JAVIER MEDINA

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Neuroscience
AddressOne Baylor Plaza
Houston, TX 77030
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    R01MH093727     (MEDINA, JAVIER F)Jun 2, 2011 - Dec 31, 2021
    NIH
    Coding and processing of error signals in inferior olivary-cerebellar networks
    Role: Principal Investigator

    R21AA025572     (MEDINA, JAVIER F)Sep 1, 2016 - Aug 31, 2018
    NIH
    Targets of low dose alcohol during cerebellar-driven behavior in mice
    Role: Principal Investigator

    RF1MH114269     (MEDINA, JAVIER F)Jul 19, 2017 - Jul 18, 2021
    NIH
    The impact of cerebellar tDCS in local and downstream brain circuits: how much is neuralactivity modulated in the resting state and during sensorimotor processing?
    Role: Principal Investigator

    R13NS113629     (MEDINA, JAVIER F)Jul 1, 2019 - Jun 30, 2020
    NIH
    2019 Cerebellum Gordon Research Conference and Gordon Research Seminar
    Role: Principal Investigator

    R01NS112917     (LISBERGER, STEPHEN G)Aug 1, 2019 - Apr 30, 2024
    NIH
    Canonical computations for motor learning by the cerebellar cortex micro-circuit
    Role: Co-Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sedaghat-Nejad E, Fakharian MA, Pi J, Hage P, Kojima Y, Soetedjo R, Ohmae S, Medina JF, Shadmehr R. P-sort: an open-source software for cerebellar neurophysiology. J Neurophysiol. 2021 08 25. PMID: 34432996.
      Citations:    Fields:    
    2. Achilly NP, He LJ, Kim OA, Ohmae S, Wojaczynski GJ, Lin T, Sillitoe RV, Medina JF, Zoghbi HY. Deleting Mecp2 from the cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice. Elife. 2021 Jan 26; 10. PMID: 33494858.
      Citations:    Fields:    
    3. Kim OA, Ohmae S, Medina JF. A cerebello-olivary signal for negative prediction error is sufficient to cause extinction of associative motor learning. Nat Neurosci. 2020 12; 23(12):1550-1554. PMID: 33169031.
      Citations:    Fields:    Translation:AnimalsCells
    4. Najafi F, Medina JF. Bidirectional short-term plasticity during single-trial learning of cerebellar-driven eyelid movements in mice. Neurobiol Learn Mem. 2020 04; 170:107097. PMID: 31610225.
      Citations: 2     Fields:    Translation:Animals
    5. Medina JF. Teaching the cerebellum about reward. Nat Neurosci. 2019 06; 22(6):846-848. PMID: 31127257.
      Citations: 2     Fields:    Translation:Cells
    6. Heiney SA, Ohmae S, Kim OA, Medina JF. Single-Unit Extracellular Recording from the Cerebellum During Eyeblink Conditioning in Head-Fixed Mice. Neuromethods. 2018; 134:39-71. PMID: 31156292.
      Citations: 1     
    7. Ten Brinke MM, Heiney SA, Wang X, Proietti-Onori M, Boele HJ, Bakermans J, Medina JF, Gao Z, De Zeeuw CI. Dynamic modulation of activity in cerebellar nuclei neurons during pavlovian eyeblink conditioning in mice. Elife. 2017 12 15; 6. PMID: 29243588.
      Citations: 32     Fields:    Translation:AnimalsCells
    8. Giovannucci A, Badura A, Deverett B, Najafi F, Pereira TD, Gao Z, Ozden I, Kloth AD, Pnevmatikakis E, Paninski L, De Zeeuw CI, Medina JF, Wang SS. Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning. Nat Neurosci. 2017 May; 20(5):727-734. PMID: 28319608.
      Citations: 56     Fields:    Translation:AnimalsCells
    9. Yang Y, Yamada T, Hill KK, Hemberg M, Reddy NC, Cho HY, Guthrie AN, Oldenborg A, Heiney SA, Ohmae S, Medina JF, Holy TE, Bonni A. Chromatin remodeling inactivates activity genes and regulates neural coding. Science. 2016 Jul 15; 353(6296):300-305. PMID: 27418512.
      Citations: 36     Fields:    Translation:AnimalsCells
    10. Lee J, Joshua M, Medina JF, Lisberger SG. Signal, Noise, and Variation in Neural and Sensory-Motor Latency. Neuron. 2016 Apr 06; 90(1):165-76. PMID: 26971946.
      Citations: 11     Fields:    Translation:AnimalsCells
    11. Ohmae S, Medina JF. Climbing fibers encode a temporal-difference prediction error during cerebellar learning in mice. Nat Neurosci. 2015 Dec; 18(12):1798-803. PMID: 26551541.
      Citations: 56     Fields:    Translation:AnimalsCells
    12. Heiney SA, Wohl MP, Chettih SN, Ruffolo LI, Medina JF. Cerebellar-dependent expression of motor learning during eyeblink conditioning in head-fixed mice. J Neurosci. 2014 Nov 05; 34(45):14845-53. PMID: 25378152.
      Citations: 58     Fields:    Translation:Animals
    13. Najafi F, Giovannucci A, Wang SS, Medina JF. Coding of stimulus strength via analog calcium signals in Purkinje cell dendrites of awake mice. Elife. 2014 Sep 09; 3:e03663. PMID: 25205669.
      Citations: 25     Fields:    Translation:AnimalsCells
    14. Heiney SA, Kim J, Augustine GJ, Medina JF. Precise control of movement kinematics by optogenetic inhibition of Purkinje cell activity. J Neurosci. 2014 Feb 05; 34(6):2321-30. PMID: 24501371.
      Citations: 103     Fields:    Translation:AnimalsCells
    15. Joshua M, Medina JF, Lisberger SG. Diversity of neural responses in the brainstem during smooth pursuit eye movements constrains the circuit mechanisms of neural integration. J Neurosci. 2013 Apr 10; 33(15):6633-47. PMID: 23575860.
      Citations: 11     Fields:    Translation:AnimalsCells
    16. Li JX, Medina JF, Frank LM, Lisberger SG. Acquisition of neural learning in cerebellum and cerebral cortex for smooth pursuit eye movements. J Neurosci. 2011 Sep 07; 31(36):12716-26. PMID: 21900551.
      Citations: 5     Fields:    Translation:AnimalsCells
    17. Medina JF, Lisberger SG. Encoding and decoding of learned smooth-pursuit eye movements in the floccular complex of the monkey cerebellum. J Neurophysiol. 2009 Oct; 102(4):2039-54. PMID: 19625543.
      Citations: 36     Fields:    Translation:AnimalsCells
    18. Medina JF, Lisberger SG. Links from complex spikes to local plasticity and motor learning in the cerebellum of awake-behaving monkeys. Nat Neurosci. 2008 Oct; 11(10):1185-92. PMID: 18806784.
      Citations: 118     Fields:    Translation:AnimalsCells
    19. Carey MR, Medina JF, Lisberger SG. Instructive signals for motor learning from visual cortical area MT. Nat Neurosci. 2005 Jun; 8(6):813-9. PMID: 15908949.
      Citations: 20     Fields:    Translation:AnimalsCells
    20. Medina JF, Nores WL, Mauk MD. Inhibition of climbing fibres is a signal for the extinction of conditioned eyelid responses. Nature. 2002 Mar 21; 416(6878):330-3. PMID: 11907580.
      Citations: 91     Fields:    Translation:AnimalsCells
    21. Medina JF, Repa JC, Mauk MD, LeDoux JE. Parallels between cerebellum- and amygdala-dependent conditioning. Nat Rev Neurosci. 2002 Feb; 3(2):122-31. PMID: 11836520.
      Citations: 67     Fields:    Translation:HumansAnimalsCells
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