TitleAdjunct Assistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Psychiatry & Behavioral Sciences
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Nieto SJ, Haile CN, Quave CB, Harding MJ, Nielsen DA, Meisch RA, Kosten TA. Paternal alcohol exposure reduces acquisition of operant alcohol self-administration and affects Bdnf DNA methylation in male and female offspring. Addict Biol. 2021 Aug 06; e13078. PMID: 34363290.
      Citations:    Fields:    
    2. Haile CN, Carper BA, Nolen TL, Kosten TA. The GABAB receptor positive allosteric modulator ASP8062 reduces operant alcohol self-administration in male and female Sprague Dawley rats. Psychopharmacology (Berl). 2021 Sep; 238(9):2587-2600. PMID: 34228136.
      Citations:    Fields:    
    3. Stone AE, Scheuermann SE, Haile CN, Cuny GD, Velasquez ML, Linhuber JP, Duddupudi AL, Vigliaturo JR, Pravetoni M, Kosten TA, Kosten TR, Norton EB. Fentanyl conjugate vaccine by injected or mucosal delivery with dmLT or LTA1 adjuvants implicates IgA in protection from drug challenge. NPJ Vaccines. 2021 May 13; 6(1):69. PMID: 33986280.
    4. Ling QL, Akasaka H, Chen C, Haile CN, Winoske K, Ruan KH. The Protective Effects of Up-Regulating Prostacyclin Biosynthesis on Neuron Survival in Hippocampus. J Neuroimmune Pharmacol. 2020 06; 15(2):292-308. PMID: 31897976.
      Citations:    Fields:    Translation:AnimalsCells
    5. Arora R, Haile CN, Kosten TA, Wu Y, Ramakrishnan M, Hawkins LD, Orson FM, Kosten TR. Preclinical efficacy of an anti-methamphetamine vaccine using E6020 adjuvant. Am J Addict. 2019 02; 28(2):119-126. PMID: 30701618.
      Citations: 5     Fields:    Translation:Animals
    6. Wilkinson ST, Kiselycznyk C, Banasr M, Webler RD, Haile C, Mathew SJ. Serum and plasma brain-derived neurotrophic factor and response in a randomized controlled trial of riluzole for treatment resistant depression. J Affect Disord. 2018 12 01; 241:514-518. PMID: 30153634.
      Citations: 7     Fields:    Translation:Humans
    7. Mathai DS, Holst M, Rodgman C, Haile CN, Keller J, Hussain MZ, Kosten TR, Newton TF, Verrico CD. Guanfacine Attenuates Adverse Effects of Dronabinol (THC) on Working Memory in Adolescent-Onset Heavy Cannabis Users: A Pilot Study. J Neuropsychiatry Clin Neurosci. 2018; 30(1):66-76. PMID: 28641496.
      Citations: 3     Fields:    Translation:Humans
    8. Ohia-Nwoko O, Haile CN, Kosten TA. Sex differences in the acute locomotor response to methamphetamine in BALB/c mice. Behav Brain Res. 2017 06 01; 327:94-97. PMID: 28359885.
      Citations: 6     Fields:    Translation:Animals
    9. Mahoney JJ, Haile CN, De La Garza R, Thakkar H, Newton TF. Electrocardiographic characteristics in individuals with cocaine use disorder. Am J Addict. 2017 Apr; 26(3):221-227. PMID: 28248441.
      Citations:    Fields:    Translation:Humans
    10. Haile CN, Kosten TA. The peroxisome proliferator-activated receptor alpha agonist fenofibrate attenuates alcohol self-administration in rats. Neuropharmacology. 2017 04; 116:364-370. PMID: 28088358.
      Citations: 8     Fields:    Translation:Animals
    11. De La Garza R, Yoon JH, Thompson-Lake DG, Haile CN, Eisenhofer JD, Newton TF, Mahoney JJ. Treadmill exercise improves fitness and reduces craving and use of cocaine in individuals with concurrent cocaine and tobacco-use disorder. Psychiatry Res. 2016 Nov 30; 245:133-140. PMID: 27541349.
      Citations: 9     Fields:    Translation:Humans
    12. Verrico CD, Haile CN, De La Garza R, Grasing K, Kosten TR, Newton TF. Subjective and Cardiovascular Effects of Intravenous Methamphetamine during Perindopril Maintenance: A Randomized, Double-Blind, Placebo-Controlled Human Laboratory Study. Int J Neuropsychopharmacol. 2016 07; 19(7). PMID: 27207905.
      Citations: 4     Fields:    Translation:Humans
    13. Rodgman C, Verrico CD, Holst M, Thompson-Lake D, Haile CN, De La Garza R, Raskind MA, Newton TF. Doxazosin XL reduces symptoms of posttraumatic stress disorder in veterans with PTSD: a pilot clinical trial. J Clin Psychiatry. 2016 May; 77(5):e561-5. PMID: 27249080.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    14. Haile CN, Kosten TA, Shen XY, O'Malley PW, Winoske KJ, Kinsey BM, Wu Y, Huang Z, Lykissa ED, Naidu N, Cox JA, Arora R, Kosten TR, Orson FM. Altered methamphetamine place conditioning in mice vaccinated with a succinyl-methamphetamine-tetanus-toxoid vaccine. Am J Addict. 2015 Dec; 24(8):748-55. PMID: 26584468.
      Citations: 9     Fields:    Translation:AnimalsPHPublic Health
    15. Newton TF, Haile CN, Mahoney JJ, Shah R, Verrico CD, De La Garza R, Kosten TR. Dopamine D3 receptor-preferring agonist enhances the subjective effects of cocaine in humans. Psychiatry Res. 2015 Nov 30; 230(1):44-9. PMID: 26239766.
      Citations: 2     Fields:    Translation:Humans
    16. Verrico CD, Haile CN, Mahoney JJ, Thompson-Lake DG, Newton TF, De La Garza R. Treatment with modafinil and escitalopram, alone and in combination, on cocaine-induced effects: a randomized, double blind, placebo-controlled human laboratory study. Drug Alcohol Depend. 2014 Aug 01; 141:72-8. PMID: 24928479.
      Citations: 15     Fields:    Translation:Humans
    17. Haile CN, Kosten TR. Pharmacotherapy for stimulant-related disorders. Curr Psychiatry Rep. 2013 Nov; 15(11):415. PMID: 24142188.
      Citations: 9     Fields:    Translation:Humans
    18. Verrico CD, Haile CN, Newton TF, Kosten TR, De La Garza R, De La Garza R. Pharmacotherapeutics for substance-use disorders: a focus on dopaminergic medications. Expert Opin Investig Drugs. 2013 Dec; 22(12):1549-68. PMID: 24033127.
      Citations: 16     Fields:    Translation:HumansAnimals
    19. Haile CN, De La Garza R, Mahoney JJ, Newton TF. Effects of methamphetamine on the noradrenergic activity biomarker salivary alpha-amylase. Drug Alcohol Depend. 2013 Dec 01; 133(2):759-62. PMID: 23968815.
      Citations: 2     Fields:    Translation:Humans
    20. Zhang XY, Chen DC, Xiu MH, Tan YL, Yang FD, Zhang LY, Zhang LY, Haile CN, Kosten TR. Clinical symptoms and cognitive impairment associated with male schizophrenia relate to plasma manganese superoxide dismutase activity: a case-control study. J Psychiatr Res. 2013 Aug; 47(8):1049-53. PMID: 23611682.
      Citations: 5     Fields:    Translation:Humans
    21. Zhang R, Miao Q, Wang C, Zhao R, Li W, Haile CN, Hao W, Zhang XY. Genome-wide DNA methylation analysis in alcohol dependence. Addict Biol. 2013 Mar; 18(2):392-403. PMID: 23387924.
      Citations: 38     Fields:    Translation:HumansCells
    22. Zhang XY, Chen DC, Xiu MH, Luo X, Zuo L, Haile CN, Kosten TA, Kosten TR. BDNF Val66Met variant and smoking in a Chinese population. PLoS One. 2012; 7(12):e53295. PMID: 23285275.
      Citations: 4     Fields:    Translation:Humans
    23. Haile CN, Hao Y, O'Malley PW, Newton TF, Kosten TA. The a1 Antagonist Doxazosin Alters the Behavioral Effects of Cocaine in Rats. Brain Sci. 2012 Nov 13; 2(4):619-33. PMID: 24961263.
      Citations: 6     
    24. Haile CN, De La Garza R, Mahoney JJ, Nielsen DA, Kosten TR, Newton TF. The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial. PLoS One. 2012; 7(11):e47702. PMID: 23144826.
      Citations: 14     Fields:    Translation:Humans
    25. Zhang XY, Chen DC, Xiu MH, Yang FD, Haile CN, Kosten TA, Kosten TR. Gender differences in never-medicated first-episode schizophrenia and medicated chronic schizophrenia patients. J Clin Psychiatry. 2012 Jul; 73(7):1025-33. PMID: 22901352.
      Citations: 25     Fields:    Translation:Humans
    26. Zhang XY, Zhang WF, Zhou DF, Chen DC, Xiu MH, Wu HR, Haile CN, Kosten TA, Kosten TR. Brain-derived neurotrophic factor levels and its Val66Met gene polymorphism predict tardive dyskinesia treatment response to Ginkgo biloba. Biol Psychiatry. 2012 Oct 15; 72(8):700-6. PMID: 22695185.
      Citations: 9     Fields:    Translation:Humans
    27. Zhang XY, Chen DC, Xiu MH, Haile CN, Sun H, Lu L, Kosten TA, Kosten TR. Cigarette smoking and cognitive function in Chinese male schizophrenia: a case-control study. PLoS One. 2012; 7(5):e36563. PMID: 22570726.
      Citations: 11     Fields:    Translation:Humans
    28. Yoon JH, Newton TF, Haile CN, Bordnick PS, Fintzy RE, Culbertson C, Mahoney JJ, Hawkins RY, LaBounty KR, Ross EL, Aziziyeh AI, La Garza R. Effects of D-cycloserine on cue-induced craving and cigarette smoking among concurrent cocaine- and nicotine-dependent volunteers. Addict Behav. 2013 Feb; 38(2):1518-1526. PMID: 22560371.
      Citations: 12     Fields:    Translation:HumansPHPublic Health
    29. Liu H, Kang Y, Liang J, Li C, Xiu M, Chen D, Yang F, Wang F, Wu G, Haile CN, Kosten TA, Kosten TR, Zhang XY. Lower serum interleukin-2 levels in schizophrenic patients with tardive dyskinesia. Psychiatry Res. 2012 Jul 30; 198(2):329-31. PMID: 22417931.
      Citations: 6     Fields:    Translation:Humans
    30. Zhang XY, Chen DC, Xiu MH, Haile CN, Luo X, Xu K, Zhang HP, Zuo L, Zhang Z, Zhang X, Kosten TA, Kosten TR. Cognitive and serum BDNF correlates of BDNF Val66Met gene polymorphism in patients with schizophrenia and normal controls. Hum Genet. 2012 Jul; 131(7):1187-95. PMID: 22362486.
      Citations: 28     Fields:    Translation:Humans
    31. Zhang XY, Liang J, Chen DC, Xiu MH, He J, Cheng W, Wu Z, Yang FD, Haile CN, Sun H, Lu L, Kosten TA, Kosten TR. Cigarette smoking in male patients with chronic schizophrenia in a Chinese population: prevalence and relationship to clinical phenotypes. PLoS One. 2012; 7(2):e30937. PMID: 22347412.
      Citations: 20     Fields:    Translation:Humans
    32. Newton TF, De La Garza R, Brown G, Kosten TR, Mahoney JJ, Haile CN. Noradrenergic a1 receptor antagonist treatment attenuates positive subjective effects of cocaine in humans: a randomized trial. PLoS One. 2012; 7(2):e30854. PMID: 22319592.
      Citations: 24     Fields:    Translation:Humans
    33. Haile CN, Mahoney JJ, Newton TF, De La Garza R. Pharmacotherapeutics directed at deficiencies associated with cocaine dependence: focus on dopamine, norepinephrine and glutamate. Pharmacol Ther. 2012 May; 134(2):260-77. PMID: 22327234.
      Citations: 22     Fields:    Translation:HumansAnimals
    34. Xiang X, Huang W, Haile CN, Kosten TA. Hippocampal GluR1 associates with behavior in the elevated plus maze and shows sex differences. Behav Brain Res. 2011 Sep 23; 222(2):326-31. PMID: 21497621.
      Citations: 10     Fields:    Translation:Animals
    35. Haile CN, De La Garza R, Newton TF. Methamphetamine Cured my Cocaine Addiction. J Addict Res Ther. 2010 Oct 14; 1(103). PMID: 23066512.
      Citations: 3     
    36. Zhang XY, Xiu MH, Song C, Chen DC, Wu GY, Haile CN, Kosten TA, Kosten TR. Increased serum S100B in never-medicated and medicated schizophrenic patients. J Psychiatr Res. 2010 Dec; 44(16):1236-40. PMID: 20510426.
      Citations: 13     Fields:    Translation:Humans
    37. Haile CN, Kosten TR. The potential of pharmacogenomics to treat drug addiction. Pharmacogenomics. 2009 Dec; 10(12):1883-6. PMID: 19958085.
      Citations: 4     Fields:    Translation:Humans
    38. Zhang XY, Xiu MH, Chen DC, Zhu FY, Wu GY, Haile CN, Lu L, Kosten TA, Kosten TR. Increased S100B serum levels in schizophrenic patients with tardive dyskinesia: association with dyskinetic movements. J Psychiatr Res. 2010 May; 44(7):429-33. PMID: 19932492.
      Citations: 6     Fields:    Translation:Humans
    39. Chen JX, Su YA, Wang SL, Bian QT, Liu YH, Wang N, Yang FD, Haile C, Kosten TR, Zhang XY. Aripiprazole treatment of risperidone-induced hyperprolactinemia. J Clin Psychiatry. 2009 Jul; 70(7):1058-9. PMID: 19653986.
      Citations: 4     Fields:    Translation:Humans
    40. Zhang XY, Chen DC, Xiu MH, Wang F, Qi LY, Sun HQ, Chen S, He SC, Wu GY, Haile CN, Kosten TA, Lu L, Kosten TR. The novel oxidative stress marker thioredoxin is increased in first-episode schizophrenic patients. Schizophr Res. 2009 Sep; 113(2-3):151-7. PMID: 19540723.
      Citations: 18     Fields:    Translation:Humans
    41. Haile CN, Kosten TR, Kosten TA. Pharmacogenetic treatments for drug addiction: cocaine, amphetamine and methamphetamine. Am J Drug Alcohol Abuse. 2009; 35(3):161-77. PMID: 19462300.
      Citations: 27     Fields:    Translation:Humans
    42. Haile CN, Kosten TA, Kosten TR. Pharmacogenetic treatments for drug addiction: alcohol and opiates. Am J Drug Alcohol Abuse. 2008; 34(4):355-81. PMID: 18584566.
      Citations: 21     Fields:    Translation:Humans
    43. Zhang XY, Zhou DF, Wu GY, Cao LY, Tan YL, Haile CN, Li J, Lu L, Kosten TA, Kosten TR. BDNF levels and genotype are associated with antipsychotic-induced weight gain in patients with chronic schizophrenia. Neuropsychopharmacology. 2008 Aug; 33(9):2200-5. PMID: 17987059.
      Citations: 30     Fields:    Translation:Humans
    44. Zhang XY, Tan YL, Zhou DF, Haile CN, Cao LY, Xu Q, Shen Y, Kosten TA, Kosten TR. Association of clozapine-induced weight gain with a polymorphism in the leptin promoter region in patients with chronic schizophrenia in a Chinese population. J Clin Psychopharmacol. 2007 Jun; 27(3):246-51. PMID: 17502770.
      Citations: 17     Fields:    Translation:HumansCellsCTClinical Trials
    45. Kosten TA, Karanian DA, Yeh J, Haile CN, Kim JJ, Kehoe P, Bahr BA. Memory impairments and hippocampal modifications in adult rats with neonatal isolation stress experience. Neurobiol Learn Mem. 2007 Sep; 88(2):167-76. PMID: 17543553.
      Citations: 17     Fields:    Translation:Animals
    46. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Haile CN, Kosten TA, Kosten TR. Disrupted antioxidant enzyme activity and elevated lipid peroxidation products in schizophrenic patients with tardive dyskinesia. J Clin Psychiatry. 2007 May; 68(5):754-60. PMID: 17503985.
      Citations: 18     Fields:    Translation:HumansCells
    47. Kosten TA, Zhang XY, Haile CN. Strain differences in maintenance of cocaine self-administration and their relationship to novelty activity responses. Behav Neurosci. 2007 Apr; 121(2):380-8. PMID: 17469928.
      Citations: 21     Fields:    Translation:Animals
    48. Zhang XY, Tan YL, Zhou DF, Haile CN, Wu GY, Cao LY, Kosten TA, Kosten TR. Nicotine dependence, symptoms and oxidative stress in male patients with schizophrenia. Neuropsychopharmacology. 2007 Sep; 32(9):2020-4. PMID: 17228336.
      Citations: 11     Fields:    Translation:Humans
    49. Guo S, Chen DF, Zhou DF, Sun HQ, Wu GY, Haile CN, Kosten TA, Kosten TR, Zhang XY. Association of functional catechol O-methyl transferase (COMT) Val108Met polymorphism with smoking severity and age of smoking initiation in Chinese male smokers. Psychopharmacology (Berl). 2007 Mar; 190(4):449-56. PMID: 17206495.
      Citations: 19     Fields:    Translation:Humans
    50. Zhang XY, Tan YL, Zhou DF, Cao LY, Wu GY, Xu Q, Shen Y, Haile CN, Kosten TA, Kosten TR. Serum BDNF levels and weight gain in schizophrenic patients on long-term treatment with antipsychotics. J Psychiatr Res. 2007 Dec; 41(12):997-1004. PMID: 17095017.
      Citations: 26     Fields:    Translation:Humans
    51. Haile CN, Kosten TR, Kosten TA. Genetics of dopamine and its contribution to cocaine addiction. Behav Genet. 2007 Jan; 37(1):119-45. PMID: 17063402.
      Citations: 17     Fields:    Translation:HumansAnimals
    52. Haile CN, Zhang XY, Carroll FI, Kosten TA. Cocaine self-administration and locomotor activity are altered in Lewis and F344 inbred rats by RTI 336, a 3-phenyltropane analog that binds to the dopamine transporter. Brain Res. 2005 Sep 07; 1055(1-2):186-95. PMID: 16095575.
      Citations: 10     Fields:    Translation:AnimalsCells
    53. Hsu R, Taylor JR, Newton SS, Alvaro JD, Haile C, Han G, Hruby VJ, Nestler EJ, Duman RS. Blockade of melanocortin transmission inhibits cocaine reward. Eur J Neurosci. 2005 Apr; 21(8):2233-42. PMID: 15869520.
      Citations: 39     Fields:    Translation:Animals
    54. Haile CN, During MJ, Jatlow PI, Kosten TR, Kosten TA. Disulfiram facilitates the development and expression of locomotor sensitization to cocaine in rats. Biol Psychiatry. 2003 Nov 01; 54(9):915-21. PMID: 14573319.
      Citations: 20     Fields:    Translation:Animals
    55. During MJ, Cao L, Zuzga DS, Francis JS, Fitzsimons HL, Jiao X, Bland RJ, Klugmann M, Banks WA, Drucker DJ, Haile CN. Glucagon-like peptide-1 receptor is involved in learning and neuroprotection. Nat Med. 2003 Sep; 9(9):1173-9. PMID: 12925848.
      Citations: 219     Fields:    Translation:AnimalsCells
    56. Miserendino MJ, Haile CN, Kosten TA. Strain differences in response to escapable and inescapable novel environments and their ability to predict amphetamine-induced locomotor activity. Psychopharmacology (Berl). 2003 May; 167(3):281-90. PMID: 12664191.
      Citations: 7     Fields:    Translation:Animals
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