 ZAMAL AHMED
| Title | Assistant Professor |
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| Institution | MD Anderson |
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| Department | Molecular & Cellular Oncology |
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| vCard | Download vCard |
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 ORNG Applications Bibliographic
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Bacolla A, Ye Z, Ahmed Z, Tainer JA. Cancer mutational burden is shaped by G4 DNA, replication stress and mitochondrial dysfunction. Prog Biophys Mol Biol. 2019 Mar 14. PMID: 30880007.
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Honda A, Kita T, Seshadri SV, Misaki K, Ahmed Z, Ladbury JE, Richardson GP, Yonemura S, Ladher RK. FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia. Proc Natl Acad Sci U S A. 2018 08 14; 115(33):8388-8393. PMID: 30061390.
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Brosey CA, Ahmed Z, Lees-Miller SP, Tainer JA. What Combined Measurements From Structures and Imaging Tell Us About DNA Damage Responses. Methods Enzymol. 2017; 592:417-455. PMID: 28668129.
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Ahmed Z, Timsah Z, Suen KM, Cook NP, Lee Iv GR, Lin CC, Gagea M, Marti AA, Ladbury JE. Corrigendum: Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. Nat Commun. 2015 Aug 03; 6:8007. PMID: 26234419.
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Ahmed Z, Timsah Z, Suen KM, Cook NP, Lee GR, Lin CC, Gagea M, Marti AA, Ladbury JE. Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. Nat Commun. 2015 Jun 24; 6:7354. PMID: 26103942.
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Bagheri-Yarmand R, Sinha KM, Gururaj AE, Ahmed Z, Rizvi YQ, Huang SC, Ladbury JE, Bogler O, Williams MD, Cote GJ, Gagel RF. A novel dual kinase function of the RET proto-oncogene negatively regulates activating transcription factor 4-mediated apoptosis. J Biol Chem. 2015 May 01; 290(18):11749-61. PMID: 25795775.
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Munoz WA, Lee M, Miller RK, Ahmed Z, Ji H, Link TM, Lee GR, Kloc M, Ladbury JE, McCrea PD. Plakophilin-3 catenin associates with the ETV1/ER81 transcription factor to positively modulate gene activity. PLoS One. 2014; 9(1):e86784. PMID: 24475179.
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Timsah Z, Ahmed Z, Lin CC, Melo FA, Stagg LJ, Leonard PG, Jeyabal P, Berrout J, O'Neil RG, Bogdanov M, Ladbury JE. Competition between Grb2 and Plc?1 for FGFR2 regulates basal phospholipase activity and invasion. Nat Struct Mol Biol. 2014 Feb; 21(2):180-8. PMID: 24440983.
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Cimo AM, Ahmed Z, McIntyre BW, Lewis DE, Ladbury JE. CD25 and CD69 induction by a4ß1 outside-in signalling requires TCR early signalling complex proteins. Biochem J. 2013 Aug 15; 454(1):109-21. PMID: 23758320.
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Suen KM, Lin CC, George R, Melo FA, Biggs ER, Ahmed Z, Drake MN, Arur S, Arold ST, Ladbury JE. Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli. Nat Struct Mol Biol. 2013 May; 20(5):620-7. PMID: 23584453.
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Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE. Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity. J Cell Biol. 2013 Feb 18; 200(4):493-504. PMID: 23420874.
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Lin CC, Melo FA, Ghosh R, Suen KM, Stagg LJ, Kirkpatrick J, Arold ST, Ahmed Z, Ladbury JE. Inhibition of basal FGF receptor signaling by dimeric Grb2. Cell. 2012 Jun 22; 149(7):1514-24. PMID: 22726438.
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Stevens CN, Simeone AM, John S, Ahmed Z, Lucherini OM, Baldari CT, Ladbury JE. T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation. Biochem J. 2010 May 27; 428(3):429-37. PMID: 20388118.
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Ahmed Z, George R, Lin CC, Suen KM, Levitt JA, Suhling K, Ladbury JE. Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function. Cell Signal. 2010 Jan; 22(1):23-33. PMID: 19735729.
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Schüller AC, Ahmed Z, Levitt JA, Suen KM, Suhling K, Ladbury JE. Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2). Biochem J. 2008 Dec 01; 416(2):189-99. PMID: 18840094.
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Ahmed Z, Schüller AC, Suhling K, Tregidgo C, Ladbury JE. Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling. Biochem J. 2008 Jul 01; 413(1):37-49. PMID: 18373495.
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Schüller AC, Ahmed Z, Ladbury JE. Extracellular point mutations in FGFR2 result in elevated ERK1/2 activation and perturbation of neuronal differentiation. Biochem J. 2008 Feb 15; 410(1):205-11. PMID: 18039182.
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Ahmed Z, Beeton CA, Williams MA, Clements D, Baldari CT, Ladbury JE. Distinct spatial and temporal distribution of ZAP70 and Lck following stimulation of interferon and T-cell receptors. J Mol Biol. 2005 Nov 11; 353(5):1001-10. PMID: 16219325.
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Grb2 monomer-dimer equilibrium determines normal versus oncogenic function. Nature Communications. 6.
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Erratum. Nature Communications. 6.
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Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli. Nature Structural and Molecular Biology.
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Grb2 depletion under non-stimulated conditions inhibits PTEN, promotes Akt-induced tumor formation and contributes to poor prognosis in ovarian cancer. Oncogene.
This graph shows the total number of publications by year, by first, middle/unknown, or last author.
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| Year | Publications |
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| 2005 | 1 | | 2008 | 3 | | 2009 | 1 | | 2010 | 1 | | 2012 | 1 | | 2013 | 3 | | 2014 | 2 | | 2015 | 3 | | 2017 | 1 | | 2018 | 1 | | 2019 | 1 |
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