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DAVID HO

TitleClinical Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Urology
Address6560 Fannin Ste# 1001
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Bekdash R, Yoshida K, Nair MS, Qiu L, Ahdout J, Tsai HY, Uryu K, Soni RK, Huang Y, Ho DD, Yazawa M. Developing inhibitory peptides against SARS-CoV-2 envelope protein. PLoS Biol. 2024 Mar; 22(3):e3002522. PMID: 38483887; PMCID: PMC10939250.
      Citations:    Fields:    Translation:HumansAnimalsCells
    2. Tai CG, Haviland MJ, Kissler SM, Lucia RM, Merson M, Maragakis LL, Ho DD, Anderson DJ, DiFiori J, Grubaugh ND, Grad YH, Mack CD. Low antibody levels associated with significantly increased rate of SARS-CoV-2 infection in a highly vaccinated population from the US National Basketball Association. J Med Virol. 2024 Mar; 96(3):e29505. PMID: 38465748.
      Citations:    Fields:    Translation:HumansCells
    3. Wang Q, Guo Y, Bowen A, Mellis IA, Valdez R, Gherasim C, Gordon A, Liu L, Ho DD. XBB.1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against XBB subvariants and JN.1. Cell Host Microbe. 2024 Mar 13; 32(3):315-321.e3. PMID: 38377995; PMCID: PMC10948033.
      Citations: 3     Fields:    Translation:Humans
    4. Yang L, Kim TW, Han Y, Nair MS, Harschnitz O, Zhu J, Wang P, Koo SY, Lacko LA, Chandar V, Bram Y, Zhang T, Zhang W, He F, Pan C, Wu J, Huang Y, Evans T, van der Valk P, Titulaer MJ, Spoor JKH, Furler O'Brien RL, Bugiani M, D J Van de Berg W, Schwartz RE, Ho DD, Studer L, Chen S. SARS-CoV-2 infection causes dopaminergic neuron senescence. Cell Stem Cell. 2024 02 01; 31(2):196-211.e6. PMID: 38237586; PMCID: PMC10843182.
      Citations: 2     Fields:    
    5. Gorman J, Cheung CS, Duan Z, Ou L, Wang M, Chen X, Cheng C, Biju A, Sun Y, Wang P, Yang Y, Zhang B, Boyington JC, Bylund T, Charaf S, Chen SJ, Du H, Henry AR, Liu T, Sarfo EK, Schramm CA, Shen CH, Stephens T, Teng IT, Todd JP, Tsybovsky Y, Verardi R, Wang D, Wang S, Wang Z, Zheng CY, Zhou T, Douek DC, Mascola JR, Ho DD, Ho M, Kwong PD. Cleavage-intermediate Lassa virus trimer elicits neutralizing responses, identifies neutralizing nanobodies, and reveals an apex-situated site-of-vulnerability. Nat Commun. 2024 Jan 04; 15(1):285. PMID: 38177144; PMCID: PMC10767048.
      Citations:    Fields:    Translation:AnimalsCells
    6. Nair MS, Luck MI, Huang Y, Sabo Y, Ho DD, Nair MS, Luck MI, Huang Y, Sabo Y, Ho DD. Persistence of an infectious form of SARS-CoV-2 post protease inhibitor treatment of permissive cells in vitro. bioRxiv. 2023 Dec 21. PMID: 38187654; PMCID: PMC10769372.
      Citations:    
    7. Zhou B, Zhou R, Chan JF, Zeng J, Zhang Q, Yuan S, Liu L, Robinot R, Shan S, Liu N, Ge J, Kwong HY, Zhou D, Xu H, Chan CC, Poon VK, Chu H, Yue M, Kwan KY, Chan CY, Chan CC, Chik KK, Du Z, Au KK, Huang H, Man HO, Cao J, Li C, Wang Z, Zhou J, Song Y, Yeung ML, To KK, Ho DD, Chakrabarti LA, Wang X, Zhang L, Yuen KY, Chen Z. SARS-CoV-2 hijacks neutralizing dimeric IgA for nasal infection and injury in Syrian hamsters1. Emerg Microbes Infect. 2023 Dec; 12(2):2245921. PMID: 37542391; PMCID: PMC10444022.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    8. Wang Q, Yeh AY, Guo Y, Mohri H, Yu J, Ho DD, Liu L. Impaired potency of neutralizing antibodies against cell-cell fusion mediated by SARS-CoV-2. Emerg Microbes Infect. 2023 Dec; 12(1):2210237. PMID: 37132357; PMCID: PMC10215017.
      Citations:    Fields:    Translation:HumansCells
    9. Luo M, Zhou B, Tang B, Chen B, Zhou R, Liu H, Au KK, Man HO, Yuen KY, Dang S, Chen Z, Reddem ER, Liu L, Katsamba PS, To KK, Shapiro L, Ho DD. Structural insights into broadly neutralizing antibodies elicited by hybrid immunity against SARS-CoV-2. Emerg Microbes Infect. 2023 Dec; 12(1):2146538. PMID: 36354024; PMCID: PMC9817130.
      Citations: 1     Fields:    Translation:HumansCells
    10. Jia M, Zhao H, Morano NC, Lu H, Lui YM, Du H, Becker JE, Yuen KY, Ho DD, Kwong PD, Shapiro L, To KK, Wu X. Allosteric Neutralization by Human H7N9 Antibodies. Res Sq. 2023 Nov 07. PMID: 37986867; PMCID: PMC10659534.
      Citations:    
    11. Mack CD, Merson MH, Sims L, Maragakis LL, Davis R, Tai CG, Meisel P, Grad YH, Ho DD, Anderson DJ, LeMay C, DiFiori J. The "Bubble": What Can Be Learned from the National Basketball Association (NBA)'s 2019-20 Season Restart in Orlando during the COVID-19 Pandemic. J Appl Lab Med. 2023 11 02; 8(6):1017-1027. PMID: 37902472.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    12. Wang Q, Bowen A, Ho J, Zhang RM, Valdez R, Stoneman E, Gordon A, Liu L, Ho DD. SARS-CoV-2 neutralising antibodies after a second BA.5 bivalent booster. Lancet. 2023 11 18; 402(10415):1827-1828. PMID: 37922920.
      Citations: 2     Fields:    Translation:HumansCells
    13. Wang Q, Guo Y, Tam AR, Valdez R, Gordon A, Liu L, Ho DD. Deep immunological imprinting due to the ancestral spike in the current bivalent COVID-19 vaccine. Cell Rep Med. 2023 11 21; 4(11):101258. PMID: 37909042; PMCID: PMC10694617.
      Citations: 8     Fields:    Translation:HumansCells
    14. Wang Q, Guo Y, Liu L, Schwanz LT, Li Z, Nair MS, Ho J, Zhang RM, Iketani S, Yu J, Huang Y, Qu Y, Valdez R, Lauring AS, Huang Y, Gordon A, Wang HH, Liu L, Ho DD, Gordon A. Antigenicity and receptor affinity of SARS-CoV-2 BA.2.86 spike. Nature. 2023 Dec; 624(7992):639-644. PMID: 37871613.
      Citations: 20     Fields:    Translation:HumansCells
    15. Wang Q, Li Z, Guo Y, Mellis IA, Iketani S, Liu M, Yu J, Valdez R, Lauring AS, Sheng Z, Gordon A, Liu L, Ho DD. Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2. iScience. 2023 Nov 17; 26(11):108254. PMID: 38026207; PMCID: PMC10654603.
      Citations: 2     
    16. Kissler SM, Hay JA, Fauver JR, Mack C, Tai CG, Anderson DJ, Ho DD, Grubaugh ND, Grad YH. Viral kinetics of sequential SARS-CoV-2 infections. Nat Commun. 2023 10 05; 14(1):6206. PMID: 37798265; PMCID: PMC10556125.
      Citations: 2     Fields:    Translation:HumansCells
    17. Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Immunity. 2023 Oct 10; 56(10):2442-2455.e8. PMID: 37776849; PMCID: PMC10588992.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    18. Duan Y, Zhou H, Liu X, Iketani S, Lin M, Zhang X, Bian Q, Wang H, Sun H, Hong SJ, Culbertson B, Mohri H, Luck MI, Zhu Y, Liu X, Lu Y, Yang X, Yang K, Sabo Y, Chavez A, Goff SP, Rao Z, Ho DD, Yang H. Molecular mechanisms of SARS-CoV-2 resistance to nirmatrelvir. Nature. 2023 Oct; 622(7982):376-382. PMID: 37696289.
      Citations: 3     Fields:    Translation:HumansCells
    19. Wang Q, Guo Y, Zhang RM, Ho J, Mohri H, Valdez R, Manthei DM, Gordon A, Liu L, Ho DD. Antibody neutralisation of emerging SARS-CoV-2 subvariants: EG.5.1 and XBC.1.6. Lancet Infect Dis. 2023 10; 23(10):e397-e398. PMID: 37708906.
      Citations: 12     Fields:    Translation:HumansCells
    20. Tsuji M, Nair MS, Masuda K, Castagna C, Chong Z, Darling TL, Seehra K, Hwang Y, Ribeiro ?L, Ferreira GM, Corredor L, Coelho-Dos-Reis JGA, Tsuji Y, Mori M, Boon ACM, Diamond MS, Huang Y, Ho DD. An immunostimulatory glycolipid that blocks SARS-CoV-2, RSV, and influenza infections in vivo. Nat Commun. 2023 07 05; 14(1):3959. PMID: 37402814; PMCID: PMC10319732.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    21. Burn Aschner C, Muthuraman K, Kucharska I, Cui H, Prieto K, Nair MS, Wang M, Huang Y, Christie-Holmes N, Poon B, Lam J, Sultana A, Kozak R, Mubareka S, Rubinstein JL, Rujas E, Treanor B, Ho DD, Jetha A, Julien JP. A multi-specific, multi-affinity antibody platform neutralizes sarbecoviruses and confers protection against SARS-CoV-2 in vivo. Sci Transl Med. 2023 05 24; 15(697):eadf4549. PMID: 37224226.
      Citations:    Fields:    Translation:HumansAnimalsCells
    22. Sheng Z, Bimela JS, Wang M, Li Z, Guo Y, Ho DD. An optimized thermodynamics integration protocol for identifying beneficial mutations in antibody design. Front Immunol. 2023; 14:1190416. PMID: 37275896; PMCID: PMC10235760.
      Citations:    Fields:    Translation:HumansCells
    23. Liu L, Casner RG, Guo Y, Wang Q, Iketani S, Chan JF, Yu J, Dadonaite B, Nair MS, Mohri H, Reddem ER, Yuan S, Poon VK, Chan CC, Yuen KY, Sheng Z, Huang Y, Bloom JD, Shapiro L, Ho DD. Antibodies that neutralize all current SARS-CoV-2 variants of concern by conformational locking. bioRxiv. 2023 Apr 10. PMID: 37090592; PMCID: PMC10120718.
      Citations:    
    24. Wang Q, Bowen A, Tam AR, Valdez R, Stoneman E, Mellis IA, Gordon A, Liu L, Ho DD. SARS-CoV-2 neutralising antibodies after bivalent versus monovalent booster. Lancet Infect Dis. 2023 05; 23(5):527-528. PMID: 37003292; PMCID: PMC10058662.
      Citations: 2     Fields:    Translation:HumansCells
    25. Nair MS, Ribeiro RM, Wang M, Bowen AD, Liu L, Guo Y, Chang JY, Wang P, Sheng Z, Sobieszczyk ME, Perelson AS, Huang Y, Ho DD. Changes in serum-neutralizing antibody potency and breadth post-SARS-CoV-2 mRNA vaccine boost. iScience. 2023 Apr 21; 26(4):106345. PMID: 36925721; PMCID: PMC9987605.
      Citations:    
    26. Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Chu HY, Neher RA, Bloom JD. A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike. Cell. 2023 03 16; 186(6):1263-1278.e20. PMID: 36868218; PMCID: PMC9922669.
      Citations: 16     Fields:    Translation:HumansCells
    27. Wang Q, Bowen A, Valdez R, Gherasim C, Gordon A, Liu L, Ho DD. Antibody Response to Omicron BA.4-BA.5 Bivalent Booster. N Engl J Med. 2023 02 09; 388(6):567-569. PMID: 36630643; PMCID: PMC9847504.
      Citations: 41     Fields:    Translation:Humans
    28. Wang Q, Iketani S, Li Z, Liu L, Guo Y, Huang Y, Bowen AD, Liu M, Wang M, Yu J, Valdez R, Lauring AS, Sheng Z, Wang HH, Gordon A, Liu L, Ho DD. Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants. Cell. 2023 Jan 19; 186(2):279-286.e8. PMID: 36580913; PMCID: PMC9747694.
      Citations: 139     Fields:    Translation:HumansCells
    29. Wang P, Casner RG, Nair MS, Yu J, Guo Y, Wang M, Chan JF, Cerutti G, Iketani S, Liu L, Sheng Z, Chen Z, Yuen KY, Kwong PD, Huang Y, Shapiro L, Ho DD. A monoclonal antibody that neutralizes SARS-CoV-2 variants, SARS-CoV, and other sarbecoviruses. Emerg Microbes Infect. 2022 Dec; 11(1):147-157. PMID: 34836485; PMCID: PMC8725896.
      Citations:    
    30. Hay JA, Kissler SM, Fauver JR, Mack C, Tai CG, Samant RM, Connolly S, Anderson DJ, Khullar G, MacKay M, Patel M, Kelly S, Manhertz A, Eiter I, Salgado D, Baker T, Howard B, Dudley JT, Mason CE, Nair M, Huang Y, DiFiori J, Ho DD, Grubaugh ND, Grad YH. Quantifying the impact of immune history and variant on SARS-CoV-2 viral kinetics and infection rebound: A retrospective cohort study. Elife. 2022 11 16; 11. PMID: 36383192; PMCID: PMC9711520.
      Citations: 19     Fields:    Translation:HumansCells
    31. Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir. Nature. 2023 01; 613(7944):558-564. PMID: 36351451; PMCID: PMC9849135.
      Citations: 70     Fields:    Translation:HumansCells
    32. Wang Q, Li Z, Ho J, Guo Y, Yeh AY, Mohri H, Liu M, Wang M, Yu J, Shah JG, Chang JY, Herbas F, Yin MT, Sobieszczyk ME, Sheng Z, Liu L, Ho DD. Resistance of SARS-CoV-2 omicron subvariant BA.4.6 to antibody neutralisation. Lancet Infect Dis. 2022 12; 22(12):1666-1668. PMID: 36328002; PMCID: PMC9621396.
      Citations: 26     Fields:    Translation:HumansCells
    33. Dadonaite B, Crawford KHD, Radford CE, Farrell AG, Yu TC, Hannon WW, Zhou P, Andrabi R, Burton DR, Liu L, Ho DD, Neher RA, Bloom JD. A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike. bioRxiv. 2022 Oct 13. PMID: 36263061; PMCID: PMC9580381.
      Citations:    
    34. Charness ME, Gupta K, Stack G, Strymish J, Adams E, Lindy DC, Mohri H, Ho DD. Rebound of SARS-CoV-2 Infection after Nirmatrelvir-Ritonavir Treatment. N Engl J Med. 2022 09 15; 387(11):1045-1047. PMID: 36069968; PMCID: PMC9511633.
      Citations:    
    35. Wang Q, Iketani S, Li Z, Guo Y, Yeh AY, Liu M, Yu J, Sheng Z, Huang Y, Liu L, Ho DD. Antigenic characterization of the SARS-CoV-2 Omicron subvariant BA.2.75. Cell Host Microbe. 2022 11 09; 30(11):1512-1517.e4. PMID: 36108630; PMCID: PMC9444898.
      Citations:    
    36. de Souza MO, Madan B, Teng IT, Huang A, Liu L, Fahad AS, Lopez Acevedo SN, Pan X, Sastry M, Gutierrez-Gonzalez M, Yin MT, Zhou T, Ho DD, Kwong PD, DeKosky BJ. Mapping monoclonal anti-SARS-CoV-2 antibody repertoires against diverse coronavirus antigens. Front Immunol. 2022; 13:977064. PMID: 36119018; PMCID: PMC9478573.
      Citations:    
    37. Mathema B, Chen L, Wang P, Cunningham MH, Mediavilla JR, Chow KF, Luo Y, Zhao Y, Composto K, Zuckerman J, Zody MC, Wilson N, Lee A, Oschwald DM, Liu L, Iketani S, Germer S, Fennessey S, Wang M, Kramer Y, Toole P, Maniatis T, Ho DD, Perlin DS, Kreiswirth BN. Genomic Epidemiology and Serology Associated with a SARS-CoV-2 R.1 Variant Outbreak in New Jersey. mBio. 2022 10 26; 13(5):e0214122. PMID: 35997285; PMCID: PMC9600516.
      Citations:    
    38. Iketani S, Mohri H, Culbertson B, Hong SJ, Duan Y, Luck MI, Annavajhala MK, Guo Y, Sheng Z, Uhlemann AC, Goff SP, Sabo Y, Yang H, Chavez A, Ho DD. Multiple pathways for SARS-CoV-2 resistance to nirmatrelvir. bioRxiv. 2022 Aug 18. PMID: 36032976; PMCID: PMC9413711.
      Citations:    
    39. Iketani S, Hong SJ, Sheng J, Bahari F, Culbertson B, Atanaki FF, Aditham AK, Kratz AF, Luck MI, Tian R, Goff SP, Montazeri H, Sabo Y, Ho DD, Chavez A. Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites. Cell Host Microbe. 2022 10 12; 30(10):1354-1362.e6. PMID: 36029764; PMCID: PMC9365866.
      Citations:    
    40. Iketani S, Hong SJ, Sheng J, Bahari F, Culbertson B, Atanaki FF, Aditham AK, Kratz AF, Luck MI, Tian R, Goff SP, Montazeri H, Sabo Y, Ho DD, Chavez A. The Functional Landscape of SARS-CoV-2 3CL Protease. bioRxiv. 2022 Jul 12. PMID: 35860222; PMCID: PMC9298129.
      Citations:    
    41. Wang Q, Guo Y, Iketani S, Nair MS, Li Z, Mohri H, Wang M, Yu J, Bowen AD, Chang JY, Shah JG, Nguyen N, Chen Z, Meyers K, Yin MT, Sobieszczyk ME, Sheng Z, Huang Y, Liu L, Ho DD. Antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4 and BA.5. Nature. 2022 08; 608(7923):603-608. PMID: 35790190; PMCID: PMC9385487.
      Citations:    
    42. Liu L, Iketani S, Guo Y, Reddem ER, Casner RG, Nair MS, Yu J, Chan JF, Wang M, Cerutti G, Li Z, Morano NC, Castagna CD, Corredor L, Chu H, Yuan S, Poon VK, Chan CC, Chen Z, Luo Y, Cunningham M, Chavez A, Yin MT, Perlin DS, Tsuji M, Yuen KY, Kwong PD, Sheng Z, Huang Y, Shapiro L, Ho DD. An antibody class with a common CDRH3 motif broadly neutralizes sarbecoviruses. Sci Transl Med. 2022 05 25; 14(646):eabn6859. PMID: 35438546; PMCID: PMC9017343.
      Citations:    
    43. Wang Q, Anang S, Iketani S, Guo Y, Liu L, Katsamba PS, Shapiro L, Ho DD, Sodroski JG. Functional properties of the spike glycoprotein of the emerging SARS-CoV-2 variant B.1.1.529. Cell Rep. 2022 06 14; 39(11):110924. PMID: 35658975; PMCID: PMC9119962.
      Citations:    
    44. Liu L, Meyers K, Purpura LJ, Nguyen N, Mohri H, Chang JY, Annavajhala MK, Lopez L, Lee SW, Shah J, Lane B, Cantos A, Tukuru SA, Guo Y, Ford K, Chiu YT, Sheng Z, Choesang T, Castor D, Wang M, Pili C, Van Hoy MN, Wallach A, Horton J, Chen Z, Rosenthal S, McLaren S, Jiang B, Wang F, Lu HH, Uhlemann AC, Ho DD, Yin MT. Development and performance of a point-of-care rapid antigen test for detection of SARS-COV-2 variants. J Clin Virol Plus. 2022 Aug; 2(3):100080. PMID: 35528048; PMCID: PMC9067019.
      Citations:    
    45. Liu H, Iketani S, Zask A, Khanizeman N, Bednarova E, Forouhar F, Fowler B, Hong SJ, Mohri H, Nair MS, Huang Y, Tay NES, Lee S, Karan C, Resnick SJ, Quinn C, Li W, Shion H, Xia X, Daniels JD, Bartolo-Cruz M, Farina M, Rajbhandari P, Jurtschenko C, Lauber MA, McDonald T, Stokes ME, Hurst BL, Rovis T, Chavez A, Ho DD, Stockwell BR. Development of optimized drug-like small molecule inhibitors of the SARS-CoV-2 3CL protease for treatment of COVID-19. Nat Commun. 2022 04 07; 13(1):1891. PMID: 35393402; PMCID: PMC8989888.
      Citations:    
    46. DeGrace MM, Ghedin E, Frieman MB, Krammer F, Grifoni A, Alisoltani A, Alter G, Amara RR, Baric RS, Barouch DH, Bloom JD, Bloyet LM, Bonenfant G, Boon ACM, Boritz EA, Bratt DL, Bricker TL, Brown L, Buchser WJ, Carre?o JM, Cohen-Lavi L, Darling TL, Davis-Gardner ME, Dearlove BL, Di H, Dittmann M, Doria-Rose NA, Douek DC, Drosten C, Edara VV, Ellebedy A, Fabrizio TP, Ferrari G, Fischer WM, Florence WC, Fouchier RAM, Franks J, Garc?a-Sastre A, Godzik A, Gonzalez-Reiche AS, Gordon A, Haagmans BL, Halfmann PJ, Ho DD, Holbrook MR, Huang Y, James SL, Jaroszewski L, Jeevan T, Johnson RM, Jones TC, Joshi A, Kawaoka Y, Kercher L, Koopmans MPG, Korber B, Koren E, Koup RA, LeGresley EB, Lemieux JE, Liebeskind MJ, Liu Z, Livingston B, Logue JP, Luo Y, McDermott AB, McElrath MJ, Meliopoulos VA, Menachery VD, Montefiori DC, M?hlemann B, Munster VJ, Munt JE, Nair MS, Netzl A, Niewiadomska AM, O'Dell S, Pekosz A, Perlman S, Pontelli MC, Rockx B, Rolland M, Rothlauf PW, Sacharen S, Scheuermann RH, Schmidt SD, Schotsaert M, Schultz-Cherry S, Seder RA, Sedova M, Sette A, Shabman RS, Shen X, Shi PY, Shukla M, Simon V, Stumpf S, Sullivan NJ, Thackray LB, Theiler J, Thomas PG, Trifkovic S, T?reli S, Turner SA, Vakaki MA, van Bakel H, VanBlargan LA, Vincent LR, Wallace ZS, Wang L, Wang M, Wang P, Wang W, Weaver SC, Webby RJ, Weiss CD, Wentworth DE, Weston SM, Whelan SPJ, Whitener BM, Wilks SH, Xie X, Ying B, Yoon H, Zhou B, Hertz T, Smith DJ, Diamond MS, Post DJ, Suthar MS. Defining the risk of SARS-CoV-2 variants on immune protection. Nature. 2022 05; 605(7911):640-652. PMID: 35361968; PMCID: PMC9345323.
      Citations:    
    47. Han Y, Zhu J, Yang L, Nilsson-Payant BE, Hurtado R, Lacko LA, Sun X, Gade AR, Higgins CA, Sisso WJ, Dong X, Wang M, Chen Z, Ho DD, Pitt GS, Schwartz RE, tenOever BR, Evans T, Chen S. SARS-CoV-2 Infection Induces Ferroptosis of Sinoatrial Node Pacemaker Cells. Circ Res. 2022 04; 130(7):963-977. PMID: 35255712; PMCID: PMC8963443.
      Citations:    
    48. Iketani S, Liu L, Guo Y, Liu L, Chan JF, Huang Y, Wang M, Luo Y, Yu J, Chu H, Chik KK, Yuen TT, Yin MT, Sobieszczyk ME, Huang Y, Yuen KY, Wang HH, Sheng Z, Ho DD. Antibody evasion properties of SARS-CoV-2 Omicron sublineages. Nature. 2022 04; 604(7906):553-556. PMID: 35240676; PMCID: PMC9021018.
      Citations:    
    49. Duan X, Wang H, Ho DD, Schwartz RE, Evans T, Chen S. Comments on 'An airway organoid-based screen identifies a role for the HIF1a?glycolysis axis in SARS-CoV-2 infection'. J Mol Cell Biol. 2022 02 24; 14(1). PMID: 34850919; PMCID: PMC8690227.
      Citations:    
    50. Joyce MG, King HAD, Elakhal-Naouar I, Ahmed A, Peachman KK, Macedo Cincotta C, Subra C, Chen RE, Thomas PV, Chen WH, Sankhala RS, Hajduczki A, Martinez EJ, Peterson CE, Chang WC, Choe M, Smith C, Lee PJ, Headley JA, Taddese MG, Elyard HA, Cook A, Anderson A, McGuckin Wuertz K, Dong M, Swafford I, Case JB, Currier JR, Lal KG, Molnar S, Nair MS, Dussupt V, Daye SP, Zeng X, Barkei EK, Staples HM, Alfson K, Carrion R, Krebs SJ, Paquin-Proulx D, Karasavva N, Polonis VR, Jagodzinski LL, Amare MF, Vasan S, Scott PT, Huang Y, Ho DD, de Val N, Diamond MS, Lewis MG, Rao M, Matyas GR, Gromowski GD, Peel SA, Michael NL, Bolton DL, Modjarrad K. A SARS-CoV-2 ferritin nanoparticle vaccine elicits protective immune responses in nonhuman primates. Sci Transl Med. 2022 Feb 16; 14(632):eabi5735. PMID: 34914540.
      Citations:    
    51. Cerutti G, Guo Y, Liu L, Liu L, Zhang Z, Luo Y, Huang Y, Wang HH, Ho DD, Sheng Z, Shapiro L. Cryo-EM structure of the SARS-CoV-2 Omicron spike. Cell Rep. 2022 03 01; 38(9):110428. PMID: 35172173; PMCID: PMC8818377.
      Citations:    
    52. Liu L, Iketani S, Guo Y, Chan JF, Wang M, Liu L, Luo Y, Chu H, Huang Y, Nair MS, Yu J, Chik KK, Yuen TT, Yoon C, To KK, Chen H, Yin MT, Sobieszczyk ME, Huang Y, Wang HH, Sheng Z, Yuen KY, Ho DD. Striking antibody evasion manifested by the Omicron variant of SARS-CoV-2. Nature. 2022 02; 602(7898):676-681. PMID: 35016198.
      Citations:    
    53. Ke R, Zitzmann C, Ho DD, Ribeiro RM, Perelson AS. In vivo kinetics of SARS-CoV-2 infection and its relationship with a person's infectiousness. Proc Natl Acad Sci U S A. 2021 12 07; 118(49). PMID: 34857628; PMCID: PMC8670484.
      Citations:    
    54. Kissler SM, Fauver JR, Mack C, Tai CG, Breban MI, Watkins AE, Samant RM, Anderson DJ, Metti J, Khullar G, Baits R, MacKay M, Salgado D, Baker T, Dudley JT, Mason CE, Ho DD, Grubaugh ND, Grad YH. Viral Dynamics of SARS-CoV-2 Variants in Vaccinated and Unvaccinated Persons. N Engl J Med. 2021 12 23; 385(26):2489-2491. PMID: 34941024; PMCID: PMC8693673.
      Citations:    
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    107. Zhou T, Tsybovsky Y, Olia AS, Gorman J, Rapp MA, Cerutti G, Chuang GY, Katsamba PS, Nazzari A, Sampson JM, Schon A, Wang PD, Bimela J, Shi W, Teng IT, Zhang B, Boyington JC, Sastry M, Stephens T, Stuckey J, Wang S, Friesner RA, Ho DD, Mascola JR, Shapiro L, Kwong PD. Cryo-EM Structures Delineate a pH-Dependent Switch that Mediates Endosomal Positioning of SARS-CoV-2 Spike Receptor-Binding Domains. bioRxiv. 2020 Jul 31. PMID: 32637958; PMCID: PMC7337388.
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    108. Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent neutralizing antibodies against multiple epitopes on SARS-CoV-2 spike. Nature. 2020 08; 584(7821):450-456. PMID: 32698192.
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    109. Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Acevedo SNL, Madan B, de Souza MO, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. SSRN. 2020 Jul 21; 3639618. PMID: 32742241; PMCID: PMC7385481.
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    110. Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike. bioRxiv. 2020 Jul 16. PMID: 32587975; PMCID: PMC7310634.
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    111. Wang P, Gajjar MR, Yu J, Padte NN, Gettie A, Blanchard JL, Russell-Lodrigue K, Liao LE, Perelson AS, Huang Y, Ho DD. Quantifying the contribution of Fc-mediated effector functions to the antiviral activity of anti-HIV-1 IgG1 antibodies in vivo. Proc Natl Acad Sci U S A. 2020 07 28; 117(30):18002-18009. PMID: 32665438; PMCID: PMC7395461.
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    112. Gupta A, Madhavan MV, Sehgal K, Nair N, Mahajan S, Sehrawat TS, Bikdeli B, Ahluwalia N, Ausiello JC, Wan EY, Freedberg DE, Kirtane AJ, Parikh SA, Maurer MS, Nordvig AS, Accili D, Bathon JM, Mohan S, Bauer KA, Leon MB, Krumholz HM, Uriel N, Mehra MR, Elkind MSV, Stone GW, Schwartz A, Ho DD, Bilezikian JP, Landry DW. Extrapulmonary manifestations of COVID-19. Nat Med. 2020 07; 26(7):1017-1032. PMID: 32651579.
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    113. Zhou T, Teng IT, Olia AS, Cerutti G, Gorman J, Nazzari A, Shi W, Tsybovsky Y, Wang L, Wang S, Zhang B, Zhang Y, Katsamba PS, Petrova Y, Banach BB, Fahad AS, Liu L, Lopez Acevedo SN, Madan B, de Souza MO, Pan X, Wang P, Wolfe JR, Yin M, Ho DD, Phung E, DiPiazza A, Chang L, Abiona O, Corbett KS, DeKosky BJ, Graham BS, Mascola JR, Misasi J, Ruckwardt T, Sullivan NJ, Shapiro L, Kwong PD. Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes. bioRxiv. 2020 Jun 23. PMID: 32596696; PMCID: PMC7315997.
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    114. Yang L, Han Y, Nilsson-Payant BE, Gupta V, Wang P, Duan X, Tang X, Zhu J, Zhao Z, Jaffr? F, Zhang T, Kim TW, Harschnitz O, Redmond D, Houghton S, Liu C, Naji A, Ciceri G, Guttikonda S, Bram Y, Nguyen DT, Cioffi M, Chandar V, Hoagland DA, Huang Y, Xiang J, Wang H, Lyden D, Borczuk A, Chen HJ, Studer L, Pan FC, Ho DD, tenOever BR, Evans T, Schwartz RE, Chen S. A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids. Cell Stem Cell. 2020 07 02; 27(1):125-136.e7. PMID: 32579880; PMCID: PMC7303620.
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    115. Han Y, Yang L, Duan X, Duan F, Nilsson-Payant BE, Yaron TM, Wang P, Tang X, Zhang T, Zhao Z, Bram Y, Redmond D, Houghton S, Nguyen D, Xu D, Wang X, Uhl S, Huang Y, Johnson JL, Xiang J, Wang H, Pan FC, Cantley LC, tenOever BR, Ho DD, Evans T, Schwartz RE, Chen HJ, Chen S. Identification of Candidate COVID-19 Therapeutics using hPSC-derived Lung Organoids. bioRxiv. 2020 May 05. PMID: 32511403; PMCID: PMC7263550.
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    116. Jia M, Liberatore RA, Guo Y, Chan KW, Pan R, Lu H, Waltari E, Mittler E, Chandran K, Finzi A, Kaufmann DE, Seaman MS, Ho DD, Shapiro L, Sheng Z, Kong XP, Bieniasz PD, Wu X. VSV-Displayed HIV-1 Envelope Identifies Broadly Neutralizing Antibodies Class-Switched to IgG and IgA. Cell Host Microbe. 2020 06 10; 27(6):963-975.e5. PMID: 32315598; PMCID: PMC7294236.
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    117. Rathore A, Iketani S, Wang P, Jia M, Sahi V, Ho DD. CRISPR-based gene knockout screens reveal deubiquitinases involved in HIV-1 latency in two Jurkat cell models. Sci Rep. 2020 03 24; 10(1):5350. PMID: 32210344; PMCID: PMC7093534.
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    118. Liberatore RA, Ho DD. The Miami Monkey: A Sunny Alternative to the Berlin Patient. Immunity. 2019 03 19; 50(3):537-539. PMID: 30893580.
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    119. Padte NN, Yu J, Huang Y, Ho DD. Engineering multi-specific antibodies against HIV-1. Retrovirology. 2018 08 29; 15(1):60. PMID: 30157871; PMCID: PMC6114543.
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    120. Wagh K, Seaman MS, Zingg M, Fitzsimons T, Barouch DH, Burton DR, Connors M, Ho DD, Mascola JR, Nussenzweig MC, Ravetch J, Gautam R, Martin MA, Montefiori DC, Korber B. Potential of conventional & bispecific broadly neutralizing antibodies for prevention of HIV-1 subtype A, C & D infections. PLoS Pathog. 2018 03; 14(3):e1006860. PMID: 29505593; PMCID: PMC5854441.
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    121. Mukhopadhyay M, Galperin M, Patgaonkar M, Vasan S, Ho DD, Nou?l A, Claireaux M, Benati D, Lambotte O, Huang Y, Chakrabarti LA. DNA Vaccination by Electroporation Amplifies Broadly Cross-Restricted Public TCR Clonotypes Shared with HIV Controllers. J Immunol. 2017 11 15; 199(10):3437-3452. PMID: 28993513; PMCID: PMC5675813.
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    122. Andrews CD, Luo Y, Sun M, Yu J, Goff AJ, Glass PJ, Padte NN, Huang Y, Ho DD. In?Vivo Production of Monoclonal Antibodies by Gene Transfer via Electroporation Protects against Lethal Influenza and Ebola Infections. Mol Ther Methods Clin Dev. 2017 Dec 15; 7:74-82. PMID: 29034261; PMCID: PMC5633264.
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    123. Andrews CD, Bernard LS, Poon AY, Mohri H, Gettie N, Spreen WR, Gettie A, Russell-Lodrigue K, Blanchard J, Hong Z, Ho DD, Markowitz M. Cabotegravir long acting injection protects macaques against intravenous challenge with SIVmac251. AIDS. 2017 02 20; 31(4):461-467. PMID: 27902508; PMCID: PMC5263045.
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    124. Song R, Pace C, Seaman MS, Fang Q, Sun M, Andrews CD, Wu A, Padte NN, Ho DD. Distinct HIV-1 Neutralization Potency Profiles of Ibalizumab-Based Bispecific Antibodies. J Acquir Immune Defic Syndr. 2016 Dec 01; 73(4):365-373. PMID: 27792681; PMCID: PMC5123706.
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    125. Huang Y, Yu J, Lanzi A, Yao X, Andrews CD, Tsai L, Gajjar MR, Sun M, Seaman MS, Padte NN, Ho DD. Engineered Bispecific Antibodies with Exquisite HIV-1-Neutralizing Activity. Cell. 2016 Jun 16; 165(7):1621-1631. PMID: 27315479; PMCID: PMC4972332.
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    126. Kwon YD, Georgiev IS, Ofek G, Zhang B, Asokan M, Bailer RT, Bao A, Caruso W, Chen X, Choe M, Druz A, Ko SY, Louder MK, McKee K, O'Dell S, Pegu A, Rudicell RS, Shi W, Wang K, Yang Y, Alger M, Bender MF, Carlton K, Cooper JW, Blinn J, Eudailey J, Lloyd K, Parks R, Alam SM, Haynes BF, Padte NN, Yu J, Ho DD, Huang J, Connors M, Schwartz RM, Mascola JR, Kwong PD. Optimization of the Solubility of HIV-1-Neutralizing Antibody 10E8 through Somatic Variation and Structure-Based Design. J Virol. 2016 07 01; 90(13):5899-5914. PMID: 27053554; PMCID: PMC4907239.
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    127. Morgand M, Bouvin-Pley M, Plantier JC, Moreau A, Alessandri E, Simon F, Pace CS, Pancera M, Ho DD, Poignard P, Bjorkman PJ, Mouquet H, Nussenzweig MC, Kwong PD, Baty D, Chames P, Braibant M, Barin F. V1/V2 Neutralizing Epitope is Conserved in Divergent Non-M Groups of HIV-1. J Acquir Immune Defic Syndr. 2016 Mar 01; 71(3):237-45. PMID: 26413851; PMCID: PMC4770367.
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    128. Ghose C, Eugenis I, Sun X, Edwards AN, McBride SM, Pride DT, Kelly CP, Ho DD. Immunogenicity and protective efficacy of recombinant Clostridium difficile flagellar protein FliC. Emerg Microbes Infect. 2016 Feb 03; 5:e8. PMID: 26839147; PMCID: PMC4777929.
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    129. Ghose C, Eugenis I, Edwards AN, Sun X, McBride SM, Ho DD. Immunogenicity and protective efficacy of Clostridium difficile spore proteins. Anaerobe. 2016 Feb; 37:85-95. PMID: 26688279; PMCID: PMC4770901.
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    130. Li X, Kawamura A, Andrews CD, Miller JL, Wu D, Tsao T, Zhang M, Oren D, Padte NN, Porcelli SA, Wong CH, Kappe SH, Ho DD, Tsuji M. Colocalization of a CD1d-Binding Glycolipid with a Radiation-Attenuated Sporozoite Vaccine in Lymph Node-Resident Dendritic Cells for a Robust Adjuvant Effect. J Immunol. 2015 Sep 15; 195(6):2710-21. PMID: 26254338; PMCID: PMC4561196.
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    131. Barbian HJ, Decker JM, Bibollet-Ruche F, Galimidi RP, West AP, Learn GH, Parrish NF, Iyer SS, Li Y, Pace CS, Song R, Huang Y, Denny TN, Mouquet H, Acharya P, Zhang B, Kwong PD, Mascola JR, Verrips CT, Strokappe NM, Rutten L, McCoy LE, Weiss RA, Brown CS, Jackson R, Silvestri G, Connors M, Burton DR, Shaw GM, Nussenzweig MC, Bjorkman PJ, Ho DD, Farzan M, Hahn BH, Martin L. Neutralization properties of simian immunodeficiency viruses infecting chimpanzees and gorillas. mBio. 2015 Apr 21; 6(2). PMID: 25900654; PMCID: PMC4453581.
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    132. Andrews CD, Yueh YL, Spreen WR, St Bernard L, Boente-Carrera M, Rodriguez K, Gettie A, Russell-Lodrigue K, Blanchard J, Ford S, Mohri H, Cheng-Mayer C, Hong Z, Ho DD, Markowitz M. A long-acting integrase inhibitor protects female macaques from repeated high-dose intravaginal SHIV challenge. Sci Transl Med. 2015 Jan 14; 7(270):270ra4. PMID: 25589630; PMCID: PMC4449736.
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    133. Venkataswamy MM, Ng TW, Kharkwal SS, Johnson AJ, Kunnath-Velayudhan S, Liu Z, Bittman R, Jervis PJ, Cox LR, Besra GS, Wen X, Yuan W, Tsuji M, Li X, Ho DD, Chan J, Lee S, Frothingham R, Haynes BF, Panas MW, Gillard GO, Sixsmith JD, Korioth-Schmitz B, Schmitz JE, Larsen MH, Jacobs WR, Porcelli SA, Carre?o LJ. Improving Mycobacterium bovis bacillus Calmette-Gu?rin as a vaccine delivery vector for viral antigens by incorporation of glycolipid activators of NKT cells. PLoS One. 2014; 9(9):e108383. PMID: 25255287; PMCID: PMC4177913.
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    134. Pace CS, Yao X, Yu F, Padte NN, Huang Y, Seaman MS, Li Q, Ho DD, Sun M. Rational design and characterization of the novel, broad and potent bispecific HIV-1 neutralizing antibody iMabm36. J Acquir Immune Defic Syndr. 2014 Aug 15; 66(5):473-83. PMID: 24853313; PMCID: PMC4163016.
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    135. Andrews CD, Spreen WR, Mohri H, Moss L, Ford S, Gettie A, Russell-Lodrigue K, Bohm RP, Cheng-Mayer C, Hong Z, Markowitz M, Ho DD. Long-acting integrase inhibitor protects macaques from intrarectal simian/human immunodeficiency virus. Science. 2014 Mar 07; 343(6175):1151-4. PMID: 24594934; PMCID: PMC4308974.
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    136. Xiao H, Liu L, Zhu Q, Tan Z, Yu W, Tang X, Zhan D, Du Y, Wang H, Liu D, Li Z, Yuen KY, Ho DD, Gao GF, Chen Z. A replicating modified vaccinia tiantan strain expressing an avian-derived influenza H5N1 hemagglutinin induce broadly neutralizing antibodies and cross-clade protective immunity in mice. PLoS One. 2013; 8(12):e83274. PMID: 24358269; PMCID: PMC3866202.
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    137. Padte NN, Boente-Carrera M, Andrews CD, McManus J, Grasperge BF, Gettie A, Coelho-dos-Reis JG, Li X, Wu D, Bruder JT, Sedegah M, Patterson N, Richie TL, Wong CH, Ho DD, Vasan S, Tsuji M. A glycolipid adjuvant, 7DW8-5, enhances CD8+ T cell responses induced by an adenovirus-vectored malaria vaccine in non-human primates. PLoS One. 2013; 8(10):e78407. PMID: 24205224; PMCID: PMC3808339.
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    138. Song R, Oren DA, Franco D, Seaman MS, Ho DD. Strategic addition of an N-linked glycan to a monoclonal antibody improves its HIV-1-neutralizing activity. Nat Biotechnol. 2013 Nov; 31(11):1047-52. PMID: 24097413; PMCID: PMC3825789.
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    139. Pace CS, Song R, Ochsenbauer C, Andrews CD, Franco D, Yu J, Oren DA, Seaman MS, Ho DD. Bispecific antibodies directed to CD4 domain 2 and HIV envelope exhibit exceptional breadth and picomolar potency against HIV-1. Proc Natl Acad Sci U S A. 2013 Aug 13; 110(33):13540-5. PMID: 23878231; PMCID: PMC3746901.
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    140. Ghose C, Verhagen JM, Chen X, Yu J, Huang Y, Chenesseau O, Ho DD, Kelly CP. Toll-like receptor 5-dependent immunogenicity and protective efficacy of a recombinant fusion protein vaccine containing the nontoxic domains of Clostridium difficile toxins A and B and Salmonella enterica serovar typhimurium flagellin in a mouse model of Clostridium difficile disease. Infect Immun. 2013 Jun; 81(6):2190-6. PMID: 23545305; PMCID: PMC3676027.
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    141. Pace CS, Fordyce MW, Franco D, Kao CY, Seaman MS, Ho DD. Anti-CD4 monoclonal antibody ibalizumab exhibits breadth and potency against HIV-1, with natural resistance mediated by the loss of a V5 glycan in envelope. J Acquir Immune Defic Syndr. 2013 Jan 01; 62(1):1-9. PMID: 23023102.
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    142. Zaharatos GJ, Yu J, Pace C, Song Y, Vasan S, Ho DD, Huang Y. HIV-1 and influenza antigens synthetically linked to IgG2a Fc elicit superior humoral responses compared to unmodified antigens in mice. Vaccine. 2011 Dec 09; 30(1):42-50. PMID: 22064264.
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    143. Scheid JF, Mouquet H, Ueberheide B, Diskin R, Klein F, Oliveira TY, Pietzsch J, Fenyo D, Abadir A, Velinzon K, Hurley A, Myung S, Boulad F, Poignard P, Burton DR, Pereyra F, Ho DD, Walker BD, Seaman MS, Bjorkman PJ, Chait BT, Nussenzweig MC. Sequence and structural convergence of broad and potent HIV antibodies that mimic CD4 binding. Science. 2011 Sep 16; 333(6049):1633-7. PMID: 21764753; PMCID: PMC3351836.
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    144. Vasan S, Hurley A, Schlesinger SJ, Hannaman D, Gardiner DF, Dugin DP, Boente-Carrera M, Vittorino R, Caskey M, Andersen J, Huang Y, Cox JH, Tarragona-Fiol T, Gill DK, Cheeseman H, Clark L, Dally L, Smith C, Schmidt C, Park HH, Kopycinski JT, Gilmour J, Fast P, Bernard R, Ho DD. In vivo electroporation enhances the immunogenicity of an HIV-1 DNA vaccine candidate in healthy volunteers. PLoS One. 2011; 6(5):e19252. PMID: 21603651; PMCID: PMC3095594.
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    145. Franco D, Liu W, Gardiner DF, Hahn BH, Ho DD. CD40L-containing virus-like particle as a candidate HIV-1 vaccine targeting dendritic cells. J Acquir Immune Defic Syndr. 2011 Apr 15; 56(5):393-400. PMID: 21239998.
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    146. Chen MW, Liao HY, Huang Y, Jan JT, Huang CC, Ren CT, Wu CY, Cheng TJ, Ho DD, Wong CH. Broadly neutralizing DNA vaccine with specific mutation alters the antigenicity and sugar-binding activities of influenza hemagglutinin. Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3510-5. PMID: 21321237; PMCID: PMC3048126.
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    147. Liao CF, Wang SF, Lin YT, Ho DD, Chen YM. Identification of the DC-SIGN-interactive domains on the envelope glycoprotein of HIV-1 CRF07_BC. AIDS Res Hum Retroviruses. 2011 Aug; 27(8):831-9. PMID: 21142800.
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    148. Freeman MM, Seaman MS, Rits-Volloch S, Hong X, Kao CY, Ho DD, Chen B. Crystal structure of HIV-1 primary receptor CD4 in complex with a potent antiviral antibody. Structure. 2010 Dec 08; 18(12):1632-41. PMID: 21134642; PMCID: PMC3005625.
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    149. Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, Chakraborty AK, Hope TJ, Ravetch JV, Wardemann H, Nussenzweig MC. Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation. Nature. 2010 Sep 30; 467(7315):591-5. PMID: 20882016; PMCID: PMC3699875.
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    150. Li X, Fujio M, Imamura M, Wu D, Vasan S, Wong CH, Ho DD, Tsuji M. Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant. Proc Natl Acad Sci U S A. 2010 Jul 20; 107(29):13010-5. PMID: 20616071; PMCID: PMC2919905.
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    151. Franco D, Li W, Qing F, Stoyanov CT, Moran T, Rice CM, Ho DD. Evaluation of yellow fever virus 17D strain as a new vector for HIV-1 vaccine development. Vaccine. 2010 Aug 09; 28(35):5676-85. PMID: 20600494.
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    152. Song R, Franco D, Kao CY, Yu F, Huang Y, Ho DD. Epitope mapping of ibalizumab, a humanized anti-CD4 monoclonal antibody with anti-HIV-1 activity in infected patients. J Virol. 2010 Jul; 84(14):6935-42. PMID: 20463063; PMCID: PMC2898252.
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    153. Zhou Z, Meyers K, Li X, Chen Q, Qian H, Lao Y, Geng E, Fan Y, Yang S, Chiu M, Ho DD. Prevention of mother-to-child transmission of HIV-1 using highly active antiretroviral therapy in rural Yunnan, China. J Acquir Immune Defic Syndr. 2010 Feb; 53 Suppl 1:S15-22. PMID: 20104104.
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    154. Vasan S, Schlesinger SJ, Huang Y, Hurley A, Lombardo A, Chen Z, Than S, Adesanya P, Bunce C, Boaz M, Boyle R, Sayeed E, Clark L, Dugin D, Schmidt C, Song Y, Seamons L, Dally L, Ho M, Smith C, Markowitz M, Cox J, Gill DK, Gilmour J, Keefer MC, Fast P, Ho DD. Phase 1 safety and immunogenicity evaluation of ADVAX, a multigenic, DNA-based clade C/B' HIV-1 candidate vaccine. PLoS One. 2010 Jan 25; 5(1):e8617. PMID: 20111582; PMCID: PMC2799527.
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    155. Vasan S, Schlesinger SJ, Chen Z, Hurley A, Lombardo A, Than S, Adesanya P, Bunce C, Boaz M, Boyle R, Sayeed E, Clark L, Dugin D, Boente-Carrera M, Schmidt C, Fang Q, Huang Y, Zaharatos GJ, Gardiner DF, Caskey M, Seamons L, Ho M, Dally L, Smith C, Cox J, Gill D, Gilmour J, Keefer MC, Fast P, Ho DD. Phase 1 safety and immunogenicity evaluation of ADMVA, a multigenic, modified vaccinia Ankara-HIV-1 B'/C candidate vaccine. PLoS One. 2010 Jan 25; 5(1):e8816. PMID: 20111599; PMCID: PMC2810329.
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    156. Liang K, Gui X, Zhang YZ, Zhuang K, Meyers K, Ho DD. A case series of 104 women infected with HIV-1 via blood transfusion postnatally: high rate of HIV-1 transmission to infants through breast-feeding. J Infect Dis. 2009 Sep 01; 200(5):682-6. PMID: 19627245.
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    157. Gardiner DF, Rosenberg T, Zaharatos J, Franco D, Ho DD. A DNA vaccine targeting the receptor-binding domain of Clostridium difficile toxin A. Vaccine. 2009 Jun 02; 27(27):3598-604. PMID: 19464540; PMCID: PMC2709243.
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    158. Gunnell D, Hawton K, Ho D, Evans J, O'Connor S, Potokar J, Donovan J, Kapur N. Hospital admissions for self harm after discharge from psychiatric inpatient care: cohort study. BMJ. 2008 Nov 18; 337:a2278. PMID: 19018041; PMCID: PMC2590882.
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    159. Lu L, Jia M, Ma Y, Yang L, Chen Z, Ho DD, Jiang Y, Zhang L. The changing face of HIV in China. Nature. 2008 Oct 02; 455(7213):609-11. PMID: 18833270.
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    160. Huang Y, Krasnitz M, Rabadan R, Witten DM, Song Y, Levine AJ, Ho DD, Robins H. A recoding method to improve the humoral immune response to an HIV DNA vaccine. PLoS One. 2008 Sep 15; 3(9):e3214. PMID: 18791646; PMCID: PMC2529374.
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    161. Chen MW, Cheng TJ, Huang Y, Jan JT, Ma SH, Yu AL, Wong CH, Ho DD. A consensus-hemagglutinin-based DNA vaccine that protects mice against divergent H5N1 influenza viruses. Proc Natl Acad Sci U S A. 2008 Sep 09; 105(36):13538-43. PMID: 18765801; PMCID: PMC2533225.
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    162. Ho DD, Bieniasz PD. HIV-1 at 25. Cell. 2008 May 16; 133(4):561-5. PMID: 18485860.
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    163. Huang Y, Chen Z, Zhang W, Gurner D, Song Y, Gardiner DF, Ho DD. Design, construction, and characterization of a dual-promoter multigenic DNA vaccine directed against an HIV-1 subtype C/B' recombinant. J Acquir Immune Defic Syndr. 2008 Apr 01; 47(4):403-11. PMID: 18209683.
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    164. Chen Z, Huang Y, Zhao X, Ba L, Zhang W, Ho DD. Design, construction, and characterization of a multigenic modified vaccinia Ankara candidate vaccine against human immunodeficiency virus type 1 subtype C/B'. J Acquir Immune Defic Syndr. 2008 Apr 01; 47(4):412-21. PMID: 18209682.
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    165. Huang Y, Chen A, Li X, Chen Z, Zhang W, Song Y, Gurner D, Gardiner D, Basu S, Ho DD, Tsuji M. Enhancement of HIV DNA vaccine immunogenicity by the NKT cell ligand, alpha-galactosylceramide. Vaccine. 2008 Mar 28; 26(15):1807-16. PMID: 18329757.
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    166. Chen HY, Di Mascio M, Perelson AS, Ho DD, Zhang L. Determination of virus burst size in vivo using a single-cycle SIV in rhesus macaques. Proc Natl Acad Sci U S A. 2007 Nov 27; 104(48):19079-84. PMID: 18025463; PMCID: PMC2141911.
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    167. Ba L, Yi CE, Zhang L, Ho DD, Chen Z. Heterologous MVA-S prime Ad5-S boost regimen induces high and persistent levels of neutralizing antibody response against SARS coronavirus. Appl Microbiol Biotechnol. 2007 Oct; 76(5):1131-6. PMID: 17581748; PMCID: PMC7079952.
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    168. Janowicz DM, Tenner-Racz K, Racz P, Humphreys TL, Schnizlein-Bick C, Fortney KR, Zwickl B, Katz BP, Campbell JJ, Ho DD, Spinola SM. Experimental infection with Haemophilus ducreyi in persons who are infected with HIV does not cause local or augment systemic viral replication. J Infect Dis. 2007 May 15; 195(10):1443-51. PMID: 17436224; PMCID: PMC2571042.
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    169. Liu L, Fang Q, Deng F, Wang H, Yi CE, Ba L, Yu W, Lin RD, Li T, Hu Z, Ho DD, Zhang L, Chen Z. Natural mutations in the receptor binding domain of spike glycoprotein determine the reactivity of cross-neutralization between palm civet coronavirus and severe acute respiratory syndrome coronavirus. J Virol. 2007 May; 81(9):4694-700. PMID: 17314167; PMCID: PMC1900161.
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    170. Zhang Y, Lu L, Ba L, Liu L, Yang L, Jia M, Wang H, Fang Q, Shi Y, Yan W, Chang G, Zhang L, Ho DD, Chen Z. Dominance of HIV-1 subtype CRF01_AE in sexually acquired cases leads to a new epidemic in Yunnan province of China. PLoS Med. 2006 Nov; 3(11):e443. PMID: 17105339; PMCID: PMC1635743.
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    171. Simon V, Ho DD, Abdool Karim Q. HIV/AIDS epidemiology, pathogenesis, prevention, and treatment. Lancet. 2006 Aug 05; 368(9534):489-504. PMID: 16890836; PMCID: PMC2913538.
      Citations:    
    172. Fujio M, Wu D, Garcia-Navarro R, Ho DD, Tsuji M, Wong CH. Structure-based discovery of glycolipids for CD1d-mediated NKT cell activation: tuning the adjuvant versus immunosuppression activity. J Am Chem Soc. 2006 Jul 19; 128(28):9022-3. PMID: 16834361.
      Citations:    
    173. Woo PC, Lau SK, Tsoi HW, Chen ZW, Wong BH, Zhang L, Chan JK, Wong LP, He W, Ma C, Chan KH, Ho DD, Yuen KY. SARS coronavirus spike polypeptide DNA vaccine priming with recombinant spike polypeptide from Escherichia coli as booster induces high titer of neutralizing antibody against SARS coronavirus. Vaccine. 2005 Oct 10; 23(42):4959-68. PMID: 15993989; PMCID: PMC7115571.
      Citations:    
    174. Yi CE, Ba L, Zhang L, Ho DD, Chen Z. Single amino acid substitutions in the severe acute respiratory syndrome coronavirus spike glycoprotein determine viral entry and immunogenicity of a major neutralizing domain. J Virol. 2005 Sep; 79(18):11638-46. PMID: 16140741; PMCID: PMC1212612.
      Citations:    
    175. Gardiner DF, Huang Y, Basu S, Leung L, Song Y, Chen Z, Ho DD. Multiple-site DNA vaccination enhances immune responses in mice. Vaccine. 2006 Jan 16; 24(3):287-92. PMID: 16137804.
      Citations:    
    176. Simon V, Zennou V, Murray D, Huang Y, Ho DD, Bieniasz PD. Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification. PLoS Pathog. 2005 Sep; 1(1):e6. PMID: 16201018; PMCID: PMC1238741.
      Citations:    
    177. Di Mascio M, Percus JK, Percus OE, Markowitz M, Ho DD, Perelson AS. Duration of an intermittent episode of viremia. Bull Math Biol. 2005 Jul; 67(4):885-900. PMID: 15893558.
      Citations:    
    178. Crowe SM, Ho DD, Marriott D, Brew B, Gorry PR, Sullivan JS, Learmont J, Mills J. In vivo replication kinetics of a nef-deleted strain of HIV-1. AIDS. 2005 May 20; 19(8):842-3. PMID: 15867504.
      Citations:    
    179. Xing GW, Wu D, Poles MA, Horowitz A, Tsuji M, Ho DD, Wong CH. Synthesis and human NKT cell stimulating properties of 3-O-sulfo-alpha/beta-galactosylceramides. Bioorg Med Chem. 2005 Apr 15; 13(8):2907-16. PMID: 15781400.
      Citations:    
    180. Kinjo Y, Wu D, Kim G, Xing GW, Poles MA, Ho DD, Tsuji M, Kawahara K, Wong CH, Kronenberg M. Recognition of bacterial glycosphingolipids by natural killer T cells. Nature. 2005 Mar 24; 434(7032):520-5. PMID: 15791257.
      Citations:    
    181. Chen Z, Zhang L, Qin C, Ba L, Yi CE, Zhang F, Wei Q, He T, Yu W, Yu J, Gao H, Tu X, Gettie A, Farzan M, Yuen KY, Ho DD. Recombinant modified vaccinia virus Ankara expressing the spike glycoprotein of severe acute respiratory syndrome coronavirus induces protective neutralizing antibodies primarily targeting the receptor binding region. J Virol. 2005 Mar; 79(5):2678-88. PMID: 15708987; PMCID: PMC548443.
      Citations:    
    182. Markowitz M, Mohri H, Mehandru S, Shet A, Berry L, Kalyanaraman R, Kim A, Chung C, Jean-Pierre P, Horowitz A, La Mar M, Wrin T, Parkin N, Poles M, Petropoulos C, Mullen M, Boden D, Ho DD. Infection with multidrug resistant, dual-tropic HIV-1 and rapid progression to AIDS: a case report. Lancet. 2005 Mar 19-25; 365(9464):1031-8. PMID: 15781098.
      Citations:    
    183. Sewer A, Lagos-Quintana M, Sheridan R, Sander C, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T, Pfeffer S, Gr?sser FA. Identification of microRNAs of the herpesvirus family. Nat Methods. 2005 Apr; 2(4):269-76. PMID: 15782219.
      Citations:    
    184. Wu D, Xing GW, Poles MA, Horowitz A, Kinjo Y, Sullivan B, Bodmer-Narkevitch V, Plettenburg O, Kronenberg M, Tsuji M, Ho DD, Wong CH. Bacterial glycolipids and analogs as antigens for CD1d-restricted NKT cells. Proc Natl Acad Sci U S A. 2005 Feb 01; 102(5):1351-6. PMID: 15665086; PMCID: PMC547854.
      Citations:    
    185. Ho DD. A shot in the arm for AIDS vaccine research. PLoS Med. 2005 Feb; 2(2):e36. PMID: 15740412; PMCID: PMC544555.
      Citations:    
    186. Arron ST, Ribeiro RM, Gettie A, Bohm R, Blanchard J, Yu J, Perelson AS, Ho DD, Zhang L. Impact of thymectomy on the peripheral T cell pool in rhesus macaques before and after infection with simian immunodeficiency virus. Eur J Immunol. 2005 Jan; 35(1):46-55. PMID: 15593297.
      Citations:    
    187. Zhang L, Chen Z, Cao Y, Yu J, Li G, Yu W, Yin N, Mei S, Li L, Balfe P, He T, Ba L, Zhang F, Lin HH, Yuen MF, Lai CL, Ho DD. Molecular characterization of human immunodeficiency virus type 1 and hepatitis C virus in paid blood donors and injection drug users in china. J Virol. 2004 Dec; 78(24):13591-9. PMID: 15564470; PMCID: PMC533913.
      Citations:    
    188. Di Mascio M, Markowitz M, Louie M, Hurley A, Hogan C, Simon V, Follmann D, Ho DD, Perelson AS. Dynamics of intermittent viremia during highly active antiretroviral therapy in patients who initiate therapy during chronic versus acute and early human immunodeficiency virus type 1 infection. J Virol. 2004 Oct; 78(19):10566-73. PMID: 15367623; PMCID: PMC516378.
      Citations:    
    189. Kao RY, Tsui WH, Lee TS, Tanner JA, Watt RM, Huang JD, Hu L, Chen G, Chen Z, Zhang L, He T, Chan KH, Tse H, To AP, Ng LW, Wong BC, Tsoi HW, Yang D, Ho DD, Yuen KY. Identification of novel small-molecule inhibitors of severe acute respiratory syndrome-associated coronavirus by chemical genetics. Chem Biol. 2004 Sep; 11(9):1293-9. PMID: 15380189; PMCID: PMC7128553.
      Citations:    
    190. Kaluza GL, Gershlick AH, Park SJ, De Scheerder I, Chevalier B, Camenzind E, Goy JJ, Missault L, Reifart N, Vrints C, Urban P, Shim WH, Ho DS, Fearnot NE, Voorhees WD, Raizner AE. Comparison of neointimal formation in polymer-free paclitaxel stents versus stainless stents (from the ASPECT and ELUTES randomized clinical trials). Am J Cardiol. 2004 Jul 15; 94(2):199-201. PMID: 15246901.
      Citations: 1     Fields:    Translation:Humans
    191. Dixit NM, Markowitz M, Ho DD, Perelson AS. Estimates of intracellular delay and average drug efficacy from viral load data of HIV-infected individuals under antiretroviral therapy. Antivir Ther. 2004 Apr; 9(2):237-46. PMID: 15134186.
      Citations: 31     Fields:    Translation:HumansCells
    192. Di Mascio M, Ribeiro RM, Markowitz M, Ho DD, Perelson AS. Modeling the long-term control of viremia in HIV-1 infected patients treated with antiretroviral therapy. Math Biosci. 2004 Mar-Apr; 188:47-62. PMID: 14766093.
      Citations: 13     Fields:    Translation:HumansCells
    193. Zhang L, Lopez P, He T, Yu W, Ho DD. Retraction of an interpretation. Science. 2004 Jan 23; 303(5657):467. PMID: 14739439.
      Citations: 11     Fields:    
    194. Ramratnam B, Ribeiro R, He T, Chung C, Simon V, Vanderhoeven J, Hurley A, Zhang L, Perelson AS, Ho DD, Markowitz M. Intensification of antiretroviral therapy accelerates the decay of the HIV-1 latent reservoir and decreases, but does not eliminate, ongoing virus replication. J Acquir Immune Defic Syndr. 2004 Jan 01; 35(1):33-7. PMID: 14707789.
      Citations: 52     Fields:    Translation:HumansCellsCTClinical Trials
    195. Simon V, Ho DD. HIV-1 dynamics in vivo: implications for therapy. Nat Rev Microbiol. 2003 Dec; 1(3):181-90. PMID: 15035022.
      Citations: 78     Fields:    Translation:HumansAnimalsCells
    196. Di Mascio M, Markowitz M, Louie M, Hogan C, Hurley A, Chung C, Ho DD, Perelson AS. Viral blip dynamics during highly active antiretroviral therapy. J Virol. 2003 Nov; 77(22):12165-72. PMID: 14581553; PMCID: PMC253757.
      Citations: 34     Fields:    Translation:HumansCells
    197. Chang TL, Chang CH, Simpson DA, Xu Q, Martin PK, Lagenaur LA, Schoolnik GK, Ho DD, Hillier SL, Holodniy M, Lewicki JA, Lee PP. Inhibition of HIV infectivity by a natural human isolate of Lactobacillus jensenii engineered to express functional two-domain CD4. Proc Natl Acad Sci U S A. 2003 Sep 30; 100(20):11672-7. PMID: 12972635; PMCID: PMC208816.
      Citations: 59     Fields:    Translation:HumansCells
    198. De Boer RJ, Mohri H, Ho DD, Perelson AS. Estimating average cellular turnover from 5-bromo-2'-deoxyuridine (BrdU) measurements. Proc Biol Sci. 2003 Apr 22; 270(1517):849-58. PMID: 12737664; PMCID: PMC1691317.
      Citations: 19     Fields:    Translation:AnimalsCells
    199. Markowitz M, Louie M, Hurley A, Sun E, Di Mascio M, Perelson AS, Ho DD. A novel antiviral intervention results in more accurate assessment of human immunodeficiency virus type 1 replication dynamics and T-cell decay in vivo. J Virol. 2003 Apr; 77(8):5037-8. PMID: 12663814; PMCID: PMC152136.
      Citations: 186     Fields:    Translation:HumansCells
    200. Louie M, Hogan C, Di Mascio M, Hurley A, Simon V, Rooney J, Ruiz N, Brun S, Sun E, Perelson AS, Ho DD, Markowitz M. Determining the relative efficacy of highly active antiretroviral therapy. J Infect Dis. 2003 Mar 15; 187(6):896-900. PMID: 12660935.
      Citations: 34     Fields:    Translation:HumansCellsCTClinical Trials
    201. Percus JK, Percus OE, Markowitz M, Ho DD, Di Mascio M, Perelson AS. The distribution of viral blips observed in HIV-1 infected patients treated with combination antiretroviral therapy. Bull Math Biol. 2003 Mar; 65(2):263-77. PMID: 12675332.
      Citations: 6     Fields:    Translation:HumansCells
    202. De Boer RJ, Mohri H, Ho DD, Perelson AS. Turnover rates of B cells, T cells, and NK cells in simian immunodeficiency virus-infected and uninfected rhesus macaques. J Immunol. 2003 Mar 01; 170(5):2479-87. PMID: 12594273.
      Citations: 59     Fields:    Translation:AnimalsCells
    203. Jin X, Gao X, Ramanathan M, Deschenes GR, Nelson GW, O'Brien SJ, Goedert JJ, Ho DD, O'Brien TR, Carrington M. Human immunodeficiency virus type 1 (HIV-1)-specific CD8+-T-cell responses for groups of HIV-1-infected individuals with different HLA-B*35 genotypes. J Virol. 2002 Dec; 76(24):12603-10. PMID: 12438586; PMCID: PMC136673.
      Citations:    
    204. Ribeiro RM, Mohri H, Ho DD, Perelson AS. In vivo dynamics of T cell activation, proliferation, and death in HIV-1 infection: why are CD4+ but not CD8+ T cells depleted? Proc Natl Acad Sci U S A. 2002 Nov 26; 99(24):15572-7. PMID: 12434018; PMCID: PMC137758.
      Citations: 78     Fields:    Translation:HumansCells
    205. Ho DD, Huang Y. The HIV-1 vaccine race. Cell. 2002 Jul 26; 110(2):135-8. PMID: 12150921.
      Citations: 16     Fields:    Translation:HumansCells
    206. Ho DD. HIV and lymphocyte dynamics. Vaccine. 2002 May 06; 20(15):1933. PMID: 11983248.
      Citations: 1     Fields:    
    207. Ribeiro RM, Mohri H, Ho DD, Perelson AS. Modeling deuterated glucose labeling of T-lymphocytes. Bull Math Biol. 2002 Mar; 64(2):385-405. PMID: 11926122.
      Citations: 13     Fields:    Translation:HumansCells
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