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SHILPA S. DHAR

TitleInstructor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Liu Y, Qin S, Chen TY, Lei M, Dhar SS, Ho JC, Dong A, Loppnau P, Li Y, Lee MG, Min J. Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4. Nat Commun. 2019 01 03; 10(1):36. PMID: 30604749.
      View in: PubMed
    2. Dhar SS, Zhao D, Lin T, Gu B, Pal K, Wu SJ, Alam H, Lv J, Yun K, Gopalakrishnan V, Flores ER, Northcott PA, Rajaram V, Li W, Shilatifard A, Sillitoe RV, Chen K, Lee MG. MLL4 Is Required to Maintain Broad H3K4me3 Peaks and Super-Enhancers at Tumor Suppressor Genes. Mol Cell. 2018 06 07; 70(5):825-841.e6. PMID: 29861161.
      View in: PubMed
    3. Alam H, Li N, Dhar SS, Wu SJ, Lv J, Chen K, Flores ER, Baseler L, Lee MG. HP1? Promotes Lung Adenocarcinoma by Downregulating the Transcription-Repressive Regulators NCOR2 and ZBTB7A. Cancer Res. 2018 07 15; 78(14):3834-3848. PMID: 29764865.
      View in: PubMed
    4. Chen TY, Lee SH, Dhar SS, Lee MG. Protein arginine methyltransferase 7-mediated microRNA-221 repression maintains Oct4, Nanog, and Sox2 levels in mouse embryonic stem cells. J Biol Chem. 2018 03 16; 293(11):3925-3936. PMID: 29378844.
      View in: PubMed
    5. Lee SH, Chen TY, Dhar SS, Gu B, Chen K, Kim YZ, Li W, Lee MG. A feedback loop comprising PRMT7 and miR-24-2 interplays with Oct4, Nanog, Klf4 and c-Myc to regulate stemness. Nucleic Acids Res. 2016 12 15; 44(22):10603-10618. PMID: 27625395.
      View in: PubMed
    6. Li N, Li Y, Lv J, Zheng X, Wen H, Shen H, Zhu G, Chen TY, Dhar SS, Kan PY, Wang Z, Shiekhattar R, Shi X, Lan F, Chen K, Li W, Li H, Lee MG. ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Mol Cell. 2016 08 04; 63(3):470-84. PMID: 27477906.
      View in: PubMed
    7. Dhar SS, Lee SH, Chen K, Zhu G, Oh W, Allton K, Gafni O, Kim YZ, Tomoiga AS, Barton MC, Hanna JH, Wang Z, Li W, Lee MG. An essential role for UTX in resolution and activation of bivalent promoters. Nucleic Acids Res. 2016 05 05; 44(8):3659-74. PMID: 26762983.
      View in: PubMed
    8. Li N, Dhar SS, Chen TY, Kan PY, Wei Y, Kim JH, Chan CH, Lin HK, Hung MC, Lee MG. JARID1D Is a Suppressor and Prognostic Marker of Prostate Cancer Invasion and Metastasis. Cancer Res. 2016 Feb 15; 76(4):831-43. PMID: 26747897.
      View in: PubMed
    9. Kim JH, Sharma A, Dhar SS, Lee SH, Gu B, Chan CH, Lin HK, Lee MG. UTX and MLL4 coordinately regulate transcriptional programs for cell proliferation and invasiveness in breast cancer cells. Cancer Res. 2014 Mar 15; 74(6):1705-17. PMID: 24491801.
      View in: PubMed
    10. Dhar SS, Alam H, Li N, Wagner KW, Chung J, Ahn YW, Lee MG. Transcriptional repression of histone deacetylase 3 by the histone demethylase KDM2A is coupled to tumorigenicity of lung cancer cells. J Biol Chem. 2014 Mar 14; 289(11):7483-96. PMID: 24482232.
      View in: PubMed
    11. Wagner KW, Alam H, Dhar SS, Giri U, Li N, Wei Y, Giri D, Cascone T, Kim JH, Ye Y, Multani AS, Chan CH, Erez B, Saigal B, Chung J, Lin HK, Wu X, Hung MC, Heymach JV, Lee MG. KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling. J Clin Invest. 2013 Dec; 123(12):5231-46. PMID: 24200691.
      View in: PubMed
    12. Johar K, Priya A, Dhar S, Liu Q, Wong-Riley MT. Neuron-specific specificity protein 4 bigenomically regulates the transcription of all mitochondria- and nucleus-encoded cytochrome c oxidase subunit genes in neurons. J Neurochem. 2013 Nov; 127(4):496-508. PMID: 24032355.
      View in: PubMed
    13. Dhar SS, Johar K, Wong-Riley MT. Bigenomic transcriptional regulation of all thirteen cytochrome c oxidase subunit genes by specificity protein 1. Open Biol. 2013 Mar 20; 3(3):120176. PMID: 23516108.
      View in: PubMed
    14. Dhar SS, Lee SH, Kan PY, Voigt P, Ma L, Shi X, Reinberg D, Lee MG. Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4. Genes Dev. 2012 Dec 15; 26(24):2749-62. PMID: 23249737.
      View in: PubMed
    15. Dhar SS, Wong-Riley MT. The kinesin superfamily protein KIF17 is regulated by the same transcription factor (NRF-1) as its cargo NR2B in neurons. Biochim Biophys Acta. 2011 Mar; 1813(3):403-11. PMID: 21172391.
      View in: PubMed
    16. Dhar SS, Wong-Riley MT. Chromosome conformation capture of transcriptional interactions between cytochrome c oxidase genes and genes of glutamatergic synaptic transmission in neurons. J Neurochem. 2010 Nov; 115(3):676-83. PMID: 21064266.
      View in: PubMed
    17. Liang HL, Dhar SS, Wong-Riley MT. p38 mitogen-activated protein kinase and calcium channels mediate signaling in depolarization-induced activation of peroxisome proliferator-activated receptor gamma coactivator-1alpha in neurons. J Neurosci Res. 2010 Feb 15; 88(3):640-9. PMID: 19774670.
      View in: PubMed
    18. Dhar SS, Liang HL, Wong-Riley MT. Transcriptional coupling of synaptic transmission and energy metabolism: role of nuclear respiratory factor 1 in co-regulating neuronal nitric oxide synthase and cytochrome c oxidase genes in neurons. Biochim Biophys Acta. 2009 Oct; 1793(10):1604-13. PMID: 19615412.
      View in: PubMed
    19. Dhar SS, Ongwijitwat S, Wong-Riley MT. Chromosome conformation capture of all 13 genomic Loci in the transcriptional regulation of the multisubunit bigenomic cytochrome C oxidase in neurons. J Biol Chem. 2009 Jul 10; 284(28):18644-50. PMID: 19439416.
      View in: PubMed
    20. Dhar SS, Liang HL, Wong-Riley MT. Nuclear respiratory factor 1 co-regulates AMPA glutamate receptor subunit 2 and cytochrome c oxidase: tight coupling of glutamatergic transmission and energy metabolism in neurons. J Neurochem. 2009 Mar; 108(6):1595-606. PMID: 19166514.
      View in: PubMed
    21. Dhar SS, Wong-Riley MT. Coupling of energy metabolism and synaptic transmission at the transcriptional level: role of nuclear respiratory factor 1 in regulating both cytochrome c oxidase and NMDA glutamate receptor subunit genes. J Neurosci. 2009 Jan 14; 29(2):483-92. PMID: 19144849.
      View in: PubMed
    22. Dhar SS, Ongwijitwat S, Wong-Riley MT. Nuclear respiratory factor 1 regulates all ten nuclear-encoded subunits of cytochrome c oxidase in neurons. J Biol Chem. 2008 Feb 08; 283(6):3120-9. PMID: 18077450.
      View in: PubMed
    23. JARID1D is a suppressor and prognostic marker of prostate cancer invasion and metastasis. Cancer Research. 76:831-843.
    24. An essential role for UTX in resolution and activation of bivalent promoters. Nucleic Acids Research. 44:3659-3674.
    25. ZMYND8 Reads the Dual Histone Mark H3K4me1-H3K14ac to Antagonize the Expression of Metastasis-Linked Genes. Molecular Cell.
    26. Erratum. Journal of Neurochemistry. 114:1241.
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