JOSEPH ALGE

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    Collapse Biography 
    Collapse education and training
    Medical University of South CarolinaMD05/2015
    Medical University of South CarolinaMS05/2015Clinical Research
    Medical University of South CarolinaPhD052015
    Baylor College of Medicine07/2018Pediatric Residency
    Baylor College of Medicine07/202Pediatric Nephrology Fellowship
    Collapse awards and honors
    2019 - 2020Adeline B. Landa Fellowship, Texas Children's Hospital
    2018Society for Pediatric Research House Officer Research Award, Baylor College of Medicine
    2016Reba Michels Hill Research Scholarship, Baylor College of Medicine
    2014Alpha Omega Alpha, Medical Honor Society, Medical University of South Carolina

    Collapse Overview 
    Collapse overview
    I am a dual-trained physician-scientist and practicing pediatric nephrologist. My lab uses a ttranslational approach to investigate mechanisms of renal injury and repair with a focus on acute kidney injury and the transition to chronic kidney disease.

    Collapse Research 
    Collapse research activities and funding
    Early Career Award     (Joseph Alge)Mar 1, 2021 - Dec 31, 2021
    Thrasher Research Fund
    Relative Oliguria as a Risk Factor for Volume Overload in Critically Ill Children
    Role Description: The goal of this study is to define the concept of relative oliguria and determine its utility as early and sensitive predictor of volume overload and related morbidity and mortality in critically ill children.
    Role: PI

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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Alge JL, Wenderfer SE. 50 Years Ago in The Journal of Pediatrics: The Hemolytic-Uremic Syndrome: Renal Status of 76 Patients at Long-Term Follow-Up. J Pediatr. 2018 06; 197:185. PMID: 29801537.
      Citations:    Fields:    Translation:Humans
    2. Alge JL, Wenderfer SE, Hicks J, Bekheirnia MR, Schady DA, Kain JS, Braun MC. Hemolytic uremic syndrome as the presenting manifestation of WT1 mutation and Denys-Drash syndrome: a case report. BMC Nephrol. 2017 Jul 18; 18(1):243. PMID: 28720077.
      Citations: 2     Fields:    Translation:Humans
    3. Whitaker RM, Stallons LJ, Kneff JE, Alge JL, Harmon JL, Rahn JJ, Arthur JM, Beeson CC, Chan SL, Schnellmann RG. Urinary mitochondrial DNA is a biomarker of mitochondrial disruption and renal dysfunction in acute kidney injury. Kidney Int. 2015 Dec; 88(6):1336-1344. PMID: 26287315.
      Citations: 26     Fields:    
    4. Alge JL, Arthur JM. Biomarkers of AKI: a review of mechanistic relevance and potential therapeutic implications. Clin J Am Soc Nephrol. 2015 Jan 07; 10(1):147-55. PMID: 25092601.
      Citations: 88     Fields:    Translation:HumansAnimals
    5. Alge JL, Karakala N, Neely BA, Janech MG, Tumlin JA, Chawla LS, Shaw AD, Arthur JM. Association of elevated urinary concentration of renin-angiotensin system components and severe AKI. Clin J Am Soc Nephrol. 2013 Dec; 8(12):2043-52. PMID: 24009222.
      Citations: 11     Fields:    Translation:HumansCells
    6. Arthur JM, Hill EG, Alge JL, Lewis EC, Neely BA, Janech MG, Tumlin JA, Chawla LS, Shaw AD. Evaluation of 32 urine biomarkers to predict the progression of acute kidney injury after cardiac surgery. Kidney Int. 2014 Feb; 85(2):431-8. PMID: 24005224.
      Citations: 45     Fields:    Translation:Humans
    7. Alge JL, Karakala N, Neely BA, Janech MG, Velez JC, Arthur JM. Urinary angiotensinogen predicts adverse outcomes among acute kidney injury patients in the intensive care unit. Crit Care. 2013 Apr 15; 17(2):R69. PMID: 23587112.
      Citations: 10     Fields:    Translation:Humans
    8. Bhensdadia NM, Hunt KJ, Lopes-Virella MF, Michael Tucker J, Mataria MR, Alge JL, Neely BA, Janech MG, Arthur JM. Urine haptoglobin levels predict early renal functional decline in patients with type 2 diabetes. Kidney Int. 2013 Jun; 83(6):1136-43. PMID: 23536133.
      Citations: 20     Fields:    Translation:Humans
    9. Alge JL, Karakala N, Neely BA, Janech MG, Tumlin JA, Chawla LS, Shaw AD, Arthur JM. Urinary angiotensinogen and risk of severe AKI. Clin J Am Soc Nephrol. 2013 Feb; 8(2):184-93. PMID: 23143504.
      Citations: 32     Fields:    Translation:Humans
    10. Korrapati MC, Shaner BE, Neely BA, Alge JL, Arthur JM, Schnellmann RG. Diabetes-induced renal injury in rats is attenuated by suramin. J Pharmacol Exp Ther. 2012 Oct; 343(1):34-43. PMID: 22736507.
      Citations: 10     Fields:    Translation:Animals
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