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LIKUN LI

TitleAssistant Professor
InstitutionMD Anderson
DepartmentGenitourinary Medical Oncology
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Thompson TC, Li L. New targets for resistant prostate cancer. Oncotarget. 2014 Oct 15; 5(19):8816-7. PMID: 25301740.
      View in: PubMed
    2. Li L, Chang W, Yang G, Ren C, Park S, Karantanos T, Karanika S, Wang J, Yin J, Shah PK, Takahiro H, Dobashi M, Zhang W, Efstathiou E, Maity SN, Aparicio AM, Li Ning Tapia EM, Troncoso P, Broom B, Xiao L, Lee HS, Lee JS, Corn PG, Navone N, Thompson TC. Targeting poly(ADP-ribose) polymerase and the c-Myb-regulated DNA damage response pathway in castration-resistant prostate cancer. Sci Signal. 2014 May 20; 7(326):ra47. PMID: 24847116.
      View in: PubMed
    3. Li L, Yang G, Ren C, Tanimoto R, Hirayama T, Wang J, Hawke D, Kim SM, Lee JS, Goltsov AA, Park S, Ittmann MM, Troncoso P, Thompson TC. Glioma pathogenesis-related protein 1 induces prostate cancer cell death through Hsc70-mediated suppression of AURKA and TPX2. Mol Oncol. 2013 Jun; 7(3):484-96. PMID: 23333597.
      View in: PubMed
    4. Li L, Ren C, Yang G, Fattah EA, Goltsov AA, Kim SM, Lee JS, Park S, Demayo FJ, Ittmann MM, Troncoso P, Thompson TC. GLIPR1 suppresses prostate cancer development through targeted oncoprotein destruction. Cancer Res. 2011 Dec 15; 71(24):7694-704. PMID: 22025562.
      View in: PubMed
    5. Li L, Ren C, Yang G, Goltsov AA, Tabata K, Thompson TC. Caveolin-1 promotes autoregulatory, Akt-mediated induction of cancer-promoting growth factors in prostate cancer cells. Mol Cancer Res. 2009 Nov; 7(11):1781-91. PMID: 19903767.
      View in: PubMed
    6. Thompson TC, Tahir SA, Li L, Watanabe M, Naruishi K, Yang G, Kadmon D, Logothetis CJ, Troncoso P, Ren C, Goltsov A, Park S. The role of caveolin-1 in prostate cancer: clinical implications. Prostate Cancer Prostatic Dis. 2010 Mar; 13(1):6-11. PMID: 19581923.
      View in: PubMed
    7. Li L, Abdel Fattah E, Cao G, Ren C, Yang G, Goltsov AA, Chinault AC, Cai WW, Timme TL, Thompson TC. Glioma pathogenesis-related protein 1 exerts tumor suppressor activities through proapoptotic reactive oxygen species-c-Jun-NH2 kinase signaling. Cancer Res. 2008 Jan 15; 68(2):434-43. PMID: 18199537.
      View in: PubMed
    8. Ren C, Ren CH, Li L, Goltsov AA, Thompson TC. Identification and characterization of RTVP1/GLIPR1-like genes, a novel p53 target gene cluster. Genomics. 2006 Aug; 88(2):163-72. PMID: 16714093.
      View in: PubMed
    9. Li L, Ittmann MM, Ayala G, Tsai MJ, Amato RJ, Wheeler TM, Miles BJ, Kadmon D, Thompson TC. The emerging role of the PI3-K-Akt pathway in prostate cancer progression. Prostate Cancer Prostatic Dis. 2005; 8(2):108-18. PMID: 15724144.
      View in: PubMed
    10. Bondos SE, Catanese DJ, Tan XX, Bicknell A, Li L, Matthews KS. Hox transcription factor ultrabithorax Ib physically and genetically interacts with disconnected interacting protein 1, a double-stranded RNA-binding protein. J Biol Chem. 2004 Jun 18; 279(25):26433-44. PMID: 15039447.
      View in: PubMed
    11. Ren C, Li L, Yang G, Timme TL, Goltsov A, Ren C, Ji X, Addai J, Luo H, Ittmann MM, Thompson TC. RTVP-1, a tumor suppressor inactivated by methylation in prostate cancer. Cancer Res. 2004 Feb 01; 64(3):969-76. PMID: 14871827.
      View in: PubMed
    12. Li L, Ren CH, Tahir SA, Ren C, Thompson TC. Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol. 2003 Dec; 23(24):9389-404. PMID: 14645548.
      View in: PubMed
    13. Mouraviev V, Li L, Tahir SA, Yang G, Timme TM, Goltsov A, Ren C, Satoh T, Wheeler TM, Ittmann MM, Miles BJ, Amato RJ, Kadmon D, Thompson TC. The role of caveolin-1 in androgen insensitive prostate cancer. J Urol. 2002 Oct; 168(4 Pt 1):1589-96. PMID: 12352463.
      View in: PubMed
    14. Ren C, Li L, Goltsov AA, Timme TL, Tahir SA, Wang J, Garza L, Chinault AC, Thompson TC. mRTVP-1, a novel p53 target gene with proapoptotic activities. Mol Cell Biol. 2002 May; 22(10):3345-57. PMID: 11971968.
      View in: PubMed
    15. Tan XX, Bondos S, Li L, Matthews KS. Transcription activation by ultrabithorax Ib protein requires a predicted alpha-helical region. Biochemistry. 2002 Feb 26; 41(8):2774-85. PMID: 11851425.
      View in: PubMed
    16. Li L, Yang G, Ebara S, Satoh T, Nasu Y, Timme TL, Ren C, Wang J, Tahir SA, Thompson TC. Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells. Cancer Res. 2001 Jun 01; 61(11):4386-92. PMID: 11389065.
      View in: PubMed
    17. Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, Li L, Goltsov A, Ittmann M, Morrisett JD, Thompson TC. Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen-insensitive prostate cancer. Cancer Res. 2001 May 15; 61(10):3882-5. PMID: 11358800.
      View in: PubMed
    18. Timme TL, Goltsov A, Tahir S, Li L, Wang J, Ren C, Johnston RN, Thompson TC. Caveolin-1 is regulated by c-myc and suppresses c-myc-induced apoptosis. Oncogene. 2000 Jul 06; 19(29):3256-65. PMID: 10918582.
      View in: PubMed
    19. Thompson TC, Timme TL, Li L, Goltsov A. Caveolin-1, a metastasis-related gene that promotes cell survival in prostate cancer. Apoptosis. 1999 Aug; 4(4):233-7. PMID: 14634273.
      View in: PubMed
    20. Nasu Y, Timme TL, Yang G, Bangma CH, Li L, Ren C, Park SH, DeLeon M, Wang J, Thompson TC. Suppression of caveolin expression induces androgen sensitivity in metastatic androgen-insensitive mouse prostate cancer cells. Nat Med. 1998 Sep; 4(9):1062-4. PMID: 9734401.
      View in: PubMed
    21. Li L, Matthews KS. Differences in water release with DNA binding by ultrabithorax and deformed homeodomains. Biochemistry. 1997 Jun 10; 36(23):7003-11. PMID: 9188697.
      View in: PubMed
    22. Li L, von Kessler D, Beachy PA, Matthews KS. pH-dependent enhancement of DNA binding by the ultrabithorax homeodomain. Biochemistry. 1996 Jul 30; 35(30):9832-9. PMID: 8703957.
      View in: PubMed
    23. Li L, Matthews KS. Characterization of mutants affecting the KRK sequence in the carboxyl-terminal domain of lac repressor. J Biol Chem. 1995 May 05; 270(18):10640-9. PMID: 7738001.
      View in: PubMed
    24. Molecular Cancer. 14.
    25. Caveolin-1. Expert Opinion on Therapeutic Targets. 3:337-346.
    26. DNA damage response and prostate cancer. Oncogene. 0.
    27. Caveolin-1 regulates hormone resistance through lipid synthesis, creating novel therapeutic opportunities for castration-resistant prostate cancer. Oncotarget. 7:46321-46334.
    28. β-Glucan synthesis in the cotton fiber. Plant Physiology. 101:1131-1142.
    29. β-Glucan synthesis in the cotton fiber. Plant Physiology. 101:1149-1156.
    30. β-Glucan synthesis in the cotton fiber. Plant Physiology. 101:1143-1148.
    31. Plant Physiology. 107:111-123.
    32. pH-dependent DNA binding by homeodomain from ultrabithorax protein. FASEB Journal. 10.
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