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JINGLING JIN

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
DivisionPediatrics-Oncology
AddressDepartment of Pediatrics - Oncology
1102 Bates St., C1750
Houston TX 77030
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Ngai H, Tian G, Courtney AN, Ravari SB, Guo L, Liu B, Jin J, Shen ET, Di Pierro EJ, Metelitsa LS. IL-21 Selectively Protects CD62L+ NKT Cells and Enhances Their Effector Functions for Adoptive Immunotherapy. J Immunol. 2018 Oct 01; 201(7):2141-2153. PMID: 30111631.
      View in: PubMed
    2. Zhang T, Guan G, Chen T, Jin J, Zhang L, Yao M, Qi X, Zou J, Chen J, Lu F, Chen X. Methylation of PCDH19 predicts poor prognosis of hepatocellular carcinoma. Asia Pac J Clin Oncol. 2018 May 11. PMID: 29749051.
      View in: PubMed
    3. Woodfield SE, Shi Y, Patel RH, Jin J, Major A, Sarabia SF, Starosolski Z, Zorman B, Gupta SS, Chen Z, Ibarra AM, Bissig KD, Ghaghada KB, Sumazin P, López-Terrada D, Vasudevan SA. A Novel Cell Line Based Orthotopic Xenograft Mouse Model That Recapitulates Human Hepatoblastoma. Sci Rep. 2017 Dec 19; 7(1):17751. PMID: 29259231.
      View in: PubMed
    4. Sun W, Rojas Y, Wang H, Yu Y, Wang Y, Chen Z, Rajapakshe K, Xu X, Huang W, Agarwal S, Patel RH, Woodfield S, Zhao Y, Jin J, Zhang H, Major A, Hicks MJ, Shohet JM, Vasudevan SA, Coarfa C, Yang J, Nuchtern JG. EWS-FLI1 and RNA helicase A interaction inhibitor YK-4-279 inhibits growth of neuroblastoma. Oncotarget. 2017 Nov 07; 8(55):94780-94792. PMID: 29212266.
      View in: PubMed
    5. Lu J, Guan S, Zhao Y, Yu Y, Woodfield SE, Zhang H, Yang KL, Bieerkehazhi S, Qi L, Li X, Gu J, Xu X, Jin J, Muscal JA, Yang T, Xu GT, Yang J. The second-generation ALK inhibitor alectinib effectively induces apoptosis in human neuroblastoma cells and inhibits tumor growth in a TH-MYCN transgenic neuroblastoma mouse model. Cancer Lett. 2017 08 01; 400:61-68. PMID: 28455243.
      View in: PubMed
    6. Lu D, Gibiansky L, Agarwal P, Dere RC, Li C, Chu YW, Hirata J, Joshi A, Jin JY, Girish S. Integrated Two-Analyte Population Pharmacokinetic Model for Antibody-Drug Conjugates in Patients: Implications for Reducing Pharmacokinetic Sampling. CPT Pharmacometrics Syst Pharmacol. 2016 12; 5(12):665-673. PMID: 27863168.
      View in: PubMed
    7. Jin J, Valanejad L, Nguyen TP, Lewis K, Wright M, Cast A, Stock L, Timchenko L, Timchenko NA. Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease. Cell Rep. 2016 07 19; 16(3):744-56. PMID: 27373160.
      View in: PubMed
    8. Han K, Jin JY, Marchand M, Eppler S, Choong N, Hack SP, Tikoo N, Bruno R, Dresser M, Musib L, Budha NR. Population pharmacokinetics and dosing implications for cobimetinib in patients with solid tumors. Cancer Chemother Pharmacol. 2015 Nov; 76(5):917-24. PMID: 26365290.
      View in: PubMed
    9. Jin J, Hong IH, Lewis K, Iakova P, Breaux M, Jiang Y, Sullivan E, Jawanmardi N, Timchenko L, Timchenko NA. Cooperation of C/EBP family proteins and chromatin remodeling proteins is essential for termination of liver regeneration. Hepatology. 2015 Jan; 61(1):315-25. PMID: 25043739; PMCID: PMC4280321.
    10. Hong IH, Lewis K, Iakova P, Jin J, Sullivan E, Jawanmardi N, Timchenko L, Timchenko N. Age-associated change of C/EBP family proteins causes severe liver injury and acceleration of liver proliferation after CCl4 treatments. J Biol Chem. 2014 Jan 10; 289(2):1106-18. PMID: 24273171; PMCID: PMC3887178.
    11. Jiang Y, Jin J, Iakova P, Hernandez JC, Jawanmardi N, Sullivan E, Guo GL, Timchenko NA, Darlington GJ. Farnesoid X receptor directly regulates xenobiotic detoxification genes in the long-lived Little mice. Mech Ageing Dev. 2013 Sep; 134(9):407-15. PMID: 24007921; PMCID: PMC3845407.
    12. Jin J, Iakova P, Jiang Y, Lewis K, Sullivan E, Jawanmardi N, Donehower L, Timchenko L, Timchenko NA. Transcriptional and translational regulation of C/EBPß-HDAC1 protein complexes controls different levels of p53, SIRT1, and PGC1a proteins at the early and late stages of liver cancer. J Biol Chem. 2013 May 17; 288(20):14451-62. PMID: 23564453; PMCID: PMC3656300.
    13. Jin J, Iakova P, Breaux M, Sullivan E, Jawanmardi N, Chen D, Jiang Y, Medrano EM, Timchenko NA. Increased expression of enzymes of triglyceride synthesis is essential for the development of hepatic steatosis. Cell Rep. 2013 Mar 28; 3(3):831-43. PMID: 23499441; PMCID: PMC3615099.
    14. Jiang Y, Iakova P, Jin J, Sullivan E, Sharin V, Hong IH, Anakk S, Mayor A, Darlington G, Finegold M, Moore D, Timchenko NA. Farnesoid X receptor inhibits gankyrin in mouse livers and prevents development of liver cancer. Hepatology. 2013 Mar; 57(3):1098-106. PMID: 23172628; PMCID: PMC3649861.
    15. Jin YR, Jin JL, Li CH, Piao XX, Jin NG. Ursolic acid enhances mouse liver regeneration after partial hepatectomy. Pharm Biol. 2012 Apr; 50(4):523-8. PMID: 22136205.
      View in: PubMed
    16. Jin J, Iakova P, Jiang Y, Medrano EE, Timchenko NA. The reduction of SIRT1 in livers of old mice leads to impaired body homeostasis and to inhibition of liver proliferation. Hepatology. 2011 Sep 02; 54(3):989-98. PMID: 21638299; PMCID: PMC3242815.
    17. Jin J, Wang GL, Iakova P, Shi X, Haefliger S, Finegold M, Timchenko NA. Epigenetic changes play critical role in age-associated dysfunctions of the liver. Aging Cell. 2010 Oct; 9(5):895-910. PMID: 20698834; PMCID: PMC3046424.
    18. Wang GL, Shi X, Haefliger S, Jin J, Major A, Iakova P, Finegold M, Timchenko NA. Elimination of C/EBPalpha through the ubiquitin-proteasome system promotes the development of liver cancer in mice. J Clin Invest. 2010 Jul; 120(7):2549-62. PMID: 20516642; PMCID: PMC2898600.
    19. Orellana D, Liu X, Wang GL, Jin J, Iakova P, Timchenko NA. Calmodulin controls liver proliferation via interactions with C/EBPbeta-LAP and C/EBPbeta-LIP. J Biol Chem. 2010 Jul 23; 285(30):23444-56. PMID: 20498378; PMCID: PMC2906335.
    20. Park JH, Jin JY, Baek WK, Park SH, Sung HY, Kim YK, Lee J, Song DK. Ambivalent role of gallated catechins in glucose tolerance in humans: a novel insight into non-absorbable gallated catechin-derived inhibitors of glucose absorption. J Physiol Pharmacol. 2009 Dec; 60(4):101-9. PMID: 20065503.
      View in: PubMed
    21. Ro S, Park C, Jin J, Zheng H, Blair PJ, Redelman D, Ward SM, Yan W, Sanders KM. A model to study the phenotypic changes of interstitial cells of Cajal in gastrointestinal diseases. Gastroenterology. 2010 Mar; 138(3):1068-78.e1-2. PMID: 19917283; PMCID: PMC4793910.
    22. Jin J, Wang GL, Salisbury E, Timchenko L, Timchenko NA. GSK3beta-cyclin D3-CUGBP1-eIF2 pathway in aging and in myotonic dystrophy. Cell Cycle. 2009 Aug; 8(15):2356-9. PMID: 19571675.
      View in: PubMed
    23. Jin J, Wang GL, Timchenko L, Timchenko NA. GSK3beta and aging liver. Aging (Albany NY). 2009 Jun 22; 1(6):582-5. PMID: 20157540; PMCID: PMC2806031.
    24. Jin J, Wang GL, Shi X, Darlington GJ, Timchenko NA. The age-associated decline of glycogen synthase kinase 3beta plays a critical role in the inhibition of liver regeneration. Mol Cell Biol. 2009 Jul; 29(14):3867-80. PMID: 19398579; PMCID: PMC2704742.
    25. Kim JM, Koo YK, Jin J, Lee YY, Park S, Yun-Choi HS. Augmentation of U46619 induced human platelet aggregation by aspirin. Platelets. 2009 Mar; 20(2):111-9. PMID: 19235053.
      View in: PubMed
    26. Park SJ, Kim M, Kim NH, Oh MK, Cho JK, Jin JY, Kim IS. Auranofin promotes retinoic acid- or dihydroxyvitamin D3-mediated cell differentiation of promyelocytic leukaemia cells by increasing histone acetylation. Br J Pharmacol. 2008 Jul; 154(6):1196-205. PMID: 18500361; PMCID: PMC2483395.
    27. Ro S, Park C, Song R, Nguyen D, Jin J, Sanders KM, McCarrey JR, Yan W. Cloning and expression profiling of testis-expressed piRNA-like RNAs. RNA. 2007 Oct; 13(10):1693-702. PMID: 17698640; PMCID: PMC1986815.
    28. Zheng H, Stratton CJ, Morozumi K, Jin J, Yanagimachi R, Yan W. Lack of Spem1 causes aberrant cytoplasm removal, sperm deformation, and male infertility. Proc Natl Acad Sci U S A. 2007 Apr 17; 104(16):6852-7. PMID: 17426145; PMCID: PMC1871874.
    29. Zhou L, Li CJ, Wang Y, Xia W, Yao B, Jin JY, Gui JF. Identification and characterization of a MBP isoform specific to hypothalamus in orange-spotted grouper (Epinephelus coioides). J Chem Neuroanat. 2007 Sep; 34(1-2):47-59. PMID: 17513086.
      View in: PubMed
    30. Jin J, Jin N, Zheng H, Ro S, Tafolla D, Sanders KM, Yan W. Catsper3 and Catsper4 are essential for sperm hyperactivated motility and male fertility in the mouse. Biol Reprod. 2007 Jul; 77(1):37-44. PMID: 17344468.
      View in: PubMed
    31. Ro S, Park C, Jin J, Sanders KM, Yan W. A PCR-based method for detection and quantification of small RNAs. Biochem Biophys Res Commun. 2006 Dec 22; 351(3):756-63. PMID: 17084816; PMCID: PMC1934510.
    32. Pyo MK, Kim JM, Jin JL, Chang KC, Lee DH, Yun-Choi HS. Effects of higenamine and its 1-naphthyl analogs, YS-49 and YS-51, on platelet TXA2 synthesis and aggregation. Thromb Res. 2007; 120(1):81-6. PMID: 17020781.
      View in: PubMed
    33. Jin JL, O'Doherty AM, Wang S, Zheng H, Sanders KM, Yan W. Catsper3 and catsper4 encode two cation channel-like proteins exclusively expressed in the testis. Biol Reprod. 2005 Dec; 73(6):1235-42. PMID: 16107607.
      View in: PubMed
    34. Lee YY, Jang DS, Jin JL, Yun-Choi HS. Anti-platelet aggregating and anti-oxidative activities of 11-O-(4'-O-methylgalloyl)-bergenin, a new compound isolated from Crassula cv. 'Himaturi'. Planta Med. 2005 Aug; 71(8):776-7. PMID: 16142645.
      View in: PubMed
    35. Jin JL, Lee S, Lee YY, Heo JE, Kim JM, Yun-Choi HS. Two new non-glycosidic iridoids from the leaves of Campsis grandiflora. Planta Med. 2005 Jun; 71(6):578-80. PMID: 15971135.
      View in: PubMed
    36. Kim DW, Chung YJ, Lee S, Kim YJ, Chung NG, Kim JA, Oh IH, Kim TG, Kim YL, Goh HG, Kim SH, Cho B, Kim HJ, Min CK, Lee JW, Jin JY, Han CW, Kim JW, Min WS, Kim HK, Kim CC, Kim HJ. Pretransplant imatinib can improve the outcome of nonmyeloablative stem cell transplantation without increasing the morbidity in Philadelphia chromosome-positive chronic myeloid leukemia. Leukemia. 2004 Nov; 18(11):1907-9. PMID: 15356641.
      View in: PubMed
    37. Jin JL, Lee S, Lee YY, Kim JM, Heo JE, Yun-Choi HS. Platelet anti-aggregating triterpenoids from the leaves of Acanthopanax senticosus and the fruits of A. sessiliflorus. Planta Med. 2004 Jun; 70(6):564-6. PMID: 15241893.
      View in: PubMed
    38. Kim IS, Jin JY, Lee IH, Park SJ. Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro. Br J Pharmacol. 2004 Jun; 142(4):749-55. PMID: 15159275; PMCID: PMC1575039.
    39. Pyo MK, Jin JL, Koo YK, Yun-Choi HS. Phenolic and furan type compounds isolated from Gastrodia elata and their anti-platelet effects. Arch Pharm Res. 2004 Apr; 27(4):381-5. PMID: 15180301.
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    40. Jin JL, Lee YY, Heo JE, Lee S, Kim JM, Yun-Choi HS. Anti-platelet pentacyclic triterpenoids from leaves of Campsis grandiflora. Arch Pharm Res. 2004 Apr; 27(4):376-80. PMID: 15180300.
      View in: PubMed
    41. Lee YY, Lee S, Jin JL, Yun-Choi HS. Platelet anti-aggregatory effects of coumarins from the roots of Angelica genuflexa and A. gigas. Arch Pharm Res. 2003 Sep; 26(9):723-6. PMID: 14560920.
      View in: PubMed
    42. Han JY, Kim KW, Kim JA, Kang JH, Jin JY, Hong YS, Park SY, Song JS, Park JW, Kim HK, Lee KS, Choi BG. A phase II study of a daily x4 schedule of vinorelbine plus cisplatin for advanced non-small cell lung cancer. Jpn J Clin Oncol. 2000 Oct; 30(10):435-9. PMID: 11185889.
      View in: PubMed
    43. Jin JY, Kim DW, Lee JW, Han CW, Min WS, Park CW, Kim CC, Kim DJ, Kim HK, Song HH. Immune suppression therapy in aplastic anemia: influencing factors on response and survival. Korean J Intern Med. 1995 Jan; 10(1):25-31. PMID: 7626553; PMCID: PMC4532026.
    44. Kim DJ, Kim CC, Kim BK, Kim DW, Lee JW, Jin JY, Han CW, Min WS, Park CW, Kim HK, et al. Allogeneic bone marrow transplantation in Korea: 1983-92. Bone Marrow Transplant. 1994 Jun; 13(6):717-9. PMID: 7920301.
      View in: PubMed
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