PABLO C OKHUYSEN

TitleProfessor
InstitutionMD Anderson
DepartmentInfectious Diseases, Infection Control, and Employee Health
Address1901 East Road
Houston TX 77054-3005
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Handley G, Hasbun R, Okhuysen P. Human herpesvirus 6 and central nervous system disease in oncology patients: A retrospective case series and literature review. J Clin Virol. 2021 Jan 28; 136:104740. PMID: 33548682.
      Citations:    Fields:    
    2. Viola GM, Malek AE, Rosen LB, DiNardo AR, Nishiguchi T, Okhuysen PC, Holland SM, Kontoyiannis DP. Disseminated cryptococcosis and anti-granulocyte-macrophage colony-stimulating factor autoantibodies: An underappreciated association. Mycoses. 2021 Jan 21. PMID: 33476401.
      Citations:    Fields:    
    3. Rajan A, Robertson MJ, Carter HE, Poole NM, Clark JR, Green SI, Criss ZK, Zhao B, Karandikar U, Xing Y, Margalef-Català M, Jain N, Wilson RL, Bai F, Hyser JM, Petrosino J, Shroyer NF, Blutt SE, Coarfa C, Song X, Prasad BV, Amieva MR, Grande-Allen J, Estes MK, Okhuysen PC, Maresso AW. Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. PLoS Pathog. 2020 09; 16(9):e1008851. PMID: 32986782.
      Citations: 2     Fields:    Translation:HumansCells
    4. Chakravarti D, Hu B, Mao X, Rashid A, Li J, Li J, Liao WT, Whitley EM, Dey P, Hou P, LaBella KA, Chang A, Wang G, Spring DJ, Deng P, Zhao D, Liang X, Lan Z, Lin Y, Sarkar S, Terranova C, Deribe YL, Blutt SE, Okhuysen P, Zhang J, Vilar E, Nielsen OH, Dupont A, Younes M, Patel KR, Shroyer NF, Rai K, Estes MK, Wang YA, Bertuch AA, DePinho RA. Telomere dysfunction activates YAP1 to drive tissue inflammation. Nat Commun. 2020 09 21; 11(1):4766. PMID: 32958778.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Olvera A, Carter H, Rajan A, Carlin LG, Yu X, Zeng XL, Shelburne S, Bhatti M, Blutt SE, Shroyer NF, Jenq R, Estes MK, Maresso A, Okhuysen PC. Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients. Clin Infect Dis. 2020 Sep 15. PMID: 32930708.
      Citations:    Fields:    
    6. Yepez Guevara EA, Aitken SL, Olvera AV, Carlin L, Fernandes KE, Bhatti MM, Garey KW, Adachi J, Okhuysen PC. Clostridioides difficile infection in cancer and immunocompromised patients: Relevance of a two-step diagnostic algorithm and infecting ribotypes on clinical outcomes. Clin Infect Dis. 2020 Aug 17. PMID: 32803229.
      Citations:    Fields:    
    7. Abu-Sbeih H, Ali FS, Chen E, Mallepally N, Luo W, Lu Y, Foo WC, Qiao W, Okhuysen PC, Adachi JA, Hachem RY, Altan M, Jenq RR, Wang Y. Neutropenic Enterocolitis: Clinical Features and Outcomes. Dis Colon Rectum. 2020 03; 63(3):381-388. PMID: 31842164.
      Citations: 1     Fields:    Translation:Humans
    8. Mitra A, Grossman Biegert GW, Delgado AY, Karpinets TV, Solley TN, Mezzari MP, Yoshida-Court K, Petrosino JF, Mikkelson MD, Lin L, Eifel P, Zhang J, Ramondetta LM, Jhingran A, Sims TT, Schmeler K, Okhuysen P, Colbert LE, Klopp AH. Microbial Diversity and Composition Is Associated with Patient-Reported Toxicity during Chemoradiation Therapy for Cervical Cancer. Int J Radiat Oncol Biol Phys. 2020 05 01; 107(1):163-171. PMID: 31987960.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    9. Zhang X, Browman G, Siu W, Basen-Engquist KM, Hanash SM, Hoffman KL, Okhuysen PC, Scheet P, Petrosino JF, Kopetz S, Daniel CR. The BE GONE trial study protocol: a randomized crossover dietary intervention of dry beans targeting the gut microbiome of overweight and obese patients with a history of colorectal polyps or cancer. BMC Cancer. 2019 Dec 18; 19(1):1233. PMID: 31852462.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    10. Abu-Sbeih H, Herrera LN, Tang T, Altan M, Chaftari AM, Okhuysen PC, Jenq RR, Wang Y. Correction to: Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis. J Immunother Cancer. 2019 Dec 17; 7(1):352. PMID: 31847892.
      Citations:    Fields:    
    11. Kuhlmann FM, Martin J, Hazen TH, Vickers TJ, Pashos M, Okhuysen PC, Gómez-Duarte OG, Cebelinski E, Boxrud D, Del Canto F, Vidal R, Qadri F, Mitreva M, Rasko DA, Fleckenstein JM. Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli. PLoS Negl Trop Dis. 2019 11; 13(11):e0007825. PMID: 31756188.
      Citations: 2     Fields:    Translation:HumansCells
    12. Abu-Sbeih H, Tang T, Ali FS, Luo W, Neelapu SS, Westin JR, Okhuysen PC, Foo WC, Curry JL, Richards DM, Ge PS, Wang Y. Gastrointestinal Adverse Events Observed After Chimeric Antigen Receptor T-Cell Therapy. Am J Clin Oncol. 2019 10; 42(10):789-796. PMID: 31478934.
      Citations: 2     Fields:    Translation:Humans
    13. Abu-Sbeih H, Herrera LN, Tang T, Altan M, Chaftari AP, Okhuysen PC, Jenq RR, Wang Y. Impact of antibiotic therapy on the development and response to treatment of immune checkpoint inhibitor-mediated diarrhea and colitis. J Immunother Cancer. 2019 09 05; 7(1):242. PMID: 31488205.
      Citations: 5     Fields:    Translation:Humans
    14. Galloway-Peña JR, Peterson CB, Malik F, Sahasrabhojane PV, Shah DP, Brumlow CE, Carlin LG, Chemaly RF, Im JS, Rondon G, Felix E, Veillon L, Lorenzi PL, Alousi AM, Jenq RR, Kontoyiannis DP, Shpall EJ, Shelburne SA, Okhuysen PC. Fecal Microbiome, Metabolites, and Stem Cell Transplant Outcomes: A Single-Center Pilot Study. Open Forum Infect Dis. 2019 May; 6(5):ofz173. PMID: 31065565.
      Citations:    
    15. Wang EW, Bhatti M, Cantu S, Okhuysen PC. Diagnosis of Yersinia enterocolitica Infection in Cancer Patients With Diarrhea in the Era of Molecular Diagnostics for Gastrointestinal Infections. Open Forum Infect Dis. 2019 Apr; 6(4):ofz116. PMID: 31049362.
      Citations:    
    16. Abu-Sbeih H, Choi K, Tran CN, Wang X, Lum P, Shuttlesworth G, Stroehlein JR, Okhuysen PC, Wang Y. Recurrent Clostridium difficile infection is associated with treatment failure and prolonged illness in cancer patients. Eur J Gastroenterol Hepatol. 2019 01; 31(1):128-134. PMID: 30339561.
      Citations: 1     Fields:    Translation:Humans
    17. Yalamanchili H, Dandachi D, Okhuysen PC. Use and Interpretation of Enteropathogen Multiplex Nucleic Acid Amplification Tests in Patients With Suspected Infectious Diarrhea. Gastroenterol Hepatol (N Y). 2018 Nov; 14(11):646-652. PMID: 30538605.
      Citations:    
    18. Rajan A, Vela L, Zeng XL, Yu X, Shroyer N, Blutt SE, Poole NM, Carlin LG, Nataro JP, Estes MK, Okhuysen PC, Maresso AW. Novel Segment- and Host-Specific Patterns of Enteroaggregative Escherichia coli Adherence to Human Intestinal Enteroids. mBio. 2018 02 20; 9(1). PMID: 29463660.
      Citations: 19     Fields:    Translation:HumansCells
    19. Chao AW, Bhatti M, DuPont HL, Nataro JP, Carlin LG, Okhuysen PC. Clinical features and molecular epidemiology of diarrheagenic Escherichia coli pathotypes identified by fecal gastrointestinal multiplex nucleic acid amplification in patients with cancer and diarrhea. Diagn Microbiol Infect Dis. 2017 Nov; 89(3):235-240. PMID: 28931467.
      Citations: 6     Fields:    Translation:HumansCells
    20. Ghosh N, Malik FA, Daver RG, Vanichanan J, Okhuysen PC. Viral associated diarrhea in immunocompromised and cancer patients at a large comprehensive cancer center: a 10-year retrospective study. Infect Dis (Lond). 2017 Feb; 49(2):113-119. PMID: 27620005.
      Citations: 2     Fields:    Translation:HumansCells
    21. Chappell CL, Darkoh C, Shimmin L, Farhana N, Kim DK, Okhuysen PC, Hixson J. Fecal Indole as a Biomarker of Susceptibility to Cryptosporidium Infection. Infect Immun. 2016 08; 84(8):2299-306. PMID: 27245413.
      Citations: 8     Fields:    Translation:HumansAnimals
    22. Darkoh C, Chappell C, Gonzales C, Okhuysen P. A rapid and specific method for the detection of indole in complex biological samples. Appl Environ Microbiol. 2015 Dec; 81(23):8093-7. PMID: 26386049.
      Citations: 17     Fields:    Translation:HumansCellsPHPublic Health
    23. Chappell CL, Okhuysen PC, Langer-Curry RC, Lupo PJ, Widmer G, Tzipori S. Cryptosporidium muris: infectivity and illness in healthy adult volunteers. Am J Trop Med Hyg. 2015 Jan; 92(1):50-5. PMID: 25311695.
      Citations: 6     Fields:    Translation:HumansAnimals
    24. Nair P, Okhuysen PC, Jiang ZD, Carlin LG, Belkind-Gerson J, Flores J, Paredes M, DuPont HL. Persistent abdominal symptoms in US adults after short-term stay in Mexico. J Travel Med. 2014 May-Jun; 21(3):153-8. PMID: 24621006.
      Citations: 8     Fields:    Translation:HumansCells
    25. Ajami NJ, Kavanagh OV, Ramani S, Crawford SE, Atmar RL, Jiang ZD, Okhuysen PC, Estes MK, DuPont HL. Seroepidemiology of norovirus-associated travelers' diarrhea. J Travel Med. 2014 Jan-Feb; 21(1):6-11. PMID: 24383649.
      Citations: 9     Fields:    Translation:HumansCellsPHPublic Health
    26. Mahale P, Okhuysen PC, Torres HA. Does chemotherapy cause viral relapse in cancer patients with hepatitis C infection successfully treated with antivirals? Clin Gastroenterol Hepatol. 2014 Jun; 12(6):1051-4.e1. PMID: 24211293.
      Citations: 4     Fields:    Translation:HumansCells
    27. Cabada MM, Okhuysen PC, White AC. Enteropathogens and chronic illness in returning travelers. N Engl J Med. 2013 08 22; 369(8):783. PMID: 23964950.
      Citations: 1     Fields:    Translation:HumansAnimals
    28. McGrath DM, Barbu EM, Driessen WH, Lasco TM, Tarrand JJ, Okhuysen PC, Kontoyiannis DP, Sidman RL, Pasqualini R, Arap W. Mechanism of action and initial evaluation of a membrane active all-D-enantiomer antimicrobial peptidomimetic. Proc Natl Acad Sci U S A. 2013 Feb 26; 110(9):3477-82. PMID: 23345420.
      Citations: 15     Fields:    Translation:Cells
    29. Flores-Figueroa J, Okhuysen PC, von Sonnenburg F, DuPont HL, Libman MD, Keystone JS, Hale DC, Burchard G, Han PV, Wilder-Smith A, Freedman DO. Patterns of illness in travelers visiting Mexico and Central America: the GeoSentinel experience. Clin Infect Dis. 2011 Sep; 53(6):523-31. PMID: 21832261.
      Citations: 10     Fields:    Translation:HumansPHPublic Health
    30. Flores J, Dupont HL, Jiang ZD, Okhuysen PC, Melendez-Romero JH, Gonzalez-Estrada A, Carrillo I, Paredes M. A randomized, double-blind, pilot study of rifaximin 550 mg versus placebo in the prevention of travelers' diarrhea in Mexico during the dry season. J Travel Med. 2011 Sep-Oct; 18(5):333-6. PMID: 21896097.
      Citations: 9     Fields:    Translation:Humans
    31. Chappell CL, Okhuysen PC, Langer-Curry RC, Akiyoshi DE, Widmer G, Tzipori S. Cryptosporidium meleagridis: infectivity in healthy adult volunteers. Am J Trop Med Hyg. 2011 Aug; 85(2):238-42. PMID: 21813841.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    32. Mohamed JA, DuPont HL, Flores J, Palur H, Nair P, Jiang ZD, Guo D, Belkind-Gerson J, Okhuysen PC. Single nucleotide polymorphisms in the promoter of the gene encoding the lipopolysaccharide receptor CD14 are associated with bacterial diarrhea in US and Canadian travelers to Mexico. Clin Infect Dis. 2011 Jun; 52(11):1332-41. PMID: 21596674.
      Citations: 14     Fields:    Translation:HumansCells
    33. Cozzi-Lepri A, French MA, Baxter J, Okhuysen P, Plana M, Neuhaus J, Landay A. Resumption of HIV replication is associated with monocyte/macrophage derived cytokine and chemokine changes: results from a large international clinical trial. AIDS. 2011 Jun 01; 25(9):1207-17. PMID: 21505304.
      Citations: 16     Fields:    Translation:HumansCells
    34. Paredes-Paredes M, Okhuysen PC, Flores J, Mohamed JA, Padda RS, Gonzalez-Estrada A, Haley CA, Carlin LG, Nair P, DuPont HL. Seasonality of diarrheagenic Escherichia coli pathotypes in the US students acquiring diarrhea in Mexico. J Travel Med. 2011 Mar-Apr; 18(2):121-5. PMID: 21366796.
      Citations: 12     Fields:    Translation:HumansCells
    35. Villa NA, Okhuysen PC, Flores-Figueroa J, Jiang ZD, Belkind-Gerson J, Paredes M, Mohamed JA, Nair P, Carlin L, DuPont HL. Campylobacter jejuni is not an important pathogen as a cause of diarrhea in US travelers to Mexico. J Travel Med. 2011 Jan-Feb; 18(1):56-8. PMID: 21199144.
      Citations: 1     Fields:    Translation:HumansCells
    36. Okhuysen PC, Dupont HL. Enteroaggregative Escherichia coli (EAEC): a cause of acute and persistent diarrhea of worldwide importance. J Infect Dis. 2010 Aug 15; 202(4):503-5. PMID: 20594108.
      Citations: 25     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    37. Ajami N, Koo H, Darkoh C, Atmar RL, Okhuysen PC, Jiang ZD, Flores J, Dupont HL. Characterization of norovirus-associated traveler's diarrhea. Clin Infect Dis. 2010 Jul 15; 51(2):123-30. PMID: 20540620.
      Citations: 14     Fields:    Translation:HumansCells
    38. Ouyang-Latimer J, Ajami NJ, Jiang ZD, Okhuysen PC, Paredes M, Flores J, Dupont HL. Biochemical and genetic diversity of enterotoxigenic Escherichia coli associated with diarrhea in United States students in Cuernavaca and Guadalajara, Mexico, 2004-2007. J Infect Dis. 2010 Jun 15; 201(12):1831-8. PMID: 20443738.
      Citations: 5     Fields:    Translation:HumansCells
    39. Koo HL, Ajami NJ, Jiang ZD, Neill FH, Atmar RL, Ericsson CD, Okhuysen PC, Taylor DN, Bourgeois AL, Steffen R, DuPont HL. Noroviruses as a cause of diarrhea in travelers to Guatemala, India, and Mexico. J Clin Microbiol. 2010 May; 48(5):1673-6. PMID: 20305012.
      Citations: 15     Fields:    Translation:HumansCells
    40. Flores J, DuPont HL, Paredes-Paredes M, Aguirre-Garcia MM, Rojas A, Gonzalez A, Okhuysen PC. Pilot study of whole-blood gamma interferon response to the Vibrio cholerae toxin B subunit and resistance to enterotoxigenic Escherichia coli-associated diarrhea. Clin Vaccine Immunol. 2010 May; 17(5):879-81. PMID: 20219880.
      Citations:    Fields:    Translation:HumansCells
    41. Martinez-Sandoval F, Ericsson CD, Jiang ZD, Okhuysen PC, Romero JH, Hernandez N, Forbes WP, Shaw A, Bortey E, DuPont HL. Prevention of travelers' diarrhea with rifaximin in US travelers to Mexico. J Travel Med. 2010 Mar-Apr; 17(2):111-7. PMID: 20412178.
      Citations: 9     Fields:    Translation:Humans
    42. Flores J, Okhuysen PC. Genetics of susceptibility to infection with enteric pathogens. Curr Opin Infect Dis. 2009 Oct; 22(5):471-6. PMID: 19633551.
      Citations: 12     Fields:    Translation:HumansCells
    43. Mohamed JA, DuPont HL, Jiang ZD, Flores J, Carlin LG, Belkind-Gerson J, Martinez-Sandoval FG, Guo D, White AC, Okhuysen PC. A single-nucleotide polymorphism in the gene encoding osteoprotegerin, an anti-inflammatory protein produced in response to infection with diarrheagenic Escherichia coli, is associated with an increased risk of nonsecretory bacterial diarrhea in North American travelers to Mexico. J Infect Dis. 2009 Feb 15; 199(4):477-85. PMID: 19128145.
      Citations: 6     Fields:    Translation:HumansCells
    44. Flores J, Okhuysen PC. Enteroaggregative Escherichia coli infection. Curr Opin Gastroenterol. 2009 Jan; 25(1):8-11. PMID: 19114769.
      Citations: 15     Fields:    Translation:HumansCellsPHPublic Health
    45. Nair P, Mohamed JA, DuPont HL, Figueroa JF, Carlin LG, Jiang ZD, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. Epidemiology of cryptosporidiosis in North American travelers to Mexico. Am J Trop Med Hyg. 2008 Aug; 79(2):210-4. PMID: 18689626.
      Citations: 3     Fields:    Translation:HumansAnimals
    46. Nallapareddy SR, Singh KV, Okhuysen PC, Murray BE. A functional collagen adhesin gene, acm, in clinical isolates of Enterococcus faecium correlates with the recent success of this emerging nosocomial pathogen. Infect Immun. 2008 Sep; 76(9):4110-9. PMID: 18591238.
      Citations: 33     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    47. Flores J, DuPont HL, Lee SA, Belkind-Gerson J, Paredes M, Mohamed JA, Armitige LY, Guo DC, Okhuysen PC. Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico. Clin Vaccine Immunol. 2008 Aug; 15(8):1194-8. PMID: 18579697.
      Citations: 11     Fields:    Translation:HumansCells
    48. Frech SA, Dupont HL, Bourgeois AL, McKenzie R, Belkind-Gerson J, Figueroa JF, Okhuysen PC, Guerrero NH, Martinez-Sandoval FG, Meléndez-Romero JH, Jiang ZD, Asturias EJ, Halpern J, Torres OR, Hoffman AS, Villar CP, Kassem RN, Flyer DC, Andersen BH, Kazempour K, Breisch SA, Glenn GM. Use of a patch containing heat-labile toxin from Escherichia coli against travellers' diarrhoea: a phase II, randomised, double-blind, placebo-controlled field trial. Lancet. 2008 Jun 14; 371(9629):2019-25. PMID: 18554712.
      Citations: 46     Fields:    Translation:HumansCTClinical Trials
    49. Lupo PJ, Langer-Curry RC, Robinson M, Okhuysen PC, Chappell CL. Cryptosporidium muris in a Texas canine population. Am J Trop Med Hyg. 2008 Jun; 78(6):917-21. PMID: 18541769.
      Citations: 8     Fields:    Translation:AnimalsCells
    50. Grimes KA, Mohamed JA, Dupont HL, Padda RS, Jiang ZD, Flores J, Belkind-Gerson J, Martinez-Sandoval FG, Okhuysen PC. PCR-based assay using occult blood detection cards for detection of diarrheagenic Escherichia coli in specimens from U.S. travelers to Mexico with acute diarrhea. J Clin Microbiol. 2008 Jul; 46(7):2227-30. PMID: 18480224.
      Citations: 11     Fields:    Translation:HumansCells
    51. Flores J, DuPont HL, Jiang ZD, Belkind-Gerson J, Mohamed JA, Carlin LG, Padda RS, Paredes M, Martinez-Sandoval JF, Villa NA, Okhuysen PC. Enterotoxigenic Escherichia coli heat-labile toxin seroconversion in US travelers to Mexico. J Travel Med. 2008 May-Jun; 15(3):156-61. PMID: 18494692.
      Citations: 6     Fields:    Translation:Humans
    52. Huang DB, Brown EL, DuPont HL, Cerf J, Carlin L, Flores J, Belkind-Gerson J, Nataro JP, Okhuysen PC. Seroprevalence of the enteroaggregative Escherichia coli virulence factor dispersin among USA travellers to Cuernavaca, Mexico: a pilot study. J Med Microbiol. 2008 Apr; 57(Pt 4):476-479. PMID: 18349368.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    53. Planque S, Mitsuda Y, Taguchi H, Salas M, Morris MK, Nishiyama Y, Kyle R, Okhuysen P, Escobar M, Hunter R, Sheppard HW, Hanson C, Paul S. Characterization of gp120 hydrolysis by IgA antibodies from humans without HIV infection. AIDS Res Hum Retroviruses. 2007 Dec; 23(12):1541-54. PMID: 18160012.
      Citations: 18     Fields:    Translation:HumansCells
    54. Huang DB, Mohamed JA, Nataro JP, DuPont HL, Jiang ZD, Okhuysen PC. Virulence characteristics and the molecular epidemiology of enteroaggregative Escherichia coli isolates from travellers to developing countries. J Med Microbiol. 2007 Oct; 56(Pt 10):1386-1392. PMID: 17893178.
      Citations: 20     Fields:    Translation:HumansCells
    55. Ericsson CD, DuPont HL, Okhuysen PC, Jiang ZD, DuPont MW. Loperamide plus azithromycin more effectively treats travelers' diarrhea in Mexico than azithromycin alone. J Travel Med. 2007 Sep-Oct; 14(5):312-9. PMID: 17883462.
      Citations: 11     Fields:    Translation:Humans
    56. Jiang ZD, Garey KW, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M, DuPont HL. Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrhea. Clin Gastroenterol Hepatol. 2007 Aug; 5(8):964-8. PMID: 17618838.
      Citations: 18     Fields:    Translation:HumansCells
    57. Dupont HL, Jiang ZD, Belkind-Gerson J, Okhuysen PC, Ericsson CD, Ke S, Huang DB, Dupont MW, Adachi JA, De La Cabada FJ, Taylor DN, Jaini S, Martinez Sandoval F. Treatment of travelers' diarrhea: randomized trial comparing rifaximin, rifaximin plus loperamide, and loperamide alone. Clin Gastroenterol Hepatol. 2007 Apr; 5(4):451-6. PMID: 17382603.
      Citations: 25     Fields:    Translation:Humans
    58. Mohamed JA, DuPont HL, Jiang ZD, Belkind-Gerson J, Figueroa JF, Armitige LY, Tsai A, Nair P, Martinez-Sandoval FJ, Guo DC, Hayes P, Okhuysen PC. A novel single-nucleotide polymorphism in the lactoferrin gene is associated with susceptibility to diarrhea in North American travelers to Mexico. Clin Infect Dis. 2007 Apr 01; 44(7):945-52. PMID: 17342646.
      Citations: 21     Fields:    Translation:Humans
    59. Aguirre-García MM, Okhuysen PC. Cryptosporidium parvum: identification and characterization of an acid phosphatase. Parasitol Res. 2007 Jun; 101(1):85-9. PMID: 17252269.
      Citations: 5     Fields:    Translation:Animals
    60. DuPont HL, Haake R, Taylor DN, Ericsson CD, Jiang ZD, Okhuysen PC, Steffen R. Rifaximin treatment of pathogen-negative travelers' diarrhea. J Travel Med. 2007 Jan-Feb; 14(1):16-9. PMID: 17241249.
      Citations: 8     Fields:    Translation:Humans
    61. Mohamed JA, Huang DB, Jiang ZD, DuPont HL, Nataro JP, Belkind-Gerson J, Okhuysen PC. Association of putative enteroaggregative Escherichia coli virulence genes and biofilm production in isolates from travelers to developing countries. J Clin Microbiol. 2007 Jan; 45(1):121-6. PMID: 17093030.
      Citations: 24     Fields:    Translation:HumansCells
    62. Chappell CL, Okhuysen PC, Langer-Curry R, Widmer G, Akiyoshi DE, Tanriverdi S, Tzipori S. Cryptosporidium hominis: experimental challenge of healthy adults. Am J Trop Med Hyg. 2006 Nov; 75(5):851-7. PMID: 17123976.
      Citations: 49     Fields:    Translation:HumansAnimals
    63. Wang HC, Dann SM, Okhuysen PC, Lewis DE, Chappell CL, Adler DG, White AC. High levels of CXCL10 are produced by intestinal epithelial cells in AIDS patients with active cryptosporidiosis but not after reconstitution of immunity. Infect Immun. 2007 Jan; 75(1):481-7. PMID: 17043107.
      Citations: 11     Fields:    Translation:HumansAnimals
    64. Huang DB, Mohanty A, DuPont HL, Okhuysen PC, Chiang T. A review of an emerging enteric pathogen: enteroaggregative Escherichia coli. J Med Microbiol. 2006 Oct; 55(Pt 10):1303-1311. PMID: 17005776.
      Citations: 45     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    65. Huang DB, Nataro JP, DuPont HL, Kamat PP, Mhatre AD, Okhuysen PC, Chiang T. Enteroaggregative Escherichia coli is a cause of acute diarrheal illness: a meta-analysis. Clin Infect Dis. 2006 Sep 01; 43(5):556-63. PMID: 16886146.
      Citations: 44     Fields:    Translation:Humans
    66. Ko G, Jiang ZD, Okhuysen PC, DuPont HL. Fecal cytokines and markers of intestinal inflammation in international travelers with diarrhea due to Noroviruses. J Med Virol. 2006 Jun; 78(6):825-8. PMID: 16628572.
      Citations: 13     Fields:    Translation:HumansCells
    67. Jiang ZD, DuPont HL, Garey K, Price M, Graham G, Okhuysen P, Dao-Tran T, LaRocco M. A common polymorphism in the interleukin 8 gene promoter is associated with Clostridium difficile diarrhea. Am J Gastroenterol. 2006 May; 101(5):1112-6. PMID: 16573784.
      Citations: 26     Fields:    Translation:HumansCells
    68. DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. Antibacterial chemoprophylaxis in the prevention of traveler's diarrhea: evaluation of poorly absorbed oral rifaximin. Clin Infect Dis. 2005 Dec 01; 41 Suppl 8:S571-6. PMID: 16267721.
      Citations: 3     Fields:    Translation:Humans
    69. Ko G, Garcia C, Jiang ZD, Okhuysen PC, Belkind-Gerson J, Glass RI, DuPont HL. Noroviruses as a cause of traveler's diarrhea among students from the United States visiting Mexico. J Clin Microbiol. 2005 Dec; 43(12):6126-9. PMID: 16333110.
      Citations: 17     Fields:    Translation:HumansCells
    70. Okhuysen PC. Current concepts in travelers' diarrhea: epidemiology, antimicrobial resistance and treatment. Curr Opin Infect Dis. 2005 Dec; 18(6):522-6. PMID: 16258326.
      Citations: 2     Fields:    Translation:HumansCells
    71. Mohr JF, McKinnon PS, Peymann PJ, Kenton I, Septimus E, Okhuysen PC. A retrospective, comparative evaluation of dysglycemias in hospitalized patients receiving gatifloxacin, levofloxacin, ciprofloxacin, or ceftriaxone. Pharmacotherapy. 2005 Oct; 25(10):1303-9. PMID: 16185173.
      Citations: 14     Fields:    Translation:Humans
    72. Okhuysen PC, Chappell CL, Lewis DE, Robinson P, White AC. Treatment of chronic cryptosporidiosis in AIDS with rIL-12 induces an immune response associated with improvement but severe side-effects. AIDS. 2005 Aug 12; 19(12):1333-4. PMID: 16052094.
      Citations: 1     Fields:    Translation:Humans
    73. DuPont HL, Jiang ZD, Okhuysen PC, Ericsson CD, de la Cabada FJ, Ke S, DuPont MW, Martinez-Sandoval F. A randomized, double-blind, placebo-controlled trial of rifaximin to prevent travelers' diarrhea. Ann Intern Med. 2005 May 17; 142(10):805-12. PMID: 15897530.
      Citations: 49     Fields:    Translation:HumansCTClinical Trials
    74. Kjos SA, Jenkins M, Okhuysen PC, Chappell CL. Evaluation of recombinant oocyst protein CP41 for detection of cryptosporidium-specific antibodies. Clin Diagn Lab Immunol. 2005 Feb; 12(2):268-72. PMID: 15699421.
      Citations: 2     Fields:    Translation:HumansAnimals
    75. Huang DB, Chappell C, Okhuysen PC. Cryptosporidiosis in children. Semin Pediatr Infect Dis. 2004 Oct; 15(4):253-9. PMID: 15494949.
      Citations: 20     Fields:    Translation:HumansAnimals
    76. Okhuysen PC, Jiang ZD, Carlin L, Forbes C, DuPont HL. Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico. Am J Gastroenterol. 2004 Sep; 99(9):1774-8. PMID: 15330917.
      Citations: 52     Fields:    Translation:Humans
    77. Huang DB, DuPont HL, Jiang ZD, Carlin L, Okhuysen PC. Interleukin-8 response in an intestinal HCT-8 cell line infected with enteroaggregative and enterotoxigenic Escherichia coli. Clin Diagn Lab Immunol. 2004 May; 11(3):548-51. PMID: 15138180.
      Citations: 18     Fields:    Translation:HumansCells
    78. Roberts JC, Singh KV, Okhuysen PC, Murray BE. Molecular epidemiology of the fsr locus and of gelatinase production among different subsets of Enterococcus faecalis isolates. J Clin Microbiol. 2004 May; 42(5):2317-20. PMID: 15131223.
      Citations: 15     Fields:    Translation:HumansCells
    79. Okhuysen PC, Rogers GA, Crisanti A, Spano F, Huang DB, Chappell CL, Tzipori S. Antibody response of healthy adults to recombinant thrombospondin-related adhesive protein of cryptosporidium 1 after experimental exposure to cryptosporidium oocysts. Clin Diagn Lab Immunol. 2004 Mar; 11(2):235-8. PMID: 15013968.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    80. Huang DB, Okhuysen PC, Jiang ZD, DuPont HL. Enteroaggregative Escherichia coli: an emerging enteric pathogen. Am J Gastroenterol. 2004 Feb; 99(2):383-9. PMID: 15046233.
      Citations: 20     Fields:    Translation:HumansCells
    81. White AC, Robinson P, Okhuysen PC. Human studies provide insight into the pathogenesis, immunology, and treatment of cryptosporidiosis. Clin Infect Dis. 2003 Oct 01; 37(7):989; author reply 989-90. PMID: 13130414.
      Citations: 1     Fields:    Translation:HumansAnimals
    82. Jiang ZD, Okhuysen PC, Guo DC, He R, King TM, DuPont HL, Milewicz DM. Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor region. J Infect Dis. 2003 Aug 15; 188(4):506-11. PMID: 12898436.
      Citations: 51     Fields:    Translation:HumansCells
    83. Robinson P, Okhuysen PC, Chappell CL, Weinstock JV, Lewis DE, Actor JK, White AC. Substance P expression correlates with severity of diarrhea in cryptosporidiosis. J Infect Dis. 2003 Jul 15; 188(2):290-6. PMID: 12854086.
      Citations: 9     Fields:    Translation:HumansAnimals
    84. Alcantara CS, Yang CH, Steiner TS, Barrett LJ, Lima AA, Chappell CL, Okhuysen PC, White AC, Guerrant RL. Interleukin-8, tumor necrosis factor-alpha, and lactoferrin in immunocompetent hosts with experimental and Brazilian children with acquired cryptosporidiosis. Am J Trop Med Hyg. 2003 Mar; 68(3):325-8. PMID: 12685639.
      Citations: 18     Fields:    Translation:Humans
    85. Millership JJ, Chappell C, Okhuysen PC, Snowden KF. Characterization of aminopeptidase activity from three species of microsporidia: Encephalitozoon cuniculi, Encephalitozoon hellem, and Vittaforma corneae. J Parasitol. 2002 Oct; 88(5):843-8. PMID: 12435118.
      Citations: 5     Fields:    Translation:AnimalsCells
    86. Chappell CL, Okhuysen PC. Cryptosporidiosis. Curr Opin Infect Dis. 2002 Oct; 15(5):523-7. PMID: 12686887.
      Citations: 18     Fields:    Translation:HumansAnimals
    87. Nannini EC, Okhuysen PC. HIV1 and the gut in the era of highly active antiretroviral therapy. Curr Gastroenterol Rep. 2002 Oct; 4(5):392-8. PMID: 12228041.
      Citations: 15     Fields:    Translation:HumansCells
    88. Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose-response studies: variation between hosts. Risk Anal. 2002 Jun; 22(3):475-85. PMID: 12088227.
      Citations: 5     Fields:    Translation:HumansAnimals
    89. Okhuysen PC, Chappell CL. Cryptosporidium virulence determinants--are we there yet? Int J Parasitol. 2002 May; 32(5):517-25. PMID: 11943224.
      Citations: 16     Fields:    Translation:HumansAnimals
    90. Okhuysen PC, Rich SM, Chappell CL, Grimes KA, Widmer G, Feng X, Tzipori S. Infectivity of a Cryptosporidium parvum isolate of cervine origin for healthy adults and interferon-gamma knockout mice. J Infect Dis. 2002 May 01; 185(9):1320-5. PMID: 12001050.
      Citations: 26     Fields:    Translation:HumansAnimals
    91. Padda RS, Tsai A, Chappell CL, Okhuysen PC. Molecular cloning and analysis of the Cryptosporidium parvum aminopeptidase N gene. Int J Parasitol. 2002 Feb; 32(2):187-97. PMID: 11812496.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    92. Teunis PF, Chappell CL, Okhuysen PC. Cryptosporidium dose response studies: variation between isolates. Risk Anal. 2002 Feb; 22(1):175-83. PMID: 12017359.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    93. Millership JJ, Chappell CL, Okhuysen PC, Snowden KF. Characterization of a cytosolic aminopeptidase from Encephalitozoon intestinalis. Parasitology. 2002 Jan; 124(Pt 1):1-7. PMID: 11811798.
      Citations: 1     Fields:    Translation:HumansAnimals
    94. Dasgupta A, Okhuysen PC. Pharmacokinetic and other drug interactions in patients with AIDS. Ther Drug Monit. 2001 Dec; 23(6):591-605. PMID: 11802090.
      Citations: 5     Fields:    Translation:Humans
    95. Messner MJ, Chappell CL, Okhuysen PC. Risk assessment for Cryptosporidium: a hierarchical Bayesian analysis of human dose response data. Water Res. 2001 Nov; 35(16):3934-40. PMID: 12230176.
      Citations: 18     Fields:    Translation:HumansAnimals
    96. Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White AC. Expression of IL-15 and IL-4 in IFN-gamma-independent control of experimental human Cryptosporidium parvum infection. Cytokine. 2001 Jul 07; 15(1):39-46. PMID: 11509007.
      Citations: 10     Fields:    Translation:HumansAnimals
    97. Okhuysen PC. Traveler's diarrhea due to intestinal protozoa. Clin Infect Dis. 2001 Jul 01; 33(1):110-4. PMID: 11389503.
      Citations: 28     Fields:    Translation:HumansAnimals
    98. Okhuysen PC, Robinson P, Nguyen MT, Nannini EC, Lewis DE, Janecki A, Chappell CL, White AC. Jejunal cytokine response in AIDS patients with chronic cryptosporidiosis and during immune reconstitution. AIDS. 2001 Apr 13; 15(6):802-4. PMID: 11371698.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    99. Muller TB, Frost FJ, Craun GF, Calderon RL. Serological responses to Cryptosporidium infection. Infect Immun. 2001 Mar; 69(3):1974-5. PMID: 11253773.
      Citations: 2     Fields:    Translation:Humans
    100. Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Janecki A, White AC. Expression of tumor necrosis factor alpha and interleukin 1 beta in jejuna of volunteers after experimental challenge with Cryptosporidium parvum correlates with exposure but not with symptoms. Infect Immun. 2001 Feb; 69(2):1172-4. PMID: 11160015.
      Citations: 9     Fields:    Translation:HumansAnimals
    101. Millership JJ, Didier ES, Okhuysen PC, Maddry JA, Kwong CD, Chen X, Snowden KF. In vitro and in vivo evaluation of aminopeptidase inhibitors as antimicrosporidial therapies. J Eukaryot Microbiol. 2001; Suppl:95S-98S. PMID: 11906096.
      Citations: 1     Fields:    Translation:Animals
    102. Robinson P, Okhuysen PC, Chappell CL, Lewis DE, Shahab I, Lahoti S, White AC. Transforming growth factor beta1 is expressed in the jejunum after experimental Cryptosporidium parvum infection in humans. Infect Immun. 2000 Sep; 68(9):5405-7. PMID: 10948171.
      Citations: 8     Fields:    Translation:HumansAnimals
    103. Dann SM, Okhuysen PC, Salameh BM, DuPont HL, Chappell CL. Fecal antibodies to Cryptosporidium parvum in healthy volunteers. Infect Immun. 2000 Sep; 68(9):5068-74. PMID: 10948127.
      Citations: 8     Fields:    Translation:HumansAnimals
    104. White AC, Robinson P, Okhuysen PC, Lewis DE, Shahab I, Lahoti S, DuPont HL, Chappell CL. Interferon-gamma expression in jejunal biopsies in experimental human cryptosporidiosis correlates with prior sensitization and control of oocyst excretion. J Infect Dis. 2000 Feb; 181(2):701-9. PMID: 10669358.
      Citations: 17     Fields:    Translation:HumansAnimals
    105. Okhuysen PC, Chappell CL, Crabb JH, Sterling CR, DuPont HL. Virulence of three distinct Cryptosporidium parvum isolates for healthy adults. J Infect Dis. 1999 Oct; 180(4):1275-81. PMID: 10479158.
      Citations: 88     Fields:    Translation:HumansAnimals
    106. Okhuysen PC, White AC. Parasitic infections of the intestines. Curr Opin Infect Dis. 1999 Oct; 12(5):467-72. PMID: 17035813.
      Citations: 6     Fields:    
    107. Chappell CL, Okhuysen PC, Sterling CR, Wang C, Jakubowski W, Dupont HL. Infectivity of Cryptosporidium parvum in healthy adults with pre-existing anti-C. parvum serum immunoglobulin G. Am J Trop Med Hyg. 1999 Jan; 60(1):157-64. PMID: 9988341.
      Citations: 41     Fields:    Translation:HumansAnimals
    108. Moss DM, Chappell CL, Okhuysen PC, DuPont HL, Arrowood MJ, Hightower AW, Lammie PJ. The antibody response to 27-, 17-, and 15-kDa Cryptosporidium antigens following experimental infection in humans. J Infect Dis. 1998 Sep; 178(3):827-33. PMID: 9728553.
      Citations: 39     Fields:    Translation:HumansAnimals
    109. Frost FJ, Caun GF. Serologic response to human Cryptosporidium infections. Infect Immun. 1998 Aug; 66(8):4008-9. PMID: 9714611.
      Citations: 2     Fields:    Translation:HumansAnimals
    110. Okhuysen PC, Chappell CL, Crabb J, Valdez LM, Douglass ET, DuPont HL. Prophylactic effect of bovine anti-Cryptosporidium hyperimmune colostrum immunoglobulin in healthy volunteers challenged with Cryptosporidium parvum. Clin Infect Dis. 1998 Jun; 26(6):1324-9. PMID: 9636857.
      Citations: 16     Fields:    Translation:HumansAnimalsCTClinical Trials
    111. Okhuysen PC, Chappell CL, Sterling CR, Jakubowski W, DuPont HL. Susceptibility and serologic response of healthy adults to reinfection with Cryptosporidium parvum. Infect Immun. 1998 Feb; 66(2):441-3. PMID: 9453592.
      Citations: 38     Fields:    Translation:HumansAnimals
    112. Valdez LM, Dang H, Okhuysen PC, Chappell CL. Flow cytometric detection of Cryptosporidium oocysts in human stool samples. J Clin Microbiol. 1997 Aug; 35(8):2013-7. PMID: 9230372.
      Citations: 7     Fields:    Translation:HumansAnimals
    113. Valdez LM, Schwab P, Okhuysen PC, Rakita RM. Paradoxical subcutaneous tuberculous abscess. Clin Infect Dis. 1997 Apr; 24(4):734. PMID: 9145751.
      Citations: 5     Fields:    Translation:HumansCells
    114. Okhuysen PC, Chappell CL, Kettner C, Sterling CR. Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation. Antimicrob Agents Chemother. 1996 Dec; 40(12):2781-4. PMID: 9124840.
      Citations: 7     Fields:    Translation:AnimalsCells
    115. Chappell CL, Okhuysen PC, Sterling CR, DuPont HL. Cryptosporidium parvum: intensity of infection and oocyst excretion patterns in healthy volunteers. J Infect Dis. 1996 Jan; 173(1):232-6. PMID: 8537664.
      Citations: 35     Fields:    Translation:HumansAnimals
    116. Okhuysen PC, DuPont HL, Ericsson CD, Marani S, Martinez-Sandoval FG, Olesen MA, Ravelli GP. Zaldaride maleate (a new calmodulin antagonist) versus loperamide in the treatment of traveler's diarrhea: randomized, placebo-controlled trial. Clin Infect Dis. 1995 Aug; 21(2):341-4. PMID: 8562742.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    117. DuPont HL, Chappell CL, Sterling CR, Okhuysen PC, Rose JB, Jakubowski W. The infectivity of Cryptosporidium parvum in healthy volunteers. N Engl J Med. 1995 Mar 30; 332(13):855-9. PMID: 7870140.
      Citations: 158     Fields:    Translation:HumansAnimals
    118. Okhuysen PC, Jiang X, Ye L, Johnson PC, Estes MK. Viral shedding and fecal IgA response after Norwalk virus infection. J Infect Dis. 1995 Mar; 171(3):566-9. PMID: 7876602.
      Citations: 25     Fields:    Translation:HumansCells
    119. Okhuysen PC, DuPont HL, Sterling CR, Chappell CL. Arginine aminopeptidase, an integral membrane protein of the Cryptosporidium parvum sporozoite. Infect Immun. 1994 Oct; 62(10):4667-70. PMID: 7927738.
      Citations: 5     Fields:    Translation:Animals
    120. Okhuysen PC, Rex JH, Kapusta M, Fife C. Successful treatment of extensive posttraumatic soft-tissue and renal infections due to Apophysomyces elegans. Clin Infect Dis. 1994 Aug; 19(2):329-31. PMID: 7986910.
      Citations: 10     Fields:    Translation:HumansAnimals
    121. Okhuysen PC, Singh KV, Murray BE. Susceptibility of beta-lactamase-producing enterococci to piperacillin with tazobactam. Diagn Microbiol Infect Dis. 1993 Oct; 17(3):219-24. PMID: 8112031.
      Citations: 2     Fields:    Translation:HumansCells
    122. Okhuysen PC, Crane JK, Pappas J. St. Louis encephalitis in patients with human immunodeficiency virus infection. Clin Infect Dis. 1993 Jul; 17(1):140-1. PMID: 8353238.
      Citations: 2     Fields:    Translation:Humans
    123. Okhuysen PC, Ericsson CD. Travelers' diarrhea. Prevention and treatment. Med Clin North Am. 1992 Nov; 76(6):1357-73. PMID: 1405823.
      Citations: 5     Fields:    Translation:Humans
    124. Okhuysen PC, DuPont HL, Flores Lopez JF, Perez Castell J, Mathewson JJ. A comparative study of furazolidone and placebo in addition to oral rehydration in the treatment of acute infantile diarrhea. Scand J Gastroenterol Suppl. 1989; 169:39-46. PMID: 2694341.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
    125. A rapid and specific method for the detection of indole in complex biological samples. Applied and Environmental Microbiology. 81:8093-8097.
    126. Cryptosporidium Parvum. 19-49.
    127. Virulence of three distinct C. parvum isolates in healthy adults. Clinical Infectious Diseases. 25:428.
    128. Cryptosporidium Parvum Volunteer Study. 79-81.
    129. Erratum. Annals of Internal Medicine. 143:239.
    130. Erratum. Journal of Medical Microbiology. 56:142.
    131. Enterotoxigenic escherichia coli. 84-94.
    132. Enteroaggregative escherichia coli. 48-64.
    133. Fecal indole as a biomarker of susceptibility to cryptosporidium infection. Infection and Immunity. 84:2299-2306.
    134. Sporothrix schenckii. 2920-2924.
    135. Onchocerciasis in an expatriate living in Cameroon. Journal of Travel Medicine. 4:11-13.
    136. Post-diarrhea chronic intestinal symptoms and irritable bowel syndrome in North American travelers to Mexico [4]. American Journal of Gastroenterology. 100:729-730.
    137. Travelers' diarrhea, new insights. Journal of Clinical Gastroenterology. 41.
    138. Erratum. Clinical Infectious Diseases. 34:292.
    139. Evaluation of a New Latex Agglutination Test for Fecal Lactoferrin in Travelers' Diarrhea. Journal of Travel Medicine. 1:68-71.
    140. Traveler's diarrhea. Current Opinion in Gastroenterology. 9:103-106.
    141. Traveler's diarrhea. Current Opinion in Gastroenterology. 8:110-114.
    142. Circulating microRNAs in sera correlate with soluble biomarkers of immune activation but do not predict mortality in ART treated individuals with HIV-1 infection. PLoS One. 10.
    143. Viral associated diarrhea in immunocompromised and cancer patients at a large comprehensive cancer center. Infectious Diseases. 1-7.
    144. Intestinal tnfa in cryptosporidiosis. Journal of Investigative Medicine. 44.
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