JOSE GARCIA

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address
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    I01CX000174     (GARCIA, JOSE M.)Apr 1, 2009 - Dec 31, 2014
    NIH
    The Role of Ghrelin in Cancer Cachexia
    Role: Principal Investigator

    R21HD060870     (GARCIA, JOSE M.)Sep 3, 2009 - Aug 31, 2011
    NIH
    The role of ghrelin in cisplatin-induced infertility
    Role: Principal Investigator

    I01BX000507     (GARCIA, JOSE M.)Oct 1, 2009 - Sep 30, 2013
    NIH
    Mechanisms of action of ghrelin in muscle and adipose tissue in cancer-related ca
    Role: Principal Investigator

    R03AG040583     (GARCIA, JOSE M.)Aug 15, 2011 - Dec 31, 2014
    NIH
    The role of ghrelin and the ghrelin receptor GHSR1a in sarcopenia of aging
    Role: Principal Investigator

    I01BX002807     (GARCIA, JOSE M.)Oct 1, 2015 - Sep 30, 2023
    NIH
    The Role of Ghrelin and the GHSR-1a receptor in Sarcopenic Obesity
    Role: Principal Investigator

    R01CA239208     (GARCIA, JOSE M.)May 8, 2019 - Apr 30, 2024
    NIH
    Improving Patient-Important Outcomes with Testosterone Replacement in Hypogonadal Men with a Prior History of Cancer
    Role: Principal Investigator

    R01AG061558     (GARCIA, JOSE M.)Aug 1, 2019 - Apr 30, 2024
    NIH
    Improving cancer-related fatigue, sexual dysfunction and quality of life in older men with cancer and androgen deficiency
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Biggerstaff KS, White DL, Frankfort BJ, Richardson P, Orengo-Nania S, Garcia J, Chiao EY, Kramer JR. Gout and open-angle glaucoma risk in a veteran population. Graefes Arch Clin Exp Ophthalmol. 2021 Jul 17. PMID: 34272610.
      Citations:    Fields:    
    2. Barnouin Y, Armamento-Villareal R, Celli A, Jiang B, Paudyal A, Nambi V, Bryant MS, Marcelli M, Garcia JM, Qualls C, Villareal DT. Testosterone Replacement Therapy Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism. J Clin Endocrinol Metab. 2021 03 08; 106(3):e1096-e1110. PMID: 33351921.
      Citations:    Fields:    
    3. White DL, Oluyomi A, Royse K, Dong Y, Nguyen H, Chang E, Richardson P, Jiao L, Garcia JM, Kramer JR, Thrift AP, Chiao E. Incidence of AIDS-Related Kaposi Sarcoma in All 50 United States From 2000 to 2014. J Acquir Immune Defic Syndr. 2019 08 01; 81(4):387-394. PMID: 31242141.
      Citations: 3     Translation:Humans
    4. Wang Z, White DL, Hoogeveen R, Chen L, Whitsel EA, Richardson PA, Virani SS, Garcia JM, El-Serag HB, Jiao L. Anti-Hypertensive Medication Use, Soluble Receptor for Glycation End Products and Risk of Pancreatic Cancer in the Women's Health Initiative Study. J Clin Med. 2018 Aug 02; 7(8). PMID: 30072610.
      Citations: 3     
    5. Calarge CA, Mills JA, Karaviti L, Teixeira AL, Zemel BS, Garcia JM. Selective Serotonin Reuptake Inhibitors Reduce Longitudinal Growth in Risperidone-Treated Boys. J Pediatr. 2018 10; 201:245-251. PMID: 29958671.
      Citations:    Fields:    Translation:Humans
    6. Maldonado M, Molfese DL, Viswanath H, Curtis K, Jones A, Hayes TG, Marcelli M, Mediwala S, Baldwin P, Garcia JM, Salas R. The habenula as a novel link between the homeostatic and hedonic pathways in cancer-associated weight loss: a pilot study. J Cachexia Sarcopenia Muscle. 2018 06; 9(3):497-504. PMID: 29575771.
      Citations: 5     Fields:    Translation:Humans
    7. Guillory B, Jawanmardi N, Iakova P, Anderson B, Zang P, Timchenko NA, Garcia JM. Ghrelin deletion protects against age-associated hepatic steatosis by downregulating the C/EBPa-p300/DGAT1 pathway. Aging Cell. 2018 02; 17(1). PMID: 29024407.
      Citations: 9     Fields:    Translation:AnimalsCells
    8. Guillory B, Chen JA, Patel S, Luo J, Splenser A, Mody A, Ding M, Baghaie S, Anderson B, Iankova B, Halder T, Hernandez Y, Garcia JM. Deletion of ghrelin prevents aging-associated obesity and muscle dysfunction without affecting longevity. Aging Cell. 2017 08; 16(4):859-869. PMID: 28585250.
      Citations: 12     Fields:    Translation:Animals
    9. Mason MC, Garcia JM, Sansgiry S, Walder A, Berger DH, Anaya DA. Preoperative cancer cachexia and short-term outcomes following surgery. J Surg Res. 2016 10; 205(2):398-406. PMID: 27664889.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    10. Braun K, Erickson M, Utech A, List R, Garcia JM. Evaluation of Veterans MOVE! Program for Weight Loss. J Nutr Educ Behav. 2016 05; 48(5):299-303.e1. PMID: 27169639.
      Citations: 2     Fields:    Translation:Humans
    11. Mody A, White D, Kanwal F, Garcia JM. Relevance of low testosterone to non-alcoholic fatty liver disease. Cardiovasc Endocrinol. 2015 Sep 01; 4(3):83-89. PMID: 26405614.
      Citations: 11     
    12. Garcia JM, Chen JA, Guillory B, Donehower LA, Smith RG, Lamb DJ. Ghrelin Prevents Cisplatin-Induced Testicular Damage by Facilitating Repair of DNA Double Strand Breaks Through Activation of p53 in Mice. Biol Reprod. 2015 Jul; 93(1):24. PMID: 26019260.
      Citations: 4     Fields:    Translation:AnimalsCells
    13. Zhang H, Garcia JM. Anamorelin hydrochloride for the treatment of cancer-anorexia-cachexia in NSCLC. Expert Opin Pharmacother. 2015 Jun; 16(8):1245-53. PMID: 25945893.
      Citations: 16     Fields:    Translation:HumansAnimals
    14. Whirledge SD, Garcia JM, Smith RG, Lamb DJ. Ghrelin partially protects against cisplatin-induced male murine gonadal toxicity in a GHSR-1a-dependent manner. Biol Reprod. 2015 Mar; 92(3):76. PMID: 25631345.
      Citations: 8     Fields:    Translation:AnimalsCells
    15. Garcia JM, Boccia RV, Graham CD, Yan Y, Duus EM, Allen S, Friend J. Anamorelin for patients with cancer cachexia: an integrated analysis of two phase 2, randomised, placebo-controlled, double-blind trials. Lancet Oncol. 2015 Jan; 16(1):108-16. PMID: 25524795.
      Citations: 65     Fields:    Translation:Humans
    16. Casal RF, Phan MN, Keshava K, Garcia JM, Grosu H, Lazarus DR, Iribarren J, Rosen DG. The use of endobronchial ultrasound-guided transbronchial needle aspiration in the diagnosis of thyroid lesions. BMC Endocr Disord. 2014 Nov 22; 14:88. PMID: 25416021.
      Citations: 5     Fields:    Translation:Humans
    17. White DL, Liu Y, Garcia J, El-Serag HB, Jiao L, Tsavachidis S, Franco LM, Lee JS, Tavakoli-Tabasi S, Moore D, Goldman R, Kuzniarek J, Ramsey DJ, Kanwal F, Marcelli M. Sex hormone pathway gene polymorphisms are associated with risk of advanced hepatitis C-related liver disease in males. Int J Mol Epidemiol Genet. 2014; 5(3):164-76. PMID: 25379136.
      Citations: 6     
    18. Agrawal V, Garcia JM. The macimorelin-stimulated growth hormone test for adult growth hormone deficiency diagnosis. Expert Rev Mol Diagn. 2014 Jul; 14(6):647-54. PMID: 24834478.
      Citations: 2     Fields:    Translation:Humans
    19. Ali S, Garcia JM. Sarcopenia, cachexia and aging: diagnosis, mechanisms and therapeutic options - a mini-review. Gerontology. 2014; 60(4):294-305. PMID: 24731978.
      Citations: 89     Fields:    Translation:Humans
    20. Mathur S, Boparai J, Mediwala SN, Garcia JM, Cunningham GR, Marcelli M, Vasudevan MM. Reversible Adrenal Insufficiency in Three Patients With Post-Roux-en-Y Gastric Bypass Noninsulinoma Pancreatogenous Hypoglycemia Syndrome. J Investig Med High Impact Case Rep. 2014 Jan-Mar; 2(1):2324709614526992. PMID: 26425596.
      Citations: 1     Fields:    
    21. Ali S, Chen JA, Garcia JM. Clinical development of ghrelin axis-derived molecules for cancer cachexia treatment. Curr Opin Support Palliat Care. 2013 Dec; 7(4):368-75. PMID: 24145681.
      Citations: 13     Fields:    Translation:HumansAnimals
    22. Engineer DR, Burney BO, Hayes TG, Garcia JM. Exposure to ACEI/ARB and ß-Blockers Is Associated with Improved Survival and Decreased Tumor Progression and Hospitalizations in Patients with Advanced Colon Cancer. Transl Oncol. 2013; 6(5):539-45. PMID: 24151534.
      Citations: 15     
    23. Garcia JM, Splenser AE, Kramer J, Alsarraj A, Fitzgerald S, Ramsey D, El-Serag HB. Circulating inflammatory cytokines and adipokines are associated with increased risk of Barrett's esophagus: a case-control study. Clin Gastroenterol Hepatol. 2014 Feb; 12(2):229-238.e3. PMID: 23954649.
      Citations: 34     Fields:    Translation:Humans
    24. Garcia JM, Scherer T, Chen JA, Guillory B, Nassif A, Papusha V, Smiechowska J, Asnicar M, Buettner C, Smith RG. Inhibition of cisplatin-induced lipid catabolism and weight loss by ghrelin in male mice. Endocrinology. 2013 Sep; 154(9):3118-29. PMID: 23832960.
      Citations: 30     Fields:    Translation:AnimalsCells
    25. Garcia JM, Swerdloff R, Wang C, Kyle M, Kipnes M, Biller BM, Cook D, Yuen KC, Bonert V, Dobs A, Molitch ME, Merriam GR. Macimorelin (AEZS-130)-stimulated growth hormone (GH) test: validation of a novel oral stimulation test for the diagnosis of adult GH deficiency. J Clin Endocrinol Metab. 2013 Jun; 98(6):2422-9. PMID: 23559086.
      Citations: 13     Fields:    Translation:Humans
    26. El-Serag HB, Hashmi A, Garcia J, Richardson P, Alsarraj A, Fitzgerald S, Vela M, Shaib Y, Abraham NS, Velez M, Cole R, Rodriguez MB, Anand B, Graham DY, Kramer JR. Visceral abdominal obesity measured by CT scan is associated with an increased risk of Barrett's oesophagus: a case-control study. Gut. 2014 Feb; 63(2):220-9. PMID: 23408348.
      Citations: 42     Fields:    Translation:Humans
    27. Guillory B, Splenser A, Garcia J. The role of ghrelin in anorexia-cachexia syndromes. Vitam Horm. 2013; 92:61-106. PMID: 23601421.
      Citations: 11     Fields:    Translation:HumansAnimals
    28. Garcia JM, Friend J, Allen S. Therapeutic potential of anamorelin, a novel, oral ghrelin mimetic, in patients with cancer-related cachexia: a multicenter, randomized, double-blind, crossover, pilot study. Support Care Cancer. 2013 Jan; 21(1):129-37. PMID: 22699302.
      Citations: 51     Fields:    Translation:Humans
    29. Utech AE, Tadros EM, Hayes TG, Garcia JM. Predicting survival in cancer patients: the role of cachexia and hormonal, nutritional and inflammatory markers. J Cachexia Sarcopenia Muscle. 2012 Dec; 3(4):245-51. PMID: 22648739.
      Citations: 31     Fields:    
    30. Burney BO, Garcia JM. Hypogonadism in male cancer patients. J Cachexia Sarcopenia Muscle. 2012 Sep; 3(3):149-55. PMID: 22528986.
      Citations: 17     Fields:    
    31. Burney BO, Hayes TG, Smiechowska J, Cardwell G, Papusha V, Bhargava P, Konda B, Auchus RJ, Garcia JM. Low testosterone levels and increased inflammatory markers in patients with cancer and relationship with cachexia. J Clin Endocrinol Metab. 2012 May; 97(5):E700-9. PMID: 22419719.
      Citations: 34     Fields:    Translation:Humans
    32. Engineer DR, Garcia JM. Leptin in anorexia and cachexia syndrome. Int J Pept. 2012; 2012:287457. PMID: 22518191.
      Citations: 21     
    33. Garcia JM, Sharafkhaneh H, Hirshkowitz M, Elkhatib R, Sharafkhaneh A. Weight and metabolic effects of CPAP in obstructive sleep apnea patients with obesity. Respir Res. 2011 Jun 15; 12(1):80. PMID: 21676224.
      Citations: 27     Fields:    Translation:HumansCTClinical Trials
    34. Smiechowska J, Utech A, Taffet G, Hayes T, Marcelli M, Garcia JM. Adipokines in patients with cancer anorexia and cachexia. J Investig Med. 2010 Mar; 58(3):554-9. PMID: 20215915.
      Citations: 22     Fields:    Translation:Humans
    35. Sun Y, Butte NF, Garcia JM, Smith RG. Characterization of adult ghrelin and ghrelin receptor knockout mice under positive and negative energy balance. Endocrinology. 2008 Feb; 149(2):843-50. PMID: 18006636.
      Citations: 92     Fields:    Translation:Animals
    36. Garcia JM, Cata JP, Dougherty PM, Smith RG. Ghrelin prevents cisplatin-induced mechanical hyperalgesia and cachexia. Endocrinology. 2008 Feb; 149(2):455-60. PMID: 17962345.
      Citations: 40     Fields:    Translation:Animals
    37. Garcia JM, Polvino WJ. Effect on body weight and safety of RC-1291, a novel, orally available ghrelin mimetic and growth hormone secretagogue: results of a phase I, randomized, placebo-controlled, multiple-dose study in healthy volunteers. Oncologist. 2007 May; 12(5):594-600. PMID: 17522248.
      Citations: 38     Fields:    Translation:HumansCTClinical Trials
    38. Sun Y, Garcia JM, Smith RG. Ghrelin and growth hormone secretagogue receptor expression in mice during aging. Endocrinology. 2007 Mar; 148(3):1323-9. PMID: 17158206.
      Citations: 42     Fields:    Translation:Animals
    39. Garcia JM, Iyer D, Poston WS, Marcelli M, Reeves R, Foreyt J, Balasubramanyam A. Rise of plasma ghrelin with weight loss is not sustained during weight maintenance. Obesity (Silver Spring). 2006 Oct; 14(10):1716-23. PMID: 17062800.
      Citations: 17     Fields:    Translation:Humans
    40. Garcia JM, Li H, Mann D, Epner D, Hayes TG, Marcelli M, Cunningham GR. Hypogonadism in male patients with cancer. Cancer. 2006 Jun 15; 106(12):2583-91. PMID: 16688773.
      Citations: 31     Fields:    Translation:Humans
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