Left-Right Determination Factors
"Left-Right Determination Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Signaling ligands that act in opposition to NODAL PROTEIN. During vertebrate development they regulate the degree of left-right asymmetry by controlling the spatiotemporal influence of NODAL PROTEIN.
| Descriptor ID |
D055458
|
| MeSH Number(s) |
D12.644.276.954.550.475 D12.776.467.942.550.475 D23.529.942.550.475
|
| Concept/Terms |
Left-Right Determination Factors- Left-Right Determination Factors
- Determination Factors, Left-Right
- Left Right Determination Factors
- Lefty Proteins
- Left-Right Determination Factor Proteins
- Left Right Determination Factor Proteins
Left-Right Determination Factor 1- Left-Right Determination Factor 1
- Left Right Determination Factor 1
- Left-Right Determination, Factor B
- Left Right Determination, Factor B
Left-Right Determination Factor 2- Left-Right Determination Factor 2
- Left Right Determination Factor 2
- Left-Right Determination Factor A
- Left Right Determination Factor A
|
Below are MeSH descriptors whose meaning is more general than "Left-Right Determination Factors".
Below are MeSH descriptors whose meaning is more specific than "Left-Right Determination Factors".
This graph shows the total number of publications written about "Left-Right Determination Factors" by people in this website by year, and whether "Left-Right Determination Factors" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2000 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
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Below are the most recent publications written about "Left-Right Determination Factors" by people in Profiles.
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Polaris and Polycystin-2 in dorsal forerunner cells and Kupffer's vesicle are required for specification of the zebrafish left-right axis. Dev Biol. 2005 Nov 15; 287(2):274-88.
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Decidual differentiation of stromal cells promotes Proprotein Convertase 5/6 expression and lefty processing. Endocrinology. 2005 Dec; 146(12):5313-20.
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Molecular genetics of heterotaxy syndromes. Curr Opin Cardiol. 2004 May; 19(3):216-20.
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Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo. Nature. 2004 Mar 25; 428(6981):387-92.
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Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks. Dev Cell. 2002 Nov; 3(5):745-56.
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Smad5 is essential for left-right asymmetry in mice. Dev Biol. 2000 Mar 01; 219(1):71-8.
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Characterization and mutation analysis of human LEFTY A and LEFTY B, homologues of murine genes implicated in left-right axis development. Am J Hum Genet. 1999 Mar; 64(3):712-21.