VIJAY K. YECHOOR

TitleAdjunct Associate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address
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    K08DK068391     (YECHOOR, VIJAY K)Jul 1, 2004 - Jun 30, 2009
    NIH/NIDDK
    Islet Neogenesis with Ngn3 Therapy Reverses Diabetes
    Role: Principal Investigator

    R03DK078716     (YECHOOR, VIJAY K)Jan 1, 2009 - Dec 31, 2010
    NIH/NIDDK
    Reversing Autoimmune Diabetes with Gene Therapy Induced Islet Neogenesis
    Role: Principal Investigator

    R56DK089061     (YECHOOR, VIJAY K)Jul 1, 2010 - Jun 30, 2012
    NIH/NIDDK
    Circadian Control of Islet Function
    Role: Principal Investigator

    R01DK097160     (YECHOOR, VIJAY K)Feb 1, 2014 - May 31, 2019
    NIH/NIDDK
    Circadian Clock and Beta Cell Stress Adaptation
    Role: Principal Investigator

    I01BX002678     (YECHOOR, VIJAY K)Jan 1, 2016 - Dec 31, 2019
    VA
    Tead1 - A Regulator of Quiescence and Proliferation in Pancreatic Beta Cells
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Xiong X, Gao H, Lin Y, Yechoor V, Ma K. Inhibition of Rev-erba ameliorates muscular dystrophy. Exp Cell Res. 2021 09 15; 406(2):112766. PMID: 34364881.
      Citations:    Fields:    Translation:AnimalsCells
    2. Saydmohammed M, Jha A, Mahajan V, Gavlock D, Shun TY, DeBiasio R, Lefever D, Li X, Reese C, Kershaw EE, Yechoor V, Behari J, Soto-Gutierrez A, Vernetti L, Stern A, Gough A, Miedel MT, Lansing Taylor D. Quantifying the progression of non-alcoholic fatty liver disease in human biomimetic liver microphysiology systems with fluorescent protein biosensors. Exp Biol Med (Maywood). 2021 Nov; 246(22):2420-2441. PMID: 33957803.
      Citations:    Fields:    
    3. Aslanoglou D, Bertera S, Sánchez-Soto M, Benjamin Free R, Lee J, Zong W, Xue X, Shrestha S, Brissova M, Logan RW, Wollheim CB, Trucco M, Yechoor VK, Sibley DR, Bottino R, Freyberg Z. Dopamine regulates pancreatic glucagon and insulin secretion via adrenergic and dopaminergic receptors. Transl Psychiatry. 2021 02 16; 11(1):59. PMID: 33589583.
      Citations: 3     Fields:    
    4. Figueiro MG, Goo YH, Hogan R, Plitnick B, Lee JK, Jahangir K, Moulik M, Yechoor VK, Paul A. Light-Dark Patterns Mirroring Shift Work Accelerate Atherosclerosis and Promote Vulnerable Lesion Phenotypes. J Am Heart Assoc. 2021 01 19; 10(2):e018151. PMID: 33401929.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    5. Xiong X, Lin Y, Lee J, Paul A, Yechoor V, Figueiro M, Ma K. Chronic circadian shift leads to adipose tissue inflammation and fibrosis. Mol Cell Endocrinol. 2021 02 05; 521:111110. PMID: 33285245.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Liu R, Xiong X, Nam D, Yechoor V, Ma K. SRF-MRTF signaling suppresses brown adipocyte development by modulating TGF-ß/BMP pathway. Mol Cell Endocrinol. 2020 09 15; 515:110920. PMID: 32603734.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    7. Liu R, Jagannathan R, Sun L, Li F, Yang P, Lee J, Negi V, Perez-Garcia EM, Shiva S, Yechoor VK, Moulik M. Tead1 is essential for mitochondrial function in cardiomyocytes. Am J Physiol Heart Circ Physiol. 2020 07 01; 319(1):H89-H99. PMID: 32502376.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Yin H, Li W, Chatterjee S, Xiong X, Saha P, Yechoor V, Ma K. Metabolic-sensing of the skeletal muscle clock coordinates fuel oxidation. FASEB J. 2020 05; 34(5):6613-6627. PMID: 32212194.
      Citations: 2     Fields:    Translation:Animals
    9. Liu H, Zhang CH, Ammanamanchi N, Suresh S, Lewarchik C, Rao K, Uys GM, Han L, Abrial M, Yimlamai D, Ganapathy B, Guillermier C, Chen N, Khaladkar M, Spaethling J, Eberwine JH, Kim J, Walsh S, Choudhury S, Little K, Francis K, Sharma M, Viegas M, Bais A, Kostka D, Ding J, Bar-Joseph Z, Wu Y, Yechoor V, Moulik M, Johnson J, Weinberg J, Reyes-Múgica M, Steinhauser ML, Kühn B. Control of cytokinesis by ß-adrenergic receptors indicates an approach for regulating cardiomyocyte endowment. Sci Transl Med. 2019 10 09; 11(513). PMID: 31597755.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    10. Chatterjee S, Yin H, Li W, Lee J, Yechoor VK, Ma K. The Nuclear Receptor and Clock Repressor Rev-erba Suppresses Myogenesis. Sci Rep. 2019 03 14; 9(1):4585. PMID: 30872796.
      Citations: 5     Fields:    Translation:AnimalsCells
    11. Liu R, Jagannathan R, Li F, Lee J, Balasubramanyam N, Kim BS, Yang P, Yechoor VK, Moulik M. Tead1 is required for perinatal cardiomyocyte proliferation. PLoS One. 2019; 14(2):e0212017. PMID: 30811446.
      Citations: 6     Fields:    Translation:AnimalsCells
    12. Xie A, Li R, Jiang T, Yan H, Zhang H, Yang Y, Yang L, Yechoor V, Chan L, Chen W. Anti-TCRß mAb in Combination With Neurogenin3 Gene Therapy Reverses Established Overt Type 1 Diabetes in Female NOD Mice. Endocrinology. 2017 10 01; 158(10):3140-3151. PMID: 28977608.
      Citations: 2     Fields:    Translation:AnimalsCells
    13. Gao H, Ho E, Balakrishnan M, Yechoor V, Yallampalli C. Decreased insulin secretion in pregnant rats fed a low protein diet. Biol Reprod. 2017 Oct 01; 97(4):627-635. PMID: 29025046.
      Citations:    Fields:    Translation:Animals
    14. Liu R, Lee J, Kim BS, Wang Q, Buxton SK, Balasubramanyam N, Kim JJ, Dong J, Zhang A, Li S, Gupte AA, Hamilton DJ, Martin JF, Rodney GG, Coarfa C, Wehrens XH, Yechoor VK, Moulik M. Tead1 is required for maintaining adult cardiomyocyte function, and its loss results in lethal dilated cardiomyopathy. JCI Insight. 2017 09 07; 2(17). PMID: 28878117.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    15. Pradhan G, Wu CS, Han Lee J, Kanikarla P, Guo S, Yechoor VK, Samson SL, Sun Y. Obestatin stimulates glucose-induced insulin secretion through ghrelin receptor GHS-R. Sci Rep. 2017 04 20; 7(1):979. PMID: 28428639.
      Citations: 10     Fields:    Translation:AnimalsCells
    16. Goo YH, Yechoor VK, Paul A. Transcriptional profiling of foam cells in response to hypercholesterolemia. Genom Data. 2016 Sep; 9:37-9. PMID: 27408807.
      Citations: 2     
    17. Goo YH, Son SH, Yechoor VK, Paul A. Transcriptional Profiling of Foam Cells Reveals Induction of Guanylate-Binding Proteins Following Western Diet Acceleration of Atherosclerosis in the Absence of Global Changes in Inflammation. J Am Heart Assoc. 2016 Apr 18; 5(4):e002663. PMID: 27091181.
      Citations: 10     Fields:    Translation:AnimalsCells
    18. Nam D, Yechoor VK, Ma K. Molecular clock integration of brown adipose tissue formation and function. Adipocyte. 2016 Apr-Jun; 5(2):243-50. PMID: 27385482.
      Citations: 6     Fields:    
    19. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. Erratum. PD-L1-Driven Tolerance Protects Neurogenin3-Induced Islet Neogenesis to Reverse Established Type 1 Diabetes in NOD Mice. Diabetes 2015;64:529-540. Diabetes. 2015 Jul; 64(7):2685. PMID: 26106199.
      Citations:    Fields:    
    20. Nam D, Chatterjee S, Yin H, Liu R, Lee J, Yechoor VK, Ma K. Novel Function of Rev-erba in Promoting Brown Adipogenesis. Sci Rep. 2015 Jun 10; 5:11239. PMID: 26058812.
      Citations: 14     Fields:    Translation:Animals
    21. Nam D, Guo B, Chatterjee S, Chen MH, Nelson D, Yechoor VK, Ma K. The adipocyte clock controls brown adipogenesis through the TGF-ß and BMP signaling pathways. J Cell Sci. 2015 May 01; 128(9):1835-47. PMID: 25749863.
      Citations: 26     Fields:    Translation:AnimalsCells
    22. Li R, Lee J, Kim MS, Liu V, Moulik M, Li H, Yi Q, Xie A, Chen W, Yang L, Li Y, Tsai TH, Oka K, Chan L, Yechoor V. PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice. Diabetes. 2015 Feb; 64(2):529-40. PMID: 25332429.
      Citations: 9     Fields:    Translation:AnimalsCells
    23. Lee J, Moulik M, Fang Z, Saha P, Zou F, Xu Y, Nelson DL, Ma K, Moore DD, Yechoor VK. Bmal1 and ß-cell clock are required for adaptation to circadian disruption, and their loss of function leads to oxidative stress-induced ß-cell failure in mice. Mol Cell Biol. 2013 Jun; 33(11):2327-38. PMID: 23547261.
      Citations: 82     Fields:    Translation:AnimalsCells
    24. Chatterjee S, Nam D, Guo B, Kim JM, Winnier GE, Lee J, Berdeaux R, Yechoor VK, Ma K. Brain and muscle Arnt-like 1 is a key regulator of myogenesis. J Cell Sci. 2013 May 15; 126(Pt 10):2213-24. PMID: 23525013.
      Citations: 26     Fields:    Translation:AnimalsCells
    25. Dixit SS, Wang T, Manzano EJ, Yoo S, Lee J, Chiang DY, Ryan N, Respress JL, Yechoor VK, Wehrens XH. Effects of CaMKII-mediated phosphorylation of ryanodine receptor type 2 on islet calcium handling, insulin secretion, and glucose tolerance. PLoS One. 2013; 8(3):e58655. PMID: 23516528.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    26. Li R, Oka K, Yechoor V. Neo-islet formation in liver of diabetic mice by helper-dependent adenoviral vector-mediated gene transfer. J Vis Exp. 2012 Oct 10; (68). PMID: 23093064.
      Citations:    Fields:    Translation:AnimalsCells
    27. Guo B, Chatterjee S, Li L, Kim JM, Lee J, Yechoor VK, Minze LJ, Hsueh W, Ma K. The clock gene, brain and muscle Arnt-like 1, regulates adipogenesis via Wnt signaling pathway. FASEB J. 2012 Aug; 26(8):3453-63. PMID: 22611086.
      Citations: 56     Fields:    Translation:AnimalsCells
    28. Chen W, Chang B, Saha P, Hartig SM, Li L, Reddy VT, Yang Y, Yechoor V, Mancini MA, Chan L. Berardinelli-seip congenital lipodystrophy 2/seipin is a cell-autonomous regulator of lipolysis essential for adipocyte differentiation. Mol Cell Biol. 2012 Mar; 32(6):1099-111. PMID: 22269949.
      Citations: 61     Fields:    Translation:AnimalsCells
    29. Lee J, Kim MS, Li R, Liu VY, Fu L, Moore DD, Ma K, Yechoor VK. Loss of Bmal1 leads to uncoupling and impaired glucose-stimulated insulin secretion in ß-cells. Islets. 2011 Nov-Dec; 3(6):381-8. PMID: 22045262.
      Citations: 45     Fields:    Translation:AnimalsCells
    30. Park YJ, Kim SC, Kim J, Anakk S, Lee JM, Tseng HT, Yechoor V, Park J, Choi JS, Jang HC, Lee KU, Novak CM, Moore DD, Lee YK. Dissociation of diabetes and obesity in mice lacking orphan nuclear receptor small heterodimer partner. J Lipid Res. 2011 Dec; 52(12):2234-2244. PMID: 21949050.
      Citations: 24     Fields:    Translation:AnimalsCells
    31. Yechoor V, Chan L. Minireview: beta-cell replacement therapy for diabetes in the 21st century: manipulation of cell fate by directed differentiation. Mol Endocrinol. 2010 Aug; 24(8):1501-11. PMID: 20219891.
      Citations: 13     Fields:    Translation:HumansCells
    32. Yechoor V, Liu V, Paul A, Lee J, Buras E, Ozer K, Samson S, Chan L. Gene therapy with neurogenin 3 and betacellulin reverses major metabolic problems in insulin-deficient diabetic mice. Endocrinology. 2009 Nov; 150(11):4863-73. PMID: 19819964.
      Citations: 19     Fields:    Translation:HumansAnimals
    33. Chen W, Yechoor VK, Chang BH, Li MV, March KL, Chan L. The human lipodystrophy gene product Berardinelli-Seip congenital lipodystrophy 2/seipin plays a key role in adipocyte differentiation. Endocrinology. 2009 Oct; 150(10):4552-61. PMID: 19574402.
      Citations: 59     Fields:    Translation:HumansAnimalsCells
    34. Yechoor V, Liu V, Espiritu C, Paul A, Oka K, Kojima H, Chan L. Neurogenin3 is sufficient for transdetermination of hepatic progenitor cells into neo-islets in vivo but not transdifferentiation of hepatocytes. Dev Cell. 2009 Mar; 16(3):358-73. PMID: 19289082.
      Citations: 84     Fields:    Translation:AnimalsCells
    35. Samson SL, Gonzalez EV, Yechoor V, Bajaj M, Oka K, Chan L. Gene therapy for diabetes: metabolic effects of helper-dependent adenoviral exendin 4 expression in a diet-induced obesity mouse model. Mol Ther. 2008 11; 16(11):1805-12. PMID: 18781141.
      Citations: 17     Fields:    Translation:AnimalsCells
    36. Paul A, Chang BH, Li L, Yechoor VK, Chan L. Deficiency of adipose differentiation-related protein impairs foam cell formation and protects against atherosclerosis. Circ Res. 2008 Jun 20; 102(12):1492-501. PMID: 18483409.
      Citations: 61     Fields:    Translation:AnimalsCells
    37. Paul A, Yechoor V, Raja R, Li L, Chan L. Microarray gene profiling of laser-captured cells: a new tool to study atherosclerosis in mice. Atherosclerosis. 2008 Oct; 200(2):257-63. PMID: 18289551.
      Citations: 4     Fields:    Translation:AnimalsCells
    38. Tseng YH, Butte AJ, Kokkotou E, Yechoor VK, Taniguchi CM, Kriauciunas KM, Cypess AM, Niinobe M, Yoshikawa K, Patti ME, Kahn CR. Prediction of preadipocyte differentiation by gene expression reveals role of insulin receptor substrates and necdin. Nat Cell Biol. 2005 Jun; 7(6):601-11. PMID: 15895078.
      Citations: 85     Fields:    Translation:AnimalsCells
    39. Niendorf ER, Parker JA, Yechoor V, Garber JR, Boiselle PM. Thymic hyperplasia in thyroid cancer patients. J Thorac Imaging. 2005 Feb; 20(1):1-4. PMID: 15729115.
      Citations: 7     Fields:    Translation:Humans
    40. Yechoor VK, Patti ME, Ueki K, Laustsen PG, Saccone R, Rauniyar R, Kahn CR. Distinct pathways of insulin-regulated versus diabetes-regulated gene expression: an in vivo analysis in MIRKO mice. Proc Natl Acad Sci U S A. 2004 Nov 23; 101(47):16525-30. PMID: 15546994.
      Citations: 47     Fields:    Translation:AnimalsCells
    41. Paul A, Ko KW, Li L, Yechoor V, McCrory MA, Szalai AJ, Chan L. C-reactive protein accelerates the progression of atherosclerosis in apolipoprotein E-deficient mice. Circulation. 2004 Feb 10; 109(5):647-55. PMID: 14744975.
      Citations: 90     Fields:    Translation:HumansAnimals
    42. Castro-Chavez F, Yechoor VK, Saha PK, Martinez-Botas J, Wooten EC, Sharma S, O'Connell P, Taegtmeyer H, Chan L. Coordinated upregulation of oxidative pathways and downregulation of lipid biosynthesis underlie obesity resistance in perilipin knockout mice: a microarray gene expression profile. Diabetes. 2003 Nov; 52(11):2666-74. PMID: 14578284.
      Citations: 25     Fields:    Translation:AnimalsCells
    43. Yechoor VK, Patti ME, Saccone R, Kahn CR. Coordinated patterns of gene expression for substrate and energy metabolism in skeletal muscle of diabetic mice. Proc Natl Acad Sci U S A. 2002 Aug 06; 99(16):10587-92. PMID: 12149437.
      Citations: 34     Fields:    Translation:AnimalsCells
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