TitleClinical Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Obstetrics & Gynecology
Address2 Chelsea Blvd
Houston, TX 77006
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Peterson ER, Sajjakulnukit P, Scott AJ, Heaslip C, Andren A, Wilder-Romans K, Zhou W, Palavalasa S, Korimerla N, Lin A, O'Brien A, Kothari A, Zhao Z, Zhang L, Morgan MA, Venneti S, Koschmann C, Jabado N, Lyssiotis CA, Castro MG, Wahl DR. Purine salvage promotes treatment resistance in H3K27M-mutant diffuse midline glioma. Cancer Metab. 2024 Apr 09; 12(1):11. PMID: 38594734; PMCID: PMC11003124.
    2. Zhang Q, Jiang L, Wang W, Huber AK, Valvo VM, Jungles KM, Holcomb EA, Pearson AN, The S, Wang Z, Parsels LA, Parsels JD, Wahl DR, Rao A, Sahai V, Lawrence TS, Green MD, Morgan MA, Zhang Q, Jiang L, Huber AK, Valvo VM, Jungles KM, Holcomb EA, Pearson AN, The S, Wang Z, Parsels LA, Parsels JD, Wahl DR, Rao A, Sahai V, Lawrence TS, Green MD, Morgan MA. Potentiating the radiation-induced type I interferon antitumoral immune response by ATM inhibition in pancreatic cancer. JCI Insight. 2024 Feb 20; 9(6). PMID: 38376927.
      Citations:    Fields:    Translation:Animals
    3. Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O'Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Gyorffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR, Zhou W, Zhao Z, Lin A, Yang JZ, Xu J, Wilder-Romans K, Yang A, Li J, Solanki S, Speth JM, Walker N, Scott AJ, Wang L, Wen B, Andren A, Zhang L, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Ullrich A, Liang J, Jacobson J, Palavalasa S, O'Brien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Gyorffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. GTP Signaling Links Metabolism, DNA Repair, and Responses to Genotoxic Stress. Cancer Discov. 2024 01 12; 14(1):158-175. PMID: 37902550; PMCID: PMC10872631.
      Citations:    Fields:    Translation:HumansAnimalsCells
    4. Koschmann C, Al-Holou WN, Alonso MM, Anastas J, Bandopadhayay P, Barron T, Becher O, Cartaxo R, Castro MG, Chung C, Clausen M, Dang D, Doherty R, Duchatel R, Dun M, Filbin M, Franson A, Galban S, Garcia Moure M, Garton H, Gowda P, Marques JG, Hawkins C, Heath A, Hulleman E, Ji S, Jones C, Kilburn L, Kline C, Koldobskiy MA, Lim D, Lowenstein PR, Lu QR, Lum J, Mack S, Magge S, Marini B, Martin D, Marupudi N, Messinger D, Mody R, Morgan M, Mota M, Muraszko K, Mueller S, Natarajan SK, Nazarian J, Niculcea M, Nuechterlein N, Okada H, Opipari V, Pai MP, Pal S, Peterson E, Phoenix T, Prensner JR, Pun M, Raju GP, Reitman ZJ, Resnick A, Rogawski D, Saratsis A, Sbergio SG, Souweidane M, Stafford JM, Tzaridis T, Venkataraman S, Vittorio O, Wadden J, Wahl D, Wechsler-Reya RJ, Yadav VN, Zhang X, Zhang Q, Venneti S. A road map for the treatment of pediatric diffuse midline glioma. Cancer Cell. 2024 01 08; 42(1):1-5. PMID: 38039965.
      Citations: 1     Fields:    Translation:Humans
    5. Peterson ER, Sajjakulnukit P, Scott AJ, Heaslip C, Andren A, Wilder-Romans K, Zhou W, Palavalasa S, Korimerla N, Lin A, Obrien A, Kothari A, Zhao Z, Zhang L, Morgan MA, Venneti S, Koschmann C, Jabado N, Lyssiotis CA, Castro MG, Wahl DR. Adaptive rewiring of purine metabolism promotes treatment resistance in H3K27M-mutant diffuse midline glioma. Res Sq. 2023 Sep 11. PMID: 37790517; PMCID: PMC10543500.
    6. Valvo V, Vitale E, Tigano M, Evans R, Morgan MA, Zhang Q. Editorial: Targeting DNA damage response to enhance antitumor innate immunity in radiotherapy. Front Oncol. 2023; 13:1257622. PMID: 37560464; PMCID: PMC10408123.
    7. Zhou W, Zhao Z, Lin A, Yang J, Xu J, Kari WR, Yang A, Li J, Solanki S, Speth J, Walker N, Scott AJ, Kothari AU, Yao Y, Peterson ER, Korimerla N, Werner CK, Liang J, Jacobson J, Palavalasa S, Obrien AM, Elaimy AL, Ferris SP, Zhao SG, Sarkaria JN, Gyorffy B, Zhang S, Al-Holou WN, Umemura Y, Morgan MA, Lawrence TS, Lyssiotis CA, Peters-Golden M, Shah YM, Wahl DR. GTP signaling links metabolism, DNA repair, and responses to genotoxic stress. bioRxiv. 2023 Apr 13. PMID: 37090571; PMCID: PMC10120670.
    8. Parsels LA, Wahl DR, Koschmann C, Morgan MA, Zhang Q. Developing H3K27M mutant selective radiosensitization strategies in diffuse intrinsic pontine glioma. Neoplasia. 2023 03; 37:100881. PMID: 36724689; PMCID: PMC9918797.
      Citations: 1     Fields:    Translation:Humans
    9. Nguyen CB, Su CT, Morgan M, Alva AS. Case report: Immune-mediated meibomian gland dysfunction following pembrolizumab therapy for advanced urothelial carcinoma. Front Oncol. 2022; 12:1000023. PMID: 36276085; PMCID: PMC9582237.
    10. Wang W, McMillan MT, Zhao X, Wang Z, Jiang L, Karnak D, Lima F, Parsels JD, Parsels LA, Lawrence TS, Frankel TL, Morgan MA, Green MD, Zhang Q. DNA-PK Inhibition and Radiation Promote Antitumoral Immunity through RNA Polymerase III in Pancreatic Cancer. Mol Cancer Res. 2022 07 06; 20(7):1137-1150. PMID: 35348737; PMCID: PMC9262824.
      Citations:    Fields:    Translation:Humans
    11. Qin T, Mullan B, Ravindran R, Messinger D, Siada R, Cummings JR, Harris M, Muruganand A, Pyaram K, Miklja Z, Reiber M, Garcia T, Tran D, Danussi C, Brosnan-Cashman J, Pratt D, Zhao X, Rehemtulla A, Sartor MA, Venneti S, Meeker AK, Huse JT, Morgan MA, Lowenstein PR, Castro MG, Yadav VN, Koschmann C. ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization. Cell Rep. 2022 01 11; 38(2):110216. PMID: 35021084; PMCID: PMC8759735.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    12. Parsels LA, Zhang Q, Karnak D, Parsels JD, Lam K, Willers H, Green MD, Rehemtulla A, Lawrence TS, Morgan MA. Translation of DNA Damage Response Inhibitors as Chemoradiation Sensitizers From the Laboratory to the Clinic. Int J Radiat Oncol Biol Phys. 2021 12 01; 111(5):e38-e53. PMID: 34348175; PMCID: PMC8602768.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Willers H, Pan X, Egan R, Greninger P, Rosenkranz A, Kung J, Liss AS, Parsels LA, Morgan MA, Lawrence TS, Lin SH, Hong TS, Yeap BY, Wirth LJ, Hata AN, Ott CJ, Benes CH, Borgeaud N, Korovina I, Koi L, Baumann M, Krause M. Screening and Validation of Molecular Targeted Radiosensitizers. Int J Radiat Oncol Biol Phys. 2021 12 01; 111(5):e63-e74. PMID: 34343607; PMCID: PMC8602724.
      Citations: 2     Fields:    Translation:Humans
    14. Zhao K, Zhang Q, Flanagan SA, Lang X, Jiang L, Parsels LA, Parsels JD, Zou W, Lawrence TS, Green MD, Morgan MA, Buisson R. Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-Dependent Manner. Mol Cancer Res. 2021 09; 19(9):1571-1582. PMID: 34045311; PMCID: PMC8419025.
      Citations:    Fields:    Translation:HumansCells
    15. Yu J, Green MD, Li S, Sun Y, Journey SN, Choi JE, Rizvi SM, Qin A, Waninger JJ, Lang X, Chopra Z, El Naqa I, Zhou J, Bian Y, Jiang L, Tezel A, Skvarce J, Achar RK, Sitto M, Rosen BS, Su F, Narayanan SP, Cao X, Wei S, Szeliga W, Vatan L, Mayo C, Morgan MA, Schonewolf CA, Cuneo K, Kryczek I, Ma VT, Lao CD, Lawrence TS, Ramnath N, Wen F, Chinnaiyan AM, Cieslik M, Alva A, Zou W. Liver metastasis restrains immunotherapy efficacy via macrophage-mediated T cell elimination. Nat Med. 2021 01; 27(1):152-164. PMID: 33398162; PMCID: PMC8095049.
      Citations: 84     Fields:    Translation:HumansAnimalsCells
    16. Parsels LA, Engelke CG, Parsels J, Flanagan SA, Zhang Q, Tanska D, Wahl DR, Canman CE, Lawrence TS, Morgan MA. Combinatorial Efficacy of Olaparib with Radiation and ATR Inhibitor Requires PARP1 Protein in Homologous Recombination-Proficient Pancreatic Cancer. Mol Cancer Ther. 2021 02; 20(2):263-273. PMID: 33268569; PMCID: PMC7867626.
      Citations: 11     Fields:    Translation:HumansAnimals
    17. Werner CK, Nna UJ, Sun H, Wilder-Romans K, Dresser J, Kothari AU, Zhou W, Yao Y, Rao A, Stallard S, Koschmann C, Bor T, Debinski W, Hegedus AM, Morgan MA, Venneti S, Baskin-Bey E, Spratt DE, Colman H, Sarkaria JN, Chinnaiyan AM, Eisner JR, Speers C, Lawrence TS, Strowd RE, Wahl DR. Expression of the Androgen Receptor Governs Radiation Resistance in a Subset of Glioblastomas Vulnerable to Antiandrogen Therapy. Mol Cancer Ther. 2020 10; 19(10):2163-2174. PMID: 32796101; PMCID: PMC7842184.
      Citations: 5     Fields:    Translation:HumansAnimals
    18. Zhou W, Yao Y, Scott AJ, Wilder-Romans K, Dresser JJ, Werner CK, Sun H, Pratt D, Sajjakulnukit P, Zhao SG, Davis M, Nelson BS, Halbrook CJ, Zhang L, Umemura Y, Walker AK, Kachman M, Sarkaria JN, Xiong J, Morgan MA, Rehemtualla A, Castro MG, Lowenstein P, Chandrasekaran S, Lawrence TS, Lyssiotis CA, Wahl DR, Gatto F. Purine metabolism regulates DNA repair and therapy resistance in glioblastoma. Nat Commun. 2020 07 30; 11(1):3811. PMID: 32732914; PMCID: PMC7393131.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    19. Liu Y, Awadia S, Delaney A, Sitto M, Engelke CG, Patel H, Calcaterra A, Zelenka-Wang S, Lee H, Contessa J, Neamati N, Ljungman M, Lawrence TS, Morgan MA, Rehemtulla A. UAE1 inhibition mediates the unfolded protein response, DNA damage and caspase-dependent cell death in pancreatic cancer. Transl Oncol. 2020 Nov; 13(11):100834. PMID: 32688248; PMCID: PMC7369648.
      Citations: 6     
    20. Zhu Z, Achreja A, Meurs N, Animasahun O, Owen S, Mittal A, Parikh P, Lo TW, Franco-Barraza J, Shi J, Gunchick V, Sherman MH, Cukierman E, Pickering AM, Maitra A, Sahai V, Morgan MA, Nagrath S, Lawrence TS, Nagrath D. Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours. Nat Metab. 2020 08; 2(8):775-792. PMID: 32694827; PMCID: PMC7438275.
      Citations: 31     Fields:    Translation:HumansCells
    21. Zhang Q, Wei D, Tan M, Li H, Morgan MA, Sun Y. Transgenic expression of Sag/Rbx2 E3 causes early stage tumor promotion, late stage cytogenesis and acinar loss in the Kras-PDAC model. Neoplasia. 2020 Apr 24; 22(6):242-252. PMID: 32339950; PMCID: PMC7186265.
      Citations:    Fields:    
    22. Lohse I, Lin E, Raghavan S, Owen S, Harouaka R, Herman K, Mehta G, Lawrence TS, Morgan MA, Cuneo KC, Nagrath S, Rivera-B?ez L. Expansion of Circulating Tumor Cells from Patients with Locally Advanced Pancreatic Cancer Enable Patient Derived Xenografts and Functional Studies for Personalized Medicine. Cancers (Basel). 2020 Apr 20; 12(4). PMID: 32326109; PMCID: PMC7225920.
      Citations: 5     
    23. Luo X, Donnelly CR, Gong W, Heath BR, Hao Y, Donnelly LA, Moghbeli T, Tan YS, Lin X, Bellile E, Kansy BA, Carey TE, Brenner JC, Cheng L, Polverini PJ, Morgan MA, Wen H, Prince ME, Ferris RL, Xie Y, Young S, Wolf GT, Chen Q, Lei YL. HPV16 drives cancer immune escape via NLRX1-mediated degradation of STING. J Clin Invest. 2020 04 01; 130(4):1635-1652. PMID: 31874109; PMCID: PMC7108911.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    24. Lang X, Green MD, Wang W, Yu J, Choi JE, Jiang L, Liao P, Zhou J, Zhang Q, Dow A, Saripalli AL, Kryczek I, Wei S, Szeliga W, Vatan L, Stone EM, Georgiou G, Cieslik M, Wahl DR, Morgan MA, Chinnaiyan AM, Lawrence TS, Zou W. Radiotherapy and Immunotherapy Promote Tumoral Lipid Oxidation and Ferroptosis via Synergistic Repression of SLC7A11. Cancer Discov. 2019 12; 9(12):1673-1685. PMID: 31554642; PMCID: PMC6891128.
      Citations: 198     Fields:    Translation:HumansAnimalsCells
    25. Cuneo KC, Morgan MA, Sahai V, Schipper MJ, Parsels LA, Parsels JD, Devasia T, Al-Hawaray M, Cho CS, Nathan H, Maybaum J, Zalupski MM, Lawrence TS. Dose Escalation Trial of the Wee1 Inhibitor Adavosertib (AZD1775) in Combination With Gemcitabine and Radiation for Patients With Locally Advanced Pancreatic Cancer. J Clin Oncol. 2019 10 10; 37(29):2643-2650. PMID: 31398082; PMCID: PMC7006846.
      Citations: 47     Fields:    Translation:HumansCTClinical Trials
    26. Zhang Q, Green MD, Lang X, Lazarus J, Parsels JD, Wei S, Parsels LA, Shi J, Ramnath N, Wahl DR, Pasca di Magliano M, Frankel TL, Kryczek I, Lei YL, Lawrence TS, Zou W, Morgan MA. Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy. Cancer Res. 2019 Aug 01; 79(15):3940-3951. PMID: 31101760; PMCID: PMC6684166.
      Citations: 63     Fields:    Translation:HumansAnimalsCells
    27. Zhang Q, Mady ASA, Ma Y, Ryan C, Lawrence TS, Nikolovska-Coleska Z, Sun Y, Morgan MA. The WD40 domain of FBXW7 is a poly(ADP-ribose)-binding domain that mediates the early DNA damage response. Nucleic Acids Res. 2019 05 07; 47(8):4039-4053. PMID: 30722038; PMCID: PMC6486556.
      Citations: 9     Fields:    Translation:HumansCells
    28. Chefetz I, Grimley E, Yang K, Hong L, Vinogradova EV, Suciu R, Kovalenko I, Karnak D, Morgan CA, Chtcherbinine M, Buchman C, Huddle B, Barraza S, Morgan M, Bernstein KA, Yoon E, Lombard DB, Bild A, Mehta G, Romero I, Chiang CY, Landen C, Cravatt B, Hurley TD, Larsen SD, Buckanovich RJ. A Pan-ALDH1A Inhibitor Induces Necroptosis in Ovarian Cancer Stem-like Cells. Cell Rep. 2019 03 12; 26(11):3061-3075.e6. PMID: 30865894; PMCID: PMC7061440.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    29. Morgan MA, Canman CE. Replication Stress: An Achilles' Heel of Glioma Cancer Stem-like Cells. Cancer Res. 2018 12 15; 78(24):6713-6716. PMID: 30498082; PMCID: PMC6295240.
      Citations: 13     Fields:    Translation:HumansCells
    30. Parsels LA, Parsels JD, Tanska DM, Maybaum J, Lawrence TS, Morgan MA. The contribution of DNA replication stress marked by high-intensity, pan-nuclear ?H2AX staining to chemosensitization by CHK1 and WEE1 inhibitors. Cell Cycle. 2018; 17(9):1076-1086. PMID: 29895190; PMCID: PMC6110577.
      Citations: 17     Fields:    Translation:HumansCells
    31. Kirsch DG, Diehn M, Kesarwala AH, Maity A, Morgan MA, Schwarz JK, Bristow R, Demaria S, Eke I, Griffin RJ, Haas-Kogan D, Higgins GS, Kimmelman AC, Kimple RJ, Lombaert IM, Ma L, Marples B, Pajonk F, Park CC, Tran PT, Bernhard EJ, Schaue D. The Future of Radiobiology. J Natl Cancer Inst. 2018 04 01; 110(4):329-340. PMID: 29126306; PMCID: PMC5928778.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    32. Parsels LA, Karnak D, Parsels JD, Zhang Q, Reichert ZR, Wahl DR, Maybaum J, O'Connor MJ, Lawrence TS, Morgan MA, V?lez-Padilla J. PARP1 Trapping and DNA Replication Stress Enhance Radiosensitization with Combined WEE1 and PARP Inhibitors. Mol Cancer Res. 2018 02; 16(2):222-232. PMID: 29133592; PMCID: PMC5805596.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    33. Roberson PL, Smith LB, Morgan MA, Schipper MJ, Wilderman SJ, Avram AM, Kaminski MS, Dewaraja YK. Beyond Dose: Using Pretherapy Biomarkers to Improve Dose Prediction of Outcomes for Radioimmunotherapy of Non-Hodgkin Lymphoma. Cancer Biother Radiopharm. 2017 Nov; 32(9):309-319. PMID: 29083933; PMCID: PMC5695749.
      Citations:    Fields:    Translation:Humans
    34. Cuneo KC, Morgan MA, Griffith KA, Hawkins PG, Greenson JK, Ben-Josef E, Lawrence TS, Zalupski MM. Prognostic Value of c-MET Expression in Patients With Pancreatic Cancer Receiving Adjuvant and Neoadjuvant Chemoradiation Therapy. Int J Radiat Oncol Biol Phys. 2018 02 01; 100(2):490-497. PMID: 29229329; PMCID: PMC6444352.
      Citations: 5     Fields:    Translation:Humans
    35. Merandy K, Morgan MA, Lee R, Scherr DS. Improving Self-Efficacy and Self-Care in Adult Patients With a Urinary Diversion: A Pilot Study. Oncol Nurs Forum. 2017 05 01; 44(3):E90-E100. PMID: 28635980; PMCID: PMC5553720.
      Citations: 2     Fields:    Translation:Humans
    36. An M, Lohse I, Tan Z, Zhu J, Wu J, Kurapati H, Morgan MA, Lawrence TS, Cuneo KC, Lubman DM. Quantitative Proteomic Analysis of Serum Exosomes from Patients with Locally Advanced Pancreatic Cancer Undergoing Chemoradiotherapy. J Proteome Res. 2017 04 07; 16(4):1763-1772. PMID: 28240915; PMCID: PMC5462613.
      Citations: 36     Fields:    Translation:HumansCells
    37. Wahl DR, Dresser J, Wilder-Romans K, Parsels JD, Zhao SG, Davis M, Zhao L, Kachman M, Wernisch S, Burant CF, Morgan MA, Feng FY, Speers C, Lyssiotis CA, Lawrence TS. Glioblastoma Therapy Can Be Augmented by Targeting IDH1-Mediated NADPH Biosynthesis. Cancer Res. 2017 02 15; 77(4):960-970. PMID: 27923831; PMCID: PMC5726266.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    38. Zhang Q, Zhang Y, Parsels JD, Lohse I, Lawrence TS, Pasca di Magliano M, Sun Y, Morgan MA. Fbxw7 Deletion Accelerates KrasG12D-Driven Pancreatic Tumorigenesis via Yap Accumulation. Neoplasia. 2016 Nov; 18(11):666-673. PMID: 27764699; PMCID: PMC5071541.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    39. Reichert ZR, Wahl DR, Morgan MA. Translation of Targeted Radiation Sensitizers into Clinical Trials. Semin Radiat Oncol. 2016 10; 26(4):261-70. PMID: 27619248.
      Citations: 7     Fields:    Translation:HumansCells
    40. Cuneo KC, Morgan MA, Davis MA, Parcels LA, Parcels J, Karnak D, Ryan C, Liu N, Maybaum J, Lawrence TS. Wee1 Kinase Inhibitor AZD1775 Radiosensitizes Hepatocellular Carcinoma Regardless of TP53 Mutational Status Through Induction of Replication Stress. Int J Radiat Oncol Biol Phys. 2016 06 01; 95(2):782-90. PMID: 26975930; PMCID: PMC6644066.
      Citations: 24     Fields:    Translation:HumansCells
    41. Zhang Q, Karnak D, Tan M, Lawrence TS, Morgan MA, Sun Y. FBXW7 Facilitates Nonhomologous End-Joining via K63-Linked Polyubiquitylation of XRCC4. Mol Cell. 2016 Feb 04; 61(3):419-433. PMID: 26774286; PMCID: PMC4744117.
      Citations: 52     Fields:    Translation:HumansAnimalsCells
    42. Parsels LA, Tanska DM, Parsels JD, Zabludoff SD, Cuneo KC, Lawrence TS, Maybaum J, Morgan MA. Dissociation of gemcitabine chemosensitization by CHK1 inhibition from cell cycle checkpoint abrogation and aberrant mitotic entry. Cell Cycle. 2016; 15(5):730-9. PMID: 26890478; PMCID: PMC4845922.
      Citations: 9     Fields:    Translation:HumansCells
    43. Kausar T, Schreiber JS, Karnak D, Parsels LA, Parsels JD, Davis MA, Zhao L, Maybaum J, Lawrence TS, Morgan MA. Sensitization of Pancreatic Cancers to Gemcitabine Chemoradiation by WEE1 Kinase Inhibition Depends on Homologous Recombination Repair. Neoplasia. 2015 Oct; 17(10):757-66. PMID: 26585231; PMCID: PMC4656803.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    44. Ben-Josef E, George A, Regine WF, Abrams R, Morgan M, Thomas D, Schaefer PL, DiPetrillo TA, Fromm M, Small W, Narayan S, Winter K, Griffith KA, Guha C, Williams TM. Glycogen Synthase Kinase 3 Beta Predicts Survival in Resected Adenocarcinoma of the Pancreas. Clin Cancer Res. 2015 Dec 15; 21(24):5612-8. PMID: 26240274; PMCID: PMC4681598.
      Citations: 2     Fields:    Translation:Humans
    45. Morgan MA, Lawrence TS. Molecular Pathways: Overcoming Radiation Resistance by Targeting DNA Damage Response Pathways. Clin Cancer Res. 2015 Jul 01; 21(13):2898-904. PMID: 26133775; PMCID: PMC4494107.
      Citations: 90     Fields:    Translation:HumansCells
    46. Chatterjee M, Ben-Josef E, Thomas DG, Morgan MA, Zalupski MM, Khan G, Andrew Robinson C, Griffith KA, Chen CS, Ludwig T, Bekaii-Saab T, Chakravarti A, Williams TM. Caveolin-1 is Associated with Tumor Progression and Confers a Multi-Modality Resistance Phenotype in Pancreatic Cancer. Sci Rep. 2015 Jun 12; 5:10867. PMID: 26065715; PMCID: PMC4464260.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    47. Wei D, Zhang Q, Schreiber JS, Parsels LA, Abulwerdi FA, Kausar T, Lawrence TS, Sun Y, Nikolovska-Coleska Z, Morgan MA. Targeting mcl-1 for radiosensitization of pancreatic cancers. Transl Oncol. 2015 Feb; 8(1):47-54. PMID: 25749177; PMCID: PMC4350640.
      Citations: 16     
    48. Estrada-Bernal A, Chatterjee M, Haque SJ, Yang L, Morgan MA, Kotian S, Morrell D, Chakravarti A, Williams TM. MEK inhibitor GSK1120212-mediated radiosensitization of pancreatic cancer cells involves inhibition of DNA double-strand break repair pathways. Cell Cycle. 2015; 14(23):3713-24. PMID: 26505547; PMCID: PMC4825728.
      Citations: 29     Fields:    Translation:HumansCells
    49. Karnak D, Engelke CG, Parsels LA, Kausar T, Wei D, Robertson JR, Marsh KB, Davis MA, Zhao L, Maybaum J, Lawrence TS, Morgan MA. Combined inhibition of Wee1 and PARP1/2 for radiosensitization in pancreatic cancer. Clin Cancer Res. 2014 Oct 01; 20(19):5085-96. PMID: 25117293; PMCID: PMC4184968.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    50. Zhao Y, Morgan MA, Sun Y. Targeting Neddylation pathways to inactivate cullin-RING ligases for anticancer therapy. Antioxid Redox Signal. 2014 Dec 10; 21(17):2383-400. PMID: 24410571; PMCID: PMC4241876.
      Citations: 83     Fields:    Translation:Humans
    51. Morgan MA, Parsels LA, Maybaum J, Lawrence TS. Improving the efficacy of chemoradiation with targeted agents. Cancer Discov. 2014 Mar; 4(3):280-91. PMID: 24550033; PMCID: PMC3947675.
      Citations: 41     Fields:    Translation:HumansCells
    52. Grabauskiene S, Bergeron EJ, Chen G, Thomas DG, Giordano TJ, Beer DG, Morgan MA, Reddy RM. Checkpoint kinase 1 protein expression indicates sensitization to therapy by checkpoint kinase 1 inhibition in non-small cell lung cancer. J Surg Res. 2014 Mar; 187(1):6-13. PMID: 24418519; PMCID: PMC4073630.
      Citations: 12     Fields:    Translation:HumansCells
    53. Grabauskiene S, Bergeron EJ, Chen G, Chang AC, Lin J, Thomas DG, Giordano TJ, Beer DG, Morgan MA, Reddy RM. CHK1 levels correlate with sensitization to pemetrexed by CHK1 inhibitors in non-small cell lung cancer cells. Lung Cancer. 2013 Dec; 82(3):477-84. PMID: 24113549; PMCID: PMC4073640.
      Citations: 21     Fields:    Translation:Humans
    54. Zhang Q, Bhojani MS, Ben-Josef E, Spalding AC, Kuick R, Sun Y, Morgan MA. Glycogen Synthase Kinase 3? in Pancreatic Cancer and its Implications in Chemotherapy and Radiation Therapy. J Carcinog Mutagen. 2013 Aug 16; 4(3):147. PMID: 24944842; PMCID: PMC4059685.
      Citations: 4     
    55. Engelke CG, Parsels LA, Qian Y, Zhang Q, Karnak D, Robertson JR, Tanska DM, Wei D, Davis MA, Parsels JD, Zhao L, Greenson JK, Lawrence TS, Maybaum J, Morgan MA. Sensitization of pancreatic cancer to chemoradiation by the Chk1 inhibitor MK8776. Clin Cancer Res. 2013 Aug 15; 19(16):4412-21. PMID: 23804422; PMCID: PMC3745540.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    56. Wei D, Parsels LA, Karnak D, Davis MA, Parsels JD, Marsh AC, Zhao L, Maybaum J, Lawrence TS, Sun Y, Morgan MA. Inhibition of protein phosphatase 2A radiosensitizes pancreatic cancers by modulating CDC25C/CDK1 and homologous recombination repair. Clin Cancer Res. 2013 Aug 15; 19(16):4422-32. PMID: 23780887; PMCID: PMC3754450.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    57. Wei D, Morgan MA, Sun Y. Radiosensitization of Cancer Cells by Inactivation of Cullin-RING E3 Ubiquitin Ligases. Transl Oncol. 2012 Oct; 5(5):305-12. PMID: 23066438; PMCID: PMC3468921.
      Citations: 10     
    58. Venkatesha VA, Parsels LA, Parsels JD, Zhao L, Zabludoff SD, Simeone DM, Maybaum J, Lawrence TS, Morgan MA. Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition. Neoplasia. 2012 Jun; 14(6):519-25. PMID: 22787433; PMCID: PMC3394194.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    59. Vance S, Liu E, Zhao L, Parsels JD, Parsels LA, Brown JL, Maybaum J, Lawrence TS, Morgan MA. Selective radiosensitization of p53 mutant pancreatic cancer cells by combined inhibition of Chk1 and PARP1. Cell Cycle. 2011 Dec 15; 10(24):4321-9. PMID: 22134241; PMCID: PMC3272262.
      Citations: 46     Fields:    Translation:HumansCells
    60. Wei D, Li H, Yu J, Sebolt JT, Zhao L, Lawrence TS, Smith PG, Morgan MA, Sun Y. Radiosensitization of human pancreatic cancer cells by MLN4924, an investigational NEDD8-activating enzyme inhibitor. Cancer Res. 2012 Jan 01; 72(1):282-93. PMID: 22072567; PMCID: PMC3251739.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    61. Yao H, Zeng ZZ, Fay KS, Veine DM, Staszewski ED, Morgan M, Wilder-Romans K, Williams TM, Spalding AC, Ben-Josef E, Livant DL. Role of a(5)?(1) Integrin Up-regulation in Radiation-Induced Invasion by Human Pancreatic Cancer Cells. Transl Oncol. 2011 Oct; 4(5):282-92. PMID: 21966545; PMCID: PMC3162303.
      Citations: 22     
    62. Parsels LA, Qian Y, Tanska DM, Gross M, Zhao L, Hassan MC, Arumugarajah S, Parsels JD, Hylander-Gans L, Simeone DM, Morosini D, Brown JL, Zabludoff SD, Maybaum J, Lawrence TS, Morgan MA. Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition. Clin Cancer Res. 2011 Jun 01; 17(11):3706-15. PMID: 21482692; PMCID: PMC3107893.
      Citations: 45     Fields:    Translation:HumansAnimalsCells
    63. Vilar E, Bartnik CM, Stenzel SL, Raskin L, Ahn J, Moreno V, Mukherjee B, Iniesta MD, Morgan MA, Rennert G, Gruber SB. MRE11 deficiency increases sensitivity to poly(ADP-ribose) polymerase inhibition in microsatellite unstable colorectal cancers. Cancer Res. 2011 Apr 01; 71(7):2632-42. PMID: 21300766; PMCID: PMC3407272.
      Citations: 88     Fields:    Translation:HumansCells
    64. Yang J, McEachern D, Li W, Davis MA, Li H, Morgan MA, Bai L, Sebolt JT, Sun H, Lawrence TS, Wang S, Sun Y. Radiosensitization of head and neck squamous cell carcinoma by a SMAC-mimetic compound, SM-164, requires activation of caspases. Mol Cancer Ther. 2011 Apr; 10(4):658-69. PMID: 21282353; PMCID: PMC3073022.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    65. Zhao L, Morgan MA, Parsels LA, Maybaum J, Lawrence TS, Normolle D. Bayesian hierarchical changepoint methods in modeling the tumor growth profiles in xenograft experiments. Clin Cancer Res. 2011 Mar 01; 17(5):1057-64. PMID: 21131555; PMCID: PMC3048927.
      Citations: 19     Fields:    Translation:Animals
    66. Jia L, Bickel JS, Wu J, Morgan MA, Li H, Yang J, Yu X, Chan RC, Sun Y. RBX1 (RING box protein 1) E3 ubiquitin ligase is required for genomic integrity by modulating DNA replication licensing proteins. J Biol Chem. 2011 Feb 04; 286(5):3379-86. PMID: 21115485; PMCID: PMC3030344.
      Citations: 32     Fields:    Translation:HumansAnimalsCells
    67. Morgan MA, Parsels LA, Zhao L, Parsels JD, Davis MA, Hassan MC, Arumugarajah S, Hylander-Gans L, Morosini D, Simeone DM, Canman CE, Normolle DP, Zabludoff SD, Maybaum J, Lawrence TS. Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair. Cancer Res. 2010 Jun 15; 70(12):4972-81. PMID: 20501833; PMCID: PMC2889008.
      Citations: 149     Fields:    Translation:HumansAnimalsCells
    68. Watson RL, Spalding AC, Zielske SP, Morgan M, Kim AC, Bommer GT, Eldar-Finkelman H, Giordano T, Fearon ER, Hammer GD, Lawrence TS, Ben-Josef E. GSK3beta and beta-catenin modulate radiation cytotoxicity in pancreatic cancer. Neoplasia. 2010 May; 12(5):357-65. PMID: 20454507; PMCID: PMC2864473.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    69. Mierzwa ML, Nyati MK, Morgan MA, Lawrence TS. Recent advances in combined modality therapy. Oncologist. 2010; 15(4):372-81. PMID: 20413642; PMCID: PMC3227964.
      Citations: 8     Fields:    Translation:Humans
    70. Parsels LA, Morgan MA, Tanska DM, Parsels JD, Palmer BD, Booth RJ, Denny WA, Canman CE, Kraker AJ, Lawrence TS, Maybaum J. Gemcitabine sensitization by checkpoint kinase 1 inhibition correlates with inhibition of a Rad51 DNA damage response in pancreatic cancer cells. Mol Cancer Ther. 2009 Jan; 8(1):45-54. PMID: 19139112; PMCID: PMC2730564.
      Citations: 71     Fields:    Translation:HumansCells
    71. Morgan MA, Parsels LA, Maybaum J, Lawrence TS. Improving gemcitabine-mediated radiosensitization using molecularly targeted therapy: a review. Clin Cancer Res. 2008 Nov 01; 14(21):6744-50. PMID: 18980967; PMCID: PMC2697824.
      Citations: 24     Fields:    Translation:Humans
    72. Morgan MA, Parsels LA, Kollar LE, Normolle DP, Maybaum J, Lawrence TS. The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer. Clin Cancer Res. 2008 Aug 15; 14(16):5142-9. PMID: 18698032; PMCID: PMC2699587.
      Citations: 73     Fields:    Translation:HumansAnimalsCells
    73. Morgan M, El Shaikh MA, Abu-Isa E, Davis MA, Lawrence TS. Radiosensitization by gemcitabine fixed-dose-rate infusion versus bolus injection in a pancreatic cancer model. Transl Oncol. 2008 Mar; 1(1):44-9. PMID: 18607504; PMCID: PMC2510760.
      Citations: 7     
    74. Morgan MA, Meirovitz A, Davis MA, Kollar LE, Hassan MC, Lawrence TS. Radiotherapy combined with gemcitabine and oxaliplatin in pancreatic cancer cells. Transl Oncol. 2008 Mar; 1(1):36-43. PMID: 18607506; PMCID: PMC2510762.
      Citations: 15     
    75. Nyati MK, Morgan MA, Feng FY, Lawrence TS. Integration of EGFR inhibitors with radiochemotherapy. Nat Rev Cancer. 2006 11; 6(11):876-85. PMID: 17036041.
      Citations: 107     Fields:    Translation:HumansAnimals
    76. Morgan MA, Parsels LA, Parsels JD, Lawrence TS, Maybaum J. The relationship of premature mitosis to cytotoxicity in response to checkpoint abrogation and antimetabolite treatment. Cell Cycle. 2006 Sep; 5(17):1983-8. PMID: 16931916.
      Citations: 32     Fields:    Translation:HumansCells
    77. Morgan MA, Parsels LA, Parsels JD, Mesiwala AK, Maybaum J, Lawrence TS. Role of checkpoint kinase 1 in preventing premature mitosis in response to gemcitabine. Cancer Res. 2005 Aug 01; 65(15):6835-42. PMID: 16061666.
      Citations: 57     Fields:    Translation:HumansCells
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