"Hydrazones" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Compounds of the general formula R:N.NR2, as resulting from the action of hydrazines with aldehydes or ketones. (Grant & Hackh's Chemical Dictionary, 5th ed)
| Descriptor ID |
D006835
|
| MeSH Number(s) |
D02.442.288
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Hydrazones".
Below are MeSH descriptors whose meaning is more specific than "Hydrazones".
This graph shows the total number of publications written about "Hydrazones" by people in this website by year, and whether "Hydrazones" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2007 | 1 | 0 | 1 |
| 2011 | 2 | 0 | 2 |
| 2014 | 2 | 0 | 2 |
| 2015 | 3 | 0 | 3 |
| 2016 | 2 | 0 | 2 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 2 | 2 |
| 2021 | 0 | 3 | 3 |
| 2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Hydrazones" by people in Profiles.
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Levosimendan for Diastolic Dysfunction? Cardiovasc Drugs Ther. 2024 Oct; 38(5):1053-1054.
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Unexpected inhibition of the lipid kinase PIKfyve reveals an epistatic role for p38 MAPKs in endolysosomal fission and volume control. Cell Death Dis. 2024 01 22; 15(1):80.
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A novel survivin dimerization inhibitor without a labile hydrazone linker induces spontaneous apoptosis and synergizes with docetaxel in prostate cancer cells. Bioorg Med Chem. 2022 07 01; 65:116761.
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Levosimendan improves the acute course of takotsubo syndrome: a pooled analysis. ESC Heart Fail. 2021 Oct; 8(5):4360-4363.
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Efficacy and safety of levosimendan and dobutamine in heart failure: A systematic review and meta-analysis. Cardiol J. 2021; 28(3):492-493.
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Levosimendan or dobutamine in patients with low cardiac output syndrome: Results from meta-analysis. Int J Cardiol. 2021 06 15; 333:145.
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Synthesis and Identification of a Novel Lead Targeting Survivin Dimerization for Proteasome-Dependent Degradation. J Med Chem. 2020 07 09; 63(13):7243-7251.
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Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis. Nat Commun. 2018 12 07; 9(1):5230.
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Orally active Epac inhibitor reverses mechanical allodynia and loss of intraepidermal nerve fibers in a mouse model of chemotherapy-induced peripheral neuropathy. Pain. 2018 May; 159(5):884-893.
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A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells. Cell Rep. 2017 07 11; 20(2):427-438.