute Medal and The Ray C. Fish Award for Scientific Achievement in Cardiovascular Diseases. Tex Heart Inst J. 2010; 37(1):1-2. PMID: 20200620.
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    121. Sami S, Willerson JT. Contemporary treatment of unstable angina and non-ST-segment-elevation myocardial infarction (part 2). Tex Heart Inst J. 2010; 37(3):262-75. PMID: 20548800.
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    122. Ruan CH, Dixon RA, Willerson JT, Ruan KH. Prostacyclin therapy for pulmonary arterial hypertension. Tex Heart Inst J. 2010; 37(4):391-9. PMID: 20844610.
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    123. Madjid M, Ali M, Willerson JT. Lipoprotein-associated phospholipase A2 as a novel risk marker for cardiovascular disease: a systematic review of the literature. Tex Heart Inst J. 2010; 37(1):25-39. PMID: 20200624.
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    124. Traverse JH, Henry TD, Vaughan DE, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Simpson LM, Penn MS, Byrne BJ, Perin EC, Gee AP, Hatzopoulos AK, McKenna DH, Forder JR, Taylor DA, Cogle CR, Baraniuk S, Olson RE, Jorgenson BC, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moyè LA, Simari RD. LateTIME: a phase-II, randomized, double-blinded, placebo-controlled, pilot trial evaluating the safety and effect of administration of bone marrow mononuclear cells 2 to 3 weeks after acute myocardial infarction. Tex Heart Inst J. 2010; 37(4):412-20. PMID: 20844613.
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    125. Sami S, Willerson JT. Contemporary treatment of unstable angina and non-ST-segment-elevation myocardial infarction (part 1). Tex Heart Inst J. 2010; 37(2):141-8. PMID: 20401284.
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    126. Chen SN, Cilingiroglu M, Todd J, Lombardi R, Willerson JT, Gotto AM, Ballantyne CM, Marian AJ. Candidate genetic analysis of plasma high-density lipoprotein-cholesterol and severity of coronary atherosclerosis. BMC Med Genet. 2009 Oct 30; 10:111. PMID: 19878569.
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    127. Ridker PM, MacFadyen JG, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ. Number needed to treat with rosuvastatin to prevent first cardiovascular events and death among men and women with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein: justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin (JUPITER). Circ Cardiovasc Qual Outcomes. 2009 Nov; 2(6):616-23. PMID: 20031900.
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    128. Yang YJ, Qian HY, Huang J, Li JJ, Gao RL, Dou KF, Yang GS, Willerson JT, Geng YJ. Combined therapy with simvastatin and bone marrow-derived mesenchymal stem cells increases benefits in infarcted swine hearts. Arterioscler Thromb Vasc Biol. 2009 Dec; 29(12):2076-82. PMID: 19762786.
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    129. Traverse JH, Henry TD, Vaughan DE, Vaughn DE, Ellis SG, Pepine CJ, Willerson JT, Zhao DX, Piller LB, Penn MS, Byrne BJ, Perin EC, Gee AP, Hatzopoulos AK, McKenna DH, Forder JR, Taylor DA, Cogle CR, Olson RE, Jorgenson BC, Sayre SL, Vojvodic RW, Gordon DJ, Skarlatos SI, Moye' LA, Simari RD. Rationale and design for TIME: A phase II, randomized, double-blind, placebo-controlled pilot trial evaluating the safety and effect of timing of administration of bone marrow mononuclear cells after acute myocardial infarction. Am Heart J. 2009 Sep; 158(3):356-63. PMID: 19699857.
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    130. Liu Q, Chen Z, Terry T, McNatt JM, Willerson JT, Zoldhelyi P. Intra-arterial transplantation of adult bone marrow cells restores blood flow and regenerates skeletal muscle in ischemic limbs. Vasc Endovascular Surg. 2009 Oct-Nov; 43(5):433-43. PMID: 19628514.
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    131. Madonna R, Shelat H, Xue Q, Willerson JT, De Caterina R, Geng YJ. Erythropoietin protects myocardin-expressing cardiac stem cells against cytotoxicity of tumor necrosis factor-alpha. Exp Cell Res. 2009 Oct 15; 315(17):2921-8. PMID: 19631208.
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    132. Willerson JT. Myocardial perfusion scintigraphy and value in patients with non-ST segment elevation acute coronary syndromes. Am J Cardiol. 2009 Sep 01; 104(5):738. PMID: 19699355.
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    133. Ridker PM, Friedewald VE, Davidson MH, Willerson JT, Roberts WC. The editor's roundtable: the JUPITER trial--initial results and clinical implications. Am J Cardiol. 2009 May 15; 103(10):1417-25. PMID: 19427439.
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    134. Chen CH, Dixon RA, Ke LY, Willerson JT. Vascular progenitor cells in diabetes mellitus: roles of Wnt signaling and negatively charged low-density lipoprotein. Circ Res. 2009 May 08; 104(9):1038-40. PMID: 19423862.
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    135. Guo DC, Papke CL, Tran-Fadulu V, Regalado ES, Avidan N, Johnson RJ, Kim DH, Pannu H, Willing MC, Sparks E, Pyeritz RE, Singh MN, Dalman RL, Grotta JC, Marian AJ, Boerwinkle EA, Frazier LQ, LeMaire SA, Coselli JS, Estrera AL, Safi HJ, Veeraraghavan S, Muzny DM, Wheeler DA, Willerson JT, Yu RK, Shete SS, Scherer SE, Raman CS, Buja LM, Milewicz DM. Mutations in smooth muscle alpha-actin (ACTA2) cause coronary artery disease, stroke, and Moyamoya disease, along with thoracic aortic disease. Am J Hum Genet. 2009 May; 84(5):617-27. PMID: 19409525.
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    136. Brautbar A, Ballantyne CM, Lawson K, Nambi V, Chambless L, Folsom AR, Willerson JT, Boerwinkle E. Impact of adding a single allele in the 9p21 locus to traditional risk factors on reclassification of coronary heart disease risk and implications for lipid-modifying therapy in the Atherosclerosis Risk in Communities study. Circ Cardiovasc Genet. 2009 Jun; 2(3):279-85. PMID: 20031596.
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    137. Lombardi R, Dong J, Rodriguez G, Bell A, Leung TK, Schwartz RJ, Willerson JT, Brugada R, Marian AJ. Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2009 May 08; 104(9):1076-84. PMID: 19359597.
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    138. Glynn RJ, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Ridker PM. A randomized trial of rosuvastatin in the prevention of venous thromboembolism. N Engl J Med. 2009 Apr 30; 360(18):1851-61. PMID: 19329822.
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    139. Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, Macfadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ. Reduction in C-reactive protein and LDL cholesterol and cardiovascular event rates after initiation of rosuvastatin: a prospective study of the JUPITER trial. Lancet. 2009 Apr 04; 373(9670):1175-82. PMID: 19329177.
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    140. Lombardi R, Rodriguez G, Chen SN, Ripplinger CM, Li W, Chen J, Willerson JT, Betocchi S, Wickline SA, Efimov IR, Marian AJ. Resolution of established cardiac hypertrophy and fibrosis and prevention of systolic dysfunction in a transgenic rabbit model of human cardiomyopathy through thiol-sensitive mechanisms. Circulation. 2009 Mar 17; 119(10):1398-407. PMID: 19255346.
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    141. Frazier L, Vaughn WK, Willerson JT, Ballantyne CM, Boerwinkle E. Inflammatory protein levels and depression screening after coronary stenting predict major adverse coronary events. Biol Res Nurs. 2009 Oct; 11(2):163-73. PMID: 19251718.
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    142. Eichstaedt HC, Liu Q, Chen Z, Bobustuc GC, Terry T, Willerson JT, Zoldhelyi P. Gene transfer of COX-1 improves lumen size and blood flow in carotid bypass grafts. J Surg Res. 2010 Jun 01; 161(1):162-7. PMID: 19361808.
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    143. Willerson JT, Cable G, Yeh ET. PROCLAIM: pilot study to examine the effects of clopidogrel on inflammatory markers in patients with metabolic syndrome receiving low-dose aspirin. Tex Heart Inst J. 2009; 36(6):530-9. PMID: 20069077.
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    144. Virani SS, Nambi V, Lee VV, Elayda MA, Pan W, Petersen LA, Wilson JM, Willerson JT, Ballantyne CM. Obesity: an independent predictor of in-hospital postoperative renal insufficiency among patients undergoing cardiac surgery? Tex Heart Inst J. 2009; 36(6):540-5. PMID: 20069078.
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    145. Friedewald VE, Ambrose JA, Stone GW, Roberts WC, Willerson JT. The editor's roundtable: the vulnerable plaque. Am J Cardiol. 2008 Dec 15; 102(12):1644-53. PMID: 19064018.
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    146. Vela DC, Silva GV, Assad JA, Sousa AL, Coulter S, Fernandes MR, Perin EC, Willerson JT, Buja LM. Histopathological study of healing after allogenic mesenchymal stem cell delivery in myocardial infarction in dogs. J Histochem Cytochem. 2009 Feb; 57(2):167-76. PMID: 19001635.
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    147. Ridker PM, Danielson E, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Koenig W, Libby P, Lorenzatti AJ, MacFadyen JG, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med. 2008 Nov 20; 359(21):2195-207. PMID: 18997196.
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    148. Morrison AC, Bare LA, Luke MM, Pankow JS, Mosley TH, Devlin JJ, Willerson JT, Boerwinkle E. Single nucleotide polymorphisms associated with coronary heart disease predict incident ischemic stroke in the atherosclerosis risk in communities study. Cerebrovasc Dis. 2008; 26(4):420-4. PMID: 18799872.
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    149. Musunuru K, Kral BG, Blumenthal RS, Fuster V, Campbell CY, Gluckman TJ, Lange RA, Topol EJ, Willerson JT, Desai MY, Davidson MH, Mora S. The use of high-sensitivity assays for C-reactive protein in clinical practice. Nat Clin Pract Cardiovasc Med. 2008 Oct; 5(10):621-35. PMID: 18711404.
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    150. Jiménez-Quevedo P, Silva GV, Sanz-Ruiz R, Oliveira EM, Fernandes MR, Angeli F, Willerson JT, Dohmann HF, Perin EC. [Diabetic and nondiabetic patients respond differently to transendocardial injection of bone marrow mononuclear cells: findings from prospective clinical trials in "no-option" patients]. Rev Esp Cardiol. 2008 Jun; 61(6):635-9. PMID: 18570786.
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    151. Willerson JT. Passing of the editorship to Dr. James Willerson. Tex Heart Inst J. 2008; 35(1):2. PMID: 18427642.
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    152. Gertz SD, Bodmann BG, Vela D, Papadakis M, Aboshady I, Cherukuri P, Alexander S, Kouri DJ, Baid S, Gittens AA, Gladish GW, Conyers JL, Cody DD, Gavish L, Mazraeshahi RM, Wilner WT, Frazier L, Madjid M, Zarrabi A, Lukovenkov S, Ahmed A, Willerson JT, Casscells SW. Three-dimensional isotropic wavelets for post-acquisitional extraction of latent images of atherosclerotic plaque components from micro-computed tomography of human coronary arteries. Acad Radiol. 2007 Dec; 14(12):1509-19. PMID: 18035280.
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    153. Wilner WT, Mazraeshahi RM, Aboshady I, Bodmann BG, Papadakis M, Kouri D, Conyers JL, Cherukuri P, Vela D, Gladish G, Gavish L, Cody DD, Frazier L, Lukovenkov S, Madjid M, Zarrabi A, Ahmed A, Willerson JT, Casscells SW, Gertz SD. Quantification of roughness of calcific deposits in computed tomography scans of human coronary arteries. Invest Radiol. 2007 Nov; 42(11):771-6. PMID: 18030200.
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    154. Ridker PM, Fonseca FA, Genest J, Gotto AM, Kastelein JJ, Khurmi NS, Koenig W, Libby P, Lorenzatti AJ, Nordestgaard BG, Shepherd J, Willerson JT, Glynn RJ. Baseline characteristics of participants in the JUPITER trial, a randomized placebo-controlled primary prevention trial of statin therapy among individuals with low low-density lipoprotein cholesterol and elevated high-sensitivity C-reactive protein. Am J Cardiol. 2007 Dec 01; 100(11):1659-64. PMID: 18036365.
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    155. Perin EC, Silva GV, Assad JA, Vela D, Buja LM, Sousa AL, Litovsky S, Lin J, Vaughn WK, Coulter S, Fernandes MR, Willerson JT. Comparison of intracoronary and transendocardial delivery of allogeneic mesenchymal cells in a canine model of acute myocardial infarction. J Mol Cell Cardiol. 2008 Mar; 44(3):486-95. PMID: 18061611.
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    156. Madonna R, Willerson JT, Geng YJ. Myocardin a enhances telomerase activities in adipose tissue mesenchymal cells and embryonic stem cells undergoing cardiovascular myogenic differentiation. Stem Cells. 2008 Jan; 26(1):202-11. PMID: 17916802.
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    157. Bare LA, Morrison AC, Rowland CM, Shiffman D, Luke MM, Iakoubova OA, Kane JP, Malloy MJ, Ellis SG, Pankow JS, Willerson JT, Devlin JJ, Boerwinkle E. Five common gene variants identify elevated genetic risk for coronary heart disease. Genet Med. 2007 Oct; 9(10):682-9. PMID: 18073581.
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    158. Morrison AC, Bare LA, Chambless LE, Ellis SG, Malloy M, Kane JP, Pankow JS, Devlin JJ, Willerson JT, Boerwinkle E. Prediction of coronary heart disease risk using a genetic risk score: the Atherosclerosis Risk in Communities Study. Am J Epidemiol. 2007 Jul 01; 166(1):28-35. PMID: 17443022.
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    159. Madjid M, Toutouzas K, Stefanadis C, Willerson JT, Casscells SW. Coronary thermography for detection of vulnerable plaques. J Nucl Cardiol. 2007 Apr; 14(2):244-9. PMID: 17386387.
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    160. Kohsaka S, Volcik KA, Folsom AR, Wu KK, Ballantyne CM, Willerson JT, Boerwinkle E. Increased risk of incident stroke associated with the cyclooxygenase 2 (COX-2) G-765C polymorphism in African-Americans: the Atherosclerosis Risk in Communities Study. Atherosclerosis. 2008 Feb; 196(2):926-30. PMID: 17350020.
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    161. Osio A, Tan L, Chen SN, Lombardi R, Nagueh SF, Shete S, Roberts R, Willerson JT, Marian AJ. Myozenin 2 is a novel gene for human hypertrophic cardiomyopathy. Circ Res. 2007 Mar 30; 100(6):766-8. PMID: 17347475.
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    162. Vela D, Buja LM, Madjid M, Burke A, Naghavi M, Willerson JT, Casscells SW, Litovsky S. The role of periadventitial fat in atherosclerosis. Arch Pathol Lab Med. 2007 Mar; 131(3):481-7. PMID: 17516753.
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    163. Zhang S, Shpall E, Willerson JT, Yeh ET. Fusion of human hematopoietic progenitor cells and murine cardiomyocytes is mediated by alpha 4 beta 1 integrin/vascular cell adhesion molecule-1 interaction. Circ Res. 2007 Mar 16; 100(5):693-702. PMID: 17303762.
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    164. Geng YJ, Yang YJ, Casscells SW, Willerson JT. Vascular stem cells: a new concept in the pathogenesis of atherosclerosis and interventions for coronary heart disease. Future Cardiol. 2006 Sep; 2(5):585-92. PMID: 19804196.
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    165. Assali AR, Moustapha A, Sdringola S, Denktas AE, Willerson JT, Holmes DR, Smalling RW. Acute coronary syndrome may occur with in-stent restenosis and is associated with adverse outcomes (the PRESTO trial). Am J Cardiol. 2006 Sep 15; 98(6):729-33. PMID: 16950172.
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    166. Garcia-Gras E, Lombardi R, Giocondo MJ, Willerson JT, Schneider MD, Khoury DS, Marian AJ. Suppression of canonical Wnt/beta-catenin signaling by nuclear plakoglobin recapitulates phenotype of arrhythmogenic right ventricular cardiomyopathy. J Clin Invest. 2006 Jul; 116(7):2012-21. PMID: 16823493.
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    167. Madjid M, Willerson JT, Casscells SW. Intracoronary thermography for detection of high-risk vulnerable plaques. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C80-5. PMID: 16631514.
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    168. Tsimikas S, Willerson JT, Ridker PM. C-reactive protein and other emerging blood biomarkers to optimize risk stratification of vulnerable patients. J Am Coll Cardiol. 2006 Apr 18; 47(8 Suppl):C19-31. PMID: 16631506.
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    169. Singh M, Williams BA, Gersh BJ, McClelland RL, Ho KK, Willerson JT, Penny WF, Cutlip DE, Holmes DR. Geographical differences in the rates of angiographic restenosis and ischemia-driven target vessel revascularization after percutaneous coronary interventions: results from the Prevention of Restenosis With Tranilast and its Outcomes (PRESTO) Trial. J Am Coll Cardiol. 2006 Jan 03; 47(1):34-9. PMID: 16386661.
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    170. Gertz SD, Cherukuri P, Bodmann BG, Gladish G, Wilner WT, Conyers JL, Aboshady I, Madjid M, Vela D, Lukovenkov S, Papadakis M, Kouri D, Mazraeshahi RM, Frazier L, Zarrabi A, Elrod D, Willerson JT, Casscells SW. Usefulness of multidetector computed tomography for noninvasive evaluation of coronary arteries in asymptomatic patients. Am J Cardiol. 2006 Jan 15; 97(2):287-93. PMID: 16442381.
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    171. Willerson JT, Yeh ET, Geng YJ, Perin EC. Blood-derived progenitor cells after recanalization of chronic coronary artery occlusions in humans. Circ Res. 2005 Oct 14; 97(8):735-6. PMID: 16224072.
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    172. Calabro P, Chang DW, Willerson JT, Yeh ET. Release of C-reactive protein in response to inflammatory cytokines by human adipocytes: linking obesity to vascular inflammation. J Am Coll Cardiol. 2005 Sep 20; 46(6):1112-3. PMID: 16168299.
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    173. Arjomand H, Willerson JT, Holmes DR, Bamlet WR, Surabhi SK, Roukoz B, Espinoza A, McClelland RL, McCormick DJ, Goldberg S. Outcome of patients with prior percutaneous revascularization undergoing repeat coronary intervention (from the PRESTO Trial). Am J Cardiol. 2005 Sep 15; 96(6):741-6. PMID: 16169350.
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    174. Calabrò P, Samudio I, Safe SH, Willerson JT, Yeh ET. Inhibition of tumor-necrosis-factor-alpha induced endothelial cell activation by a new class of PPAR-gamma agonists. An in vitro study showing receptor-independent effects. J Vasc Res. 2005 Nov-Dec; 42(6):509-16. PMID: 16155367.
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    175. Garot P, Lefèvre T, Savage M, Louvard Y, Bamlet WR, Willerson JT, Morice MC, Holmes DR. Nine-month outcome of patients treated by percutaneous coronary interventions for bifurcation lesions in the recent era: a report from the Prevention of Restenosis with Tranilast and its Outcomes (PRESTO) trial. J Am Coll Cardiol. 2005 Aug 16; 46(4):606-12. PMID: 16098423.
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    176. Dohmann HF, Perin EC, Takiya CM, Silva GV, Silva SA, Sousa AL, Mesquita CT, Rossi MI, Pascarelli BM, Assis IM, Dutra HS, Assad JA, Castello-Branco RV, Drummond C, Dohmann HJ, Willerson JT, Borojevic R. Transendocardial autologous bone marrow mononuclear cell injection in ischemic heart failure: postmortem anatomicopathologic and immunohistochemical findings. Circulation. 2005 Jul 26; 112(4):521-6. PMID: 16027258.
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    177. Senthil V, Chen SN, Tsybouleva N, Halder T, Nagueh SF, Willerson JT, Roberts R, Marian AJ. Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ Res. 2005 Aug 05; 97(3):285-92. PMID: 16020756.
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    178. Chen SN, Ballantyne CM, Gotto AM, Tan Y, Willerson JT, Marian AJ. A common PCSK9 haplotype, encompassing the E670G coding single nucleotide polymorphism, is a novel genetic marker for plasma low-density lipoprotein cholesterol levels and severity of coronary atherosclerosis. J Am Coll Cardiol. 2005 May 17; 45(10):1611-9. PMID: 15893176.
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    179. Liu Q, Chen ZQ, Bobustuc GC, McNatt JM, Segall H, Pan S, Willerson JT, Zoldhelyi P. Local gene transduction of cyclooxygenase-1 increases blood flow in injured atherosclerotic rabbit arteries. Circulation. 2005 Apr 12; 111(14):1833-40. PMID: 15824211.
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    180. Singh M, Gersh BJ, McClelland RL, Ho KK, Willerson JT, Penny WF, Holmes DR. Predictive factors for ischemic target vessel revascularization in the Prevention of Restenosis with Tranilast and its Outcomes (PRESTO) trial. J Am Coll Cardiol. 2005 Jan 18; 45(2):198-203. PMID: 15653015.
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    181. Silva GV, Litovsky S, Assad JA, Sousa AL, Martin BJ, Vela D, Coulter SC, Lin J, Ober J, Vaughn WK, Branco RV, Oliveira EM, He R, Geng YJ, Willerson JT, Perin EC. Mesenchymal stem cells differentiate into an endothelial phenotype, enhance vascular density, and improve heart function in a canine chronic ischemia model. Circulation. 2005 Jan 18; 111(2):150-6. PMID: 15642764.
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    182. Zhang S, Wang D, Estrov Z, Raj S, Willerson JT, Yeh ET. Both cell fusion and transdifferentiation account for the transformation of human peripheral blood CD34-positive cells into cardiomyocytes in vivo. Circulation. 2004 Dec 21; 110(25):3803-7. PMID: 15596566.
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    183. Madjid M, Awan I, Willerson JT, Casscells SW. Leukocyte count and coronary heart disease: implications for risk assessment. J Am Coll Cardiol. 2004 Nov 16; 44(10):1945-56. PMID: 15542275.
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    184. Calabro P, Samudio I, Willerson JT, Yeh ET. Resistin promotes smooth muscle cell proliferation through activation of extracellular signal-regulated kinase 1/2 and phosphatidylinositol 3-kinase pathways. Circulation. 2004 Nov 23; 110(21):3335-40. PMID: 15545519.
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    185. Best PJ, Berger PB, Davis BR, Grines CL, Sadeghi HM, Williams BA, Willerson JT, Granett JR, Holmes DR. Impact of mild or moderate chronic kidney disease on the frequency of restenosis: results from the PRESTO trial. J Am Coll Cardiol. 2004 Nov 02; 44(9):1786-91. PMID: 15519008.
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    186. Popp RJ, Smith SC, Adams RJ, Antman EM, Kavey RE, DeMaria AN, Ohman EM, Pitt B, Willerson JT, Bellande BJ, Fonarow GC, Nishimura RA, Shah PM, Hirshfeld JW, Messer JV, Peterson ED, Prystowsky EN, Anderson JL, Cheitlin MD, Goldstein LB, Grant AO, Beller GA, Hines EF, Livingston DW, McEntree CW. ACCF/AHA consensus conference report on professionalism and ethics. Circulation. 2004 Oct 19; 110(16):2506-49. PMID: 15492331.
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    187. Califf RM, Nissen SE, DeMaria AN, Ohman EM, Pitt B, Willerson JT, Bilheimer DW, Cohn JN, Feigal DW, Hampson L, Lorell BH, Pepine CJ, Popp RL. Task force 2: Investigator participation in clinical research. J Am Coll Cardiol. 2004 Oct 19; 44(8):1729-36. PMID: 15489116.
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    188. Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Silva GV, Mesquita CT, Belém L, Vaughn WK, Rangel FO, Assad JA, Carvalho AC, Branco RV, Rossi MI, Dohmann HJ, Willerson JT. Improved exercise capacity and ischemia 6 and 12 months after transendocardial injection of autologous bone marrow mononuclear cells for ischemic cardiomyopathy. Circulation. 2004 Sep 14; 110(11 Suppl 1):II213-8. PMID: 15364865.
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    189. Orford JL, Denktas AE, Williams BA, Fasseas P, Willerson JT, Berger PB, Holmes DR. Routine intravascular ultrasound scanning guidance of coronary stenting is not associated with improved clinical outcomes. Am Heart J. 2004 Sep; 148(3):501-6. PMID: 15389239.
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    190. Madjid M, Zarrabi A, Litovsky S, Willerson JT, Casscells W. Finding vulnerable atherosclerotic plaques: is it worth the effort? Arterioscler Thromb Vasc Biol. 2004 Oct; 24(10):1775-82. PMID: 15308556.
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    191. Libby P, Willerson JT, Braunwald E. C-reactive protein and coronary heart disease. N Engl J Med. 2004 Jul 15; 351(3):295-8; author reply 295-8. PMID: 15257564.
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    192. Kereiakes DJ, Willerson JT. Medical technology development and approval: the future is now. Circulation. 2004 Jun 29; 109(25):3078-80. PMID: 15226223.
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    193. Kereiakes DJ, Willerson JT. Health care on trial: America's medical malpractice crisis. Circulation. 2004 Jun 22; 109(24):2939-41. PMID: 15210609.
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    194. Willerson JT, Ridker PM. Inflammation as a cardiovascular risk factor. Circulation. 2004 Jun 01; 109(21 Suppl 1):II2-10. PMID: 15173056.
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    195. Singh M, Gersh BJ, McClelland RL, Ho KK, Willerson JT, Penny WF, Holmes DR. Clinical and angiographic predictors of restenosis after percutaneous coronary intervention: insights from the Prevention of Restenosis With Tranilast and Its Outcomes (PRESTO) trial. Circulation. 2004 Jun 08; 109(22):2727-31. PMID: 15173022.
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    196. Kereiakes DJ, Willerson JT. Doctors and hospitals: healthcare's Rubik's cube. Circulation. 2004 May 25; 109(20):2381-5. PMID: 15159328.
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    197. Kereiakes DJ, Willerson JT. US health care: entitlement or privilege? Circulation. 2004 Mar 30; 109(12):1460-2. PMID: 15051650.
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    198. Delgado RM, Nawar MA, Zewail AM, Kar B, Vaughn WK, Wu KK, Aleksic N, Sivasubramanian N, McKay K, Mann DL, Willerson JT. Cyclooxygenase-2 inhibitor treatment improves left ventricular function and mortality in a murine model of doxorubicin-induced heart failure. Circulation. 2004 Mar 23; 109(11):1428-33. PMID: 15023870.
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    199. Kereiakes DJ, Willerson JT. The United States cardiovascular care deficit. Circulation. 2004 Feb 24; 109(7):821-3. PMID: 14981013.
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    200. White HD, Willerson JT. We must use the knowledge that we have to treat patients with acute coronary syndromes. Circulation. 2004 Feb 17; 109(6):698-700. PMID: 14970103.
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    201. Willerson JT, Kereiakes DJ. Cardiac resynchronization therapy: helpful now in selected patients with CHF. Circulation. 2004 Jan 27; 109(3):308-9. PMID: 14744955.
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    202. Mathew V, Gersh BJ, Williams BA, Laskey WK, Willerson JT, Tilbury RT, Davis BR, Holmes DR. Outcomes in patients with diabetes mellitus undergoing percutaneous coronary intervention in the current era: a report from the Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial. Circulation. 2004 Feb 03; 109(4):476-80. PMID: 14732749.
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    203. Silva GV, Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Assad JA, Vaughn WK, Mesquita CT, Belém L, Carvalho AC, Dohmann HJ, Barroso do Amaral E, Coutinho J, Branco R, Oliveira E, Willerson JT. Catheter-based transendocardial delivery of autologous bone-marrow-derived mononuclear cells in patients listed for heart transplantation. Tex Heart Inst J. 2004; 31(3):214-9. PMID: 15562839.
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    204. Willerson JT. The great enemy--infectious disease. Tex Heart Inst J. 2004; 31(1):1. PMID: 15061619.
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    205. Willerson JT, Kereiakes DJ. Editors' commentary: mechanical circulatory support. Circulation. 2003 Dec 23; 108(25):3069-70. PMID: 14691021.
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    206. Kereiakes DJ, Willerson JT. Therapeutic substitution: guilty until proven innocent. Circulation. 2003 Nov 25; 108(21):2611-2. PMID: 14638525.
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    207. Willerson JT, Kereiakes DJ. Endothelial dysfunction. Circulation. 2003 Oct 28; 108(17):2060-1. PMID: 14581385.
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    208. Yeh ET, Zhang S, Wu HD, Körbling M, Willerson JT, Estrov Z. Transdifferentiation of human peripheral blood CD34+-enriched cell population into cardiomyocytes, endothelial cells, and smooth muscle cells in vivo. Circulation. 2003 Oct 28; 108(17):2070-3. PMID: 14568894.
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    209. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part II. Circulation. 2003 Oct 14; 108(15):1772-8. PMID: 14557340.
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    210. Naghavi M, Libby P, Falk E, Casscells SW, Litovsky S, Rumberger J, Badimon JJ, Stefanadis C, Moreno P, Pasterkamp G, Fayad Z, Stone PH, Waxman S, Raggi P, Madjid M, Zarrabi A, Burke A, Yuan C, Fitzgerald PJ, Siscovick DS, de Korte CL, Aikawa M, Juhani Airaksinen KE, Assmann G, Becker CR, Chesebro JH, Farb A, Galis ZS, Jackson C, Jang IK, Koenig W, Lodder RA, March K, Demirovic J, Navab M, Priori SG, Rekhter MD, Bahr R, Grundy SM, Mehran R, Colombo A, Boerwinkle E, Ballantyne C, Insull W, Schwartz RS, Vogel R, Serruys PW, Hansson GK, Faxon DP, Kaul S, Drexler H, Greenland P, Muller JE, Virmani R, Ridker PM, Zipes DP, Shah PK, Willerson JT. From vulnerable plaque to vulnerable patient: a call for new definitions and risk assessment strategies: Part I. Circulation. 2003 Oct 07; 108(14):1664-72. PMID: 14530185.
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    211. Calabró P, Willerson JT, Yeh ET. Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Circulation. 2003 Oct 21; 108(16):1930-2. PMID: 14530191.
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    212. Kereiakes DJ, Willerson JT. Metabolic syndrome epidemic. Circulation. 2003 Sep 30; 108(13):1552-3. PMID: 14517151.
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    213. Willerson JT, Kereiakes DJ. Clinical research and future improvement in clinical care: the Health Insurance Portability and Accountability Act (HIPAA) and future difficulties but optimism for the way forward. Circulation. 2003 Aug 26; 108(8):919-20. PMID: 12939242.
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    214. Kereiakes DJ, Willerson JT. Vascular brachytherapy boon or bust? Circulation. 2003 Jul 29; 108(4):389-90. PMID: 12885732.
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    215. Topol EJ, Easton D, Harrington RA, Amarenco P, Califf RM, Graffagnino C, Davis S, Diener HC, Ferguson J, Fitzgerald D, Granett J, Shuaib A, Koudstaal PJ, Theroux P, Van de Werf F, Sigmon K, Pieper K, Vallee M, Willerson JT. Randomized, double-blind, placebo-controlled, international trial of the oral IIb/IIIa antagonist lotrafiban in coronary and cerebrovascular disease. Circulation. 2003 Jul 29; 108(4):399-406. PMID: 12874182.
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    216. Chung ES, Packer M, Lo KH, Fasanmade AA, Willerson JT. Randomized, double-blind, placebo-controlled, pilot trial of infliximab, a chimeric monoclonal antibody to tumor necrosis factor-alpha, in patients with moderate-to-severe heart failure: results of the anti-TNF Therapy Against Congestive Heart Failure (ATTACH) trial. Circulation. 2003 Jul 01; 107(25):3133-40. PMID: 12796126.
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    217. Willerson JT. Editor's commentary: One size does not fit all. Circulation. 2003 May 27; 107(20):2543-4. PMID: 12777319.
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    218. Naghavi M, Madjid M, Gul K, Siadaty MS, Litovsky S, Willerson JT, Casscells SW. Thermography basket catheter: in vivo measurement of the temperature of atherosclerotic plaques for detection of vulnerable plaques. Catheter Cardiovasc Interv. 2003 May; 59(1):52-9. PMID: 12720241.
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    219. Casscells W, Naghavi M, Willerson JT. Vulnerable atherosclerotic plaque: a multifocal disease. Circulation. 2003 Apr 29; 107(16):2072-5. PMID: 12719287.
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    220. Perin EC, Dohmann HF, Borojevic R, Silva SA, Sousa AL, Mesquita CT, Rossi MI, Carvalho AC, Dutra HS, Dohmann HJ, Silva GV, Belém L, Vivacqua R, Rangel FO, Esporcatte R, Geng YJ, Vaughn WK, Assad JA, Mesquita ET, Willerson JT. Transendocardial, autologous bone marrow cell transplantation for severe, chronic ischemic heart failure. Circulation. 2003 May 13; 107(18):2294-302. PMID: 12707230.
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    221. Litovsky S, Madjid M, Zarrabi A, Casscells SW, Willerson JT, Naghavi M. Superparamagnetic iron oxide-based method for quantifying recruitment of monocytes to mouse atherosclerotic lesions in vivo: enhancement by tissue necrosis factor-alpha, interleukin-1beta, and interferon-gamma. Circulation. 2003 Mar 25; 107(11):1545-9. PMID: 12654614.
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    222. Willerson JT. Editor's commentary: centers of excellence. Circulation. 2003 Mar 25; 107(11):1471-2. PMID: 12654601.
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    223. Henry TD, Annex BH, McKendall GR, Azrin MA, Lopez JJ, Giordano FJ, Shah PK, Willerson JT, Benza RL, Berman DS, Gibson CM, Bajamonde A, Rundle AC, Fine J, McCluskey ER. The VIVA trial: Vascular endothelial growth factor in Ischemia for Vascular Angiogenesis. Circulation. 2003 Mar 18; 107(10):1359-65. PMID: 12642354.
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    224. Perin EC, Geng YJ, Willerson JT. Adult stem cell therapy in perspective. Circulation. 2003 Feb 25; 107(7):935-8. PMID: 12600902.
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    225. Yeh ET, Willerson JT. Coming of age of C-reactive protein: using inflammation markers in cardiology. Circulation. 2003 Jan 28; 107(3):370-1. PMID: 12551854.
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    226. González AA, Segura AM, Horiba K, Qian S, Yu ZX, Stetler-Stevenson W, Willerson JT, McAllister HA, Ferrans VJ. Matrix metalloproteinases and their tissue inhibitors in the lesions of cardiac and pulmonary sarcoidosis: an immunohistochemical study. Hum Pathol. 2002 Dec; 33(12):1158-64. PMID: 12514782.
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    227. Madjid M, Naghavi M, Malik BA, Litovsky S, Willerson JT, Casscells W. Thermal detection of vulnerable plaque. Am J Cardiol. 2002 Nov 21; 90(10C):36L-39L. PMID: 12459426.
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    228. Chen M, Capps C, Willerson JT, Zoldhelyi P. E2F-1 regulates nuclear factor-kappaB activity and cell adhesion: potential antiinflammatory activity of the transcription factor E2F-1. Circulation. 2002 Nov 19; 106(21):2707-13. PMID: 12438297.
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    229. Bonow R, Clark EB, Curfman GD, Guttmacher A, Hill MN, Miller DC, Morrison AR, Myerburg RJ, Schneider MD, Weisfeldt ML, Willerson JT, Young JB. Task Force on Strategic Research Direction: Clinical Science Subgroup key science topics report. Circulation. 2002 Nov 12; 106(20):e162-6. PMID: 12427671.
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    230. Lincoff AM, Califf RM, Van de Werf F, Willerson JT, White HD, Armstrong PW, Guetta V, Gibler WB, Hochman JS, Bode C, Vahanian A, Steg PG, Ardissino D, Savonitto S, Bar F, Sadowski Z, Betriu A, Booth JE, Wolski K, Waller M, Topol EJ. Mortality at 1 year with combination platelet glycoprotein IIb/IIIa inhibition and reduced-dose fibrinolytic therapy vs conventional fibrinolytic therapy for acute myocardial infarction: GUSTO V randomized trial. JAMA. 2002 Nov 06; 288(17):2130-5. PMID: 12413372.
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    231. Zarrabi A, Gul K, Willerson JT, Casscells W, Naghavi M. Intravascular thermography: a novel approach for detection of vulnerable plaque. Curr Opin Cardiol. 2002 Nov; 17(6):656-62. PMID: 12466709.
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    232. Holmes DR, Savage M, LaBlanche JM, Grip L, Serruys PW, Fitzgerald P, Fischman D, Goldberg S, Brinker JA, Zeiher AM, Shapiro LM, Willerson J, Davis BR, Ferguson JJ, Popma J, King SB, Lincoff AM, Tcheng JE, Chan R, Granett JR, Poland M. Results of Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial. Circulation. 2002 Sep 03; 106(10):1243-50. PMID: 12208800.
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    233. Naghavi M, John R, Naguib S, Siadaty MS, Grasu R, Kurian KC, van Winkle WB, Soller B, Litovsky S, Madjid M, Willerson JT, Casscells W. pH Heterogeneity of human and rabbit atherosclerotic plaques; a new insight into detection of vulnerable plaque. Atherosclerosis. 2002 Sep; 164(1):27-35. PMID: 12119190.
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    234. Pitt B, Pepine C, Willerson JT. Cyclooxygenase-2 inhibition and cardiovascular events. Circulation. 2002 Jul 09; 106(2):167-9. PMID: 12105151.
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    235. Willerson JT. Systemic and local inflammation in patients with unstable atherosclerotic plaques. Prog Cardiovasc Dis. 2002 May-Jun; 44(6):469-78. PMID: 12077720.
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    236. Wang J, Geng YJ, Guo B, Klima T, Lal BN, Willerson JT, Casscells W. Near-infrared spectroscopic characterization of human advanced atherosclerotic plaques. J Am Coll Cardiol. 2002 Apr 17; 39(8):1305-13. PMID: 11955848.
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    237. Willerson JT, Crea F. How to search for the precipitating role of vasoconstriction and its prevalence in myocardial infarction. Ital Heart J. 2002 Apr; 3(4):217-9. PMID: 12025368.
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    238. Golino P, Crea F, Willerson JT. How to study the effects of platelet aggregation and thrombosis on coronary vasomotion and their clinical relevance. Ital Heart J. 2002 Apr; 3(4):220-5. PMID: 12025369.
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    239. Willerson JT. March 26, 2002: rapid access publication. Circulation. 2002 Mar 26; 105(12):1395. PMID: 11914241.
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    240. Theroux P, Chaitman BR, Erhardt L, Jessel A, Meinertz T, Nickel WU, Schroeder JS, Tognoni G, White H, Willerson JT. Design of a trial evaluating myocardial cell protection with cariporide, an inhibitor of the transmembrane sodium-hydrogen exchanger: the Guard During Ischemia Against Necrosis (GUARDIAN) trial. Curr Control Trials Cardiovasc Med. 2000; 1(1):59-67. PMID: 11714411.
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