"Brain Stem Neoplasms" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Benign and malignant intra-axial tumors of the MESENCEPHALON; PONS; or MEDULLA OBLONGATA of the BRAIN STEM. Primary and metastatic neoplasms may occur in this location. Clinical features include ATAXIA, cranial neuropathies (see CRANIAL NERVE DISEASES), NAUSEA, hemiparesis (see HEMIPLEGIA), and quadriparesis. Primary brain stem neoplasms are more frequent in children. Histologic subtypes include GLIOMA; HEMANGIOBLASTOMA; GANGLIOGLIOMA; and EPENDYMOMA.
| Descriptor ID |
D020295
|
| MeSH Number(s) |
C04.588.614.250.195.411.100 C10.228.140.211.500.100 C10.551.240.250.400.200
|
| Concept/Terms |
Brain Stem Neoplasms- Brain Stem Neoplasms
- Brain Stem Neoplasm
- Neoplasm, Brain Stem
- Neoplasms, Brain Stem
- Brainstem Neoplasms
- Brainstem Neoplasm
- Neoplasm, Brainstem
- Brainstem Tumors
- Brainstem Tumor
- Neoplasms, Brainstem
- Brain Stem Tumors
- Brain Stem Tumor
- Tumor, Brain Stem
Pontine Tumors- Pontine Tumors
- Pontine Tumor
- Tumor, Pontine
- Tumors, Pontine
- Pontine Neoplasms
- Neoplasms, Pontine
- Neoplasm, Pontine
- Pontine Neoplasm
Mesencephalic Neoplasms- Mesencephalic Neoplasms
- Mesencephalic Neoplasm
- Neoplasm, Mesencephalic
- Neoplasms, Midbrain
- Midbrain Tumors
- Midbrain Tumor
- Tumor, Midbrain
- Tumors, Midbrain
- Midbrain Neoplasms
- Midbrain Neoplasm
- Neoplasm, Midbrain
- Neoplasms, Mesencephalic
Brain Stem Neoplasms, Primary- Brain Stem Neoplasms, Primary
- Primary Brainstem Neoplasms
- Primary Brain Stem Neoplasms
- Brainstem Neoplasms, Primary
- Brainstem Neoplasm, Primary
- Neoplasm, Primary Brainstem
- Neoplasms, Primary Brainstem
- Primary Brainstem Neoplasm
- Neoplasms, Brainstem, Primary
Medullary Neoplasms- Medullary Neoplasms
- Medullary Neoplasm
- Neoplasm, Medullary
- Neoplasms, Medullary
- Medullary Tumors
- Medullary Tumor
- Tumor, Medullary
- Tumors, Medullary
|
Below are MeSH descriptors whose meaning is more general than "Brain Stem Neoplasms".
Below are MeSH descriptors whose meaning is more specific than "Brain Stem Neoplasms".
This graph shows the total number of publications written about "Brain Stem Neoplasms" by people in this website by year, and whether "Brain Stem Neoplasms" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 1 | 0 | 1 |
| 2005 | 2 | 0 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2010 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2013 | 1 | 0 | 1 |
| 2014 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2017 | 3 | 0 | 3 |
| 2018 | 1 | 0 | 1 |
| 2019 | 1 | 0 | 1 |
| 2020 | 5 | 0 | 5 |
| 2021 | 1 | 0 | 1 |
| 2022 | 4 | 0 | 4 |
| 2023 | 1 | 0 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Brain Stem Neoplasms" by people in Profiles.
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Intravenous and intracranial GD2-CAR T cells for H3K27M+ diffuse midline gliomas. Nature. 2025 01; 637(8046):708-715.
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Immunotherapy approaches for the treatment of diffuse midline gliomas. Oncoimmunology. 2022; 11(1):2124058.
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Phase I/II trial of vorinostat and radiation and maintenance vorinostat in children with diffuse intrinsic pontine glioma: A Children's Oncology Group report. Neuro Oncol. 2022 04 01; 24(4):655-664.
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GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas. Nature. 2022 03; 603(7903):934-941.
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Neogenin is highly expressed in diffuse intrinsic pontine glioma and influences tumor invasion. Brain Res. 2021 07 01; 1762:147348.
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A phase I/II study of veliparib (ABT-888) with radiation and temozolomide in newly diagnosed diffuse pontine glioma: a Pediatric Brain Tumor Consortium study. Neuro Oncol. 2020 06 09; 22(6):875-885.
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A phase 2 study of valproic acid and radiation, followed by maintenance valproic acid and bevacizumab in children with newly diagnosed diffuse intrinsic pontine glioma or high-grade glioma. Pediatr Blood Cancer. 2020 06; 67(6):e28283.
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Advanced ADC Histogram, Perfusion, and Permeability Metrics Show an Association with Survival and Pseudoprogression in Newly Diagnosed Diffuse Intrinsic Pontine Glioma: A Report from the Pediatric Brain Tumor Consortium. AJNR Am J Neuroradiol. 2020 04; 41(4):718-724.
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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG. Cancer Cell. 2019 11 11; 36(5):528-544.e10.
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A pediatric brain tumor consortium phase II trial of capecitabine rapidly disintegrating tablets with concomitant radiation therapy in children with newly diagnosed diffuse intrinsic pontine gliomas. Pediatr Blood Cancer. 2018 Feb; 65(2).