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SIYUAN ZHENG

TitleInstructor
InstitutionMD Anderson
DepartmentGenomic Medicine
Address1515 Holcombe Blvd.
Houston TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Miao ZW, Wang Z, Zheng SL, Wang SN, Miao CY. Anti-stroke biologics: from recombinant proteins to stem cells and organoids. Stroke Vasc Neurol. 2024 Jan 29. PMID: 38286483.
      Citations: 1     Fields:    
    2. Xu Y, Nipper MH, Dominguez AA, Ye Z, Akanuma N, Lopez K, Deng JJ, Arenas D, Sanchez A, Sharkey FE, Court CM, Singhi AD, Wang H, Fernandez-Zapico ME, Sun LZ, Zheng S, Chen Y, Liu J, Wang P. Reconstitution of human PDAC using primary cells reveals oncogenic transcriptomic features at tumor onset. Nat Commun. 2024 Jan 27; 15(1):818. PMID: 38280869; PMCID: PMC10821902.
      Citations:    Fields:    Translation:HumansAnimalsCells
    3. Miao ZW, Wang N, Hu WJ, Zheng SL, Wang DS, Chang FQ, Wang Z, Tian JS, Dong XH, Wu T, Miao CY. Chronic vascular pathogenesis results in the reduced serum Metrnl levels in ischemic stroke patients. Acta Pharmacol Sin. 2024 Jan 22. PMID: 38253637.
      Citations:    Fields:    
    4. He F, Bandyopadhyay AM, Klesse LJ, Rogojina A, Chun SH, Butler E, Hartshorne T, Holland T, Garcia D, Weldon K, Prado LP, Langevin AM, Grimes AC, Sugalski A, Shah S, Assanasen C, Lai Z, Zou Y, Kurmashev D, Xu L, Xie Y, Chen Y, Wang X, Tomlinson GE, Skapek SX, Houghton PJ, Kurmasheva RT, Zheng S. Genomic profiling of subcutaneous patient-derived xenografts reveals immune constraints on tumor evolution in childhood solid cancer. Nat Commun. 2023 Nov 22; 14(1):7600. PMID: 37990009; PMCID: PMC10663468.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Alejo S, Palacios BE, Venkata PP, He Y, Li W, Johnson JD, Chen Y, Jayamohan S, Pratap UP, Clarke K, Zou Y, Lv Y, Weldon K, Viswanadhapalli S, Lai Z, Ye Z, Chen Y, Gilbert AR, Suzuki T, Tekmal RR, Zhao W, Zheng S, Vadlamudi RK, Brenner AJ, Sareddy GR. Lysine-specific histone demethylase 1A (KDM1A/LSD1) inhibition attenuates DNA double-strand break repair and augments the efficacy of temozolomide in glioblastoma. Neuro Oncol. 2023 07 06; 25(7):1249-1261. PMID: 36652263; PMCID: PMC10326496.
      Citations: 1     Fields:    Translation:AnimalsCells
    6. Shapiro JA, Gaonkar KS, Spielman SJ, Savonen CL, Bethell CJ, Jin R, Rathi KS, Zhu Y, Egolf LE, Farrow BK, Miller DP, Yang Y, Koganti T, Noureen N, Koptyra MP, Duong N, Santi M, Kim J, Robins S, Storm PB, Mack SC, Lilly JV, Xie HM, Jain P, Raman P, Rood BR, Lulla RR, Nazarian J, Kraya AA, Vaksman Z, Heath AP, Kline C, Scolaro L, Viaene AN, Huang X, Way GP, Foltz SM, Zhang B, Poetsch AR, Mueller S, Ennis BM, Prados M, Diskin SJ, Zheng S, Guo Y, Kannan S, Waanders AJ, Margol AS, Kim MC, Hanson D, Van Kuren N, Wong J, Kaufman RS, Coleman N, Blackden C, Cole KA, Mason JL, Madsen PJ, Koschmann CJ, Stewart DR, Wafula E, Brown MA, Resnick AC, Greene CS, Rokita JL, Taroni JN, Children?s Brain Tumor Network, Pacific Pediatric Neuro-Oncology Consortium. OpenPBTA: The Open Pediatric Brain Tumor Atlas. Cell Genom. 2023 Jul 12; 3(7):100340. PMID: 37492101; PMCID: PMC10363844.
      Citations: 5     
    7. Xu TY, Qing SL, Zhao JX, Song J, Miao ZW, Li JX, Yang FY, Zhao HY, Zheng SL, Li ZY, Wang SN, Miao CY. Metrnl deficiency retards skin wound healing in mice by inhibiting AKT/eNOS signaling and angiogenesis. Acta Pharmacol Sin. 2023 Sep; 44(9):1790-1800. PMID: 37142683; PMCID: PMC10462726.
      Citations:    
    8. Wu M, Wu L, Wu W, Zhu M, Li J, Wang Z, Li J, Ding R, Liang Y, Li L, Zhang T, Huang B, Cai Y, Li K, Li L, Zhang R, Hu B, Lin F, Wang X, Zheng S, Chen J, You Y, Jiang T, Zhang J, Chen H, Wang Q. Phagocytosis of Glioma Cells Enhances the Immunosuppressive Phenotype of Bone Marrow-Derived Macrophages. Cancer Res. 2023 03 02; 83(5):771-785. PMID: 36622331; PMCID: PMC9978884.
      Citations: 1     Fields:    Translation:HumansCells
    9. Wu L, Wu W, Zhang J, Zhao Z, Li L, Zhu M, Wu M, Wu F, Zhou F, Du Y, Chai RC, Zhang W, Qiu X, Liu Q, Wang Z, Li J, Li K, Chen A, Jiang Y, Xiao X, Zou H, Srivastava R, Zhang T, Cai Y, Liang Y, Huang B, Zhang R, Lin F, Hu L, Wang X, Qian X, Lv S, Hu B, Zheng S, Hu Z, Shen H, You Y, Verhaak RGW, Jiang T, Wang Q. Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma. Cancer Discov. 2022 Dec 02; 12(12):2820-2837. PMID: 36122307.
      Citations:    
    10. Wang X, Langevin AM, Houghton PJ, Zheng S. Genomic disparities between cancers in adolescent and young adults and in older adults. Nat Commun. 2022 Nov 24; 13(1):7223. PMID: 36433963.
      Citations:    Fields:    Translation:Humans
    11. Noureen N, Wang X, Zheng S. Protocol to benchmark gene expression signature scoring techniques for single-cell RNA sequencing data in cancer. STAR Protoc. 2022 Dec 16; 3(4):101877. PMID: 36595948.
      Citations:    Fields:    
    12. Hong C, Wang Z, Zheng SL, Hu WJ, Wang SN, Zhao Y, Miao CY. Metrnl regulates cognitive dysfunction and hippocampal BDNF levels in D-galactose-induced aging mice. Acta Pharmacol Sin. 2023 Apr; 44(4):741-751. PMID: 36229598; PMCID: PMC10042843.
      Citations:    
    13. Noureen N, Ye Z, Chen Y, Wang X, Zheng S. Signature-scoring methods developed for bulk samples are not adequate for cancer single-cell RNA sequencing data. Elife. 2022 02 25; 11. PMID: 35212622; PMCID: PMC8916770.
      Citations: 1     Fields:    Translation:HumansCells
    14. Wang L, Hensch NR, Bondra K, Sreenivas P, Zhao XR, Chen J, Moreno Campos R, Baxi K, Vaseva AV, Sunkel BD, Gryder BE, Stanton BZ, Zheng S, Chen EY, Khan J, Houghton PJ, Ignatius MS, Pomella S, Rota R. SNAI2-Mediated Repression of BIM Protects Rhabdomyosarcoma from Ionizing Radiation. Cancer Res. 2021 11 01; 81(21):5451-5463. PMID: 34462275; PMCID: PMC8669772.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    15. Paull EO, Aytes A, Jones SJ, Subramaniam PS, Giorgi FM, Douglass EF, Tagore S, Chu B, Vasciaveo A, Zheng S, Verhaak R, Abate-Shen C, Alvarez MJ, Califano A. A modular master regulator landscape controls cancer transcriptional identity. Cell. 2021 01 21; 184(2):334-351.e20. PMID: 33434495; PMCID: PMC8103356.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    16. Yang J, Li Q, Noureen N, Fang Y, Kurmasheva R, Houghton PJ, Wang X, Zheng S. PCAT: an integrated portal for genomic and preclinical testing data of pediatric cancer patient-derived xenograft models. Nucleic Acids Res. 2021 01 08; 49(D1):D1321-D1327. PMID: 32810235; PMCID: PMC7778893.
      Citations:    Fields:    Translation:HumansAnimals
    17. Noureen N, Wu S, Lv Y, Yang J, Alfred Yung WK, Gelfond J, Wang X, Koul D, Ludlow A, Zheng S. Integrated analysis of telomerase enzymatic activity unravels an association with cancer stemness and proliferation. Nat Commun. 2021 01 08; 12(1):139. PMID: 33420056; PMCID: PMC7794223.
      Citations: 8     Fields:    Translation:HumansCells
    18. Li Y, Li B, Li W, Wang Y, Treisman DM, Heist KA, Pierce BR, Hoff B, Ho CY, Ferguson DO, Rehemtulla A, Zheng S, Ross BD, Li JZ, Zhu Y, Akg?l S. Murine models of IDH-wild-type glioblastoma exhibit spatial segregation of tumor initiation and manifestation during evolution. Nat Commun. 2020 07 22; 11(1):3669. PMID: 32699356; PMCID: PMC7376246.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    19. Qiu Z, Lin AP, Jiang S, Elkashef SM, Myers J, Srikantan S, Sasi B, Cao JZ, Godley LA, Rakheja D, Lyu Y, Zheng S, Madesh M, Shiio Y, Dahia PLM, Aguiar RCT. MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome. Cell Chem Biol. 2020 05 21; 27(5):538-550.e7. PMID: 32101699; PMCID: PMC7714266.
      Citations:    
    20. Ghilu S, Li Q, Fontaine SD, Santi DV, Kurmasheva RT, Zheng S, Houghton PJ. Prospective use of the single-mouse experimental design for the evaluation of PLX038A. Cancer Chemother Pharmacol. 2020 02; 85(2):251-263. PMID: 31927611; PMCID: PMC7039322.
      Citations: 7     Fields:    Translation:AnimalsCells
    21. Wu S, Gao F, Zheng S, Zhang C, Martinez-Ledesma E, Ezhilarasan R, Ding J, Li X, Feng N, Multani A, Sulman EP, Verhaak RG, de Groot JF, Heffernan TP, Yung WKA, Koul D. EGFR Amplification Induces Increased DNA Damage Response and Renders Selective Sensitivity to Talazoparib (PARP Inhibitor) in Glioblastoma. Clin Cancer Res. 2020 03 15; 26(6):1395-1407. PMID: 31852834.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    22. Rokita JL, Rathi KS, Cardenas MF, Upton KA, Jayaseelan J, Cross KL, Pfeil J, Egolf LE, Way GP, Farrel A, Kendsersky NM, Patel K, Gaonkar KS, Modi A, Berko ER, Lopez G, Vaksman Z, Mayoh C, Nance J, McCoy K, Haber M, Evans K, McCalmont H, Bendak K, Marshall GM, Tyrrell V, Kalletla K, Braun FK, Qi L, Du Y, Zhang H, Lindsay HB, Zhao S, Shu J, Baxter P, Morton C, Kurmashev D, Zheng S, Chen Y, Bowen J, Bryan AC, Leraas KM, Coppens SE, Doddapaneni H, Momin Z, Zhang W, Sacks GI, Hart LS, Krytska K, Mosse YP, Gatto GJ, Sanchez Y, Greene CS, Diskin SJ, Vaske OM, Haussler D, Gastier-Foster JM, Kolb EA, Gorlick R, Li XN, Reynolds CP, Kurmasheva RT, Houghton PJ, Smith MA, Lock RB, Raman P, Wheeler DA, Maris JM, B?hm JW. Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to Enable Rational Clinical Trial Design. Cell Rep. 2019 11 05; 29(6):1675-1689.e9. PMID: 31693904; PMCID: PMC6880934.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    23. Tanabe A, Sakurai A, Nakai T, Zethoven M, Balachander S, Aita Y, Young W, Takekoshi K, Tothill RW, Flores SK, Cheng Z, Jasper AM, Natori K, Okamoto T, Gotoh K, Shibata H, Wang X, Zheng S, Nakamura E, Aguiar RCT, Dahia PLM. Synonymous but Not Silent: A Synonymous VHL Variant in Exon 2 Confers Susceptibility to Familial Pheochromocytoma and von Hippel-Lindau Disease. J Clin Endocrinol Metab. 2019 Sep 01; 104(9):3826-3834. PMID: 30946460; PMCID: PMC6660912.
      Citations: 7     Fields:    
    24. Li X, Martinez-Ledesma E, Zhang C, Gao F, Zheng S, Ding J, Wu S, Nguyen N, Clifford SC, Wen PY, Ligon KL, Yung WKA, Koul D. Tie2-FGFR1 Interaction Induces Adaptive PI3K Inhibitor Resistance by Upregulating Aurora A/PLK1/CDK1 Signaling in Glioblastoma. Cancer Res. 2019 10 01; 79(19):5088-5101. PMID: 31416846.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    25. Zheng S, Alfaro-Munoz K, Wei W, Wang X, Wang F, Eterovic AK, Shaw KRM, Meric-Bernstam F, Fuller GN, Chen K, Verhaak RG, Mills GB, Yung WKA, Weathers SP, de Groot JF. Prospective Clinical Sequencing of Adult Glioma. Mol Cancer Ther. 2019 05; 18(5):991-1000. PMID: 30926639; PMCID: PMC6497568.
      Citations: 5     Fields:    Translation:HumansCells
    26. Ferguson SD, Zheng S, Xiu J, Zhou S, Khasraw M, Brastianos PK, Kesari S, Hu J, Rudnick J, Salacz ME, Piccioni D, Huang S, Davies MA, Glitza IC, Heymach JV, Zhang J, Ibrahim NK, DeGroot JF, McCarty J, O'Brien BJ, Sawaya R, Verhaak RGW, Reddy SK, Priebe W, Gatalica Z, Spetzler D, Heimberger AB. Profiles of brain metastases: Prioritization of therapeutic targets. Int J Cancer. 2018 12 01; 143(11):3019-3026. PMID: 29923182; PMCID: PMC6235694.
      Citations: 15     Fields:    Translation:Humans
    27. Li Y, Zheng S, Kool M, Treisman DM, Li C, Wang Y, Ikenoue T, Shen Y, Camelo-Piragua S, Tomasek G, Stark S, Guduguntla V, Gusella JF, Guan KL, Pfister SM, Verhaak RGW, Zhu Y, Akg?l S, Gr?bner S. Opposing Tumor-Promoting and -Suppressive Functions of Rictor/mTORC2 Signaling in Adult Glioma and Pediatric SHH Medulloblastoma. Cell Rep. 2018 07 10; 24(2):463-478.e5. PMID: 29996106; PMCID: PMC6116735.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    28. deCarvalho AC, Kim H, Poisson LM, Winn ME, Mueller C, Cherba D, Koeman J, Seth S, Protopopov A, Felicella M, Zheng S, Multani A, Jiang Y, Zhang J, Nam DH, Petricoin EF, Chin L, Mikkelsen T, Verhaak RGW. Discordant inheritance of chromosomal and extrachromosomal DNA elements contributes to dynamic disease evolution in glioblastoma. Nat Genet. 2018 05; 50(5):708-717. PMID: 29686388; PMCID: PMC5934307.
      Citations: 83     Fields:    Translation:HumansAnimalsCells
    29. Wu S, Wang S, Gao F, Li L, Zheng S, Yung WKA, Koul D. Activation of WEE1 confers resistance to PI3K inhibition in glioblastoma. Neuro Oncol. 2018 01 10; 20(1):78-91. PMID: 29016926; PMCID: PMC5761544.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    30. Wang Q, Hu B, Hu X, Kim H, Squatrito M, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW, Gabriel Sauv? CE. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2018 01 08; 33(1):152. PMID: 29316430; PMCID: PMC5892424.
      Citations: 78     Fields:    
    31. Hu X, Wang Q, Tang M, Barthel F, Amin S, Yoshihara K, Lang FM, Martinez-Ledesma E, Lee SH, Zheng S, Verhaak RGW. TumorFusions: an integrative resource for cancer-associated transcript fusions. Nucleic Acids Res. 2018 01 04; 46(D1):D1144-D1149. PMID: 29099951; PMCID: PMC5753333.
      Citations: 79     Fields:    Translation:Humans
    32. Lee SH, Kim JS, Zheng S, Huse JT, Bae JS, Lee JW, Yoo KH, Koo HH, Kyung S, Park WY, Sung KW. ARID1B alterations identify aggressive tumors in neuroblastoma. Oncotarget. 2017 Jul 11; 8(28):45943-45950. PMID: 28521285; PMCID: PMC5542239.
      Citations: 10     Fields:    Translation:Humans
    33. Wang Q, Hu B, Hu X, Kim H, Scarpace L, deCarvalho AC, Lyu S, Li P, Li Y, Barthel F, Cho HJ, Lin YH, Satani N, Martinez-Ledesma E, Zheng S, Chang E, Olar A, Lan ZD, Finocchiaro G, Phillips JJ, Berger MS, Gabrusiewicz KR, Wang G, Eskilsson E, Hu J, Mikkelsen T, DePinho RA, Muller F, Heimberger AB, Sulman EP, Nam DH, Verhaak RGW, Squatrito M, Sauv? CG. Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment. Cancer Cell. 2017 07 10; 32(1):42-56.e6. PMID: 28697342; PMCID: PMC5599156.
      Citations: 549     Fields:    Translation:HumansCells
    34. Zheng S. Benchmarking: contexts and details matter. Genome Biol. 2017 07 05; 18(1):129. PMID: 28679434; PMCID: PMC5499005.
      Citations: 2     Fields:    Translation:Humans
    35. Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, Yang JD, Reznik E, Sadeghi S, Pedamallu CS, Ojesina AI, Hess JM, Auman JT, Rhie SK, Bowlby R, Borad MJ, Cancer Genome Atlas Network, Zhu AX, Stuart JM, Sander C, Akbani R, Cherniack AD, Deshpande V, Mounajjed T, Foo WC, Torbenson MS, Kleiner DE, Laird PW, Wheeler DA, McRee AJ, Bathe OF, Andersen JB, Bardeesy N, Roberts LR, Kwong LN. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Rep. 2017 06 27; 19(13):2878-2880. PMID: 28658632; PMCID: PMC6141445.
      Citations: 60     Fields:    
    36. Hu X, Martinez-Ledesma E, Zheng S, Kim H, Barthel F, Jiang T, Hess KR, Verhaak RGW. Multigene signature for predicting prognosis of patients with 1p19q co-deletion diffuse glioma. Neuro Oncol. 2017 06 01; 19(6):786-795. PMID: 28340142; PMCID: PMC5464432.
      Citations: 48     Fields:    Translation:HumansCells
    37. Wang Y, Wu S, Zheng S, Wang S, Wali A, Ezhilarasan R, Sulman EP, Koul D, Alfred Yung WK. APOBEC3G acts as a therapeutic target in mesenchymal gliomas by sensitizing cells to radiation-induced cell death. Oncotarget. 2017 Aug 15; 8(33):54285-54296. PMID: 28903341; PMCID: PMC5589580.
      Citations: 7     Fields:    
    38. Koul D, Wang S, Wu S, Saito N, Zheng S, Gao F, Kaul I, Setoguchi M, Nakayama K, Koyama K, Shiose Y, Sulman EP, Hirota Y, Yung WKA. Preclinical therapeutic efficacy of a novel blood-brain barrier-penetrant dual PI3K/mTOR inhibitor with preferential response in PI3K/PTEN mutant glioma. Oncotarget. 2017 Mar 28; 8(13):21741-21753. PMID: 28423515; PMCID: PMC5400620.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    39. Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, Yang JD, Reznik E, Sadeghi S, Pedamallu CS, Ojesina AI, Hess JM, Auman JT, Rhie SK, Bowlby R, Borad MJ, Cancer Genome Atlas Network, Zhu AX, Stuart JM, Sander C, Akbani R, Cherniack AD, Deshpande V, Mounajjed T, Foo WC, Torbenson MS, Kleiner DE, Laird PW, Wheeler DA, McRee AJ, Bathe OF, Andersen JB, Bardeesy N, Roberts LR, Kwong LN. Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles. Cell Rep. 2017 03 14; 18(11):2780-2794. PMID: 28297679; PMCID: PMC5493145.
      Citations: 155     Fields:    Translation:HumansCells
    40. Shingu T, Ho AL, Yuan L, Zhou X, Dai C, Zheng S, Wang Q, Zhong Y, Chang Q, Horner JW, Liebelt BD, Yao Y, Hu B, Chen Y, Fuller GN, Verhaak RG, Heimberger AB, Hu J. Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation. Nat Genet. 2017 01; 49(1):75-86. PMID: 27841882; PMCID: PMC5453714.
      Citations: 39     Fields:    Translation:AnimalsCells
    41. Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Lerario AM, Else T, Knijnenburg TA, Ciriello G, Kim S, Assie G, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Beuschlein F, Gill AJ, Sidhu SB, Almeida MQ, Fragoso MCBV, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Fassnacht M, Wheeler DA, Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW, Bertherat J. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell. 2016 08 08; 30(2):363. PMID: 27505681.
      Citations: 47     Fields:    
    42. Zheng S, Cherniack AD, Dewal N, Moffitt RA, Danilova L, Murray BA, Else T, Knijnenburg TA, Ciriello G, Kim S, Morozova O, Akbani R, Shih J, Hoadley KA, Choueiri TK, Waldmann J, Mete O, Robertson AG, Wu HT, Raphael BJ, Shao L, Meyerson M, Demeure MJ, Gill AJ, Sidhu SB, Cope LM, Kebebew E, Habra MA, Whitsett TG, Bussey KJ, Rainey WE, Asa SL, Wheeler DA, Cancer Genome Atlas Research Network, Hammer GD, Giordano TJ, Verhaak RGW, Lerario AM, Assie G, Beuschlein F, Almeida MQ, Fragoso MCBV, Bertherat J, Fassnacht M. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell. 2016 05 09; 29(5):723-736. PMID: 27165744; PMCID: PMC4864952.
      Citations: 204     Fields:    Translation:HumansCells
    43. Wu S, Wang S, Zheng S, Verhaak R, Koul D, Yung WK. MSK1-Mediated ?-Catenin Phosphorylation Confers Resistance to PI3K/mTOR Inhibitors in Glioblastoma. Mol Cancer Ther. 2016 07; 15(7):1656-68. PMID: 27196759; PMCID: PMC4936927.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    44. Ceccarelli M, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Zoppoli P, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Mikkelsen T, Lau CC, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Meyerson M, Beroukhim R, Cooper L, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, TCGA Research Network, Iavarone A, Barthel FP, Malta TM, Sabedot TS, Manyam G, Ling S, Carlotti CG, Tirapelli DP, Rao A, Yung WK, Zheng S, Hess K, Rao G, Akbani R, Noushmehr H, Verhaak RG. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 2016 Jan 28; 164(3):550-63. PMID: 26824661; PMCID: PMC4754110.
      Citations: 859     Fields:    Translation:HumansCells
    45. Phan LM, Fuentes-Mattei E, Wu W, Velazquez-Torres G, Sircar K, Wood CG, Hai T, Jimenez C, Cote GJ, Ozsari L, Hofmann MC, Zheng S, Verhaak R, Pagliaro L, Cortez MA, Lee MH, Yeung SC, Habra MA. Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma. Cancer Res. 2015 Oct 01; 75(19):4131-42. PMID: 26282167; PMCID: PMC4592476.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
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      Citations: 1192     Fields:    Translation:HumansCells
    47. Geisenberger C, Mock A, Warta R, Rapp C, Schwager C, Korshunov A, Nied AK, Capper D, Brors B, Jungk C, Jones D, Collins VP, Ichimura K, Schnabel E, Mittelbron M, Lahrmann B, Zheng S, Verhaak RG, Grabe N, Pfister SM, Hartmann C, von Deimling A, Unterberg A, Abdollahi A, Herold-Mende C, B?cklund LM, Debus J. Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain. Acta Neuropathol. 2015 Sep; 130(3):419-34. PMID: 25931051.
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    48. Kim H, Zheng S, Amini SS, Virk SM, Mikkelsen T, Brat DJ, Grimsby J, Sougnez C, Muller F, Hu J, Sloan AE, Cohen ML, Van Meir EG, Scarpace L, Laird PW, Weinstein JN, Lander ES, Gabriel S, Getz G, Meyerson M, Chin L, Barnholtz-Sloan JS, Verhaak RG. Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution. Genome Res. 2015 Mar; 25(3):316-27. PMID: 25650244; PMCID: PMC4352879.
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    49. Han L, Guo Y, Su Z, Zheng S, Lu Z. Advances in computational genomics. Biomed Res Int. 2015; 2015:187803. PMID: 25629039; PMCID: PMC4300036.
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    50. Han L, Yuan Y, Zheng S, Yang Y, Li J, Edgerton ME, Diao L, Xu Y, Verhaak RGW, Liang H. The Pan-Cancer analysis of pseudogene expression reveals biologically and clinically relevant tumour subtypes. Nat Commun. 2014 Jul 07; 5:3963. PMID: 24999802; PMCID: PMC4339277.
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    51. Zheng S, Sivachenko A, Vegesna R, Wang Q, Yao R, Berger MF, Weinstein JN, Getz G, Verhaak RG, Torres-Garc?a W. PRADA: pipeline for RNA sequencing data analysis. Bioinformatics. 2014 Aug 01; 30(15):2224-6. PMID: 24695405; PMCID: PMC4103589.
      Citations: 86     Fields:    Translation:HumansCells
    52. Zheng S, Kim H, Verhaak RGW. Silent mutations make some noise. Cell. 2014 Mar 13; 156(6):1129-1131. PMID: 24630716.
      Citations: 19     Fields:    Translation:HumansCells
    53. Guan X, Vengoechea J, Zheng S, Sloan AE, Chen Y, Brat DJ, O'Neill BP, de Groot J, Yust-Katz S, Yung WK, Cohen ML, Aldape KD, Rosenfeld S, Verhaak RG, Barnholtz-Sloan JS. Molecular subtypes of glioblastoma are relevant to lower grade glioma. PLoS One. 2014; 9(3):e91216. PMID: 24614622; PMCID: PMC3948818.
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    54. Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Lee J, Nishimura R, Sakata N, Carpenter AE, Silver SJ, Verhaak RG, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG, Bilodeau S, Woolard K, Fine HA. ZFHX4 interacts with the NuRD core member CHD4 and regulates the glioblastoma tumor-initiating cell state. Cell Rep. 2014 Jan 30; 6(2):313-24. PMID: 24440720; PMCID: PMC4041390.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    55. Saito N, Fu J, Zheng S, Yao J, Wang S, Liu DD, Yuan Y, Sulman EP, Lang FF, Colman H, Verhaak RG, Yung WK, Koul D. A high Notch pathway activation predicts response to ? secretase inhibitors in proneural subtype of glioma tumor-initiating cells. Stem Cells. 2014 Jan; 32(1):301-12. PMID: 24038660; PMCID: PMC3947402.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    56. Zheng S, Verhaak RG. Intragenic breakpoint: a marker of genome instability in glioblastoma. Cell Cycle. 2013 Dec 15; 12(24):3705-6. PMID: 24145229; PMCID: PMC3905055.
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    57. Brennan CW, Verhaak RG, McKenna A, Campos B, Noushmehr H, Salama SR, Zheng S, Chakravarty D, Sanborn JZ, Berman SH, Beroukhim R, Bernard B, Wu CJ, Genovese G, Shmulevich I, Barnholtz-Sloan J, Zou L, Vegesna R, Shukla SA, Ciriello G, Yung WK, Zhang W, Sougnez C, Mikkelsen T, Aldape K, Bigner DD, Van Meir EG, Prados M, Sloan A, Black KL, Eschbacher J, Finocchiaro G, Friedman W, Andrews DW, Guha A, Iacocca M, O'Neill BP, Foltz G, Myers J, Weisenberger DJ, Penny R, Kucherlapati R, Perou CM, Hayes DN, Gibbs R, Marra M, Mills GB, Lander E, Spellman P, Wilson R, Sander C, Weinstein J, Meyerson M, Gabriel S, Laird PW, Haussler D, Getz G, Chin L, TCGA Research Network. The somatic genomic landscape of glioblastoma. Cell. 2013 Oct 10; 155(2):462-77. PMID: 24120142; PMCID: PMC3910500.
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    58. Cancer Genome Atlas Research Network, Weinstein JN, Collisson EA, Mills GB, Shaw KR, Ozenberger BA, Ellrott K, Shmulevich I, Sander C, Stuart JM. The Cancer Genome Atlas Pan-Cancer analysis project. Nat Genet. 2013 Oct; 45(10):1113-20. PMID: 24071849; PMCID: PMC3919969.
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    59. Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape KD, Sulman EP, Chen K, Koul D, Verhaak RG. A survey of intragenic breakpoints in glioblastoma identifies a distinct subset associated with poor survival. Genes Dev. 2013 Jul 01; 27(13):1462-72. PMID: 23796897; PMCID: PMC3713427.
      Citations: 43     Fields:    Translation:Animals
    60. Zheng S, Chheda MG, Verhaak RG. Studying a complex tumor: potential and pitfalls. Cancer J. 2012 Jan-Feb; 18(1):107-14. PMID: 22290264; PMCID: PMC3342695.
      Citations: 15     Fields:    Translation:Humans
    61. Sun Y, Zheng S, Torossian A, Speirs CK, Schleicher S, Giacalone NJ, Carbone DP, Zhao Z, Lu B. Role of insulin-like growth factor-1 signaling pathway in cisplatin-resistant lung cancer cells. Int J Radiat Oncol Biol Phys. 2012 Mar 01; 82(3):e563-72. PMID: 22197230; PMCID: PMC3271860.
      Citations: 35     Fields:    Translation:HumansAnimalsCells
    62. Simpson DR, Yu M, Zheng S, Zhao Z, Muthuswamy SK, Tansey WP. Epithelial cell organization suppresses Myc function by attenuating Myc expression. Cancer Res. 2011 Jun 01; 71(11):3822-30. PMID: 21610111; PMCID: PMC3347713.
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    63. Bhaskara S, Knutson SK, Jiang G, Chandrasekharan MB, Wilson AJ, Zheng S, Yenamandra A, Locke K, Yuan JL, Bonine-Summers AR, Wells CE, Kaiser JF, Washington MK, Zhao Z, Wagner FF, Sun ZW, Xia F, Holson EB, Khabele D, Hiebert SW. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 2010 Nov 16; 18(5):436-47. PMID: 21075309; PMCID: PMC3004468.
      Citations: 178     Fields:    Translation:HumansAnimalsCells
    64. Jia P, Zheng S, Long J, Zheng W, Zhao Z. dmGWAS: dense module searching for genome-wide association studies in protein-protein interaction networks. Bioinformatics. 2011 Jan 01; 27(1):95-102. PMID: 21045073; PMCID: PMC3008643.
      Citations: 152     Fields:    Translation:Humans
    65. Wang X, Wu D, Zheng S, Sun J, Tao L, Li Y, Cao Z. Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies. BMC Bioinformatics. 2008 Dec 12; 9 Suppl 12:S20. PMID: 19091020; PMCID: PMC2638160.
      Citations: 10     Fields:    Translation:Humans
    66. Li Y, Hao P, Zheng S, Tu K, Fan H, Zhu R, Ding G, Dong C, Wang C, Li X, Thiesen HJ, Chen YE, Jiang H, Liu L, Li Y. Gene expression module-based chemical function similarity search. Nucleic Acids Res. 2008 Nov; 36(20):e137. PMID: 18842630; PMCID: PMC2582597.
      Citations: 12     Fields:    Translation:HumansCells
    67. Zheng S, Sheng J, Wang C, Wang X, Yu Y, Li Y, Michie A, Dai J, Zhong Y, Hao P, Liu L, Li Y. MPSQ: a web tool for protein-state searching. Bioinformatics. 2008 Oct 15; 24(20):2412-3. PMID: 18697766.
      Citations: 3     Fields:    
    68. RETRACTED ARTICLE.
    69. Hepatocyte Growth Factor/cMET Pathway Activation Enhances Cancer Hallmarks in Adrenocortical Carcinoma. Cancer Research. 75:4131-4142.
    70. Molecular subtypes of glioblastoma are relevant to lower grade glioma. PLoS One. 9.
    71. Corrigendum to "3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design" [Biochem. Biophys. Res. Commun. 355 (2007) 513-519] (DOI. Biochemical and Biophysical Research Communications. 384:399.
    72. MSK1-Mediated βb-Catenin Phosphorylation Confers Resistance to PI3K/mTOR Inhibitors in Glioblastoma. Molecular Cancer Therapeutics. 15:1656-1668.
    73. Genome-wide DNA methylation profiling in 40 breast cancer cell lines. 277-284.
    74. Ab-origin. 363-369.
    75. Comprehensive Pan-Genomic Characterization of Adrenocortical Carcinoma. Cancer Cell. 29:723-736.
    76. Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma. Cell. 164:550-563.
    77. Qki deficiency maintains stemness of glioma stem cells in suboptimal environment by downregulating endolysosomal degradation. Nature Genetics. 49:75-86.
    78. Erratum. Cell. 157:753.
    79. Corrigendum to "3D structure modeling of cytochrome P450 2C19 and its implication for personalized drug design" [Biochem. Biophys. Res. Commun. 355 (2007) 513-519] (DOI. Biochemical and Biophysical Research Communications. 357:330.
    80. Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain. Acta Neuropathologica. 130:419-434.
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