"Chagas Cardiomyopathy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A disease of the CARDIAC MUSCLE developed subsequent to the initial protozoan infection by TRYPANOSOMA CRUZI. After infection, less than 10% develop acute illness such as MYOCARDITIS (mostly in children). The disease then enters a latent phase without clinical symptoms until about 20 years later. Myocardial symptoms of advanced CHAGAS DISEASE include conduction defects (HEART BLOCK) and CARDIOMEGALY.
| Descriptor ID |
D002598
|
| MeSH Number(s) |
C03.752.300.900.200.190 C14.280.238.190
|
| Concept/Terms |
Chagas Cardiomyopathy- Chagas Cardiomyopathy
- Trypanosomiasis, Cardiovascular
- Cardiovascular Trypanosomiasis
- Chagas' Cardiomyopathy
- Cardiomyopathy, Chagas'
- Cardiomyopathy, Chagas
|
Below are MeSH descriptors whose meaning is more general than "Chagas Cardiomyopathy".
Below are MeSH descriptors whose meaning is more specific than "Chagas Cardiomyopathy".
This graph shows the total number of publications written about "Chagas Cardiomyopathy" by people in this website by year, and whether "Chagas Cardiomyopathy" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 4 | 1 | 5 |
| 2015 | 2 | 0 | 2 |
| 2016 | 0 | 1 | 1 |
| 2017 | 2 | 0 | 2 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 0 | 1 | 1 |
| 2021 | 3 | 0 | 3 |
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Below are the most recent publications written about "Chagas Cardiomyopathy" by people in Profiles.
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Signal Transducer and Activator of Transcription-3 Modulation of Cardiac Pathology in Chronic Chagasic Cardiomyopathy. Front Cell Infect Microbiol. 2021; 11:708325.
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Alterations to the Cardiac Metabolome Induced by Chronic T. cruzi Infection Relate to the Degree of Cardiac Pathology. ACS Infect Dis. 2021 06 11; 7(6):1638-1649.
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Autoantibodies against the immunodominant sCha epitope discriminate the risk of sudden death in chronic Chagas cardiomyopathy. Ann N Y Acad Sci. 2021 08; 1497(1):27-38.
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COVID-19: Implications for People with Chagas Disease. Glob Heart. 2020 Oct 13; 15(1):69.
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Improved Biomarker and Imaging Analysis for Characterizing Progressive Cardiac Fibrosis in a Mouse Model of Chronic Chagasic Cardiomyopathy. J Am Heart Assoc. 2019 11 19; 8(22):e013365.
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A therapeutic vaccine prototype induces protective immunity and reduces cardiac fibrosis in a mouse model of chronic Trypanosoma cruzi infection. PLoS Negl Trop Dis. 2019 05; 13(5):e0007413.
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Vaccine-Linked Chemotherapy Improves Benznidazole Efficacy for Acute Chagas Disease. Infect Immun. 2018 04; 86(4).
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Pentose Phosphate Shunt Modulates Reactive Oxygen Species and Nitric Oxide Production Controlling Trypanosoma cruzi in Macrophages. Front Immunol. 2018; 9:202.
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Genetic Adjuvantation of a Cell-Based Therapeutic Vaccine for Amelioration of Chagasic Cardiomyopathy. Infect Immun. 2017 09; 85(9).
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Molecular identification and genotyping of Trypanosoma cruzi DNA in autochthonous Chagas disease patients from Texas, USA. Infect Genet Evol. 2017 04; 49:151-156.