InstitutionMD Anderson
DepartmentPulmonary Medicine
Address2121 Holcombe Blvd
Houston TX 77030-4244
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gonzalez-Delgado R, Mu?oz NM, Carlos-Alcalde W, Cho MS, Lee H, Jin J, Serpas V, Gorlova O, Sheth RA, Afshar-Kharghan V. Role of circulating mitochondria in venous thrombosis in glioblastoma. J Thromb Haemost. 2023 08; 21(8):2202-2212. PMID: 37178770.
      Citations: 1     Fields:    Translation:Animals
    2. Zhang Z, Hong W, Wu Q, Tsavachidis S, Li JR, Amos CI, Cheng C, Sartain SE, Afshar-Kharghan V, Dong JF, Bhatraju P, Martin PJ, Makar RS, Bendapudi PK, Li A. Pathway-driven rare germline variants associated with transplant-associated thrombotic microangiopathy (TA-TMA). Thromb Res. 2023 05; 225:39-46. PMID: 36948020; PMCID: PMC10147584.
      Citations:    Fields:    Translation:HumansCells
    3. Kumar B, Afshar-Kharghan V, Mendt M, Sackstein R, Tanner MR, Popat U, Ramdial J, Daher M, Jimenez J, Basar R, Melo Garcia L, Shanley M, Kaplan M, Wan X, Nandivada V, Reyes Silva F, Woods V, Gilbert A, Gonzalez-Delgado R, Acharya S, Lin P, Rafei H, Banerjee PP, Shpall EJ. Engineered cord blood megakaryocytes evade killing by allogeneic T-cells for refractory thrombocytopenia. Front Immunol. 2022; 13:1018047. PMID: 36203567; PMCID: PMC9530569.
      Citations:    Fields:    Translation:AnimalsCells
    4. Qiao W, Young E, Feng C, Liu S, Jin J, Noor L, Rojas Hernandez CM, Borthakur G, Gorlova O, Afshar-Kharghan V. Association between abnormal lipid profile and inflammation and progression of myelodysplastic syndrome to acute leukemia. Exp Hematol Oncol. 2022 09 16; 11(1):58. PMID: 36114519; PMCID: PMC9479397.
    5. Corvigno S, Johnson AM, Wong KK, Cho MS, Afshar-Kharghan V, Menter DG, Sood AK. Novel Markers for Liquid Biopsies in Cancer Management: Circulating Platelets and Extracellular Vesicles. Mol Cancer Ther. 2022 07 05; 21(7):1067-1075. PMID: 35545008; PMCID: PMC10314793.
      Citations:    Fields:    Translation:HumansCells
    6. Cho MS, Lee H, Gonzalez-Delgado R, Li D, Sasano T, Carlos-Alcalde W, Ma Q, Liu J, Sood AK, Afshar-Kharghan V. Platelets Increase the Expression of PD-L1 in Ovarian Cancer. Cancers (Basel). 2022 May 19; 14(10). PMID: 35626102; PMCID: PMC9139585.
      Citations: 1     
    7. Yang M, Houck KL, Dong X, Hernandez M, Wang Y, Nathan SS, Wu X, Afshar-Kharghan V, Fu X, Cruz MA, Zhang J, Nascimbene A, Dong JF. Hyperadhesive von Willebrand Factor Promotes Extracellular Vesicle-Induced Angiogenesis: Implication for LVAD-Induced Bleeding. JACC Basic Transl Sci. 2022 Mar; 7(3):247-261. PMID: 35411318; PMCID: PMC8993768.
    8. Glassman D, Bateman NW, Lee S, Zhao L, Yao J, Tan Y, Ivan C, Rangel KM, Zhang J, Conrads KA, Hood BL, Abulez T, Futreal PA, Fleming ND, Afshar-Kharghan V, Maxwell GL, Conrads TP, Chen K, Sood AK. Molecular Correlates of Venous Thromboembolism (VTE) in Ovarian Cancer. Cancers (Basel). 2022 Mar 15; 14(6). PMID: 35326647; PMCID: PMC8946269.
    9. Menter DG, Afshar-Kharghan V, Shen JP, Martch SL, Maitra A, Kopetz S, Honn KV, Sood AK. Of vascular defense, hemostasis, cancer, and platelet biology: an evolutionary perspective. Cancer Metastasis Rev. 2022 03; 41(1):147-172. PMID: 35022962; PMCID: PMC8754476.
      Citations:    Fields:    Translation:HumansAnimalsCells
    10. Sasano T, Gonzalez-Delgado R, Carlos-Alcade W, Cho MS, Sheth RA, Sood AK, Afshar-Kharghan V, Mu?oz NM. Podoplanin promotes tumor growth, platelet aggregation, and venous thrombosis in murine models of ovarian cancer. J Thromb Haemost. 2022 01; 20(1):104-114. PMID: 34608736; PMCID: PMC8712373.
      Citations: 1     Fields:    Translation:AnimalsCells
    11. Saha B, Mathur T, Tronolone JJ, Chokshi M, Lokhande GK, Selahi A, Gaharwar AK, Afshar-Kharghan V, Sood AK, Bao G, Jain A. Human tumor microenvironment chip evaluates the consequences of platelet extravasation and combinatorial antitumor-antiplatelet therapy in ovarian cancer. Sci Adv. 2021 07; 7(30). PMID: 34290095; PMCID: PMC8294767.
      Citations: 5     Fields:    Translation:HumansCells
    12. Kanikarla Marie P, Fowlkes NW, Afshar-Kharghan V, Martch SL, Sorokin A, Shen JP, Morris VK, Dasari A, You N, Sood AK, Overman MJ, Kopetz S, Menter DG. The Provocative Roles of Platelets in Liver Disease and Cancer. Front Oncol. 2021; 11:643815. PMID: 34367949; PMCID: PMC8335590.
    13. Afshar-Kharghan V. Losing control to bad relatives. Blood. 2021 06 24; 137(25):3462-3463. PMID: 34165547; PMCID: PMC8225919.
      Citations:    Fields:    
    14. Cho MS, Li J, Gonzalez-Delgado R, Lee H, Vasquez M, He T, He Y, Liu K, Sasano T, Sood AK, Wong STC, Afshar-Kharghan V, N?rnberg B. The effect of platelet G proteins on platelet extravasation and tumor growth in the murine model of ovarian cancer. Blood Adv. 2021 04 13; 5(7):1947-1951. PMID: 33821990; PMCID: PMC8045495.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    15. Oncul S, Afshar-Kharghan V. The interaction between the complement system and hemostatic factors. Curr Opin Hematol. 2020 09; 27(5):341-352. PMID: 32701617; PMCID: PMC7773221.
      Citations: 4     Fields:    Translation:Humans
    16. Saha B, Mathur T, Handley KF, Hu W, Afshar-Kharghan V, Sood AK, Jain A. OvCa-Chip microsystem recreates vascular endothelium-mediated platelet extravasation in ovarian cancer. Blood Adv. 2020 07 28; 4(14):3329-3342. PMID: 32717032; PMCID: PMC7391144.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    17. Afshar-Kharghan V. APC ameliorates pulmonary complications in cGVHD. Blood. 2019 08 29; 134(9):724-725. PMID: 31467078; PMCID: PMC6716073.
      Citations:    Fields:    Translation:HumansCells
    18. Ma Q, Li D, Vasquez HG, You MJ, Afshar-Kharghan V. Kidney Injury in Murine Models of Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2019 10; 25(10):1920-1924. PMID: 31271886; PMCID: PMC6790281.
      Citations: 2     Fields:    Translation:HumansAnimals
    19. Haemmerle M, Stone RL, Menter DG, Afshar-Kharghan V, Sood AK. The Platelet Lifeline to Cancer: Challenges and Opportunities. Cancer Cell. 2018 06 11; 33(6):965-983. PMID: 29657130; PMCID: PMC5997503.
      Citations: 144     Fields:    Translation:HumansAnimalsCells
    20. Haemmerle M, Taylor ML, Gutschner T, Pradeep S, Cho MS, Sheng J, Lyons YM, Nagaraja AS, Dood RL, Wen Y, Mangala LS, Hansen JM, Rupaimoole R, Gharpure KM, Rodriguez-Aguayo C, Yim SY, Lee JS, Ivan C, Hu W, Lopez-Berestein G, Wong ST, Karlan BY, Levine DA, Liu J, Afshar-Kharghan V, Sood AK. Platelets reduce anoikis and promote metastasis by activating YAP1 signaling. Nat Commun. 2017 08 21; 8(1):310. PMID: 28827520; PMCID: PMC5566477.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    21. Cho MS, Noh K, Haemmerle M, Li D, Park H, Hu Q, Hisamatsu T, Mitamura T, Mak SLC, Kunapuli S, Ma Q, Sood AK, Afshar-Kharghan V. Role of ADP receptors on platelets in the growth of ovarian cancer. Blood. 2017 09 07; 130(10):1235-1242. PMID: 28679740; PMCID: PMC5606004.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    22. Hu Q, Hisamatsu T, Haemmerle M, Cho MS, Pradeep S, Rupaimoole R, Rodriguez-Aguayo C, Lopez-Berestein G, Wong STC, Sood AK, Afshar-Kharghan V. Role of Platelet-Derived Tgf?1 in the Progression of Ovarian Cancer. Clin Cancer Res. 2017 Sep 15; 23(18):5611-5621. PMID: 28611202; PMCID: PMC5600833.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    23. Afshar-Kharghan V. Complement and clot. Blood. 2017 04 20; 129(16):2214-2215. PMID: 28428238; PMCID: PMC5399487.
      Citations: 8     Fields:    Translation:Humans
    24. Afshar-Kharghan V. The role of the complement system in cancer. J Clin Invest. 2017 Mar 01; 127(3):780-789. PMID: 28248200; PMCID: PMC5330758.
      Citations: 154     Fields:    Translation:HumansAnimalsCells
    25. Afshar-Kharghan V. Atypical hemolytic uremic syndrome. Hematology Am Soc Hematol Educ Program. 2016 Dec 02; 2016(1):217-225. PMID: 27913483; PMCID: PMC6142509.
      Citations: 14     Fields:    Translation:Humans
    26. Hu Q, Cho MS, Thiagarajan P, Aung FM, Sood AK, Afshar-Kharghan V. A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets. Platelets. 2017 Jan; 28(1):99-102. PMID: 27534811; PMCID: PMC5310196.
      Citations: 5     Fields:    Translation:HumansCells
    27. Hu Q, Wang M, Cho MS, Wang C, Nick AM, Thiagarajan P, Aung FM, Han X, Sood AK, Afshar-Kharghan V. Lipid profile of platelets and platelet-derived microparticles in ovarian cancer. BBA Clin. 2016 Dec; 6:76-81. PMID: 27453821; PMCID: PMC4941562.
      Citations: 11     
    28. Feng S, Kroll MH, Nick AM, Sood AK, Afshar-Kharghan V. Platelets are not hyperreactive in patients with ovarian cancer. Platelets. 2016 Nov; 27(7):716-718. PMID: 27185008; PMCID: PMC5184822.
      Citations: 6     Fields:    Translation:HumansCells
    29. Haemmerle M, Bottsford-Miller J, Pradeep S, Taylor ML, Choi HJ, Hansen JM, Dalton HJ, Stone RL, Cho MS, Nick AM, Nagaraja AS, Gutschner T, Gharpure KM, Mangala LS, Rupaimoole R, Han HD, Zand B, Armaiz-Pena GN, Wu SY, Pecot CV, Burns AR, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest. 2016 05 02; 126(5):1885-96. PMID: 27064283; PMCID: PMC4855933.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    30. Cho MS, Rupaimoole R, Choi HJ, Noh K, Chen J, Hu Q, Sood AK, Afshar-Kharghan V. Complement Component 3 Is Regulated by TWIST1 and Mediates Epithelial-Mesenchymal Transition. J Immunol. 2016 Feb 01; 196(3):1412-8. PMID: 26718342; PMCID: PMC4724537.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    31. Wang R, Stone RL, Kaelber JT, Rochat RH, Nick AM, Vijayan KV, Afshar-Kharghan V, Schmid MF, Dong JF, Sood AK, Chiu W. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proc Natl Acad Sci U S A. 2015 Nov 17; 112(46):14266-71. PMID: 26578771; PMCID: PMC4655568.
      Citations: 25     Fields:    Translation:HumansCellsCTClinical Trials
    32. Ciurea SO, Thall PF, Barnes TH, Kongtim P, Carmazzi Y, Yap DY, Popat U, Rondon G, Lichtiger B, Aung F, Afshar-Kharghan V, Ma Q, Champlin RE, Cao K, Milton DR, L?pez AA, Fern?ndez-Vi?a M. Complement-Binding Donor-Specific Anti-HLA Antibodies and Risk of Primary Graft Failure in Hematopoietic Stem Cell Transplantation. Biol Blood Marrow Transplant. 2015 Aug; 21(8):1392-8. PMID: 25985919; PMCID: PMC4506716.
      Citations: 37     Fields:    Translation:Humans
    33. Pemmaraju N, Sasaki K, Johnson D, Daver N, Afshar-Kharghan V, Chen M, Ahmed S, Colen RR, Kwon M, Huh Y, Borthakur G. Successful Treatment of Intracranial Hemorrhage with Recombinant Activated Factor VII in a Patient with Newly Diagnosed Acute Myeloid Leukemia: A Case Report and Review of the Literature. Front Oncol. 2015; 5:29. PMID: 25717439; PMCID: PMC4324079.
      Citations: 1     
    34. Bottsford-Miller J, Choi HJ, Dalton HJ, Stone RL, Cho MS, Haemmerle M, Nick AM, Pradeep S, Zand B, Previs RA, Pecot CV, Crane EK, Hu W, Lutgendorf SK, Afshar-Kharghan V, Sood AK. Differential platelet levels affect response to taxane-based therapy in ovarian cancer. Clin Cancer Res. 2015 Feb 01; 21(3):602-10. PMID: 25473001; PMCID: PMC4315757.
      Citations: 42     Fields:    Translation:HumansAnimalsCells
    35. Feng S, Liang X, Kroll MH, Chung DW, Afshar-Kharghan V. von Willebrand factor is a cofactor in complement regulation. Blood. 2015 Feb 05; 125(6):1034-7. PMID: 25395424; PMCID: PMC4319234.
      Citations: 25     Fields:    Translation:HumansCells
    36. Afshar-Kharghan V. COMPLEMENTing the diagnosis of aHUS. Blood. 2014 Sep 11; 124(11):1699-700. PMID: 25214194; PMCID: PMC4162100.
      Citations: 1     Fields:    Translation:Humans
    37. Wu W, Merriman K, Nabaah A, Seval N, Afshar-Kharghan V, Yeung SC. Heparin-induced thrombocytopenia among patients of a comprehensive cancer center. SAGE Open Med Case Rep. 2014; 2:2050313X14533945. PMID: 27489647; PMCID: PMC4857356.
      Citations: 3     
    38. Lin RJ, Afshar-Kharghan V, Schafer AI. Paraneoplastic thrombocytosis: the secrets of tumor self-promotion. Blood. 2014 Jul 10; 124(2):184-7. PMID: 24868077; PMCID: PMC4093679.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    39. Ma Q, Li D, Patenia R, Tsai KY, Xydes-Smith M, Alousi AM, Champlin RE, Carre?o R, Sale GE, Afshar-Kharghan V. Complement component C3 mediates Th1/Th17 polarization in human T-cell activation and cutaneous GVHD. Bone Marrow Transplant. 2014 Jul; 49(7):972-6. PMID: 24777193; PMCID: PMC4410869.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    40. Davis AN, Afshar-Kharghan V, Sood AK. Platelet effects on ovarian cancer. Semin Oncol. 2014 Jun; 41(3):378-84. PMID: 25023353; PMCID: PMC4100073.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    41. Cho MS, Vasquez HG, Rodriguez-Aguayo C, Baggerly K, Lopez-Berestein G, Afshar-Kharghan V, Rupaimoole R, Pradeep S, Wu S, Zand B, Han HD, Bottsford-Miller J, Huang J, Miyake T, Choi HJ, Dalton HJ, Ivan C, Sood AK. Autocrine effects of tumor-derived complement. Cell Rep. 2014 Mar 27; 6(6):1085-1095. PMID: 24613353; PMCID: PMC4084868.
      Citations: 89     Fields:    Translation:HumansAnimalsCells
    42. Nolasco L, Nolasco J, Feng S, Afshar-Kharghan V, Moake J. Human complement factor H is a reductase for large soluble von Willebrand factor multimers--brief report. Arterioscler Thromb Vasc Biol. 2013 Nov; 33(11):2524-8. PMID: 24008159.
      Citations: 16     Fields:    Translation:HumansCells
    43. Feng S, Liang X, Cruz MA, Vu H, Zhou Z, Pemmaraju N, Dong JF, Kroll MH, Afshar-Kharghan V. The interaction between factor H and Von Willebrand factor. PLoS One. 2013; 8(8):e73715. PMID: 23991205; PMCID: PMC3753316.
      Citations: 18     Fields:    Translation:HumansCells
    44. Feng S, Eyler SJ, Zhang Y, Maga T, Nester CM, Kroll MH, Smith RJ, Afshar-Kharghan V. Partial ADAMTS13 deficiency in atypical hemolytic uremic syndrome. Blood. 2013 Aug 22; 122(8):1487-93. PMID: 23847193; PMCID: PMC3750341.
      Citations: 35     Fields:    Translation:Humans
    45. Thiagarajan P, Afshar-Kharghan V. Platelet transfusion therapy. Hematol Oncol Clin North Am. 2013 Jun; 27(3):629-43. PMID: 23714315.
      Citations: 6     Fields:    Translation:HumansCells
    46. Feng S, Kroll MH, Nolasco L, Moake J, Afshar-Kharghan V. Complement activation in thrombotic microangiopathies. Br J Haematol. 2013 Feb; 160(3):404-6. PMID: 23116127; PMCID: PMC3758746.
      Citations: 6     Fields:    Translation:Humans
    47. Cho MS, Bottsford-Miller J, Vasquez HG, Stone R, Zand B, Kroll MH, Sood AK, Afshar-Kharghan V. Platelets increase the proliferation of ovarian cancer cells. Blood. 2012 Dec 06; 120(24):4869-72. PMID: 22966171; PMCID: PMC3520623.
      Citations: 100     Fields:    Translation:HumansAnimalsCells
    48. Kroll MH, Afshar-Kharghan V. Platelets in pulmonary vascular physiology and pathology. Pulm Circ. 2012 Jul; 2(3):291-308. PMID: 23130099; PMCID: PMC3487299.
      Citations: 11     
    49. Ma Q, Li D, Nurieva R, Patenia R, Bassett R, Cao W, Alekseev AM, He H, Molldrem JJ, Kroll MH, Champlin RE, Sale GE, Afshar-Kharghan V. Reduced graft-versus-host disease in C3-deficient mice is associated with decreased donor Th1/Th17 differentiation. Biol Blood Marrow Transplant. 2012 Aug; 18(8):1174-81. PMID: 22664751; PMCID: PMC3437318.
      Citations: 12     Fields:    Translation:AnimalsCells
    50. Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, Rupairmoole R, Armaiz-Pena GN, Pecot CV, Coward J, Deavers MT, Vasquez HG, Urbauer D, Landen CN, Hu W, Gershenson H, Matsuo K, Shahzad MM, King ER, Tekedereli I, Ozpolat B, Ahn EH, Bond VK, Wang R, Drew AF, Gushiken F, Lamkin D, Collins K, DeGeest K, Lutgendorf SK, Chiu W, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. Paraneoplastic thrombocytosis in ovarian cancer. N Engl J Med. 2012 Feb 16; 366(7):610-8. PMID: 22335738; PMCID: PMC3296780.
      Citations: 316     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    51. Zalpour A, Kroll MH, Afshar-Kharghan V, Yusuf SW, Escalante C. Role of factor xa inhibitors in cancer-associated thrombosis: any new data? Adv Hematol. 2011; 2011:196135. PMID: 22013445; PMCID: PMC3195274.
      Citations: 3     
    52. Divakaran V, Mehta S, Yao D, Hassan S, Simpson S, Wiegerinck E, Swinkels DW, Mann DL, Afshar-Kharghan V. Hepcidin in anemia of chronic heart failure. Am J Hematol. 2011 Jan; 86(1):107-9. PMID: 21080339; PMCID: PMC3076004.
      Citations: 8     Fields:    Translation:Humans
    53. Hanzelka KM, Zalpour A, Afshar-Kharghan V, Fitousis K, Anderlini P, Yeung SC. Severe thrombosis and acute thrombocytopenia in a cancer patient. Am J Hematol. 2010 Nov; 85(11):887-90. PMID: 20721891.
      Citations: 1     Fields:    Translation:Humans
    54. Seo N, Russell BH, Rivera JJ, Liang X, Xu X, Afshar-Kharghan V, H??k M. An engineered alpha1 integrin-binding collagenous sequence. J Biol Chem. 2010 Oct 01; 285(40):31046-54. PMID: 20675378; PMCID: PMC2945595.
      Citations: 27     Fields:    Translation:HumansCells
    55. Gushiken FC, Han H, Li J, Rumbaut RE, Afshar-Kharghan V. Abnormal platelet function in C3-deficient mice. J Thromb Haemost. 2009 May; 7(5):865-70. PMID: 19291167; PMCID: PMC2867673.
      Citations: 22     Fields:    Translation:AnimalsCells
    56. Kulkarni PA, Afshar-Kharghan V. Anticomplement therapy. Biologics. 2008 Dec; 2(4):671-85. PMID: 19707448; PMCID: PMC2727911.
      Citations: 3     
    57. Mnjoyan Z, Li J, Afshar-Kharghan V. Factor H binds to platelet integrin alphaIIbbeta3. Platelets. 2008 Nov; 19(7):512-9. PMID: 18979363.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    58. Afshar-Kharghan V. Unleashed platelets in aHUS. Blood. 2008 Jun 01; 111(11):5266. PMID: 18502839.
      Citations: 3     Fields:    
    59. Jelinek J, Li J, Mnjoyan Z, Issa JP, Prchal JT, Afshar-Kharghan V. Epigenetic control of PRV-1 expression on neutrophils. Exp Hematol. 2007 Nov; 35(11):1677-83. PMID: 17976520.
      Citations: 5     Fields:    Translation:HumansCells
    60. Diz-Kucukkaya R, Inanc M, Afshar-Kharghan V, Zhang QE, Pekcelen Y, L?pez JA. P-selectin glycoprotein ligand-1 VNTR polymorphisms and risk of thrombosis in the antiphospholipid syndrome. Ann Rheum Dis. 2007 Oct; 66(10):1378-80. PMID: 17545190; PMCID: PMC1994305.
      Citations: 6     Fields:    Translation:HumansCells
    61. Luo SZ, Mo X, Afshar-Kharghan V, Srinivasan S, Li R, L?pez JA. Glycoprotein Ibalpha forms disulfide bonds with 2 glycoprotein Ibbeta subunits in the resting platelet. Blood. 2007 Jan 15; 109(2):603-9. PMID: 17008541; PMCID: PMC1785083.
      Citations: 53     Fields:    Translation:HumansAnimalsCells
    62. Mnjoyan Z, Yoon D, Li J, Afshar-Kharghan V, Delhommeau F. The effect of the JAK2 V617F mutation on PRV-1 expression. Haematologica. 2006 Mar; 91(3):411-2. PMID: 16503546.
      Citations: 1     Fields:    Translation:HumansCells
    63. Afshar-Kharghan V, Thiagarajan P. Leukocyte adhesion and thrombosis. Curr Opin Hematol. 2006 Jan; 13(1):34-9. PMID: 16319685.
      Citations: 29     Fields:    Translation:HumansAnimalsCells
    64. Del Conde I, Zhang H, Afshar-Kharghan V, Cr?z MA, L?pez JA. Platelet activation leads to activation and propagation of the complement system. J Exp Med. 2005 Mar 21; 201(6):871-9. PMID: 15781579; PMCID: PMC2213112.
      Citations: 137     Fields:    Translation:HumansAnimalsCells
    65. Mnjoyan Z, Li J, Afshar-Kharghan V. Expression of polycythemia rubra vera-1 decreases the dependency of cells on growth factors for proliferation. Haematologica. 2005 Mar; 90(3):405-6. PMID: 15749675.
      Citations: 1     Fields:    Translation:AnimalsCells
    66. Afshar-Kharghan V, Gray LA, Padilla A, Borthakur G, Roberts SC, Pruthi RK, Tefferi A, L?pez JA. Hemostatic gene polymorphisms and the prevalence of thrombotic complications in polycythemia vera and essential thrombocythemia. Blood Coagul Fibrinolysis. 2004 Jan; 15(1):21-4. PMID: 15166939.
      Citations: 3     Fields:    Translation:Humans
    67. Afshar-Kharghan V, Matijevic-Aleksic N, Ahn C, Boerwinkle E, Wu KK, L?pez JA. The variable number of tandem repeat polymorphism of platelet glycoprotein Ibalpha and risk of coronary heart disease. Blood. 2004 Feb 01; 103(3):963-5. PMID: 14592833.
      Citations: 8     Fields:    Translation:HumansCells
    68. Baker RI, Eikelboom J, Lofthouse E, Staples N, Afshar-Kharghan V, Shen Y, Berndt MC, Hankey G, L?pez JA. Platelet glycoprotein Ibalpha Kozak polymorphism is associated with an increased risk of ischemic stroke. Blood. 2001 Jul 01; 98(1):36-40. PMID: 11418460.
      Citations: 15     Fields:    Translation:HumansCells
    69. Afshar-Kharghan V, Ludwig EH, Marian AJ, Diz-K???kkaya R, L?pez JA. Human polymorphism of P-selectin glycoprotein ligand 1 attributable to variable numbers of tandem decameric repeats in the mucinlike region. Blood. 2001 May 15; 97(10):3306-7. PMID: 11342464.
      Citations: 15     Fields:    Translation:HumansCells
    70. Afshar-Kharghan V, Craig FE, L?pez JA. Bernard-Soulier syndrome in a patient doubly heterozygous for two frameshift mutations in the glycoprotein ib alpha gene. Br J Haematol. 2000 Sep; 110(4):919-24. PMID: 11054083.
      Citations: 3     Fields:    Translation:HumansCells
    71. Afshar-Kharghan V, Gineys G, Schade AJ, Sun L, Li CQ, McIntire LV, Dong JF, L?pez JA. Necessity of conserved asparagine residues in the leucine-rich repeats of platelet glycoprotein Ib alpha for the proper conformation and function of the ligand-binding region. Biochemistry. 2000 Mar 28; 39(12):3384-91. PMID: 10727232.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    72. Sachs UJ, Kiefel V, Afshar-Kharghan V, Kroll H, Santoso S, B?hringer M. Single amino acid substitution in human platelet glycoprotein Ibbeta is responsible for the formation of the platelet-specific alloantigen Iy(a). Blood. 2000 Mar 01; 95(5):1849-55. PMID: 10688847.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    73. Afshar-Kharghan V, Li CQ, Khoshnevis-Asl M, L?pez JA. Kozak sequence polymorphism of the glycoprotein (GP) Ibalpha gene is a major determinant of the plasma membrane levels of the platelet GP Ib-IX-V complex. Blood. 1999 Jul 01; 94(1):186-91. PMID: 10381512.
      Citations: 21     Fields:    Translation:HumansCells
    74. Andrews RK, Afshar-Kharghan V, Berndt MC, L?pez JA. Bernard-Soulier syndrome. Blood. 1998 Jun 15; 91(12):4397-418. PMID: 9616133.
      Citations: 104     Fields:    Translation:HumansCells
    75. Dong JF, Li CQ, Sae-Tung G, Hyun W, Afshar-Kharghan V, L?pez JA. The cytoplasmic domain of glycoprotein (GP) Ibalpha constrains the lateral diffusion of the GP Ib-IX complex and modulates von Willebrand factor binding. Biochemistry. 1997 Oct 14; 36(41):12421-7. PMID: 9376345.
      Citations: 15     Fields:    Translation:HumansCells
    76. Afshar-Kharghan V, L?pez JA. Bernard-Soulier syndrome caused by a dinucleotide deletion and reading frameshift in the region encoding the glycoprotein Ib alpha transmembrane domain. Blood. 1997 Oct 01; 90(7):2634-43. PMID: 9326230.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    77. A small amount of cyclooxygenase 2 (COX2) is constitutively expressed in platelets. Platelets. 1-4.
    78. Successful treatment of intracranial hemorrhage with recombinant activated factor VII in a patient with newly diagnosed acute myeloid leukemia. Frontiers in Oncology. 5.
    79. Electron cryotomography reveals ultrastructure alterations in platelets from patients with ovarian cancer. Proceedings of the National Academy of Sciences of the United States of America. 112:14266-14271.
    80. Complement component 3 is regulated by TWIST1 and mediates epithelial-mesenchymal transition. Journal of Immunology. 196:1412-1418.
    81. The authors reply. New England Journal of Medicine. 366:1840.
    82. Complement-Binding Donor-Specific Anti-HLA Antibodies and Risk of Primary Graft Failure in Hematopoietic Stem Cell Transplantation. Biology of Blood and Marrow Transplantation. 21:1392-1398.
    83. Platelets are not hyperreactive in patients with ovarian cancer. Platelets. 1-3.
    84. Lipid profile of platelets and platelet-derived microparticles in ovarian cancer. BBA Clinical. 6:76-81.
    85. Platelet polymorphisms. 281-307.
    86. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. Journal of Clinical Investigation. 126:1885-1896.
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