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Last Name


TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentSchool of Health Professions
DivisionAllied Health Sciences
Address1 Baylor Plaza
Houston TX 77030
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    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Roy S, Esmaeilniakooshkghazi A, Patnaik S, Wang Y, George SP, Ahrorov A, Hou JK, Herron AJ, Sesaki H, Khurana S. Villin-1 and Gelsolin Regulate Changes in Actin Dynamics That Affect Cell Survival Signaling Pathways and Intestinal Inflammation. Gastroenterology. 2018 04; 154(5):1405-1420.e2. PMID: 29274870.
      View in: PubMed
    2. Rao J, Ashraf S, Tan W, van der Ven AT, Gee HY, Braun DA, Fehér K, George SP, Esmaeilniakooshkghazi A, Choi WI, Jobst-Schwan T, Schneider R, Schmidt JM, Widmeier E, Warejko JK, Hermle T, Schapiro D, Lovric S, Shril S, Daga A, Nayir A, Shenoy M, Tse Y, Bald M, Helmchen U, Mir S, Berdeli A, Kari JA, El Desoky S, Soliman NA, Bagga A, Mane S, Jairajpuri MA, Lifton RP, Khurana S, Martins JC, Hildebrandt F. Advillin acts upstream of phospholipase C ?1 in steroid-resistant nephrotic syndrome. J Clin Invest. 2017 12 01; 127(12):4257-4269. PMID: 29058690.
      View in: PubMed
    3. Mikami M, Zhang Y, Danielsson J, Joell T, Yong HM, Townsend E, Khurana S, An SS, Emala CW. Impaired Relaxation of Airway Smooth Muscle in Mice Lacking the Actin-Binding Protein Gelsolin. Am J Respir Cell Mol Biol. 2017 05; 56(5):628-636. PMID: 28118027.
      View in: PubMed
    4. Wang Y, George SP, Roy S, Pham E, Esmaeilniakooshkghazi A, Khurana S. Both the anti- and pro-apoptotic functions of villin regulate cell turnover and intestinal homeostasis. Sci Rep. 2016 10 21; 6:35491. PMID: 27765954.
      View in: PubMed
    5. Patnaik S, George SP, Pham E, Roy S, Singh K, Mariadason JM, Khurana S. By moonlighting in the nucleus, villin regulates epithelial plasticity. Mol Biol Cell. 2016 Feb 01; 27(3):535-48. PMID: 26658611; PMCID: PMC4751603.
    6. Liu WM, Zhang F, Moshiach S, Zhou B, Huang C, Srinivasan K, Khurana S, Zheng Y, Lahti JM, Zhang XA. Tetraspanin CD82 inhibits protrusion and retraction in cell movement by attenuating the plasma membrane-dependent actin organization. PLoS One. 2012; 7(12):e51797. PMID: 23251627; PMCID: PMC3522597.
    7. George SP, Chen H, Conrad JC, Khurana S. Regulation of directional cell migration by membrane-induced actin bundling. J Cell Sci. 2013 Jan 01; 126(Pt 1):312-26. PMID: 23132923; PMCID: PMC3603521.
    8. Khurana S, George SP. The role of actin bundling proteins in the assembly of filopodia in epithelial cells. Cell Adh Migr. 2011 Sep-Oct; 5(5):409-20. PMID: 21975550; PMCID: PMC3218608.
    9. Tomar A, George SP, Mathew S, Khurana S. Differential effects of lysophosphatidic acid and phosphatidylinositol 4,5-bisphosphate on actin dynamics by direct association with the actin-binding protein villin. J Biol Chem. 2009 Dec 18; 284(51):35278-82. PMID: 19808673; PMCID: PMC2790956.
    10. Mathew S, George SP, Wang Y, Siddiqui MR, Srinivasan K, Tan L, Khurana S. Potential molecular mechanism for c-Src kinase-mediated regulation of intestinal cell migration. J Biol Chem. 2008 Aug 15; 283(33):22709-22. PMID: 18482983; PMCID: PMC2504885.
    11. Khurana S, George SP. Regulation of cell structure and function by actin-binding proteins: villin's perspective. FEBS Lett. 2008 Jun 18; 582(14):2128-39. PMID: 18307996; PMCID: PMC2680319.
    12. Wang Y, Srinivasan K, Siddiqui MR, George SP, Tomar A, Khurana S. A novel role for villin in intestinal epithelial cell survival and homeostasis. J Biol Chem. 2008 Apr 04; 283(14):9454-64. PMID: 18198174.
      View in: PubMed
    13. Khurana S, Tomar A, George SP, Wang Y, Siddiqui MR, Guo H, Tigyi G, Mathew S. Autotaxin and lysophosphatidic acid stimulate intestinal cell motility by redistribution of the actin modifying protein villin to the developing lamellipodia. Exp Cell Res. 2008 Feb 01; 314(3):530-42. PMID: 18054784; PMCID: PMC2680351.
    14. George SP, Wang Y, Mathew S, Srinivasan K, Khurana S. Dimerization and actin-bundling properties of villin and its role in the assembly of epithelial cell brush borders. J Biol Chem. 2007 Sep 07; 282(36):26528-41. PMID: 17606613.
      View in: PubMed
    15. Wang Y, Tomar A, George SP, Khurana S. Obligatory role for phospholipase C-gamma(1) in villin-induced epithelial cell migration. Am J Physiol Cell Physiol. 2007 May; 292(5):C1775-86. PMID: 17229814.
      View in: PubMed
    16. Tomar A, George S, Kansal P, Wang Y, Khurana S. Interaction of phospholipase C-gamma1 with villin regulates epithelial cell migration. J Biol Chem. 2006 Oct 20; 281(42):31972-86. PMID: 16921170.
      View in: PubMed
    17. Tomar A, Wang Y, Kumar N, George S, Ceacareanu B, Hassid A, Chapman KE, Aryal AM, Waters CM, Khurana S. Regulation of cell motility by tyrosine phosphorylated villin. Mol Biol Cell. 2004 Nov; 15(11):4807-17. PMID: 15342783.
      View in: PubMed
    18. Kumar N, Tomar A, Parrill AL, Khurana S. Functional dissection and molecular characterization of calcium-sensitive actin-capping and actin-depolymerizing sites in villin. J Biol Chem. 2004 Oct 22; 279(43):45036-46. PMID: 15272027.
      View in: PubMed
    19. Kumar N, Khurana S. Identification of a functional switch for actin severing by cytoskeletal proteins. J Biol Chem. 2004 Jun 11; 279(24):24915-8. PMID: 15084600.
      View in: PubMed
    20. Kumar N, Zhao P, Tomar A, Galea CA, Khurana S. Association of villin with phosphatidylinositol 4,5-bisphosphate regulates the actin cytoskeleton. J Biol Chem. 2004 Jan 23; 279(4):3096-110. PMID: 14594952.
      View in: PubMed
    21. Zhai L, Kumar N, Panebra A, Zhao P, Parrill AL, Khurana S. Regulation of actin dynamics by tyrosine phosphorylation: identification of tyrosine phosphorylation sites within the actin-severing domain of villin. Biochemistry. 2002 Oct 01; 41(39):11750-60. PMID: 12269817.
      View in: PubMed
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