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ROBERT BARNARD COUCH

TitleDistinguished Emeritus Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Virology & Microbiology
DivisionMolecular Virology & Microbiology
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    Other Positions
    TitleDistinguished Emeritus Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Infectious Disease


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    N01AI022672     (COUCH, ROBERT B)Jan 13, 1982 - Dec 19, 1986
    NIH/NIAID
    EVALUATE CONTROL MEASURES AGAINST INFECTIOUS DISEASES
    Role: Principal Investigator

    N01AI032685     (COUCH, ROBERT B.)Oct 26, 1982 - Oct 25, 1985
    NIH/NIAID
    OPERATION OF AN INFLUENZA RESEARCH CENTER
    Role: Principal Investigator

    N01AI062517     (COUCH, ROBERT B)Oct 26, 1985 - Dec 25, 1990
    NIH/NIAID
    OPERATION OF AN INFLUENZA RESEARCH CENTER
    Role: Principal Investigator

    N01AI072629     (COUCH, ROBERT B)Jan 20, 1987 - Dec 19, 1991
    NIH/NIAID
    EVALUATION CONTROL MEASURES AGAINST INFECTIOUS DISEASES
    Role: Principal Investigator

    N01AI015103     (COUCH, ROBERT B.)Dec 26, 1990 - Feb 29, 1996
    NIH/NIAID
    ESTABLISH AN ACUTE VIRAL RESPIRATORY DISEASE UNIT
    Role: Principal Investigator

    N01AI025135     (KEITEL, WENDY A)Dec 20, 1991 - Aug 31, 1999
    NIH/NIAID
    EVALUATION OF INFECTIOUS DISEASE CONTROL
    Role: Co-Principal Investigator

    N01AI065298     Jan 22, 1996 - Jan 31, 2003
    NIH/NIAID
    RESPIRATORY PATHOGENS RESEARCH UNIT-266965298
    Role: Co-Principal Investigator

    N01AI30039-12-0-1     (COUCH, ROBERT B)Aug 1, 2003 - Jul 31, 2010
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    N01AI30039-12-0-2     (COUCH, ROBERT B)Aug 1, 2003 - Jul 31, 2010
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    N01AI30039-12-0-3     (COUCH, ROBERT B)Aug 1, 2003 - Jul 31, 2010
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    N01AI30039-16-0-1     (COUCH, ROBERT B)Aug 1, 2003 - Oct 31, 2011
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    N01AI30039-16-0-2     (COUCH, ROBERT B)Aug 1, 2003 - Oct 31, 2011
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    N01AI30039-19-0-2     (COUCH, ROBERT B)Aug 1, 2003 - Sep 15, 2012
    NIH/NIAID
    Viral Respiratory Pathogens Research Unit
    Role: Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Algaissi A, Agrawal AS, Han S, Peng BH, Luo C, Li F, Chan TS, Couch RB, Tseng CK. Elevated Human Dipeptidyl Peptidase 4 Expression Reduces the Susceptibility of hDPP4 Transgenic Mice to Middle East Respiratory Syndrome Coronavirus Infection and Disease. J Infect Dis. 2019 Feb 15; 219(5):829-835. PMID: 30256968.
      View in: PubMed
    2. Franco LM, Bucasas KL, Wells JM, Niño D, Wang X, Zapata GE, Arden N, Renwick A, Yu P, Quarles JM, Bray MS, Couch RB, Belmont JW, Shaw CA. Correction: Integrative genomic analysis of the human immune response to influenza vaccination. Elife. 2016 Aug 30; 5. PMID: 27576045.
      View in: PubMed
    3. Agrawal AS, Tao X, Algaissi A, Garron T, Narayanan K, Peng BH, Couch RB, Tseng CT. Immunization with inactivated Middle East Respiratory Syndrome coronavirus vaccine leads to lung immunopathology on challenge with live virus. Hum Vaccin Immunother. 2016 09; 12(9):2351-6. PMID: 27269431.
      View in: PubMed
    4. Tao X, Garron T, Agrawal AS, Algaissi A, Peng BH, Wakamiya M, Chan TS, Lu L, Du L, Jiang S, Couch RB, Tseng CT. Characterization and Demonstration of the Value of a Lethal Mouse Model of Middle East Respiratory Syndrome Coronavirus Infection and Disease. J Virol. 2016 01 01; 90(1):57-67. PMID: 26446606.
      View in: PubMed
    5. Zhai Y, Franco LM, Atmar RL, Quarles JM, Arden N, Bucasas KL, Wells JM, Niño D, Wang X, Zapata GE, Shaw CA, Belmont JW, Couch RB. Host Transcriptional Response to Influenza and Other Acute Respiratory Viral Infections--A Prospective Cohort Study. PLoS Pathog. 2015 Jun; 11(6):e1004869. PMID: 26070066.
      View in: PubMed
    6. Couch RB, Bayas JM, Caso C, Mbawuike IN, López CN, Claeys C, El Idrissi M, Hervé C, Laupèze B, Oostvogels L, Moris P. Superior antigen-specific CD4+ T-cell response with AS03-adjuvantation of a trivalent influenza vaccine in a randomised trial of adults aged 65 and older. BMC Infect Dis. 2014 Jul 30; 14:425. PMID: 25078387.
      View in: PubMed
    7. Franco LM, Bucasas KL, Wells JM, Niño D, Wang X, Zapata GE, Arden N, Renwick A, Yu P, Quarles JM, Bray MS, Couch RB, Belmont JW, Shaw CA. Integrative genomic analysis of the human immune response to influenza vaccination. Elife. 2013 Jul 16; 2:e00299. PMID: 23878721.
      View in: PubMed
    8. Gulati S, Smith DF, Cummings RD, Couch RB, Griesemer SB, St George K, Webster RG, Air GM. Human H3N2 Influenza Viruses Isolated from 1968 To 2012 Show Varying Preference for Receptor Substructures with No Apparent Consequences for Disease or Spread. PLoS One. 2013; 8(6):e66325. PMID: 23805213.
      View in: PubMed
    9. Bucasas KL, Mian AI, Demmler-Harrison GJ, Caviness AC, Piedra PA, Franco LM, Shaw CA, Zhai Y, Wang X, Bray MS, Couch RB, Belmont JW. Global gene expression profiling in infants with acute respiratory syncytial virus broncholitis demonstrates systemic activation of interferon signaling networks. Pediatr Infect Dis J. 2013 Feb; 32(2):e68-76. PMID: 23190772.
      View in: PubMed
    10. Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz JM, Kiselev OI, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG. Transmission studies resume for avian flu. Science. 2013 Feb 01; 339(6119):520-1. PMID: 23345603.
      View in: PubMed
    11. Couch RB, Atmar RL, Franco LM, Quarles JM, Wells J, Arden N, Niño D, Belmont JW. Antibody correlates and predictors of immunity to naturally occurring influenza in humans and the importance of antibody to the neuraminidase. J Infect Dis. 2013 Mar 15; 207(6):974-81. PMID: 23307936.
      View in: PubMed
    12. Couch RB, Decker WK, Utama B, Atmar RL, Niño D, Feng JQ, Halpert MM, Air GM. Evaluations for in vitro correlates of immunogenicity of inactivated influenza a H5, H7 and H9 vaccines in humans. PLoS One. 2012; 7(12):e50830. PMID: 23239987.
      View in: PubMed
    13. Couch RB, Patel SM, Wade-Bowers CL, Niño D. A randomized clinical trial of an inactivated avian influenza A (H7N7) vaccine. PLoS One. 2012; 7(12):e49704. PMID: 23239968.
      View in: PubMed
    14. Couch RB, Atmar RL, Keitel WA, Quarles JM, Wells J, Arden N, Niño D. Randomized comparative study of the serum antihemagglutinin and antineuraminidase antibody responses to six licensed trivalent influenza vaccines. Vaccine. 2012 Dec 17; 31(1):190-5. PMID: 23107591.
      View in: PubMed
    15. Tseng CT, Sbrana E, Iwata-Yoshikawa N, Newman PC, Garron T, Atmar RL, Peters CJ, Couch RB. Immunization with SARS coronavirus vaccines leads to pulmonary immunopathology on challenge with the SARS virus. PLoS One. 2012; 7(4):e35421. PMID: 22536382.
      View in: PubMed
    16. Fouchier RA, García-Sastre A, Kawaoka Y, Barclay WS, Bouvier NM, Brown IH, Capua I, Chen H, Compans RW, Couch RB, Cox NJ, Doherty PC, Donis RO, Feldmann H, Guan Y, Katz J, Klenk HD, Kobinger G, Liu J, Liu X, Lowen A, Mettenleiter TC, Osterhaus AD, Palese P, Peiris JS, Perez DR, Richt JA, Schultz-Cherry S, Steel J, Subbarao K, Swayne DE, Takimoto T, Tashiro M, Taubenberger JK, Thomas PG, Tripp RA, Tumpey TM, Webby RJ, Webster RG. Pause on avian flu transmission research. Science. 2012 Jan 27; 335(6067):400-1. PMID: 22282787.
      View in: PubMed
    17. Atmar RL, Piedra PA, Patel SM, Greenberg SB, Couch RB, Glezen WP. Picornavirus, the most common respiratory virus causing infection among patients of all ages hospitalized with acute respiratory illness. J Clin Microbiol. 2012 Feb; 50(2):506-8. PMID: 22116142.
      View in: PubMed
    18. Couch RB, Atmar RL, Franco LM, Quarles JM, Niño D, Wells JM, Arden N, Cheung S, Belmont JW. Prior infections with seasonal influenza A/H1N1 virus reduced the illness severity and epidemic intensity of pandemic H1N1 influenza in healthy adults. Clin Infect Dis. 2012 Feb 01; 54(3):311-7. PMID: 22075792.
      View in: PubMed
    19. Atmar RL, Keitel WA, Quarles JM, Cate TR, Patel SM, Nino D, Wells J, Arden N, Guo K, Hill H, Couch RB. Evaluation of age-related differences in the immunogenicity of a G9 H9N2 influenza vaccine. Vaccine. 2011 Oct 19; 29(45):8066-72. PMID: 21864622.
      View in: PubMed
    20. Bucasas KL, Franco LM, Shaw CA, Bray MS, Wells JM, Niño D, Arden N, Quarles JM, Couch RB, Belmont JW. Early patterns of gene expression correlate with the humoral immune response to influenza vaccination in humans. J Infect Dis. 2011 Apr 01; 203(7):921-9. PMID: 21357945.
      View in: PubMed
    21. Couch RB, Davis BR. Has oseltamivir been shown to be effective for treatment of H5N1 influenza? J Infect Dis. 2010 Oct 15; 202(8):1149-51. PMID: 20831386.
      View in: PubMed
    22. Cate TR, Rayford Y, Niño D, Winokur P, Brady R, Belshe R, Chen W, Atmar RL, Couch RB. A high dosage influenza vaccine induced significantly more neuraminidase antibody than standard vaccine among elderly subjects. Vaccine. 2010 Feb 25; 28(9):2076-9. PMID: 20044052.
      View in: PubMed
    23. Couch RB, Atmar RL, Cate TR, Quarles JM, Keitel WA, Arden NH, Wells J, Niño D, Wyde PR. Contrasting effects of type I interferon as a mucosal adjuvant for influenza vaccine in mice and humans. Vaccine. 2009 Aug 27; 27(39):5344-8. PMID: 19607949.
      View in: PubMed
    24. Keitel WA, Atmar RL, Nino D, Cate TR, Couch RB. Increasing doses of an inactivated influenza A/H1N1 vaccine induce increasing levels of cross-reacting antibody to subsequent, antigenically different, variants. J Infect Dis. 2008 Oct 01; 198(7):1016-8. PMID: 18729777.
      View in: PubMed
    25. Couch RB. Seasonal inactivated influenza virus vaccines. Vaccine. 2008 Sep 12; 26 Suppl 4:D5-9. PMID: 18602728.
      View in: PubMed
    26. Couch RB, Winokur P, Brady R, Belshe R, Chen WH, Cate TR, Sigurdardottir B, Hoeper A, Graham IL, Edelman R, He F, Nino D, Capellan J, Ruben FL. Safety and immunogenicity of a high dosage trivalent influenza vaccine among elderly subjects. Vaccine. 2007 Nov 01; 25(44):7656-63. PMID: 17913310.
      View in: PubMed
    27. Mbawuike IN, Zhang Y, Couch RB. Control of mucosal virus infection by influenza nucleoprotein-specific CD8+ cytotoxic T lymphocytes. Respir Res. 2007 Jun 27; 8:44. PMID: 17597533.
      View in: PubMed
    28. Atmar RL, Keitel WA, Cate TR, Munoz FM, Ruben F, Couch RB. A dose-response evaluation of inactivated influenza vaccine given intranasally and intramuscularly to healthy young adults. Vaccine. 2007 Jul 20; 25(29):5367-73. PMID: 17559990.
      View in: PubMed
    29. Couch RB, Winokur P, Edwards KM, Black S, Atmar RL, Stapleton JT, Kissner JM, Shinefield H, Denny TN, Bybel MJ, Newman FK, Yan L. Reducing the dose of smallpox vaccine reduces vaccine-associated morbidity without reducing vaccination success rates or immune responses. J Infect Dis. 2007 Mar 15; 195(6):826-32. PMID: 17299712.
      View in: PubMed
    30. Feng J, Zhang M, Mozdzanowska K, Zharikova D, Hoff H, Wunner W, Couch RB, Gerhard W. Influenza A virus infection engenders a poor antibody response against the ectodomain of matrix protein 2. Virol J. 2006 Dec 06; 3:102. PMID: 17150104.
      View in: PubMed
    31. Safdar A, Rodriguez MA, Fayad LE, Rodriguez GH, Pro B, Wang M, Romaguera JE, Goy AH, Hagemeister FB, McLaughlin P, Bodey GP, Kwak LW, Raad II, Couch RB. Dose-related safety and immunogenicity of baculovirus-expressed trivalent influenza vaccine: a double-blind, controlled trial in adult patients with non-Hodgkin B cell lymphoma. J Infect Dis. 2006 Nov 15; 194(10):1394-7. PMID: 17054068.
      View in: PubMed
    32. Atmar RL, Keitel WA, Patel SM, Katz JM, She D, El Sahly H, Pompey J, Cate TR, Couch RB. Safety and immunogenicity of nonadjuvanted and MF59-adjuvanted influenza A/H9N2 vaccine preparations. Clin Infect Dis. 2006 Nov 01; 43(9):1135-42. PMID: 17029131.
      View in: PubMed
    33. Keitel WA, Atmar RL, Cate TR, Petersen NJ, Greenberg SB, Ruben F, Couch RB. Safety of high doses of influenza vaccine and effect on antibody responses in elderly persons. Arch Intern Med. 2006 May 22; 166(10):1121-7. PMID: 16717175.
      View in: PubMed
    34. Treanor JJ, Schiff GM, Couch RB, Cate TR, Brady RC, Hay CM, Wolff M, She D, Cox MM. Dose-related safety and immunogenicity of a trivalent baculovirus-expressed influenza-virus hemagglutinin vaccine in elderly adults. J Infect Dis. 2006 May 01; 193(9):1223-8. PMID: 16586358.
      View in: PubMed
    35. Woo PC, Lau SK, Wong BH, Chan KH, Hui WT, Kwan GS, Peiris JS, Couch RB, Yuen KY. False-positive results in a recombinant severe acute respiratory syndrome-associated coronavirus (SARS-CoV) nucleocapsid enzyme-linked immunosorbent assay due to HCoV-OC43 and HCoV-229E rectified by Western blotting with recombinant SARS-CoV spike polypeptide. J Clin Microbiol. 2004 Dec; 42(12):5885-8. PMID: 15583332.
      View in: PubMed
    36. Couch RB. Nasal vaccination, Escherichia coli enterotoxin, and Bell's palsy. N Engl J Med. 2004 Feb 26; 350(9):860-1. PMID: 14985482.
      View in: PubMed
    37. Belshe RB, Newman FK, Frey SE, Couch RB, Treanor JJ, Tacket CO, Yan L. Dose-dependent neutralizing-antibody responses to vaccinia. J Infect Dis. 2004 Feb 01; 189(3):493-7. PMID: 14745707.
      View in: PubMed
    38. Glezen WP, Couch RB. Estimating deaths due to influenza and respiratory syncytial virus. JAMA. 2003 May 21; 289(19):2500; author reply 2500-2. PMID: 12759318.
      View in: PubMed
    39. Belshe RB, Couch RB, Glezen WP, Treanor JT. Live attenuated intranasal influenza vaccine. Vaccine. 2002 Oct 04; 20(29-30):3429-30. PMID: 12297386.
      View in: PubMed
    40. Frey SE, Couch RB, Tacket CO, Treanor JJ, Wolff M, Newman FK, Atmar RL, Edelman R, Nolan CM, Belshe RB. Clinical responses to undiluted and diluted smallpox vaccine. N Engl J Med. 2002 Apr 25; 346(17):1265-74. PMID: 11923490.
      View in: PubMed
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