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NASSER M LAKKIS

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
DivisionMedicine-Cardiology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Khan MR, Kayani WT, Ahmad W, Manan M, Hira RS, Hamzeh I, Jneid H, Virani SS, Kleiman N, Lakkis N, Alam M. Effect of increasing age on percutaneous coronary intervention vs coronary artery bypass grafting in older adults with unprotected left main coronary artery disease: A meta-analysis and meta-regression. Clin Cardiol. 2019 Sep 05. PMID: 31486094.
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    2. Siebert VR, Borgaonkar S, Jia X, Nguyen HL, Birnbaum Y, Lakkis NM, Alam M. Meta-analysis Comparing Multivessel Versus Culprit Coronary Arterial Revascularization for Patients With Non-ST-Segment Elevation Acute Coronary Syndromes. Am J Cardiol. 2019 Aug 29. PMID: 31575424.
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    3. Pei DT, Liu J, Yaqoob M, Ahmad W, Bandeali SS, Hamzeh IR, Virani SS, Hira RS, Lakkis NM, Alam M. Meta-Analysis of Catheter Directed Ultrasound-Assisted Thrombolysis in Pulmonary Embolism. Am J Cardiol. 2019 Nov 01; 124(9):1470-1477. PMID: 31492420.
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    4. Laeeq R, Berman JS, Khalid U, Lakkis NM, Tabbaa R. Reversible Cerebral Vasoconstriction Syndrome Associated with Coronary Artery Vasospasm. Tex Heart Inst J. 2019 Apr; 46(2):139-142. PMID: 31236082.
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    5. Maini R, Lim J, Liu J, Birnbaum I, Mirza F, Lakkis N, Hamzeh I. A Double Whammy: Severe Aortic Stenosis and Cocaine Overwhelm the Mitral Valve. Methodist Debakey Cardiovasc J. 2018 Jan-Mar; 14(1):63-65. PMID: 29623174.
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    6. Khalid U, Rojas F, Lakkis N. Flecainide-Induced Left Ventricular Dysfunction: Fact or Fiction? Cardiovasc Toxicol. 2017 10; 17(4):494-495. PMID: 28534245.
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    7. Khan MR, Kayani WT, Ahmad W, Hira RS, Virani SS, Hamzeh I, Jneid H, Lakkis N, Alam M. Meta-Analysis of Comparison of 5-Year Outcomes of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting in Patients With Unprotected Left Main Coronary Artery in the Era of Drug-eluting Stents. Am J Cardiol. 2017 Nov 01; 120(9):1514-1520. PMID: 28886851.
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    8. Singh M, Khalid U, Lakkis N, Tabbaa R. Inflammatory Pseudotumor Originating from the Right Ventricular Outflow Tract. Case Rep Cardiol. 2016; 2016:6527479. PMID: 28003915.
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    9. Kanahara S, El-Refai M, Lakkis N, Tabbaa R. Acute ascending aortic dissection after MDMA/ecstasy use: A case report. Hellenic J Cardiol. 2016 Sep - Oct; 57(5):351-354. PMID: 28314643.
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    10. Hoang V, Grounds J, Pham D, Virani S, Hamzeh I, Qureshi AM, Lakkis N, Alam M. The Role of Intracoronary Plaque Imaging with Intravascular Ultrasound, Optical Coherence Tomography, and Near-Infrared Spectroscopy in Patients with Coronary Artery Disease. Curr Atheroscler Rep. 2016 09; 18(9):57. PMID: 27485540.
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    11. Hoang V, Addison D, Lakkis N, Tabbaa R. ANA-Negative Lupus Presenting with Heart Failure and Severe Valvular Dysfunction: Case Report and Review of the Literature. Methodist Debakey Cardiovasc J. 2015 Jul-Sep; 11(3):186-8. PMID: 26634028.
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    12. Murray T, Yang EY, Brunner G, Kumar A, Lakkis N, Misra A, Virani SS, Hartley CJ, Morrisett JD, Ballantyne CM, Nambi V. Postprandial effects on arterial stiffness parameters in healthy young adults. Vasc Med. 2015 Dec; 20(6):501-8. PMID: 26060082.
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    13. Koerner MM, Alam M, El-Banayosy A, Misra A, Wall MJ, Zeriouh M, Lakkis NM, Ghodsizad A. A case of biventricular failure after pericardial window for large pericardial effusion. Heart Surg Forum. 2015 Feb 27; 18(1):E36-7. PMID: 25881224.
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    14. Maini R, Dadu RT, Addison D, Cunningham L, Hamzeh I, Wall M, Lakkis N, Tabbaa R. Isolated perforation of left coronary cusp after blunt chest trauma. Case Rep Cardiol. 2015; 2015:235629. PMID: 25802765.
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    15. Khalid U, Hirudayaraj P, Lakkis N, Tabbaa R. Left atrial thrombus mimicking a myxoma in a patient with systemic lupus erythematosus. Hellenic J Cardiol. 2014 Mar-Apr; 55(2):167-70. PMID: 24681796.
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    16. Huang HD, Garcia M, Alam M, Misra A, Lakkis N, Tabbaa R. Post-operative intrapericardial hematoma presenting as isolated right atrial tamponade. J Cardiol Cases. 2014 Feb; 9(2):48-49. PMID: 30534293.
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    17. Yang EY, Brunner G, Dokainish H, Hartley CJ, Taffet G, Lakkis N, Taylor AA, Misra A, McCulloch ML, Morrisett JD, Virani SS, Ballantyne CM, Nagueh SF, Nambi V. Application of speckle-tracking in the evaluation of carotid artery function in subjects with hypertension and diabetes. J Am Soc Echocardiogr. 2013 Aug; 26(8):901-909.e1. PMID: 23759168.
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    18. Alam M, Virani SS, Shahzad SA, Siddiqui S, Siddiqui KH, Mumtaz SA, Kleiman NS, Coselli JS, Lakkis NM, Jneid H. Comparison by meta-analysis of percutaneous coronary intervention versus coronary artery bypass grafting in patients with a mean age of =70 years. Am J Cardiol. 2013 Sep 01; 112(5):615-22. PMID: 23726179.
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    19. Alam M, Bandeali SJ, Kayani WT, Ahmad W, Shahzad SA, Jneid H, Birnbaum Y, Kleiman NS, Coselli JS, Ballantyne CM, Lakkis N, Virani SS. Comparison by meta-analysis of mortality after isolated coronary artery bypass grafting in women versus men. Am J Cardiol. 2013 Aug 01; 112(3):309-17. PMID: 23642381.
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    20. Alam M, Zhang L, Stampehl M, Lakkis N, Dokainish H. Usefulness of speckle tracking echocardiography in hypertensive crisis and the effect of medical treatment. Am J Cardiol. 2013 Jul 15; 112(2):260-5. PMID: 23597771.
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    21. Posligua W, Zarrin-Khameh N, Tsai P, Lakkis N. Fibrosing mediastinitis causing ostial coronary artery compression in a young woman. J Am Coll Cardiol. 2012 Dec 25; 60(25):2693. PMID: 23257305.
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    22. Alam M, Bandeali SJ, Virani SS, Jneid HM, Shahzad SA, Ramanathan KB, Kar B, Kleiman NS, Lakkis N. Clinical outcomes of percutaneous interventions in saphenous vein grafts using drug-eluting stents compared to bare-metal stents: a comprehensive meta-analysisof all randomized clinical trials. Clin Cardiol. 2012 May; 35(5):291-6. PMID: 22488047.
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    23. Alam M, Bandeali SJ, Shahzad SA, Lakkis N. Real-life global survey evaluating patients with atrial fibrillation (REALISE-AF): results of an international observational registry. Expert Rev Cardiovasc Ther. 2012 Mar; 10(3):283-91. PMID: 22390799.
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    24. Basra SS, Tsai P, Lakkis NM. Safety and efficacy of antiplatelet and antithrombotic therapy in acute coronary syndrome patients with chronic kidney disease. J Am Coll Cardiol. 2011 Nov 22; 58(22):2263-9. PMID: 22093501.
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    25. Yang EY, Dokainish H, Virani SS, Misra A, Pritchett AM, Lakkis N, Brunner G, Bobek J, McCulloch ML, Hartley CJ, Ballantyne CM, Nagueh SF, Nambi V. Segmental analysis of carotid arterial strain using speckle-tracking. J Am Soc Echocardiogr. 2011 Nov; 24(11):1276-1284.e5. PMID: 21907541.
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    26. Dokainish H, Nguyen JS, Bobek J, Goswami R, Lakkis NM. Assessment of the American Society of Echocardiography-European Association of Echocardiography guidelines for diastolic function in patients with depressed ejection fraction: an echocardiographic and invasive haemodynamic study. Eur J Echocardiogr. 2011 Nov; 12(11):857-64. PMID: 21890470.
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    27. Addison D, Brammer J, Gupta S, Lakkis N. Postpartum spontaneous coronary dissection presenting with ventricular fibrillation. J Cardiol Cases. 2011 Feb; 3(1):e17-e21. PMID: 30532826.
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    28. Nguyen JS, Lakkis NM, Bobek J, Goswami R, Dokainish H. Systolic and diastolic myocardial mechanics in patients with cardiac disease and preserved ejection fraction: impact of left ventricular filling pressure. J Am Soc Echocardiogr. 2010 Dec; 23(12):1273-80. PMID: 20970305.
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    29. Patel P, Dokainish H, Tsai P, Lakkis N. Update on the association of inflammation and atrial fibrillation. J Cardiovasc Electrophysiol. 2010 Sep; 21(9):1064-70. PMID: 20455973.
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    30. Dokainish H, Nguyen J, Sengupta R, Pillai M, Alam M, Bobek J, Lakkis N. New, simple echocardiographic indexes for the estimation of filling pressure in patients with cardiac disease and preserved left ventricular ejection fraction. Echocardiography. 2010 Sep; 27(8):946-53. PMID: 20849482.
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    31. Shiue HC, Divakaran VG, Lakkis NM. A case of Brugada syndrome presenting with incessant polymorphic ventricular tachycardia. Clin Cardiol. 2010 Mar; 33(3):E33-5. PMID: 20127895.
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    32. Dokainish H, Nguyen JS, Sengupta R, Pillai M, Alam M, Bobek J, Lakkis N. Do additional echocardiographic variables increase the accuracy of E/e' for predicting left ventricular filling pressure in normal ejection fraction? An echocardiographic and invasive hemodynamic study. J Am Soc Echocardiogr. 2010 Feb; 23(2):156-61. PMID: 20152696.
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    33. Aslam F, Alam M, Lakkis NM. Hepatitis C and carotid atherosclerosis: a retrospective analysis. Atherosclerosis. 2010 Apr; 209(2):340-3. PMID: 19883912.
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    34. Alam M, Thaver GH, Misra A, Lakkis N. Persistent left superior vena cava: an incidental finding. J Am Coll Cardiol. 2009 Mar 31; 53(13):1159. PMID: 19324262.
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    35. Alam M, Dokainish H, Lakkis NM. Hypertrophic obstructive cardiomyopathy-alcohol septal ablation vs. myectomy: a meta-analysis. Eur Heart J. 2009 May; 30(9):1080-7. PMID: 19233857.
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    36. Alam M, Gonzalez R, Delarosa A, Bobek J, Dokainish H, Lakkis N. In vitro inhibition of platelet aggregation in response to increasing concentrations of tirofiban in patients with significant renal insufficiency. Am Heart Hosp J. 2009; 7(1):17-20. PMID: 19742428.
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    37. Abuzahra M, Pillai M, Caldera A, Hartley WB, Gonzalez R, Bobek J, Dokainish H, Lakkis N. Comparison of higher clopidogrel loading and maintenance dose to standard dose on platelet function and outcomes after percutaneous coronary intervention using drug-eluting stents. Am J Cardiol. 2008 Aug 15; 102(4):401-3. PMID: 18678295.
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    38. Dokainish H, Sengupta R, Pillai M, Bobek J, Lakkis N. Assessment of left ventricular systolic function using echocardiography in patients with preserved ejection fraction and elevated diastolic pressures. Am J Cardiol. 2008 Jun 15; 101(12):1766-71. PMID: 18549856.
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    39. Dokainish H, Sengupta R, Pillai M, Bobek J, Lakkis N. Usefulness of new diastolic strain and strain rate indexes for the estimation of left ventricular filling pressure. Am J Cardiol. 2008 May 15; 101(10):1504-9. PMID: 18471466.
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    40. Plana JC, Mikati IA, Dokainish H, Lakkis N, Abukhalil J, Davis R, Hetzell BC, Zoghbi WA. A randomized cross-over study for evaluation of the effect of image optimization with contrast on the diagnostic accuracy of dobutamine echocardiography in coronary artery disease The OPTIMIZE Trial. JACC Cardiovasc Imaging. 2008 Mar; 1(2):145-52. PMID: 19356420.
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    41. Ferguson AD, Dokainish H, Lakkis N. Aspirin and clopidogrel response variability: review of the published literature. Tex Heart Inst J. 2008; 35(3):313-20. PMID: 18941611.
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    42. Medina HM, Vazquez J, Pritchett A, Lakkis N, Dokainish H. Comprehensive imaging including three-dimensional echocardiography of an infected, ruptured sinus of valsalva aneurysm. Echocardiography. 2007 Nov; 24(10):1096-8. PMID: 18001366.
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    43. Dokainish H, Gonzalez R, Hartley WB, Caldera A, Koshy S, Sengupta R, Lakkis NM. Usefulness of B-type natriuretic peptide levels to predict left ventricular filling pressures in patients with body mass index >35, 31 to 35, and < or =30 kg/m2. Am J Cardiol. 2007 Oct 01; 100(7):1166-71. PMID: 17884382.
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    44. Dokainish H, Sengupta R, Patel R, Lakkis N. Usefulness of right ventricular tissue Doppler imaging to predict outcome in left ventricular heart failure independent of left ventricular diastolic function. Am J Cardiol. 2007 Apr 01; 99(7):961-5. PMID: 17398192.
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    45. Sarkiss MG, Yusuf SW, Warneke CL, Botz G, Lakkis N, Hirch-Ginsburg C, Champion JC, Swafford J, Shaw AD, Lenihan DJ, Durand JB. Impact of aspirin therapy in cancer patients with thrombocytopenia and acute coronary syndromes. Cancer. 2007 Feb 01; 109(3):621-7. PMID: 17167763.
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    46. Dokainish H, Lakkis N. Can alcohol septal ablation normalize systolic function in HOCM? Eur Heart J. 2006 Dec; 27(23):2746-7. PMID: 17098758.
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    47. Habbu A, Lakkis NM, Dokainish H. The obesity paradox: fact or fiction? Am J Cardiol. 2006 Oct 01; 98(7):944-8. PMID: 16996880.
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    48. Alam M, Dokainish H, Lakkis N. Alcohol septal ablation for hypertrophic obstructive cardiomyopathy: a systematic review of published studies. J Interv Cardiol. 2006 Aug; 19(4):319-27. PMID: 16881978.
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    49. Dokainish H, Lakkis N. Alcohol relaxes the stiff heart. Eur Heart J. 2006 Aug; 27(15):1769-70. PMID: 16801326.
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    50. Gibson CM, Morrow DA, Murphy SA, Palabrica TM, Jennings LK, Stone PH, Lui HH, Bulle T, Lakkis N, Kovach R, Cohen DJ, Fish P, McCabe CH, Braunwald E. A randomized trial to evaluate the relative protection against post-percutaneous coronary intervention microvascular dysfunction, ischemia, and inflammation among antiplatelet and antithrombotic agents: the PROTECT-TIMI-30 trial. J Am Coll Cardiol. 2006 Jun 20; 47(12):2364-73. PMID: 16781360.
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    51. Kirtane AJ, Piazza G, Murphy SA, Budiu D, Morrow DA, Cohen DJ, Peterson E, Lakkis N, Herrmann HC, Palabrica TM, Gibson CM. Correlates of bleeding events among moderate- to high-risk patients undergoing percutaneous coronary intervention and treated with eptifibatide: observations from the PROTECT-TIMI-30 trial. J Am Coll Cardiol. 2006 Jun 20; 47(12):2374-9. PMID: 16781361.
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    52. Gibson CM, Karmpaliotis D, Kosmidou I, Murphy SA, Kirtane AJ, Budiu D, Ray KK, Herrmann HC, Lakkis N, Kovach R, French W, Blankenship J, Lui HH, Palabrica T, Jennings LK, Cohen DJ, Morrow DA. Comparison of effects of bare metal versus drug-eluting stent implantation on biomarker levels following percutaneous coronary intervention for non-ST-elevation acute coronary syndrome. Am J Cardiol. 2006 May 15; 97(10):1473-7. PMID: 16679086.
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    53. Dokainish H, Zoghbi WA, Ambriz E, Lakkis NM, Quinones MA, Nagueh SF. Comparative cost-effectiveness of B-type natriuretic peptide and echocardiography for predicting outcome in patients with congestive heart failure. Am J Cardiol. 2006 Feb 01; 97(3):400-3. PMID: 16442404.
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    54. Patel P, Patel P, Gonzalez R, Gonzales R, Dokainish H, Lakkis N. Impact of adenosine diphosphate and calcium chelation on platelet aggregation testing in patients receiving clopidogrel therapy. J Am Coll Cardiol. 2006 Jan 17; 47(2):464-5. PMID: 16412878.
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    55. Trukhacheva E, Scharff M, Gardner M, Lakkis N. Massive pulmonary embolism in pregnancy treated with tissue plasminogen activator. Obstet Gynecol. 2005 Nov; 106(5 Pt 2):1156-8. PMID: 16260552.
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    56. Nambi V, Buergler JM, Lakkis NM, Franklin J, Spencer WH, Nagueh SF. Effectiveness of percutaneous intervention for patients with obstructive hypertrophic cardiomyopathy and coronary artery disease. Am J Cardiol. 2005 Aug 15; 96(4):580-1. PMID: 16098315.
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    57. Dokainish H, Zoghbi WA, Lakkis NM, Ambriz E, Patel R, Quinones MA, Nagueh SF. Incremental predictive power of B-type natriuretic peptide and tissue Doppler echocardiography in the prognosis of patients with congestive heart failure. J Am Coll Cardiol. 2005 Apr 19; 45(8):1223-6. PMID: 15837253.
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    58. Dokainish H, Pillai M, Murphy SA, DiBattiste PM, Schweiger MJ, Lotfi A, Morrow DA, Cannon CP, Braunwald E, Lakkis N. Prognostic implications of elevated troponin in patients with suspected acute coronary syndrome but no critical epicardial coronary disease: a TACTICS-TIMI-18 substudy. J Am Coll Cardiol. 2005 Jan 04; 45(1):19-24. PMID: 15629367.
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    59. Lakkis N, Dokainish H, Abuzahra M, Tsyboulev V, Jorgensen J, De Leon AP, Saleem A. Reticulated platelets in acute coronary syndrome: a marker of platelet activity. J Am Coll Cardiol. 2004 Nov 16; 44(10):2091-3. PMID: 15542299.
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    60. Fox KA, Mehta SR, Peters R, Zhao F, Lakkis N, Gersh BJ, Yusuf S. Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) Trial. Circulation. 2004 Sep 07; 110(10):1202-8. PMID: 15313956.
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    61. Chang SM, Yazbek N, Lakkis NM. Use of statins prior to percutaneous coronary intervention reduces myonecrosis and improves clinical outcome. Catheter Cardiovasc Interv. 2004 Jun; 62(2):193-7. PMID: 15170709.
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    62. Dokainish H, Zoghbi WA, Lakkis NM, Al-Bakshy F, Dhir M, Quinones MA, Nagueh SF. Optimal noninvasive assessment of left ventricular filling pressures: a comparison of tissue Doppler echocardiography and B-type natriuretic peptide in patients with pulmonary artery catheters. Circulation. 2004 May 25; 109(20):2432-9. PMID: 15123522.
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    63. Dokainish H, Zoghbi WA, Lakkis NM, Quinones MA, Nagueh SF. Comparative accuracy of B-type natriuretic peptide and tissue Doppler echocardiography in the diagnosis of congestive heart failure. Am J Cardiol. 2004 May 01; 93(9):1130-5. PMID: 15110205.
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    64. Chang SM, Lakkis NM, Franklin J, Spencer WH, Nagueh SF. Predictors of outcome after alcohol septal ablation therapy in patients with hypertrophic obstructive cardiomyopathy. Circulation. 2004 Feb 24; 109(7):824-7. PMID: 14967729.
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    65. Nagueh SF, Lakkis NM, Middleton KJ, Franklin J, Spencer WH. Images in cardiovascular medicine. Avoiding papillary muscle infarction with myocardial contrast echocardiographic guidance of nonsurgical septal reduction therapy for hypertrophic obstructive cardiomyopathy. Circulation. 2004 Feb 10; 109(5):e27-8. PMID: 14769690.
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    66. Chang Sm, Sekandarzad MW, Jiang S, Nagueh S, Spencer W, Lakkis N. Impact of infarct size on clinical and echocardiographic outcome in patients undergoing nonsurgical septal reduction therapy. Am Heart J. 2003 Dec; 146(6):1112-4. PMID: 14661008.
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    67. Chang SM, Nagueh SF, Spencer WH, Lakkis NM. Complete heart block: determinants and clinical impact in patients with hypertrophic obstructive cardiomyopathy undergoing nonsurgical septal reduction therapy. J Am Coll Cardiol. 2003 Jul 16; 42(2):296-300. PMID: 12875767.
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    68. Casserly IP, Topol EJ, Jia G, Lange RA, Hamm C, Meier B, DiBattiste PM, Lakkis N, Chew DP, Stone GW, Cohen DJ, Moliterno DJ. Effect of abciximab versus tirofiban on activated clotting time during percutaneous intervention and its relation to clinical outcomes--observations from the TARGET trial. Am J Cardiol. 2003 Jul 15; 92(2):125-9. PMID: 12860211.
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    69. Schneider DJ, Herrmann HC, Lakkis N, Aguirre F, Lo MW, Yin KC, Aggarwal A, Kabbani SS, DiBattiste PM. Increased concentrations of tirofiban in blood and their correlation with inhibition of platelet aggregation after greater bolus doses of tirofiban. Am J Cardiol. 2003 Feb 01; 91(3):334-6. PMID: 12565092.
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    70. Schneider DJ, Herrmann HC, Lakkis N, Aguirre F, Wan Y, Aggarwal A, Kabbani SS, DiBattiste PM. Enhanced early inhibition of platelet aggregation with an increased bolus of tirofiban. Am J Cardiol. 2002 Dec 15; 90(12):1421-3. PMID: 12480064.
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    71. Lakkis N, Tsyboulev V, Gibson CM, Murphy SA, Weintraub WS, DiBattiste PM, Cannon CP. Outcome of patients with acute coronary syndrome admitted to hospitals with or without onsite cardiac catheterization laboratory: a TACTICS-TIMI 18 substudy. Crit Pathw Cardiol. 2002 Dec; 1(4):232-7. PMID: 18340309.
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    72. Keng FY, Chang SM, Cwajg E, He ZX, Lakkis NM, Nagueh SF, Spencer WH, Verani MS. Gated SPECT in patients with hypertrophic obstructive cardiomyopathy undergoing transcoronary ethanol septal ablation. J Nucl Cardiol. 2002 Nov-Dec; 9(6):594-600. PMID: 12466783.
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    73. Park TH, Lakkis NM, Middleton KJ, Franklin J, Zoghbi WA, QuiƱones MA, Spencer WH, Nagueh SF. Acute effect of nonsurgical septal reduction therapy on regional left ventricular asynchrony in patients with hypertrophic obstructive cardiomyopathy. Circulation. 2002 Jul 23; 106(4):412-5. PMID: 12135938.
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