Depressive Disorder, Major
"Depressive Disorder, Major" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Marked depression appearing in the involution period and characterized by hallucinations, delusions, paranoia, and agitation.
| Descriptor ID |
D003865
|
| MeSH Number(s) |
F03.600.300.375
|
| Concept/Terms |
Depressive Disorder, Major- Depressive Disorder, Major
- Depressive Disorders, Major
- Disorder, Major Depressive
- Disorders, Major Depressive
- Major Depressive Disorders
- Major Depressive Disorder
Paraphrenia, Involutional- Paraphrenia, Involutional
- Involutional Paraphrenia
- Involutional Paraphrenias
- Paraphrenias, Involutional
Depression, Involutional- Depression, Involutional
- Involutional Depression
- Melancholia, Involutional
- Involutional Melancholia
|
Below are MeSH descriptors whose meaning is more general than "Depressive Disorder, Major".
Below are MeSH descriptors whose meaning is more specific than "Depressive Disorder, Major".
This graph shows the total number of publications written about "Depressive Disorder, Major" by people in this website by year, and whether "Depressive Disorder, Major" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 2 | 0 | 2 |
| 2001 | 2 | 0 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 2 | 6 |
| 2004 | 6 | 1 | 7 |
| 2005 | 5 | 2 | 7 |
| 2006 | 4 | 1 | 5 |
| 2007 | 1 | 1 | 2 |
| 2008 | 11 | 3 | 14 |
| 2009 | 8 | 3 | 11 |
| 2010 | 5 | 3 | 8 |
| 2011 | 5 | 0 | 5 |
| 2012 | 4 | 1 | 5 |
| 2013 | 4 | 1 | 5 |
| 2014 | 13 | 0 | 13 |
| 2015 | 9 | 2 | 11 |
| 2016 | 14 | 1 | 15 |
| 2017 | 18 | 3 | 21 |
| 2018 | 14 | 3 | 17 |
| 2019 | 17 | 4 | 21 |
| 2020 | 19 | 1 | 20 |
| 2021 | 16 | 1 | 17 |
| 2022 | 15 | 0 | 15 |
| 2023 | 15 | 1 | 16 |
| 2024 | 11 | 3 | 14 |
| 2025 | 4 | 1 | 5 |
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Below are the most recent publications written about "Depressive Disorder, Major" by people in Profiles.
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Functional connectome-based predictive modeling of suicidal ideation. J Affect Disord. 2025 Oct 15; 387:119518.
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Azetukalner, a Novel KV7 Potassium Channel Opener, in Adults With Major Depressive Disorder: A Randomized Clinical Trial. JAMA Netw Open. 2025 May 01; 8(5):e2514278.
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Navacaprant, a Novel and Highly Selective Kappa Opioid Receptor Antagonist, in Adults With Major Depressive Disorder: A Randomized, Double-Blind Phase 2 Clinical Trial. J Clin Psychopharmacol. 2025 May-Jun 01; 45(3):267-276.
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The real-world impact of cariprazine on short- and long-term disability outcomes among commercially insured patients in the United States. J Med Econ. 2025 Dec; 28(1):335-345.
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Long-Term Safety and Efficacy of Esmethadone in Patients With Major Depressive Disorder: Findings From a 12-Month Open-Label Study. J Clin Psychiatry. 2025 Feb 17; 86(1).
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Efficacy and safety of psilocybin in the treatment of Major Depressive Disorder (MDD): A dose-response network meta-analysis of randomized placebo-controlled clinical trials. Psychiatry Res. 2025 Feb; 344:116337.
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Effects of Varenicline, Bupropion, Nicotine Patch, and Placebo on Treating Smoking Among Persons With Current or Past Major Depressive Disorder: Secondary Analysis of a Double-Blind, Randomized, Placebo-Controlled Trial. Am J Psychiatry. 2025 Feb 01; 182(2):174-186.
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Aperiodic (1/f) Neural Activity Robustly Tracks Symptom Severity Changes in Treatment-Resistant Depression. Biol Psychiatry Cogn Neurosci Neuroimaging. 2025 Feb; 10(2):186-194.
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Transcranial Direct Current Stimulation Combined With Repetitive Transcranial Magnetic Stimulation for Depression: A Randomized Clinical Trial. JAMA Netw Open. 2024 Nov 04; 7(11):e2444306.
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Efficacy of Deep Brain Stimulation for Treatment-Resistant Depression: Systematic Review and Meta-Analysis. Biol Psychiatry Cogn Neurosci Neuroimaging. 2024 Dec; 9(12):1239-1248.