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BORIS BLECHACZ

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGastroenterology Hepatology & Nutrition
Address1400 Pressler St
Houston TX 77030-4008
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Yakovchenko V, Merante M, Rabiee A, McCurdy H, Rogal SS, Taddei TH, Monto A, Patton H, Spoutz P, Chia L, Yudkevich J, Aytaman A, John BV, Blechacz B, Cai CX, Gilles H, Shah AS, Puri P, Jou J, Mazhar K, Dominitz JA, Anwar J, Morgan TR, Ioannou GN. Hepatocellular Carcinoma Diagnosis and Management in 2021: A National Veterans Affairs Quality Improvement Project. Clin Gastroenterol Hepatol. 2024 02; 22(2):324-338. PMID: 37460005; PMCID: PMC10788380.
      Citations:    Fields:    Translation:Humans
    2. Miller ED, Abu-Sbeih H, Styskel B, Nogueras Gonzalez GM, Blechacz B, Naing A, Chalasani N. Clinical Characteristics and Adverse Impact of Hepatotoxicity due to Immune Checkpoint Inhibitors. Am J Gastroenterol. 2020 02; 115(2):251-261. PMID: 31789632.
      Citations: 9     Fields:    Translation:Humans
    3. Raju G, Lum P, Ross W, Thirumurthi S, Miller E, Lynch P, Lee J, Bhutani MS, Shafi MA, Weston B, Blechacz B, Chang GJ, Hagan K, Rashid A, Davila M, Stroehlein J. Quality of endoscopy reporting at index colonoscopy significantly impacts outcome of subsequent EMR in patients with > 20?mm colon polyps. Endosc Int Open. 2019 Mar; 7(3):E361-E366. PMID: 30834295; PMCID: PMC6395098.
      Citations: 2     
    4. Torres HA, Economides MP, Angelidakis G, Hosry J, Kyvernitakis A, Mahale P, Jiang Y, Miller E, Blechacz B, Naing A, Samaniego F, Kaseb A, Raad II, Granwehr BP. Sofosbuvir-Based Therapy in Hepatitis C Virus-Infected Cancer Patients: A Prospective Observational Study. Am J Gastroenterol. 2019 02; 114(2):250-257. PMID: 30410039.
      Citations: 5     Fields:    Translation:Humans
    5. Wang Y, Abu-Sbeih H, Mao E, Ali N, Qiao W, Trinh VA, Zobniw C, Johnson DH, Samdani R, Lum P, Shuttlesworth G, Blechacz B, Bresalier R, Miller E, Thirumurthi S, Richards D, Raju G, Stroehlein J, Diab A. Endoscopic and Histologic Features of Immune Checkpoint Inhibitor-Related Colitis. Inflamm Bowel Dis. 2018 07 12; 24(8):1695-1705. PMID: 29718308.
      Citations: 61     Fields:    Translation:Humans
    6. Hust MA, Blechacz BRA, Bonilla DL, Daver N, Rojas-Hernandez CM. Adult cancer-related hemophagocytic lymphohistiocytosis - a challenging diagnosis: a case report. J Med Case Rep. 2017 Jun 27; 11(1):172. PMID: 28651636; PMCID: PMC5485603.
      Citations: 1     Fields:    Translation:HumansCells
    7. Zhang P, Rojas A, Blechacz B. Analysis of the c-KIT Ligand Promoter Using Chromatin Immunoprecipitation. J Vis Exp. 2017 06 27; (124). PMID: 28715365; PMCID: PMC5608525.
      Citations:    Fields:    Translation:HumansCells
    8. Daver N, McClain K, Allen CE, Parikh SA, Otrock Z, Rojas-Hernandez C, Blechacz B, Wang S, Minkov M, Jordan MB, Kantarjian HM, La Ros?e P. A consensus review on malignancy-associated hemophagocytic lymphohistiocytosis in adults. Cancer. 2017 Sep 01; 123(17):3229-3240. PMID: 28621800; PMCID: PMC5568927.
      Citations: 58     Fields:    Translation:Humans
    9. Blechacz B. Cholangiocarcinoma: Current Knowledge and New Developments. Gut Liver. 2017 Jan 15; 11(1):13-26. PMID: 27928095; PMCID: PMC5221857.
      Citations: 146     Fields:    Translation:Humans
    10. Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, Stroehlein JR, Chen J, Kim SS, Levin H, Machida K, Tsukamoto H, Michaely P, Tzatsos A, Mishra B, Amdur R, Mishra L. Loss of the transforming growth factor-? effector ?2-Spectrin promotes genomic instability. Hepatology. 2017 02; 65(2):678-693. PMID: 28114741; PMCID: PMC5432427.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    11. Torres HA, Roach LR, Mahale P, Economides MP, Blechacz B, Miller E, Borchardt R, Rashid A, Oo TH, Shukla B, Farida M, Ericsson CD, Granwehr BP, Raad II. Transdisciplinary Approach to Managing Hepatitis C Virus Infection in Patients at a Tertiary Care Cancer Center. J Natl Compr Canc Netw. 2016 09; 14(9):1185-8. PMID: 27587628.
      Citations: 1     Fields:    Translation:HumansCells
    12. Oliver NT, Nieto YL, Blechacz B, Anderlini P, Ariza-Heredia E, Torres HA. Severe hepatitis C reactivation as an early complication of hematopoietic cell transplantation. Bone Marrow Transplant. 2017 01; 52(1):138-140. PMID: 27427916.
      Citations: 4     Fields:    Translation:Humans
    13. Rojas A, Zhang P, Wang Y, Foo WC, Xiao L, Wang J, Gores GJ, Hung MC, Blechacz B, Mu?oz NM. A Positive TGF-?/c-KIT Feedback Loop Drives Tumor Progression in Advanced Primary Liver Cancer. Neoplasia. 2016 06; 18(6):371-86. PMID: 27292026; PMCID: PMC4909706.
      Citations: 16     Fields:    Translation:HumansCells
    14. Raju GS, Lum PJ, Slack RS, Thirumurthi S, Lynch PM, Miller E, Weston BR, Davila ML, Bhutani MS, Shafi MA, Bresalier RS, Dekovich AA, Lee JH, Guha S, Pande M, Blechacz B, Rashid A, Routbort M, Shuttlesworth G, Mishra L, Stroehlein JR, Ross WA. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointest Endosc. 2015 Sep; 82(3):512-9. PMID: 25910665; PMCID: PMC4540652.
      Citations: 34     Fields:    Translation:Humans
    15. Blechacz B, Mishra L. Biopsy for liver cancer: How to balance research needs with evidence-based clinical practice. Hepatology. 2015 Nov; 62(5):1645. PMID: 25678381.
      Citations: 3     Fields:    Translation:Humans
    16. Ghouri YA, Mian I, Blechacz B. Cancer review: Cholangiocarcinoma. J Carcinog. 2015; 14:1. PMID: 25788866; PMCID: PMC4360553.
      Citations: 61     
    17. Zhu H, Berkova Z, Mathur R, Sehgal L, Khashab T, Tao RH, Ao X, Feng L, Sabichi AL, Blechacz B, Rashid A, Samaniego F. HuR Suppresses Fas Expression and Correlates with Patient Outcome in Liver Cancer. Mol Cancer Res. 2015 May; 13(5):809-18. PMID: 25678597.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    18. Kyvernitakis A, Taremi M, Blechacz B, Hwang J, Jiang Y, Mahale P, Torres HA. Impact of hepatitis E virus seropositivity on chronic liver disease in cancer patients with hepatitis C virus infection. Hepatol Res. 2015 Nov; 45(11):1146-51. PMID: 25488194.
      Citations: 5     
    19. Torres HA, Mahale P, Blechacz B, Miller E, Kaseb A, Herlong HF, Fowler N, Jiang Y, Raad II, Kontoyiannis DP. Effect of hepatitis C virus infection in patients with cancer: addressing a neglected population. J Natl Compr Canc Netw. 2015 Jan; 13(1):41-50. PMID: 25583768.
      Citations: 11     Fields:    Translation:HumansCells
    20. Blechacz B, Mishra L. Hepatocellular carcinoma biology. Recent Results Cancer Res. 2013; 190:1-20. PMID: 22941010.
      Citations: 26     Fields:    Translation:HumansCells
    21. Andersen JB, Spee B, Blechacz BR, Avital I, Komuta M, Barbour A, Conner EA, Gillen MC, Roskams T, Roberts LR, Factor VM, Thorgeirsson SS. Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors. Gastroenterology. 2012 Apr; 142(4):1021-1031.e15. PMID: 22178589; PMCID: PMC3413201.
      Citations: 200     Fields:    Translation:HumansCells
    22. Blechacz B, Komuta M, Roskams T, Gores GJ. Clinical diagnosis and staging of cholangiocarcinoma. Nat Rev Gastroenterol Hepatol. 2011 Aug 02; 8(9):512-22. PMID: 21808282; PMCID: PMC3331791.
      Citations: 229     Fields:    Translation:Humans
    23. Thabut D, Routray C, Lomberk G, Shergill U, Glaser K, Huebert R, Patel L, Masyuk T, Blechacz B, Vercnocke A, Ritman E, Ehman R, Urrutia R, Shah V. Complementary vascular and matrix regulatory pathways underlie the beneficial mechanism of action of sorafenib in liver fibrosis. Hepatology. 2011 Aug; 54(2):573-85. PMID: 21567441; PMCID: PMC3145033.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    24. Blechacz B, Gores GJ. Positron emission tomography scan for a hepatic mass. Hepatology. 2010 Dec; 52(6):2186-91. PMID: 20967825; PMCID: PMC3059121.
      Citations: 5     Fields:    Translation:Humans
    25. Fingas CD, Blechacz BR, Smoot RL, Guicciardi ME, Mott J, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. A smac mimetic reduces TNF related apoptosis inducing ligand (TRAIL)-induced invasion and metastasis of cholangiocarcinoma cells. Hepatology. 2010 Aug; 52(2):550-61. PMID: 20683954; PMCID: PMC2957364.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    26. Smoot RL, Blechacz BR, Werneburg NW, Bronk SF, Sinicrope FA, Sirica AE, Gores GJ. A Bax-mediated mechanism for obatoclax-induced apoptosis of cholangiocarcinoma cells. Cancer Res. 2010 Mar 01; 70(5):1960-9. PMID: 20160031; PMCID: PMC2831099.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    27. Blechacz BR, Smoot RL, Bronk SF, Werneburg NW, Sirica AE, Gores GJ. Sorafenib inhibits signal transducer and activator of transcription-3 signaling in cholangiocarcinoma cells by activating the phosphatase shatterproof 2. Hepatology. 2009 Dec; 50(6):1861-70. PMID: 19821497; PMCID: PMC2891152.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    28. Blechacz BR, Sanchez W, Gores GJ. A conceptual proposal for staging ductal cholangiocarcinoma. Curr Opin Gastroenterol. 2009 May; 25(3):238-9. PMID: 19387257; PMCID: PMC2898128.
      Citations: 12     Fields:    Translation:Humans
    29. Briel M, Ferreira-Gonzalez I, You JJ, Karanicolas PJ, Akl EA, Wu P, Blechacz B, Bassler D, Wei X, Sharman A, Whitt I, Alves da Silva S, Khalid Z, Nordmann AJ, Zhou Q, Walter SD, Vale N, Bhatnagar N, O'Regan C, Mills EJ, Bucher HC, Montori VM, Guyatt GH. Association between change in high density lipoprotein cholesterol and cardiovascular disease morbidity and mortality: systematic review and meta-regression analysis. BMJ. 2009 Feb 16; 338:b92. PMID: 19221140; PMCID: PMC2645847.
      Citations: 142     Fields:    Translation:Humans
    30. Blechacz B, Gores GJ. Cholangiocarcinoma: advances in pathogenesis, diagnosis, and treatment. Hepatology. 2008 Jul; 48(1):308-21. PMID: 18536057; PMCID: PMC2547491.
      Citations: 275     Fields:    Translation:HumansAnimals
    31. Blechacz B, Gajic O. Images in clinical medicine. Severe kyphosis. N Engl J Med. 2008 Jun 12; 358(24):e28. PMID: 18550872.
      Citations: 3     Fields:    Translation:Humans
    32. Blechacz B, Russell SJ. Measles virus as an oncolytic vector platform. Curr Gene Ther. 2008 Jun; 8(3):162-75. PMID: 18537591.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    33. Blechacz B, Gores GJ. Tumor-specific marker genes for intrahepatic cholangiocarcinoma: utility and mechanistic insight. J Hepatol. 2008 Aug; 49(2):160-2. PMID: 18538440; PMCID: PMC2885696.
      Citations: 7     Fields:    Translation:Humans
    34. Blechacz BR, Gores GJ. Cholangiocarcinoma. Clin Liver Dis. 2008 Feb; 12(1):131-50, ix. PMID: 18242501.
      Citations: 106     Fields:    Translation:Humans
    35. Iankov ID, Blechacz B, Liu C, Schmeckpeper JD, Tarara JE, Federspiel MJ, Caplice N, Russell SJ. Infected cell carriers: a new strategy for systemic delivery of oncolytic measles viruses in cancer virotherapy. Mol Ther. 2007 Jan; 15(1):114-22. PMID: 17164782.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    36. Blechacz B, Splinter PL, Greiner S, Myers R, Peng KW, Federspiel MJ, Russell SJ, LaRusso NF. Engineered measles virus as a novel oncolytic viral therapy system for hepatocellular carcinoma. Hepatology. 2006 Dec; 44(6):1465-77. PMID: 17133484.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    37. Blechacz B, Russell SJ. Parvovirus vectors: use and optimisation in cancer gene therapy. Expert Rev Mol Med. 2004 Jul 23; 6(16):1-24. PMID: 15387896.
      Citations: 5     Fields:    Translation:HumansCells
    38. Blechacz B, Stremmel W. [NASH -- nonalcoholic steatohepatitis]. Z Gastroenterol. 2003 Jan; 41(1):77-90. PMID: 12541180.
      Citations:    Fields:    Translation:HumansCells
    39. Stremmel W, Blechacz B, Herrmann T, Rost D, Mueller S. [Therapy of alcoholic and non-alcoholic fatty liver]. Internist (Berl). 2001 Dec; 42(12):1641-2, 1645-50. PMID: 11793603.
      Citations:    Fields:    Translation:Humans
    40. Moehler M, Blechacz B, Weiskopf N, Zeidler M, Stremmel W, Rommelaere J, Galle PR, Cornelis JJ. Effective infection, apoptotic cell killing and gene transfer of human hepatoma cells but not primary hepatocytes by parvovirus H1 and derived vectors. Cancer Gene Ther. 2001 Mar; 8(3):158-67. PMID: 11332986.
      Citations: 28     Fields:    Translation:HumansCells
    41. Biopsy for liver cancer. Hepatology.
    42. Loss of the transforming growth factor-β effector β2-Spectrin promotes genomic instability. Hepatology. 65:678-693.
    43. Severe kyphosis. New England Journal of Medicine. 358.
    44. HuR suppresses fas expression and correlates with patient outcome in liver cancer. Molecular Cancer Research. 13:809-818.
    45. Primary Hepatic Cancer. 161-181.
    46. Transdisciplinary approach to managing hepatitis c virus infection in patients at a tertiary care cancer center. JNCCN Journal of the National Comprehensive Cancer Network. 14:1185-1188.
    47. Severe hepatitis C reactivation as an early complication of hematopoietic cell transplantation. Bone Marrow Transplantation.
    48. Natural language processing as an alternative to manual reporting of colonoscopy quality metrics. Gastrointestinal Endoscopy.
    49. Impact of hepatitis E virus seropositivity on chronic liver disease in cancer patients with hepatitis C virus infection. Hepatology Research. 45:1146-1151.
    50. Atypical case presentation of Zieve's syndrome. Practical Gastroenterology. 37:47-49.
    51. Cancer review. Journal of Carcinogenesis. 14.
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