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ROBERT J SCHWARTZ

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
DivisionMolecular & Cellular Biology
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    R01NS015050     (SCHWARTZ, ROBERT)Jan 1, 1979 - Dec 31, 1986
    NIH/NINDS
    DIFFERENTIATION OF ACTION IN MYOGENESIS
    Role: Principal Investigator

    D15PE012062     (SCHWARTZ, ROBERT)Jul 1, 1980 - Jun 30, 1993
    HRSA/BHP
    GRANTS FOR GRADUATE TRAINING IN FAMILY MEDICINE
    Role: Principal Investigator

    R01HL038401     (SCHWARTZ, ROBERT)Jan 8, 1987 - Dec 31, 1991
    NIH/NHLBI
    DIFFERENTIATION OF ACTIN MYOGENESIS
    Role: Principal Investigator

    R01HL045476     (SCHWARTZ, ROBERT)Jul 1, 1990 - Apr 30, 1995
    NIH/NHLBI
    REGULATION OF EMBRYONIC HEART DEVELOPMENT
    Role: Principal Investigator

    D32PE010012     (SCHWARTZ, ROBERT)Sep 1, 1992 - Aug 31, 1998
    HRSA/BHP
    DEPARTMENT OF FAMILY MEDICINE
    Role: Principal Investigator

    P01HL049953     (SCHWARTZ, ROBERT JOEL)May 20, 1993 - May 31, 2009
    NIH/NHLBI
    GENETIC APPROACHES TO EARLY CARDIAC DEVELOPMENT
    Role: Principal Investigator

    R01HL053982     (SCHWARTZ, ROBERT)May 1, 1995 - Apr 30, 1999
    NIH/NHLBI
    HORMONAL REGULATION OF CARDIAC GROWTH AND HYPERTROPHY
    Role: Principal Investigator

    R01HL064356     (SCHWARTZ, ROBERT JOEL)Feb 4, 2000 - Jan 31, 2004
    NIH/NHLBI
    RHOA KINASES IN CARDIAC HYPERTROPHY
    Role: Principal Investigator

    R01HL079628     (SCHWARTZ, ROBERT JOEL)Jan 15, 2005 - Dec 31, 2008
    NIH/NHLBI
    Cardiogenic Gene Switch, Role of SRF Phosphorylation
    Role: Principal Investigator

    R01HL089902     (SCHWARTZ, ROBERT JOEL)Apr 1, 2009 - Mar 31, 2014
    NIH/NHLBI
    The Role of Cysteine Rich Protein2 Binding Protein in Cardiovascular Development
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Kim BJ, Zaveri HP, Jordan VK, Hernandez-Garcia A, Jacob DJ, Zamora DL, Yu W, Schwartz RJ, Scott DA. RERE deficiency leads to decreased expression of GATA4 and the development of ventricular septal defects. Dis Model Mech. 2018 08 28; 11(9). PMID: 30061196.
      View in: PubMed
    2. Raghunathan S, Reynolds CL, Schwartz RJ, Stewart MD, McConnell BK. C.B-17 SCID mice develop epicardial calcinosis with unaltered cardiac function. Fundam Clin Pharmacol. 2019 Feb; 33(1):25-30. PMID: 29959870.
      View in: PubMed
    3. Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y. Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 07 27; 293(30):11659-11673. PMID: 29891551.
      View in: PubMed
    4. Lin X, Yang X, Li Q, Ma Y, Cui S, He D, Lin X, Schwartz RJ, Chang J. Correction for Lin et al., "Protein Tyrosine Phosphatase-Like A Regulates Myoblast Proliferation and Differentiation through MyoG and the Cell Cycling Signaling Pathway". Mol Cell Biol. 2017 08 15; 37(16). PMID: 28754770.
      View in: PubMed
    5. Gregoire S, Li G, Sturzu AC, Schwartz RJ, Wu SM. YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State. Stem Cells. 2017 08; 35(8):1913-1923. PMID: 28580685.
      View in: PubMed
    6. Valenzuela N, Soibam B, Li L, Wang J, Byers LA, Liu Y, Schwartz RJ, Stewart MD. HIRA deficiency in muscle fibers causes hypertrophy and susceptibility to oxidative stress. J Cell Sci. 2017 Aug 01; 130(15):2551-2563. PMID: 28600325.
      View in: PubMed
    7. Mohamed MA, Islas JF, Schwartz RJ, Birla RK. Electrical Stimulation of Artificial Heart Muscle: A Look Into the Electrophysiologic and Genetic Implications. ASAIO J. 2017 May/Jun; 63(3):333-341. PMID: 28459744.
      View in: PubMed
    8. Ma Y, Li Q, Li A, Wei Y, Long P, Jiang X, Sun F, Weiskirchen R, Wu B, Liang C, Grötzinger J, Wei Y, Yu W, Mercola M, Huang Y, Wang J, Yu Y, Schwartz RJ. The CSRP2BP histone acetyltransferase drives smooth muscle gene expression. Nucleic Acids Res. 2017 04 07; 45(6):3046-3058. PMID: 27940555.
      View in: PubMed
    9. Liu Y, Chen L, Diaz AD, Benham A, Xu X, Wijaya CS, Fa'ak F, Luo W, Soibam B, Azares A, Yu W, Lyu Q, Stewart MD, Gunaratne P, Cooney A, McConnell BK, Schwartz RJ. Mesp1 Marked Cardiac Progenitor Cells Repair Infarcted Mouse Hearts. Sci Rep. 2016 08 19; 6:31457. PMID: 27538477.
      View in: PubMed
    10. Shen X, Soibam B, Benham A, Xu X, Chopra M, Peng X, Yu W, Bao W, Liang R, Azares A, Liu P, Gunaratne PH, Mercola M, Cooney AJ, Schwartz RJ, Liu Y. miR-322/-503 cluster is expressed in the earliest cardiac progenitor cells and drives cardiomyocyte specification. Proc Natl Acad Sci U S A. 2016 08 23; 113(34):9551-6. PMID: 27512039.
      View in: PubMed
    11. Liu Y, Mercola M, Schwartz RJ. The All-Chemical Approach: A Solution for Converting Fibroblasts Into Myocytes. Circ Res. 2016 08 05; 119(4):505-7. PMID: 27492839.
      View in: PubMed
    12. Nimura K, Yamamoto M, Takeichi M, Saga K, Takaoka K, Kawamura N, Nitta H, Nagano H, Ishino S, Tanaka T, Schwartz RJ, Aburatani H, Kaneda Y. Regulation of alternative polyadenylation by Nkx2-5 and Xrn2 during mouse heart development. Elife. 2016 06 22; 5. PMID: 27331609.
      View in: PubMed
    13. Li J, Miao L, Shieh D, Spiotto E, Li J, Zhou B, Paul A, Schwartz RJ, Firulli AB, Singer HA, Huang G, Wu M. Single-Cell Lineage Tracing Reveals that Oriented Cell Division Contributes to Trabecular Morphogenesis and Regional Specification. Cell Rep. 2016 Apr 05; 15(1):158-170. PMID: 27052172.
      View in: PubMed
    14. Ma Y, Wang J, Yu Y, Schwartz RJ. PKG-1a mediates GATA4 transcriptional activity. Cell Signal. 2016 Jun; 28(6):585-94. PMID: 26946174.
      View in: PubMed
    15. Valenzuela N, Fan Q, Fa'ak F, Soibam B, Nagandla H, Liu Y, Schwartz RJ, McConnell BK, Stewart MD. Cardiomyocyte-specific conditional knockout of the histone chaperone HIRA in mice results in hypertrophy, sarcolemmal damage and focal replacement fibrosis. Dis Model Mech. 2016 Mar; 9(3):335-45. PMID: 26935106.
      View in: PubMed
    16. Stewart MD, Lopez S, Nagandla H, Soibam B, Benham A, Nguyen J, Valenzuela N, Wu HJ, Burns AR, Rasmussen TL, Tucker HO, Schwartz RJ. Mouse myofibers lacking the SMYD1 methyltransferase are susceptible to atrophy, internalization of nuclei and myofibrillar disarray. Dis Model Mech. 2016 Mar; 9(3):347-59. PMID: 26935107.
      View in: PubMed
    17. Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD. Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 01; 410(1):86-97. PMID: 26688546.
      View in: PubMed
    18. Soibam B, Benham A, Kim J, Weng KC, Yang L, Xu X, Robertson M, Azares A, Cooney AJ, Schwartz RJ, Liu Y. Genome-Wide Identification of MESP1 Targets Demonstrates Primary Regulation Over Mesendoderm Gene Activity. Stem Cells. 2015 Nov; 33(11):3254-65. PMID: 26205879.
      View in: PubMed
    19. Rasmussen TL, Ma Y, Park CY, Harriss J, Pierce SA, Dekker JD, Valenzuela N, Srivastava D, Schwartz RJ, Stewart MD, Tucker HO. Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses. PLoS One. 2015; 10(3):e0121765. PMID: 25803368.
      View in: PubMed
    20. Simmons O, Snider P, Wang J, Schwartz RJ, Chen Y, Conway SJ. Persistent Noggin arrests cardiomyocyte morphogenesis and results in early in utero lethality. Dev Dyn. 2015 Mar; 244(3):457-67. PMID: 25428115.
      View in: PubMed
    21. Nolte MJ, Wang Y, Deng JM, Swinton PG, Wei C, Guindani M, Schwartz RJ, Behringer RR. Functional analysis of limb transcriptional enhancers in the mouse. Evol Dev. 2014 Jul-Aug; 16(4):207-23. PMID: 24920384.
      View in: PubMed
    22. Liu Y, Kaneda R, Leja TW, Subkhankulova T, Tolmachov O, Minchiotti G, Schwartz RJ, Barahona M, Schneider MD. Hhex and Cer1 mediate the Sox17 pathway for cardiac mesoderm formation in embryonic stem cells. Stem Cells. 2014 Jun; 32(6):1515-26. PMID: 24585688.
      View in: PubMed
    23. Reineke EL, Benham A, Soibam B, Stashi E, Taegtmeyer H, Entman ML, Schwartz RJ, O'Malley BW. Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function. J Biol Chem. 2014 Jun 20; 289(25):17721-31. PMID: 24811170.
      View in: PubMed
    24. Zhao C, Guo H, Li J, Myint T, Pittman W, Yang L, Zhong W, Schwartz RJ, Schwarz JJ, Singer HA, Tallquist MD, Wu M. Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation. Development. 2014 Jan; 141(2):281-95. PMID: 24335256.
      View in: PubMed
    25. Craft JW, Zhang H, Charendoff MN, Mindrebo JT, Schwartz RJ, Briggs JM. Associations between the Rho kinase-1 catalytic and PH domain regulatory unit. J Mol Graph Model. 2013 Nov; 46:74-82. PMID: 24149321.
      View in: PubMed
    26. Zheng G, Tao Y, Yu W, Schwartz RJ. Brief report: SRF-dependent MiR-210 silences the sonic hedgehog signaling during cardiopoesis. Stem Cells. 2013 Oct; 31(10):2279-85. PMID: 23818299.
      View in: PubMed
    27. Wang J, Bai Y, Li H, Greene SB, Klysik E, Yu W, Schwartz RJ, Williams TJ, Martin JF. MicroRNA-17-92, a direct Ap-2a transcriptional target, modulates T-box factor activity in orofacial clefting. PLoS Genet. 2013; 9(9):e1003785. PMID: 24068957.
      View in: PubMed
    28. Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X. Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. Dev Biol. 2013 Nov 15; 383(2):239-52. PMID: 24056078.
      View in: PubMed
    29. Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T. Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec; 130(11-12):519-31. PMID: 23892084.
      View in: PubMed
    30. Tian X, Hu T, Zhang H, He L, Huang X, Liu Q, Yu W, He L, Yang Z, Zhang Z, Zhong TP, Yang X, Yang Z, Yan Y, Baldini A, Sun Y, Lu J, Schwartz RJ, Evans SM, Gittenberger-de Groot AC, Red-Horse K, Zhou B. Subepicardial endothelial cells invade the embryonic ventricle wall to form coronary arteries. Cell Res. 2013 Sep; 23(9):1075-90. PMID: 23797856.
      View in: PubMed
    31. Li Y, Yu W, Cooney AJ, Schwartz RJ, Liu Y. Brief report: Oct4 and canonical Wnt signaling regulate the cardiac lineage factor Mesp1 through a Tcf/Lef-Oct4 composite element. Stem Cells. 2013 Jun; 31(6):1213-7. PMID: 23417899.
      View in: PubMed
    32. Chen H, Zhang W, Sun X, Yoshimoto M, Chen Z, Zhu W, Liu J, Shen Y, Yong W, Li D, Zhang J, Lin Y, Li B, VanDusen NJ, Snider P, Schwartz RJ, Conway SJ, Field LJ, Yoder MC, Firulli AB, Carlesso N, Towbin JA, Shou W. Fkbp1a controls ventricular myocardium trabeculation and compaction by regulating endocardial Notch1 activity. Development. 2013 May; 140(9):1946-57. PMID: 23571217.
      View in: PubMed
    33. Liu Y, Schwartz RJ. Transient Mesp1 expression: a driver of cardiac cell fate determination. Transcription. 2013 May-Jun; 4(3):92-6. PMID: 23584093.
      View in: PubMed
    34. Nakano H, Liu X, Arshi A, Nakashima Y, van Handel B, Sasidharan R, Harmon AW, Shin JH, Schwartz RJ, Conway SJ, Harvey RP, Pashmforoush M, Mikkola HK, Nakano A. Haemogenic endocardium contributes to transient definitive haematopoiesis. Nat Commun. 2013; 4:1564. PMID: 23463007.
      View in: PubMed
    35. Tomasek JJ, Haaksma CJ, Schwartz RJ, Howard EW. Whole animal knockout of smooth muscle alpha-actin does not alter excisional wound healing or the fibroblast-to-myofibroblast transition. Wound Repair Regen. 2013 Jan-Feb; 21(1):166-76. PMID: 23253249.
      View in: PubMed
    36. Yoshioka K, Yoshida K, Cui H, Wakayama T, Takuwa N, Okamoto Y, Du W, Qi X, Asanuma K, Sugihara K, Aki S, Miyazawa H, Biswas K, Nagakura C, Ueno M, Iseki S, Schwartz RJ, Okamoto H, Sasaki T, Matsui O, Asano M, Adams RH, Takakura N, Takuwa Y. Endothelial PI3K-C2a, a class II PI3K, has an essential role in angiogenesis and vascular barrier function. Nat Med. 2012 Oct; 18(10):1560-9. PMID: 22983395.
      View in: PubMed
    37. Liu Y, Schwartz RJ. Reprogrammed cardiac fibroblasts to the rescue of heart failure. Circ Res. 2012 Sep 14; 111(7):831-2. PMID: 22982872.
      View in: PubMed
    38. Stewart MD, Deng JM, Stewart CA, Mullen RD, Wang Y, Lopez S, Serna MK, Huang CC, Janovick JA, Pask AJ, Schwartz RJ, Conn PM, Behringer RR. Mice harboring Gnrhr E90K, a mutation that causes protein misfolding and hypogonadotropic hypogonadism in humans, exhibit testis size reduction and ovulation failure. Mol Endocrinol. 2012 Nov; 26(11):1847-56. PMID: 22918878.
      View in: PubMed
    39. Islas JF, Liu Y, Weng KC, Robertson MJ, Zhang S, Prejusa A, Harger J, Tikhomirova D, Chopra M, Iyer D, Mercola M, Oshima RG, Willerson JT, Potaman VN, Schwartz RJ. Transcription factors ETS2 and MESP1 transdifferentiate human dermal fibroblasts into cardiac progenitors. Proc Natl Acad Sci U S A. 2012 Aug 07; 109(32):13016-21. PMID: 22826236.
      View in: PubMed
    40. Risebro CA, Petchey LK, Smart N, Gomes J, Clark J, Vieira JM, Yanni J, Dobrzynski H, Davidson S, Zuberi Z, Tinker A, Shui B, Tallini YI, Kotlikoff MI, Miquerol L, Schwartz RJ, Riley PR. Epistatic rescue of Nkx2.5 adult cardiac conduction disease phenotypes by prospero-related homeobox protein 1 and HDAC3. Circ Res. 2012 Jul 06; 111(2):e19-31. PMID: 22647876.
      View in: PubMed
    41. MacDonald ST, Bamforth SD, Bragança J, Chen CM, Broadbent C, Schneider JE, Schwartz RJ, Bhattacharya S. A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development. Eur Heart J. 2013 Aug; 34(32):2557-65. PMID: 22504313.
      View in: PubMed
    42. Zhou CC, Chang J, Mi T, Abbasi S, Gu D, Huang L, Zhang W, Kellems RE, Schwartz RJ, Xia Y. Targeted expression of Cre recombinase provokes placental-specific DNA recombination in transgenic mice. PLoS One. 2012; 7(2):e29236. PMID: 22363401.
      View in: PubMed
    43. Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J. Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012; 7(2):e31005. PMID: 22312437.
      View in: PubMed
    44. Yang X, Li Q, Lin X, Ma Y, Yue X, Tao Z, Wang F, Mckeehan WL, Wei L, Schwartz RJ, Chang J. Mechanism of fibrotic cardiomyopathy in mice expressing truncated Rho-associated coiled-coil protein kinase 1. FASEB J. 2012 May; 26(5):2105-16. PMID: 22278938.
      View in: PubMed
    45. Schwartz RJ, Yeh ET. Weighing in on heart failure: the role of SERCA2a SUMOylation. Circ Res. 2012 Jan 20; 110(2):198-9. PMID: 22267837.
      View in: PubMed
    46. Shardonofsky FR, Moore J, Schwartz RJ, Boriek AM. Airways in smooth muscle a-actin null mice experience a compensatory mechanism that modulates their contractile response. J Appl Physiol (1985). 2012 Mar; 112(5):898-903. PMID: 22134689.
      View in: PubMed
    47. Lin X, Yang X, Li Q, Ma Y, Cui S, He D, Lin X, Schwartz RJ, Chang J. Protein tyrosine phosphatase-like A regulates myoblast proliferation and differentiation through MyoG and the cell cycling signaling pathway. Mol Cell Biol. 2012 Jan; 32(2):297-308. PMID: 22106411.
      View in: PubMed
    48. Xin M, Kim Y, Sutherland LB, Qi X, McAnally J, Schwartz RJ, Richardson JA, Bassel-Duby R, Olson EN. Regulation of insulin-like growth factor signaling by Yap governs cardiomyocyte proliferation and embryonic heart size. Sci Signal. 2011 Oct 25; 4(196):ra70. PMID: 22028467.
      View in: PubMed
    49. Olaopa M, Zhou HM, Snider P, Wang J, Schwartz RJ, Moon AM, Conway SJ. Pax3 is essential for normal cardiac neural crest morphogenesis but is not required during migration nor outflow tract septation. Dev Biol. 2011 Aug 15; 356(2):308-22. PMID: 21600894.
      View in: PubMed
    50. Wang J, Chen L, Wen S, Zhu H, Yu W, Moskowitz IP, Shaw GM, Finnell RH, Schwartz RJ. Defective sumoylation pathway directs congenital heart disease. Birth Defects Res A Clin Mol Teratol. 2011 Jun; 91(6):468-76. PMID: 21563299.
      View in: PubMed
    51. Haaksma CJ, Schwartz RJ, Tomasek JJ. Myoepithelial cell contraction and milk ejection are impaired in mammary glands of mice lacking smooth muscle alpha-actin. Biol Reprod. 2011 Jul; 85(1):13-21. PMID: 21368298.
      View in: PubMed
    52. Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W. Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan; 138(2):303-15. PMID: 21177343.
      View in: PubMed
    53. Zhang J, Chang JY, Huang Y, Lin X, Luo Y, Schwartz RJ, Martin JF, Wang F. The FGF-BMP signaling axis regulates outflow tract valve primordium formation by promoting cushion neural crest cell differentiation. Circ Res. 2010 Nov 12; 107(10):1209-19. PMID: 20847311.
      View in: PubMed
    54. Hidaka K, Nitta T, Sugawa R, Shirai M, Schwartz RJ, Amagai T, Nitta S, Takahama Y, Morisaki T. Differentiation of pharyngeal endoderm from mouse embryonic stem cell. Stem Cells Dev. 2010 Nov; 19(11):1735-43. PMID: 20230268.
      View in: PubMed
    55. Patrick DM, Zhang CC, Tao Y, Yao H, Qi X, Schwartz RJ, Jun-Shen Huang L, Olson EN. Defective erythroid differentiation in miR-451 mutant mice mediated by 14-3-3zeta. Genes Dev. 2010 Aug 01; 24(15):1614-9. PMID: 20679397.
      View in: PubMed
    56. Wang J, Schwartz RJ. Sumoylation and regulation of cardiac gene expression. Circ Res. 2010 Jul 09; 107(1):19-29. PMID: 20616338.
      View in: PubMed
    57. Kang X, Qi Y, Zuo Y, Wang Q, Zou Y, Schwartz RJ, Cheng J, Yeh ET. SUMO-specific protease 2 is essential for suppression of polycomb group protein-mediated gene silencing during embryonic development. Mol Cell. 2010 Apr 23; 38(2):191-201. PMID: 20417598.
      View in: PubMed
    58. Tian Y, Yuan L, Goss AM, Wang T, Yang J, Lepore JJ, Zhou D, Schwartz RJ, Patel V, Cohen ED, Morrisey EE. Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development. Dev Cell. 2010 Feb 16; 18(2):275-87. PMID: 20159597.
      View in: PubMed
    59. Li D, Niu Z, Yu W, Qian Y, Wang Q, Li Q, Yi Z, Luo J, Wu X, Wang Y, Schwartz RJ, Liu M. SMYD1, the myogenic activator, is a direct target of serum response factor and myogenin. Nucleic Acids Res. 2009 Nov; 37(21):7059-71. PMID: 19783823.
      View in: PubMed
    60. Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T. T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. Proc Natl Acad Sci U S A. 2009 Nov 03; 106(44):18604-9. PMID: 19846762.
      View in: PubMed
    61. Nimura K, Ura K, Shiratori H, Ikawa M, Okabe M, Schwartz RJ, Kaneda Y. A histone H3 lysine 36 trimethyltransferase links Nkx2-5 to Wolf-Hirschhorn syndrome. Nature. 2009 Jul 09; 460(7252):287-91. PMID: 19483677.
      View in: PubMed
    62. Haudek SB, Gupta D, Dewald O, Schwartz RJ, Wei L, Trial J, Entman ML. Rho kinase-1 mediates cardiac fibrosis by regulating fibroblast precursor cell differentiation. Cardiovasc Res. 2009 Aug 01; 83(3):511-8. PMID: 19406912.
      View in: PubMed
    63. Que J, Luo X, Schwartz RJ, Hogan BL. Multiple roles for Sox2 in the developing and adult mouse trachea. Development. 2009 Jun; 136(11):1899-907. PMID: 19403656.
      View in: PubMed
    64. DiMichele LA, Hakim ZS, Sayers RL, Rojas M, Schwartz RJ, Mack CP, Taylor JM. Transient expression of FRNK reveals stage-specific requirement for focal adhesion kinase activity in cardiac growth. Circ Res. 2009 May 22; 104(10):1201-8. PMID: 19372463.
      View in: PubMed
    65. Lombardi R, Dong J, Rodriguez G, Bell A, Leung TK, Schwartz RJ, Willerson JT, Brugada R, Marian AJ. Genetic fate mapping identifies second heart field progenitor cells as a source of adipocytes in arrhythmogenic right ventricular cardiomyopathy. Circ Res. 2009 May 08; 104(9):1076-84. PMID: 19359597.
      View in: PubMed
    66. Verzi MP, Stanfel MN, Moses KA, Kim BM, Zhang Y, Schwartz RJ, Shivdasani RA, Zimmer WE. Role of the homeodomain transcription factor Bapx1 in mouse distal stomach development. Gastroenterology. 2009 May; 136(5):1701-10. PMID: 19208343.
      View in: PubMed
    67. Risebro CA, Searles RG, Melville AA, Ehler E, Jina N, Shah S, Pallas J, Hubank M, Dillard M, Harvey NL, Schwartz RJ, Chien KR, Oliver G, Riley PR. Prox1 maintains muscle structure and growth in the developing heart. Development. 2009 Feb; 136(3):495-505. PMID: 19091769.
      View in: PubMed
    68. Niu Z, Iyer D, Conway SJ, Martin JF, Ivey K, Srivastava D, Nordheim A, Schwartz RJ. Serum response factor orchestrates nascent sarcomerogenesis and silences the biomineralization gene program in the heart. Proc Natl Acad Sci U S A. 2008 Nov 18; 105(46):17824-9. PMID: 19004760.
      View in: PubMed
    69. Zhang J, Lin Y, Zhang Y, Lan Y, Lin C, Moon AM, Schwartz RJ, Martin JF, Wang F. Frs2alpha-deficiency in cardiac progenitors disrupts a subset of FGF signals required for outflow tract morphogenesis. Development. 2008 Nov; 135(21):3611-22. PMID: 18832393.
      View in: PubMed
    70. Wang J, Zhang H, Iyer D, Feng XH, Schwartz RJ. Regulation of cardiac specific nkx2.5 gene activity by small ubiquitin-like modifier. J Biol Chem. 2008 Aug 22; 283(34):23235-43. PMID: 18579533.
      View in: PubMed
    71. Ivey KN, Muth A, Arnold J, King FW, Yeh RF, Fish JE, Hsiao EC, Schwartz RJ, Conklin BR, Bernstein HS, Srivastava D. MicroRNA regulation of cell lineages in mouse and human embryonic stem cells. Cell Stem Cell. 2008 Mar 06; 2(3):219-29. PMID: 18371447.
      View in: PubMed
    72. Niu Z, Li A, Zhang SX, Schwartz RJ. Serum response factor micromanaging cardiogenesis. Curr Opin Cell Biol. 2007 Dec; 19(6):618-27. PMID: 18023168.
      View in: PubMed
    73. Zhu H, Cabrera RM, Wlodarczyk BJ, Bozinov D, Wang D, Schwartz RJ, Finnell RH. Differentially expressed genes in embryonic cardiac tissues of mice lacking Folr1 gene activity. BMC Dev Biol. 2007 Nov 20; 7:128. PMID: 18028541.
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    74. Hakim ZS, DiMichele LA, Doherty JT, Homeister JW, Beggs HE, Reichardt LF, Schwartz RJ, Brackhan J, Smithies O, Mack CP, Taylor JM. Conditional deletion of focal adhesion kinase leads to defects in ventricular septation and outflow tract alignment. Mol Cell Biol. 2007 Aug; 27(15):5352-64. PMID: 17526730.
      View in: PubMed
    75. Smart N, Risebro CA, Melville AA, Moses K, Schwartz RJ, Chien KR, Riley PR. Thymosin beta-4 is essential for coronary vessel development and promotes neovascularization via adult epicardium. Ann N Y Acad Sci. 2007 Sep; 1112:171-88. PMID: 17495252.
      View in: PubMed
    76. Zhu L, Harutyunyan KG, Peng JL, Wang J, Schwartz RJ, Belmont JW. Identification of a novel role of ZIC3 in regulating cardiac development. Hum Mol Genet. 2007 Jul 15; 16(14):1649-60. PMID: 17468179.
      View in: PubMed
    77. Shah VR, Koster MI, Roop DR, Spencer DM, Wei L, Li Q, Schwartz RJ, Chang J. Double-inducible gene activation system for caspase 3 and 9 in epidermis. Genesis. 2007 Apr; 45(4):194-9. PMID: 17417788.
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    78. Zhu H, Wlodarczyk BJ, Scott M, Yu W, Merriweather M, Gelineau-van Waes J, Schwartz RJ, Finnell RH. Cardiovascular abnormalities in Folr1 knockout mice and folate rescue. Birth Defects Res A Clin Mol Teratol. 2007 Apr; 79(4):257-68. PMID: 17286298.
      View in: PubMed
    79. Zhao Y, Ransom JF, Li A, Vedantham V, von Drehle M, Muth AN, Tsuchihashi T, McManus MT, Schwartz RJ, Srivastava D. Dysregulation of cardiogenesis, cardiac conduction, and cell cycle in mice lacking miRNA-1-2. Cell. 2007 Apr 20; 129(2):303-17. PMID: 17397913.
      View in: PubMed
    80. Liu Y, Asakura M, Inoue H, Nakamura T, Sano M, Niu Z, Chen M, Schwartz RJ, Schneider MD. Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells. Proc Natl Acad Sci U S A. 2007 Mar 06; 104(10):3859-64. PMID: 17360443.
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    88. Ilagan R, Abu-Issa R, Brown D, Yang YP, Jiao K, Schwartz RJ, Klingensmith J, Meyers EN. Fgf8 is required for anterior heart field development. Development. 2006 Jun; 133(12):2435-45. PMID: 16720880.
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    92. Iyer D, Chang D, Marx J, Wei L, Olson EN, Parmacek MS, Balasubramanyam A, Schwartz RJ. Serum response factor MADS box serine-162 phosphorylation switches proliferation and myogenic gene programs. Proc Natl Acad Sci U S A. 2006 Mar 21; 103(12):4516-21. PMID: 16537394.
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    93. Oka T, Maillet M, Watt AJ, Schwartz RJ, Aronow BJ, Duncan SA, Molkentin JD. Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability. Circ Res. 2006 Mar 31; 98(6):837-45. PMID: 16514068.
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    97. Liu W, Selever J, Murali D, Sun X, Brugger SM, Ma L, Schwartz RJ, Maxson R, Furuta Y, Martin JF. Threshold-specific requirements for Bmp4 in mandibular development. Dev Biol. 2005 Jul 15; 283(2):282-93. PMID: 15936012.
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    98. Niu Z, Yu W, Zhang SX, Barron M, Belaguli NS, Schneider MD, Parmacek M, Nordheim A, Schwartz RJ. Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets. J Biol Chem. 2005 Sep 16; 280(37):32531-8. PMID: 15929941.
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    100. Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, DeMayo FJ, Tsai MJ, Tsai SY. COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May; 132(9):2179-89. PMID: 15829524.
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    102. Vlahopoulos S, Zimmer WE, Jenster G, Belaguli NS, Balk SP, Brinkmann AO, Lanz RB, Zoumpourlis VC, Schwartz RJ. Recruitment of the androgen receptor via serum response factor facilitates expression of a myogenic gene. J Biol Chem. 2005 Mar 04; 280(9):7786-92. PMID: 15623502.
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    103. Barron MR, Belaguli NS, Zhang SX, Trinh M, Iyer D, Merlo X, Lough JW, Parmacek MS, Bruneau BG, Schwartz RJ. Serum response factor, an enriched cardiac mesoderm obligatory factor, is a downstream gene target for Tbx genes. J Biol Chem. 2005 Mar 25; 280(12):11816-28. PMID: 15591049.
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    104. Zimmerman RA, Tomasek JJ, McRae J, Haaksma CJ, Schwartz RJ, Lin HK, Cowan RL, Jones AN, Kropp BP. Decreased expression of smooth muscle alpha-actin results in decreased contractile function of the mouse bladder. J Urol. 2004 Oct; 172(4 Pt 2):1667-72. PMID: 15371786.
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    105. Wang J, Feng XH, Schwartz RJ. SUMO-1 modification activated GATA4-dependent cardiogenic gene activity. J Biol Chem. 2004 Nov 19; 279(47):49091-8. PMID: 15337742.
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    106. Xu H, Morishima M, Wylie JN, Schwartz RJ, Bruneau BG, Lindsay EA, Baldini A. Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract. Development. 2004 Jul; 131(13):3217-27. PMID: 15175244.
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    107. Brunelli S, Tagliafico E, De Angelis FG, Tonlorenzi R, Baesso S, Ferrari S, Niinobe M, Yoshikawa K, Schwartz RJ, Bozzoni I, Ferrari S, Cossu G. Msx2 and necdin combined activities are required for smooth muscle differentiation in mesoangioblast stem cells. Circ Res. 2004 Jun 25; 94(12):1571-8. PMID: 15155529.
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    108. Pursel VG, Mitchell AD, Bee G, Elsasser TH, McMurtry JP, Wall RJ, Coleman ME, Schwartz RJ. Growth and tissue accretion rates of swine expressing an insulin-like growth factor I transgene. Anim Biotechnol. 2004 May; 15(1):33-45. PMID: 15248599.
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    109. Oh H, Chi X, Bradfute SB, Mishina Y, Pocius J, Michael LH, Behringer RR, Schwartz RJ, Entman ML, Schneider MD. Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Ann N Y Acad Sci. 2004 May; 1015:182-9. PMID: 15201159.
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    111. Wei L, Taffet GE, Khoury DS, Bo J, Li Y, Yatani A, Delaughter MC, Klevitsky R, Hewett TE, Robbins J, Michael LH, Schneider MD, Entman ML, Schwartz RJ. Disruption of Rho signaling results in progressive atrioventricular conduction defects while ventricular function remains preserved. FASEB J. 2004 May; 18(7):857-9. PMID: 15033930.
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    113. Tetzlaff MT, Yu W, Li M, Zhang P, Finegold M, Mahon K, Harper JW, Schwartz RJ, Elledge SJ. Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein. Proc Natl Acad Sci U S A. 2004 Mar 09; 101(10):3338-45. PMID: 14766969.
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    114. Brown CO, Chi X, Garcia-Gras E, Shirai M, Feng XH, Schwartz RJ. The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem. 2004 Mar 12; 279(11):10659-69. PMID: 14662776.
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    115. Mohapatra B, Jimenez S, Lin JH, Bowles KR, Coveler KJ, Marx JG, Chrisco MA, Murphy RT, Lurie PR, Schwartz RJ, Elliott PM, Vatta M, McKenna W, Towbin JA, Bowles NE. Mutations in the muscle LIM protein and alpha-actinin-2 genes in dilated cardiomyopathy and endocardial fibroelastosis. Mol Genet Metab. 2003 Sep-Oct; 80(1-2):207-15. PMID: 14567970.
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    116. Chang J, Wei L, Otani T, Youker KA, Entman ML, Schwartz RJ. Inhibitory cardiac transcription factor, SRF-N, is generated by caspase 3 cleavage in human heart failure and attenuated by ventricular unloading. Circulation. 2003 Jul 29; 108(4):407-13. PMID: 12874181.
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    117. Iyer D, Belaguli N, Flück M, Rowan BG, Wei L, Weigel NL, Booth FW, Epstein HF, Schwartz RJ, Balasubramanyam A. Novel phosphorylation target in the serum response factor MADS box regulates alpha-actin transcription. Biochemistry. 2003 Jun 24; 42(24):7477-86. PMID: 12809504.
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    118. Chi X, Zhang SX, Yu W, DeMayo FJ, Rosenberg SM, Schwartz RJ. Expression of Nkx2-5-GFP bacterial artificial chromosome transgenic mice closely resembles endogenous Nkx2-5 gene activity. Genesis. 2003 Apr; 35(4):220-6. PMID: 12717733.
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    119. Davis FJ, Gupta M, Camoretti-Mercado B, Schwartz RJ, Gupta MP. Calcium/calmodulin-dependent protein kinase activates serum response factor transcription activity by its dissociation from histone deacetylase, HDAC4. Implications in cardiac muscle gene regulation during hypertrophy. J Biol Chem. 2003 May 30; 278(22):20047-58. PMID: 12663674.
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    120. Chang DF, Belaguli NS, Iyer D, Roberts WB, Wu SP, Dong XR, Marx JG, Moore MS, Beckerle MC, Majesky MW, Schwartz RJ. Cysteine-rich LIM-only proteins CRP1 and CRP2 are potent smooth muscle differentiation cofactors. Dev Cell. 2003 Jan; 4(1):107-18. PMID: 12530967.
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    121. Fiorotto ML, Schwartz RJ, Delaughter MC. Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. FASEB J. 2003 Jan; 17(1):59-60. PMID: 12528713.
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    122. Rabinovsky ED, Gelir E, Gelir S, Lui H, Kattash M, DeMayo FJ, Shenaq SM, Schwartz RJ. Targeted expression of IGF-1 transgene to skeletal muscle accelerates muscle and motor neuron regeneration. FASEB J. 2003 Jan; 17(1):53-5. PMID: 12424223.
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    123. Stringer JL, Belaguli NS, Iyer D, Schwartz RJ, Balasubramanyam A. Developmental expression of serum response factor in the rat central nervous system. Brain Res Dev Brain Res. 2002 Sep 20; 138(1):81-6. PMID: 12234660.
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    125. Khan AS, Fiorotto ML, Hill LA, Malone PB, Cummings KK, Parghi D, Schwartz RJ, Smith RG, Draghia-Akli R. Nonhereditary enhancement of progeny growth. Endocrinology. 2002 Sep; 143(9):3561-7. PMID: 12193571.
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    128. Draghia-Akli R, Malone PB, Hill LA, Ellis KM, Schwartz RJ, Nordstrom JL. Enhanced animal growth via ligand-regulated GHRH myogenic-injectable vectors. FASEB J. 2002 Mar; 16(3):426-8. PMID: 11790726.
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    132. Wei L, Roberts W, Wang L, Yamada M, Zhang S, Zhao Z, Rivkees SA, Schwartz RJ, Imanaka-Yoshida K. Rho kinases play an obligatory role in vertebrate embryonic organogenesis. Development. 2001 Aug; 128(15):2953-62. PMID: 11532918.
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    133. Li YP, Schwartz RJ. TNF-alpha regulates early differentiation of C2C12 myoblasts in an autocrine fashion. FASEB J. 2001 Jun; 15(8):1413-5. PMID: 11387241.
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    135. Moore ML, Wang GL, Belaguli NS, Schwartz RJ, McMillin JB. GATA-4 and serum response factor regulate transcription of the muscle-specific carnitine palmitoyltransferase I beta in rat heart. J Biol Chem. 2001 Jan 12; 276(2):1026-33. PMID: 11038368.
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    137. Schneider MD, Schwartz RJ. Chips ahoy: gene expression in failing hearts surveyed by high-density microarrays. Circulation. 2000 Dec 19; 102(25):3026-7. PMID: 11120689.
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    139. Yamada M, Revelli JP, Eichele G, Barron M, Schwartz RJ. Expression of chick Tbx-2, Tbx-3, and Tbx-5 genes during early heart development: evidence for BMP2 induction of Tbx2. Dev Biol. 2000 Dec 01; 228(1):95-105. PMID: 11087629.
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    148. Yamada M, Szendro PI, Prokscha A, Schwartz RJ, Eichele G. Evidence for a role of Smad6 in chick cardiac development. Dev Biol. 1999 Nov 01; 215(1):48-61. PMID: 10525349.
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    149. Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ. Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. FASEB J. 1999 Nov; 13(14):1923-9. PMID: 10544175.
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    150. Schwartz RJ, Olson EN. Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. Development. 1999 Oct; 126(19):4187-92. PMID: 10477287.
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    152. Flück M, Carson JA, Schwartz RJ, Booth FW. SRF protein is upregulated during stretch-induced hypertrophy of rooster ALD muscle. J Appl Physiol (1985). 1999 Jun; 86(6):1793-9. PMID: 10368339.
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    153. Landerholm TE, Dong XR, Lu J, Belaguli NS, Schwartz RJ, Majesky MW. A role for serum response factor in coronary smooth muscle differentiation from proepicardial cells. Development. 1999 May; 126(10):2053-62. PMID: 10207131.
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    154. Schneider MD, Schwartz RJ. Heart or hand? Unmasking the basis for specific Holt-Oram phenotypes. Proc Natl Acad Sci U S A. 1999 Mar 16; 96(6):2577-8. PMID: 10077549.
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    155. Li X, Eastman EM, Schwartz RJ, Draghia-Akli R. Synthetic muscle promoters: activities exceeding naturally occurring regulatory sequences. Nat Biotechnol. 1999 Mar; 17(3):241-5. PMID: 10096290.
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    158. Criswell DS, Booth FW, DeMayo F, Schwartz RJ, Gordon SE, Fiorotto ML. Overexpression of IGF-I in skeletal muscle of transgenic mice does not prevent unloading-induced atrophy. Am J Physiol. 1998 Sep; 275(3 Pt 1):E373-9. PMID: 9725801.
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    175. Chen CY, Croissant J, Majesky M, Topouzis S, McQuinn T, Frankovsky MJ, Schwartz RJ. Activation of the cardiac alpha-actin promoter depends upon serum response factor, Tinman homologue, Nkx-2.5, and intact serum response elements. Dev Genet. 1996; 19(2):119-30. PMID: 8900044.
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    176. Chen CY, Schwartz RJ. Identification of novel DNA binding targets and regulatory domains of a murine tinman homeodomain factor, nkx-2.5. J Biol Chem. 1995 Jun 30; 270(26):15628-33. PMID: 7797561.
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    177. Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem. 1995 May 19; 270(20):12109-16. PMID: 7744859.
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    178. Carson JA, Yan Z, Booth FW, Coleman ME, Schwartz RJ, Stump CS. Regulation of skeletal alpha-actin promoter in young chickens during hypertrophy caused by stretch overload. Am J Physiol. 1995 Apr; 268(4 Pt 1):C918-24. PMID: 7537453.
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    179. MacLellan WR, Lee TC, Schwartz RJ, Schneider MD. Transforming growth factor-beta response elements of the skeletal alpha-actin gene. Combinatorial action of serum response factor, YY1, and the SV40 enhancer-binding protein, TEF-1. J Biol Chem. 1994 Jun 17; 269(24):16754-60. PMID: 8206998.
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    180. Moss JB, McQuinn TC, Schwartz RJ. The avian cardiac alpha-actin promoter is regulated through a pair of complex elements composed of E boxes and serum response elements that bind both positive- and negative-acting factors. J Biol Chem. 1994 Apr 29; 269(17):12731-40. PMID: 8175685.
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    181. Lee TC, Zhang Y, Schwartz RJ. Bifunctional transcriptional properties of YY1 in regulating muscle actin and c-myc gene expression during myogenesis. Oncogene. 1994 Apr; 9(4):1047-52. PMID: 8134108.
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    182. Lee TC, Schwartz RJ. Novel use of a polymeric chromophore in detecting sequence-specific DNA-binding proteins. Biotechniques. 1993 Sep; 15(3):390, 393. PMID: 8217147.
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    183. Sands AT, Hansen TN, Demayo FJ, Stanley LA, Xin L, Schwartz RJ. Cytoplasmic beta-actin promoter produces germ cell and preimplantation embryonic transgene expression. Mol Reprod Dev. 1993 Feb; 34(2):117-26. PMID: 8442950.
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    184. Lee TC, Shi Y, Schwartz RJ. Displacement of BrdUrd-induced YY1 by serum response factor activates skeletal alpha-actin transcription in embryonic myoblasts. Proc Natl Acad Sci U S A. 1992 Oct 15; 89(20):9814-8. PMID: 1409704.
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    185. Lee TC, Schwartz RJ. Using proteases to avoid false identification of DNA-protein complexes in gel shift assays. Biotechniques. 1992 Apr; 12(4):486-90. PMID: 1503744.
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    186. Parker TG, Chow KL, Schwartz RJ, Schneider MD. Positive and negative control of the skeletal alpha-actin promoter in cardiac muscle. A proximal serum response element is sufficient for induction by basic fibroblast growth factor (FGF) but not for inhibition by acidic FGF. J Biol Chem. 1992 Feb 15; 267(5):3343-50. PMID: 1371118.
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    187. Blank RS, McQuinn TC, Yin KC, Thompson MM, Takeyasu K, Schwartz RJ, Owens GK. Elements of the smooth muscle alpha-actin promoter required in cis for transcriptional activation in smooth muscle. Evidence for cell type-specific regulation. J Biol Chem. 1992 Jan 15; 267(2):984-9. PMID: 1730687.
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    188. Lee TC, Schwartz RJ. Differential detection of multiple DNA-binding complexes using dissimilar polyanion competitors. Nucleic Acids Res. 1992 Jan 11; 20(1):140. PMID: 1738593.
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    189. Black FM, Packer SE, Parker TG, Michael LH, Roberts R, Schwartz RJ, Schneider MD. The vascular smooth muscle alpha-actin gene is reactivated during cardiac hypertrophy provoked by load. J Clin Invest. 1991 Nov; 88(5):1581-8. PMID: 1834699.
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    190. Zhu YY, Schwartz RJ, Crow MT. Phorbol esters selectively downregulate contractile protein gene expression in terminally differentiated myotubes through transcriptional repression and message destabilization. J Cell Biol. 1991 Nov; 115(3):745-54. PMID: 1717491.
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    191. Lee TC, Chow KL, Fang P, Schwartz RJ. Activation of skeletal alpha-actin gene transcription: the cooperative formation of serum response factor-binding complexes over positive cis-acting promoter serum response elements displaces a negative-acting nuclear factor enriched in replicating myoblasts and nonmyogenic cells. Mol Cell Biol. 1991 Oct; 11(10):5090-100. PMID: 1922033.
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    192. French BA, Chow KL, Olson EN, Schwartz RJ. Heterodimers of myogenic helix-loop-helix regulatory factors and E12 bind a complex element governing myogenic induction of the avian cardiac alpha-actin promoter. Mol Cell Biol. 1991 May; 11(5):2439-50. PMID: 1850096.
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    193. Chow KL, Hogan ME, Schwartz RJ. Phased cis-acting promoter elements interact at short distances to direct avian skeletal alpha-actin gene transcription. Proc Natl Acad Sci U S A. 1991 Feb 15; 88(4):1301-5. PMID: 1996331.
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    194. Parker TG, Chow KL, Schwartz RJ, Schneider MD. TGF-beta 1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cells. Ciba Found Symp. 1991; 157:152-60; discussion 161-4. PMID: 1712696.
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    195. Sands AT, DeMayo F, Lei X, Schwartz RJ. Targeting of gene expression to skeletal and cardiac muscle of trangenic animals. SAAS Bull Biochem Biotechnol. 1991 Jan; 4:27-33. PMID: 1367249.
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    196. Parker TG, Chow KL, Schwartz RJ, Schneider MD. Differential regulation of skeletal alpha-actin transcription in cardiac muscle by two fibroblast growth factors. Proc Natl Acad Sci U S A. 1990 Sep; 87(18):7066-70. PMID: 2402491.
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    197. French BA, Bergsma DJ, Schwartz RJ. Analysis of a CR1 (chicken repeat) sequence flanking the 5' end of the gene encoding alpha-skeletal actin. Gene. 1990 Apr 16; 88(2):173-80. PMID: 2347492.
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    198. Chow KL, Schwartz RJ. A combination of closely associated positive and negative cis-acting promoter elements regulates transcription of the skeletal alpha-actin gene. Mol Cell Biol. 1990 Feb; 10(2):528-38. PMID: 2300053.
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    199. Chakraborty R, Schwartz RJ. Selective neutrality of surname, distribution in an immigrant indian community of Houston, Texas. Am J Hum Biol. 1990; 2(1):1-15. PMID: 28520260.
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    200. Ruzicka DL, Schwartz RJ. Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation. J Cell Biol. 1988 Dec; 107(6 Pt 2):2575-86. PMID: 3204121.
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    201. Hecht JT, Hood OJ, Schwartz RJ, Hennessey JC, Bernhardt BA, Horton WA. Obesity in achondroplasia. Am J Med Genet. 1988 Nov; 31(3):597-602. PMID: 3228140.
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    202. Grichnik JM, French BA, Schwartz RJ. The chicken skeletal alpha-actin gene promoter region exhibits partial dyad symmetry and a capacity to drive bidirectional transcription. Mol Cell Biol. 1988 Nov; 8(11):4587-97. PMID: 3211124.
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    203. Hayward LJ, Zhu YY, Schwartz RJ. Cellular localization of muscle and nonmuscle actin mRNAs in chicken primary myogenic cultures: the induction of alpha-skeletal actin mRNA is regulated independently of alpha-cardiac actin gene expression. J Cell Biol. 1988 Jun; 106(6):2077-86. PMID: 3384853.
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    204. DiLella AG, Hope DA, Chen H, Trumbauer M, Schwartz RJ, Smith RG. Utility of firefly luciferase as a reporter gene for promoter activity in transgenic mice. Nucleic Acids Res. 1988 May 11; 16(9):4159. PMID: 3375079.
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    205. Carroll SL, Bergsma DJ, Schwartz RJ. A 29-nucleotide DNA segment containing an evolutionarily conserved motif is required in cis for cell-type-restricted repression of the chicken alpha-smooth muscle actin gene core promoter. Mol Cell Biol. 1988 Jan; 8(1):241-50. PMID: 3336359.
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    206. Carroll SL, Bergsma DJ, Schwartz RJ. Structure and complete nucleotide sequence of the chicken alpha-smooth muscle (aortic) actin gene. An actin gene which produces multiple messenger RNAs. J Biol Chem. 1986 Jul 05; 261(19):8965-76. PMID: 3013870.
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    207. Bergsma DJ, Grichnik JM, Gossett LM, Schwartz RJ. Delimitation and characterization of cis-acting DNA sequences required for the regulated expression and transcriptional control of the chicken skeletal alpha-actin gene. Mol Cell Biol. 1986 Jul; 6(7):2462-75. PMID: 3785201.
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    208. Hayward LJ, Schwartz RJ. Sequential expression of chicken actin genes during myogenesis. J Cell Biol. 1986 Apr; 102(4):1485-93. PMID: 3007534.
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    209. Grichnik JM, Bergsma DJ, Schwartz RJ. Tissue restricted and stage specific transcription is maintained within 411 nucleotides flanking the 5' end of the chicken alpha-skeletal actin gene. Nucleic Acids Res. 1986 Feb 25; 14(4):1683-701. PMID: 3005979.
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    210. Bergsma DJ, Chang KS, Schwartz RJ. Novel chicken actin gene: third cytoplasmic isoform. Mol Cell Biol. 1985 May; 5(5):1151-62. PMID: 4000121.
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    211. Sen S, Siciliano MJ, Johnston DA, Schwartz RJ, Kuo T. The expression and chromatin structure of the chicken glyceraldehyde-3-phosphate dehydrogenase gene in mouse cells. J Biol Chem. 1985 Mar 10; 260(5):3071-8. PMID: 3972817.
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    212. Chang KS, Rothblum KN, Schwartz RJ. The complete sequence of the chicken alpha-cardiac actin gene: a highly conserved vertebrate gene. Nucleic Acids Res. 1985 Feb 25; 13(4):1223-37. PMID: 3855241.
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    213. Stone EM, Rothblum KN, Schwartz RJ. Intron-dependent evolution of chicken glyceraldehyde phosphate dehydrogenase gene. Nature. 1985 Feb 7-13; 313(6002):498-500. PMID: 3969156.
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    214. Chang KS, Zimmer WE, Bergsma DJ, Dodgson JB, Schwartz RJ. Isolation and characterization of six different chicken actin genes. Mol Cell Biol. 1984 Nov; 4(11):2498-508. PMID: 6513927.
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    215. Dugaiczyk A, Haron JA, Stone EM, Dennison OE, Rothblum KN, Schwartz RJ. Cloning and sequencing of a deoxyribonucleic acid copy of glyceraldehyde-3-phosphate dehydrogenase messenger ribonucleic acid isolated from chicken muscle. Biochemistry. 1983 Mar 29; 22(7):1605-13. PMID: 6303388.
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    216. Schwartz RJ, Stone EM. Cloning of contractile protein genes. Cell Muscle Motil. 1983; 3:195-257. PMID: 6200200.
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    217. Schwartz RJ. Recombinant DNA studies of muscle and nonmuscle actin genes. Anat Rec Suppl. 1983; 1:27-50. PMID: 6202172.
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    218. Schwartz RJ. Quantitation of actin mRNA content in muscle cell cultures. J Histochem Cytochem. 1981 Sep; 29(9):1014-20. PMID: 7288159.
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    219. Schwartz RJ, Rothblum KN. Gene switching in myogenesis: differential expression of the chicken actin multigene family. Biochemistry. 1981 Jul 07; 20(14):4122-9. PMID: 7284314.
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    220. Moss M, Schwartz R. Regulation of tropomyosin gene expression during myogenesis. Mol Cell Biol. 1981 Mar; 1(3):289-301. PMID: 6086009.
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    221. Schwartz RJ, Haron JA, Rothblum KN, Dugaiczyk A. Regulation of muscle differentiation: cloning of sequences from alpha-actin messenger ribonucleic acid. Biochemistry. 1980 Dec 09; 19(25):5883-90. PMID: 7006694.
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    222. Garber AJ, Schwartz RJ, Seidel CL, Silvers A, Entman ML. Skeletal muscle protein and amino acid metabolism in hereditary mouse muscular dystrophy. Accelerated protein turnover and increased alanine and glutamine formation and release. J Biol Chem. 1980 Sep 10; 255(17):8315-24. PMID: 6893325.
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    223. Schwartz RJ, Rothblum K. Regulation of muscle differentiation: isolation and purification of chick actin messenger ribonucleic acid and quantitation with complementary deoxyribonucleic acid probes. Biochemistry. 1980 May 27; 19(11):2506-14. PMID: 6892992.
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    224. Smith RG, Schwartz RJ. Isolation and purification of a hen nuclear oestrogen receptor and its effect on transcription of chick chromatin. Biochem J. 1979 Nov 15; 184(2):331-43. PMID: 534532.
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    225. Moss M, Norris JS, Peck EJ, Schwartz RJ. Alterations in iodinated cell surface proteins during myogenesis. Exp Cell Res. 1978 May; 113(2):445-50. PMID: 299655.
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    226. Schwartz RJ, Chang C, Schrader WT, O'Malley BW. Effect of progesterone receptors on transcription. Ann N Y Acad Sci. 1977 Mar 11; 286:147-60. PMID: 363019.
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    227. O'Malley BW, Towle HC, Schwartz RJ. Regulation of gene expression in eucaryotes. Annu Rev Genet. 1977; 11:239-75. PMID: 339816.
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    228. O'Malley BW, Coty WA, Schwartz RJ, Schrader WT. Effects of steroid hormone receptors on gene transcription. Adv Pathobiol. 1977; (6):79-96. PMID: 331918.
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    229. O'Malley BW, Schwartz RJ, Schrader WT. A review of regulation of gene expression by steroid hormone receptors. J Steroid Biochem. 1976 Nov-Dec; 7(11-12):1151-9. PMID: 1025362.
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    230. Buller RE, Schwartz RJ, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct. In vitro effect of receptor subunits on gene transcription. J Biol Chem. 1976 Sep 10; 251(17):5178-86. PMID: 182692.
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    231. Schwartz RJ, Kuhn RW, Buller RE, Schrader WT, O'Malley BW. Progesterone-binding components of chick oviduct. In vitro effects of purified hormone-receptor complexes on the initiation of RNA synthesis in chromatin. J Biol Chem. 1976 Sep 10; 251(17):5166-77. PMID: 182691.
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    232. Buller RE, Schwartz RJ, O'Malley BW. Steroid hormone receptor fraction stimulation of RNA synthesis: a caution. Biochem Biophys Res Commun. 1976 Mar 08; 69(1):106-13. PMID: 177017.
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    233. Harris SE, Schwartz RJ, Tsai MJ, O'Malley BW, Roy AK. Effect of estrogen on gene expression in the chick oviduct. In vitro transcription of the ovalbumin gene in chromatin. J Biol Chem. 1976 Jan 25; 251(2):524-9. PMID: 1245487.
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    234. Towle HC, Tsai MJ, Hirose M, Tsai SY, Schwartz RJ, Parker MG, O'Malley BW. Regulation of transcription of the eucaryotic genome. Symp Soc Dev Biol. 1976; (34):107-36. PMID: 798339.
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    235. Schrader WT, Schwartz RJ, Kuhn RW, Buller RE, O'Malley BW. Progesterone-receptor mediation of chromatin RNA transcription in a cell-free system. J Toxicol Environ Health Suppl. 1976; 1:77-96. PMID: 1078524.
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    236. Schwartz RJ, Tsai SY, O'Malley BW. Effect of estrogen on gene expression in the chick oviduct. V. Changes in the number of RNA polymerase binding and initiation sites in chromatin. J Biol Chem. 1975 Jul 10; 250(13):5175-82. PMID: 1097440.
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    237. Schwartz RJ, Tsai SY, O'Malley BW. Effects of estrogen on gene expression in the chick oviduct. IV. Initiation of RNA synthesis on DNA and chromatin. J Biol Chem. 1975 Jul 10; 250(13):5165-74. PMID: 1097439.
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    238. Schwartz RJ. Control of glutamine synthetase synthesis in the embryonic chick neural retina. A caution in the use of actinomycin D. J Biol Chem. 1973 Sep 25; 248(18):6426-35. PMID: 4125869.
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