SAMUEL SHELBURNE

TitleAssociate Professor
InstitutionMD Anderson
DepartmentInfectious Diseases, Infection Control, and Employee Health
Address1901 East Road
Houston TX 77054-3005
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    R21AI177931     (SHELBURNE, SAMUEL A)Feb 1, 2024 - Dec 31, 2025
    NIH
    Delineation of mechanisms underlying response regulator activation in group A Streptococcus
    Role: Principal Investigator

    R21AI156202     (SHELBURNE, SAMUEL A)Jul 12, 2021 - Jun 30, 2023
    NIH
    Impact of regulatory cross-talk on the pathophysiology of emergent acapsular group A streptococcus
    Role: Principal Investigator

    R21AI151536     (SHELBURNE, SAMUEL A)Mar 17, 2021 - Feb 29, 2024
    NIH
    Role of ß-lactamase encoding gene amplification in the development of non-carbapenemase producing, carbapenem-resistant Enterobacteriaceae
    Role: Principal Investigator

    R21AI159059     (FLORES, ANTHONY RICHARD;SHELBURNE, SAMUEL A)Mar 8, 2021 - Feb 29, 2024
    NIH
    Defining novel mechanisms of clonal emergence in Group A Streptococcus
    Role: Principal Investigator

    P01AI152999     (ARIAS, CESAR AUGUSTO ;SAVIDGE, TOR ;SHELBURNE, SAMUEL A)Aug 1, 2020 - Jul 31, 2025
    NIH
    Dynamics of Colonization and Infection by Multidrug-resistant Pathogens in Immunocompromised and Critically Ill Patients (DYNAMITE)
    Role: Co-Principal Investigator

    R21AI142126     (SHELBURNE, SAMUEL A)Dec 6, 2018 - Nov 30, 2021
    NIH
    Impact of a novel emm-enn gene fusion event on epidemic behavior of group A streptococcus
    Role: Principal Investigator

    R21AI132920     (SHELBURNE, SAMUEL A)May 14, 2018 - Apr 30, 2021
    NIH
    Novel mechanisms of emergence of hypervirulent group A Streptococcus
    Role: Principal Investigator

    R01AI125292     (SHELBURNE, SAMUEL A)Jan 16, 2017 - Dec 31, 2021
    NIH
    Role of response regulator phosphorylation in group A streptococcal pathogenesis
    Role: Principal Investigator

    R01AI089891     (SHELBURNE, SAMUEL A)Jul 15, 2011 - Jun 30, 2017
    NIH
    Contribution of catabolite control protein A to group A streptococcal virulence
    Role: Principal Investigator

    K08AI064564     (SHELBURNE, SAMUEL A)Jul 1, 2006 - May 31, 2011
    NIH
    Analysis Of Group A Streptococcus-Saliva Interaction
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gerges B, Rosenblatt J, Truong YL, Jiang Y, Shelburne SA, Chaftari AM, Hachem R, Raad I. In vitro activity of cefepime/taniborbactam and comparator agents against Gram-negative bacterial bloodstream pathogens recovered from patients with cancer. JAC Antimicrob Resist. 2024 Apr; 6(2):dlae060. PMID: 38601790; PMCID: PMC11005172.
      Citations:    
    2. Torres HA, Mustafayev K, Nastoupil LJ, Shelburne SA. Severe reactivation of seronegative occult hepatitis B after chemotherapy for lymphoma. Lancet. 2024 Apr 06; 403(10434):1372-1373. PMID: 38582568.
      Citations:    
    3. Selvaraj Anand S, Wu CT, Bremer J, Bhatti M, Treangen TJ, Kalia A, Shelburne SA, Shropshire WC. Identification of a novel CG307 sub-clade in third-generation-cephalosporin-resistant Klebsiella pneumoniae causing invasive infections in the USA. Microb Genom. 2024 Feb; 10(2). PMID: 38407244; PMCID: PMC10926705.
      Citations:    Fields:    Translation:HumansCells
    4. Egge SL, Rizvi SA, Simar SR, Alcalde M, Martinez JRW, Hanson BM, Dinh AQ, Baptista RP, Tran TT, Shelburne SA, Munita JM, Arias CA, Hakki M, Miller WR. Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin. bioRxiv. 2024 Jan 31. PMID: 38352536; PMCID: PMC10862867.
      Citations:    
    5. Axell-House DB, Simar SR, Panesso D, Rincon S, Miller WR, Khan A, Pemberton OA, Valdez L, Nguyen AH, Hood KS, Rydell K, DeTranaltes AM, Jones MN, Atterstrom R, Reyes J, Sahasrabhojane PV, Suleyman G, Zervos M, Shelburne SA, Singh KV, Shamoo Y, Hanson BM, Tran TT, Arias CA. LiaX is a surrogate marker for cell envelope stress and daptomycin non-susceptibility in Enterococcus faecium. Antimicrob Agents Chemother. 2024 Mar 06; 68(3):e0106923. PMID: 38289081; PMCID: PMC10916372.
      Citations:    Fields:    Translation:HumansCells
    6. Kawai A, Shropshire WC, Suzuki M, Borjan J, Aitken SL, Bachman WC, McElheny CL, Bhatti MM, Shields RK, Shelburne SA, Doi Y. Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. mBio. 2024 Feb 14; 15(2):e0287423. PMID: 38179965; PMCID: PMC10865806.
      Citations:    Fields:    Translation:HumansCells
    7. Shropshire WC, Amiji H, Bremer J, Selvaraj Anand S, Strope B, Sahasrabhojane P, Gohel M, Aitken S, Spitznogle S, Zhan X, Kim J, Greenberg DE, Shelburne SA. Genetic determinants underlying the progressive phenotype of ?-lactam/?-lactamase inhibitor resistance in Escherichia coli. Microbiol Spectr. 2023 Dec 12; 11(6):e0222123. PMID: 37800937; PMCID: PMC10715226.
      Citations:    Fields:    Translation:HumansCells
    8. Shropshire WC, Endres BT, Borjan J, Aitken SL, Bachman WC, McElheny CL, Wu CT, Egge SL, Khan A, Miller WR, Bhatti MM, Saharasbhojane P, Kawai A, Shields RK, Shelburne SA, Doi Y. High-level ceftazidime/avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated ?-lactamase CMY-185 variant. J Antimicrob Chemother. 2023 10 03; 78(10):2442-2450. PMID: 37574665; PMCID: PMC10545501.
      Citations: 2     Fields:    Translation:HumansCells
    9. Axell-House DB, Simar SR, Panesso D, Rincon S, Miller WR, Khan A, Pemberton OA, Valdez L, Nguyen AH, Hood KS, Rydell K, DeTranaltes AM, Jones MN, Atterstrom R, Reyes J, Sahasrabhojane PV, Suleyman G, Zervos M, Shelburne SA, Singh KV, Shamoo Y, Hanson BM, Tran TT, Arias CA. LiaX is a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in Enterococcus faecium. bioRxiv. 2023 Aug 18. PMID: 37645818; PMCID: PMC10462152.
      Citations:    
    10. Shropshire WC, Strope B, Selvaraj Anand S, Bremer J, McDaneld P, Bhatti MM, Flores AR, Kalia A, Shelburne SA. Temporal dynamics of genetically heterogeneous extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections. mSphere. 2023 08 24; 8(4):e0018323. PMID: 37427953; PMCID: PMC10449519.
      Citations: 1     Fields:    Translation:HumansCells
    11. DebRoy S, Shropshire WC, Vega L, Tran C, Horstmann N, Mukherjee P, Selvaraj-Anand S, Tran TT, Bremer J, Gohel M, Arias CA, Flores AR, Shelburne SA. Identification of distinct impacts of CovS inactivation on the transcriptome of acapsular group A streptococci. mSystems. 2023 08 31; 8(4):e0022723. PMID: 37358280; PMCID: PMC10470059.
      Citations:    Fields:    Translation:HumansCells
    12. Horstmann N, Tran CN, Flores AR, Shelburne SA. Hyperphosphorylation of the Group A Streptococcal Control of Virulence Regulator Increases Promoter Occupancy Specifically at Virulence Factor-Encoding Genes. J Bacteriol. 2023 06 27; 205(6):e0011823. PMID: 37289078; PMCID: PMC10294628.
      Citations:    Fields:    Translation:HumansCells
    13. Shropshire WC, Strope B, Anand SS, Bremer J, McDaneld P, Bhatti MM, Flores AR, Kalia A, Shelburne SA. Temporal Dynamics of Genetically Heterogeneous Extended-Spectrum Cephalosporin Resistant Escherichia coli Bloodstream Infections. bioRxiv. 2023 Apr 11. PMID: 36798241; PMCID: PMC9934547.
      Citations:    
    14. McMahon S, Sahasrabhojane P, Kim J, Franklin S, Chang CC, Jenq RR, Hillhouse AE, Shelburne SA, Galloway-Pe?a J. Contribution of the Oral and Gastrointestinal Microbiomes to Bloodstream Infections in Leukemia Patients. Microbiol Spectr. 2023 06 15; 11(3):e0041523. PMID: 37022173; PMCID: PMC10269818.
      Citations: 1     Fields:    Translation:Humans
    15. Gerges B, Rolston K, Shelburne SA, Rosenblatt J, Prince R, Raad I. The in vitro activity of delafloxacin and comparator agents against bacterial pathogens isolated from patients with cancer. JAC Antimicrob Resist. 2023 Apr; 5(2):dlad034. PMID: 36994231; PMCID: PMC10041357.
      Citations: 1     
    16. Rolston K, Gerges B, Nesher L, Shelburne SA, Prince R, Raad I. In vitro activity of eravacycline and comparator agents against bacterial pathogens isolated from patients with cancer. JAC Antimicrob Resist. 2023 Apr; 5(2):dlad020. PMID: 36875177; PMCID: PMC9981869.
      Citations:    
    17. Shropshire WC, Endres BT, Borjan J, Aitken SL, Bachman WC, McElheny CL, Khan A, Bhatti MM, Saharasbhojane P, Kawai A, Shields RK, Shelburne SA, Doi Y. High-level ceftazidime-avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated beta-lactamase CMY-185 variant. bioRxiv. 2023 Feb 04. PMID: 36778324; PMCID: PMC9915728.
      Citations:    
    18. Hayase E, Hayase T, Mukherjee A, Stinson SC, Jamal MA, Ortega MR, Sanchez CA, Ahmed SS, Karmouch JL, Chang CC, Flores II, McDaniel LK, Brown AN, El-Himri RK, Chapa VA, Tan L, Tran BQ, Pham D, Halsey TM, Jin Y, Tsai WB, Prasad R, Glover IK, Ajami NJ, Wargo JA, Shelburne S, Okhuysen PC, Liu C, Fowler SW, Conner ME, Peterson CB, Rondon G, Molldrem JJ, Champlin RE, Shpall EJ, Lorenzi PL, Mehta RS, Martens EC, Alousi AM, Jenq RR. Bacteroides ovatus alleviates dysbiotic microbiota-induced intestinal graft-versus-host disease. Res Sq. 2023 Jan 31. PMID: 36778495; PMCID: PMC9915792.
      Citations:    
    19. Tran TT, Cabrera NL, Gonzales-Luna AJ, Carlson TJ, Alnezary F, Miller WR, Sakurai A, Dinh AQ, Rydell K, Rios R, Diaz L, Hanson BM, Munita JM, Pedroza C, Shelburne SA, Aitken SL, Garey KW, Dillon R, Puzniak L, Arias CA. Clinical characteristics, microbiology and outcomes of a cohort of patients treated with ceftolozane/tazobactam in acute care inpatient facilities, Houston, Texas, USA. JAC Antimicrob Resist. 2023 Feb; 5(1):dlac131. PMID: 36601551; PMCID: PMC9806660.
      Citations:    
    20. Simar SR, Tran TT, Rydell KB, Panesso D, Contreras GA, Munita JM, Cifuentes RO, Abbo LM, Sahasrabhojane P, Dinh AQ, Axell-House DB, Savidge T, Shelburne SA, Hanson BM, Arias CA. Multisite Detection of Tn1549-Mediated vanB Vancomycin Resistance in Multidrug-Resistant Enterococcus faecalis ST6 in Texas and Florida. Antimicrob Agents Chemother. 2023 01 24; 67(1):e0128422. PMID: 36541772; PMCID: PMC9872605.
      Citations:    Fields:    Translation:HumansCells
    21. Schwabkey ZI, Wiesnoski DH, Chang CC, Tsai WB, Pham D, Ahmed SS, Hayase T, Ortega Turrubiates MR, El-Himri RK, Sanchez CA, Hayase E, Frenk Oquendo AC, Miyama T, Halsey TM, Heckel BE, Brown AN, Jin Y, Raybaud M, Prasad R, Flores I, McDaniel L, Chapa V, Lorenzi PL, Warmoes MO, Tan L, Swennes AG, Fowler S, Conner M, McHugh K, Graf T, Jensen VB, Peterson CB, Do KA, Zhang L, Shi Y, Wang Y, Galloway-Pena JR, Okhuysen PC, Daniel-MacDougall CR, Shono Y, Burgos da Silva M, Peled JU, van den Brink MRM, Ajami N, Wargo JA, Reddy P, Valdivia RH, Davey L, Rondon G, Srour SA, Mehta RS, Alousi AM, Shpall EJ, Champlin RE, Shelburne SA, Molldrem JJ, Jamal MA, Karmouch JL, Jenq RR. Diet-derived metabolites and mucus link the gut microbiome to fever after cytotoxic cancer treatment. Sci Transl Med. 2022 11 16; 14(671):eabo3445. PMID: 36383683; PMCID: PMC10028729.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Tamma PD, Komarow L, Ge L, Garcia-Diaz J, Herc ES, Doi Y, Arias CA, Albin O, Saade E, Miller LG, Jacob JT, Satlin MJ, Krsak M, Huskins WC, Dhar S, Shelburne SA, Hill C, Baum KR, Bhojani M, Greenwood-Quaintance KE, Schmidt-Malan SM, Patel R, Evans SR, Chambers HF, Fowler VG, van Duin D, Antibacterial Resistance Leadership Group. Clinical Impact of Ceftriaxone Resistance in Escherichia coli Bloodstream Infections: A Multicenter Prospective Cohort Study. Open Forum Infect Dis. 2022 Nov; 9(11):ofac572. PMID: 36381622; PMCID: PMC9645644.
      Citations:    
    23. Hayase E, Hayase T, Jamal MA, Miyama T, Chang CC, Ortega MR, Ahmed SS, Karmouch JL, Sanchez CA, Brown AN, El-Himri RK, Flores II, McDaniel LK, Pham D, Halsey T, Frenk AC, Chapa VA, Heckel BE, Jin Y, Tsai WB, Prasad R, Tan L, Veillon L, Ajami NJ, Wargo JA, Galloway-Pe?a J, Shelburne S, Chemaly RF, Davey L, Glowacki RWP, Liu C, Rondon G, Alousi AM, Molldrem JJ, Champlin RE, Shpall EJ, Valdivia RH, Martens EC, Lorenzi PL, Jenq RR. Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease. Cell. 2022 09 29; 185(20):3705-3719.e14. PMID: 36179667; PMCID: PMC9542352.
      Citations: 20     Fields:    Translation:AnimalsCells
    24. Bhalodi AA, MacVane SH, Ford B, Ince D, Kinn PM, Percival KM, Bremmer DN, Carr DR, Walsh TL, Bhatti MM, Shelburne SA, Humphries RM, Wolfe K, Rosenbaum ER, Dare RK, Kolev J, Madhusudhan M, Ben-Aderet MA, Morgan MA. Real-World Impact of the Accelerate PhenoTest BC Kit on Patients With Bloodstream Infections in the Improving Outcomes and Antimicrobial Stewardship Study: A Quasiexperimental Multicenter Study. Clin Infect Dis. 2022 08 25; 75(2):269-277. PMID: 34718456; PMCID: PMC9410719.
      Citations: 1     Fields:    
    25. Vega LA, Sanson MA, Cubria MB, Regmi S, Shah BJ, Shelburne SA, Flores AR. The Integrative Conjugative Element ICESpyM92 Contributes to Pathogenicity of Emergent Antimicrobial-Resistant emm92 Group A Streptococcus. Infect Immun. 2022 08 18; 90(8):e0008022. PMID: 35913172; PMCID: PMC9387263.
      Citations:    
    26. Mojica MF, Humphries R, Lipuma JJ, Mathers AJ, Rao GG, Shelburne SA, Fouts DE, Van Duin D, Bonomo RA. Clinical challenges treating Stenotrophomonas maltophilia infections: an update. JAC Antimicrob Resist. 2022 Jun; 4(3):dlac040. PMID: 35529051; PMCID: PMC9071536.
      Citations:    
    27. Franklin S, Aitken SL, Shi Y, Sahasrabhojane PV, Robinson S, Peterson CB, Daver N, Ajami NA, Kontoyiannis DP, Shelburne SA, Galloway-Pe?a J. Oral and Stool Microbiome Coalescence and Its Association With Antibiotic Exposure in Acute Leukemia Patients. Front Cell Infect Microbiol. 2022; 12:848580. PMID: 35433514; PMCID: PMC9010033.
      Citations:    Fields:    Translation:Humans
    28. Shropshire WC, Dinh AQ, Earley M, Komarow L, Panesso D, Rydell K, Miao H, Hill C, Chen L, Patel R, Fries BC, Abbo L, Cober E, Revolinski S, Luterbach CL, Chambers H, Fowler VG, Bonomo RA, Shelburne SA, Kreiswirth BN, van Duin D, Hanson BM, Arias CA, G?mez-Villegas SI. Accessory Genomes Drive Independent Spread of Carbapenem-Resistant Klebsiella pneumoniae Clonal Groups 258 and 307 in Houston, TX. mBio. 2022 04 26; 13(2):e0049722. PMID: 35357213; PMCID: PMC9040855.
      Citations: 1     Fields:    Translation:HumansCells
    29. Rolston KVI, Gerges BZ, Reitzel R, Shelburne SA, Aitken SL, Raad II, Prince RA. In vitro activity of imipenem/releactam and comparator agents against clinical bacterial isolates from patients with cancer. J Glob Antimicrob Resist. 2022 06; 29:1-6. PMID: 35121163.
      Citations:    Fields:    Translation:HumansCells
    30. Contreras GA, Munita JM, Simar S, Luterbach C, Dinh AQ, Rydell K, Sahasrabhojane PV, Reyes K, Zervos M, Misikir HM, Sanchez-Petitto G, Liu C, Doi Y, Abbo LM, Shimose L, Seifert H, Gudiol C, Pedroza C, Aitken SL, Shelburne SA, van Duin D, Tran TT, Hanson BM, Arias CA, Rios R, Diaz L, Barberis F. Contemporary Clinical and Molecular Epidemiology of Vancomycin-Resistant Enterococcal Bacteremia: A Prospective Multicenter Cohort Study (VENOUS I). Open Forum Infect Dis. 2022 Mar; 9(3):ofab616. PMID: 35155713; PMCID: PMC8830530.
      Citations:    
    31. DebRoy S, Shropshire WC, Tran CN, Hao H, Gohel M, Hanson B, Flores AR, Shelburne SA, Galloway-Pe?a J. Characterization of the Type I Restriction Modification System Broadly Conserved among Group A Streptococci. mSphere. 2021 12 22; 6(6):e0079921. PMID: 34787444; PMCID: PMC8597746.
      Citations: 1     Fields:    Translation:HumansCells
    32. DebRoy S, Sanson M, Shah B, Regmi S, Vega LA, Odo C, Sahasrabhojane P, McGeer A, Tyrrell GJ, Fittipaldi N, Shelburne SA, Flores AR. Population Genomics of emm4 Group A Streptococcus Reveals Progressive Replacement with a Hypervirulent Clone in North America. mSystems. 2021 Aug 31; 6(4):e0049521. PMID: 34374563; PMCID: PMC8409732.
      Citations: 2     
    33. Sanson MA, Vega LA, Shah B, Regmi S, Cubria MB, Horstmann N, Shelburne SA, Flores AR. The LiaFSR Transcriptome Reveals an Interconnected Regulatory Network in Group A Streptococcus. Infect Immun. 2021 10 15; 89(11):e0021521. PMID: 34370508; PMCID: PMC8519277.
      Citations:    Fields:    Translation:AnimalsCells
    34. Olvera A, Carter H, Rajan A, Carlin LG, Yu X, Zeng XL, Shelburne S, Bhatti M, Blutt SE, Shroyer NF, Jenq R, Estes MK, Maresso A, Okhuysen PC. Enteropathogenic Escherichia coli Infection in Cancer and Immunosuppressed Patients. Clin Infect Dis. 2021 05 18; 72(10):e620-e629. PMID: 32930708; PMCID: PMC8130029.
      Citations: 2     Fields:    Translation:HumansCells
    35. Aitken SL, Sahasrabhojane PV, Kontoyiannis DP, Savidge TC, Arias CA, Ajami NJ, Shelburne SA, Galloway-Pe?a JR. Alterations of the Oral Microbiome and Cumulative Carbapenem Exposure Are Associated With Stenotrophomonas maltophilia Infection in Patients With Acute Myeloid Leukemia Receiving Chemotherapy. Clin Infect Dis. 2021 05 04; 72(9):1507-1513. PMID: 32544947; PMCID: PMC8096257.
      Citations: 6     Fields:    Translation:HumansCells
    36. Satlin MJ, Weissman SJ, Carpenter PA, Seo SK, Shelburne SA. American Society of Transplantation and Cellular Therapy Series, 1: Enterobacterales Infection Prevention and Management after Hematopoietic Cell Transplantation. Transplant Cell Ther. 2021 02; 27(2):108-114. PMID: 33781545.
      Citations: 1     Fields:    Translation:Humans
    37. Shropshire WC, Aitken SL, Pifer R, Kim J, Bhatti MM, Li X, Kalia A, Sahasrabhojane P, Arias CA, Greenberg DE, Hanson BM, Shelburne SA, Galloway-Pe?a J. IS26-mediated amplification of blaOXA-1 and blaCTX-M-15 with concurrent outer membrane porin disruption associated with de novo carbapenem resistance in a recurrent bacteraemia cohort. J Antimicrob Chemother. 2021 01 19; 76(2):385-395. PMID: 33164081; PMCID: PMC7816169.
      Citations: 7     Fields:    Translation:Humans
    38. DebRoy S, Arora S, Liang X, Horstmann N, Hook M, Flores AR, Shelburne SA, Aliaga-Tobar V, Galvez G, Maracaja-Coutinho V, Latorre M. Genome-wide analysis of in vivo CcpA binding with and without its key co-factor HPr in the major human pathogen group A Streptococcus. Mol Microbiol. 2021 06; 115(6):1207-1228. PMID: 33325565; PMCID: PMC8359418.
      Citations: 5     Fields:    Translation:Cells
    39. Shah S, Shelburne S. Skin and Soft Tissue Infections in Non-Human Immunodeficiency Virus Immunocompromised Hosts. Infect Dis Clin North Am. 2021 Mar; 35(1):199-217. PMID: 33303336.
      Citations:    Fields:    Translation:HumansPHPublic Health
    40. Reyes-Gibby CC, Wang J, Zhang L, Peterson CB, Do KA, Jenq RR, Shelburne S, Shah DP, Chambers MS, Hanna EY, Yeung SJ, Shete S. Oral microbiome and onset of oral mucositis in patients with squamous cell carcinoma of the head and neck. Cancer. 2020 12 01; 126(23):5124-5136. PMID: 32888342; PMCID: PMC8191575.
      Citations: 5     Fields:    Translation:Humans
    41. Shi Y, Peterson CB, Sahasrabhojane P, Gopalakrishnan V, Brumlow CE, Daver NG, Alfayez M, Boddu PC, Khan MAW, Wargo JA, Do KA, Jenq RR, Kontoyiannis DP, Shelburne SA, Galloway-Pe?a JR. Gut Microbiome Signatures Are Predictive of Infectious Risk Following Induction Therapy for Acute Myeloid Leukemia. Clin Infect Dis. 2020 06 24; 71(1):63-71. PMID: 31436833; PMCID: PMC7312220.
      Citations: 27     Fields:    Translation:Humans
    42. Hanage WP, Shelburne SA. Streptococcus pyogenes With Reduced Susceptibility to ?-Lactams: How Big an Alarm Bell? Clin Infect Dis. 2020 06 24; 71(1):205-206. PMID: 31630163.
      Citations: 2     Fields:    Translation:HumansCells
    43. Rolston KVI, Gerges B, Shelburne S, Aitken SL, Raad I, Prince RA. Activity of Cefiderocol and Comparators against Isolates from Cancer Patients. Antimicrob Agents Chemother. 2020 04 21; 64(5). PMID: 32071053; PMCID: PMC7179642.
      Citations: 15     Fields:    Translation:HumansCells
    44. Robinson S, Peterson CB, Sahasrabhojane P, Ajami NJ, Shelburne SA, Kontoyiannis DP, Galloway-Pe?a JR. Observational Cohort Study of Oral Mycobiome and Interkingdom Interactions over the Course of Induction Therapy for Leukemia. mSphere. 2020 04 15; 5(2). PMID: 32295867; PMCID: PMC7160678.
      Citations: 9     Fields:    Translation:HumansAnimals
    45. Flores AR, Shelburne SA. Toward an Understanding of Group A Streptococcal Transmission Dynamics Using National-level Surveillance. Clin Infect Dis. 2020 03 17; 70(7):1482-1483. PMID: 31408107.
      Citations:    Fields:    Translation:HumansCellsPHPublic Health
    46. Cabrera NL, Malek AE, Shelburne S, Taremi M, Awadh H, Francisco D, Robins A, Jabbour E, Chemaly RF. Disseminated cytomegalovirus infection with bilateral adrenal pseudotumors masquerading as recurrent hematologic malignancy. Infection. 2020 Jun; 48(3):477-481. PMID: 32144592.
      Citations:    Fields:    Translation:HumansCells
    47. Arora S, Li X, Hillhouse A, Konganti K, Little SV, Lawhon SD, Threadgill D, Shelburne S, Hook M. Staphylococcus epidermidis MSCRAMM SesJ Is Encoded in Composite Islands. mBio. 2020 02 18; 11(1). PMID: 32071265; PMCID: PMC7029136.
      Citations: 6     Fields:    Translation:HumansCells
    48. Kim J, Greenberg DE, Pifer R, Jiang S, Xiao G, Shelburne SA, Koh A, Xie Y, Zhan X. VAMPr: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning. PLoS Comput Biol. 2020 01; 16(1):e1007511. PMID: 31929521; PMCID: PMC7015433.
      Citations: 19     Fields:    Translation:Cells
    49. Minhaj AA, Dupuis CJ, Ensor JE, Golardi N, Jaso JM, Dixon KA, Figueira TA, Hill L, Shelburne SA, Tam AL, Mu?oz NM, Galloway-Pe?a JR. What Are the Effects of Irreversible Electroporation on a Staphylococcus aureus Rabbit Model of Osteomyelitis? Clin Orthop Relat Res. 2019 Oct; 477(10):2367-2377. PMID: 31393339; PMCID: PMC6999922.
      Citations: 2     Fields:    Translation:AnimalsCells
    50. Flores AR, Chase McNeil J, Shah B, Van Beneden C, Shelburne SA. Capsule-Negative emm Types Are an Increasing Cause of Pediatric Group A Streptococcal Infections at a Large Pediatric Hospital in Texas. J Pediatric Infect Dis Soc. 2019 Jul 01; 8(3):244-250. PMID: 30085121; PMCID: PMC8938855.
      Citations: 15     Fields:    Translation:HumansCells
    51. Peterson CB, Malik F, Sahasrabhojane PV, Shah DP, Brumlow CE, Carlin LG, Chemaly RF, Im JS, Rondon G, Felix E, Veillon L, Lorenzi PL, Alousi AM, Jenq RR, Kontoyiannis DP, Shpall EJ, Shelburne SA, Okhuysen PC, Galloway-Pe?a JR. Fecal Microbiome, Metabolites, and Stem Cell Transplant Outcomes: A Single-Center Pilot Study. Open Forum Infect Dis. 2019 May; 6(5):ofz173. PMID: 31065565; PMCID: PMC6499899.
      Citations: 20     
    52. Benanti GE, Brown ART, Shigle TL, Tarrand JJ, Bhatti MM, McDaneld PM, Shelburne SA, Aitken SL. Carbapenem versus Cefepime or Piperacillin-Tazobactam for Empiric Treatment of Bacteremia Due to Extended-Spectrum-?-Lactamase-Producing Escherichia coli in Patients with Hematologic Malignancy. Antimicrob Agents Chemother. 2019 02; 63(2). PMID: 30509935; PMCID: PMC6355563.
      Citations: 7     Fields:    Translation:HumansCells
    53. Tran TT, Mishra NN, Seepersaud R, Diaz L, Rios R, Dinh AQ, Rybak MJ, Shelburne SA, Sullam PM, Bayer AS, Arias CA, Garcia-de-la-Maria C, Miro JM. Mutations in cdsA and pgsA Correlate with Daptomycin Resistance in Streptococcus mitis and S. oralis. Antimicrob Agents Chemother. 2019 02; 63(2). PMID: 30509945; PMCID: PMC6355606.
      Citations: 10     Fields:    Translation:HumansCells
    54. DebRoy S, Brumlow C, Li X, Tran TT, Horstmann N, Yao H, Chen K, Wang F, Pan BF, Hawke DH, Thompson EJ, Arias CA, Fowler VG, Bhatti MM, Kalia A, Flores AR, Shelburne SA, Galloway-Pe?a J. Hypervirulent group A Streptococcus emergence in an acaspular background is associated with marked remodeling of the bacterial cell surface. PLoS One. 2018; 13(12):e0207897. PMID: 30517150; PMCID: PMC6281247.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    55. DebRoy S, Li X, Kalia A, Galloway-Pena J, Shah BJ, Fowler VG, Flores AR, Shelburne SA. Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus. Microb Genom. 2018 11; 4(11). PMID: 30412460; PMCID: PMC6321872.
      Citations: 6     Fields:    Translation:HumansCells
    56. Horstmann N, Tran CN, Brumlow C, DebRoy S, Yao H, Nogueras Gonzalez G, Makthal N, Kumaraswami M, Shelburne SA. Phosphatase activity of the control of virulence sensor kinase CovS is critical for the pathogenesis of group A streptococcus. PLoS Pathog. 2018 10; 14(10):e1007354. PMID: 30379939; PMCID: PMC6231683.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    57. Foolad F, Taylor BD, Shelburne SA, Arias CA, Aitken SL. Association of daptomycin dosing regimen and mortality in patients with VRE bacteraemia: a review. J Antimicrob Chemother. 2018 09 01; 73(9):2277-2283. PMID: 29547977; PMCID: PMC6454563.
      Citations: 6     Fields:    Translation:HumansCells
    58. Lacourt TE, Kavelaars A, Ohanian M, Shah ND, Shelburne SA, Futreal A, Kontoyiannis DP, Heijnen CJ. Patient-reported fatigue prior to treatment is prognostic of survival in patients with acute myeloid leukemia. Oncotarget. 2018 Jul 27; 9(58):31244-31252. PMID: 30131851; PMCID: PMC6101294.
      Citations: 4     Fields:    
    59. Li X, Arias CA, Aitken SL, Panesso D, Chang M, Diaz L, Rios R, Numan Y, Ghaoui S, DebRoy S, Bhatti MM, Simmons DE, Raad I, Hachem R, Folan SA, Sahasarabhojane P, Kalia A, Shelburne SA, Galloway Pe?a J. Clonal Emergence of Invasive Multidrug-Resistant Staphylococcus epidermidis Deconvoluted via a Combination of Whole-Genome Sequencing and Microbiome Analyses. Clin Infect Dis. 2018 07 18; 67(3):398-406. PMID: 29546356; PMCID: PMC6051468.
      Citations: 13     Fields:    Translation:HumansCells
    60. Folan SA, Marx KR, Tverdek FP, Raad I, Mulanovich VE, Tarrand JJ, Shelburne SA, Aitken SL. Clinical Outcomes Associated With Linezolid Resistance in Leukemia Patients With Linezolid-Resistant Staphylococcus epidermidis Bacteremia. Open Forum Infect Dis. 2018 Jul; 5(7):ofy167. PMID: 30090838; PMCID: PMC6061807.
      Citations:    
    61. Rolston KVI, Reitzel R, Vargas-Cruz N, Shelburne SA, Raad II, Prince RA. In vitro activity of tedizolid and comparator agents against clinical Gram-positive isolates recovered from patients with cancer. Diagn Microbiol Infect Dis. 2018 Aug; 91(4):351-353. PMID: 29661529.
      Citations: 2     Fields:    Translation:HumansCells
    62. Lacourt TE, Kavelaars A, Sahasrabhojane PV, Shah ND, Futreal A, Kontoyiannis DP, Shelburne SA, Heijnen CJ, Galloway-Pe?a JR. Associations of inflammation with symptom burden in patients with acute myeloid leukemia. Psychoneuroendocrinology. 2018 03; 89:203-208. PMID: 29414033.
      Citations: 4     Fields:    Translation:Humans
    63. Shelburne SA, Kim J, Munita JM, Sahasrabhojane P, Shields RK, Press EG, Li X, Arias CA, Cantarel B, Jiang Y, Kim MS, Aitken SL, Greenberg DE. Whole-Genome Sequencing Accurately Identifies Resistance to Extended-Spectrum ?-Lactams for Major Gram-Negative Bacterial Pathogens. Clin Infect Dis. 2017 09 01; 65(5):738-745. PMID: 28472260; PMCID: PMC5850535.
      Citations: 23     Fields:    Translation:HumansCells
    64. Horstmann N, Sahasrabhojane P, Yao H, Su X, Shelburne SA. Use of a Phosphorylation Site Mutant To Identify Distinct Modes of Gene Repression by the Control of Virulence Regulator (CovR) in Streptococcus pyogenes. J Bacteriol. 2017 09 15; 199(18). PMID: 28289082; PMCID: PMC5573087.
      Citations: 11     Fields:    Translation:Cells
    65. Brumlow C, Shelburne S, Galloway-Pe?a J. Impact of the Microbiota on Bacterial Infections during Cancer Treatment. Trends Microbiol. 2017 12; 25(12):992-1004. PMID: 28728967.
      Citations: 12     Fields:    Translation:Humans
    66. Reyes-Gibby CC, Melkonian SC, Wang J, Yu RK, Shelburne SA, Lu C, Gunn GB, Chambers MS, Hanna EY, Yeung SJ, Shete S. Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis. PLoS One. 2017; 12(7):e0180396. PMID: 28678827; PMCID: PMC5498049.
      Citations: 4     Fields:    Translation:Humans
    67. Munita JM, Aitken SL, Miller WR, Perez F, Rosa R, Shimose LA, Lichtenberger PN, Abbo LM, Jain R, Nigo M, Wanger A, Araos R, Tran TT, Adachi J, Rakita R, Shelburne S, Bonomo RA, Arias CA. Multicenter Evaluation of Ceftolozane/Tazobactam for Serious Infections Caused by Carbapenem-Resistant Pseudomonas aeruginosa. Clin Infect Dis. 2017 07 01; 65(1):158-161. PMID: 28329350; PMCID: PMC5850333.
      Citations: 50     Fields:    Translation:HumansCells
    68. Flores AR, Luna RA, Runge JK, Shelburne SA, Baker CJ. Cluster of Fatal Group A Streptococcal emm87 Infections in a Single Family: Molecular Basis for Invasion and Transmission. J Infect Dis. 2017 06 01; 215(11):1648-1652. PMID: 28383686.
      Citations: 11     Fields:    Translation:HumansCells
    69. Wadsworth WD, Argiento R, Guindani M, Galloway-Pena J, Shelburne SA, Vannucci M. Erratum to: An integrative Bayesian Dirichlet-multinomial regression model for the analysis of taxonomic abundances in microbiome data. BMC Bioinformatics. 2017 03 23; 18(1):185. PMID: 28335713; PMCID: PMC5363024.
      Citations:    Fields:    
    70. Jenq RR, Shelburne SA, Galloway-Pe?a JR. Can Consideration of the Microbiome Improve Antimicrobial Utilization and Treatment Outcomes in the Oncology Patient? Clin Cancer Res. 2017 07 01; 23(13):3263-3268. PMID: 28298544; PMCID: PMC5496798.
      Citations: 12     Fields:    Translation:Humans
    71. Smith DP, Sahasrabhojane P, Wadsworth WD, Fellman BM, Ajami NJ, Shpall EJ, Daver N, Guindani M, Petrosino JF, Kontoyiannis DP, Shelburne SA, Galloway-Pe?a JR. Characterization of oral and gut microbiome temporal variability in hospitalized cancer patients. Genome Med. 2017 02 28; 9(1):21. PMID: 28245856; PMCID: PMC5331640.
      Citations: 38     Fields:    Translation:HumansCells
    72. Rolston KVI, Jamal MA, Nesher L, Shelburne SA, Raad I, Prince RA. In vitro activity of ceftaroline and comparator agents against Gram-positive and Gram-negative clinical isolates from cancer patients. Int J Antimicrob Agents. 2017 Apr; 49(4):416-421. PMID: 28257904.
      Citations: 4     Fields:    Translation:HumansCells
    73. Wadsworth WD, Argiento R, Guindani M, Galloway-Pena J, Shelburne SA, Vannucci M. An integrative Bayesian Dirichlet-multinomial regression model for the analysis of taxonomic abundances in microbiome data. BMC Bioinformatics. 2017 02 08; 18(1):94. PMID: 28178947; PMCID: PMC5299727.
      Citations: 14     Fields:    Translation:HumansCells
    74. Munita JM, Shelburne S, Greenberg DE, Arias CA. The Growing Threat of Antimicrobial Resistance. Tex Med. 2017 Feb 01; 113(2):48-52. PMID: 28207079.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    75. Bhatti MD, Kalia A, Sahasrabhojane P, Kim J, Greenberg DE, Shelburne SA. Identification and Whole Genome Sequencing of the First Case of Kosakonia radicincitans Causing a Human Bloodstream Infection. Front Microbiol. 2017; 8:62. PMID: 28174569; PMCID: PMC5258702.
      Citations: 3     
    76. DiPippo AJ, Tverdek FP, Tarrand JJ, Tran TT, Arias CA, Shelburne SA, Aitken SL, Munita JM. Daptomycin non-susceptible Enterococcus faecium in leukemia patients: Role of prior daptomycin exposure. J Infect. 2017 03; 74(3):243-247. PMID: 27845153; PMCID: PMC5324836.
      Citations: 9     Fields:    Translation:HumansCells
    77. DebRoy S, Travisany D, Montano A, Horstmann N, Yao H, Maass A, Latorre M, Shelburne SA, Salda?a M, Galloway-Pe?a J, Gonz?lez M. A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus. Sci Rep. 2016 09 01; 6:32442. PMID: 27580596; PMCID: PMC5007534.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    78. Mojica MF, Ouellette CP, Leber A, Becknell MB, Ardura MI, Perez F, Shimamura M, Bonomo RA, Aitken SL, Shelburne SA. Successful Treatment of Bloodstream Infection Due to Metallo-?-Lactamase-Producing Stenotrophomonas maltophilia in a Renal Transplant Patient. Antimicrob Agents Chemother. 2016 09; 60(9):5130-4. PMID: 27551008; PMCID: PMC4997835.
      Citations: 29     Fields:    Translation:HumansCells
    79. Zhu L, Olsen RJ, Horstmann N, Shelburne SA, Fan J, Hu Y, Musser JM. Intergenic Variable-Number Tandem-Repeat Polymorphism Upstream of rocA Alters Toxin Production and Enhances Virulence in Streptococcus pyogenes. Infect Immun. 2016 07; 84(7):2086-2093. PMID: 27141081; PMCID: PMC4936349.
      Citations: 14     Fields:    Translation:AnimalsCells
    80. Aitken SL, Tarrand JJ, Deshpande LM, Tverdek FP, Jones AL, Shelburne SA, Prince RA, Bhatti MM, Rolston KVI, Jones RN, Castanheira M, Chemaly RF. High Rates of Nonsusceptibility to Ceftazidime-avibactam and Identification of New Delhi Metallo-?-lactamase Production in Enterobacteriaceae Bloodstream Infections at a Major Cancer Center. Clin Infect Dis. 2016 10 01; 63(7):954-958. PMID: 27313265.
      Citations: 23     Fields:    Translation:HumansCells
    81. Smith DP, Sahasrabhojane P, Ajami NJ, Wadsworth WD, Daver NG, Chemaly RF, Marsh L, Ghantoji SS, Pemmaraju N, Garcia-Manero G, Rezvani K, Alousi AM, Wargo JA, Shpall EJ, Futreal PA, Guindani M, Petrosino JF, Kontoyiannis DP, Shelburne SA, Galloway-Pe?a JR. The role of the gastrointestinal microbiome in infectious complications during induction chemotherapy for acute myeloid leukemia. Cancer. 2016 07 15; 122(14):2186-96. PMID: 27142181; PMCID: PMC5574182.
      Citations: 56     Fields:    Translation:Humans
    82. Petrosyan V, Holder M, Ajami NJ, Petrosino JF, Sahasrabhojane P, Thompson EJ, Kalia A, Shelburne SA. Complete Genome Sequence of Streptococcus mitis Strain SVGS_061 Isolated from a Neutropenic Patient with Viridans Group Streptococcal Shock Syndrome. Genome Announc. 2016 Apr 07; 4(2). PMID: 27056234; PMCID: PMC4824267.
      Citations: 3     
    83. Shukla BS, Shelburne S, Reyes K, Kamboj M, Lewis JD, Rincon SL, Reyes J, Carvajal LP, Panesso D, Sifri CD, Zervos MJ, Pamer EG, Tran TT, Adachi J, Munita JM, Hasbun R, Arias CA. Influence of Minimum Inhibitory Concentration in Clinical Outcomes of Enterococcus faecium Bacteremia Treated With Daptomycin: Is it Time to Change the Breakpoint? Clin Infect Dis. 2016 06 15; 62(12):1514-1520. PMID: 27045126; PMCID: PMC4885651.
      Citations: 32     Fields:    Translation:HumansCells
    84. Clement ME, Sharma Kuinkel BK, Ruffin F, Flores AR, Levinson H, Shelburne SA, Moore Z, Fowler VG, Galloway-Pe?a J. Application of Whole-Genome Sequencing to an Unusual Outbreak of Invasive Group A Streptococcal Disease. Open Forum Infect Dis. 2016 Jan; 3(1):ofw042. PMID: 27006966; PMCID: PMC4800461.
      Citations: 9     
    85. Rolston KV, Wang W, Nesher L, Shelburne SA, Prince RA. In vitro activity of dalbavancin and five comparator agents against common and uncommon Gram-positive organisms isolated from cancer patients. J Antibiot (Tokyo). 2016 05; 69(5):381-7. PMID: 26626876.
      Citations: 2     Fields:    Translation:HumansCells
    86. Shelburne SA, Ajami NJ, Chibucos MC, Beird HC, Tarrand J, Albert N, Chemaly RF, Ghantoji SS, Marsh L, Pemmaraju N, Andreeff M, Shpall EJ, Wargo JA, Rezvani K, Alousi A, Bruno VM, Futreal PA, Petrosino JF, Kontoyiannis DP, Galloway-Pe?a J. Implementation of a Pan-Genomic Approach to Investigate Holobiont-Infecting Microbe Interaction: A Case Report of a Leukemic Patient with Invasive Mucormycosis. PLoS One. 2015; 10(11):e0139851. PMID: 26556047; PMCID: PMC4640583.
      Citations: 23     Fields:    Translation:HumansAnimals
    87. Miller EW, Danger JL, Ramalinga AB, Horstmann N, Shelburne SA, Sumby P. Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group A Streptococcus. Mol Microbiol. 2015 Oct; 98(3):473-89. PMID: 26192205; PMCID: PMC4675629.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    88. Teatero S, Athey TB, Van Caeseele P, Horsman G, Alexander DC, Melano RG, Li A, Flores AR, Shelburne SA, McGeer A, Demczuk W, Martin I, Fittipaldi N. Emergence of Serotype IV Group B Streptococcus Adult Invasive Disease in Manitoba and Saskatchewan, Canada, Is Driven by Clonal Sequence Type 459 Strains. J Clin Microbiol. 2015 Sep; 53(9):2919-26. PMID: 26135871; PMCID: PMC4540936.
      Citations: 23     Fields:    Translation:HumansCells
    89. Flores AR, Sahasrabhojane P, Yao H, Su X, Ajami NJ, Holder ME, Petrosino JF, Thompson E, Margarit Y Ros I, Rosini R, Grandi G, Horstmann N, Teatero S, McGeer A, Fittipaldi N, Rappuoli R, Baker CJ, Shelburne SA, Galloway-Pe?a J, Salda?a M. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. Proc Natl Acad Sci U S A. 2015 May 19; 112(20):6431-6. PMID: 25941374; PMCID: PMC4443349.
      Citations: 47     Fields:    Translation:HumansCells
    90. Horstmann N, Sahasrabhojane P, Ajami NJ, Flores AR, Sumby P, Liu CG, Yao H, Su X, Thompson E, Shelburne SA, Salda?a M. Characterization of the effect of the histidine kinase CovS on response regulator phosphorylation in group A Streptococcus. Infect Immun. 2015 Mar; 83(3):1068-77. PMID: 25561708; PMCID: PMC4333468.
      Citations: 30     Fields:    Translation:Cells
    91. Liang X, Singh KV, Yadav P, Chang C, La Rosa SL, Shelburne S, Ton-That H, Murray BE, Galloway-Pe?a JR, H??k M. The identification and functional characterization of WxL proteins from Enterococcus faecium reveal surface proteins involved in extracellular matrix interactions. J Bacteriol. 2015 Mar; 197(5):882-92. PMID: 25512313; PMCID: PMC4325096.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    92. Holland T, Fowler VG, Shelburne SA. Invasive gram-positive bacterial infection in cancer patients. Clin Infect Dis. 2014 Nov 15; 59 Suppl 5:S331-4. PMID: 25352626; PMCID: PMC4303051.
      Citations: 19     Fields:    Translation:HumansCells
    93. Shelburne SA, Chaftari AM, Jamal M, Al Wohoush I, Jiang Y, Abughazaleh S, Cairo J, Raad S, Debiane L, Raad I. Identification and characterization of catheter-related bloodstream infections due to viridans group streptococci in patients with cancer. Am J Infect Control. 2014 Oct; 42(10):1127-9. PMID: 25278410.
      Citations: 6     Fields:    Translation:HumansCells
    94. Flores AR, Jewell BE, Olsen RJ, Shelburne SA, Fittipaldi N, Beres SB, Musser JM. Asymptomatic carriage of group A streptococcus is associated with elimination of capsule production. Infect Immun. 2014 Sep; 82(9):3958-67. PMID: 25024363; PMCID: PMC4187823.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    95. Sahasrabhojane P, Tarrand J, Han XY, Shelburne SA, Galloway-Pe?a J. GyrB polymorphisms accurately assign invasive viridans group streptococcal species. J Clin Microbiol. 2014 Aug; 52(8):2905-12. PMID: 24899021; PMCID: PMC4136163.
      Citations: 10     Fields:    Translation:HumansCells
    96. Rolston K, Wang W, Nesher L, Coyle E, Shelburne S, Prince RA. In vitro activity of telavancin compared with vancomycin and linezolid against Gram-positive organisms isolated from cancer patients. J Antibiot (Tokyo). 2014 Jul; 67(7):505-9. PMID: 24824818.
      Citations: 3     Fields:    Translation:HumansCells
    97. Horstmann N, Sahasrabhojane P, Yao H, Su X, Thompson E, Koller A, Shelburne SA, Salda?a M. Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis. PLoS Pathog. 2014 May; 10(5):e1004088. PMID: 24788524; PMCID: PMC4006921.
      Citations: 44     Fields:    Translation:AnimalsCells
    98. Shelburne SA, Sahasrabhojane P, Saldana M, Yao H, Su X, Horstmann N, Thompson E, Flores AR. Streptococcus mitis strains causing severe clinical disease in cancer patients. Emerg Infect Dis. 2014 May; 20(5):762-71. PMID: 24750901; PMCID: PMC4012796.
      Citations: 62     Fields:    Translation:HumansAnimalsCells
    99. Shelburne SA, Lasky RE, Sahasrabhojane P, Tarrand JT, Rolston KV. Development and validation of a clinical model to predict the presence of ?-lactam resistance in viridans group streptococci causing bacteremia in neutropenic cancer patients. Clin Infect Dis. 2014 Jul 15; 59(2):223-30. PMID: 24755857.
      Citations: 9     Fields:    Translation:HumansCells
    100. Sahasrabhojane P, Velazquez L, Horstmann N, Tarrand J, Shelburne SA, Galloway-Pe?a J, Salda?a M. Species-level assessment of the molecular basis of fluoroquinolone resistance among viridans group streptococci causing bacteraemia in cancer patients. Int J Antimicrob Agents. 2014 Jun; 43(6):558-62. PMID: 24721231.
      Citations: 3     Fields:    Translation:HumansCells
    101. El Zakhem A, Chaftari AM, Bahu R, El Helou G, Shelburne S, Jiang Y, Hachem R, Raad I. Central line-associated bloodstream infections caused by Staphylococcus aureus in cancer patients: Clinical outcome and management. Ann Med. 2014 May; 46(3):163-8. PMID: 24491173.
      Citations: 9     Fields:    Translation:HumansCells
    102. Flores AR, Sahasrabhojane P, Olsen RJ, Musser JM, Shelburne SA, Salda?a M, Galloway-Pe?a J. Molecular characterization of an invasive phenotype of group A Streptococcus arising during human infection using whole genome sequencing of multiple isolates from the same patient. J Infect Dis. 2014 May 15; 209(10):1520-3. PMID: 24307742; PMCID: PMC3997578.
      Citations: 15     Fields:    Translation:HumansCells
    103. Flores AR, Olsen RJ, Wunsche A, Kumaraswami M, Shelburne SA, Carroll RK, Musser JM. Natural variation in the promoter of the gene encoding the Mga regulator alters host-pathogen interactions in group a Streptococcus carrier strains. Infect Immun. 2013 Nov; 81(11):4128-38. PMID: 23980109; PMCID: PMC3811816.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    104. Shelburne SA, Tarrand J, Rolston KV. Review of streptococcal bloodstream infections at a comprehensive cancer care center, 2000-2011. J Infect. 2013 Feb; 66(2):136-46. PMID: 23182968.
      Citations: 7     Fields:    Translation:HumansCells
    105. White CN, Shelburne S. Streptococcal infections: understanding the various species and strains. JAAPA. 2012 Nov; 25(11):23-4. PMID: 23620919.
      Citations:    Fields:    Translation:HumansCells
    106. Horstmann N, Orans J, Valentin-Hansen P, Shelburne SA, Brennan RG. Structural mechanism of Staphylococcus aureus Hfq binding to an RNA A-tract. Nucleic Acids Res. 2012 Nov; 40(21):11023-35. PMID: 22965117; PMCID: PMC3505971.
      Citations: 21     Fields:    Translation:Cells
    107. Olsen RJ, Laucirica DR, Watkins ME, Feske ML, Garcia-Bustillos JR, Vu C, Cantu C, Shelburne SA, Fittipaldi N, Kumaraswami M, Shea PR, Flores AR, Beres SB, Lovgren M, Tyrrell GJ, Efstratiou A, Low DE, Van Beneden CA, Musser JM. Polymorphisms in regulator of protease B (RopB) alter disease phenotype and strain virulence of serotype M3 group A Streptococcus. J Infect Dis. 2012 Jun; 205(11):1719-29. PMID: 22262791; PMCID: PMC4447876.
      Citations: 20     Fields:    Translation:HumansAnimalsCells
    108. Lin E, Bhusal Y, Horwitz D, Shelburne SA, Trautner BW. Overtreatment of enterococcal bacteriuria. Arch Intern Med. 2012 Jan 09; 172(1):33-8. PMID: 22232145.
      Citations: 19     Fields:    Translation:HumansCells
    109. Shelburne SA, Olsen RJ, Makthal N, Brown NG, Sahasrabhojane P, Watkins EM, Palzkill T, Musser JM, Kumaraswami M. An amino-terminal signal peptide of Vfr protein negatively influences RopB-dependent SpeB expression and attenuates virulence in Streptococcus pyogenes. Mol Microbiol. 2011 Dec; 82(6):1481-95. PMID: 22040048; PMCID: PMC4571278.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    110. Horstmann N, Sahasrabhojane P, Suber B, Kumaraswami M, Olsen RJ, Flores A, Musser JM, Brennan RG, Shelburne SA. Distinct single amino acid replacements in the control of virulence regulator protein differentially impact streptococcal pathogenesis. PLoS Pathog. 2011 Oct; 7(10):e1002311. PMID: 22028655; PMCID: PMC3197619.
      Citations: 31     Fields:    Translation:AnimalsCells
    111. Shelburne SA, Sahasrobhajane P, Suber B, Keith DB, Davenport MT, Horstmann N, Kumaraswami M, Olsen RJ, Brennan RG, Musser JM. Niche-specific contribution to streptococcal virulence of a MalR-regulated carbohydrate binding protein. Mol Microbiol. 2011 Jul; 81(2):500-14. PMID: 21645132; PMCID: PMC3147245.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    112. Carroll RK, Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Kumaraswami M, Beres SB, Shea PR, Flores AR, Musser JM. Naturally occurring single amino acid replacements in a regulatory protein alter streptococcal gene expression and virulence in mice. J Clin Invest. 2011 May; 121(5):1956-68. PMID: 21490401; PMCID: PMC3083769.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    113. Kung DH, Hubenthal EA, Kwan JY, Shelburne SA, Goodman JC, Kass JS. Toxoplasmosis myelopathy and myopathy in an AIDS patient: a case of immune reconstitution inflammatory syndrome? Neurologist. 2011 Jan; 17(1):49-51. PMID: 21192196.
      Citations: 10     Fields:    Translation:Humans
    114. Shelburne SA, Olsen RJ, Suber B, Sahasrabhojane P, Sumby P, Brennan RG, Musser JM. A combination of independent transcriptional regulators shapes bacterial virulence gene expression during infection. PLoS Pathog. 2010 Mar 19; 6(3):e1000817. PMID: 20333240; PMCID: PMC2841617.
      Citations: 36     Fields:    Translation:HumansAnimalsCells
    115. Musser JM, Shelburne SA. A decade of molecular pathogenomic analysis of group A Streptococcus. J Clin Invest. 2009 Sep; 119(9):2455-63. PMID: 19729843; PMCID: PMC2735924.
      Citations: 45     Fields:    Translation:HumansCells
    116. Safdar A, Shelburne SA, Evans SE, Dickey BF. Inhaled therapeutics for prevention and treatment of pneumonia. Expert Opin Drug Saf. 2009 Jul; 8(4):435-49. PMID: 19538104; PMCID: PMC4527977.
      Citations: 18     Fields:    Translation:HumansAnimals
    117. Perez N, Liu Z, Shelburne SA, Musser JM, Sumby P, Trevi?o J, Ramirez-Pe?a E. CovS simultaneously activates and inhibits the CovR-mediated repression of distinct subsets of group A Streptococcus virulence factor-encoding genes. Infect Immun. 2009 Aug; 77(8):3141-9. PMID: 19451242; PMCID: PMC2715666.
      Citations: 76     Fields:    Translation:HumansAnimalsCells
    118. Shelburne SA. Empirical use of fluconazole in critically ill patients: good study, but what was the hold-up? Ann Intern Med. 2009 Jan 06; 150(1):58-9; author reply 59-60. PMID: 19124825.
      Citations:    Fields:    Translation:Humans
    119. Olsen RJ, Shelburne SA, Musser JM. Molecular mechanisms underlying group A streptococcal pathogenesis. Cell Microbiol. 2009 Jan; 11(1):1-12. PMID: 18710460.
      Citations: 54     Fields:    Translation:HumansAnimalsCells
    120. Shelburne SA, Keith DB, Davenport MT, Horstmann N, Brennan RG, Musser JM. Molecular characterization of group A Streptococcus maltodextrin catabolism and its role in pharyngitis. Mol Microbiol. 2008 Jul; 69(2):436-52. PMID: 18485073; PMCID: PMC2761070.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    121. Livorsi DJ, Daver NG, Atmar RL, Shelburne SA, White AC, Musher DM. Outcomes of treatment for hematogenous Staphylococcus aureus vertebral osteomyelitis in the MRSA ERA. J Infect. 2008 Aug; 57(2):128-31. PMID: 18562009.
      Citations: 18     Fields:    Translation:HumansCells
    122. Shelburne SA, Davenport MT, Keith DB, Musser JM. The role of complex carbohydrate catabolism in the pathogenesis of invasive streptococci. Trends Microbiol. 2008 Jul; 16(7):318-25. PMID: 18508271; PMCID: PMC2975494.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    123. Shelburne SA, Keith D, Horstmann N, Sumby P, Davenport MT, Graviss EA, Brennan RG, Musser JM. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus. Proc Natl Acad Sci U S A. 2008 Feb 05; 105(5):1698-703. PMID: 18230719; PMCID: PMC2234207.
      Citations: 107     Fields:    Translation:HumansAnimalsCells
    124. Shelburne SA, Singh KV, White AC, Byrne L, Carmer A, Austin C, Graviss E, Stager C, Murray BE, Atmar RL. Sequential outbreaks of infections by distinct Acinetobacter baumannii strains in a public teaching hospital in Houston, Texas. J Clin Microbiol. 2008 Jan; 46(1):198-205. PMID: 18003801; PMCID: PMC2224270.
      Citations: 13     Fields:    Translation:HumansCellsPHPublic Health
    125. Shelburne SA, Okorafor N, Sitkiewicz I, Sumby P, Keith D, Patel P, Austin C, Graviss EA, Musser JM. Regulation of polysaccharide utilization contributes to the persistence of group a streptococcus in the oropharynx. Infect Immun. 2007 Jun; 75(6):2981-90. PMID: 17403878; PMCID: PMC1932865.
      Citations: 16     Fields:    Translation:HumansCells
    126. Shelburne SA, Fang H, Okorafor N, Sumby P, Sitkiewicz I, Keith D, Patel P, Austin C, Graviss EA, Musser JM, Chow DC. MalE of group A Streptococcus participates in the rapid transport of maltotriose and longer maltodextrins. J Bacteriol. 2007 Apr; 189(7):2610-7. PMID: 17259319; PMCID: PMC1855798.
      Citations: 18     Fields:    Translation:Cells
    127. Daver NG, Shelburne SA, Atmar RL, Giordano TP, Stager CE, Reitman CA, White AC. Oral step-down therapy is comparable to intravenous therapy for Staphylococcus aureus osteomyelitis. J Infect. 2007 Jun; 54(6):539-44. PMID: 17198732.
      Citations: 25     Fields:    Translation:HumansCells
    128. Gonzalez BE, Rueda AM, Shelburne SA, Musher DM, Hamill RJ, Hulten KG. Community-associated strains of methicillin-resistant Staphylococccus aureus as the cause of healthcare-associated infection. Infect Control Hosp Epidemiol. 2006 Oct; 27(10):1051-6. PMID: 17006811.
      Citations: 51     Fields:    Translation:HumansCells
    129. Shelburne SA, Sumby P, Sitkiewicz I, Okorafor N, Granville C, Patel P, Voyich J, Hull R, DeLeo FR, Musser JM. Maltodextrin utilization plays a key role in the ability of group A Streptococcus to colonize the oropharynx. Infect Immun. 2006 Aug; 74(8):4605-14. PMID: 16861648; PMCID: PMC1539623.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    130. Kaka AS, Rueda AM, Shelburne SA, Hulten K, Hamill RJ, Musher DM. Bactericidal activity of orally available agents against methicillin-resistant Staphylococcus aureus. J Antimicrob Chemother. 2006 Sep; 58(3):680-3. PMID: 16840428.
      Citations: 17     Fields:    Translation:HumansCells
    131. Shelburne SA, Greenberg SB, Aslam S, Tweardy DJ. Successful ceftriaxone therapy of endocarditis due to penicillin non-susceptible viridans streptococci. J Infect. 2007 Feb; 54(2):e99-101. PMID: 16824611.
      Citations: 1     Fields:    Translation:HumansCells
    132. Shelburne SA, Montes M, Hamill RJ. Immune reconstitution inflammatory syndrome: more answers, more questions. J Antimicrob Chemother. 2006 Feb; 57(2):167-70. PMID: 16354748.
      Citations: 83     Fields:    Translation:Humans
    133. Shelburne SA, Sumby P, Sitkiewicz I, Granville C, DeLeo FR, Musser JM. Central role of a bacterial two-component gene regulatory system of previously unknown function in pathogen persistence in human saliva. Proc Natl Acad Sci U S A. 2005 Nov 01; 102(44):16037-42. PMID: 16249338; PMCID: PMC1276065.
      Citations: 48     Fields:    Translation:HumansCells
    134. Shelburne SA, Visnegarwala F, Adams C, Krause KL, Hamill RJ, White AC. Unusual manifestations of disseminated Histoplasmosis in patients responding to antiretroviral therapy. Am J Med. 2005 Sep; 118(9):1038-41. PMID: 16164892.
      Citations: 1     Fields:    Translation:Humans
    135. Shelburne SA, Granville C, Tokuyama M, Sitkiewicz I, Patel P, Musser JM. Growth characteristics of and virulence factor production by group A Streptococcus during cultivation in human saliva. Infect Immun. 2005 Aug; 73(8):4723-31. PMID: 16040985; PMCID: PMC1201272.
      Citations: 42     Fields:    Translation:HumansCells
    136. Shelburne SA, Visnegarwala F, Darcourt J, Graviss EA, Giordano TP, White AC, Hamill RJ. Incidence and risk factors for immune reconstitution inflammatory syndrome during highly active antiretroviral therapy. AIDS. 2005 Mar 04; 19(4):399-406. PMID: 15750393.
      Citations: 182     Fields:    Translation:HumansCells
    137. Shelburne SA, Darcourt J, White AC, Greenberg SB, Hamill RJ, Atmar RL, Visnegarwala F. The role of immune reconstitution inflammatory syndrome in AIDS-related Cryptococcus neoformans disease in the era of highly active antiretroviral therapy. Clin Infect Dis. 2005 Apr 01; 40(7):1049-52. PMID: 15825000.
      Citations: 92     Fields:    Translation:Humans
    138. Shelburne SA, Musher DM, Hulten K, Ceasar H, Lu MY, Bhaila I, Hamill RJ. In vitro killing of community-associated methicillin-resistant Staphylococcus aureus with drug combinations. Antimicrob Agents Chemother. 2004 Oct; 48(10):4016-9. PMID: 15388469; PMCID: PMC521878.
      Citations: 12     Fields:    Translation:HumansCells
    139. Shelburne SA, Musser JM. Virulence gene expression in vivo. Curr Opin Microbiol. 2004 Jun; 7(3):283-9. PMID: 15196497.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    140. Shelburne SA, Kielhofner MA, Tiwari PS. Cerebellar involvement in legionellosis. South Med J. 2004 Jan; 97(1):61-4. PMID: 14746424.
      Citations: 12     Fields:    Translation:Humans
    141. Shelburne SA, Hamill RJ. The immune reconstitution inflammatory syndrome. AIDS Rev. 2003 Apr-Jun; 5(2):67-79. PMID: 12876896.
      Citations: 58     Fields:    Translation:Humans
    142. Shelburne SA, Hamill RJ, Rodriguez-Barradas MC, Greenberg SB, Atmar RL, Musher DW, Gathe JC, Visnegarwala F, Trautner BW. Immune reconstitution inflammatory syndrome: emergence of a unique syndrome during highly active antiretroviral therapy. Medicine (Baltimore). 2002 May; 81(3):213-27. PMID: 11997718.
      Citations: 157     Fields:    Translation:Humans
    143. Regulatory rewiring confers serotype-specific hyper-virulence in the human pathogen group A Streptococcus. Molecular Microbiology. 98:473-489.
    144. Influence of Minimum Inhibitory Concentration in Clinical Outcomes of Enterococcus faecium Bacteremia Treated with Daptomycin. Clinical Infectious Diseases. 62:1514-1520.
    145. Intergenic variable-number tandem-repeat polymorphism upstream of rocA alters toxin production and enhances virulence in Streptococcus pyogenes. Infection and Immunity. 84:2086-2093.
    146. Emergence of serotype IV group B streptococcus adult invasive disease in Manitoba and saskatchewan, Canada, is driven by clonal sequence type 459 strains. Journal of Clinical Microbiology. 53:2919-2926.
    147. Immune reconstitution inflammatory syndrome. 699-706.
    148. Successful treatment of bloodstream infection due to metallo-β-lactamase-producing Stenotrophomonas maltophilia in a renal transplant patient. Antimicrobial Agents and Chemotherapy. 60:5130-5134.
    149. Immune reconstitution inflammatory syndrome. Journal of Antimicrobial Chemotherapy. 58:1094-1095.
    150. Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes. Proceedings of the National Academy of Sciences of the United States of America. 112:6431-6436.
    151. Application of whole-genome sequencing to an unusual outbreak of invasive group a streptococcal disease. Open Forum Infectious Diseases. 3.
    152. Daptomycin non-susceptible Enterococcus faecium in leukemia patients. Journal of Infection.
    153. High Rates of Nonsusceptibility to Ceftazidime-avibactam and Identification of New Delhi Metallo-β-lactamase Production in Enterobacteriaceae Bloodstream Infections at a Major Cancer Center. Clinical Infectious Diseases. 63:954-958.
    154. A direct link between carbohydrate utilization and virulence in the major human pathogen group A Streptococcus (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, 5, (1698-1703) DOI. Proceedings of the National Academy of Sciences of the United States of America. 106:8790.
    155. In vitro activity of dalbavancin and five comparator agents against common and uncommon Gram-positive organisms isolated from cancer patients. Journal of Antibiotics. 69:381-387.
    156. Implementation of a pan-genomic approach to investigate holobiont-infecting microbe interaction. PLoS One. 10.
    157. A Multi-Serotype Approach Clarifies the Catabolite Control Protein A Regulon in the Major Human Pathogen Group A Streptococcus. Scientific Reports. 6.
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