"Chagas Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.
| Descriptor ID |
D014355
|
| MeSH Number(s) |
C03.752.300.900.200
|
| Concept/Terms |
Chagas Disease- Chagas Disease
- Chagas' Disease
- American Trypanosomiasis
- Trypanosomiasis, American
- Trypanosomiasis, South American
- South American Trypanosomiasis
- Trypanosoma cruzi Infection
- Infection, Trypanosoma cruzi
- Infections, Trypanosoma cruzi
- Trypanosoma cruzi Infections
|
Below are MeSH descriptors whose meaning is more general than "Chagas Disease".
Below are MeSH descriptors whose meaning is more specific than "Chagas Disease".
This graph shows the total number of publications written about "Chagas Disease" by people in this website by year, and whether "Chagas Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 3 | 0 | 3 |
| 2007 | 2 | 0 | 2 |
| 2008 | 2 | 0 | 2 |
| 2009 | 1 | 0 | 1 |
| 2010 | 2 | 1 | 3 |
| 2012 | 4 | 1 | 5 |
| 2013 | 8 | 1 | 9 |
| 2014 | 12 | 1 | 13 |
| 2015 | 8 | 4 | 12 |
| 2016 | 7 | 2 | 9 |
| 2017 | 6 | 3 | 9 |
| 2018 | 11 | 0 | 11 |
| 2019 | 8 | 0 | 8 |
| 2020 | 11 | 1 | 12 |
| 2021 | 8 | 2 | 10 |
| 2022 | 10 | 0 | 10 |
| 2023 | 10 | 0 | 10 |
| 2024 | 10 | 0 | 10 |
| 2025 | 7 | 0 | 7 |
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click here.
Below are the most recent publications written about "Chagas Disease" by people in Profiles.
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Evaluation of a Novel Tc-24 Recombinant Antigen ELISA for Serologic Detection of Trypanosoma cruzi Infection in Dogs: A Pilot Study. Vet Med Sci. 2025 Sep; 11(5):e70570.
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Chagas and Vector-Borne Disease Exposures in an Indigenous Community in the Ecuadorian Amazon: A Retrospective Study. Am J Trop Med Hyg. 2025 Oct 01; 113(4):806-808.
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RNA Sequence Analysis in Macrophages Infected With Trypanosoma cruzi: Focus on TLR2 and TLR7, Iron Metabolism, and Extracellular Matrix Biosynthesis. J Infect Dis. 2025 Jul 11; 231(6):e1102-e1113.
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Rapid High-Sensitivity Detection of Antibodies to Trypanosoma cruzi With a Recombinant Tc24 Antigen-Based Magneto-Immunoassay: A Pilot Study. J Infect Dis. 2025 Jul 11; 231(6):e1114-e1118.
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Different responses involving Tfh cells delay parasite-specific antibody production in Trypanosoma cruzi acute experimental models. Front Immunol. 2025; 16:1487317.
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Coinfection by multiple Trypanosoma cruzi clones: a new perspective on host-parasite relationship with consequences for pathogenesis and management of Chagas disease. Microbiol Mol Biol Rev. 2025 Jun 25; 89(2):e0024224.
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One health research to mitigate health burden of American trypanosomiasis in Mexico. Acta Trop. 2025 Mar; 263:107567.
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Immunopeptidomic MHC-I profiling and immunogenicity testing identifies Tcj2 as a new Chagas disease mRNA vaccine candidate. PLoS Pathog. 2024 Dec; 20(12):e1012764.
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Parasite-microbiota interactions: a pathway to innovative interventions for Chagas disease, leishmaniasis, and ascariasis. Future Microbiol. 2025 Feb; 20(2):149-161.
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Chagas disease in the immunocompromised host. Curr Opin Infect Dis. 2024 Oct 01; 37(5):333-341.