TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    2012• Estela E. Medrano Award of Excellence in Aging Research, Baylor College of Medicine

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Shemesh CS, Agarwal P, Lu T, Lee C, Dere RC, Li X, Li C, Jin JY, Girish S, Miles D, Lu D. Pharmacokinetics of polatuzumab vedotin in combination with R/G-CHP in patients with B-cell non-Hodgkin lymphoma. Cancer Chemother Pharmacol. 2020 05; 85(5):831-842. PMID: 32222808.
      Citations:    Fields:    
    2. Xu X, Huang W, Heczey A, Liu D, Guo L, Wood M, Jin J, Courtney AN, Liu B, Di Pierro EJ, Hicks J, Barragan GA, Ngai H, Chen Y, Savoldo B, Dotti G, Metelitsa LS. NKT Cells Coexpressing a GD2-Specific Chimeric Antigen Receptor and IL15 Show Enhanced In Vivo Persistence and Antitumor Activity against Neuroblastoma. Clin Cancer Res. 2019 12 01; 25(23):7126-7138. PMID: 31484667.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    3. Li H, Yu Y, Zhao Y, Wu D, Yu X, Lu J, Chen Z, Zhang H, Hu Y, Zhai Y, Su J, Aheman A, De Las Casas A, Jin J, Xu X, Shi Z, Woodfield SE, Vasudevan SA, Agarwal S, Yan Y, Yang J, Foster JH. Small molecule inhibitor agerafenib effectively suppresses neuroblastoma tumor growth in mouse models via inhibiting ERK MAPK signaling. Cancer Lett. 2019 08 10; 457:129-141. PMID: 31100410.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    4. Jin J, Jin J, Woodfield SE, Patel RH, Jin NG, Shi Y, Liu B, Sun W, Chen X, Yu Y, Vasudevan SA. Targeting LRH-1 in hepatoblastoma cell lines causes decreased proliferation. Oncol Rep. 2019 Jan; 41(1):143-153. PMID: 30320362.
      Citations: 2     Fields:    Translation:HumansCells
    5. Ngai H, Tian G, Courtney AN, Ravari SB, Guo L, Liu B, Jin J, Shen ET, Di Pierro EJ, Metelitsa LS. IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018 10 01; 201(7):2141-2153. PMID: 30111631.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    6. Zhang T, Guan G, Chen T, Jin J, Zhang L, Yao M, Qi X, Zou J, Chen J, Lu F, Chen X. Methylation of PCDH19 predicts poor prognosis of hepatocellular carcinoma. Asia Pac J Clin Oncol. 2018 Oct; 14(5):e352-e358. PMID: 29749051.
      Citations: 5     Fields:    Translation:HumansCells
    7. Woodfield SE, Shi Y, Patel RH, Jin J, Major A, Sarabia SF, Starosolski Z, Zorman B, Gupta SS, Chen Z, Ibarra AM, Bissig KD, Ghaghada KB, Sumazin P, López-Terrada D, Vasudevan SA. A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma. Sci Rep. 2017 12 19; 7(1):17751. PMID: 29259231.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    8. Sun W, Rojas Y, Wang H, Yu Y, Wang Y, Chen Z, Rajapakshe K, Xu X, Huang W, Agarwal S, Patel RH, Woodfield S, Zhao Y, Jin J, Zhang H, Major A, Hicks MJ, Shohet JM, Vasudevan SA, Coarfa C, Yang J, Nuchtern JG. EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma. Oncotarget. 2017 Nov 07; 8(55):94780-94792. PMID: 29212266.
      Citations: 2     Fields:    
    9. Lu J, Guan S, Zhao Y, Yu Y, Woodfield SE, Zhang H, Yang KL, Bieerkehazhi S, Qi L, Li X, Gu J, Xu X, Jin J, Muscal JA, Yang T, Xu GT, Yang J. The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model. Cancer Lett. 2017 08 01; 400:61-68. PMID: 28455243.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    10. Jin J, Valanejad L, Nguyen TP, Lewis K, Wright M, Cast A, Stock L, Timchenko L, Timchenko NA. Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease. Cell Rep. 2016 07 19; 16(3):744-56. PMID: 27373160.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    11. Jin J, Hong IH, Lewis K, Iakova P, Breaux M, Jiang Y, Sullivan E, Jawanmardi N, Timchenko L, Timchenko NA. Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration. Hepatology. 2015 Jan; 61(1):315-25. PMID: 25043739.
      Citations: 13     Fields:    Translation:AnimalsCells
    12. Hong IH, Lewis K, Iakova P, Jin J, Sullivan E, Jawanmardi N, Timchenko L, Timchenko N. Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments. J Biol Chem. 2014 Jan 10; 289(2):1106-18. PMID: 24273171.
      Citations: 13     Fields:    Translation:AnimalsCells
    13. Jiang Y, Jin J, Iakova P, Hernandez JC, Jawanmardi N, Sullivan E, Guo GL, Timchenko NA, Darlington GJ. Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice. Mech Ageing Dev. 2013 Sep; 134(9):407-15. PMID: 24007921.
      Citations: 7     Fields:    Translation:AnimalsCells
    14. Jin J, Iakova P, Jiang Y, Lewis K, Sullivan E, Jawanmardi N, Donehower L, Timchenko L, Timchenko NA. Transcriptional and translational regulation of C/EBPß-HDAC1 protein complexes controls different levels of p53, SIRT1, and PGC1a proteins at the early and late stages of liver cancer. J Biol Chem. 2013 May 17; 288(20):14451-62. PMID: 23564453.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    15. Jin J, Iakova P, Breaux M, Sullivan E, Jawanmardi N, Chen D, Jiang Y, Medrano EM, Timchenko NA. Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis. Cell Rep. 2013 Mar 28; 3(3):831-43. PMID: 23499441.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    16. Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M, Moore D, Timchenko NA. Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer. Hepatology. 2013 Mar; 57(3):1098-106. PMID: 23172628.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    17. Jin YR, Jin JL, Li CH, Piao XX, Jin NG. Ursolic acid enhances mouse liver regeneration after partial hepatectomy. Pharm Biol. 2012 Apr; 50(4):523-8. PMID: 22136205.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    18. Jin J, Iakova P, Jiang Y, Medrano EE, Timchenko NA. The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation. Hepatology. 2011 Sep 02; 54(3):989-98. PMID: 21638299.
      Citations: 29     Fields:    Translation:AnimalsCells
    19. Graham RA, Lum BL, Cheeti S, Jin JY, Jorga K, Von Hoff DD, Rudin CM, Reddy JC, Low JA, Lorusso PM. Pharmacokinetics of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors: the role of alpha-1-acid glycoprotein binding. Clin Cancer Res. 2011 Apr 15; 17(8):2512-20. PMID: 21300760.
      Citations: 35     Fields:    Translation:HumansCellsCTClinical Trials
    20. Jin J, Wang GL, Iakova P, Shi X, Haefliger S, Finegold M, Timchenko NA. Epigenetic changes play critical role in age-associated dysfunctions of the liver. Aging Cell. 2010 Oct; 9(5):895-910. PMID: 20698834.
      Citations: 13     Fields:    Translation:AnimalsCells
    21. Wang GL, Shi X, Haefliger S, Jin J, Major A, Iakova P, Finegold M, Timchenko NA. Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice. J Clin Invest. 2010 Jul; 120(7):2549-62. PMID: 20516642.
      Citations: 31     Fields:    Translation:AnimalsCells
    22. Orellana D, Liu X, Wang GL, Jin J, Iakova P, Timchenko NA. Calmodulin controls liver proliferation via interactions with C/EBPbeta-LAP and C/EBPbeta-LIP. J Biol Chem. 2010 Jul 23; 285(30):23444-56. PMID: 20498378.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    23. Ro S, Park C, Jin J, Zheng H, Blair PJ, Redelman D, Ward SM, Yan W, Sanders KM. A model to study the phenotypic changes of interstitial cells of Cajal in gastrointestinal diseases. Gastroenterology. 2010 Mar; 138(3):1068-78.e1-2. PMID: 19917283.
      Citations: 38     Fields:    Translation:AnimalsCells
    24. Jin J, Wang GL, Salisbury E, Timchenko L, Timchenko NA. GSK3beta-cyclin D3-CUGBP1-eIF2 pathway in aging and in myotonic dystrophy. . 2009 Aug; 8(15):2356-9. PMID: 19571675.
    25. Jin J, Wang GL, Timchenko L, Timchenko NA. GSK3beta and aging liver. Aging (Albany NY). 2009 Jun 22; 1(6):582-5. PMID: 20157540.
      Citations: 15     Fields:    Translation:AnimalsCells
    26. Jin J, Wang GL, Shi X, Darlington GJ, Timchenko NA. The age-associated decline of glycogen synthase kinase 3beta plays a critical role in the inhibition of liver regeneration. Mol Cell Biol. 2009 Jul; 29(14):3867-80. PMID: 19398579.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    27. Kim JM, Koo YK, Jin J, Lee YY, Park S, Yun-Choi HS. Augmentation of U46619 induced human platelet aggregation by aspirin. Platelets. 2009 Mar; 20(2):111-9. PMID: 19235053.
      Citations: 1     Fields:    Translation:HumansCells
    28. Ro S, Park C, Song R, Nguyen D, Jin J, Sanders KM, McCarrey JR, Yan W. Cloning and expression profiling of testis-expressed piRNA-like RNAs. RNA. 2007 Oct; 13(10):1693-702. PMID: 17698640.
      Citations: 38     Fields:    Translation:Animals
    29. Zheng H, Stratton CJ, Morozumi K, Jin J, Yanagimachi R, Yan W. Lack of Spem1 causes aberrant cytoplasm removal, sperm deformation, and male infertility. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6852-7. PMID: 17426145.
      Citations: 34     Fields:    Translation:AnimalsCells
    30. Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W. Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse. Biol Reprod. 2007 Jul; 77(1):37-44. PMID: 17344468.
      Citations: 46     Fields:    Translation:AnimalsCells
    31. Ro S, Park C, Jin J, Sanders KM, Yan W. A PCR-based method for detection and quantification of small RNAs. Biochem Biophys Res Commun. 2006 Dec 22; 351(3):756-63. PMID: 17084816.
      Citations: 59     Fields:    Translation:AnimalsCells
    32. Pyo MK, Kim JM, Jin JL, Chang KC, Lee DH, Yun-Choi HS. Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA2 synthesis and aggregation. Thromb Res. 2007; 120(1):81-6. PMID: 17020781.
      Citations: 7     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    33. Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM, Yan W. Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis. Biol Reprod. 2005 Dec; 73(6):1235-42. PMID: 16107607.
      Citations: 37     Fields:    Translation:AnimalsCells
    34. Lee YY, Jang DS, Jin JL, Yun-Choi HS. Anti-platelet aggregating and anti-oxidative activities of 11-O-(4'-O-methylgalloyl)-bergenin, a new compound isolated from Crassula cv. 'Himaturi'. Planta Med. 2005 Aug; 71(8):776-7. PMID: 16142645.
      Citations: 1     Fields:    Translation:HumansAnimals
    35. Jin JL, Lee S, Lee YY, Heo JE, Kim JM, Yun-Choi HS. Two new non-glycosidic iridoids from the leaves of Campsis grandiflora. Planta Med. 2005 Jun; 71(6):578-80. PMID: 15971135.
      Citations: 1     Fields:    Translation:Animals
    36. Jin JL, Lee S, Lee YY, Kim JM, Heo JE, Yun-Choi HS. Platelet anti-aggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus. Planta Med. 2004 Jun; 70(6):564-6. PMID: 15241893.
      Citations: 4     Fields:    Translation:Animals
    37. Pyo MK, Jin JL, Koo YK, Yun-Choi HS. Phenolic and furan type compounds isolated from Gastrodia elata and their anti-platelet effects. Arch Pharm Res. 2004 Apr; 27(4):381-5. PMID: 15180301.
      Citations: 8     Fields:    Translation:Animals
    38. Jin JL, Lee YY, Heo JE, Lee S, Kim JM, Yun-Choi HS. Anti-platelet pentacyclic triterpenoids from leaves of Campsis grandiflora. Arch Pharm Res. 2004 Apr; 27(4):376-80. PMID: 15180300.
      Citations: 4     Fields:    Translation:Animals
    39. Lee YY, Lee S, Jin JL, Yun-Choi HS. Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas. Arch Pharm Res. 2003 Sep; 26(9):723-6. PMID: 14560920.
      Citations: 16     Fields:    Translation:AnimalsCells
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