YI XIAO

TitleInstructor
InstitutionMD Anderson
DepartmentMolecular & Cellular Oncology
Address1515 Holcombe Blvd
Houston TX 77030-4009
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Zou Q, Jin J, Xiao Y, Zhou X, Hu H, Cheng X, Kazimi N, Ullrich SE, Sun SC. T Cell Intrinsic USP15 Deficiency Promotes Excessive IFN-? Production and an Immunosuppressive Tumor Microenvironment in MCA-Induced Fibrosarcoma. Cell Rep. 2015 Dec 22; 13(11):2470-2479. PMID: 26686633.
      Citations: 9     Fields:    Translation:AnimalsCells
    2. Zou Q, Jin J, Xiao Y, Hu H, Zhou X, Jie Z, Xie X, Li JY, Cheng X, Sun SC. T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. J Exp Med. 2015 Jul 27; 212(8):1323-36. PMID: 26195727.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    3. Xiao Y, Jin J, Zou Q, Hu H, Cheng X, Sun SC. Peli1 negatively regulates type I interferon induction and antiviral immunity in the CNS. Cell Biosci. 2015; 5:34. PMID: 26131354.
      Citations:    
    4. Romano S, Xiao Y, Nakaya M, D'Angelillo A, Chang M, Jin J, Hausch F, Masullo M, Feng X, Romano MF, Sun SC. FKBP51 employs both scaffold and isomerase functions to promote NF-?B activation in melanoma. Nucleic Acids Res. 2015 Aug 18; 43(14):6983-93. PMID: 26101251.
      Citations: 19     Fields:    Translation:HumansCells
    5. Xu J, Acharya S, Sahin O, Zhang Q, Saito Y, Yao J, Wang H, Li P, Zhang L, Lowery FJ, Kuo WL, Xiao Y, Ensor J, Sahin AA, Zhang XH, Hung MC, Zhang JD, Yu D. 14-3-3? turns TGF-ß's function from tumor suppressor to metastasis promoter in breast cancer by contextual changes of Smad partners from p53 to Gli2. Cancer Cell. 2015 Feb 09; 27(2):177-92. PMID: 25670079.
      Citations: 47     Fields:    Translation:HumansCells
    6. Yu J, Zhou X, Chang M, Nakaya M, Chang JH, Xiao Y, Lindsey JW, Dorta-Estremera S, Cao W, Zal A, Zal T, Sun SC. Regulation of T-cell activation and migration by the kinase TBK1 during neuroinflammation. Nat Commun. 2015 Jan 21; 6:6074. PMID: 25606824.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    7. Jin J, Xiao Y, Hu H, Zou Q, Li Y, Gao Y, Ge W, Cheng X, Sun SC. Proinflammatory TLR signalling is regulated by a TRAF2-dependent proteolysis mechanism in macrophages. Nat Commun. 2015 Jan 07; 6:5930. PMID: 25565375.
      Citations: 25     Fields:    Translation:AnimalsCells
    8. Xiao Y, Jin J, Chang M, Nakaya M, Hu H, Zou Q, Zhou X, Brittain GC, Cheng X, Sun SC. TPL2 mediates autoimmune inflammation through activation of the TAK1 axis of IL-17 signaling. J Exp Med. 2014 Jul 28; 211(8):1689-702. PMID: 24980047.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    9. Nakaya M, Xiao Y, Zhou X, Chang JH, Chang M, Cheng X, Blonska M, Lin X, Sun SC. Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation. Immunity. 2014 May 15; 40(5):692-705. PMID: 24792914.
      Citations: 164     Fields:    Translation:HumansAnimalsCells
    10. Zou Q, Jin J, Hu H, Li HS, Romano S, Xiao Y, Nakaya M, Zhou X, Cheng X, Yang P, Lozano G, Zhu C, Watowich SS, Ullrich SE, Sun SC. USP15 stabilizes MDM2 to mediate cancer-cell survival and inhibit antitumor T cell responses. Nat Immunol. 2014 Jun; 15(6):562-70. PMID: 24777531.
      Citations: 57     Fields:    Translation:HumansAnimalsCells
    11. Jin J, Hu H, Li HS, Yu J, Xiao Y, Brittain GC, Zou Q, Cheng X, Mallette FA, Watowich SS, Sun SC. Noncanonical NF-?B pathway controls the production of type I interferons in antiviral innate immunity. Immunity. 2014 Mar 20; 40(3):342-54. PMID: 24656046.
      Citations: 33     Fields:    Translation:AnimalsCells
    12. Chang JH, Hu H, Jin J, Puebla-Osorio N, Xiao Y, Gilbert BE, Brink R, Ullrich SE, Sun SC. TRAF3 regulates the effector function of regulatory T cells and humoral immune responses. J Exp Med. 2014 Jan 13; 211(1):137-51. PMID: 24378539.
      Citations: 31     Fields:    Translation:AnimalsCells
    13. Rehman SK, Li SH, Wyszomierski SL, Wang Q, Li P, Sahin O, Xiao Y, Zhang S, Xiong Y, Yang J, Wang H, Guo H, Zhang JD, Medina D, Muller WJ, Yu D. 14-3-3? orchestrates mammary tumor onset and progression via miR-221-mediated cell proliferation. Cancer Res. 2014 Jan 01; 74(1):363-373. PMID: 24197133.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    14. Xiao Y, Jin J, Chang M, Chang JH, Hu H, Zhou X, Brittain GC, Stansberg C, Torkildsen Ø, Wang X, Brink R, Cheng X, Sun SC. Peli1 promotes microglia-mediated CNS inflammation by regulating Traf3 degradation. Nat Med. 2013 May; 19(5):595-602. PMID: 23603814.
      Citations: 58     Fields:    Translation:AnimalsCells
    15. Hu H, Brittain GC, Chang JH, Puebla-Osorio N, Jin J, Zal A, Xiao Y, Cheng X, Chang M, Fu YX, Zal T, Zhu C, Sun SC. OTUD7B controls non-canonical NF-?B activation through deubiquitination of TRAF3. Nature. 2013 Feb 21; 494(7437):371-4. PMID: 23334419.
      Citations: 72     Fields:    Translation:HumansAnimalsCells
    16. Jin J, Xiao Y, Chang JH, Yu J, Hu H, Starr R, Brittain GC, Chang M, Cheng X, Sun SC. The kinase TBK1 controls IgA class switching by negatively regulating noncanonical NF-?B signaling. Nat Immunol. 2012 Nov; 13(11):1101-9. PMID: 23023393.
      Citations: 41     Fields:    Translation:AnimalsCells
    17. Wang Q, Li SH, Wang H, Xiao Y, Sahin O, Brady SW, Li P, Ge H, Jaffee EM, Muller WJ, Hortobagyi GN, Yu D. Concomitant targeting of tumor cells and induction of T-cell response synergizes to effectively inhibit trastuzumab-resistant breast cancer. Cancer Res. 2012 Sep 01; 72(17):4417-28. PMID: 22773664.
      Citations: 13     Fields:    Translation:HumansAnimalsCells
    18. Chang JH, Xiao Y, Hu H, Jin J, Yu J, Zhou X, Wu X, Johnson HM, Akira S, Pasparakis M, Cheng X, Sun SC. Ubc13 maintains the suppressive function of regulatory T cells and prevents their conversion into effector-like T cells. Nat Immunol. 2012 May; 13(5):481-90. PMID: 22484734.
      Citations: 51     Fields:    Translation:AnimalsCells
    19. Ye Y, Xiao Y, Wang W, Gao JX, Yearsley K, Yan Q, Barsky SH. Singular v dual inhibition of SNF2L and its isoform, SNF2LT, have similar effects on DNA damage but opposite effects on the DNA damage response, cancer cell growth arrest and apoptosis. Oncotarget. 2012 Apr; 3(4):475-89. PMID: 22577152.
      Citations: 3     Fields:    Translation:HumansCells
    20. Chang M, Jin W, Chang JH, Xiao Y, Brittain GC, Yu J, Zhou X, Wang YH, Cheng X, Li P, Rabinovich BA, Hwu P, Sun SC. The ubiquitin ligase Peli1 negatively regulates T cell activation and prevents autoimmunity. Nat Immunol. 2011 Aug 28; 12(10):1002-9. PMID: 21874024.
      Citations: 66     Fields:    Translation:AnimalsCells
    21. Xiao Y, Ye Y, Zou X, Jones S, Yearsley K, Shetuni B, Tellez J, Barsky SH. The lymphovascular embolus of inflammatory breast cancer exhibits a Notch 3 addiction. Oncogene. 2011 Jan 20; 30(3):287-300. PMID: 20838375.
      Citations: 17     Fields:    Translation:HumansCells
    22. Mahooti S, Porter K, Alpaugh ML, Ye Y, Xiao Y, Jones S, Tellez JD, Barsky SH. Breast carcinomatous tumoral emboli can result from encircling lymphovasculogenesis rather than lymphovascular invasion. Oncotarget. 2010 Jun; 1(2):131-47. PMID: 21297224.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    23. Liu JQ, Joshi PS, Wang C, El-Omrani HY, Xiao Y, Liu X, Hagan JP, Liu CG, Wu LC, Bai XF. Targeting activation-induced cytidine deaminase overcomes tumor evasion of immunotherapy by CTLs. J Immunol. 2010 May 15; 184(10):5435-43. PMID: 20404277.
      Citations: 6     Fields:    Translation:AnimalsCells
    24. Ye Y, Xiao Y, Wang W, Yearsley K, Gao JX, Shetuni B, Barsky SH. ERalpha signaling through slug regulates E-cadherin and EMT. Oncogene. 2010 Mar 11; 29(10):1451-62. PMID: 20101232.
      Citations: 63     Fields:    Translation:HumansCells
    25. Charafe-Jauffret E, Ginestier C, Iovino F, Tarpin C, Diebel M, Esterni B, Houvenaeghel G, Extra JM, Bertucci F, Jacquemier J, Xerri L, Dontu G, Stassi G, Xiao Y, Barsky SH, Birnbaum D, Viens P, Wicha MS. Aldehyde dehydrogenase 1-positive cancer stem cells mediate metastasis and poor clinical outcome in inflammatory breast cancer. Clin Cancer Res. 2010 Jan 01; 16(1):45-55. PMID: 20028757.
      Citations: 290     Fields:    Translation:HumansAnimalsCells
    26. Ye Y, Xiao Y, Wang W, Wang Q, Yearsley K, Wani AA, Yan Q, Gao JX, Shetuni BS, Barsky SH. Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death. Mol Cancer Res. 2009 Dec; 7(12):1984-99. PMID: 19996304.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    27. Ye Y, Xiao Y, Wang W, Yearsley K, Gao JX, Barsky SH. ERalpha suppresses slug expression directly by transcriptional repression. Biochem J. 2008 Dec 01; 416(2):179-87. PMID: 18588516.
      Citations: 23     Fields:    Translation:HumansCells
    28. Xiao Y, Ye Y, Yearsley K, Jones S, Barsky SH. The lymphovascular embolus of inflammatory breast cancer expresses a stem cell-like phenotype. Am J Pathol. 2008 Aug; 173(2):561-74. PMID: 18599608.
      Citations: 40     Fields:    Translation:HumansAnimalsCells
    29. Piwil2 expressed in various stages of cervical neoplasia is a potential complementary marker for p16ink4a. American Journal of Translational Research. 2:156-169.
    30. Upregulation of lactate dehydrogenase a by 14-3-3ζ leads to increased glycolysis critical for breast cancer initiation and progression. Oncotarget. 7:35270-35283.
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