 Manganese
"Manganese" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A trace element with atomic symbol Mn, atomic number 25, and atomic weight 54.94. It is concentrated in cell mitochondria, mostly in the pituitary gland, liver, pancreas, kidney, and bone, influences the synthesis of mucopolysaccharides, stimulates hepatic synthesis of cholesterol and fatty acids, and is a cofactor in many enzymes, including arginase and alkaline phosphatase in the liver. (From AMA Drug Evaluations Annual 1992, p2035)
| Descriptor ID |
D008345
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| MeSH Number(s) |
D01.268.556.484 D01.268.956.374 D01.552.544.484
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Manganese".
Below are MeSH descriptors whose meaning is more specific than "Manganese".
This graph shows the total number of publications written about "Manganese" by people in this website by year, and whether "Manganese" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
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| 1990 | 0 | 1 | 1 | | 1991 | 0 | 1 | 1 | | 1992 | 0 | 2 | 2 | | 1993 | 1 | 0 | 1 | | 1994 | 1 | 1 | 2 | | 1995 | 0 | 1 | 1 | | 1998 | 2 | 0 | 2 | | 1999 | 0 | 1 | 1 | | 2000 | 2 | 1 | 3 | | 2001 | 1 | 0 | 1 | | 2002 | 2 | 2 | 4 | | 2003 | 2 | 1 | 3 | | 2004 | 2 | 5 | 7 | | 2005 | 2 | 2 | 4 | | 2006 | 6 | 0 | 6 | | 2007 | 1 | 2 | 3 | | 2008 | 2 | 0 | 2 | | 2009 | 1 | 0 | 1 | | 2010 | 0 | 1 | 1 | | 2011 | 3 | 0 | 3 | | 2012 | 1 | 1 | 2 | | 2014 | 1 | 1 | 2 | | 2015 | 1 | 2 | 3 | | 2016 | 0 | 2 | 2 | | 2017 | 1 | 0 | 1 | | 2018 | 0 | 1 | 1 | | 2019 | 0 | 1 | 1 |
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Below are the most recent publications written about "Manganese" by people in Profiles.
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Lee M, Rahbar MH, Samms-Vaughan M, Bressler J, Bach MA, Hessabi M, Grove ML, Shakespeare-Pellington S, Coore Desai C, Reece JA, Loveland KA, Boerwinkle E. A generalized weighted quantile sum approach for analyzing correlated data in the presence of interactions. Biom J. 2019 07; 61(4):934-954.
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Henderson L, Neumann O, Kaffes C, Zhang R, Marangoni V, Ravoori MK, Kundra V, Bankson J, Nordlander P, Halas NJ. Routes to Potentially Safer T1 Magnetic Resonance Imaging Contrast in a Compact Plasmonic Nanoparticle with Enhanced Fluorescence. ACS Nano. 2018 08 28; 12(8):8214-8223.
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Hutchens S, Liu C, Jursa T, Shawlot W, Chaffee BK, Yin W, Gore AC, Aschner M, Smith DR, Mukhopadhyay S. Deficiency in the manganese efflux transporter SLC30A10 induces severe hypothyroidism in mice. J Biol Chem. 2017 06 09; 292(23):9760-9773.
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Loehr JA, Stinnett GR, Hernández-Rivera M, Roten WT, Wilson LJ, Pautler RG, Rodney GG. Eliminating Nox2 reactive oxygen species production protects dystrophic skeletal muscle from pathological calcium influx assessed in vivo by manganese-enhanced magnetic resonance imaging. J Physiol. 2016 11 01; 594(21):6395-6405.
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Soriano S, Calap-Quintana P, Llorens JV, Al-Ramahi I, Gutiérrez L, Martínez-Sebastián MJ, Botas J, Moltó MD. Metal Homeostasis Regulators Suppress FRDA Phenotypes in a Drosophila Model of the Disease. PLoS One. 2016; 11(7):e0159209.
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Shawki A, Anthony SR, Nose Y, Engevik MA, Niespodzany EJ, Barrientos T, Öhrvik H, Worrell RT, Thiele DJ, Mackenzie B. Intestinal DMT1 is critical for iron absorption in the mouse but is not required for the absorption of copper or manganese. Am J Physiol Gastrointest Liver Physiol. 2015 Oct 15; 309(8):G635-47.
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Bisson C, Britton KL, Sedelnikova SE, Rodgers HF, Eadsforth TC, Viner RC, Hawkes TR, Baker PJ, Rice DW. Crystal Structures Reveal that the Reaction Mechanism of Imidazoleglycerol-Phosphate Dehydratase Is Controlled by Switching Mn(II) Coordination. Structure. 2015 Jul 07; 23(7):1236-45.
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Rahbar MH, Samms-Vaughan M, Dickerson AS, Hessabi M, Bressler J, Desai CC, Shakespeare-Pellington S, Reece JA, Morgan R, Loveland KA, Grove ML, Boerwinkle E. Concentration of lead, mercury, cadmium, aluminum, arsenic and manganese in umbilical cord blood of Jamaican newborns. Int J Environ Res Public Health. 2015 Apr 23; 12(5):4481-501.
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Pena Luengas SL, Marin GH, Aviles K, Cruz Acuña R, Roque G, Rodríguez Nieto F, Sanchez F, Tarditi A, Rivera L, Mansilla E. Enhanced singlet oxygen production by photodynamic therapy and a novel method for its intracellular measurement. Cancer Biother Radiopharm. 2014 Dec; 29(10):435-43.
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Zhao B, Yao Y, Yang K, Rong P, Huang P, Sun K, An X, Li Z, Chen X, Li W. Mercaptopropionic acid-capped Mn(2+):ZnSe/ZnO quantum dots with both downconversion and upconversion emissions for bioimaging applications. Nanoscale. 2014 Nov 07; 6(21):12345-9.
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