ERIC BOERWINKLE to Genetic Variation
This is a "connection" page, showing publications ERIC BOERWINKLE has written about Genetic Variation.
Connection Strength
8.912
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Rare variants analysis using penalization methods for whole genome sequence data. BMC Bioinformatics. 2015 Dec 04; 16:405.
Score: 0.323
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Genetic variants identified in a European genome-wide association study that were found to predict incident coronary heart disease in the atherosclerosis risk in communities study. Am J Epidemiol. 2010 Jan 01; 171(1):14-23.
Score: 0.213
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Kininogen gene (KNG) variation has a consistent effect on aldosterone response to antihypertensive drug therapy: the GERA study. Physiol Genomics. 2009 Sep 09; 39(1):56-60.
Score: 0.207
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Peroxisome proliferator-activated receptor [alpha] genetic variation interacts with n-6 and long-chain n-3 fatty acid intake to affect total cholesterol and LDL-cholesterol concentrations in the Atherosclerosis Risk in Communities Study. Am J Clin Nutr. 2008 Jun; 87(6):1926-31.
Score: 0.192
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Variation in TCF7L2 and increased risk of colon cancer: the Atherosclerosis Risk in Communities (ARIC) Study. Diabetes Care. 2008 May; 31(5):905-9.
Score: 0.188
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Interaction effects of high-density lipoprotein metabolism gene variation and alcohol consumption on coronary heart disease risk: the atherosclerosis risk in communities study. J Stud Alcohol Drugs. 2007 Jul; 68(4):485-92.
Score: 0.180
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Genetic diversity fuels gene discovery for tobacco and alcohol use. Nature. 2022 12; 612(7941):720-724.
Score: 0.131
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Rare coding variants in 35 genes associate with circulating lipid levels-A multi-ancestry analysis of 170,000 exomes. Am J Hum Genet. 2022 01 06; 109(1):81-96.
Score: 0.123
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Rare Coding Variants Associated With Electrocardiographic Intervals Identify Monogenic Arrhythmia Susceptibility Genes: A Multi-Ancestry Analysis. Circ Genom Precis Med. 2021 08; 14(4):e003300.
Score: 0.119
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Sequencing of 53,831 diverse genomes from the NHLBI TOPMed Program. Nature. 2021 Feb; 590(7845):290-299.
Score: 0.116
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A Mendelian randomization of ?' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke. Blood. 2020 12 24; 136(26):3062-3069.
Score: 0.115
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Dynamic incorporation of multiple in silico functional annotations empowers rare variant association analysis of large whole-genome sequencing studies at scale. Nat Genet. 2020 Sep; 52(9):969-983.
Score: 0.112
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Lack of association of 3 functional gene variants with hypertension in African Americans. Hypertension. 2000 Jun; 35(6):1297-300.
Score: 0.110
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A Genocentric Approach to Discovery of Mendelian Disorders. Am J Hum Genet. 2019 11 07; 105(5):974-986.
Score: 0.106
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Impact of Rare and Common Genetic Variants on Diabetes Diagnosis by Hemoglobin A1c in Multi-Ancestry Cohorts: The Trans-Omics for Precision Medicine Program. Am J Hum Genet. 2019 10 03; 105(4):706-718.
Score: 0.105
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Dynamic Scan Procedure for Detecting Rare-Variant Association Regions in Whole-Genome Sequencing Studies. Am J Hum Genet. 2019 05 02; 104(5):802-814.
Score: 0.102
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ACAT: A Fast and Powerful p Value Combination Method for Rare-Variant Analysis in Sequencing Studies. Am J Hum Genet. 2019 03 07; 104(3):410-421.
Score: 0.101
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Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nat Genet. 2019 03; 51(3):452-469.
Score: 0.101
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Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data. Hum Genet. 2019 Feb; 138(2):199-210.
Score: 0.100
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Exome Chip Analysis Identifies Low-Frequency and Rare Variants in MRPL38 for White Matter Hyperintensities on Brain Magnetic Resonance Imaging. Stroke. 2018 08; 49(8):1812-1819.
Score: 0.097
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Genome-Wide Association Study of Serum Fructosamine and Glycated Albumin in Adults Without Diagnosed Diabetes: Results From the Atherosclerosis Risk in Communities Study. Diabetes. 2018 08; 67(8):1684-1696.
Score: 0.096
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet. 2018 01; 50(1):26-41.
Score: 0.093
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Exome-wide association study of plasma lipids in >300,000 individuals. Nat Genet. 2017 Dec; 49(12):1758-1766.
Score: 0.092
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Rare and low-frequency coding variants alter human adult height. Nature. 2017 02 09; 542(7640):186-190.
Score: 0.088
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On Robust Association Testing for Quantitative Traits and Rare Variants. G3 (Bethesda). 2016 12 07; 6(12):3941-3950.
Score: 0.087
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Resolution of Disease Phenotypes Resulting from Multilocus Genomic Variation. N Engl J Med. 2017 01 05; 376(1):21-31.
Score: 0.087
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Generalization and fine mapping of European ancestry-based central adiposity variants in African ancestry populations. Int J Obes (Lond). 2017 02; 41(2):324-331.
Score: 0.086
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Genetic variants associated with risk of Alzheimer's disease contribute to cognitive change in midlife: The Atherosclerosis Risk in Communities Study. Am J Med Genet B Neuropsychiatr Genet. 2017 Apr; 174(3):269-282.
Score: 0.086
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Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci. Nat Genet. 2016 10; 48(10):1162-70.
Score: 0.085
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Identification, analysis, and interpretation of a human serum metabolomics causal network in an observational study. J Biomed Inform. 2016 10; 63:337-343.
Score: 0.085
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Loss-of-function variants influence the human serum metabolome. Sci Adv. 2016 08; 2(8):e1600800.
Score: 0.085
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Genetic Variants in LRP1 and ULK4 Are Associated with Acute Aortic Dissections. Am J Hum Genet. 2016 09 01; 99(3):762-769.
Score: 0.085
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Exome Genotyping Identifies Pleiotropic Variants Associated with Red Blood Cell Traits. Am J Hum Genet. 2016 Jul 07; 99(1):8-21.
Score: 0.084
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Platelet-Related Variants Identified by Exomechip Meta-analysis in 157,293 Individuals. Am J Hum Genet. 2016 Jul 07; 99(1):40-55.
Score: 0.084
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Identification of Rare Variants in Metabolites of the Carnitine Pathway by Whole Genome Sequencing Analysis. Genet Epidemiol. 2016 09; 40(6):486-91.
Score: 0.084
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Diagnostic Yield and Clinical Utility of Sequencing Familial Hypercholesterolemia Genes in Patients With Severe Hypercholesterolemia. J Am Coll Cardiol. 2016 06 07; 67(22):2578-89.
Score: 0.083
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Monoallelic and Biallelic Variants in EMC1 Identified in Individuals with Global Developmental Delay, Hypotonia, Scoliosis, and Cerebellar Atrophy. Am J Hum Genet. 2016 Mar 03; 98(3):562-570.
Score: 0.082
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Genes that Affect Brain Structure and Function Identified by Rare Variant Analyses of Mendelian Neurologic Disease. Neuron. 2015 Nov 04; 88(3):499-513.
Score: 0.080
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PLD3 variants in population studies. Nature. 2015 Apr 02; 520(7545):E2-3.
Score: 0.077
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Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun. 2015 Jan 29; 6:5897.
Score: 0.076
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Coronary heart disease and genetic variants with low phospholipase A2 activity. N Engl J Med. 2015 Jan 15; 372(3):295-6.
Score: 0.076
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No association of apolipoprotein A-IV codon 347 and 360 variation with atherosclerosis and lipid transport in a sample of mixed hyperlipidemics. Genet Epidemiol. 1995; 12(4):371-80.
Score: 0.076
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In silico prediction of splice-altering single nucleotide variants in the human genome. Nucleic Acids Res. 2014 Dec 16; 42(22):13534-44.
Score: 0.076
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Defining the role of common variation in the genomic and biological architecture of adult human height. Nat Genet. 2014 Nov; 46(11):1173-86.
Score: 0.075
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Sequence variation in TMEM18 in association with body mass index: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):344-9.
Score: 0.073
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Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):359-64.
Score: 0.073
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Sequencing of SCN5A identifies rare and common variants associated with cardiac conduction: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium. Circ Cardiovasc Genet. 2014 Jun; 7(3):365-73.
Score: 0.073
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Association of levels of fasting glucose and insulin with rare variants at the chromosome 11p11.2-MADD locus: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):374-382.
Score: 0.073
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Association of low-frequency and rare coding-sequence variants with blood lipids and coronary heart disease in 56,000 whites and blacks. Am J Hum Genet. 2014 Feb 06; 94(2):223-32.
Score: 0.071
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Possible race and gender divergence in association of genetic variations with plasma von Willebrand factor: a study of ARIC and 1000 genome cohorts. PLoS One. 2014; 9(1):e84810.
Score: 0.071
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The effect of variation in the apolipoprotein B gene on plasmid lipid and apolipoprotein B levels. I. A likelihood-based approach to cladistic analysis. Ann Hum Genet. 1994 01; 58(1):35-64.
Score: 0.071
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Neutral genomic regions refine models of recent rapid human population growth. Proc Natl Acad Sci U S A. 2014 Jan 14; 111(2):757-62.
Score: 0.071
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In silico tools for splicing defect prediction: a survey from the viewpoint of end users. Genet Med. 2014 Jul; 16(7):497-503.
Score: 0.070
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Common variants in Mendelian kidney disease genes and their association with renal function. J Am Soc Nephrol. 2013 Dec; 24(12):2105-17.
Score: 0.069
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Exon sequencing of PAX3 and T (brachyury) in cases with spina bifida. Birth Defects Res A Clin Mol Teratol. 2013 Sep; 97(9):597-601.
Score: 0.069
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APOL1 variants associate with increased risk of CKD among African Americans. J Am Soc Nephrol. 2013 Sep; 24(9):1484-91.
Score: 0.068
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Effects of rare and common blood pressure gene variants on essential hypertension: results from the Family Blood Pressure Program, CLUE, and Atherosclerosis Risk in Communities studies. Circ Res. 2013 Jan 18; 112(2):318-26.
Score: 0.065
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FTO genotype is associated with phenotypic variability of body mass index. Nature. 2012 Oct 11; 490(7419):267-72.
Score: 0.065
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Association of estimated glomerular filtration rate and urinary uromodulin concentrations with rare variants identified by UMOD gene region sequencing. PLoS One. 2012; 7(5):e38311.
Score: 0.063
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Evolution and functional impact of rare coding variation from deep sequencing of human exomes. Science. 2012 Jul 06; 337(6090):64-9.
Score: 0.063
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Role of apolipoprotein E and B gene variation in determining response of lipid, lipoprotein, and apolipoprotein levels to increased dietary cholesterol. Am J Hum Genet. 1991 Dec; 49(6):1145-54.
Score: 0.061
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Signal peptide-length variation in human apolipoprotein B gene. Molecular characteristics and association with plasma glucose levels. Diabetes. 1991 Nov; 40(11):1539-44.
Score: 0.061
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Genome partitioning of genetic variation for complex traits using common SNPs. Nat Genet. 2011 Jun; 43(6):519-25.
Score: 0.059
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Association studies for next-generation sequencing. Genome Res. 2011 Jul; 21(7):1099-108.
Score: 0.059
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Dissociation between APOC3 variants, hepatic triglyceride content and insulin resistance. Hepatology. 2011 Feb; 53(2):467-74.
Score: 0.057
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Common variants at 10 genomic loci influence hemoglobin A1(C) levels via glycemic and nonglycemic pathways. Diabetes. 2010 Dec; 59(12):3229-39.
Score: 0.056
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Common genetic variants associate with serum phosphorus concentration. J Am Soc Nephrol. 2010 Jul; 21(7):1223-32.
Score: 0.055
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Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge. Nat Genet. 2010 Feb; 42(2):142-8.
Score: 0.054
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MMP2 genetic variation is associated with measures of fibrous cap thickness: The Atherosclerosis Risk in Communities Carotid MRI Study. Atherosclerosis. 2010 May; 210(1):188-93.
Score: 0.053
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Variation in the checkpoint kinase 2 gene is associated with type 2 diabetes in multiple populations. Acta Diabetol. 2010 Dec; 47 Suppl 1:199-207.
Score: 0.053
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Antihypertensive pharmacogenetic effect of fibrinogen-beta variant -455G>A on cardiovascular disease, end-stage renal disease, and mortality: the GenHAT study. Pharmacogenet Genomics. 2009 Jun; 19(6):415-21.
Score: 0.051
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Common variants at ten loci modulate the QT interval duration in the QTSCD Study. Nat Genet. 2009 Apr; 41(4):407-14.
Score: 0.051
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Rapid typing of tandemly repeated hypervariable loci by the polymerase chain reaction: application to the apolipoprotein B 3' hypervariable region. Proc Natl Acad Sci U S A. 1989 Jan; 86(1):212-6.
Score: 0.050
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Comprehensive evaluation of apolipoprotein H gene (APOH) variation identifies novel associations with measures of lipid metabolism in GENOA. J Lipid Res. 2008 Dec; 49(12):2648-56.
Score: 0.049
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Carbohydrate intake modifies associations between ANGPTL4[E40K] genotype and HDL-cholesterol concentrations in White men from the Atherosclerosis Risk in Communities (ARIC) study. Atherosclerosis. 2009 Mar; 203(1):214-20.
Score: 0.048
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Common variants in the GDF5-UQCC region are associated with variation in human height. Nat Genet. 2008 Feb; 40(2):198-203.
Score: 0.047
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Interactions between the adducin 2 gene and antihypertensive drug therapies in determining blood pressure in people with hypertension. BMC Med Genet. 2007 Sep 13; 8:61.
Score: 0.046
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Genetic variations associated with echocardiographic left ventricular traits in hypertensive blacks. Hypertension. 2007 May; 49(5):992-9.
Score: 0.044
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Association between patterns of nucleotide variation across the three fibrinogen genes and plasma fibrinogen levels: the Coronary Artery Risk Development in Young Adults (CARDIA) study. J Thromb Haemost. 2006 06; 4(6):1279-87.
Score: 0.042
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Sequence variations in PCSK9, low LDL, and protection against coronary heart disease. N Engl J Med. 2006 Mar 23; 354(12):1264-72.
Score: 0.041
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Genetic variation of the renin-angiotensin system and chronic kidney disease progression in black individuals in the atherosclerosis risk in communities study. J Am Soc Nephrol. 2006 Feb; 17(2):504-12.
Score: 0.041
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Association of common and rare variants with Alzheimer's disease in more than 13,000 diverse individuals with whole-genome sequencing from the Alzheimer's Disease Sequencing Project. Alzheimers Dement. 2024 Dec; 20(12):8470-8483.
Score: 0.037
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Rare variant contribution to the heritability of coronary artery disease. Nat Commun. 2024 Oct 09; 15(1):8741.
Score: 0.037
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Whole-genome sequencing in 333,100 individuals reveals rare non-coding single variant and aggregate associations with height. Nat Commun. 2024 Oct 03; 15(1):8549.
Score: 0.037
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Tree scanning: a method for using haplotype trees in phenotype/genotype association studies. Genetics. 2005 Jan; 169(1):441-53.
Score: 0.037
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The effects of scale: variation in the APOA1/C3/A4/A5 gene cluster. Hum Genet. 2004 Jun; 115(1):36-56.
Score: 0.036
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Key variants via the Alzheimer's Disease Sequencing Project whole genome sequence data. Alzheimers Dement. 2024 05; 20(5):3290-3304.
Score: 0.036
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Multilocus effects of the renin-angiotensin-aldosterone system genes on blood pressure response to a thiazide diuretic. Pharmacogenomics J. 2004; 4(1):17-23.
Score: 0.035
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Missense Genetic Variation of ICAM1 and Incident Heart Failure. J Card Fail. 2023 08; 29(8):1163-1172.
Score: 0.033
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A framework for detecting noncoding rare-variant associations of large-scale whole-genome sequencing studies. Nat Methods. 2022 Dec; 19(12):1599-1611.
Score: 0.033
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"Into thin air" and the genetics of complex traits. Circulation. 2002 Aug 13; 106(7):768-9.
Score: 0.032
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Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism. Am J Hum Genet. 2002 Sep; 71(3):501-17.
Score: 0.032
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Sequence polymorphism at the human apolipoprotein AII gene ( APOA2): unexpected deficit of variation in an African-American sample. Hum Genet. 2002 Jul; 111(1):75-87.
Score: 0.032
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The Value of Rare Genetic Variation in the Prediction of Common Obesity in European Ancestry Populations. Front Endocrinol (Lausanne). 2022; 13:863893.
Score: 0.031
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SNP43 of CAPN10 and the risk of type 2 Diabetes in African-Americans: the Atherosclerosis Risk in Communities Study. Diabetes. 2002 Jan; 51(1):231-7.
Score: 0.031
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Population sequencing data reveal a compendium of mutational processes in the human germ line. Science. 2021 Aug 27; 373(6558):1030-1035.
Score: 0.030
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Genetic susceptibility, obesity and lifetime risk of type 2 diabetes: The ARIC study and Rotterdam Study. Diabet Med. 2021 10; 38(10):e14639.
Score: 0.030
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Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program. Am J Hum Genet. 2021 05 06; 108(5):874-893.
Score: 0.029
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Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies. Genetics. 2000 Nov; 156(3):1259-75.
Score: 0.028
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Genetic variation in the gene encoding calpain-10 is associated with type 2 diabetes mellitus. Nat Genet. 2000 Oct; 26(2):163-75.
Score: 0.028
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Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene. Genome Res. 2000 Oct; 10(10):1532-45.
Score: 0.028
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Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism. Am J Hum Genet. 2000 Oct; 67(4):881-900.
Score: 0.028
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Urine 6-Bromotryptophan: Associations with Genetic Variants and Incident End-Stage Kidney Disease. Sci Rep. 2020 06 22; 10(1):10018.
Score: 0.028
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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nat Commun. 2020 05 21; 11(1):2542.
Score: 0.028
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Glutathione S-transferase genotype as a susceptibility factor in smoking-related coronary heart disease. Atherosclerosis. 2000 Apr; 149(2):451-62.
Score: 0.027
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APOL1 Kidney Risk Variants and Cardiovascular Disease: An Individual Participant Data Meta-Analysis. J Am Soc Nephrol. 2019 10; 30(10):2027-2036.
Score: 0.026
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Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease. PLoS One. 2019; 14(5):e0216222.
Score: 0.026
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Multiple SCN5A variant enhancers modulate its cardiac gene expression and the QT interval. Proc Natl Acad Sci U S A. 2019 05 28; 116(22):10636-10645.
Score: 0.026
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Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings. Circulation. 1999 Mar 23; 99(11):1407-10.
Score: 0.025
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Linkage analysis of candidate obesity genes among the Mexican-American population of Starr County, Texas. Genet Epidemiol. 1999; 16(4):397-411.
Score: 0.025
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Genetic Variants in SGLT1, Glucose Tolerance, and Cardiometabolic Risk. J Am Coll Cardiol. 2018 10 09; 72(15):1763-1773.
Score: 0.025
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Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation. Hum Mol Genet. 1998 Sep; 7(9):1379-83.
Score: 0.024
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Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet. 1998 Aug; 63(2):595-612.
Score: 0.024
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Contributions of rare coding variants in hypotension syndrome genes to population blood pressure variation. Medicine (Baltimore). 2018 Aug; 97(33):e11865.
Score: 0.024
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DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene. Nat Genet. 1998 Jul; 19(3):233-40.
Score: 0.024
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Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males. Circulation. 1998 May 12; 97(18):1773-9.
Score: 0.024
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nat Genet. 2018 04; 50(4):559-571.
Score: 0.024
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Genetic Variation in Genes Underlying Diverse Dementias May Explain a Small Proportion of Cases in the Alzheimer's Disease Sequencing Project. Dement Geriatr Cogn Disord. 2018; 45(1-2):1-17.
Score: 0.024
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Effects of Gender-Specific Differences, Inflammatory Response, and Genetic Variation on the Associations Among Depressive Symptoms and the Risk of Major Adverse Coronary Events in Patients With Acute Coronary Syndrome. Biol Res Nurs. 2018 03; 20(2):168-176.
Score: 0.023
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The Asn9 variant of lipoprotein lipase is associated with the -93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group. Clin Genet. 1998 Jan; 53(1):27-33.
Score: 0.023
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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation. Am J Hum Genet. 2017 Dec 07; 101(6):888-902.
Score: 0.023
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Lipoprotein-associated phospholipase A2 and risk of incident peripheral arterial disease: Findings from The Atherosclerosis Risk in Communities study (ARIC). Atherosclerosis. 2018 01; 268:12-18.
Score: 0.023
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Whole-Exome Sequencing Identifies Novel Variants for Tooth Agenesis. J Dent Res. 2018 Jan; 97(1):49-59.
Score: 0.023
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Genetic variant showing a positive interaction with beta-blocking agents with a beneficial influence on lipoprotein lipase activity, HDL cholesterol, and triglyceride levels in coronary artery disease patients. The Ser447-stop substitution in the lipoprotein lipase gene. REGRESS Study Group. Circulation. 1997 Jun 17; 95(12):2628-35.
Score: 0.022
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An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans. Diabetes. 2017 11; 66(11):2888-2902.
Score: 0.022
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DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases. Genome Biol. 2016 12 12; 17(1):255.
Score: 0.022
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Discovery of Genetic Variation on Chromosome 5q22 Associated with Mortality in Heart Failure. PLoS Genet. 2016 05; 12(5):e1006034.
Score: 0.021
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Whole-Exome Sequencing in Familial Parkinson Disease. JAMA Neurol. 2016 Jan; 73(1):68-75.
Score: 0.020
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Large-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repair. Nat Genet. 2015 Nov; 47(11):1294-1303.
Score: 0.020
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A novel measure of genetic distance for highly polymorphic tandem repeat loci. Mol Biol Evol. 1995 Sep; 12(5):914-20.
Score: 0.020
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Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota. Hum Genet. 1995 Sep; 96(3):295-300.
Score: 0.020
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Exome Sequence Analysis Suggests that Genetic Burden Contributes to Phenotypic Variability and Complex Neuropathy. Cell Rep. 2015 Aug 18; 12(7):1169-83.
Score: 0.020
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Rare coding variants and X-linked loci associated with age at menarche. Nat Commun. 2015 Aug 04; 6:7756.
Score: 0.020
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Rare and low-frequency variants and their association with plasma levels of fibrinogen, FVII, FVIII, and vWF. Blood. 2015 Sep 10; 126(11):e19-29.
Score: 0.020
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Strategies to design and analyze targeted sequencing data: cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):335-43.
Score: 0.018
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Linkage analysis incorporating gene-age interactions identifies seven novel lipid loci: the Family Blood Pressure Program. Atherosclerosis. 2014 Jul; 235(1):84-93.
Score: 0.018
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Small dense low-density lipoprotein-cholesterol concentrations predict risk for coronary heart disease: the Atherosclerosis Risk In Communities (ARIC) study. Arterioscler Thromb Vasc Biol. 2014 May; 34(5):1069-77.
Score: 0.018
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Targeted sequencing in candidate genes for atrial fibrillation: the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Targeted Sequencing Study. Heart Rhythm. 2014 Mar; 11(3):452-7.
Score: 0.018
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Whole-genome sequence-based analysis of high-density lipoprotein cholesterol. Nat Genet. 2013 Aug; 45(8):899-901.
Score: 0.017
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Analysis of rare, exonic variation amongst subjects with autism spectrum disorders and population controls. PLoS Genet. 2013 Apr; 9(4):e1003443.
Score: 0.017
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Rare complete knockouts in humans: population distribution and significant role in autism spectrum disorders. Neuron. 2013 Jan 23; 77(2):235-42.
Score: 0.017
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Length and sequence variation in the apolipoprotein B intron 20 Alu repeat. Genomics. 1992 Oct; 14(2):449-54.
Score: 0.016
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Ultraconserved elements in the human genome: association and transmission analyses of highly constrained single-nucleotide polymorphisms. Genetics. 2012 Sep; 192(1):253-66.
Score: 0.016
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Measuring alcohol consumption for genomic meta-analyses of alcohol intake: opportunities and challenges. Am J Clin Nutr. 2012 Mar; 95(3):539-47.
Score: 0.015
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Clan genomics and the complex architecture of human disease. Cell. 2011 Sep 30; 147(1):32-43.
Score: 0.015
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A genome-wide association study identifies LIPA as a susceptibility gene for coronary artery disease. Circ Cardiovasc Genet. 2011 Aug 01; 4(4):403-12.
Score: 0.015
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Genetic variation of glucose transporter-1 (GLUT1) and albuminuria in 10,278 European Americans and African Americans: a case-control study in the Atherosclerosis Risk in Communities (ARIC) study. BMC Med Genet. 2011 Jan 19; 12:16.
Score: 0.014
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Genetic variation at the apolipoprotein gene loci contribute to response of plasma lipids to dietary change. Genet Epidemiol. 1990; 7(4):261-75.
Score: 0.013
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Genome-wide association studies of MRI-defined brain infarcts: meta-analysis from the CHARGE Consortium. Stroke. 2010 Feb; 41(2):210-7.
Score: 0.013
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Meta-analysis of genome-wide association data identifies two loci influencing age at menarche. Nat Genet. 2009 Jun; 41(6):648-50.
Score: 0.013
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Multiple loci associated with indices of renal function and chronic kidney disease. Nat Genet. 2009 Jun; 41(6):712-7.
Score: 0.013
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Rare loss-of-function mutations in ANGPTL family members contribute to plasma triglyceride levels in humans. J Clin Invest. 2009 Jan; 119(1):70-9.
Score: 0.012
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Genetic variation in PNPLA3 confers susceptibility to nonalcoholic fatty liver disease. Nat Genet. 2008 Dec; 40(12):1461-5.
Score: 0.012
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Variation in PCSK9, low LDL cholesterol, and risk of peripheral arterial disease. Atherosclerosis. 2009 Jan; 202(1):211-5.
Score: 0.012
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A near null variant of 12/15-LOX encoded by a novel SNP in ALOX15 and the risk of coronary artery disease. Atherosclerosis. 2008 May; 198(1):136-44.
Score: 0.012
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A common allele on chromosome 9 associated with coronary heart disease. Science. 2007 Jun 08; 316(5830):1488-91.
Score: 0.011
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Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes. Ciba Found Symp. 1987; 130:99-127.
Score: 0.011
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Bias of the contribution of single-locus effects to the variance of a quantitative trait. Am J Hum Genet. 1986 Jul; 39(1):137-44.
Score: 0.011
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Influence of lipoprotein lipase gene Ser447Stop and beta1-adrenergic receptor gene Arg389Gly polymorphisms and their interaction on obesity from childhood to adulthood: the Bogalusa Heart Study. Int J Obes (Lond). 2006 Aug; 30(8):1183-8.
Score: 0.010
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A statistical analysis of spot variation using the two-dimensional polyacrylamide gel electrophoresis. Comput Biomed Res. 1986 Feb; 19(1):90-102.
Score: 0.010
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Pleiotropic genetic effects contribute to the correlation between HDL cholesterol, triglycerides, and LDL particle size in hypertensive sibships. Am J Hypertens. 2005 Jan; 18(1):99-103.
Score: 0.009
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APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study. J Lipid Res. 2005 Mar; 46(3):564-71.
Score: 0.009
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Interaction effect of Serine447Stop variant of the lipoprotein lipase gene and C-514T variant of the hepatic lipase gene on serum triglyceride levels in young adults: the Bogalusa Heart Study. Metabolism. 2003 Oct; 52(10):1337-42.
Score: 0.009
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Pro12Ala of the peroxisome proliferator-activated receptor-gamma2 gene is associated with lower serum insulin levels in nonobese African Americans: the Atherosclerosis Risk in Communities Study. Diabetes. 2003 Jun; 52(6):1568-72.
Score: 0.008
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Influence of lipoprotein lipase serine 447 stop polymorphism on tracking of triglycerides and HDL cholesterol from childhood to adulthood and familial risk of coronary artery disease: the Bogalusa heart study. Atherosclerosis. 2001 Dec; 159(2):367-73.
Score: 0.008
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Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease. Arterioscler Thromb Vasc Biol. 2001 Jun; 21(6):971-8.
Score: 0.007
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Sequence variation within the neuropeptide Y gene and obesity in Mexican Americans. Obes Res. 2000 May; 8(3):219-26.
Score: 0.007
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Recombinational and mutational hotspots within the human lipoprotein lipase gene. Am J Hum Genet. 2000 Jan; 66(1):69-83.
Score: 0.007
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Variants of the insulin receptor substrate-1 and fatty acid binding protein 2 genes and the risk of type 2 diabetes, obesity, and hyperinsulinemia in African-Americans: the Atherosclerosis Risk in Communities Study. Diabetes. 1999 Sep; 48(9):1868-72.
Score: 0.007
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Dietary intake and gene variation influence the response of plasma lipids to dietary intervention. Genet Epidemiol. 1992; 9(4):249-60.
Score: 0.004
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Frequency and effects of the apolipoprotein A-IV polymorphism. Clin Genet. 1990 Jun; 37(6):435-41.
Score: 0.003
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Genetics of primary hypertension. Clin Exp Hypertens A. 1986; 8(4-5):623-51.
Score: 0.003
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Studies of enzyme polymorphism in the Kamuela population of Drosophila mercatorum. III. Effects of variation at the alpha GPD locus and subflight stress on the energy charge and glycolytic intermediate concentrations. Genetics. 1983 Aug; 104(4):661-75.
Score: 0.002