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AMINA ANN QUTUB

TitleAdjunct Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular Physiology & Biophysics
DivisionMolecular Physiology & Biophysics
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    F32HL085016     (QUTUB, AMINA ANN)May 4, 2006 - Jun 28, 2009
    NIH/NHLBI
    Modeling Intracellular Mechanisms of Hypoxic Response
    Role: Principal Investigator

    R01GM106027     (DIEHL, MICHAEL R)Jun 1, 2013 - Feb 28, 2017
    NIH/NIGMS
    Spatially-delineated System-level Analyses and Control of Cytoskeletal Regulation
    Role: Co-Principal Investigator

    Collapse Bibliographic 
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ruvolo PP, Hu CW, Qiu Y, Ruvolo VR, Go RL, Hubner SE, Coombes KR, Andreeff M, Qutub AA, Kornblau SM. LGALS3 is connected to CD74 in a previously unknown protein network that is associated with poor survival in patients with AML. EBioMedicine. 2019 Jun; 44:126-137. PMID: 31105032.
      View in: PubMed
    2. Hu CW, Qiu Y, Ligeralde A, Raybon AY, Yoo SY, Coombes KR, Qutub AA, Kornblau SM. A quantitative analysis of heterogeneities and hallmarks in acute myelogenous leukaemia. Nat Biomed Eng. 2019 Apr 15. PMID: 30988472.
      View in: PubMed
    3. Hoff FW, Hu CW, Qutub AA, Qiu Y, Hornbaker MJ, Bueso-Ramos C, Abbas HA, Post SM, de Bont ESJM, Kornblau SM. Proteomic Profiling of Acute Promyelocytic Leukemia Identifies Two Protein Signatures Associated with Relapse. Proteomics Clin Appl. 2019 Jan 16; e1800133. PMID: 30650251.
      View in: PubMed
    4. Hoff FW, Hu CW, Qutub AA, Qiu Y, Graver E, Hoang G, Chauhan M, de Bont ESJM, Kornblau SM. Mycoplasma contamination of leukemic cell lines alters protein expression determined by reverse phase protein arrays. Cytotechnology. 2018 Dec; 70(6):1529-1535. PMID: 30191439.
      View in: PubMed
    5. Hoff FW, Hu CW, Qutub AA, de Bont ESJM, Horton TM, Kornblau SM. Shining a light on cell signaling in leukemia through proteomics: relevance for the clinic. Expert Rev Proteomics. 2018 07; 15(7):613-622. PMID: 29898608.
      View in: PubMed
    6. Hoff FW, Hu CW, Qiu Y, Ligeralde A, Yoo SY, Scheurer ME, de Bont ESJM, Qutub AA, Kornblau SM, Horton TM. Recurrent Patterns of Protein Expression Signatures in Pediatric Acute Lymphoblastic Leukemia: Recognition and Therapeutic Guidance. Mol Cancer Res. 2018 08; 16(8):1263-1274. PMID: 29669823.
      View in: PubMed
    7. Hoff FW, Hu CW, Qiu Y, Ligeralde A, Yoo SY, Mahmud H, de Bont ESJM, Qutub AA, Horton TM, Kornblau SM. Recognition of Recurrent Protein Expression Patterns in Pediatric Acute Myeloid Leukemia Identified New Therapeutic Targets. Mol Cancer Res. 2018 08; 16(8):1275-1286. PMID: 29669821.
      View in: PubMed
    8. van Dijk AD, Hu CW, de Bont ESJM, Qiu Y, Hoff FW, Yoo SY, Coombes KR, Qutub AA, Kornblau SM. Histone Modification Patterns Using RPPA-Based Profiling Predict Outcome in Acute Myeloid Leukemia Patients. Proteomics. 2018 04; 18(8):e1700379. PMID: 29505696.
      View in: PubMed
    9. Ozdemir-Kaynak E, Qutub AA, Yesil-Celiktas O. Advances in Glioblastoma Multiforme Treatment: New Models for Nanoparticle Therapy. Front Physiol. 2018; 9:170. PMID: 29615917.
      View in: PubMed
    10. Hu CW, Li H, Qutub AA. Shrinkage Clustering: a fast and size-constrained clustering algorithm for biomedical applications. BMC Bioinformatics. 2018 01 23; 19(1):19. PMID: 29361928.
      View in: PubMed
    11. Long BL, Li H, Mahadevan A, Tang T, Balotin K, Grandel N, Soto J, Wong SY, Abrego A, Li S, Qutub AA. GAIN: A graphical method to automatically analyze individual neurite outgrowth. J Neurosci Methods. 2017 May 01; 283:62-71. PMID: 28336360.
      View in: PubMed
    12. Schultz A, Mehta S, Hu CW, Hoff FW, Horton TM, Kornblau SM, Qutub AA. IDENTIFYING CANCER SPECIFIC METABOLIC SIGNATURES USING CONSTRAINT-BASED MODELS. Pac Symp Biocomput. 2017; 22:485-496. PMID: 27897000.
      View in: PubMed
    13. Quintás-Cardama A, Hu C, Qutub A, Qiu YH, Zhang X, Post SM, Zhang N, Coombes K, Kornblau SM. p53 pathway dysfunction is highly prevalent in acute myeloid leukemia independent of TP53 mutational status. Leukemia. 2017 06; 31(6):1296-1305. PMID: 27885271.
      View in: PubMed
    14. Liu L, Chang Y, Yang T, Noren DP, Long B, Kornblau S, Qutub A, Ye J. Evolution-informed modeling improves outcome prediction for cancers. Evol Appl. 2017 Jan; 10(1):68-76. PMID: 28035236.
      View in: PubMed
    15. Noren DP, Long BL, Norel R, Rrhissorrakrai K, Hess K, Hu CW, Bisberg AJ, Schultz A, Engquist E, Liu L, Lin X, Chen GM, Xie H, Hunter GA, Boutros PC, Stepanov O, Norman T, Friend SH, Stolovitzky G, Kornblau S, Qutub AA. A Crowdsourcing Approach to Developing and Assessing Prediction Algorithms for AML Prognosis. PLoS Comput Biol. 2016 06; 12(6):e1004890. PMID: 27351836.
      View in: PubMed
    16. Schultz A, Qutub AA. Reconstruction of Tissue-Specific Metabolic Networks Using CORDA. PLoS Comput Biol. 2016 Mar; 12(3):e1004808. PMID: 26942765.
      View in: PubMed
    17. Noren DP, Chou WH, Lee SH, Qutub AA, Warmflash A, Wagner DS, Popel AS, Levchenko A. Endothelial cells decode VEGF-mediated Ca2+ signaling patterns to produce distinct functional responses. Sci Signal. 2016 Feb 23; 9(416):ra20. PMID: 26905425.
      View in: PubMed
    18. Hill SM, Heiser LM, Cokelaer T, Unger M, Nesser NK, Carlin DE, Zhang Y, Sokolov A, Paull EO, Wong CK, Graim K, Bivol A, Wang H, Zhu F, Afsari B, Danilova LV, Favorov AV, Lee WS, Taylor D, Hu CW, Long BL, Noren DP, Bisberg AJ, Mills GB, Gray JW, Kellen M, Norman T, Friend S, Qutub AA, Fertig EJ, Guan Y, Song M, Stuart JM, Spellman PT, Koeppl H, Stolovitzky G, Saez-Rodriguez J, Mukherjee S. Inferring causal molecular networks: empirical assessment through a community-based effort. Nat Methods. 2016 Apr; 13(4):310-8. PMID: 26901648.
      View in: PubMed
    19. Hu CW, Kornblau SM, Slater JH, Qutub AA. Progeny Clustering: A Method to Identify Biological Phenotypes. Sci Rep. 2015 Aug 12; 5:12894. PMID: 26267476.
      View in: PubMed
    20. Slater JH, Culver JC, Long BL, Hu CW, Hu J, Birk TF, Qutub AA, Dickinson ME, West JL. Recapitulation and Modulation of the Cellular Architecture of a User-Chosen Cell of Interest Using Cell-Derived, Biomimetic Patterning. ACS Nano. 2015 Jun 23; 9(6):6128-38. PMID: 25988713.
      View in: PubMed
    21. Lin KW, Liao A, Qutub AA. Simulation predicts IGFBP2-HIF1a interaction drives glioblastoma growth. PLoS Comput Biol. 2015 Apr; 11(4):e1004169. PMID: 25884993.
      View in: PubMed
    22. Schultz A, Qutub AA. Predicting internal cell fluxes at sub-optimal growth. BMC Syst Biol. 2015 Apr 03; 9:18. PMID: 25890056.
      View in: PubMed
    23. Kornblau SM, Qutub A, Yao H, York H, Qiu YH, Graber D, Ravandi F, Cortes J, Andreeff M, Zhang N, Coombes KR. Proteomic profiling identifies distinct protein patterns in acute myelogenous leukemia CD34+CD38- stem-like cells. PLoS One. 2013; 8(10):e78453. PMID: 24223100.
      View in: PubMed
    24. Rekhi R, Qutub AA. Systems approaches for synthetic biology: a pathway toward mammalian design. Front Physiol. 2013; 4:285. PMID: 24130532.
      View in: PubMed
    25. Long BL, Rekhi R, Abrego A, Jung J, Qutub AA. Cells as state machines: cell behavior patterns arise during capillary formation as a function of BDNF and VEGF. J Theor Biol. 2013 Jun 07; 326:43-57. PMID: 23266714.
      View in: PubMed
    26. Schweller RM, Zimak J, Duose DY, Qutub AA, Hittelman WN, Diehl MR. Multiplexed in situ immunofluorescence using dynamic DNA complexes. Angew Chem Int Ed Engl. 2012 Sep 10; 51(37):9292-6. PMID: 22893271.
      View in: PubMed
    27. York H, Kornblau SM, Qutub AA. Network analysis of reverse phase protein expression data: characterizing protein signatures in acute myeloid leukemia cytogenetic categories t(8;21) and inv(16). Proteomics. 2012 Jul; 12(13):2084-93. PMID: 22623292.
      View in: PubMed
    28. Kornblau SM, Qiu YH, Zhang N, Singh N, Faderl S, Ferrajoli A, York H, Qutub AA, Coombes KR, Watson DK. Abnormal expression of FLI1 protein is an adverse prognostic factor in acute myeloid leukemia. Blood. 2011 Nov 17; 118(20):5604-12. PMID: 21917756.
      View in: PubMed
    29. Liu G, Qutub AA, Vempati P, Mac Gabhann F, Popel AS. Module-based multiscale simulation of angiogenesis in skeletal muscle. Theor Biol Med Model. 2011 Apr 04; 8:6. PMID: 21463529.
      View in: PubMed
    30. Stefanini MO, Qutub AA, Mac Gabhann F, Popel AS. Computational models of VEGF-associated angiogenic processes in cancer. Math Med Biol. 2012 Mar; 29(1):85-94. PMID: 21266494.
      View in: PubMed
    31. Mac Gabhann F, Qutub AA, Annex BH, Popel AS. Systems biology of pro-angiogenic therapies targeting the VEGF system. Wiley Interdiscip Rev Syst Biol Med. 2010 Nov-Dec; 2(6):694-707. PMID: 20890966.
      View in: PubMed
    32. Qutub AA, Mac Gabhann F, Karagiannis ED, Vempati P, Popel AS. Multiscale models of angiogenesis. IEEE Eng Med Biol Mag. 2009 Mar-Apr; 28(2):14-31. PMID: 19349248.
      View in: PubMed
    33. Qutub AA, Popel AS. Elongation, proliferation & migration differentiate endothelial cell phenotypes and determine capillary sprouting. BMC Syst Biol. 2009 Jan 26; 3:13. PMID: 19171061.
      View in: PubMed
    34. Qutub AA, Liu G, Vempati P, Popel AS. Integration of angiogenesis modules at multiple scales: from molecular to tissue. Pac Symp Biocomput. 2009; 316-27. PMID: 19209711.
      View in: PubMed
    35. Qutub AA, Popel AS. Reactive oxygen species regulate hypoxia-inducible factor 1alpha differentially in cancer and ischemia. Mol Cell Biol. 2008 Aug; 28(16):5106-19. PMID: 18559422.
      View in: PubMed
    36. Qutub AA, Popel AS. Three autocrine feedback loops determine HIF1 alpha expression in chronic hypoxia. Biochim Biophys Acta. 2007 Oct; 1773(10):1511-25. PMID: 17720260.
      View in: PubMed
    37. Qutub AA, Popel AS. A computational model of intracellular oxygen sensing by hypoxia-inducible factor HIF1 alpha. J Cell Sci. 2006 Aug 15; 119(Pt 16):3467-80. PMID: 16899821.
      View in: PubMed
    38. Qutub AA, Hunt CA. Glucose transport to the brain: a systems model. Brain Res Brain Res Rev. 2005 Nov; 49(3):595-617. PMID: 16269321.
      View in: PubMed
    39. Wong DY, Qutub A, Hunt CA. Modeling transport kinetics with StarLogo. Conf Proc IEEE Eng Med Biol Soc. 2004; 2:845-8. PMID: 17271809.
      View in: PubMed
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