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HEE-JIN JANG

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Surgery
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Espinosa-Carrasco G, Chiu E, Scrivo A, Zumbo P, Dave A, Betel D, Kang SW, Jang HJ, Hellmann MD, Burt BM, Lee HS, Schietinger A. Intratumoral immune triads are required for immunotherapy-mediated elimination of solid tumors. Cancer Cell. 2024 Jul 08; 42(7):1202-1216.e8. PMID: 38906155; PMCID: PMC11413804.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    2. Lin Y, Burt BM, Lee HS, Nguyen TT, Jang HJ, Lee C, Hong W, Ripley RT, Amos CI, Cheng C. Clonal gene signatures predict prognosis in mesothelioma and lung adenocarcinoma. NPJ Precis Oncol. 2024 Feb 23; 8(1):47. PMID: 38396241; PMCID: PMC10891127.
      Citations: 1     
    3. Jeong YS, Eun YG, Lee SH, Kang SH, Yim SY, Kim EH, Noh JK, Sohn BH, Woo SR, Kong M, Nam DH, Jang HJ, Lee HS, Song S, Oh SC, Lee J, Ajani JA, Lee JS. Clinically conserved genomic subtypes of gastric adenocarcinoma. Mol Cancer. 2023 09 06; 22(1):147. PMID: 37674200; PMCID: PMC10481468.
      Citations: 1     Fields:    Translation:HumansCells
    4. Lee HS, Jang HJ, Ramineni M, Wang DY, Ramos D, Choi JM, Splawn T, Espinoza M, Almarez M, Hosey L, Jo E, Hilsenbeck S, Amos CI, Ripley RT, Burt BM. A Phase II Window of Opportunity Study of Neoadjuvant PD-L1 versus PD-L1 plus CTLA-4 Blockade for Patients with Malignant Pleural Mesothelioma. Clin Cancer Res. 2023 02 01; 29(3):548-559. PMID: 36469573; PMCID: PMC9898180.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    5. Nash AM, Aghlara-Fotovat S, Castillio B, Hernandez A, Pugazenthi A, Lee HS, Jang HJ, Nguyen A, Lu A, Burt BM, Ghanta RK, Veiseh O. Activation of Adaptive and Innate Immune Cells via Localized IL2 Cytokine Factories Eradicates Mesothelioma Tumors. Clin Cancer Res. 2022 12 01; 28(23):5121-5135. PMID: 35993913; PMCID: PMC9713361.
      Citations:    
    6. Jang HJ, Lee HS, Yu W, Ramineni M, Truong CY, Ramos D, Splawn T, Choi JM, Jung SY, Lee JS, Wang DY, Sederstrom JM, Pietropaolo M, Kheradmand F, Amos CI, Wheeler TM, Ripley RT, Burt BM. Therapeutic Targeting of Macrophage Plasticity Remodels the Tumor-Immune Microenvironment. Cancer Res. 2022 07 18; 82(14):2593-2609. PMID: 35709756; PMCID: PMC9296613.
      Citations:    Fields:    Translation:HumansCells
    7. Lee SH, Yim SY, Jeong YS, Li QX, Kang SH, Sohn BH, Kumar SV, Shin JH, Choi YR, Shim JJ, Kim H, Kim JH, Kim S, Guo S, Johnson RL, Kaseb A, Kang KJ, Chun YS, Jang HJ, Lee BG, Woo HG, Ha MJ, Akbani R, Roberts LR, Wheeler DA, Lee JS. Consensus subtypes of hepatocellular carcinoma associated with clinical outcomes and genomic phenotypes. Hepatology. 2022 12; 76(6):1634-1648. PMID: 35349735; PMCID: PMC9519807.
      Citations:    Fields:    
    8. Lee SH, Jeong YS, Lee S, Sohn BH, Cheong JH, Jang HJ, Kaseb A, Roberts L, Yim SY, Chun YS, Lee JS, Hwang HK, Choi GH, Kang CM, Choi JS, Lee WJ. Two distinct stem cell-like subtypes of hepatocellular carcinoma with clinical significance and their therapeutic potentials. Cancer Commun (Lond). 2022 02; 42(2):179-183. PMID: 35032367; PMCID: PMC8822477.
      Citations:    Fields:    Translation:HumansCells
    9. Jang HJ, Truong CY, Lo EM, Holmes HM, Ramos D, Ramineni M, Lee JS, Wang DY, Pietropaolo M, Ripley RT, Burt BM, Lee HS. Inhibition of Cyclin Dependent Kinase 4/6 Overcomes Primary Resistance to Programmed Cell Death 1 Blockade in Malignant Mesothelioma. Ann Thorac Surg. 2022 11; 114(5):1842-1852. PMID: 34592265; PMCID: PMC8957629.
      Citations: 1     Fields:    
    10. Palivela N, Lee HS, Jang HJ, Paily P, Montero M, Najafi B, Burt BM. Improvement of Disability in Neurogenic Thoracic Outlet Syndrome by Robotic First Rib Resection. Ann Thorac Surg. 2022 09; 114(3):919-925. PMID: 34419432.
      Citations: 2     Fields:    
    11. Seo JW, Kim SE, Choi EY, Hong KS, Oh TH, Kim UJ, Kang SJ, Park KH, Jung SI, Kim DY, Yun NR, Kim DM, Kim HP, Hur J, Jang HC. Risk Factors and a Scoring System to Predict ARDS in Patients with COVID-19 Pneumonia in Korea: A Multicenter Cohort Study. Dis Markers. 2021; 2021:8821697. PMID: 33897912; PMCID: PMC8052177.
      Citations:    
    12. Lee HS, Hamaji M, Palivela N, Jang HJ, Splawn T, Ramos D, Lee AK, Raghuram AC, Ramineni M, Amos CI, Ripley RT, Burt BM. Prognostic Role of Programmed Cell Death 1 Ligand 1 in Resectable Pleural Mesothelioma. Ann Thorac Surg. 2021 11; 112(5):1575-1583. PMID: 33248997.
      Citations:    Fields:    Translation:Humans
    13. Kim HK, Choi SM, Kang G, Park KH, Lee DG, Park WB, Rhee SJ, Lee S, Jung SI, Jang HC. Comparison of In Vivo Pharmacokinetics and Pharmacodynamics of Vancomycin Products Available in Korea. Yonsei Med J. 2020 Apr; 61(4):301-309. PMID: 32233172; PMCID: PMC7105400.
      Citations:    
    14. Im WR, Lee HS, Lee YS, Lee JS, Jang HJ, Kim SY, Park JL, Lee Y, Kim MS, Lee JM, Kim IH, Jeon SH, Lee YS. A Regulatory Noncoding RNA, nc886, Suppresses Esophageal Cancer by Inhibiting the AKT Pathway and Cell Cycle Progression. Cells. 2020 03 26; 9(4). PMID: 32225025; PMCID: PMC7226379.
      Citations:    
    15. Jang HJ, Lee HS, Ramos D, Park IK, Kang CH, Burt BM, Kim YT. Transcriptome-based molecular subtyping of non-small cell lung cancer may predict response to immune checkpoint inhibitors. J Thorac Cardiovasc Surg. 2020 04; 159(4):1598-1610.e3. PMID: 31879171.
      Citations: 9     Fields:    Translation:HumansCells
    16. Kim SE, Shin SU, Oh TH, Kim UJ, Darboe KS, Kang SJ, Jang HC, Jung SI, Shin HY, Park KH. Outcomes of Third-Generation Cephalosporin Plus Ciprofloxacin or Doxycycline Therapy in Patients with Vibrio vulnificus Septicemia: A Propensity Score-Matched Analysis. PLoS Negl Trop Dis. 2019 06; 13(6):e0007478. PMID: 31188821; PMCID: PMC6590838.
      Citations:    
    17. Choi WS, Choi JH, Jung DS, Choi HJ, Kim YS, Lee J, Jang HC, Shin EC, Park JS, Kim H, Cheong HJ. Immunogenicity and safety of a new live attenuated herpes zoster vaccine (NBP608) compared to Zostavax? in healthy adults aged 50 years and older. Vaccine. 2019 06 12; 37(27):3605-3610. PMID: 31122860.
      Citations: 1     Fields:    Translation:Humans
    18. Lee HS, Jang HJ, Lo EM, Truong CY, Groth SS, Friedberg JS, Sugarbaker DJ, Burt BM. Povidone-iodine results in rapid killing of thymic epithelial tumour cells through cellular fixation?. Interact Cardiovasc Thorac Surg. 2019 03 01; 28(3):353-359. PMID: 30165653; PMCID: PMC6398267.
      Citations: 6     Fields:    Translation:HumansCells
    19. Oh SC, Sohn BH, Cheong JH, Kim SB, Lee JE, Park KC, Lee SH, Park JL, Park YY, Lee HS, Jang HJ, Park ES, Kim SC, Heo J, Chu IS, Jang YJ, Mok YJ, Jung W, Kim BH, Kim A, Cho JY, Lim JY, Hayashi Y, Song S, Elimova E, Estralla JS, Lee JH, Bhutani MS, Lu Y, Liu W, Lee J, Kang WK, Kim S, Noh SH, Mills GB, Kim SY, Ajani JA, Lee JS. Clinical and genomic landscape of gastric cancer with a mesenchymal phenotype. Nat Commun. 2018 05 03; 9(1):1777. PMID: 29725014; PMCID: PMC5934392.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    20. Lee HS, Jang HJ, Choi JM, Zhang J, de Rosen VL, Wheeler TM, Lee JS, Tu T, Jindra PT, Kerman RH, Jung SY, Kheradmand F, Sugarbaker DJ, Burt BM. Comprehensive immunoproteogenomic analyses of malignant pleural mesothelioma. JCI Insight. 2018 04 05; 3(7). PMID: 29618661; PMCID: PMC5928857.
      Citations: 14     Fields:    Translation:HumansCells
    21. . Single missense mutation as a signal of indolent thymic epithelial tumors: General Transcription Factor II-I (GTF2I). Mediastinum. 2017; 1:20.
    22. Ock CY, Hwang JE, Keam B, Kim SB, Shim JJ, Jang HJ, Park S, Sohn BH, Cha M, Ajani JA, Kopetz S, Lee KW, Kim TM, Heo DS, Lee JS. Genomic landscape associated with potential response to anti-CTLA-4 treatment in cancers. Nat Commun. 2017 10 19; 8(1):1050. PMID: 29051489; PMCID: PMC5648801.
      Citations: 57     Fields:    Translation:HumansAnimals
    23. Yoon D, Shin SH, Jang HC, Kim ES, Song EH, Moon SM, Shin SY, Choe PG, Sung JJ, Choi EH, Oh MD, Jee Y, Kim NJ. Epidemiology and Clinical Characteristics of Zika Virus Infections Imported into Korea from March to October 2016. J Korean Med Sci. 2017 Sep; 32(9):1440-1444. PMID: 28776338; PMCID: PMC5546962.
      Citations: 1     Fields:    Translation:HumansCells
    24. Sohn BH, Hwang JE, Jang HJ, Lee HS, Oh SC, Shim JJ, Lee KW, Kim EH, Yim SY, Lee SH, Cheong JH, Jeong W, Cho JY, Kim J, Chae J, Lee J, Kang WK, Kim S, Noh SH, Ajani JA, Lee JS. Clinical Significance of Four Molecular Subtypes of Gastric Cancer Identified by The Cancer Genome Atlas Project. Clin Cancer Res. 2017 Aug 01; 23(15):4441-4449. PMID: 28747339; PMCID: PMC5785562.
      Citations: 136     Fields:    
    25. Kang SJ, Kim SE, Kim UJ, Jang HC, Park KH, Shin JH, Jung SI. Clinical characteristics and risk factors for mortality in adult patients with persistent candidemia. J Infect. 2017 09; 75(3):246-253. PMID: 28587831.
      Citations:    
    26. Lee HS, Jang HJ, Shah R, Yoon D, Hamaji M, Wald O, Lee JS, Sugarbaker DJ, Burt BM. Genomic Analysis of Thymic Epithelial Tumors Identifies Novel Subtypes Associated with Distinct Clinical Features. Clin Cancer Res. 2017 Aug 15; 23(16):4855-4864. PMID: 28400429; PMCID: PMC5559309.
      Citations: 13     Fields:    Translation:Humans
    27. Cancer Genome Atlas Research Network, Analysis Working Group: Asan University, BC Cancer Agency, Brigham and Women’s Hospital, Broad Institute, Brown University, Case Western Reserve University, Dana-Farber Cancer Institute, Duke University, Greater Poland Cancer Centre, KU Leuven, Mayo Clinic, Memorial Sloan Kettering Cancer Center, National Cancer Institute, Nationwide Children’s Hospital, Stanford University, University of Alabama, University of Michigan, University of North Carolina, University of Pittsburgh, University of Rochester, University of Southern California, University of Texas MD Anderson Cancer Center, University of Washington, Vanderbilt University, Washington University, Genome Sequencing Center: Broad Institute, Washington University in St. Louis, Genome Characterization Centers: BC Cancer Agency, Harvard Medical School, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins University, University of North Carolina, University of Southern California Epigenome Center, University of Texas MD Anderson Cancer Center, Van Andel Research Institute, Genome Data Analysis Centers: Broad Institute, Brown University:, Harvard Medical School, Institute for Systems Biology, University of California Santa Cruz, Biospecimen Core Resource: International Genomics Consortium, Research Institute at Nationwide Children’s Hospital, Tissue Source Sites: Analytic Biologic Services, Asan Medical Center, Asterand Bioscience, Barretos Cancer Hospital, BioreclamationIVT, Botkin Municipal Clinic, Chonnam National University Medical School, Christiana Care Health System, Cureline, Duke University, Emory University, Erasmus University, Indiana University School of Medicine, Institute of Oncology of Moldova, International Genomics Consortium, Invidumed, Israelitisches Krankenhaus Hamburg, Keimyung University School of Medicine, Memorial Sloan Kettering Cancer Center, National Cancer Center Goyang, Ontario Tumour Bank, Peter MacCallum Cancer Centre, Pusan National University Medical School, Ribeirão Preto Medical School, St. Joseph’s Hospital &Medical Center, St. Petersburg Academic University, Tayside Tissue Bank, University of Dundee, University of Kansas Medical Center, University of Michigan, University of North Carolina at Chapel Hill, University of Pittsburgh School of Medicine, University of Texas MD Anderson Cancer Center, Disease Working Group: Duke University, Memorial Sloan Kettering Cancer Center, National Cancer Institute, University of Texas MD Anderson Cancer Center, Yonsei University College of Medicine, Data Coordination Center: CSRA Inc., Project Team: National Institutes of Health, Brigham and Women?s Hospital, Nationwide Children?s Hospital, Research Institute at Nationwide Children?s Hospital, Ribeir?o Preto Medical School, St. Joseph?s Hospital &Medical Center. Integrated genomic characterization of oesophageal carcinoma. Nature. 2017 01 12; 541(7636):169-175. PMID: 28052061; PMCID: PMC5651175.
      Citations:    
    28. Lee KW, Lee SS, Hwang JE, Jang HJ, Lee HS, Oh SC, Lee SH, Sohn BH, Kim SB, Shim JJ, Jeong W, Cha M, Cheong JH, Cho JY, Lim JY, Park ES, Kim SC, Kang YK, Noh SH, Ajani JA, Lee JS. Development and Validation of a Six-Gene Recurrence Risk Score Assay for Gastric Cancer. Clin Cancer Res. 2016 Dec 15; 22(24):6228-6235. PMID: 27654712; PMCID: PMC5458637.
      Citations: 14     Fields:    Translation:Humans
    29. Jang HJ, Lee HS, Burt BM, Lee GK, Yoon KA, Park YY, Sohn BH, Kim SB, Kim MS, Lee JM, Joo J, Kim SC, Yun JS, Na KJ, Choi YL, Park JL, Kim SY, Lee YS, Han L, Liang H, Mak D, Burks JK, Zo JI, Sugarbaker DJ, Shim YM, Lee JS. Integrated genomic analysis of recurrence-associated small non-coding RNAs in oesophageal cancer. Gut. 2017 02; 66(2):215-225. PMID: 27507904; PMCID: PMC5536177.
      Citations: 21     Fields:    Translation:HumansCells
    30. Park YY, Sohn BH, Johnson RL, Kang MH, Kim SB, Shim JJ, Mangala LS, Kim JH, Yoo JE, Rodriguez-Aguayo C, Pradeep S, Hwang JE, Jang HJ, Lee HS, Rupaimoole R, Lopez-Berestein G, Jeong W, Park IS, Park YN, Sood AK, Mills GB, Lee JS. Yes-associated protein 1 and transcriptional coactivator with PDZ-binding motif activate the mammalian target of rapamycin complex 1 pathway by regulating amino acid transporters in hepatocellular carcinoma. Hepatology. 2016 Jan; 63(1):159-72. PMID: 26389641; PMCID: PMC4881866.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    31. Sohn BH, Shim JJ, Kim SB, Jang KY, Kim SM, Kim JH, Hwang JE, Jang HJ, Lee HS, Kim SC, Jeong W, Kim SS, Park ES, Heo J, Kim YJ, Kim DG, Leem SH, Kaseb A, Hassan MM, Cha M, Chu IS, Johnson RL, Park YY, Lee JS. Inactivation of Hippo Pathway Is Significantly Associated with Poor Prognosis in Hepatocellular Carcinoma. Clin Cancer Res. 2016 Mar 01; 22(5):1256-64. PMID: 26459179; PMCID: PMC5536176.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    32. Kim CJ, Kang SJ, Yoon D, Lee MJ, Kim M, Song KH, Jang HC, Jung SI, Kim ES, Kim HB, Oh MD, Park KH, Kim NJ. Factors influencing culture positivity in pyogenic vertebral osteomyelitis patients with prior antibiotic exposure. Antimicrob Agents Chemother. 2015 Apr; 59(4):2470-3. PMID: 25666156; PMCID: PMC4356833.
      Citations: 6     Fields:    Translation:Humans
    33. Kim JE, Kim UJ, Kim HK, Cho SK, An JH, Kang SJ, Park KH, Jung SI, Jang HC. Predictors of viral pneumonia in patients with community-acquired pneumonia. PLoS One. 2014; 9(12):e114710. PMID: 25531901; PMCID: PMC4273967.
      Citations: 5     Fields:    Translation:HumansCells
    34. Lee KW, Lee SS, Kim SB, Sohn BH, Lee HS, Jang HJ, Park YY, Kopetz S, Kim SS, Oh SC, Lee JS. Significant association of oncogene YAP1 with poor prognosis and cetuximab resistance in colorectal cancer patients. Clin Cancer Res. 2015 Jan 15; 21(2):357-64. PMID: 25388162; PMCID: PMC4513664.
      Citations: 78     Fields:    Translation:HumansCells
    35. Lee HS, Lee K, Jang HJ, Lee GK, Park JL, Kim SY, Kim SB, Johnson BH, Zo JI, Lee JS, Lee YS. Epigenetic silencing of the non-coding RNA nc886 provokes oncogenes during human esophageal tumorigenesis. Oncotarget. 2014 Jun 15; 5(11):3472-81. PMID: 25004084; PMCID: PMC4116496.
      Citations: 38     Fields:    Translation:HumansCells
    36. Jang MO, Jang HC, Kim UJ, Ahn JH, Kang SJ, Jung SI, Shin HY, Park KH. Outcome of intravenous azithromycin therapy in patients with complicated scrub typhus compared with that of doxycycline therapy using propensity-matched analysis. Antimicrob Agents Chemother. 2014; 58(3):1488-93. PMID: 24366734; PMCID: PMC3957884.
      Citations:    
    37. Park SY, Lee HS, Jang HJ, Lee JY, Joo J, Zo JI. The role of one-year endoscopic follow-up for the esophageal remnant and gastric conduit after esophagectomy with gastric reconstruction for esophageal squamous cell carcinoma. Yonsei Med J. 2013 Mar 01; 54(2):381-8. PMID: 23364971; PMCID: PMC3575976.
      Citations:    
    38. Yoon KA, Yoon H, Park S, Jang HJ, Zo JI, Lee HS, Lee JS. The prognostic impact of microRNA sequence polymorphisms on the recurrence of patients with completely resected non-small cell lung cancer. J Thorac Cardiovasc Surg. 2012 Oct; 144(4):794-807. PMID: 22818121.
      Citations:    
    39. Park SY, Lee HS, Jang HJ, Joo J, Zo JI. Efficacy of intraoperative, single-bolus corticosteroid administration to prevent postoperative acute respiratory failure after oesophageal cancer surgery. Interact Cardiovasc Thorac Surg. 2012 Oct; 15(4):639-43. PMID: 22745302; PMCID: PMC3445342.
      Citations:    
    40. Kim SJ, Park SJ, Yu HG, Kim NJ, Jang HC, Oh MD. Ocular manifestations of acquired immunodeficiency syndrome in Korea. J Korean Med Sci. 2012 May; 27(5):542-6. PMID: 22563221; PMCID: PMC3342547.
      Citations:    
    41. Lee HS, Park SY, Jang HJ, Kim MS, Lee JM, Zo JI. Free jejunal graft for esophageal reconstruction using end-to-side vascular anastomosis and extended pharyngo-jejunostomy. Ann Thorac Surg. 2012 Jun; 93(6):1850-4. PMID: 22440367.
      Citations:    
    42. Lee HS, Jang HJ. Thoracoscopic mediastinal lymph node dissection for lung cancer. Semin Thorac Cardiovasc Surg. 2012; 24(2):131-41. PMID: 22920530.
      Citations:    
    43. Park SY, Lee HS, Jang HJ, Joo J, Kim MS, Lee JM, Zo JI. Wedge bronchoplastic lobectomy for non-small cell lung cancer as an alternative to sleeve lobectomy. J Thorac Cardiovasc Surg. 2012 Apr; 143(4):825-831.e3. PMID: 22104687.
      Citations:    
    44. Jang HJ, Lee HS, Park SY, Zo JI. Comparison of the early robot-assisted lobectomy experience to video-assisted thoracic surgery lobectomy for lung cancer: a single-institution case series matching study. Innovations (Phila). 2011 Sep; 6(5):305-10. PMID: 22436706.
      Citations:    
    45. Jang HJ, Lee HS, Kim MS, Lee JM, Zo JI. Patterns of lymph node metastasis and survival for upper esophageal squamous cell carcinoma. Ann Thorac Surg. 2011 Sep; 92(3):1091-7. PMID: 21704967.
      Citations:    
    46. Park SY, Lee HS, Jang HJ, Lee GK, Chung KY, Zo JI. Tumor necrosis as a prognostic factor for stage IA non-small cell lung cancer. Ann Thorac Surg. 2011 Jun; 91(6):1668-73. PMID: 21619963.
      Citations:    
    47. Jang HC, Lee S, Song KH, Jeon JH, Park WB, Park SW, Kim HB, Kim NJ, Kim EC, Oh MD, Choe KW. Clinical features, risk factors and outcomes of bacteremia due to enterococci with high-level gentamicin resistance: comparison with bacteremia due to enterococci without high-level gentamicin resistance. J Korean Med Sci. 2010 Jan; 25(1):3-8. PMID: 20052340; PMCID: PMC2800024.
      Citations: 6     Fields:    Translation:HumansCells
    48. Park KH, Jung SI, Jang HC, Shin JH. First successful puncture, aspiration, injection, and re-aspiration of hydatid cyst in the liver presenting with anaphylactic shock in Korea. Yonsei Med J. 2009 Oct 31; 50(5):717-20. PMID: 19881979; PMCID: PMC2768250.
      Citations:    
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