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BORIS BLECHACZ

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGastroenterology Hepatology & Nutrition
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Miller ED, Abu-Sbeih H, Styskel B, Nogueras Gonzalez GM, Blechacz B, Naing A, Chalasani N. Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors. Am J Gastroenterol. 2020 02; 115(2):251-261. PMID: 31789632.
      View in: PubMed
    2. Raju G, Lum P, Ross W, Thirumurthi S, Miller E, Lynch P, Lee J, Bhutani MS, Shafi MA, Weston B, Blechacz B, Chang GJ, Hagan K, Rashid A, Davila M, Stroehlein J. Quality of endoscopy reporting at index colonoscopy significantly impacts outcome of subsequent EMR in patients with > 20?mm colon polyps. Endosc Int Open. 2019 Mar; 7(3):E361-E366. PMID: 30834295.
      View in: PubMed
    3. Torres HA, Economides MP, Angelidakis G, Hosry J, Kyvernitakis A, Mahale P, Jiang Y, Miller E, Blechacz B, Naing A, Samaniego F, Kaseb A, Raad II, Granwehr BP. Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study. Am J Gastroenterol. 2019 02; 114(2):250-257. PMID: 30410039.
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    4. Wang Y, Abu-Sbeih H, Mao E, Ali N, Qiao W, Trinh VA, Zobniw C, Johnson DH, Samdani R, Lum P, Shuttlesworth G, Blechacz B, Bresalier R, Miller E, Thirumurthi S, Richards D, Raju G, Stroehlein J, Diab A. Endoscopic and Histologic Features of Immune Checkpoint Inhibitor-Related Colitis. Inflamm Bowel Dis. 2018 07 12; 24(8):1695-1705. PMID: 29718308.
      View in: PubMed
    5. Zhang P, Rojas A, Blechacz B. Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation. J Vis Exp. 2017 06 27; (124). PMID: 28715365.
      View in: PubMed
    6. Hust MA, Blechacz BRA, Bonilla DL, Daver N, Rojas-Hernandez CM. Adult cancer-related hemophagocytic lymphohistiocytosis - a challenging diagnosis: a case report. J Med Case Rep. 2017 Jun 27; 11(1):172. PMID: 28651636.
      View in: PubMed
    7. Daver N, McClain K, Allen CE, Parikh SA, Otrock Z, Rojas-Hernandez C, Blechacz B, Wang S, Minkov M, Jordan MB, La Rosée P, Kantarjian HM. A consensus review on malignancy-associated hemophagocytic lymphohistiocytosis in adults. Cancer. 2017 Sep 01; 123(17):3229-3240. PMID: 28621800.
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    8. Blechacz B. Cholangiocarcinoma: Current Knowledge and New Developments. Gut Liver. 2017 Jan 15; 11(1):13-26. PMID: 27928095.
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    9. Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L. Loss of the transforming growth factor-ß effector ß2-Spectrin promotes genomic instability. Hepatology. 2017 02; 65(2):678-693. PMID: 28114741.
      View in: PubMed
    10. Torres HA, Roach LR, Mahale P, Economides MP, Blechacz B, Miller E, Borchardt R, Rashid A, Oo TH, Shukla B, Farida M, Ericsson CD, Granwehr BP, Raad II. Transdisciplinary Approach to Managing Hepatitis C Virus Infection in Patients at a Tertiary Care Cancer Center. J Natl Compr Canc Netw. 2016 09; 14(9):1185-8. PMID: 27587628.
      View in: PubMed
    11. Rojas A, Zhang P, Wang Y, Foo WC, Muñoz NM, Xiao L, Wang J, Gores GJ, Hung MC, Blechacz B. A Positive TGF-ß/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer. Neoplasia. 2016 06; 18(6):371-86. PMID: 27292026.
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    12. Raju GS, Lum PJ, Slack RS, Thirumurthi S, Lynch PM, Miller E, Weston BR, Davila ML, Bhutani MS, Shafi MA, Bresalier RS, Dekovich AA, Lee JH, Guha S, Pande M, Blechacz B, Rashid A, Routbort M, Shuttlesworth G, Mishra L, Stroehlein JR, Ross WA. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointest Endosc. 2015 Sep; 82(3):512-9. PMID: 25910665.
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    13. Blechacz B, Mishra L. Biopsy for liver cancer: How to balance research needs with evidence-based clinical practice. Hepatology. 2015 Nov; 62(5):1645. PMID: 25678381.
      View in: PubMed
    14. Ghouri YA, Mian I, Blechacz B. Cancer review: Cholangiocarcinoma. J Carcinog. 2015; 14:1. PMID: 25788866.
      View in: PubMed
    15. Zhu H, Berkova Z, Mathur R, Sehgal L, Khashab T, Tao RH, Ao X, Feng L, Sabichi AL, Blechacz B, Rashid A, Samaniego F. HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer. Mol Cancer Res. 2015 May; 13(5):809-18. PMID: 25678597.
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    16. Kyvernitakis A, Taremi M, Blechacz B, Hwang J, Jiang Y, Mahale P, Torres HA. Impact of hepatitis E virus seropositivity on chronic liver disease in cancer patients with hepatitis C virus infection. Hepatol Res. 2015 Nov; 45(11):1146-51. PMID: 25488194.
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    17. Torres HA, Mahale P, Blechacz B, Miller E, Kaseb A, Herlong HF, Fowler N, Jiang Y, Raad II, Kontoyiannis DP. Effect of hepatitis C virus infection in patients with cancer: addressing a neglected population. J Natl Compr Canc Netw. 2015 Jan; 13(1):41-50. PMID: 25583768.
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    18. Blechacz B, Mishra L. Hepatocellular carcinoma biology. Recent Results Cancer Res. 2013; 190:1-20. PMID: 22941010.
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    19. Andersen JB, Spee B, Blechacz BR, Avital I, Komuta M, Barbour A, Conner EA, Gillen MC, Roskams T, Roberts LR, Factor VM, Thorgeirsson SS. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors. Gastroenterology. 2012 Apr; 142(4):1021-1031.e15. PMID: 22178589.
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    20. Blechacz B, Komuta M, Roskams T, Gores GJ. Clinical diagnosis and staging of cholangiocarcinoma. Nat Rev Gastroenterol Hepatol. 2011 Aug 02; 8(9):512-22. PMID: 21808282.
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    21. Thabut D, Routray C, Lomberk G, Shergill U, Glaser K, Huebert R, Patel L, Masyuk T, Blechacz B, Vercnocke A, Ritman E, Ehman R, Urrutia R, Shah V. Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. Hepatology. 2011 Aug; 54(2):573-85. PMID: 21567441.
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    22. Blechacz B, Gores GJ. Positron emission tomography scan for a hepatic mass. Hepatology. 2010 Dec; 52(6):2186-91. PMID: 20967825.
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    23. Fingas CD, Blechacz BR, Smoot RL, Guicciardi ME, Mott J, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells. Hepatology. 2010 Aug; 52(2):550-61. PMID: 20683954.
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    24. Smoot RL, Blechacz BR, Werneburg NW, Bronk SF, Sinicrope FA, Sirica AE, Gores GJ. A Bax-mediated mechanism for obatoclax-induced apoptosis of cholangiocarcinoma cells. Cancer Res. 2010 Mar 01; 70(5):1960-9. PMID: 20160031.
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    25. Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. Hepatology. 2009 Dec; 50(6):1861-70. PMID: 19821497.
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    26. Blechacz BR, Sanchez W, Gores GJ. A conceptual proposal for staging ductal cholangiocarcinoma. Curr Opin Gastroenterol. 2009 May; 25(3):238-9. PMID: 19387257.
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    27. Briel M, Ferreira-Gonzalez I, You JJ, Karanicolas PJ, Akl EA, Wu P, Blechacz B, Bassler D, Wei X, Sharman A, Whitt I, Alves da Silva S, Khalid Z, Nordmann AJ, Zhou Q, Walter SD, Vale N, Bhatnagar N, O'Regan C, Mills EJ, Bucher HC, Montori VM, Guyatt GH. Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. BMJ. 2009 Feb 16; 338:b92. PMID: 19221140.
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    28. Blechacz B, Gores GJ. Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology. 2008 Jul; 48(1):308-21. PMID: 18536057.
      View in: PubMed
    29. Blechacz B, Gajic O. Images in clinical medicine. Severe kyphosis. N Engl J Med. 2008 Jun 12; 358(24):e28. PMID: 18550872.
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    30. Blechacz B, Russell SJ. Measles virus as an oncolytic vector platform. Curr Gene Ther. 2008 Jun; 8(3):162-75. PMID: 18537591.
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    31. Blechacz B, Gores GJ. Tumor-specific marker genes for intrahepatic cholangiocarcinoma: utility and mechanistic insight. J Hepatol. 2008 Aug; 49(2):160-2. PMID: 18538440.
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    32. Blechacz BR, Gores GJ. Cholangiocarcinoma. Clin Liver Dis. 2008 Feb; 12(1):131-50, ix. PMID: 18242501.
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    33. Iankov ID, Blechacz B, Liu C, Schmeckpeper JD, Tarara JE, Federspiel MJ, Caplice N, Russell SJ. Infected cell carriers: a new strategy for systemic delivery of oncolytic measles viruses in cancer virotherapy. Mol Ther. 2007 Jan; 15(1):114-22. PMID: 17164782.
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    34. Blechacz B, Splinter PL, Greiner S, Myers R, Peng KW, Federspiel MJ, Russell SJ, LaRusso NF. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology. 2006 Dec; 44(6):1465-77. PMID: 17133484.
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    35. Blechacz B, Russell SJ. Parvovirus vectors: use and optimisation in cancer gene therapy. Expert Rev Mol Med. 2004 Jul 23; 6(16):1-24. PMID: 15387896.
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    36. Blechacz B, Stremmel W. [NASH -- nonalcoholic steatohepatitis]. Z Gastroenterol. 2003 Jan; 41(1):77-90. PMID: 12541180.
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    37. Stremmel W, Blechacz B, Herrmann T, Rost D, Mueller S. [Therapy of alcoholic and non-alcoholic fatty liver]. Internist (Berl). 2001 Dec; 42(12):1641-2, 1645-50. PMID: 11793603.
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    38. Moehler M, Blechacz B, Weiskopf N, Zeidler M, Stremmel W, Rommelaere J, Galle PR, Cornelis JJ. Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors. Cancer Gene Ther. 2001 Mar; 8(3):158-67. PMID: 11332986.
      View in: PubMed
    39. Biopsy for liver cancer. Hepatology.
    40. Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability. Hepatology. 65:678-693.
    41. Severe kyphosis. New England Journal of Medicine. 358.
    42. HuR suppresses fas expression and correlates with patient outcome in liver cancer. Molecular Cancer Research. 13:809-818.
    43. Primary Hepatic Cancer. 161-181.
    44. Transdisciplinary approach to managing hepatitis c virus infection in patients at a tertiary care cancer center. JNCCN Journal of the National Comprehensive Cancer Network. 14:1185-1188.
    45. Severe hepatitis C reactivation as an early complication of hematopoietic cell transplantation. Bone Marrow Transplantation.
    46. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointestinal Endoscopy.
    47. Impact of hepatitis E virus seropositivity on chronic liver disease in cancer patients with hepatitis C virus infection. Hepatology Research. 45:1146-1151.
    48. Atypical case presentation of Zieve's syndrome. Practical Gastroenterology. 37:47-49.
    49. Cancer review. Journal of Carcinogenesis. 14.
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